Livestock
2007
Alsop, E.J.; Marr, C.; Barrelet, A.B.; McGladdery, A.J. The use of transabdominal ultrasonography in the diagnosis and management of splenic lesions in three horses. Equine Veterinary Education. 2007; 19 (1): 5-10. ISSN: 0957-7734
URL: http://www.evj.co.uk
NAL Call Number: SF951.E67
Descriptors: horses, splenic lesions, clinical picture, Mycobacterium avium.
Benet, J.J.; Boschiroli, M.L.; Dufour, B.; Garin-Bastuji, B. Lutte contre la tuberculose bovine en
Descriptors: Mycobacterium bovis, collective control program, disease free in 2001, epidemiology, description of regulations and management, France.
Bennett, R.; Willis, K. Public opinions on badger populations and the control of tuberculosis in cattle in the
URL: http://veterinaryrecord.bvapublications.com/archive/
NAL Call Number: 41.8 V641
Descriptors: opinion survey questionnaire, prevention of bovine tuberculosis, badger management, telephone and mail survey, wildlife management sometimes necessary, role of government, opinions of population management of badgers, cost/benefit, England, Wales.
Cvetnic, Z.; Spicic, S.; Benic, M.; Katalinic-Jankovic, V.; Pate, M.; Krt, B.; Ocepek, M. Mycobacterial infection of pigs in
URL: www.akademiai.com
NAL Call Number: 41.8 AC83
Descriptors: pigs, bacterial infections, bacterioses, disease surveillance, Mycobacterium peregrinum, lymph nodes,
Flynn, Robin J.; Mannion, Celine; Golden, Olwen; Hacariz, Orcun; Mulcahy, Grace. Experimental Fasciola hepatica infection alters responses to tests used for diagnosis of bovine tuberculosis. Infection and Immunity (IAI). 2007 Mar; 75 (3): 1373-1381. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1.I57
Abstract: Fasciola hepatica is a prevalent helminth parasite of livestock. Infection results in polarization of the host's immune response and generation of type 2 helper (Th2) immune responses, which are known to be inhibitory to Th1 responses. Bovine tuberculosis (BTB) is a bacterial disease of economic and zoonotic importance. Control polices for this disease rely on extensive annual testing and a test-and-slaughter policy. The correct diagnosis of BTB relies on cell-mediated immune responses. We established a model of coinfection of F. hepatica and Mycobacterium bovis BCG to examine the impact of helminth infection on correct diagnosis. We found the predictive capacity of tests to be compromised in coinfected animals and that F. hepatica infection altered macrophage function. Interleukin-4 and gamma interferon expression in whole-blood lymphocytes restimulated in vitro with M. bovis antigen was also altered in coinfected animals. These results raise the question of whether F. hepatica infection can affect the predictive capacity of tests for the diagnosis of BTB and possibly also influence susceptibility to BTB and other bacterial diseases. Further studies on the interplay between helminth infection and BTB are warranted.
Descriptors: livestock, Fasciola hepatica, liver fluke, Mycobacterium bovis BCG, co-infection of helminths and bacteria, question whether bovine tuberculosis testing compromised, suggest further studies.
Foote, M.R.; Nonnecke, B.J.;
URL: http://jds.fass.org/cgi/content/full/90/1/404
NAL Call Number: 44.8 J822
Abstract: The objective of the study was to evaluate the effects of 3 targeted growth rates on adaptive (i.e., antigen-specific) immune responses of preruminant, milk replacer-fed calves. Calves (9.1 +/- 2.4 d of age) were assigned randomly to one of 3 dietary treatments to achieve 3 targeted daily rates of gain [no growth (maintenance) = 0.0 kg/d, low growth = 0.55 kg/d, or high growth = 1.2 kg/d] over an 8-wk period. The NRC Nutrient Requirements of Dairy Cattle calf model computer program was used to estimate the milk replacer intakes needed to achieve target growth rates. All calves were fed a 30% crude protein, 20% fat, all-milk protein milk replacer reconstituted to 14% dry matter. Diets were formulated to ensure that protein would not be limiting. All calves were vaccinated 3 wk after initiation of dietary treatments with Mycobacterium bovis, strain bacillus Calmette-Guerin and ovalbumin. Growth rates for no-growth (0.11 kg/d), low-growth (0.58 kg/d), and high-growth (1.16 kg/d) calves differed throughout the experimental period. Blood glucose concentrations in high-growth calves increased with time and were higher than in low- and no-growth calves. Mononuclear and polymorphonuclear leukocyte percentages in peripheral blood were unaffected by growth rate but did change with advancing age. Percentages of CD4(+) T cells increased with age in no-growth and low-growth calves, a characteristic of maturation, but failed to increase in high-growth calves. Growth rate did not affect the percentages of CD45RO(+) (memory) CD4(+) and CD8(+) T cells, antigen (i.e., ovalbumin)-specific serum IgG concentrations, or antigen (i.e., purified protein derivative)-induced IFN-gamma and nitric oxide secretion by mononuclear cell cultures. Antigen-elicited cutaneous delayed-type hypersensitivity responses of no-growth calves exceeded responses of low-growth, but not high-growth, calves. In resting- and antigen-stimulated cell cultures, viabilities of CD4(+), CD8(+), and gamma delta TCR+ T cells from high-growth calves were lower than those of the same T cell subsets from no-growth and low-growth calves. Alternatively, resting cultures of mononuclear leukocytes from high-growth calves produced more nitric oxide than those from no-growth and low-growth calves. In conclusion, adaptive immune responses were affected minimally by growth rate. The results suggest that protein-energy malnutrition in the absence of weight loss is not detrimental to antigen-specific responses of neonatal vaccinated calves and that a high growth rate does not enhance these responses. The negative effect of a high growth rate on the viability of circulating T cell populations may influence infectious disease resistance of the calf.
Descriptors: neonates, cattle disease, Mycobacterium bovis, serum, immune system, CD8+ T-cell, CD4+ T cell, adaptive immunity, growth rates.
Gumussoy, vK.S.; Atasever, A.; Aydn, F.; Ozcan, M.; Beyaz, L.; Hzlsoy, H.; Abay, S. Prevalence of tuberculosis in cattle in Turkey. Medycyna Weterynaryjna. 2007; 63 (3): 305-308. ISSN: 0025-8628. Note: In English with a Polish summary.
URL: http://www.medwet.lublin.pl
NAL Call Number: 41.8 M463
Descriptors: cattle, disease prevalence, bovine tuberculosis, Mycobacterium bovis, tissues from slaughtered cattle, 5 abattoirs, lungs, bronchi, mediastinal lymph nodes, BACTEC radiometric method was a rapid and sensitive diagnostic method, Kayseri province, Turkey.
Johnson, L.; Dean, G.; Rhodes, S.; Hewinson, G.; Vordermeier, M.; Wangoo, A. Low-dose Mycobacterium bovis infection in cattle results in pathology indistinguishable from that of high-dose infection. Tuberculosis. 2007; 87 (1): 71-76. ISSN: 1472-9792
URL: http://www.sciencedirect.com/science/journal/14729792
Descriptors: cattle, experimental infection, Mycobacterium bovis field strain (AF2122/97) effects of low and high doses of colony forming units, immunohistochemistry, lesion advancement and granuloma distribution, IFN gamma expression, 24 week study, no difference in infection between high and low dosages.
Jolley, M.E.; Nasir, M.S.; Surujballi, O.P.; Romanowska, A.; Renteria, T.B.; Mora, A. de la; Lim, A.; Bolin, S.R.; Michel, A.L.; Kostovic, M.; Corrigan, E.C. Fluorescence polarization assay for the detection of antibodies to Mycobacterium bovis in bovine sera. Veterinary Microbiology. 2007; 120 (1/2): 113-121. ISSN: 0378-1135
URL: http://www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: The performance of a fluorescence polarization assay (FPA) that detects antibodies to Mycobacterium bovis in bovine sera is described. The FPA reported here is a direct binding primary screening assay using a small polypeptide derived from the M. bovis MPB70 protein. A secondary inhibition assay confirms suspect or presumed positive samples. Specificity studies involved five different veterinary laboratories testing 4461 presumed negative bovine samples. FPA specificity was 99.9%. The FPA was used to identify herd status as either M. bovis infected or non-infected. Herd surveillance studies (nine herds) were performed in Mexico and South Africa. The FPA had a specificity of 100% (two negative herds), and correctly identified six of seven infected herds. Finally, sera from 105 slaughter animals that had gross lesions in lymph nodes similar to those seen with bovine tuberculosis were tested by the FPA. Thin sections from the associated formalin-fixed paraffin-embedded samples of lymph nodes were stained using hematoxylin and eosin (H&E) for morphologic examination and using the Ziehl-Neelsen (ZN) method for detection of acid-fast bacilli. Of the 105 animals, 78 were classified as TB suspect based on lesion morphology, 21 were positive by ZN, 9 were positive by FPA and 13 were positive by PCR for the tuberculosis group of Mycobacterium. Among the 21 ZN positives, 11 (52.4%) were PCR positive. Among the 9 FPA positives, 8 (88.9%) were PCR positive. For the 13 PCR positives, 8 (61.5%) were FPA positive and 11 (84.6%) were ZN positives. These results show that use of the FPA for detection of M. bovis infection of cattle has value for bovine disease surveillance programs.
Descriptors: cattle, Mycobacterium bovis, disease surveillance, serological diagnosis, serological techniques, Mexico, South Africa.
Komijn, R.E.; Wisselink, H.J.; Rijsman, V.M.C.; Stockhofe-Zurwieden, N.; Bakker, D.; Zijderveld, F.G. van; Eger, T.; Wagenaar, J.A.; Putirulan, F.F.; Urlings, B.A. Granulomatous lesions in lymph nodes of slaughter pigs bacteriologically negative for Mycobacterium avium subsp. avium and positive for Rhodococcus equi. Veterinary Microbiology. 2007; 120 (3/4): 352-357. ISSN: 0378-1135
URL: http://www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: The prevalence of granulomatous lesions in lymph nodes of pigs was studied. From January till August 2004 in two slaughterhouses in The Netherlands 2 116 536 pigs were examined for the presence of granulomatous lesions in the sub-maxillary lymph nodes. In 15 900 (0.75%) of these pigs, lesions could be detected. Nine farms with the highest incidence of lesions were selected for a more detailed pathological and bacteriological examination. On these farms, the prevalence of lesions in sub-maxillary lymph nodes ranged from 2.3 to 5.7% with a mean of 3.0%. From 1276 pigs that were sampled, 98 (7.7%) displayed granulomatous lesions in the sub-maxillary lymph nodes and one (0.1%) pig showed lesions in its mesenteric lymph node. Mycobacterium avium subsp. avium (MAA) could not be isolated from the lymph nodes of the 99 pigs with lesions and from a selection of lymph nodes (n=61) of pigs without lesions. Rhodococcus equi was isolated from 44 out of 98 (44.9%) of the sub-maxillary lymph nodes with granulomatous lesions and from two mesenteric lymph nodes without lesions. A comparison of former studies and the current results indicate that the prevalence of MAA infections in slaughter pigs has strongly decreased over the last decade, whereas R. equi is highly prevalent. The high incidence of granulomatous lesions associated with the bacteriological presence of R. equi could be considered as a serious cause of misdiagnosis of MAA infections in cases where meat inspection is carried out by inspection for granulomatous changes of lymph nodes only..
Descriptors: pigs, Mycobacterium avium, Rhodococcus equi, disease surveillance, slaughter house survey, The Netherlands.
Liu, Siguo; Guo, She Ping; Wang, Chun Lai; Shao, Mei Li; Zhang, Xiu Hua; Guo, Yang; Gong, Qiang. A novel fusion protein-based indirect enzyme-linked immunosorbent assay for the detection of bovine tuberculosis. Tuberculosis (Amsterdam). 2007; 87 (3): 212-217. ISSN: 1472-9792
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/638428/description?navopenmenu=-2
Descriptors: ELISA; serodiagnosis of Mycobacterium bovis; antigen genes, mpb70, mpb83, and esat-6; spliced overlap extension technology; expressed in Escherichia coli; fusion protein (rM7083-E6); serum testing of cattle; sensitivity and specificity.
Marsh, I.B.; Whittington, R.J. Genomic diversity in Mycobacterium avium: Single nucleotide polymorphisms between the S and C strains of M-avium subsp paratuberculosis and with M-a. avium. Molecular and Cellular Probes. 2007; 21 (1): 66-75. ISSN: 0890-8508
URL: http://www.sciencedirect.com/science/journal/08908508
Descriptors: sheep; cattle; Mycobacterium avium paratuberculosis; strain C; strain S; Mycobacterium avium avium; amino acid sequence; nucleotide sequence; genomic diversity; species comparison; GenBank sequence numbers; 12,117 bp of sequence representing 26 loci across 25 genes; 11 SNPs were identified between the S and C strains in eight genes: hsp65, sodA, dnaA, dnaN, recF, gyrB, inhA, and pks8.
Meikle, V.; Schneider, M.; Azenzo, G.; Zumarraga, M.; Magnano, G.; Cataldi, A. Individual animals of a cattle herd infected with the same Mycobacterium bovis genotype shows important variations in bacteriological, histopathological and immune response parameters. Zoonoses and Public Health. 2007; 54 (2): 86-93. ISSN: 1863-1959
Descriptors: Friesian cattle, Mycobacterium bovis, tuberculin test, slaughterhouse surveillance, diagnostic tests comparison study, interferon gamma, PCR, bacteriological culture of nasal swab and intradermal tuberculin test, clinical parameter, tuberculosis lesions, spoligotyping, several tests recommended.
Montgomery, A. Incidence and sensitivity of major bovine respiratory disease pathogens in Europe. Veterinary Times. 2007; 37 (2): 24. ISSN: 1352-9374
Descriptors: cattle, acute signs of bovine respiratory disease, sampling with swabs, 220 pathogens isolated, Arcanobacterium pyogenes, Histophilus, Mycobacterium bovis, Pasteurella haemolytica, Pasteurella multocida, sensitivity to antiobiotics, florfenicol, tilmicosin, tulathromycin, tetracycline, 8 European countries.
Mores, Nelson; Ventura, Lauren; Dutra, Valeria; Silva, Virginia S.; Barioni, Waldomiro Jr; Oliveira, Salete R.; Kramer, Beatris.; Neto, Jose S. Ferreira. Granulomatous lymphadenitis in swine: lymph nodes affected and pathologic diagnosis of the infection caused by Mycobacterium avium complex agents. Pesquisa Veterinaria Brasileira. 2007; 27 (1): 13-17. ISSN: 0100-736X. Note: In Portuguese.
URL: http://www.scielo.br/scielo.php?script=sci_issues&pid=0100-736X&lng=en&nrm=iso
NAL Call Number: SF756.37.B7 P5
Descriptors: 394 swine carcasses from cold storage, Service of Federal Inspection, pigs, granulomatous lesions, lymph nodes, histopathology, Ziehl-Neelsen staining, histopathological examination, immunohistochemistry with monoclonal antibody produced with cellular extract of M. avium, comparison of tests, Brazil.
Mukherjee, F. Comparative prevalence of tuberculosis in two dairy herds in India. Revue Scientifique et Technique Office International des Epizooties. 2006; 25 (3): 1125-1130. ISSN: 0253-1933. Note: In English with summaries in Spanish and French.
Abstract: Holstein Friesian cows and their crossbred progeny on a farm in northern India were tested for tuberculosis (TB) infection using a single intradermal tuberculin test. The results showed that the animals persistently harboured TB infection for periods of two to four years. The recent comparative intradermal tuberculin test revealed that at least five out of nine of these cattle reacted positively to bovine tuberculin purified protein derivative. A high (15.76%) prevalence rate resulted because none of the infected animals had been segregated or culled from the herd since the first incidence was detected in 1992. In contrast, another farm in western India that practiced segregation and culling was able to contain the level of prevalence of TB between 0.65% and 1.85%. These findings call for stricter regulations on the management of TB at farm, state and country level and a revision in the mode of breeding programmes adopted by farms..
