Scientific Information Service (SIS) has been established by Wendy van Dok, Ph.D., a Melbourne toxicologist, to provide a scientific literature searching service that can provide information on alternatives to the use of animals or on ways to minimize pain and distress during animal experiments. Using databases available through several commercial organizations, SIS can provide continuous, comprehensive coverage of the international scientific literature. Results can be e-mailed to ensure quick delivery, and translation services are available. SIS can also compile bibliographies on any topic. For more information, contact Wendy van Dok, GPO Box 2579W, Melbourne, Vic. 3001 Australia, phone: (03) 9802 7211, fax: (03) 9802 0772, e-mail: wvandok@netspace.net.au
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The 2nd World Congress, held in Utrecht, The Netherlands, October 20-24, 1996, provided a global overview of the current status of reduction, refinement, and replacement alternatives. This publication, edited by L.F.M. van Zutphen, Utrecht University, and M. Balls, European Center for the Validation of Alternative Methods, provides an up-to-date overview of the various aspects dealing with the development, validation, and use of animal alternatives. In addition, current topics on animal welfare and ethical aspects of animal experiments are covered. Topics include humane endpoints, alternative animal models, noninvasive methods, databases, alternatives in toxicology, monoclonal and polyclonal antibodies, validation of alternative methods, regulatory viewpoints, etc. The publication has extensive subject and author indexes. The cost is NLG (Dutch guilders) 545 or US$ 340.75. 1260 pages. ISBN 0-444-82424-3
It is available from Elsevier Science, P.O. Box 945, New York, NY 10159-0945, phone: (212) 633-3730 or toll-free (888) 437-4636 (North America only), fax: (212) 633-3680, e-mail: usinfo-f@elsevier.com Elsevier Science, P.O. Box 211, 1000 AE Amsterdam, The Netherlands, phone: +(31) 20-485-3757, fax: +(31) 20-485-3432, e-mail: http://www.elsevier.com
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This series of texts will include topics such as animal consciousness, evolutionary psychology, animals in society, and cultural images of animal ethics. The first volume, Animal Consciousness and Animal Ethics, contains 15 chapters arranged in 3 sections Philosophy and Animal Consciousness, Science and Animal Consciousness, and Ethics and Animal Consciousness. The first part of the book covers the concept of consciousness in general and the way to acquire knowledge of conscious animal experiences. Part two covers the area of ethology and neuroscience with a discussion of theoretical and experimental approaches to animal consciousness, animal experiences, and their implications for animal welfare. Part three covers whether and how our treatment of animals should be based on animal experiences or whether other concepts are needed to give direction to humane treatment of animals. 264 pages.
To order or for additional information contact Van Gorcum Publishers, P.O. Box 43, NL-9400 AA Assen, The Netherlands, phone: 31 592 379555 fax: 31 592 372064, e-mail: assen@vgorcum.nl In the United States and Canada: contact Books International, Inc., P.O. Box 605, Herndon, VA 22070, phone: (703) 661-1500, fax: (703) 661-1501. The cost is NLG 59.90 or US$34.
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This survey was conducted in 1995 (see AWIC Newsletter Vol.5 #4 Winter 1994/95) to provide the National Institutes of Health (NIH) with information to "use in the planning and institution of programs to improve the quality and availability of laboratory animals, promote institutional care and humane treatment , improve facilities, and establish training programs in laboratory animal medicine. It will also contribute to the understanding of the effects of Federal, state, and local laws, regulations, and policies enacted to ensure humane care and to regulate the supply and cost of laboratory animals." The data collected is from fiscal year 1993. To order, contact the Office of Science and Health Reports, NIH, fax: (301) 480-3558, e-mail: ospio@ep.ncrr.nih.gov
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Comparative Medicine Resources, a new 94-page directory, describes more than 60 National Center for Research Resources (NCRR) supported resources and training awards available to the scientific community. These resources include seven Regional Primate Research Centers, special animal colonies and models, and animal information services. Available animal models include genetically defined strains of Drosophila melanogaster and Caenorhabditis elegans, laboratory reared Aplysia californica, transgenic mice and rats, specific-pathogen-free monkeys, and chimpanzees.
