Animal Welfare Information Center Newsletter, Spring 1995, Vol. 6 No. 1 *************************

CAAT Seeks Refinement Information

The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) is dedicated to fostering the development of scientifically acceptable in vitro technologies and other alternatives for use in the development and safety evaluation of commercial and therapeutic products. Alternatives are defined as methods which reduce animal use, replace whole animal tests, or refine existing tests by minimizing animal distress.

CAAT is in the process of compiling data on the forgotten "R," refinement. We are soliciting descriptions of refinement methods, developed or established through personal laboratory experience, which decrease animal stress or discomfort. We intend to publish a collection of refinement methods for distribution to the scientific community. Our goal is two-fold: 1) to expose scientists to refinement methods, and 2) to provide a mechanism to encourage scientists who are already interested in alternatives to use identified refinement methods. All contributors will be acknowledged if their data/methods are included in the resulting publication.

Please review the following questions to determine if your work can be recognized as a refinement alternative. If you are able to answer yes to any of these questions, your experience in the laboratory most likely involved a refinement method suitable for inclusion in our study.

Please provide a summary of the refinement alternative that you have found to decrease animal discomfort or distress based on your personal experience with laboratory animals. In addition, please discuss the perceived impact of your refinement methods on the welfare of laboratory animals. We ask that you also include answers to the following questions in your report:

Send your summary to REFINE, Johns Hopkins Center for Alternatives to Animal Testing, 111 Market Place, Suite 840, Baltimore, MD 21202-6709. Tel: (410) 223-1693, Fax: (410) 223-1603, or e-mail:
subject: Refine

Please be sure to include your telephone/fax number or e-mail address so that we may contact you if we need further information.

This article appeared in the Animal Welfare Information Center Newsletter, Volume 6, Number 1, Spring 1995

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