Descriptors: cattle, disease control programs, effects of segregation and culling of TB infected cows, Mycobacterium bovis, India.
Ozygt, M.O.; Senturk, S.; Akkoc, A. Suspected congenital generalised tuberculosis in a newborn calf. Veterinary Record. 2007; 160 (9): 307-308. ISSN: 0042-4900
URL: http://veterinaryrecord.bvapublications.com/archive/
NAL Call Number: 41.8 V641
Descriptors: cattle, newborn calf, Mycobacterium bovis, case report, clinical picture, postmortem examination, congenital disease, Turkey.
Porphyre, Thibaud; McKenzie, Joanna; Stevenson, Mark. A descriptive spatial analysis of bovine tuberculosis in intensively controlled cattle farms in New Zealand. Veterinary Research (Les-Ulis). 2007; 38 (3): 465-479. ISSN: 0928-4249
URL: http://www.vetres.org/
NAL Call Number: SF602.A5
Descriptors: cattle, bovine tuberculosis, Mycobacterium bovis, 69 farms, poisoning for depopulating area of brushtail possum (Trichosurus vulpecula), wildlife disease reservoir, disease transmission from possums, North Island, New Zealand.
Raj, G.D.; Mathivanan, B.; Matheswaran, K.; Nachimuthu, K.; Davis, W.C. Lymphocyte subset distribution in apparently normal and single intradermal test-positive water buffaloes analyzed by flow cytometry. Research in Veterinary Science. 2007; 82 (1): 34-38.
URL: http://www.sciencedirect.com/science/journal/00345288
Descriptors: water buffalo, lymphocytes, antibodies, CD3+ lymphocytes, CD8+ cells, histocompatibility complex, peripheral blood, T cells, T4 lymphocytes, mononuclear cells, single intradermal test, Mycobacterium bovis.
Seward, Nathan W.; Phillips, Gregory E.; Duquette, Jared F.; Vercauteren, Kurt C. A frightening device for deterring deer use of cattle feeders. Journal of Wildlife Management. 2007; 71 (1): 271-276. ISSN: 0022-541X
URL: http://www.bioone.org/perlserv/?request=get-archive&issn=0022-541X&ct=1
NAL Call Number: 410 J827
Abstract: The presence of bovine tuberculosis (TB) in cattle can negatively impact a state's economy and cattle industry. In Michigan, USA, wild white-tailed deer (Odocoileus virginianus) are a reservoir for reinfecting cattle herds. Although direct TB transmission between deer and cattle is rare, infected deer may contaminate cattle feed. To mitigate this risk, we designed and evaluated a deer-resistant cattle feeder (DRCF) device for deterring deer from feeders. The device delivered negative stimuli to condition deer to avoid cattle feeders. We tested the device by conducting a comparative change experiment at a high-density captive white-tailed deer operation in northeastern lower Michigan using pretreatment and treatment periods and random allocation of DRCF protection to 3 of 6 feeders during the treatment period. We used animal-activated cameras to collect data on deer use of feeders. Deer use was similar at protected and unprotected feeders during the pretreatment period but was lower at protected feeders during the treatment period. Deer-resistant cattle feeders were 100% effective during the first 2 treatment weeks, 94% during the first 5 weeks, but effectiveness then dropped to 61% during the final week. Excluding problems associated with low battery power and infrared sensors, DRCFs were 99% effective at deterring deer. Our results suggest that DRCFs can effectively limit deer use of cattle feed, potentially with minimal impact on feeding behavior of cattle, thus reducing potential transmission of bovine TB through contaminated feed. By employing DRCFs in bovine TB endemic areas, especially at times that deer are food stressed, agencies and producers can practically and economically reduce the potential for bovine TB to be transmitted from deer to cattle.
Descriptors: white-tailed deer, (Odocoileus virginianus), feeding patterns, negative stimulus deer resistant cattle feeder, long term effectiveness, feeding stations, disease transmission between species, Mycobacterium bovis, wild vs captive deer operation, Michigan, US.
Smith, G.C.; Bennett, R.; Wilkinson, D.; Cooke, R. A cost-benefit analysis of culling badgers to control bovine tuberculosis. Veterinary Journal. 2007; 173 (2): 302-310. ISSN: 1090-0233
URL: http://www.sciencedirect.com/science/journal/10900233
Descriptors: cattle, herds, badgers (Meles meles), simulated culling strategies, badger trapping and gassing, disease control strategy Mycobacterium bovis, disease transmission, UK Government's Department for Environment Food and Rural Affairs (Defra), UK.
Twomey, D.F.; Crawshaw, T.R.; Anscombe, J.E.; Farrant,.L.; Evans, L.J.; McElligott, W.S.; Higgins, R.J.; Dean, G.; Vordermeier, M.; Jahans, K.; Rua-Domenech, R. de la. TB in llamas caused by Mycobacterium bovis. Veterinary Record. 2007; 160 (5): 170. ISSN: 0042-4900
URL: http://veterinaryrecord.bvapublications.com/archive/
NAL Call Number: 41.8 V641
Descriptors: llama herd, diagnosis of tuberculosis, Mycobacterium bovis, seroprevalence, tests for antibodies, intradermal tuberculin test, Devon, UK.
Vega-Manriquez, X.; Lopez-Vidal, Y.; Moran, J.; Adams, L.G.; Gutierrez-Pabello, J.A. Apoptosis-inducing factor participation in bovine macrophage Mycobacterium bovis-induced caspase-independent cell death. Infection and Immunity. 2007; 75 (3): 1223-1228. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1. I57
Abstract: Mycobacterium tuberculosis complex species survive and replicate in phagosomes of the host cell. Cell death (CD) has been highlighted as one of the probable outcomes in this host-pathogen interaction. Previously, our group demonstrated macrophage apoptosis as a consequence of Mycobacterium bovis infection. In this study, we aimed to identify the contribution of apoptotic effector elements in M. bovis-induced CD. Bovine macrophages were either infected with M. bovis (multiplicity of infection, 10:1) or treated with an M. bovis cell extract (CFE). Structural changes compatible with CD were evaluated. Chromatin condensation was increased three times by the CFE. On the other hand, a terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) assay demonstrated that levels of DNA fragmentation induced by M. bovis and CFE were 53.7%+or-24% and 38.9%+or-14%, respectively, whereas control cells had a basal proportion of 8.9%+or-4.1%. Rates of DNA fragmentation were unaffected by the presence of the pan-caspase inhibitor N-benzyloxycarbonyl-Val-Ala-Asp (z-VAD). Cells treated with 100 micro g of CFE for 12 h had a fivefold decrease in the level of mitochondrial outer membrane permeabilization compared to that of untreated cells. Neither M. bovis infection nor CFE treatment induced activation of caspase 3, 8, or 9. Translocation of apoptosis-inducing factor (AIF) to the nucleus was identified in 32%+or-3.5% and 26.3%+or-4.9% of M. bovis-infected and CFE-treated cells, respectively. Incubation of macrophages with z-VAD prior to infection did not alter the percentage of cells showing AIF translocation. Our data suggest that M. bovis-induced CD in bovine macrophages is caspase independent with AIF participation.
Descriptors: bovine macrophages, Mycobacterium bovis, caspase.
Waters, W.R.; Nonnecke, B.J.; Olsen, S.C.; Palmer, M.V. Effects of pre-culture holding time and temperature on interferon- gamma responses in whole blood cultures from Mycobacterium bovis-infected cattle. Veterinary Microbiology. 2007; 119 (2/4): 277-282. ISSN: 0378-1135
URL: http://www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: The BovigamTM assay is approved for use within the United States as a complementary tuberculosis test. Prior to whole blood culture and the ensuing ELISA to detect interferon-(IFN)- gamma, samples are subjected to various holding time/temperature combinations due, in part, to practical constraints associated with shipment of samples to approved laboratories. To evaluate these effects, 5-month-old Holstein calves (n=7) received 103 cfu Mycobacterium bovis by aerosol. Heparinized blood was collected 2 months after challenge and held at 4 or 22 degrees C for 0, 8 or 24 h prior to culture with mycobacterial antigens or pokeweed mitogen (PWM). Responses of samples held for 8 or 24 h were comparable and lower than responses of cultures prepared immediately after collection, regardless of holding temperature. Differences in responses of samples held at 4 degrees C versus 22 degrees C were also minimal. A subset of samples was held for 2 h at 37 degrees C at the beginning of the holding period. This subset of samples had diminished responses to all stimulants and increased holding times (i.e., 24 h versus 8 h) negatively impacted the response. Pre-processing conditions, particularly delays in set-up and initial high sample temperatures, reduces IFN-gamma responses of cells from infected cattle increasing the risk of false negatives in this assay of regulatory importance.
Descriptors: young Holstein cattle, experimental infection, aerosol exposure to Mycobacterium bovis, blood analysis, ELISA, assays, IFN-gamma responses, immunological reactions.
Westhusin, M.E.; Shin, T.; Templeton, J.W.; Burghardt, R.C.; Adams, L.G. Rescuing valuable genomes by animal cloning: a case for natural disease resistance in cattle. Journal of Animal Science. 2007; 85 (1): 138-142. ISSN: 0021-8812
URL: http://www.asas.org
NAL Call Number: 49 J82
Abstract: Tissue banking and animal cloning represent a powerful tool for conserving and regenerating valuable animal genomes. Here we report an example involving cattle and the rescue of a genome affording natural disease resistance. During the course of a 2-decade study involving the phenotypic and genotypic analysis for the functional and genetic basis of natural disease resistance against bovine brucellosis, a foundation sire was identified and confirmed to be genetically resistant to Brucella abortus. This unique animal was utilized extensively in numerous animal breeding studies to further characterize the genetic basis for natural disease resistance. The bull died in 1996 of natural causes, and no semen was available for AI, resulting in the loss of this valuable genome. Fibroblast cell lines had been established in 1985, cryopreserved, and stored in liquid nitrogen for future genetic analysis. Therefore, we decided to utilize these cells for somatic cell nuclear transfer to attempt the production of a cloned bull and salvage this valuable genotype. Embryos were produced by somatic cell nuclear transfer and transferred to 20 recipient cows, 10 of which became pregnant as determined by ultrasound at d 40 of gestation. One calf survived to term. At present, the cloned bull is 4.5 yr old and appears completely normal as determined by physical examination and blood chemistry. Furthermore, in vitro assays performed to date indicate this bull is naturally resistant to B. abortus, Mycobacterium bovis, and Salmonella typhimurium, as was the original genetic donor.
Descriptors: cattle, Brucella abortus, Mycobacterium bovis, Salmonella typhimurium, nuclear transfer, cloned animal, resistance to disease as a genetic trait.
Witchell, J.; Vordermeier, M.; Wangoo, A.; Goyal, M. Cytokine mRNA expression levels within BCG vaccinated and non-vaccinated, Mycobacterium bovis challenged cattle. Immunology. 2007; 120(Suppl. 1): 69. ISSN: 0019-2805. Note: Annual Congress of the British Society of Immunology, Glasgow, UK; February 20-23, 2007.
URL: http://www3.interscience.wiley.com/journal/118493028/home?cookieSet=1
Descriptors: cattle, Mycobacterium bovis, pathogen, lymph nodes, blood and lymphatics, T-helper-type 1 cells,
Xu, Guang Xian; Zhao, De Ming; Zhou, Xiang Mei; Yin, Xiao Min; Yang, Jian Min Expression of TNF- alpha , iNO, IL-6, and IL-12 in alveolar macrophage contribution by Mce4E protein of Mycobacterium bovis. Journal of China Agricultural University. 2007; 12 (1): 1-6. ISSN: 1007-4333. Note: In Chinese with an English summary.
NAL Call Number: S19.C58
Descriptors: livestock infection, cell entry proteins, alveolar macrophage, exposure to M. bovis, expression of TNF-alpha, iNO, IL-6 and IL-12, cachectin, cachexin, immunity reactions, immunological reactions, PCR real time, tumor necrosis factor
2006
Aagaard, C.; Govaerts, M.; Meikle, V.; Vallecillo, A.J.; Gutierrez-Pabello, J.A.; Suarez-Guemes, F.; McNair, J.; Cataldi, A.; Espitia, C.; Andersen, P.; Pollock, J.M. Optimizing antigen cocktails for detection of Mycobacterium bovis in herds with different prevalences of bovine tuberculosis: ESAT6-CFP10 mixture shows optimal sensitivity and specificity. Journal of Clinical Microbiology (JCM). 2006 Dec; 44 (12): 4326-4335. ISSN: 0095-1137
URL: http://jcm.asm.org/
NAL Call Number: QR46 .J6
Abstract: Bovine tuberculosis is a major problem in many countries; hence, new and better diagnostic tools are urgently needed. In this work, we have tested ESAT6, CFP10, PE13, PE5, MPB70, TB10.4, and TB27.4 for their potentials as diagnostic markers in field animals from Northern Ireland, Mexico, and Argentina, regions with low, medium, and high prevalences of bovine tuberculosis, respectively. At all three sites, ESAT6 and CFP10 were superior diagnostic antigens, while their combination performed even better at the two sites where the combination was tested, providing the best coverage for the detection of diseased populations. The high sensitivity in the skin test reactor groups, combined with the high specificity in the tuberculosis-free groups, indicated that a diagnosis could correctly be made for 85% of the infected animals, based on their responses to these two antigens. Furthermore, TB10.4, PE13, and PE5 have the potential to supplement ESAT6 and CFP10 in a future five-component diagnostic cocktail.
Descriptors: cattle, Mycobacterium bovis, diagnostic tools, diagnostic markers, strains from over the world, ESAT6, CFP10 superior antigens, TB10.4, PE13, and PE5.
Abernethy, D.A.; Denny, G.O.; Menzies, F.D.; McGuckian, P.; Honhold, N.; Roberts, A.R. The Northern Ireland programme for the control and eradication of Mycobacterium bovis. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 231-237. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Abstract: Bovine tuberculosis is endemic in Northern Ireland and a comprehensive eradication scheme has been in operation since 1959. The current programme involves annual testing, extensive computerized tracing, short-interval testing of herds contiguous to outbreaks and compulsory slaughter of positive cattle. Despite initial reductions in disease prevalence, eradication has proved elusive and potential explanatory factors include high cattle density and potential for between-herd contact, the impact of exotic diseases on resource priorities, and significant levels of bovine tuberculosis in a wildlife reservoir, the European badger (Meles meles). Both the role of the infected bovine and that of the badger in spreading disease have to be addressed to ensure progress towards eradication. Current measures are described and future options for enhancing the programme are outlined.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, disease control, disease control programs, disease surveillance, disease outbreaks, culling animals, herd health, stocking rate, wildlife, disease reservoirs, disease transmission, risk assessment, disease eradication, Northern Ireland.
Ahmed, J. Transboundary diseases. Proceedings of the International Conference on the Impact of Endemic and Epidemic Diseases on National, Regional and International Trade, Istanbul, Turkey, February 2006. Journal of Veterinary Medicine Series B. 2006; 53 (Suppl. 1): 1-42. ISSN: 0931-1793. Note: 13 papers,
URL: http://www3.interscience.wiley.com/journal/120118373/tocgroup
Descriptors: birds, cattle, transboundry disease, Brucella, foot and mouth disease virus, FMD, Mycobacterium bovis, peste des petits ruminants virus, avian influenza virus, bird flu, bird grippe, cattle plague, disease surveillance, seroepidemiology, poverty-alleviation, EC, EEC, European Communities, European Economic Communities, China, Pakistan, Iran, Iraq, Turkey.
