Information Resources for Institutional Animal Care and Use Committees 1985-1999 *************************

Professional Guidelines





Bibliography


American Psychological Association Committee on Animal Research and Ethics (1994).Guidelines for ethical conduct in the care and use of animals.
Available at http://www.apa.org/science/anguide.html
Descriptors: justification of research, personnel, care and housing of animals, acquisition of animals, experimental procedures, euthanasia, field research, educational use of animals.

American Society of Ichthyologists and Herpetologists, The Herpetologists' League, and Society for the Study of Amphibians and Reptiles (1997).Guidelines for use of live amphibians and reptiles in field research. Charleston, South Carolina: American Society of Ichthyologists and Herpetologists.

Descriptors: general considerations, IACUCs, collecting, restraint and handling, marking, housing and maintenance at field sites, disposition following studies, references.

American Society of Ichthyologists and Herpetologists, American Fisheries Society, and American Institute of Fisheries Research Biologists (1988). Guidelines for use of fishes in field research. Fisheries 13(2): 16-23.
NAL call number: SH1.F54
Descriptors: general considerations, IACUCs, collecting, restraint and handling, marking, housing and maintenance at field sites, disposition following studies, references.

American Society of Mammalogists Animal Care and Use Committee (1998). Guidelines for the capture, handling, and care of mammals as approved by the American Society of Mammalogists. Journal of Mammalogy 79(4): 1416-1431.
2007 Update Available at http://www.mammalsociety.org/articles/guidelines-american-society-mammalogists-use-wild-mammals-research-0
NAL call number: 410 J823
Descriptors: background and history, field work in mammalogy, why mammalogists collect specimens, what is an adequate sample, sampling in threatened habitats, compliance with laws and regulations, methods for collecting specimens, live-trapping and netting, kill- trapping and shooting, methods for sampling tissues from live animals, responsibility for dependent offspring, social interactions, methods of euthanasia, methods for marking and tracking, holding and transporting captive animals, maintenance of wild-caught individuals in captivity, releasing previously captured live animals, health precautions.

Brown, M.J., P.T. Pearson, and F.N. Tomson (1993). Guidelines for animal surgery in research and teaching. AVMA Panel on Animal Surgery in Research and Teaching, and the ASLAP (American Society of Laboratory Animal Practitioners). American Journal of Veterinary Research 54 (9): 1544-1559.
NAL call number: 41.8 Am38
Descriptors: anesthesia standards , intraoperative care standards, postoperative care standards preoperative care standards, research methods, surgery, education, veterinary standards.

Canadian Council on Animal Care (1999). CCAC guidelines on: Choosing an appropriate endpoint in experiments using animals for research, teaching, and testing: Guiding principles. Ottawa, Ontario, Canada: Canadian Council on Animal Care.
Available at http://www.ccac.ca/Documents/Standards/Guidelines/Appropriate_endpoint.pdf
Descriptors: animal observation, significant indicators of pain and distress, scoring significant behavioral and physiological observations to set endpoints, pilot studies to determine appropriate endpoint, determining frequency of observations, defining responsibility for observations, training personnel in clinical animal observations, role of the IACUC, monoclonal antibody production, cancer research, toxicology, pain research, infectious disease studies, vaccine trials, animal models with potential for significant levels of pain and distress, species specific signs of pain and distress, information sources, understanding normal animal behavior, recognition and assessment of pain and distress, laboratory animals, fish, farm animals, examples of observational checklists used to determine endpoints.

Canadian Council on Animal Care (1999). CCAC guidelines on: institutional animal user training. Ottawa, Ontario, Canada: Canadian Council on Animal Care.
Available at http://www.ccac.ca/Documents/Standards/Guidelines/Institutional_training.pdf
Descriptors: philosophy of an animal user training program, course design, resource material, access to the training program, performance evaluation, recommended syllabus for an institutional animal user training program.

Canadian Council on Animal Care (1997). CCAC guidelines on: animal use protocol review, 1997. Ottawa, Ontario, Canada: Canadian Council on Animal Care.
Available at http://www.ccac.ca/Documents/Standards/Guidelines/Protocol_Review.pdf
Descriptors: general principles, potential benefit of the research, replacement alternatives, animal model selection, reduction of animal use/numbers, refinement of experimental technique, setting endpoints, physical restraint, invasive/stressful procedures, euthanasia, hazardous materials, teaching protocols, wildlife field studies, reading list.

