Animal Welfare Information Center Newsletter, Fall 1994, Vol. 5, no. 3

Grants

• Developing and Improving Institutional Animal Resources
• Avian Research
• Mechanistically - Based Alternative Methods in Toxicology: RFA #ES-94-009
• Advanced Biomedical Technology SOL BAA #94-14

• Developing and Improving Institutional Animal Resources

  The National Center for Research Resources (NCRR) encourages the submission of individual animal resource improvement grant applications from biomedical research institutions. The major objectives of this program are to upgrade animal facilities, develop administratively centralized programs of animal care, and enable institutions to comply with the USDA Animal Welfare Act and Department of Health and Human Services policies related to the care and use of laboratory animals. Support is limited to alterations and renovations to improve laboratory animal facilities, and the purchase of major equipment items for animal resources, diagnostic laboratories, transgenic animal resources, or similar associated activities. Eligibility, application procedures, deadlines, and program details can be found in NIH Guide, volume 23, number 27, July 22, 1994, PA Number PAR-94-083. Inquiries about the program can be directed to:

  Director, Laboratory Animal Sciences Program
  Comparative Medicine Program
  National Center for Research Resources
  Westwood Building, Rm. 857
  Bethesda, MD 20892-4500
  Tel: (301) 594-7933
  Fax: (301) 594-7955

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• Avian Research The Association of Avian Veterinarians (AAV) offers grants for avian research with clinical applications. The AAV is an international professional organization dedicated to the advancement and promotion of avian medicine and stewardship. Grant information can be obtained through the central office: Adina Rae Freedman, Executive Director, P.O. Box 811720, Boca Raton, FL 33481; Tel: (407) 393-8901; Fax: (407) 393-8902

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• Mechanistically - Based Alternative Methods in Toxicology: RFA #ES-94-009
  
  The National Institute of Environmental Health Sciences has announced a request for applications (RFA) entitled "Mechanistically-Based Alternative Methods in Toxicology."
  
  The RFA is being issued to foster the development, validation, and use of improved testing and research methods and models that either do not require the use of animals, that reduce the number of animals used, or that involve the use of alternatives such as non-mammalian species. It is anticipated that improved testing methods that incorporate new knowledge regarding the molecular and cellular mechanisms of toxicity will be developed and validated, and existing test methods will be refined to use new scientific information and techniques. Toxicological test methods/model systems are encouraged in the priority areas of carcinogenicity, neurotoxicity, and developmental toxicity, but will be considered for any area of toxicity testing. Examples of alternative methods and models that may be appropriate for development under this program include genetically engineered cell lines, non-mammalian and invertebrate species, transgenic animals, and computer-based prediction and modeling systems.
  
  The anticipated funding level (total cost) is $ 1.5 million per year for 3 years, and it is estimated that 8 to 10 grants will be awarded. Applications must be received by December 20, 1994. The anticipated date of award is July 1, 1995.
  
  A copy of the RFA can be obtained from Dr. Jerrold Heindel, Program Administrator, Organs and Systems Toxicology Branch, Division of Extramural Research and Training, MD 3-03, National Institute of Environmental Health Sciences, P.0. Box 12233, 104 T.W. Alexander Drive, Research Triangle Park, NC 27709.
  
  Telephone: 919-541-0781; FAX: 919-541-2843;
  E-mail: Heindel_J@NIEHS.NIH.GOV.
  The RFA is also available electronically via the Internet using either the GOPHER or MOSAIC client. The NIEHS gopher can be found on the "United States Government Gophers" list.

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• Advanced Biomedical Technology SOL BAA #94-14

  The Advanced Research Projects Agency (ARPA), U.S. Department of Defense, is initiating a program in Advanced Biomedical Technology with the focus of medical support on the battlefield. There is particular interest in those technologies which are of dual use -- i.e., have both commercial and military utility.
  
  Despite advances in medical care, casualties in the zone of close combat continue to constitute 90 percent of battlefield mortality. The majority of these die from exsanguination before being located by a medic or receiving definitive surgical care. The reason is that the practice of medicine has made poor use of emerging sensor and information technologies.
  
  The program is planned as a 5-year effort with initial awards totaling up to $6 million. Collaborative efforts are encouraged. Proposals are sought in the following areas, but other proposals that support the overall program objectives will be considered:
  
  1) Remote advanced diagnostics. One item is a small body-worn monitoring device of vital signs including blood pressure, pulse rate, ECG, and oxygen saturation. There is high interest that this device incorporate position location (keyed to a Global Positioning Satellite), friend or foe identification, and telecommunications. In addition there is strong interest in developing more extensive devices for non-invasive monitoring of vital body chemicals.
  
  2) Medical Simulation. The next critical advancement in medical education appears to require a virtual environment (cadaver) of human anatomy that permits education in basic and abnormal (e.g., military wounds) anatomy. Such a simulation should have realistic interaction capable of supporting surgical simulation for training. There is also interest in a virtual environment for individual simulated soldiers and medics which is compatible with SIM-NET for use in medical forces planning and training.
  
  The BAA will remain open until January 27, 1995. For more information, contact Dr. Richard Satava, ARPA/DSO, Advanced Research Projects Agency, 3701 N. Fairfax Dr., Arlington, VA 22203-1714. Fax: (703) 696-2201 Request a copy of BAA #94-14 and Guidelines for Proposal Submission.

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The Animal Welfare Information Center
U.S. Department of Agriculture
Agricultural Research Service
National Agricultural Library
10301 Baltimore Ave.
Beltsville, MD 20705-2351

Phone: (301) 504-6212
FAX: (301) 504-7125
E-mail: awic@nal.usda.gov

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