Ahmed, J. Transboundary diseases. Proceedings of the International Conference on the Impact of Endemic and Epidemic Diseases on National, Regional and International Trade, Istanbul, Turkey, February 2006. Journal of Veterinary Medicine Series B. 2006; 53 (Suppl. 1): 1-42. ISSN: 0931-1793. Note: 13 papers,
URL: http://www.blackwell-synergy.com/toc/jvb/53/s1
Descriptors: birds, cattle, diseases that cross political boundries, Brucella, foot and mouth disease virus, FMD, Mycobacterium bovis, peste des petits ruminants virus, avian influenzavirus, bird flu, bird grippe, cattle plague, disease surveillance, seroepidemiology, poverty alleviation, EC, EEC, European Economic Communities, China, Pakistan, Iran, Iraq, Turkey.
Allison, N. Mycobacterium avium infection in a dog. Veterinary Medicine. 2006 Jan; 101 (1): 14. ISSN: 8750-7943
NAL Call Number: 41.8 M69
Descriptors: dogs, Mycobacterium avium, case studies.
Almeida, Robson F.C.; Madruga, Claudio R.; Soares, Cleber O.; Fernandes, Marta C.; Carvalho, Nilton M.; Jorge, Klaudia S.G.; Osorio, Ana Luiza A.R. Resposta imune especifica de bovinos experimentalmente sensibilizados com inoculos inativados de Mycobacterium bovis e Mycobacterium avium. [Specific immune response of cattle to experimental sensibilization by inactivated Mycobacterium bovis and Mycobaceterium avium.] Pesquisa Veterinaria Brasileira. 2006; 26(4): 195-200. ISSN: Note: In Portuguese.
URL: http://www.scielo.br/scielo.php?script=sci_issues&pid=0100-736X&lng=en&nrm=iso
NAL Call Number: SF756.37.B7 P5
Descriptors: cattle, Mycobacterium bovis, Mycobacterium avium, bacterial pathogens, diagnosis via immune response, bacterial antigens, cervical comparative test, evolution of the specific production of gamma-interferon,identification of interference of unspecified reactions by M. avium, test results.
Amanfu, William. The situation of tuberculosis and tuberculosis control in animals of economic interest. Tuberculosis (Amsterdam). 2006; 86 (3-4): 330-335. ISSN: 1472-9792
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/638428/description?navopenmenu=-2
Descriptors: animals, tuberculosis, Mycobacterium bovis, public health concerns, veterinary medicine concern, incidence in humans, concerns for disease control in developed and developing countries.
Amaral, A.L. do; Mores, N.; Ventura, L. das V.; Coldebella, A.; Ludke, J.V.; Oliveira, P.A.V. de; Silva, V.S. Ocorrencia de linfadenite em suinos criados em sistema convencional e cama sobreposta nas fases de crescimento e terminacao. [Occurrence of lymphadenitis in swine created in conventional and deep-litter system at the growth-termination phase.] Revista de Ciencias Agroveterinarias. 2006; 5 (1): 64-72. ISSN: 1676-9732. Note: In Portuguese with an English summary.
URL: http://www.cav.udesc.br
Descriptors: pigs; swine housing; piggeries, litter systems compared: T1 deep-litter of wood shaving, T2 deep-litter of rice husk and T3 partially slatted floor; Mycobacterium avium complex; animal pathogens; granulomatous lymphadenitis; feces; liveweight gains.
Aranaz, Alicia; De Juan, Lucia; Bezos, Javier; Alvarez, Julio; Romero, Beatriz; Lozano, Francisco; Paramio, Jose L; Lopez-Sanchez, Jesus; Mateos, Ana; Dominguez, Lucas. Assessment of diagnostic tools for eradication of bovine tuberculosis in cattle co-infected with Mycobacterium bovis and M-avium subsp. paratuberculosis. Veterinary Research (Les Ulis). 2006; 37(4): 593-606. ISSN: 0928-4249
URL: http://www.vetres.org/
NAL Call Number: SF602.A5
Descriptors: Mycobacterium bovis, bovine tuberculosis, Mycobacterium avium ssp. paratuberculosis, dual infected cattle herd, diagnostic tests, field trial, serial parallel testing, comparative IDTB test, IFN-gamma assay, serology of paratuberculosis, detection levels, possible jcross reactivity, need for several diagnostic techniques.
Bannalikar, A.S.; Rishendra Verma. Characterization of Mycobacterium fortuitum isolates from animals and their environment by PCR-RFLP analysis (PRA) of hsp65 and rpoB genes. Indian Journal of Animal Sciences. 2006; 76 (2): 109-113. ISSN: 0367-8318
NAL Call Number: 41.8 IN22
Descriptors: Mycobacterium fortuitum I and II, isolates of soil, water, animal tissue, biochemical testing, Mycobacterium fortuitum, amplification generated a 439 bp product, RFLP patterns, BSTEII digests, HaeIII digests, MspI digestion, species and subspecies identification.
Barlow, A.M.; Monies, R.J. Bovine tuberculosis in pigs in Cornwall and the west of England. Pig Journal. 2006; 58: 204-211
URL: http://www.thepigsite.com/pigjournal/
Descriptors: badgers, cattle, pigs, historical pattern of mycobacterial infection, wild and domestic pigs, environmental contamination, Mycobacterium avium from infected birds, Mycobacterium bovis from scavenged dead carcasses or feed and water, ingestion of contaminated milk or milk products, interaction with badgers is a risk, UK
Bennett, R.M.; Cooke, R.J. Costs to farmers of a tuberculosis breakdown. Veterinary Record. 2006 Apr. 1; 158 (13): 429-432. ISSN: 0042-4900
URL: http://veterinaryrecord.bvapublications.com/
NAL Call Number: 41.8 V641
Descriptors: cattle, bovine tuberculosis, Mycobacterium bovis, disease outbreaks, costs and returns, England.
Beran, V.; Matlova, L.; Horvathova, A.; Bartos, M.; Moravkova, M.; Pavlik, I. Mycobacteria in the animal's environment in the Czech Republic. Veterinarski Arhiv. 2006; 76(Supplement): S33-S39. ISSN: 0372-5480
URL: http://www.vef.hr/vetarhiv
NAL Call Number: 41.8 V6416
Descriptors: farm and captive wild animals, environmental mycobacteria, breeding facilities, tanks, fish aquaria, peat as feed supplement, 1389 samples, 29 sites, bacteria cultured, Stonebrink's medium, Herrold's egg yolk medium, Sula's medium, Mycobacterium avium, Mycobacterium fortuitum, Mycobacterium gordonae, Mycobacterium marinum, Mycobacterium flavescens, zoonotic infections, Czech Republic.
Blissitt, M.J. The introduction of pre and post-movement TB testing in Scotland for cattle from high incidence TB areas. GVJ-Government Veterinary Journal. 2006; 16 (1): 58-64. ISSN: 0269-5545
URL: http://www.defra.gov.uk/animalh/gvj/default.htm
Descriptors: cattle, high levels of Mycobacterium bovis, zoonotic diseases, testing for disease, control programs, Scotland, Britain, UK.
Brook, R.K.; McLachlan, S.M. Factors influencing farmers' concerns regarding bovine tuberculosis in wildlife and livestock around Riding Mountain National Park. Journal of Environmental Management. 2006; 80 (2): 156-166. ISSN: 0301-4797
URL: http://www.sciencedirect.com/science/journal/03014797
NAL Call Number: HC75.E5J6
Abstract: Despite intensive efforts over the last century to eradicate bovine tuberculosis (TB) in North America, several hotspots of infected wildlife and livestock remain, raising concerns that the disease will never be eradicated. The stress and frustration for a farmer caused by having a herd test positive for TB or living in an infected region can be substantial. The goal of this study was to investigate the concerns of farmers around Riding Mountain National Park (RMNP) regarding the presence of TB in wildlife and livestock and conduct an exploratory analysis of causal factors. Data were collected from 786 farmers within 50 km of RMNP using a mail-back questionnaire. Overall, farmers indicated a high level of concern toward diseases in both wildlife and cattle relative to other concerns. The spatial variables that had the greatest influence on TB concern were both the distance of farms to the RMNP boundary and distance of farms to previous cases of TB. The most important aspatial factor associated with high TB concern was the frequency with which farmers observed elk on their land. These results underscore the important differences between 'objective' measures of risk, such as epidemiological estimates of disease prevalence, and subjective measures of disease concern, such as risk perception and acceptability of management actions. Written responses suggest that concerns regarding disease may affect how farmers view wildlife on their land and their relationship with neighbouring protected areas. Management activities that reduce the frequency of elk interactions with farms, but also recognize the complex relationship that farmers have with wildlife and protected areas, will be most effective in mitigating farmer concern regarding this important problem.
Descriptors: cattle, elk, wildlife disease reservoirs, disease control programs, bovine tuberculosis, farmers/ranchers concerns, disease risks, private and protected lands, Canada.
Bourne, F.J.; Donnelly, C.A.; Cox, D.R.; Gettinby, G.; McInerney, J.P.; Morrison, W.I.; Woodroffe, R. TB policy and the badger culling trials. Veterinary Record (London). 2006; 158 (19): 671-672. ISSN: 0042-4900
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: badgers, cattle, Mycobacterium bovis, wildlife as disease reservoir, culling badgers, disease control policies.
Bourne, F.J.; Donnelly, C.A.; Cox, D.R.; Gettinby, G.; McInerney, J.P.; Morrison, W.I.; Woodroffe, R. TB policy and the badger culling trials. Veterinary Record (London). 2006; 158 (12): 418. ISSN: 0042-4900
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: cattle, badgers (Meles meles), wildlife reservoir for Mycobacterium bovis, UK.
Bowen-Davies, J. Mycobacterium bovis in British deer. Deer Farming. 2006; (82): 17-21.
Descriptors: deer, Mycobacterium bovis, zoonotic infection, active disease surveillance, immunity reactions, lack of diagnostic tests, clinical picture, Capreolus capreolus, red deer (Cervus elaphus), fallow deer (Dama dama), Muntiacus, Mycobacterium bovis, Britain.
Buddle, B.M.; Wedlock, D.N.; Denis, M. Progress in the development of tuberculosis vaccines for cattle and wildlife. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4) 191-200. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: Vaccination against bovine tuberculosis is likely to become an important disease control strategy in developing countries, which cannot afford a test and slaughter control programme, or in countries which have a wildlife reservoir of Mycobacterium bovis infection. In the past decade, considerable progress has been made in the development and evaluation of tuberculosis vaccines for cattle and for a range of wildlife maintenance hosts including possums, badgers, deer and African buffaloes. Experimental challenge systems have been established for the different target species and the resulting disease process has mimicked that seen in the field. In cattle, neonatal vaccination with BCG appeared to be more effective than vaccination of 6-month-old calves and in most situations no other vaccine has been shown to be better than BCG. However, prime-boost strategies involving combinations of BCG with a protein or DNA vaccine, to improve on BCG vaccination alone, have produced very encouraging results. Differential diagnostic tests have been developed using mycobacterial antigens that are only present in virulent M. bovis to differentiate between BCG-vaccinated and M. bovis-infected cattle. BCG vaccine has been shown to reduce the spread of tuberculous lesions in a range of wildlife species and a prototype oral bait delivery system has been developed. Prospects for the development of improved vaccines against bovine tuberculosis are promising and vaccination approaches could become very valuable in the control and eradication of bovine tuberculosis.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, vaccines, vaccine development, wild animals, wildlife vaccination program, animal diseases, tuberculosis, vaccination, disease control, disease control programs, disease reservoirs, BCG vaccine, virulence, disease diagnosis, diagnostic techniques.
Buick, W. TB in domestic species other than cattle and badgers. GVJ Government Veterinary Journal. 2006; 16 (1): 87-91. ISSN: 0269-5545
URL: http://www.defra.gov.uk/animalh/gvj/default.htm
Descriptors: badgers (Meles meles), Camelidae, cats, cattle, dogs, ferrets, goats, sheep, horses, pigs, Mycobacterium bovis, clinical picture, susceptibility to pathogen.
Buncic, S. Zoonotic diseases in farm animals. Integrated Food Safety and Veterinary Public Health. 2006: 57-76. ISBN: 0851999085; 9780851999081. Note: Book chapter.
NAL Call Number: RA601.S28 2006
Descriptors: farm animals, livestock, animal and human diseases, disease transmission, epidemiology bovine spongiform encephalopathy, prion diseases, brucellosis, glanders, listeriosis, mycoses, parasitoses, protozoal infections; tuberculosis, viral diseases, zoonoses, avian influenza virus; Brucella abortus, Brucella suis, Burkholderia mallei, Erysipelothrix rhusiopathiae, Listeria, Mycobacterium bovis; Mycobacterium tuberculosis, Taenia saginata, Taenia solium, Trichinella pseudospiralis, West Nile virus, zoonoses.
Buxton, David. Wildlife and the risk to humans and domestic animals: A case for disease surveillance. Veterinary Journal. 2006; 171 (2): 204-205. ISSN: 1090-0233
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/623077/description#description
NAL Call Number: SF601.V484
Descriptors: wildlife as disease reservoirs, zoonotic diseases, humans, domestic animals, parasites, bison, wolf, red deer, reindeer, sika deer, elk, Mycobacterium bovis, nematodes, sarcosystis.
Cassidy, J.P. The pathogenesis and pathology of bovine tuberculosis with insights from studies of tuberculosis in humans and laboratory animal models. Veterinary Microbiology. 2006. 112 (2-4): 151-161. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: This paper reviews key insights the discipline of pathology has contributed to our understanding of bovine tuberculosis in the context of findings of studies of tuberculosis in humans and laboratory animal models. Analysis and extrapolation of data from other species have the potential to expand our understanding of the pathogenesis of the disease in cattle. The distribution of lesions in affected cattle, humans and laboratory animals illustrate the primacy of the respiratory tract as portal of infection and raise questions about the role of the upper respiratory tract surface, tonsil and dorsal lung regions in disease pathogenesis and transmission. The mechanisms behind significant pathological processes such as necrosis, apoptosis and liquefaction, occurring within lesions, are explored and their potential practical significance assessed in the context of herd disease dynamics and vaccine development. It is proposed that effective 'innate' host defenses result in many animals and humans remaining disease-free and tuberculin test negative following exposure to infection. Furthermore, the concepts of latency and disease reactivation, considered significant factors in perpetuating tuberculosis in human populations, are explored in the context of the bovine disease.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, animal disease models, pathogenesis, humans, tuberculosis, zoonoses, alternative hosts, respiratory system, disease course, infection, necrosis, apoptosis, resistance mechanisms, latent period, relapse, liquefaction.
Cataluna, R.L.N.; Gordoncillo, M.J.N. Cervical fold tuberculin testing in cattle (Bos indicus) and water buffaloes (Bubalus bubalis) in Los Banos, Laguna. Philippine Journal of Veterinary Medicine. 2006; 43 (2): 103-105. ISSN: 0031-7705
Descriptors: water buffalo, cattle, bovine tuberculosis, Mycobacterium bovis, disease surveillance, PPD tuberculin test, bacterial testing, zoonotic potential, Philippines.
Cockle, P.J.; Gordon, S.V.; Hewinson, R.G.; Vordermeier, H.M. Field evaluation of a novel differential diagnostic reagent for detection of Mycobacterium bovis in cattle. Clinical and Vaccine Immunology. 2006; 13 (10): 1119-1124. ISSN: 1556-6811
URL: http://cvi.asm.org/
Descriptors: cattle; Mycobacterium bovis; immunodominant peptides from Rv3873, Rv3879c, Rv0288, Rv3019c; lead diagnostic antigens ESAT-6 and CFP-10; peptide cocktail; better than M. bovis BCG vaccination; serological diagnosis.
