15/9/2 (Item 2 from file: 10)

3230901 92067455 Holding Library: AGL

Dual cannulation: a method for continuous intravenous infusion and

repeated blood sampling in unrestrained mice

Hodge, D.E. Shalev, M.

Mount Sinai Medical Center, New York, NY

Cordova, Tenn. : American Association for Laboratory Animal Science.

Laboratory animal science. June 1992. v. 42 (3) p. 320‑322.

ISSN: 0023‑6764 CODEN: LBASA

DNAL Call Number: 410.9 P94

Language: English

Includes references.

Subfile: OTHER US (NOT EXP STN, EXT, USDA; SINCE 12/76) ;

Document Type: Article

Descriptors: mice ‑ blood sampling ‑ cannulation ‑ infusion ‑

intravenous injection ‑ jugular vein ‑ methodology ;

Section Headings: L800 VETERINARY SCIENCE AND HYGIENE; L110 LABORATORY

AND EXPERIMENTAL ANIMALS

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15/9/10 (Item 7 from file: 155)

09411343 98113514

Genomic DNA from mice: a comparison of recovery methods and tissue

sources.

Hofstetter JR; Zhang A; Mayeda AR; Guscar T; Nurnberger JI Jr; Lahiri

Department of Psychiatry, Indiana University School of Medicine,

Indianapolis 46202, USA.

Biochemical and molecular medicine ( UNITED STATES ) Dec 1997 , 62

(2) p197‑202 , ISSN 1077‑3150 Journal Code: B3J

Languages: ENGLISH

Document type: JOURNAL ARTICLE

Journal Announcement: 9805

Subfile: INDEX MEDICUS

Our aim is to identify an extraction method and the source of mouse

tissue(s) that could allow a high‑resolution genomic scan from a living

mouse. We compared and optimized two methods for yield, purity of DNA,

and their use in the polymerase chain reaction (PCR) of DNA extracted

from different mouse tissues. In addition to whole blood, tissue samples

from the brain, liver, testis, and tail were included in this study. The

Rapid Method (RM) is preferable for the whole blood samples and testis

and brain tissue samples because it is quicker, less toxic, and more

cost‑effective than the proteinase K method (PM). For liver the PM

produced higher yields of DNA with less degradation than the RM. For tail

tip, the PM produced a higher yield of DNA, but the RM resulted in a

higher yield of PCR product. From a living mouse, a tail snip generated a

sufficient amount of DNA for several hundred PCRs but not a complete

genomic scan. We suggest that the RM can be used to extract genomic DNA

for a complete genomic scan which requires either testicular tissues or

repeated blood samples from the suborbital sinus over several months

without sacrificing the animal.

Tags: Animal; Comparative Study; Male; Support, Non‑U.S. Gov't

Descriptors: *DNA‑‑Isolation and Purification‑‑IP; *Organ

Specificity‑‑Genetics‑‑GE ; Brain Chemistry‑‑Genetics‑‑GE;

DNA‑‑Blood‑‑BL; Genome; Liver‑‑Chemistry‑‑CH ; Mice; Mice, Inbred C57BL;

Polymerase Chain Reaction; Tail‑‑Chemistry‑‑CH; Testis‑‑Chemistry‑‑CH

CAS Registry No.: 9007‑49‑2 (DNA)

MEDLINE(R) (Dialog« File 155): (c) format only 2000 Dialog Corporation. All

rights reserved.

15/9/13 (Item 10 from file: 155)

08964275 97101988

Repeated blood collection in the laboratory mouse by tail

incision‑‑modification of an old technique.

Durschlag M; Wurbel H; Stauffacher M; Von Holst D

Department of Animal Physiology, University of Bayreuth, Germany.

tenderly@ltk.unizh.ch

Physiology & behavior ( UNITED STATES ) Dec 1996 , 60 (6) p1565‑8 ,

ISSN 0031‑9384 Journal Code: P72

Languages: ENGLISH

Document type: JOURNAL ARTICLE

Journal Announcement: 9705

Subfile: INDEX MEDICUS

Twenty years ago, tail incision for collecting serial blood samples

from mice was introduced as a new technique. Despite a number of

advantages over established methods, it has not become a frequently used

technique. This report describes modifications of blood collection from

mice by tail incision that allow obtaining rapid (1‑1.5 min) serial blood

samples (40‑150 microliters) from unanaesthetized laboratory mice.