The directory summarizes each resource's current research efforts; provides details about available animal models, specimens, or services; lists key staff members; and describes procedures for accessing certain resources. To obtain a free copy of Comparative Medicine Resources directory, contact the Research Resources Information Center, 1601 Research Blvd., Rockville, MD 20850 USA, phone: (301) 838-6261, fax: (301) 838-6252, e-mail: rric@vitro.com The latest updates of the directory can be viewed on the NCRR web site at http://www.ncrr.nih.gov/ncrrprog/cmpdir/cmdirectory.asp
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On January 16, 1998, the Office for Protection from Research Risks and the Scientists Center for Animal Welfare (SCAW) will co-sponsor a 1-day workshop on Nonaffiliated and Nonscientist Members of IACUCs. The workshop will be held at the NIH Natcher Conference Center in Bethesda, Maryland. For more information or to register, contact Lee Krulisch, SCAW, 7833 Walker Drive, Suite 340, Greenbelt, MD 20770, phone: (301) 345-3500, fax: (301) 345-3503, e-mail: scaw@erols.com
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A 2-week intensive course on laboratory animal science will be organized at the Department of Laboratory Animal Science, Utrecht University, The Netherlands, from June 8 to 19, 1998. The objective of this course is to present basic facts and principles that are essential for the humane use of animals and for the quality of research. The contents of this course are in line with recommendations of the Federation of European Laboratory Animal Science Associations (FELASA) regarding the training of young scientists whose research involves the use of vertebrate animals. The course may also be of interest for those who intend to set up a similar course at their location. For this purpose, during the course, the acquisition of teaching materials can be discussed with the course committee. For information or for application forms, please contact Prof. dr. L. F. M. van Zutphen or Mrs. Marianne Albers, Department of Laboratory Animal Science, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.166, 3508 TD Utrecht, The Netherlands, phone: 31-30-2532033, fax: 31-30-2537997, e-mail: pdk@pobox.ruu.nl
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INVITOX is a workshop on in vitro toxicology held in Europe every 2 years. The aim of the workshop is to promote the exchange of views, information, and experience among scientists involved in the development and use of in vitro methods in toxicology and toxicity testing. The program will consist of six main sessions focused on recent advances, production and use of transgenic cells, acquisition and use of human cells, toxicity of complex materials, in vitro models for investigation of chronic toxicity and reversibility, and other topics. However, abstracts may be submitted on any aspect of in vitro toxicology. The meeting will be held at Sparsholt College, Hampshire, United Kingdom, from September 14-18, 1998. The number of participants is restricted to 170. For additional information, contact Caroline Sumner, INVITOX 98 Secretariat, Meetings Management, The Chestnuts, 1st Floor, 18 East Street, Farnham, Surrey GU9 7SD, United Kingdom, phone: +44 (0) 1252 726066, fax: +44 (0) 1252 723303, e-mail: jherriot@meetingsmgmy.u-net.com, World Wide Web: http://www.elsevier.nl/locate/invitox98
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The 38th annual Symposium of the Canadian Association for Laboratory Animal Science will be held June 21-24, 1998, at the Coast Plaza Hotel in Calgary, Alberta. The theme is "We Care: Training for Excellence. There will be forums on "Working with Industry" and "Training and the Three R's". Schedules workshops include: Laparoscopic Surgery; Experimental Design; Health, Safety and Liability in a Research Facility; Cardiovascular and Orthopedic Procedures; Immunological Diagnostic Procedures; Identification of Animals; Handling/Restraint Procedures in Cattle, Sheep and Goats; and Maintenance and Repair of Cage Wash and Surgical Equipment.
For more information contact Dr. Don McKay, CALAS/ASCAL, Biosciences Animal Service, CW 401 Biological Sciences Biulding, Edmonton, Alberta, Canada, T6G 2E9, phone: (403)492-5193, fax: (403)492-7257, e-mail: dmckay@gpu.srv.ualberta.ca
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CD-CANIS is a user-friendly, multimedia veterinary encyclopedia that was designed by clinical veterinarians. Disciplines covered by this CD-ROM include anesthesia, clinical pathology, behavior, medicine, parasitology, surgery, anatomy, diagnostic imaging, husbandry, microbiology, preventative medicine, pharmacology and therapeutics, etc. All major body systems are featured. All materials have been peer reviewed before their inclusion. The information retrieved is in full text with more than 2,000 pictures, video clips, sounds, and graphics. The CD is easy to search using several different search mechanisms. Each subscriber can receive a personalized copy of CD-CANIS to enable specific updates of topics of interest to be highlighted. Every 2 months, subscribers receive a new CD with fully revised and updated information. For more information, contact Mark Johnston, Vetstream plc, Langford Arch, Sawston, Cambridge, CB2 4EG United Kingdom, phone: + 44 (0) 1223 500123, fax: +44 (0) 1223 506565, e-mail: enquiries@vetstream.co.uk
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The University of California Davis School of Veterinary Medicine offers a series of programs on CD-ROM for veterinary medical education. These programs are just a sampling of the more than 180 instructional programs developed by the Computer Assisted Learning Facility (CALF) for use in the school's veterinary curriculum. Programs include The Equine Foot, Veterinary Neurosciences, Poisonous Plants, Veterinary Neuropathology, ParasitoLog, Equine Osteology Atlas and Quiz, Virtual Heart, Veterinary CPR Simulator, and Canine Osteology Atlas and Quiz. For more information, contact CALF at (916) 752-2477 or e-mail: rhayes@ucdavis.edu or jbkasper@ucdavis.edu
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Simulations of undergraduate laboratory experiments in physiology and pharmacology.