Collins, J.D. The approach to eradication of tuberculosis in cattle: an Irish perspective. Cattle Practice. 2006; 14 (1): 1-6. ISSN: 0969-1251
NAL Call Number: SF961.C37
Abstract: With regards to tuberculosis in cattle, the challenge to Irish agriculture is to ensure that all the stakeholders realize that without their full participation, the persistence of this disease in the national herd will continue to be a drain on the national economy and will threaten Ireland's ability to trade internationally as a supplier of high quality beef and dairy products at some time in the future. Scientific evaluation of data from the past 30 years indicates that eradication is achievable on a regional and national basis. This is provided the status of clear herds is maintained through vigilance and active cooperation between herd owners and the regulatory authorities and that a holistic approach to eradication is supported by effective risk communication at local and national level, and that defined and agreed targets are adopted and achieved on schedule. The respective roles of members of the veterinary profession in government service and, in particular, of those engaged by the owners of herds that are clear of tuberculosis and by owners of infected herds, demand a professional performance of the highest standard and the exercise of due diligence at every level to ensure the prevention, control and eradication of this zoonotic disease.
Descriptors: beef cattle, dairy cattle, Mycobacterium bovis, impact of disease on trade, dairy and beef product quality, role of veterinarians, disease prevention and control programs, Irish Republic.
Collins, J.D. Tuberculosis in cattle: strategic planning for the future. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 369-381. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: In the later stages of eradication of tuberculosis in cattle there is a need to take account of the fact that Mycobacterium bovis infection in cattle presents, not as cases of clinical disease but most commonly as apparently healthy animals showing an immunological response to tuberculin. This is an entirely different scenario to that seen when national eradication programmes were first devised, at a time when the protection of public health rather than animal health was the prime motivation. In countries with active programmes to eradicate bovine tuberculosis, it is critical for the programme's success that account is taken of this redefinition of tuberculosis, side by side with changes in modern animal production systems and their impact on the transmission of M. bovis. This paper highlights factors critical to the success of a national eradication programme, including a clear identification of the goals, of the policies that guide actions, and of the sequences of actions that are required within the programme to accomplish these goals. Experience has illustrated the adverse effects of compromise on outcome when the application of fundamental principles of disease control such as sound animal management, removal of known sources of infection, early diagnosis, quarantine, movement control and environmental hygiene are less than enthusiastically promoted and applied. The reality is that where these principles are applied in a sustained manner, the outcome is more likely to be successful. Therein lies the challenge for the risk manager.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, program planning, disease control programs, decision making, latent period, animal husbandry, disease transmission, agricultural policy, control methods, risk management, health policy, pathogen eradication.
Corner, L.A.L. The role of wild animal populations in the epidemiology of tuberculosis in domestic animals: how to assess the risk. Veterinary Mcrobiology. 2006 Feb. 25; 112 (2-4): 303-312. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: Tuberculosis is present in wild animal populations in North America, Europe, Africa and New Zealand. Some wild animal populations are a source of infection for domestic livestock and humans. An understanding of the potential of each wild animal population as a reservoir of infection for domestic animals is reached by determining the nature of the disease in each wild animal species, the routes of infection for domestic species and the risk of domestic animals encountering an infectious dose. The mere presence of infection in a wild animal population does not of itself provide evidence of a significant wildlife reservoir. Although at times counterintuitive, wildlife populations with high disease prevalence may not necessarily have a role in the epidemiology of disease in domestic livestock. The key concepts used in deciding whether an infected wild animal population is involved in the epidemiology of tuberculosis in domestic livestock is illustrated by reference to six well-researched cases: the feral pig (Suis scrofa) and feral Asian water buffalo (Bubalus bubalis) in Australia, white tailed deer (Odocoileus virginianus) in Michigan, and the brushtail possum (Trichosurus vulpecula) and other species, such as the ferret (Mustela furo), in New Zealand. A detailed analysis of Mycobacterium bovis infection in the Eurasian badger (Meles meles) in Ireland and their role as a reservoir of infection for cattle is also presented.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, wild animals, wildlife, animal diseases, tuberculosis, alternative hosts, risk assessment, disease transmission, infection, disease prevalence, disease outbreaks, case studies, disease reservoirs.
Coryn, H.D. Badgers, TB and modern farming practice. Veterinary Record. 2006; 158 (17): 604. ISSN: 0042-4900. Note: Correspondence.
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: cattle, badgers (Meles meles), Mycobacterium bovis, relationship with modern farming practices, UK.
Cvetnic, Z.; Ocepek, M.; Lojkic, M.; Markus Cizelj, L.; Spicic, S.; Pate, M.; Krt, B. Usporedba tuberkulinskog i Mycobacterium bovis gama interferonskog ( gamma -IFN) testa u dijagnostici i tuberkuloze goveda. [Comparison of tuberculin skin test and Mycobacterium bovis gamma interferon ( gamma -IFN) test in diagnosis of bovine tuberculosis.] Praxis Veterinaria Zagreb. 2006; 54 (1/2): 41-49. ISSN: 0350-4441. Note: In Croatian with an English summary.
URL: http://www.veterina.hr/pdf/PV122006.pdf
Descriptors: cattle, tuberculin skin test and gamma interferon diagnostic tests, comparison study, Mycobacterium bovis.
Cvetnic, Z.; Spicic, S.; Katalinic-Jankovic, V.; Marjanovic, S.; Obrovac, M.; Benic, M.; Mitak, M.; Pavlik, I. Mycobacterium caprae infection in cattle and pigs in one family farm in Croatia: a case report. Veterinarni Medicina. 2006; 51 (11): 523-531. ISSN:
URL: http://vetmed.vri.cz
NAL Call Number: 41.9 C333
Descriptors: cattle, pigs, Mycobacterium caprae, family farm, tuberculin skin test, bovine PPD, postmortem exam, submandibular lymphnode lesions, isolates identified, classical and molecular methods, first case of Mycobacterium caprae in pigs, Croatia.
Daykin, J.; Pepper, B.; Green, R.; Howe, C.; Swarbrick, O. Badger culling consultation. Veterinary Record (London). 2006; 159 (7): 220. ISSN: 0042-4900
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: badgers, cattle, Mycobacterium bovis, bovine tuberculosis, rules, UK.
de la Rua Domenech, R.; Goodchild, A.T.; Vordermeier, H.M.; Hewinson, R.G.; Christiansen, K.H.; Clifton-Hadley, R.S. Ante mortem diagnosis of tuberculosis in cattle: A review of the tuberculin tests, (Sd(B-interferon assay and other ancillary diagnostic techniques. Research in Veterinary Science. 2006 Oct; 81 (2): 190-210. ISSN: 0034-5288
URL: http://dx.doi.org/10.1016/j.rvsc.2005.11.005
NAL Call Number: 41.8 R312
Abstract: The early, preclinical stages of bovine TB can be detected in live animals by the use of tests of cellular immunity (the skin, (Sd(B-interferon and lymphocyte transformation tests). Tests of humoral (antibody) immunity, Mycobacterium bovis PCR probes on early tissue cultures or live cattle specimens, and tests based on "electronic nose" technology have been developed more recently. The key measure of diagnostic test accuracy is the relationship between sensitivity and specificity, which determines the false-positive and false-negative proportions. None of the tests currently available for the diagnosis of bovine TB allow a perfectly accurate determination of the M. bovis infection status of cattle. Although various factors can reduce the sensitivity and specificity of the skin tests, these remain the primary ante mortem diagnostic tools for TB in cattle, providing a cost-effective and reliable means of screening entire cattle populations. Despite the inescapable limitations of existing diagnostic tests, bovine TB has been effectively eradicated from many developed countries and regions with the implementation of sound programmes of regular tuberculin skin testing and removal of reactors, coupled with slaughterhouse surveillance for undetected infections, repeat testing and culling of infected herds, cattle movement restrictions to prevent introduction of infected animals and occasional slaughter of entire herds with intractable breakdowns. This is likely to remain the mainstay of bovine TB control programmes for the foreseeable future. Additionally, newer ancillary in vitro diagnostic assays are now available to TB control programme managers to supplement the skin tests in defined circumstances according to the specific disease situation in each country or region. The strategic deployment of ancillary in vitro tests alongside the primary skin tests has enhanced the detection of M. bovis-infected cattle and reduced the number of animals slaughtered as false positives.
Descriptors: cattle, bovine tuberculosis; Mycobacterium bovis, disease diagnosis, tuberculin, interferons, diagnostic techniques, humoral immunity, PCR, polymerase chain reaction, literature reviews, skin tests, lymphocyte proliferation, electronic nose, accuracy, disease control programs, test specificity, test sensitivity,
Diguimbaye Djaibe, Colette; Hilty, Markus; Ngandolo, Richard; Mahamat, Hassane H.; Pfyffer, Gaby E.; Baggi, Franca; Hewinson, Glyn; Tanner, Marcel; Zinsstag, Jakob; Schelling, Esther. Mycobacterium bovis isolates from tuberculous lesions in Chadian zebu carcasses. Emerging Infectious Diseases. 2006; 12 (5): 769-771. ISSN: 1080-6040.
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?linkbar=plain&db=journals&term=1080-6040
NAL Call Number: RA648.5.E46
Descriptors: zebu cattle, Arabe breed, Mboboro breed, kouri breed, Mycobacterium bovis, Mycobacterium bovis, slaughterhouse study, breed differences, trans-border and ongoing transmission indicated, Chad, Cameroon, Nigeria.
Donnelly, C.A.; Woodroffe, R.; Cox, D.R.; Bourne, F.J.; Cheeseman, C.L.; Clifton-Hadley, R.S.; Wei, G.; Gettinby, G.; Gilks P.; Jenkins H. Positive and negative effects of widespread badger culling on tuberculosis in cattle \h [electronic resource]. Nature. 2006 Feb. 16; 439 (7078): 843-846. ISSN: 1476-9679
URL: http://dx.doi.org/10.1038/nature04454
NAL Call Number: 472 N21
Descriptors: cattle, bovine tuberculosis, Mycobacterium bovis, disease control, disease reservoirs, badgers, Meles meles, culling animals, disease prevalence, disease incidence, geographical distribution, United Kingdom.
Everett, R.E. Eradication of bovine TB: learning from other countries. Veterinary Record (London). 2006; 158 (18): 640. ISSN: 0042-4900
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: buffalo, cattle, bovine tuberculosis, Mycobacterium bovis, disease control and eradication, Australia, New South Wales, Northern Territory, Queensland, Western Australia.
Fischer, O.A.; Matlova, L.; Dvorska, L.; Svastova, P.; Bartos, M.; Weston, R.T.; Pavlik, I. Various stages in the life cycle of syrphid flies (Eristalis tenax; Diptera: Syrphidae) as potential mechanical vectors of pathogens causing mycobacterial infections in pig herds. Folia Microbiologica. 2006; 51 (2): 147-153
URL: http://www.biomed.cas.cz/mbu/folia/
Descriptors: pigs, syrphid flies, Eristalis tenax, insect vectors, disease carriers, survival and transmission, Mycobacterium chelonae, Mycobacterium avium ssp avium, Mycobacterium avium ssp hominissuis.
Foote, M.; Nonnecke, B.; Waters, W.; Beitz, D.; Fowler, M.; Johnson, T.; Miller, B. High growth rate fails to enhance adaptive immune responses of neonatal calves and is associated with decreased T cell viability. Journal of Animal Science. 2006; 84 (Suppl. 1): 163-164. ISSN: 0021-8812. Note: 2006 ADSA/ASAS Joint Annual Meeting, Minneapolis, MN, USA; July 09 -13, 2006
URL: http://www.asas.org
NAL Call Number: 49 J82
Descriptors: cattle, neonates, Mycobacterium bovis, growth rates, serum testing, adaptive immune response, decreased T cell viability, CD4 Positive T cells, CD8 positive T cells, mononuclear leukocytes.
Gagea, M.I.; Bateman, K.G.; Van Dreumel, T.; McEwen, B.J.; Carman, S.; Archambault, M.; Shanahan, R.A.; Caswell, J.L. Diseases and pathogens associated with mortality in Ontario beef feedlots. Journal of Veterinary Diagnostic Investigation. 2006 Jan; 18 (1) 18-28. ISSN: 1040-6387
URL: http://jvdi.org/
NAL Call Number: SF774.J68
Descriptors: calves, beef cattle, cattle diseases, animal pathogens, animal feeding operations, feedlots, disease incidence, disease prevalence, disease detection, bacterial infections, zoonotic viral diseases, Mycobacterium bovis, Mannheimia haemolytica, Haemophilus somnus, respiratory tract diseases, bacterial pneumonia, morbidity, mortality, bovine viral diarrhea virus, arthritis, pneumonic pasteurellosis, emerging diseases, Ontario
Gallagher, J.; Muirhead, R.H.; Turnbull, A.T.; Davies, J.I.; Ashton, W.L.G.; Smith, J.; Daykin, J.; McDiarmid, A. TB policy and the badger culling trials. Veterinary Record (London). 2006; 158 (9): 310-311. ISSN: 0042-4900
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: badgers, (Meles meles), cattle, Mycobacterium bovis, disease eradication and control, government policies, UK.
Gallagher, J.; Muirhead, R.H.; Turnbull, A.T.; Davies, J.I.; Ashton, W.L.G.; Smith, J.; Daykin, J.; McDiarmid, A. TB policy and the badger culling trials. Veterinary Record (London). 2006; 159 (7): 220. ISSN: 0042-4900
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: badgers, Mycobacterium bovis, bovine tuberculosis, policies, wildlife disease reservoirs, disease transmission, culling of badgers.
Gallagher, J.; Muirhead, R.H..; Turnbull, A.T.; Davies, J.I.; Ashton, W.L.G.; Smith, J.; Daykin, J.; McDiarmid, A. TB policy and the badger culling trials. Veterinary Record (London). 2006; 158 (15): 524. ISSN: 0042-4900
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: badgers (Meles meles), cattle, Mycobacterium tuberculosis.
Ganesan, P.I. Excretion of mycobacteria in cattle. Indian Veterinary Journal. 2006; 83 (10): 1112-1113. ISSN: 0019-6479
URL: www.indvetjournal.com
NAL Call Number: 41.8 IN2
Descriptors: cattle, identification of infected animals, respiratory excretion of Mycobacterium bovis, nasal swab smears, SID test, intradermal tuberculin, experimental infection.
Gobena Ameni; Abraham Aseffa; Engers, H.; Young, D.; Hewinson, G.; Vordermeier, M. Cattle husbandry in Ethiopia is a predominant factor affecting the pathology of bovine tuberculosis and gamma interferon responses to mycobacterial antigens. Clinical and Vaccine Immunology. 2006; 13 (9): 1030-1036. ISSN: 1556-6811
URL: http://cvi.asm.org/
Abstract: Bovine tuberculosis is a major economic problem and a potential public health risk. Improved diagnostics like the gamma interferon (IFN-gamma ) test with ESAT6 and/or CFP10 could contribute to the control program. We assessed IFN- gamma responses in zebu (Ethiopian Arsi breed) and Holstein cattle kept indoors or in a pasture to tuberculin purified protein derivative (PPD) and an ESAT6-CFP10 protein cocktail. Furthermore, the intensity and distribution of pathology of bovine tuberculosis were compared between the two breeds. Our data demonstrated significantly (all P<0.02) higher IFN- gamma responses to avian PPD, bovine PPD, and the ESAT6-CFP10 protein cocktail in Holstein than in zebu cattle, while lesion severities in infected animals and tuberculin skin test responses did not differ significantly (P>0.05) between the two breeds. Holstein cattle that were kept indoors produced significantly (all P<0.01) higher IFN- gamma levels in response to avian PPD, bovine PPD, and the ESAT6-CFP10 protein cocktail than did Holstein cattle kept in a pasture. Moreover, lesion severity was significantly higher in Holstein cattle kept indoors (P=0.001) than in those kept in the pasture. Lesions were localized predominantly in the digestive tract in cattle kept in a pasture, while they were localized in the respiratory tract in cattle kept indoors. In conclusion, in Holstein cattle, husbandry was a dominant factor influencing the severity of tuberculosis lesions and IFN-gamma responses to mycobacterial antigens compared to breed. A difference in the cellular immune response between zebu and Holstein cattle was observed, while tuberculosis lesion severities were identical in the two breeds, when both were kept in a pasture..