Canadian Council on Animal Care (1997). CCAC guidelines on: transgenic animals, 1997. Ottawa, Ontario, Canada: Canadian Council on Animal Care.
Available at http://www.ccac.ca/Documents/Standards/Guidelines/Transgenic_Animals.pdf
Descriptors: methods used for production, investigator and animal care committee responsibilities, education, proposals to create new strains, proposals to use existing strains, accounting, containment, other regulations, reading list.

DeNardo, D. (1995). Amphibians as laboratory animals. ILAR Journal 37(4): 173-181.
NAL call number: QL55 A1I43
Descriptors: overview of species, anurans, frogs, salamanders, caecilians, vendors, captive breeding, field collection, importation, shipping, animal welfare regulations and policies, husbandry and housing, caging, heating, ventilation, and air conditioning, lighting, diet, water quality, sanitation, maintenance in the field, safety considerations, toxins, zoonoses, use in research, identification techniques, cage numbering, pattern marking, toe-clipping, tattooing and dye injecting, branding, tagging, transponder implantation, anesthesia--chemical, gas, hypothermia, surgery, euthanasiaphysical and chemical methods.

DeTolla, L.J., S. Srinivas, B.R. Whitaker, C. Andrews, B. Hecker, A.S. Kane, and R. Reimschuessel (1995). Guidelines for the care and use of fish in research. ILAR Journal 37(4): 159-173.
NAL call number: QL55 A1I43
Descriptors: principal investigator, animal care personnel, IACUC members, overview of current uses of fish in research and commerce, marine and freshwater species used in research, factors to consider when determining choice of species, vendors, ease of maintenance, space, sources of fish, state and federal permits and licenses, summary of applicable animal welfare laws and guidelines, developing procedures for housing, husbandry, and breeding, centralized facilities, construction materials, water quality, diet, temperatures, illumination, pH, salinity, alkalinity, and hardness, dissolved oxygen, nitrogen, artificial sea water, shipping, acclimation, quarantine, research laboratories, dangerous aquatic animals and safety conditions, traumatogenic animals, venomous fish, electrogenic animals, zoonoses, examples of uses of species in biomedical research, anesthesia, analgesia, and euthanasia--overview of available agents, IACUC protocol review.

Federation of Animal Sciences Societies (1999). Guide for the care and use of agricultural animals in agricultural research and teaching. Savoy, Illinois: Federation of Animal Sciences Societies, 120 p.
NAL call number: QL55 G8 1999
Descriptors: institutional policies, general guidelines for animal husbandry, animal health care, physical plant, beef cattle husbandry, dairy cattle husbandry, horse husbandry, poultry husbandry, sheep and goat husbandry, swine husbandry, veal calf husbandry, zoonotic diseases, anesthesia and analgesia, euthanasia, organizations.

Gaunt, A.S., L.S. Oring, K.P. Able, D.W. Anderson, L.F. Baptista, J.C. Barlow, and J.C. Wingfield (1999). Guidelines to the use of wild birds in research. Washington, D.C.: The Ornithological Council.
Available at http://www.nmnh.si.edu/BIRDNET/GuideToUse/index.html
Descriptors: IACUCs, permits, investigator impact, collecting and trapping, marking, transport, housing and captive breeding, major and minor manipulative procedures, anesthesia, euthanasia, code of ethics.

Greene, H.W. (1995). Nonavian reptiles as laboratory animals. ILAR Journal 37(4): 182-186.
NAL call number: QL55 A1I43
Descriptors: overview of species, composition, characteristics, and uses in research, species availability, vendors, captive breeding, field collection, shipping, husbandry and housing, heating, ventilation, lighting, air conditioning, diet, sanitation, safety considerations, toxins and other weaponry, zoonoses, identification techniques, anesthesia, euthanasia, surgery, animal welfare regulations and policies, behavioral complexity, ethical issues.

Guiding Principles for the Care and Use of Animals in the Field of Physiological Sciences (1990). Journal of the Physiological Society of Japan 52(1): 27-29.
NAL call number: QP1.N5
Descriptors: human, animal welfare, research, ethics, ACUC.