These generate simulated tissue responses, either from actual experimental results or from predictive models. Data are presented on the monitor screen, in high resolution graphics, in a form comparable to that in the real experiment such as storage oscilloscope or scrolling chart recorder. Students are expected to simulate many of the tasks associated with practical class teaching such as determining experimental parameters (from easy-to-use, Windows-like menus), and collecting data in much the same way as they would in the laboratory. They work at their own pace, and most students take readily to this form of teaching, often requesting to use the software in their own time for independent learning. The simulation programs make full use of color graphics and will run under a range of graphics drivers (CGA, EGA, VGA etc) on any IBM compatible machine. They are sold complete with multiuser license and documentation (program manual and, where appropriate, student's workbook and tutor's notes). All text in the programs may be edited by the teacher. This requires access to a simple text editor or word processor and means that teachers may alter existing text (for example, translate into different languages), add new text or assignments, and in effect tailor the program to their specific needs.
Some of these programs provide clinical data and feature case histories of typical clinical disorders. These sections are highly interactive and require students to interpret clinical test results and to make appropriate diagnoses. They also cover the physiological basis of the laboratory tests.
Interactive tutorials designed to support lectures or seminars. Text, graphics, and features such as animation and hypertext are combined with student-centered tasks and problems to produce quality learning aids suitable for independent study. These programs require a slightly higher specification machine (minimum 386 PC, 33 MHz, VGA graphics, and Microsoft Windows 3.1).
Programs include Introduction to Endocrinology, Rat Blood Pressure, Respiratory Pharmacology, Intestinal Motility, PK-SIMS (pharmakokinetic simulations), Drug Disposition Tutorials, Pharmacology of Inflammation, Neuromuscular Pharmacology, Langendorff Heart, Finkelman (simulation of the Finkelman preparation to teach pharmacology), Guinea Pig Ileum, Cat Nictitating Membrane, Epilepsy Tutorial, The Heart Tutorial, The Circulation Tutorial, Human Nervous System, Asthma, Cellular Respiration, Clinical Aspects of Pain, Squid Axon, Nerve Biophysics Tutorial, Blood Coagulation, Chest Clinic, Intestinal Absorption, Blood Physiology, Frog Heart, The Electrocardiogram, Exercise Physiology, Frog Skin (to study membrane transport of ions), Nerve Physiology, and Muscle Physiology.
For more information, contact David Dewhurst, Ph.D., Sheffield Bioscience Programs, 5 Woodlands Green, North Yorkshire HG2 8QD, United Kingdom, phone: +44 (0) 1423 888514, e-mail: d.dewhurst@lmu.ac.uk
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This newsletter, published by the Association of Veterinarians for Animal Rights (AVAR), contains valuable information for those looking for sources of alternatives in veterinary, medical, or graduate education. The newsletter also spotlights veterinary school programs that have implemented alternatives into their traditional curriculum (for example, Issue III 1996 focused on the School of Veterinary Medicine at Washington State University). For more information or to subscribe, contact AVAR, P.O. Box 208, Davis, CA 95617-0208 USA, phone: (916) 759-8106, fax: (916) 759-8116, e-mail: news:AVAR@igc.apc.org, World Wide Web: http://www.animalconcerns.org/avar/avar_www.htm
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The European Collection of Cell Cultures (ECACC) is based at the Centre for Applied Microbiology and Research (CAMR). CAMR is a Special Health Authority of the [United Kingdom] Department of Health. The collection is supported from a combination of sources, the UK Research Council, the European Community, the World Health Organization, and revenue from sales and the provision of technical services.