Descriptors: zebu cattle, Holstein cattle, Mycobacterium bovis, zebu, indoor housing, pastured animals, improved diagnostics, gamma interferon (IFN-gamma ) test with ESAT6 and/or CFP10, Ethiopia, Abyssinia.
Godden, S.; McMartin, S.; Feirtag, J.; Stabel, J.; Bey, R.; Goyal, S.; Metzger, L.; Fetrow, J.; Wells, S.; Chester-Jones, H. Heat-treatment of bovine colostrum. II: Effects of heating duration on pathogen viability and immunoglobulin G. Journal of Dairy Science. 2006 Sept; 89 (9): 3476-3483. ISSN: 0022-0302
NAL Call Number: 44.8 J822
Abstract: Batches (30-L) of first-milking bovine colostrum, inoculated with Mycoplasma bovis (10 superscript 8(B cfu/mL), Listeria monocytogenes (10 superscript 6(B cfu/mL), Escherichia coli O157:H7 (10 superscript 6(B cfu/mL), Salmonella enteritidis (10 superscript 6(B cfu/mL), and Mycobacterium avium subsp. paratuberculosis (Map; 10 superscript 3(B cfu/mL), were heat-treated at 60AC for 120 min in a commercial on-farm batch pasteurizer system. Duplicate 50-mL subsamples of colostrum were collected at 15-min intervals throughout the heat-treatment process for the purpose of bacterial culture and for measurement of IgG concentration (mg/mL) and antibody activity [log subscript 2(B(bovine viral diarrhea virus type 1 serum neutralization titer)]. Four replicate batches of colostrum were run for each of the 5 pathogens studied. There was no effect of heating moderate- to high-quality colostrum at 60AC for at least 120 min on mean IgG concentration (pre = 60.5 mg/mL; post = 59.1 mg/mL). Similarly, there was no effect of heat-treatment on the mean log subscript 2(B bovine viral diarrhea virus type 1 serum neutralization titer (pre = 12.3; post = 12.0). Viable M. bovis, L. monocytogenes, E. coli O157:H7, and S. enteritidis added to colostrum could not be detected after the colostrum was heat-treated at 60AC for 30 min. Average bacteria counts showed that Map was not detected when batches were heated at 60AC for 60 min. Although the authors believe that heat-treating colostrum at 60AC for 60 min should be sufficient to eliminate Map from colostrum in most situations, further research is needed to determine whether these findings may be replicated, given that variability was observed in Map culture results.
Descriptors: first milking colostrum, inoculation with Mycoplasma bovis, Mycobacterium avium paratuberculosis, Salmonells enteritidis, Listeria monocytogenes, Escherichia coli, heat treatment process to inactivate the pathogens.
Godden, S.; McMartin, S.; Feirtag, J.; Stabel, J.; Bey, R.; Goyal, S.; Metzger, L.; Fetrow, J.; Wells, S.; Chester-Jones, H. Heat-treatment of bovine colostrum. II: Effects of heating duration on pathogen viability and immunoglobulin G. Journal of Dairy Science. 2006 Sept; 89 (9): 3476-3483. ISSN: 0022-0302
URL: http://jds.fass.org/cgi/content/full/89/9/3476
NAL Call Number: 44.8 J822
Abstract: Batches (30-L) of first-milking bovine colostrum, inoculated with Mycoplasma bovis (10 superscript 8(B cfu/mL), Listeria monocytogenes (10 superscript 6(B cfu/mL), Escherichia coli O157:H7 (10 superscript 6(B cfu/mL), Salmonella enteritidis (10 superscript 6(B cfu/mL), and Mycobacterium avium subsp. paratuberculosis (Map; 10 superscript 3(B cfu/mL), were heat-treated at 60AC for 120 min in a commercial on-farm batch pasteurizer system. Duplicate 50-mL subsamples of colostrum were collected at 15-min intervals throughout the heat-treatment process for the purpose of bacterial culture and for measurement of IgG concentration (mg/mL) and antibody activity [log subscript 2(B(bovine viral diarrhea virus type 1 serum neutralization titer)]. Four replicate batches of colostrum were run for each of the 5 pathogens studied. There was no effect of heating moderate- to high-quality colostrum at 60AC for at least 120 min on mean IgG concentration (pre = 60.5 mg/mL; post = 59.1 mg/mL). Similarly, there was no effect of heat-treatment on the mean log subscript 2(B bovine viral diarrhea virus type 1 serum neutralization titer (pre = 12.3; post = 12.0). Viable M. bovis, L. monocytogenes, E. coli O157:H7, and S. enteritidis added to colostrum could not be detected after the colostrum was heat-treated at 60AC for 30 min. Average bacteria counts showed that Map was not detected when batches were heated at 60AC for 60 min. Although the authors believe that heat-treating colostrum at 60AC for 60 min should be sufficient to eliminate Map from colostrum in most situations, further research is needed to determine whether these findings may be replicated, given that variability was observed in Map culture results.
Descriptors: first milking colostrum, inoculation with Mycoplasma bovis, Mycobacterium avium paratuberculosis, Salmonells enteritidis, Listeria monocytogenes, Escherichia coli, heat treatment process to inactivate the pathogens.
Gomes da Silva, Paulo Eduardo; Pinheiro, Sonia Regina; Lizandra do Rego Leal, Marta; Bertagnon, Heloisa Godoi; Pinto-Coelho-Motta, Pedro Moacyr; Sinhorini, Idercio Luiz; Vasconcellos, Silvio-Arruda; Benesi, Fernando Jose. Teste de tuberculinizacao em caprinos (Capra hircus) experimentalmente sensibilizados. [Tuberculin test in experimentally sensitized goats (Capra hircus)] Ciencia Rural. 2006; 36 (3): 880-886. ISSN: 0103-8478. Note: In Portuguese.
URL: http://www.scielo.br/scielo.php/script_sci_serial/pid_0103-8478/lng_en/nrm_iso
NAL Call Number: S192.R4
Descriptors: goats, 3 groups, Myobacterium avium D4, Mycobacterium bovis AN5, control with saline, tuberculin testing, skin sampling, mononuclear inflammatory infiltrate of 96h after tuberculin inoculation.
Gopal, R.; Goodchild, A.; Hewinson, G.; Domenech, R. de la R.; Clifton-Hadley, R. Introduction of bovine tuberculosis to north-east England by bought-in cattle. Veterinary Record (London). 2006; 159 ( 9): 265-271. ISSN: 0042-4900
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: cattle herds, bovine tuberculosis, Mycobacterium bovis, restocking after FMD in 2001, infected purchased animals, spoligotype and variable numbe tandem repeats indicated souce was Wales, Cheshire herds, Irish imports, Britain, England.
Good, M. Bovine tuberculosis eradication in Ireland. Irish Veterinary Journal. 2006; 59 (3): 154-162. ISSN: 0368-0762
URL: www.veterinary-ireland.org
NAL Call Number: 41.8 IR4
Descriptors: cattle, bovine tuberculosis, eradication program started in 1950, European trading condition for live animals, reduction in disease levels, Mycobacterium bovis levels, wild badgers (Meles meles), disease reservoirs, disease transmission, disease prevention and control in wild animals, Ireland.
Gormley, E.; Doyle, M.B.; Fitzsimons, T.; McGill, K.; Collins, J.D. Diagnosis of Mycobacterium bovis infection in cattle by use of the gamma-interferon (Bovigam) assay. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4) 171-179. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: The strategic use of the gamma-interferon (IFN-gamma) assay (Bovigam) can provide a means for the early identification of Mycobacterium bovis infected cattle, thus ensuring their removal from an infected herd. When used in parallel with the tuberculin test, it is capable of identifying infected cattle, which might otherwise not be detected until later, if at all. The early detection and removal of these animals reduces the risk that they will become a source of infection for other cattle. When targeted in herds of high prevalence the benefits to the herd owner directly concerned can be considerable as the assay provides a means of shortening the period of restriction for such herds. This serves to generate confidence among herd owners and other stakeholders that effective schemes, based on sound scientific principles, can be developed to eradicate tuberculosis from infected cattle populations.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease diagnosis, interferons, diagnostic techniques, tuberculin, culling animals, early diagnosis, disease transmission, disease prevalence, disease control, disease control programs.
Gordejo, F.J. Reviriego.; Vermeersch, J.P. Towards eradication of bovine tuberculosis in the European Union. Veterinary Microbiology. 2006; 112 (2-4, Sp. Iss. SI): 101-109. ISSN: 0378-1135
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Descriptors: eradication of bovine tuberculosis, historical review, legislation, cattle trade, cattle breeding systems, environmental condition, epidemiology, Mycobacterium bovis, summary of the current statue of the disease, EU policies.
Griffin, J.F.T.; Rodgers, C.R.; Liggett, S.; Mackintosh, C.G. Tuberculosis in ruminants: characteristics of intra-tonsilar Mycobacterium bovis infection models in cattle and deer. Tuberculosis. 2006; 86 (6): 404-418. ISSN: 1472-9792
URL: http://www.sciencedirect.com/science/journal/14729792
Descriptors: cattle, red deer (Cervus elaphus), Mycobacterium bovis, intra-tonsilar, immunity reactions, immunological reactions, resistance to disease, susceptibility to disease, species comparison.
Hancox, M. Confusion over cattle tuberculosis. Letters in Applied Microbiology. 2006; 43 (2): 236. ISSN: 0266-8254
URL: http://www3.interscience.wiley.com/journal/118581679/abstract
Descriptors: badgers (Meles meles), cattle, Mycobacterium tuberculosis, species differences in lung lesions, transmission between cattle and badgers, routes of infection.
Hermoso de Mendoza, J.; Parra, A.; Tato, A.; Alonso, J.M.; Rey, J.M.; Pena, J.; Garcia-Sanchez, A.; Larrasa, J.; Teixido, J.; Manzano, G. Bovine tuberculosis in wild boar (Sus scrofa), red deer (Cervus elaphus) and cattle (Bos taurus) in a Mediterranean ecosystem (1992-2004). Preventive Veterinary Medicine. 2006 May 17; 74 (2-3): 239-247. ISSN: 0167-5877
URL: http://dx.doi.org/10.1016/j.prevetmed.2005.10.005
NAL Call Number: SF601.P7
Descriptors: cattle, cattle diseases, wild boars, Sus scrofa, red deer, Cervus elaphus, paratuberculosis, Mycobacterium bovis; epidemiological studies, disease transmission, wildlife livestock relations, game animals, risk assessment, ecosystems, disease surveillance, disease prevalence, disease detection, wildlife management, Spain.
Hewinson, R.G.; Vordermeier, H.M.; Smith, N.H.; Gordon, S.V. Recent advances in our knowledge of Mycobacterium bovis: a feeling for the organism. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 127-139. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: Significant and rapid progress has been made in our knowledge and understanding of Mycobacterium bovis since the last international M. bovis conference 5 years ago. Much of this progress has been underpinned by the completion of the genome sequence. This important milestone has catalysed research into the development of a number of improved tools with which to combat bovine tuberculosis. In this article we will review recent progress made in the development of these tools and in our understanding of the organism, its evolution and spread. Comparison of the genome sequence with those of other members of the Mycobacterium tuberculosis complex has enabled insights into the evolution of M. bovis. This analysis also indicates that the M. tuberculosis complex have the propensity to adapt to new host species. The use of high throughput molecular typing methods has revealed that the recent bovine tuberculosis epidemic in Great Britain is being driven by a number of clonal expansions, which cannot be explained by random mutation and drift alone. Completion of a number of mycobacterial genome sequences has allowed the development of antigen mining techniques that rapidly identify M. bovis-specific genes. These can then be used as reagents in the gamma interferon assay to increase the specificity of the assay and also to discriminate between Bacillus of Calmette and Guerin (BCG) vaccinated animals and those infected with M. bovis. In the longer term, comparisons between the genomes of M. bovis and BCG will allow insight into how BCG became attenuated following serial passage on artificial growth media and reveal clues into how to improve the vaccine efficacy of BCG.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, genomics, nucleotide sequences, microbial genetics, genome, evolution, host range, adaptation, disease outbreaks, genetic drift, bacterial antigens, BCG vaccine, vaccination, molecular sequence data.
Hines, N.; Payeur, J.B.; Hoffman, L.J. Comparison of the recovery of Mycobacterium bovis isolates using the BACTEC MGIT 960 system, BACTEC 460 system, and Middlebrook 7H10 and 7H11 solid media. Journal of Veterinary Diagnostic Investigation. 2006 May; 18 (3): 243-250. ISSN: 1040-6387
URL: http://jvdi.org/
NAL Call Number: SF774.J68
Descriptors: cattle, lymph nodes, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, strains, pathogen identification, diagnosis, culture media, tissue analysis, niacin, nitrates, microbial contamination, disease detection, new methods.
Horwitz, Marcus A.; Harth, Guenter; Dillon, Barbara Jane; Maslesa-Galic, Sasa. A novel live recombinant mycobacterial vaccine against bovine tuberculosis more potent than BCG. Vaccine. 2006; 24 (10): 1593-1600. ISSN: 0264-410X URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/30521/description#description
Descriptors: vaccination, cattle, other domesticated animal diseases, wild animal as disease reservoirs, Mycobacterium bovis, live recombinant vaccine, rBCG30 expresses large amounts of the Mycobacterium tuberculosis, 30kDa major secretory protein, more efficacious against bovine tuberculosis than BCG, aerosol challenge.
Jahans, K.; Worth, D. The laboratory diagnosis of bovine tuberculosis. GVJ-Government Veterinary Journal. 2006; 16 (1): 53-57. ISSN: 0269-5545
URL: http://www.defra.gov.uk/animalh/gvj/default.htm
Descriptors: cattle, Mycobacterium bovis, diagnosis, intradermal tests, PCR, zoonotic infections.
Johnson, Linda; Gough, Julie; Spencer, Yvonne; Hewinson, Glyn; Vordermeier, Martin; Wangoo, Arun. Immunohistochemical markers augment evaluation of vaccine efficacy and disease severity in bacillus Calmette-Guerin (BCG) vaccinated cattle challenged with Mycobacterium bovis. Veterinary Immunology and Immunopathology. 2006; 111(3-4): 219-229. ISSN: 0165-2427.
URL: http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number: SF757.2.V38
Abstract: Development of necrotic granulomas in response to Mycobacterium bovis infection in cattle is pathognomonic for bovine tuberculosis. Previously our laboratory reported on M. bovis granuloma classification by stage of lesion advancement within bovine lymph nodes and developed immunohistochemical markers to further characterize these granulomas. In this study of bovine lymph node granulomas we applied this classification system to assess the dynamics of vaccination challenge. Lymph nodes collected from cattle vaccinated with M. bovis bacillus Calmette-Guerin (BCG) and subsequently challenged with virulent M. bovis were compared to lymph nodes from unvaccinated, challenged cattle. Expression of interferon-(Sd(B (IFN-(Sd(B), transforming growth factor-(Sb(B (TGF-(Sb(B), type I procollagen and cell marker identification of T cells, B cells, macrophages and WC1+(Sd(Bdelta TCR+ cells were assessed. Granulomas formed in vaccinated cattle were greatly reduced in number, area, degree of necrosis and peripheral fibrosis and contained fewer Langhans' giant cells, acid fast bacilli, WC1+(Sd(Bdelta TCR+ cells and less TGF-(Sb(B expression in comparison to controls. B cells clustered intensely along the outer granuloma margins within vaccinated calves, with significantly more IFN-(Sd(B producing cells identified in the medullary regions of lymph nodes from BCG-vaccinated animals compared to unvaccinated controls. This may be indicative of immune activation and surveillance in regions not directly associated with ongoing disease. Lymph node evaluation using light microscopy and immunohistochemical markers is useful to assess the immune response and discriminate granulomas to determine vaccine efficacy and disease severity.