Health Canada (1996). Laboratory Biosafety Guidelines. Ottawa, Ontario: Health Protection Branch, Laboratory Centre for Disease Control.
Available at http://www.phac-aspc.gc.ca/ols-bsl/lbg-ldmbl/index.html
NAL call number: QH321.L33 1996
Descriptors: introduction, containment of biohazards, regulations, classification of biological agents according to risk, physical containment levels, large scale production of microorganisms, laboratory design, safety equipment, safety cabinets, fume hoods, filtration systems, bibliography, glossary.

Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council (1996). Guide for the Care and Use of Laboratory Animals, 7th Ed. Washington, D.C.: National Academy Press, 125p.
Available at http://www.nap.edu/openbook.php?record_id=5140
NAL call number: SF406.G95 1996.
Abstract: Incorporates recent research on commonly used species, including farm animals. Covers institutional policies and responsibilities, animal environment, husbandry, and management, veterinary care, and physical plant.
Descriptors: alternatives, laboratory animals, U.S. Public Health Service, laboratories, animal husbandry, veterinary care.

Institute of Laboratory Animal Resources (1991). Education and Training in the Care and Use of Laboratory Animals: A Guide for Developing Institutional Programs. National Academy of Sciences, Committee on Educational Programs in Laboratory Animal Science, Washington, DC: National Academy Press, 139 pp.
NAL call number: SF604.E3
Descriptors: laboratory animals, animal welfare, training, bibliography.

Institute of Laboratory Animal Resources (1990). Guia Para el Cuidado y uso de Animales de Laboratorio. Revisada en 1985. Translation of: Guide for the Care and Use of Laboratory Animals NIH publication no. 90-23S. Committee on Care and Use of Laboratory Animals, U.S. Department of Health and Human Services, Public Health Service, Bethesda, Maryland: National Institutes of Health, 83 pp.
NAL call number: SF406.G8 1990
Descripciones: animales del laboratorio, bienestar de animales, entrenimiento, bibliografia.

Jackson, L.R. and J.G. Fox (1995). Institutional policies and guidelines on adjuvants and antibody production. ILAR Journal 37(3): 141-152.
NAL call number: QL55 A1I43
Descriptors: summary of policies from 30 facilities in the United States, monoclonal antibodies, selection of animals, immunization protocols, priming agents, inoculation of hybridoma cells, abdominal paracentesis, clinical observations, alternatives, polyclonal antibodies, selection of animals, antigen preparation, antigen-adjuvant emulsions, Freund's adjuvants and alternatives, injection site selection and preparation, routes, volumes, and sites of administration, post-injection observations, blood collection, restraint, institutional resources, personnel safety.

Jackson, R.K. (1997). Unusual laboratory rodent species: Research uses, care and associated biohazards. ILAR Journal 38(1): 13-21.
NAL call number: QL55 A1I43
Descriptors: wild rodent species, voles, deer mice, cotton rats, ground squirrels, trumpet- tailed rats or degus, multimammate rat, woodchucks, uses in research, special husbandry considerations, potential zoonoses and biohazards.

National Institutes of Health (1992). Using Animals in Intramural Research, Guidelines for Investigators. Bethesda, Maryland: NIH Animal Care and Use Committee.
NAL call number: HV4928.U84 1992.
Descriptors: laboratory animals, animal experimentation, animal welfare.

National Institutes of Health (1994). Using Animals in Intramural Research, Guidelines for Investigators and Guidelines for Animal Users. Bethesda, Maryland: NIH Animal Research Advisory Committee, Office of Animal Care and Use.
NAL call number: HV4928.U85 1994.
Descriptors: animal experimentation, laboratory animals, animal welfare, federal guidelines.

National Institutes of Health (1992). Institutional Animal Care and Use Committee Guidebook, NIH Publication no. 92-3415.Washington, D.C.: U.S. Government Printing Office.
NAL call number: HV4764.I58 1992.
Descriptors: laboratory animals, animal experimentation, animal welfare.