Evaluation of corticosterone concentrations in the blood plasma from

repeated samples indicated that subsequent samples were unaffected by the

procedure. Furthermore, histopathological examination demonstrated that

repeated bleeding did not cause any lasting harm to the animals. Blood

collection by tail incision may, therefore, be of particular interest for

studies that attempt to relate physiological measures to behavioral

responses in laboratory mice, and may contribute to the refinement of

animal experimentation according to the principles of the Three Rs.

Tags: Animal; Male; Support, Non‑U.S. Gov't

Descriptors: *Blood Specimen Collection‑‑Methods‑‑MT;

*Research‑‑Methods‑‑MT; *Tail ‑‑Ultrastructure‑‑UL ; Mice; Mice, Inbred

ICR

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rights reserved.

15/9/21 (Item 18 from file: 155)

03906742 83278215

Increased white blood cell counts and immunoglobulin concentrations in

BALB/c mice after repeated weekly bleeding.

Nielsen E

Zeitschrift fur Versuchstierkunde ( GERMANY, EAST ) 1983 , 25 (2)

p78‑83 , ISSN 0044‑3697 Journal Code: Y2B

Languages: ENGLISH

Document type: JOURNAL ARTICLE

Journal Announcement: 8311

Subfile: INDEX MEDICUS

Tags: Animal; Female; Male

Descriptors: *Immunoglobulins‑‑Metabolism‑‑ME;

*Leukocytes‑‑Cytology‑‑CY; *Mice‑‑Blood ‑‑BL ; Blood Specimen

Collection‑‑Veterinary‑‑VE; Leukocyte Count‑‑Veterinary‑‑VE; Mice, Inbred

BALB C

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rights reserved.

15/9/23 (Item 20 from file: 155)

02026948 75192897

A simple technic for repeated collection of blood samples from mice.

Stoltz DR; Bendall RD

Laboratory animal science ( UNITED STATES ) Jun 1975 , 25 (3)

p353‑4 , ISSN 0023‑6764 Journal Code: KYS

Languages: ENGLISH

Document type: JOURNAL ARTICLE

Journal Announcement: 7511

Subfile: INDEX MEDICUS

A device for repeated collection of small blood samples from mice was

constructed from a plastic syringe. Blood was collected into a 3.33

lambda capillary tube. Bleeding was stopped by a hemostat made from a

rubber stopper. This technic allows easy collection of approximately 20

serial samples within an 8‑hr period.

Tags: Animal

Descriptors: *Blood Specimen Collection‑‑Veterinary‑‑VE;

*Mice‑‑Blood‑‑BL ; Blood Specimen Collection‑‑Methods‑‑MT; Syringes; Time

Factors

MEDLINE(R) (Dialog« File 155): (c) format only 2000 Dialog Corporation. All

rights reserved.

15/9/38 (Item 5 from file: 5)

00819350 Biosis No.: 000008039477

INHIBITION OF ANTIBODY ACTIVITY DURING REPEATED BLEEDINGS OF A

PHYSIOLOGICAL ORDER OF MAGNITUDE

Author: ZEMSKOV M V; ZHURAVLEVA N V

Journal: BULL EXP BIOL MED (ENGL TRANSL BYULL EKS BIOL MED) 72 (9).

1971‑1972 1054‑1056

CODEN: BEXBA

Record Type: Citation

Descriptors: RABBIT MOUSE ALBUMIN FRACTION SERUM PROTEIN LIVER EXTRACTS

BLOOD SERUM

Concept Codes:

Alternate Indexing: 13012 Metabolism‑Proteins, Peptides and Amino Acids

14004 Digestive System‑Physiology and Biochemistry

15002 Blood, Blood‑Forming Organs and Body Fluids‑Blood and Lymph

Studies

34508 Immunology and Immunochemistry‑Immunopathology, Tissue Immunology

10064 Biochemical Studies‑Proteins, Peptides and Amino Acids

14501 Cardiovascular System‑General; Methods

Biosystematic Codes:

86040 Leporidae

86375 Muridae

Biosystematic Classification (SUPER TAXA):

Animals

Chordates

Vertebrates

Nonhuman Vertebrates

Mammals

Nonhuman Mammals

Lagomorphs

Rodents

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1 2001 The Dialog Corporation