Descriptors: cattle, infected with Mycobacterium bovis BCG, virulent Mycobacterium bovis, necrotic granulomas, lesion classification, histochemical markers, lymph note granulomas, dynamics of vaccine challenge, IFN-gamma, TGF-beta, type I procollagen, cell marker identification of T cells, B cells, macrophages and WCl+gamma delta TCR+ cells.
Johnston, A.M. The 1901 Congress on Tuberculosis: John McFadyean and beyond. Veterinary Microbiology. 2006; 112 (2/4): 347-368. ISSN: 0378-1135. Note: Special issue: S.J.More, More; J.D. Collins; E. Gormley; M. Good; R.A. Skuce; J.M. Pollock (editors). Proceedings of the 4th International Conference on Mycobacterium bovis, Dublin, Ireland, 22-26 August 2005.
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Descriptors: Mycobacterium bovis, cattle, humans, historical congress discussed, disease transmission, epidemiology, tuberculin testing.
Kaneene, J.B.; Miller, R.; Meyer, R.M. Abattoir surveillance: the U.S. experience. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 273-282. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: Abattoir, or slaughter, surveillance has been an important component of bovine tuberculosis control and eradication programs in the U.S., and has adapted to changes in the livestock market from farm to table, and the threat of bovine tuberculosis from a wildlife reservoir. The purpose of this overview was to describe the current goals of U.S. bovine tuberculosis slaughter surveillance, describe the elements of slaughter surveillance in the U.S., describe enhancements to the slaughter surveillance system, and discuss future challenges for the U.S. bovine tuberculosis surveillance program. Government regulations and the scientific literature were examined to provide information for this paper. The control and eradication of bovine tuberculosis in livestock falls to the United States Department of Agriculture and two agencies within the Department: the Food Safety and Inspection Service (FSIS) and the Animal and Plant Health Inspection Service (APHIS). FSIS conducts routine slaughter surveillance for disease or conditions that render carcasses unsuitable for human consumption, while APHIS is involved in antemortem bovine tuberculosis testing, and necropsy and investigation of bovine tuberculosis cases identified through slaughter surveillance or antemortem testing. Results from the previous 5 years of surveillance are presented. Enhancements have been added to the current surveillance system to improve its performance. An incentive program has been used to increase the numbers of tissues submitted for laboratory examination, the state of Michigan is implementing electronic animal identification under a pilot program, and expansions to the current system are being developed to accommodate new livestock industries. The success of these programs and challenges for the future are discussed.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control, disease control programs, disease outbreaks, disease transmission, meat inspection, disease surveillance, slaughter, slaughterhouses, zoonoses, humans, tuberculosis, health policy, agricultural policy, pathogen eradication, United States.
Kantor, I.N. de; Ritacco, V. An update on bovine tuberculosis programmes in Latin American and Caribbean countries. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 110-119. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: Of the approximately 374 million cattle in Latin America and the Caribbean, 70% are held in areas where rates of Mycobacterium bovis infection in cattle are higher than 1%. The remaining 30% are in countries where infection affects less than 1% of cattle, including 62 million in countries where bovine tuberculosis infection is virtually nil. Measures for controlling bovine tuberculosis are partially or extensively applied in most of the countries in the Region. These measures are based on test and slaughter, notification, post-mortem inspection and surveillance in slaughterhouses. A coordinated production, standardization and quality control of purified protein derivatives is urgently required for use in control and eradication campaigns in order to assure reliability of reagents and comparability of data on tuberculin testing within the Region. On the basis of information from Argentina, M. bovis is estimated to cause 2% of all human cases of tuberculosis in the Region. Slaughterhouse and dairy farms workers are most-frequently infected, with infection occurring via the respiratory tract. Various in vitro assays for the diagnosis of bovine tuberculosis have been developed and/or assessed in the Region, and DNA fingerprinting has been applied for a comprehensive understanding of the epidemiology of bovine tuberculosis at the local and regional level.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, disease control, disease control programs, quarantine, literature reviews, disease incidence, epidemiology, agricultural policy, culling animals, disease surveillance, disease diagnosis, analytical kits, DNA profiling, zoonoses, public health, tuberculosis, humans, pathogen eradication, Latin America, Caribbean.
Karls, R. Tuberculosis in cattle: how to get the upper hand. Veterinary Journal. 2006; 171 (2): 193-194. ISSN: 1090-0233. Note: An editorial.
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/623077/description#description
NAL Call Number: SF601.V484
Descriptors: cattle, humans, Mycobacterium bovis, Mycobacterium tuberculosis, zoonotic disease, disease control, vaccine development, tuberculosis, vaccination.
Katoch, R.C.; Mandeep Sharma; Kisthwaria, R.S.; Subhash Verma; Rajinder Kumar. Confirmation of pulmonary tuberculosis by isolation and by PCR-RFLP in a crossbred cow. Indian Veterinary Journal. 2006; 83 (3): 338-339. ISSN: 0019-6479
URL: http://www.indvetjournal.com
NAL Call Number: 41.8 IN2
Descriptors: crossbred cow, Mycobacterium tuberculosis, bovine tuberculosis, pulmonary disease, case study, Himachal Pradesh, India.
Kazwala, R.R.; Kusiluka, L.J.M.; Sinclair, K.; Sharp, J.M.; DAbstractorn, C.J. The molecular epidemiology of Mycobacterium bovis infections in Tanzania. Veterinary microbiology. 2006 Feb. 25; 112 (2-4): 201-210. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: A molecular epidemiological study to determine the zoonotic importance of bovine tuberculosis was carried out in Tanzania. Specimens from human cases of tuberculosis as well as from slaughtered cattle were collected from regions with a high proportion of extrapulmonary tuberculosis. In order to determine the similarity of strains from the two sources, molecular typing techniques, namely RFLP and spoligotyping, were used to determine the genetic profile of the strains involved. The results of pTBN12 typing of M. bovis from cattle and man have shown a rather heterogeneous population of this species spread all over Tanzania, assuming that the present sample is representative. There were 13 different pTBN12 RFLP types encountered. The genetic relatedness between the pTBN12 RFLP patterns indicated a high degree of relatedness (86%) between the dominant pTBN12 genotypes existing in Tanzania. There were 13 different spoligotypes found in this study, whose genetic relatedness was also high (79%). DNA profiles were also confirmed by IS986 RFLP, which revealed that strains have 1-13 copies of IS986. Geographically, there was overlap between pTBN12 RFLP and spoligotypes amongst strains isolated from various parts of Tanzania. The diversity of the RFLP and spoligotype patterns observed in Tanzania probably reflects the extensive internal movements of cattle belonging to pastoralists. The evidence of overlap between DNA fingerprints of M. bovis from cattle and man has once more highlighted a need for synergy of veterinary and medical policies in the control of tuberculosis in Tanzania and probably in other developing countries.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, microbial genetics, disease incidence, strains, zoonoses, humans, tuberculosis, strain differences, pathogen identification, genotype, restriction fragment length polymorphism, genetic markers, geographical distribution, wildlife vaccination programs, Tanzania.
Khan, M.Z.; Khan, A. Basic facts of mastitis in dairy animals: a review. Pakistan Veterinary Journal. 2006; 26 (4): 204-208. ISSN: 0253-8318
Descriptors: buffalo, cattle, Corynebacterium, Escherichia coli, Mycobacterium, Mycobacterium tuberculosis, Mycoplasma, Pseudomonas, Staphylococcus, Staphylococcus aureus, Streptococcus, Streptococcus agalactiae, Streptococcus dysgalactiae, chemotherapy, milk constituents, milk contamination, Pakistan.
Kinne, J.; Johnson, B.; Jahans,K.L.; Smith, N.H.; Ul Haq, A.; Wernery, U. Camel tuberculosis-a case report. Tropical Animal Health and Production. 2006 Apr; 38 (3): 207-213. ISSN: 0049-4747
URL: http://dx.doi.org/10.1007/s11250-006-4366-8
NAL Call Number: SF601 .T7
Descriptors: dromedary camel, case report, Mycobacterium tuberculosis complex, tuberculosis, lungs, disease diagnosis, United Arab Emirates
Klerk, L. de; Michel, A.L.; Grobler, D.G.; Bengis, R.G.; Bush, M.; Kriek, N.P.J.; Hofmeyr, M.S.; Griffin, J.F.T.; MacKintosh, C.G. An experimental intratonsilar infection model for bovine tuberculosis in African buffaloes, Syncerus caffer. Onderstepoort Journal of Veterinary Research. 2006; 73 (4): 293-303. ISSN: 0030-2465
Descriptors: buffalo (Syncerus-caffer) cattle, high and low dose levels of Mycobacterium bovis, experimental infection, intratonsilar inoculation, vaccine evaluation, intradermal truberculin test, invitro modified interferon gamma assay, postmortem exam, lesion development assessed.
Kruuk, H. Control of badgers and bovine TB. Veterinary Record (London). 2006; 158 (13): 455. ISSN: 0042-4900. Note: Correspondence.
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: badgers (Meles meles), cattle, Mycobacterium bovis, disease, control, wildlife as a disease reservoir, UK.
Lambert, W.; Gobena-Ameni; Manaye, K.; Yalemtsehay, Mekonnen. Study on bovine tuberculosis in the Holeta dairy farm, Central Ethiopia. Journal of Animal and Veterinary Advances. 2006; 5 (12): 1150-1154. ISSN: 1680-5593
Descriptors: dairy cattle, farm study, Mycobacterium bovis, bovine tuberculosis, zoonotic disease, control measures, retesting a herd after 2 years, recommend regular testing and removal of TB positive animals, Ethiopia.
Leslie, N.W. Spread of bovine TB as a result of restocking. Veterinary Record (London). 2006; 159 (12): 396. ISSN: 0042-4900
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: cattle, disease transmission, movement of cattle to restock farms, Mycobacterium bovis, spread of disease.
Li, Jing Jing; Zhao, De Ming; Xu, Guang Xian; Zhou, Xiang Mei; Yin, Xiao Min. Cloning and expression of Mycobacterium bovis secreted protein MPB83 in Escherichia coli. Journal of China Agricultural University. 2006; 11 (6): 19-22. ISSN: 1007-4333. Note: In Chinese with an English summary.
NAL Call Number: S19.C58
Descriptors: Mycobacterium bovis, cloning of the MPB83 gene, analysis of its expression, SDS-PAGE and western blotting technique, possible diagnostic tool.
Li, Rui Fang; Qin, Ai Jian; Xu, Jin Jun. Preparation of the specific monoclonal antibody against bovine gamma -interferon and its properties. Chinese Journal of Zoonoses. 2006; 22 (8): 755-758. ISSN: 1002-2694. Note: In Chinese with an English summary.
Descriptors: cattle, Mycobacterium bovis, monoclonial, antibody, fusion SP2/0cells and immunized mice spleen cells, immunogen on BALB/cmice, BovIFN-gamma 4A3 BovIFN-gamma4G5, use for surveillance and control of TB in milk cows.
Lilenbaum, W.; Fonseca, L. de S. The use of ELISA as a complementary tool for bovine tuberculosis control in Brazil. Brazilian Journal of Veterinary Research and Animal Science. 2006; 43 (2): 256-261. ISSN: 1413-9596. Note: English with a Portuguese summary.
URL: http://www.scielo.br/scielo.php?script=sci_issues&pid=1413-9596&lng=en&nrm=iso
Descriptors: cattle, Mycobacterium bovis, control program, infected herds, lung lesions, culling animals, ELISA, serological testing, diagnostic tests, Rio de Janeiro, Brazil.
Livingstone, P.G.; Ryan, T.J.; Hancox, N.G.; Crews, K.B.; Bosson, M.A.J.; Knowles, G.J.E.; McCook, W. Regionalisation: a strategy that will assist with bovine tuberculosis control and facilitate trade. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 291-301. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: It is expected that the revised chapter on bovine tuberculosis in the Terrestrial Animal Health Code of the Office Internationale des Epizooties (OIE) will embrace regionalisation as a functional means of assisting countries, states or regions to meet the requirements for freedom from tuberculosis and to facilitate trade. The benefits and applications of regionalisation, which comprises zoning and compartmentalisation, are discussed. Regionalisation requires that a country's veterinary administration is able to implement transparent and auditable biosecurity measures that will ensure that the tuberculosis-free status of a subpopulation of cattle is maintained despite the presence of infection in another cattle subpopulation, or in other domestic or wild animal species. Zoning, which requires cattle subpopulations to be separated by geographic boundaries, provides a practical basis whereby countries, states or regions, can progress towards freedom from tuberculosis, regardless of the source of infection for defined cattle subpopulations. Compartmentalisation however, requires that husbandry or management practices will be used to prevent a tuberculosis-free cattle subpopulation from contacting inter-specific and intra-specific sources of infection. This will be difficult to achieve except for specialised cases such as artificial breeding centers.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control, disease control programs, international trade, disease transmission, biosecurity, disease prevention, wild animals, animal diseases, tuberculosis, geographical distribution, animal husbandry, disease surveillance, wildlife, case studies, disease reservoirs, pathogen eradication, regionalization, New Zealand.
Lopes, L.B.; Cunha, A.P. da; Mota, R.A.; Leite, R.C. Comparacao de duas tecnicas de tuberculinizacao em bufalos. [Comparison of two tuberculin tests in buffaloes.] Ciencia Animal Brasileira. 2006; 7 (2): 187-191. ISSN: 1518-2797
Descriptors: buffalo, 11 different herds, Mycobacterium bovis, diagnostic test, comparison study, single tuberculin test, comparative tuberculin test, mammalian antigen, combined mammalian and avian antigens, Brazil.
Macdonald, D.W.; Riordan, P.; Mathews, F. Biological hurdles to the control of TB in cattle: a test of two hypotheses concerning wildlife to explain the failure of control. Biological Conservation. 2006; 131 (2): 268-286. ISSN: 0006-3207
URL: http://www.sciencedirect.com/science/journal/00063207
NAL Call Number: S900.B5
Descriptors: badgers (Meles meles), wildlife as disease reservoirs, culling badgers, disease transmission, Mycobacterium bovis, bovine tuberculosis, control programs, disease surveillance, Britain, United Kingdom.
Mathews, Fiona; Macdonald, David W.; Taylor, G Michael; Gelling, Merryl; Norman, Rachel A.; Honess, Paul E.; Foster, Rebecca; Gower, Charlotte M.; Varley, Susan; Harris, Audrey; Palmer, Simonette; Hewinson, Glyn; Webster, Joanne P.
Bovine tuberculosis (Mycobacterium bovis) in British farmland wildlife: the importance to agriculture.
Proceedings of the Royal Society Biological Sciences Series B. 2006; 273 (1584): 357-365.
ISSN: 0962-8452
URL:
http://journals.royalsociety.org/home/main.mpx
NAL Call Number: 501 L848
Descriptors: British cattle herd, cattle diseases, Mycobacterium bovis, wildlife disease reservoirs, bank voles, badgers, pathogen levels, probably not the most important source of disease, economic costs.