All distribution stocks of cell lines are tested for viability and for absence of mycoplasma. It is ECACC policy not to distribute mycoplasma infected material.
Cell lines designated "RCD" are part of the Research Council's Collection ampules from this collection are free of charge to UK nonprofit organizations; however, all requests are obliged to pay transportation costs. If a growing culture is required then a flask fee is charged.
Other collection deposits are available at ECACC's current standard charges.
Immunoclone Database
A European collaborative venture has formed a unique database specifically designed for researchers interested in immunoclones, such as monoclonal antibodies and T-cell receptors. The database provides a facility for on-line searches of specific antigens or immunoclones. U.S. orders Import permit requirements
It is an obligatory requirement for the importation of cell lines or their products into the United States that an application be made for a veterinary permit from the U.S. Department of Agriculture prior to shipment. The procedure for obtaining a permit is as follows:
For more information, contact the ECACC, Centre for Applied Microbiology and Research, Salisbury, Wilts SP4 OJG, United Kingdom, phone: +44 1980 612 512, fax: +44 1980 611 315, e-mail: ecacc@ecacc.demon.co.uk or contact the Centre Europeen de Recherche et de Developpement en Information et Communication Scientifiques (CERDIC), BP 295, 06905 Sophia Antipolis, France, phone/ fax : (33) 93 95 86 38. Orders can be placed by fax or post, they are unable to accept orders by telephone.
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David Seelig at Yale University has established an e-mail list devoted to discussion of topics in primate enrichment at biomedical and behavioral research laboratories. Individuals from zoological parks are also invited to participate. The list currently has 250 subscribers. If you are interested in participating, please send a message to david.seelig@yale.edu or visit the Primate Enrichment Forum website at http://pin.primate.wisc.edu/
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The home page of the UC Center for Animal Alternatives at the University of California at Davis School of Veterinary Medicine. The center places emphasis on distributing information about models, computer simulations, and other animal alternatives in education through every level of public and private education. It also seeks to provide investigators who use animals with information on the most current methods for improving all aspects of animal care.
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The center's goal is to promote and initiate research into animal welfare with a research emphasis on the neurophysiological basis for an animal's welfare. The page is in Dutch and English.
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The website provides information on the primary goals of the CCAC: assessment, education, and development of animal care guidelines. On-line requisition of many of their publications (Guide to the Care and Use of Experimental Animals, Orientation Package for Animal Care Committee Members, Animal Use Protocol Review, etc.) is available. The page is in English and French.
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You've read the newsletter, now check out their website! Provides general information about subscribing to their newsletter, list of enrichment videos available for loan (includes sample clips of some videos), enrichment conference and workshop announcements, publications, etc. Focuses on zoo animals, but many ideas may apply to other animals.
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Provides access to State statutes organized by topic. Topics include agriculture, fish and game, natural resources, etc. Many animal cruelty statutes can be found under agriculture.
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Photographs and text illustrate this blood-collection method developed by Annelise Hem and Per Solberg at the Laboratory Animal Centre of the Norwegian Institute of Public Health. The method as shown is performed at the University of Bergen and shows modifications developed at the vivarium of the university.
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These pages are an initial attempt to collect links to web pages and other sources containing teaching texts on subjects related to pure laboratory animal science. These include ethics, legislation, comparative biology, anatomy, pharmacology, physiology, genetics, anesthesia, analgesia, euthanasia, microbiology, environmental factors, experimental design, and techniques. Submission of URLs may be made to Adrian Smith, D.V.M., at e-mail: adrian.smith@veths.no
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Never seen the inside of an animal facility? Then check out the animal facility at the Norwegian College of Veterinary Medicine. This excellent virtual tour illustrates environmental enrichment techniques for rodents and mink and group housing of rabbits and provides information on alternatives to the use of animals.
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This searchable database is being developed by the Patuxent Wildlife Research Center, the U.S. National Park Service, and the U.S. Environmental Protection Agency.
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The Animal Welfare
Information Center
U.S. Department of
Agriculture
Agricultural Research
Service
National Agricultural
Library
10301 Baltimore Ave.
Beltsville, MD 20705-2351
Phone: (301) 504-6212
FAX: (301) 504-7125
E-mail: awic@nal.usda.gov