Pough, H. (1992). Recommendations for the care of amphibians and reptiles in academic institutions. Washington, D.C.: National Academy Press.
Available at http://netvet.wustl.edu/species/reptiles/pough.txt
Descriptors: research and teaching, biology, physical environment, biological environment, marking, breeding, environmental conditions, medical care, health precautions for release of animals, health precautions for caretakers.

Rehg, J.E. and L.A. Toth (1998). Rodent quarantine programs: Purpose, principles, and practice. Laboratory Animal Science 48(5): 438-447.
NAL call number: 410.9 P94
Descriptors: animal health assessment, likelihood of dispersion of microorganisms of interest throughout the quarantine population during the quarantine period, interval necessary for exposed rodents to undergo seroconversion or for microorganisms to reach detectable numbers, principles of an effective program, passive vs active programs, confidence level of detection, risk of infection, cost, scientific considerations, type of caging, type of secondary enclosure, sentinel exposure method, target organisms, quarantine programs in practice, overview of program at St. Jude Children's Research Hospital, vendor specifications, sources of infection for rodents.

Secord, D.C. and H.C. Rowsell (1974). Proper use of animals in schools: An educational program. Canadian Veterinary Journal 15(2):42-47.
NAL call number: 41.8 R3224
Descriptors: biology programs, animal care, guidelines, ACUC.

Stokes, W.S. and D.J.B. Jensen (1995). Guidelines for institutional animal care and use committees: consideration of alternatives. Contemporary Topics in Laboratory Animal Science 34 (3):51-55, 58-60.
NAL call number: SF405.5.A23.
Descriptors: animal testing alternatives, committees, guidelines, information services, training, regulations.


Useful World Wide Web Sites


Institutional Animal Care and Use Committee Guidebook
http://grants.nih.gov/grants/olaw/Guide-for-the-Care-and-Use-of-Laboratory-Animals.pdf

Guide for the Care and Use of Laboratory Animals
http://www.nap.edu/openbook.php?record_id=5140

Tutorial on the PHS Policy on Humane Care and Use of Laboratory Animals
http://grants.nih.gov/grants/olaw/tutorial/index.htm

Sample Documents for Implementation of the PHS Policy on Humane Care and Use of Laboratory Animals
http://grants.nih.gov/grants/olaw/sampledoc/index.htm

National Institutes of Health Animal Research Advisory Committee Guidelines
http://oacu.od.nih.gov/ARAC/index.htm
This site includes: (1) guidelines for NIH intramural research program compliance with USDA annual reporting requirements, revised 4/09/97; (2) definitions and behavioral/clinical signs of pain; (3) guidelines on classifying deficiencies identified during semiannual reviews, revised 1/13/99; (4) guideline regarding significant changes to animal study proposals, revised 12/9/98; (5) NIH animal transportation guidelines, revised 2/10/99; (6) NIH animal transfer agreement, 2/12/97; (7) guidelines for housing animals in containment housing systems, reapproved 1/13/99; (8) NIH intramural position paper - "housing multiple species of large laboratory animals", revised 1/13/99; (9) guidelines for diet control in behavioral studies, reapproved 2/10/99 (10) Interagency Research Animal Committee (IRAC) recommendation on LD50 testing, reapproved 5/8/96 (11) NIH intramural research program - guidelines for survival rodent surgery, reapproved 2/10/99; (12) oocyte harvesting in Xenopus laevis, revised 2/10/99; (13) NIH intramural program guidelines for the prevention and control of tuberculosis in nonhuman primates, reapproved 2/10/99; (14) Interagency Research Animal Committee recommendations on toe clipping of animals, reapproved 5/8/96; (15) ascites production in mice, revised 3/11/98; (16) endpoints in animal study proposals, revised 3/8/00; (17) 1993 report of the AVMA panel on euthanasia, 1/15/93; (18) guidelines for the euthanasia of mouse and rat fetuses and neonates, revised 11/10/98; (19) minimum requirements for protective clothing in animal facilities, reapproved 2/10/99; (20) ACUC Communications, revised 11/10/98; (21) recommendations for consideration in the research use of inflammatory agents - complete Freund's adjuvant (cfa), reapproved 5/8/96; (22) guideline on pain and distress in rodents and rabbits: responsibilities, recognition and alleviation, approved 3/8/00.

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Last updated July 26, 2001