Meade, K.G.; Gormley, E.; Park, S.D.E.; Fitzsimons, T.; Rosa, G.J.M.; Costello, E.; Keane, J.; Coussens, P.M.; MacHugh, D.E. Gene expression profiling of peripheral blood mononuclear cells (PBMC) from Mycobacterium bovis infected cattle after in vitro antigenic stimulation with purified protein derivative of tuberculin (PPD). Veterinary Immunology and Immunopathology. 2006; 113 (1/2): 73-89. ISSN: 0165-2427
URL: http://www.sciencedirect.com/science/journal/01652427
NAL Call Number: SF757.2.V38
Descriptors: cattle, Mycobacterium bovis, bovine tuberculosis, immunity reactions, immunological reactions, mRNA, peripheral blood mononuclear cells, purified protein derivative, PPD.
Michel, A.L.; Bengis, R.G.; Keet, D.F.; Hofmeyr, M.; de Klerk, L.M.; Cross, P.C.; Jolles, A.E.; Cooper, D.; Whyte, I.J.; Buss, P. Wildlife tuberculosis in South African conservation areas: implications and challenges. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 91-100. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: Tuberculosis, caused by Mycobacterium bovis, was first diagnosed in African buffalo in South Africa's Kruger National Park in 1990. Over the past 15 years the disease has spread northwards leaving only the most northern buffalo herds unaffected. Evidence suggests that 10 other small and large mammalian species, including large predators, are spillover hosts. Wildlife tuberculosis has also been diagnosed in several adjacent private game reserves and in the Hluhluwe-iMfolozi Park, the third largest game reserve in South Africa. The tuberculosis epidemic has a number of implications, for which the full effect of some might only be seen in the long-term. Potential negative long-term effects on the population dynamics of certain social animal species and the direct threat for the survival of endangered species pose particular problems for wildlife conservationists. On the other hand, the risk of spillover infection to neighboring communal cattle raises concerns about human health at the wildlife-livestock-human interface, not only along the western boundary of Kruger National Park, but also with regards to the joint development of the Greater Limpopo Trans-frontier Conservation Area with Zimbabwe and Mozambique. From an economic point of view, wildlife tuberculosis has resulted in national and international trade restrictions for affected species. The lack of diagnostic tools for most species and the absence of an effective vaccine make it currently impossible to contain and control this disease within an infected free-ranging ecosystem. Veterinary researchers and policy-makers have recognized the need to intensify research on this disease and the need to develop tools for control, initially targeting buffalo and lion.
Descriptors: African buffalo, (Syncerus caffer), wild animals, Mycobacterium bovis, animal pathogenic bacteria, tuberculosis, wildlife, animal diseases, conservation areas, disease outbreaks, alternative hosts, disease transmission, endangered species, literature reviews, lions (Panthera leo), disease control, disease reservoirs, South Africa, Zimbabwe, Mozambique.
Miller, R.A.; Kaneene, J.B. Evaluation of historical factors influencing the occurrence and distribution of Mycobacterium bovis infection among wildlife in Michigan. American Journal of Veterinary Research. 2006 Apr; 67 (4): 604-615. ISSN: 0002-9645.
NAL Call Number: 41.8 Am3A
Descriptors: cattle, white tailed deer, Mycobacterium bovis, bovine tuberculosis, disease reservoirs, spatial distribution, disease outbreaks, Odocoileus virginianus, temporal variation, risk factors, disease prevalence, wildlife livestock relations, population density, population size, environmental factors, animal husbandry, wildlife management, ribotypes, zoonoses, Michigan.
Mitchell, A. Bovine TB: modelling and predicting its distribution in GB using CTS data. GVJ-Government Veterinary Journal. 2006; 16 (1): 46-52. ISSN: 0269-5545
URL: http://www.defra.gov.uk/animalh/gvj/default.htm
Descriptors: cattle, Mycobacterium bovis, modeling of disease distribution, zoonotic infections, Great Britain.
Mobius, P.; Lentzsch, P.; Moser, I.; Naumann, L.; Martin, G.; Kohler, H. Comparative macrorestriction and RFLP analysis of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuis isolates from man, pig, and cattle. Veterinary Microbiology. 2006 Oct 31; 117 (2-4): 284-291. ISSN: 0378-1135
URL: http://dx.doi.org/10.1016/j.vetmic.2006.05.005
NAL Call Number: SF601.V44
Abstract: In Germany, tuberculous lesions in slaughtered pigs due to infection with members of the Mycobacterium avium complex are increasingly reported. Contaminated food originating from pig or other livestock is discussed as potential source of human infection. M. avium isolates from man (n = 45), pig (n = 29), and cattle (n = 13) were characterised by restriction fragment length polymorphism (RFLP) with respect to insertion sequences IS1245 and IS901 as well as by XbaI-based pulsed-field gel electrophoresis (PFGE) and the results were compared by computer cluster correlation analysis, to determine potential sources of infection in man. By PCR, 55% of animal isolates was identified as M. avium subsp. avium, and 45% as M. a. hominissuis. All human isolates belonged to M. a. hominissuis. IS1245-RFLP and PFGE resulted in two distinct main groupings reflecting the two subspecies, and dividing the isolates into several subgroups. Animal isolates of M. a. hominissuis were widely distributed within the subgroups of human isolates. M. a. avium isolates, further discriminated by IS901-RFLP, formed host-associated subgroups for animals. Comparison of RFLP patterns with those of PFGE resulted in different subgroups as well as different pairs of isolates with high similarities. Only two isolates exhibited identical patterns by both methods. In general, results of both methods support the possibility that M. a. hominissuis isolates from livestock represent a source of infection for man, probably by common environmental reservoirs. There was no evidence of human infections caused by M. a. avium in Germany.
Descriptors: pigs, humans, Mycobacterium avium avium, Mycobacterium avium hominissuis, bacterial isolates, zoonotic tb strains, food contamination, RFLP characterization, Germany.
Moda, G. Non-technical constraints to eradication: the Italian experience. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 253-258. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: Although technical constraints to eradication of bovine tuberculosis are well-recognized, non-technical constraints can also delay progress towards eradication, leading to inefficiency and increased programme costs. This paper seeks to analyze the main non-technical constraints that can interfere with the successful implementation of tuberculosis eradication plans, based on experiences from an area of high tuberculosis prevalence in Regione Piemonte, Italy. The main social and economic constraints faced in the past 20 years are reviewed, including a social reluctance to recognize the importance of seeking eradication as the goal of disease control, effective communication of technical issues, the training and the organization of veterinary services, the relationship between the regional authority and farmers and their representatives, and data management and epidemiological reporting. The paper analyses and discusses the solutions that were applied in Regione Piemonte and the benefits that were obtained. Tuberculosis eradication plans are one of the most difficult tasks of the Veterinary Animal Health Services, and non-technical constraints must be considered when progress towards eradication is less than expected. Organizational and managerial resources can help to overcome social or economic obstacles, provided the veterinary profession is willing to address technical, but also non-technical, constraints to eradication.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control, disease control programs, disease prevalence, pathogen eradication, economic analysis, economic costs, social behavior, social barriers, veterinarians, social environment, Italy.
Monies, R.J. Tuberculous pneumonia and BVD in housed calves. GVJ-Government Veterinary Journal. 2006; 16 (1): 81-86. ISSN: 0269-5545
URL: http://www.defra.gov.uk/animalh/gvj/default.htm
Descriptors: calves, cattle, disease levels, bovine diarrhea virus, BVD, cattle, Mycobacterium bovis, postmortem inspections, autopsy reports, clinical picture, mucosal diseases, multiple infections, death rates, United Kingdom.
More, S.J.; Collins, J.D.; Gormley, E.; Good, M.; Skuce, R.A.; Pollock, J.M. Proceedings of the 4th International Conference on Mycobacterium bovis, Dublin, Ireland, 22-26 August 2005. Veterinary Microbiology. 2006; 112 (2/4): 89-391. ISSN: 0378-1135. Note: Special issue: S.J. More; J.D. Collins; E. Gormley; M. Good; R.A. Skuce; J.M. Pollock (editors). Proceedings of the 4th International Conference on Mycobacterium bovis, Dublin, Ireland, 22-26 August 2005.
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Descriptors: humans, livestock domestic animals, cattle, wild animals, Mycobacterium bovis, diagnosis, epidemiology, zoonotic disease prevalence, pathogenesis, diagnosis and control, vaccination, animal reservoirs, vaccine development.
More, S.J.; Collins, J.D.; Gormley, E.; Good, M.; Skuce, R.A.; Pollock, J.M. 4th International Conference on Mycobacterium bovis: workshop reports. Veterinary Microbiology. 2006; 112 (2/4): 383-391. ISSN: 0378-1135. Note: Special issue: S.J. More; J.D. Collins; E. Gormley; M. Good; R.A. Skuce; J.M. Pollock (editors). Proceedings of the 4th International Conference on Mycobacterium bovis, Dublin, Ireland, 22-26 August 2005.
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Descriptors: conference workshop reports, policy, strategy, Mycobacterium bovis, disease control, disease eradication programs, diagnosis, molecular epidemiology, wild animals as disease reservoirs, vaccines, vaccination of animals, cattle, livestock.
More, S.J.; Good, M. The tuberculosis eradication programme in Ireland: a review of scientific and policy advances since 1988. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 239-251. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: A national programme to eradicate bovine tuberculosis commenced in Ireland in 1954. During the last 15-20 years, research has been conducted to address gaps in knowledge of disease epidemiology, to objectively evaluate alternative strategy options, and to critically assess the implementation of disease control strategies. This paper provides a review of scientific and policy advances in Ireland since 1988, relevant to the tuberculosis eradication programme in Ireland. There have been substantial advances in knowledge of aspects of disease epidemiology, relating to cattle-to-cattle transmission, the role of wildlife, transmission of infection from wildlife and methods to minimise wildlife-to-cattle transmission. Further, scientific advances have been made both in the detection and management of infected herds. With respect to policy, the paper describes current policy and policy advances in both the detection and management of infected herds, as well as current strategies to prevent herd breakdowns. The Irish programme is a useful example of science-informed policy in a national context.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, disease control, disease control programs, disease surveillance, disease outbreaks, culling animals, wildlife, animal diseases, tuberculosis, disease reservoirs, diagnosis, disease transmission, pathogen identification, pathogen eradication, literature reviews, agricultural policy, Irish Republic.
Mores, N.; Amaral, A.L.; Ventura, L.; Silva, R.A.M.; Silva, V.S.; Barioni-Junior, W. Comparacao entre metodos de tuberculinizacao no diagnostico da infeccao por agentes do complexo Mycobacterium avium ou M. bovis em suinos. [Comparative study of methods of tuberculin skin test with the avium and bovine tuberculin in the diagnosis of the infection by agents of the Mycobacterium avium-complex or M. bovis in swine.] Arquivo Brasileiro de Medicina Veterinaria e Zootecnia. 2006; 58 (5): 708-717. ISSN: 0102-0935. Note: In Portuguese with an English summary.
NAL Call Number: SF604.A76
Descriptors: hogs, swine, naturally and experimentally infected hogs, tuberculin skin test with avian and bovine PPD, detection of pathogen, skin readings compared to gross lesions and histological changes in lymph nodes, diameter of reaction.
Mustafa, A.S.; Skeiky, Y.A.; Al Attiyah, R.; Alderson, M.R.; Hewinson, R.G.; Vordermeier, H.M. Immunogenicity of Mycobacterium tuberculosis antigens in Mycobacterium bovis BCG-vaccinated and M. bovis-infected cattle. Infection and immunity (IAI). 2006 Aug.; 74 (8): 4566-4572. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1.I57
Abstract: The development of novel vaccine strategies supplementing Mycobacterium bovis BCG (BCG) constitutes an urgent research challenge. To identify potential subunit vaccine candidates, we have tested a series of eight recently identified Mycobacterium tuberculosis antigens in M. bovis-infected and BCG-vaccinated cattle. These antigens were characterized on the basis of their ability to induce in vitro gamma interferon responses in infected or BCG-vaccinated calves. We were able to establish a hierarchy of these antigens based on how frequently they were recognized in both groups of animals. In particular, we were able to prioritize frequently recognized proteins like Rv0287, Rv1174, and Rv1196 for future evaluation as subunit vaccines to be used in BCG-protein heterologous prime-boost vaccination scenarios. In addition, the antigen most dominantly recognized in M. bovis-infected cattle in this study, Rv3616c, was significantly less frequently recognized by BCG vaccinees and could be a target to improve BCG, for example, by increasing its secretion, in a recombinant BCG vaccine.
Descriptors: cattle, vaccines, subunit vaccine candidates, eight Mycobacterium tuberculosis antigens, Mycobacterium bovis-infected and BCG-vaccinated cattle, Rv3616c antigen.
Nassar, A.F.de C.; Roxo, E.; Portugal, M.A.da S.C. Revisao: tuberculose genital em bovinos e bubalinos. [Review: genital tuberculosis in cattle and water buffaloes.] Revista de Educacao Continuada do CRMV-SP. 2005; 8 (2): 135-144. ISSN: 1516-3326. Note: In Portuguese with English and Spanish summaries.
Descriptors: cattle, water buffalo, Mycobacterium bovis, genital tuberculosis, endometritis, incidence over 30 years, economic impact, zoonotic disease public health concern, contaminated raw milk and cheese, bovine mastitis, complications, disease prevalence; epidemiology, Sao Paulo, Brazil.
Nishath Latheef; Ganesan, P.I. Haematological and biochemical parameters in tuberculin reactor and non reactor cattle. Indian Veterinary Journal. 2006; 83 (8): 918-919. ISSN: 0019-6479
URL: www.indvetjournal.com
NAL Call Number: 41.8 IN2
Descriptors: cattle, Mycobacterium bovis, intradermal tuberculin test reactions, description of positive reaction, hematology of test reactors, blood cell counts, hemoglobin, hematocrit, serum biochemistry, clinical responses.
Nishi, J.S.; Shury, T.; Elkin, B.T. Wildlife reservoirs for bovine tuberculosis (Mycobacterium bovis) in Canada: strategies for management and research. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4) 325-338. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: In Canada, there are two known regional foci where wildlife populations are infected with bovine tuberculosis (Mycobacterium bovis) and considered to be disease reservoirs. Free-ranging populations of wood bison (Bison bison athabascae) in and around Wood Buffalo National Park (WBNP) and wapiti (Cervus elaphus manitobensis) in and around Riding Mountain National Park (RMNP) are infected with bovine tuberculosis. In this paper, we provide an overview of these diseased wild ungulate populations and the complexities of attempting to manage issues relating to bovine tuberculosis in and around protected areas. We do not describe the quantitative science and epidemiological data in detail from these case histories, but instead compare and contrast these two cases from a broader perspective. This is achieved by reviewing the context and process by which a diverse group of stakeholders engage and develop strategies to address the controversial problems that diseased wildlife populations often present. We suggest that understanding the factors that drive the strategic-level management processes is equally important for addressing a wildlife disease problem as the tactical-level issues, such as design and implementation of technically sound field research and management programs. Understanding the experiences within the WBNP and RMNP areas, particularly the strategies that have failed or succeeded, may prove useful to understanding and improving management approaches when wildlife are infected with M. bovis. Applying this understanding is consistent with the principles of adaptive management in which we learn from previous experiences to develop better strategies for the future.
Descriptors: cattle, food animals, Mycobacterium bovis, wood bison (Bison bison athabascae), Wood Buffalo National Park, wapiti (Cervus elaphus manitobensis), Riding Mountain National Park, diseased wild ungulate populations, disease management issues in protected areas, how to approach strategic level management processes, disease vectors, disease transmission, control programs, literature reviews, wildlife management, wild animals, wildlife, animal diseases, tuberculosis, alternative hosts, disease outbreaks, disease transmission, conservation areas, case studies, disease control programs, disease reservoirs, Alberta, Canada.
O'Brien, D.J.; Schmitt, S.M.; Fitzgerald, S.D.; Berry, D.E.; Hickling, G.J. Managing the wildlife reservoir of Mycobacterium bovis: The Michigan, USA, experience. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4) 313-323. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: Historical, social and economic factors combined to provide a focus where bovine tuberculosis has become established in free-ranging wildlife in northeastern lower Michigan. White-tailed deer, the primary reservoir and maintenance host of tuberculosis, are highly valued by the public, and particularly hunters, for cultural and economic reasons. Since 1995, significant progress has been made in defining and reducing the reservoir of tuberculosis in deer. As yet, no other wildlife species has been shown to play an epidemiologically important role in the disease cycle. The importance of deer and deer hunting to Michigan has uniquely shaped tuberculosis control policies, and poses ongoing challenges as wildlife managers strive to maintain momentum for broad control strategies, and develop focused strategies that are publicly acceptable. Even if momentum and funding can be maintained, tuberculosis will likely continue to be present for a decade or longer. Thus, cattle producers waiting for tuberculosis to be eradicated from wildlife to eliminate risks to their herds and markets face disappointment for the foreseeable future. Such unrealistic expectations also place Michigan's federal tuberculosis accreditation status at perpetual risk. Accredited free status is unlikely to be regained without accompanying changes in cattle management. In Michigan, management of tuberculosis has clearly demonstrated that social issues and public approval are likely to be the critical limiting factors in control.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, wildlife management, deer, wild animals, wildlife, tuberculosis, alternative hosts, disease outbreaks, disease transmission, case studies, social barriers, public opinions, sport hunting, disease control programs, disease control programs, disease reservoirs, Michigan.
Olea-Popelka, F.; Butler, D.; Lavin, D.; McGrath, G.; O'Keeffe, J.; Kelton, D.; Berke, O.; More, S.; Martin, W. A case study of bovine tuberculosis in an area of County Donegal, Ireland. Irish Veterinary Journal. 2006; 59 (12): 683-690. ISSN: 0368-0762
URL: www.veterinary-ireland.org
Descriptors: cattle, badgers, disease level, herd to herd transmission, bovine tuberculosis, Mycoabacterium bovis, animal disease control-programs, Eire, Irish Republic.
Olea-Popelka, F.J.; Phelan,.J.; White, P.W.; McGrath, G; Collins, J.D.; O'.Keeffe, J.; Duggan, M.; Collins, D.M.; Kelton,-DF; Berke, O. Quantifying badger exposure and the risk of bovine tuberculosis for cattle herds in county Kilkenny, Ireland. Preventive Veterinary Medicine. 2006 July 17; 75 (1-2): 34-46. ISSN1: 0167-5877
URL: http://dx.doi.org/10.1016/j.prevetmed.2006.01.014
NAL Call Number: SF601.P7
Descriptors: cattle, cattle diseases, bovine tuberculosis, Mycobacterium bovis, epidemiological studies, disease transmission, wildlife, disease reservoirs, badgers, Meles meles, risk assessment, wildlife livestock relations, pastures, cattle grazing, cattle housing, herd health, disease incidence, quantitative analysis, Irish Republic.
Oloya, J.; Opuda-Asibo, J.; Djonne, B.; Muma, J.B.; Matope, G.; Kazwala, R.; Skjerve, E. Responses to tuberculin among Zebu cattle in the transhumance regions of Karamoja and Nakasongola district of Uganda. Tropical Animal Health and Production. 2006 May; 38 (4): 275-283. . ISSN: 0049-4747
URL: http://dx.doi.org/10.1007/s11250-006-4322-7
NAL Call Number: SF601.T7
Descriptors: zebu, seroprevalence, bovine tuberculosis, risk factors, drinking water, dry season, Mycobacterium bovis, transhumance regions, skin tests, zoonoses, Uganda.
Palmer, M.V.; Waters, W.R. Advances in bovine tuberculosis diagnosis and pathogenesis: what policy makers need to know. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4) 181-190. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: The mainstay of tuberculosis diagnosis in cattle and deer has been the tuberculin skin test. Recent advances have allowed the incorporation of blood based assays to the diagnostic arsenal for both cattle and deer. Use of defined and specific antigens has allowed for improved specificity of cell mediated assays in both cattle and deer and advances in antibody tests for tuberculosis have potential for use in free-ranging and captive cervid populations. Combined use of blood-based assays with skin testing will require further understanding of the effect of skin testing on the accuracy of blood based assays. Models of experimental infection of cattle have allowed for increased understanding of natural disease pathogenesis. Differences likely exist; however, between cattle and deer in both disease distribution and primary route of inoculation in naturally infected animals.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease diagnosis, pathogenesis, disease course, agricultural policy, health policy, zoonoses, diagnostic techniques, deer, wild animals, animal diseases, tuberculosis, disease transmission, epidemiology, interferons, tuberculin, bacterial antigens.
Palmer, M.V.; Waters, W.R.; Thacker, T.C.; Greenwald, R.; Esfandiari, J.; Lyashchenk, K.P. Effects of different tuberculin skin-testing regimens on gamma interferon and antibody responses in cattle experimentally infected with Mycobacterium bovis. Clinical and Vaccine Immunology. 2006; 13 (3): 387-394. ISSN: 1556-6811
URL: http://cvi.asm.org/
NAL Call Number: RB46.5
Descriptors: Holstein calves, experimental infection, Mycobacterium bovis, whole blood cellular immunoassay, bovine game interferon, INF gamma, comparative cervical test, caudal fold test, timing of testing may affect results.
Pavlik, I. The experience of new European Union Member States concerning the control of bovine tuberculosis. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 221-230. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: On 1 May 2004, 10 new States joined the European Union, including Cyprus (CY), the Czech Republic (CR), Estonia (ES), Hungary (HU), Latvia (LA), Lithuania (LI), Malta (MA), Poland (PO), Slovakia (SK), and Slovenia (SN). Using OIE and published data, this paper summarizes the status of bovine and human tuberculosis in animals in these countries between 1996 and 2003. National control programmes against bovine tuberculosis in cattle have been successful: the current herd incidence of this disease in cattle is currently lower than 0.2%, so all countries meet the OIE requirements for freedom from the disease. Furthermore, two countries have already been officially declared bovine tuberculosis-free EU States: the CR on 31 March 2004 (European Commission Decision No. 2004/320/EC) and SK on 4 March 2005 (Commission Decision No. 2005/179/EC). The last outbreak of bovine tuberculosis was diagnosed in cattle in CY (1928), ES (1986), LA (1989), SK (1993), CR (1995), and MA (2001). However, several issues of concern remain including the potential existence of a wildlife reservoir, the presence of Mycobacterium bovis, M. caprae, and other members of the M. tuberculosis complex (particularly M. tuberculosis or M. microti) in imported domestic or wild animals, and the potential for delayed detection of bovine tuberculosis in those States where annual tuberculin testing is no longer performed on cattle older than 24 months.
Descriptors: cattle, Mycobacterium bovis, Mycobacterium bovis, Mycobacterium caprae, members of the Mycobacterium tuberculosis complex (particularly Mycobacterium tuberculosis, ycobacterium microti), animal pathogenic bacteria, bovine tuberculosis, disease control, disease control programs, humans, tuberculosis, zoonoses, disease incidence, herd health, disease outbreaks, wildlife, animal diseases, disease diagnosis, disease surveillance, disease reservoirs, European Union.
Pereira-Suarez, A.L.; Estrada-Chavez, C.; Arriaga-Diaz, C.; Espinosa-Cueto, P.; Mancilla, R. Coexpression of NRAMP1, iNOS, and nitrotyrosine in bovine tuberculosis. Veterinary Pathology. 2006; 43 (5): 709-717. ISSN: 0300-9858
URL: http://www.acvp.org
NAL Call Number: 41.8 P27
Abstract: In murine models the inducible nitric oxide synthase (iNOS) and the natural resistance associated macrophage protein (NRAMP1) play major roles in host defence against mycobacteria. iNOS regulates nitric oxide (NO) production, which is noxious for ingested mycobacteria, and NRAMP1 displays pleiotropic antimicrobial effects, including upregulation of iNOS expression. Little is known about the role of these molecules in bovine tuberculosis (TB). In this work we demonstrate by Western blot a high expression of NRAMP1 in peripheral blood mononuclear cells (PBMCs), alveolar macrophages (obtained by bronchioalveolar lavage), and lymph node granulomas from 8 Holstein-Freisian cattle with autopsy-proven bovine TB. Immunohistochemistry revealed the abundant expression of NRAMP1 and iNOS in lymph node and lung granulomas. Immunoreactivity was abundant in the cytoplasm of many epithelioid macrophages and multinucleated giant cells of the Langhans type. A striking accumulation of nitrotyrosine (NT), an indicator of iNOS activity and local NO production, was observed in granuloma cells, particularly in multinucleated Langhans cells. This study shows that the expression of NRAMP1 and iNOS is costimulated in granulomas, which are protective T-cell reactions against mycobacteria..
Descriptors: Holstein-Freisian cattle, murine model, lymph node granulomas, T cells, nitric oxide synthase; nitrotyrosine Mycobacterium bovis.
Perrin, G.; Heraud, J.L. Patologie dei piccoli ruminanti la diagnosi della tubercolosi nei caprini. [Diagnosis of tuberculosis in goats.] Summa, Animali da Reddito. 2006; 1 (2): 45-48. ISSN: 1125-6745. Note: In Italian.
Descriptors: goats, diagnosis of TB, Mycobacterium bovis, disease surveillance, Italy.
Pfeiffer, D.U. Communicating risk and uncertainty in relation to development and implementation of disease control policies. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4) 259-264. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: Scientific evidence is one of the key factors to be considered in the development of disease control policies. It is generated using investigations into cause-effect relationships, which usually produce results that are associated with a varying degree of uncertainty. Experience has shown that taking account of these uncertainties can become a formidable challenge for policy makers when devising the strategies and when communicating them to stakeholders. The situation has been further complicated by a reduction in public trust in scientific evidence. It is now recognized that this challenge cannot be managed by simply providing more information, but it is also necessary to consider the influence that variation in risk perception amongst stakeholders has on their response to and commitment towards the policies.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control programs, disease prevalence, risk assessment, agricultural policy, health policy, communication human, public opinion, risk communication, consumer information, scientific evidence.
Proano-Perez, Freddy; Rigouts, Leen; Brandt, Jef; Dorny, Pierre; Ron, Jorge; Chavez, Maria Augusta; Rodriguez, Richar; Fissette, Krista; Van Aerde, Anita; Portaels, Francoise; Benitez-Ortiz, Washington. Preliminary observations on Mycobacterium ssp in dairy cattle in Ecuador. American Journal of Tropical Medicine and Hygiene. 2006; 75(2): 318-323.
URL: www.ajtmh.org
Descriptors: bovine tuberculosis, dairy cattle production, 1,012 cattle, 59 farms, tuberculin test, comparative tuberculin test, slaughter house tissue, Mycobacterium bovis, effect of dairy herd size, Mejia canton, Ecuador.
Proud, A.J. Some lessons from the history of the eradication of bovine tuberculosis in Great Britain. GVJ-Government Veterinary Journal. 2006; 16 (1): 11-18. ISSN: 0269-5545
URL: http://www.defra.gov.uk/animalh/gvj/default.htm
Descriptors: cattle. Mycobacterium bovis, history of eradication programs, lessons learned, disease distribution, zoonotic infections, Great Britain.
Radunz, B. Surveillance and risk management during the latter stages of eradication: experiences from Australia. Veterinary Microbiology. 2006 Feb 25; 112(2-4): 283-290. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Abstract: The paper reviews the eradication of bovine tuberculosis from Australia with special reference to surveillance and managing the risk of animals exposed to tuberculosis infected animals during the latter stages of eradication. The successful eradication was based on a sound technical program with strong industry and government support. The model of joint industry and government funding and decision-making first used during the brucellosis and tuberculosis eradication campaign (BTEC) has been successfully incorporated within subsequent livestock disease control programs in Australia. An overview of the history of tuberculosis eradication in Australia provides a background to the surveillance approach. Australia was fortunate that there were no wildlife reservoir hosts. Feral animal reservoir hosts were removed during the eradication program. Surveillance to detect rare diseases is recognized to be statistically challenging with high resource requirements. Australian veterinary authorities have a high level of confidence that the combination of increasing sensitivity of abattoir surveillance systems by the submission of all granulomas detected at slaughter with increasing risk management of animals exposed to tuberculosis infected animals during the final stages of eradication provides a high level of assurance that Mycobacterium bovis has been eradicated.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control programs, disease outbreaks, disease transmission, risk management, disease surveillance, decision making, agricultural history, wildlife, animal diseases, tuberculosis, disease reservoirs, slaughterhouses, meat inspection, pathogen eradication, culling animals, Australia
Ramirez-Casillas, I.C.; Santillan-Flores, M.A.; Arellano-Reynoso, B.; Morales-Alvarez, F.; Tenorio-Gutierrez,V.R. Detection of Mycobacterium bovis nucleotide sequences from nasal mucus of experimentally inoculated goats. Veterinaria Mexico. 2006; 37 (2): 191-196. ISSN: 0301-5092. Note: In English and Spanish.
URL: http://www.medigraphic.com/veterinariamexico/
NAL Call Number: SF604.V485
Descriptors: goats, fast reliable molecular method for Mycobacterium bovis, field application, M-PCR technique, detecting bacterial pathogen DNA in mucus, experimental infection, experimental transmission, immunity reactions, immunological reactions.
Reviriego-Gordejo, F.J.; Vermeersch, J.P. Towards eradication of bovine tuberculosis in the European Union. An update on bovine tuberculosis programmes in Latin American and Caribbean countries. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 101-109. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Abstract: This paper reviews the developments and progress towards eradication of bovine tuberculosis in the European Union (EU). A historical view of the EU legislation aimed at mainly approximating provisions on intra-community in cattle trade explains the present EU policies. The variety of cattle breeding systems and environmental conditions in the EU leads to different epidemiological situations. The current situation of bovine tuberculosis in the EU Member States is summarized, and current policy in the EU is outlined.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, international trade, disease control, disease control programs, quarantine, literature reviews, European Union, epidemiology, agricultural policy, pathogen eradication, Europe.
Reynolds, D. TB policy developments. GVJ-Government Veterinary Journal. 2006; 16 (1): 5-10. ISSN: 0269-5545
URL: http://www.defra.gov.uk/animalh/gvj/default.htm
Descriptors: cattle. Mycobacterium bovis, badgers (Meles meles), eradication and control programs, lessons learned, disease distribution, zoonotic infections, UK.
Reynolds, D. A review of tuberculosis science and policy in Great Britain. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4) 119-126. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Abstract: Bovine tuberculosis is one of the most complex animal health problems that the farming industry in Great Britain faces today. In leading and facilitating the changes to policy required to reverse the long-term upward trend in the disease, Government is heavily reliant on evidence emerging from its wide-ranging bovine tuberculosis research programme. The paper outlines development of policy in Great Britain and its relationship to research findings.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, disease control, disease control programs, literature reviews, disease incidence, disease outbreaks, agricultural research, information sources, Great Britain.
Rishendra Verma; Samir Das. Zoonotic tuberculosis due to Mycobacterium bovis in India. Intas Polivet. 2006; 7 (2): 227-235. ISSN: 0972-1738
Descriptors: zoonotic tuberculosis, Mycobacterium bovis, Mycobacterium tuberculosis, economic losses, humans, animals, wildlife, diagnosis, clinical picture, antiobiotic treatment, disease surveillance, zoonotic infections, India.
Romero, B.; Bezos, J.; Alvarez, J.; Aranaz, A.; Juan, L. de; Lozano, F.; Mateos, A.; Dominguez, L.; Travnicek, M. Bovinna tuberkuloza v EU - pritomnost a buducnost. [Bovine tuberculosis in EU - the presence and future.] Slovensky Veterinarsky Casopis. 2006; 31 (3): 165-168. ISSN: 1335-0099. Note: In Slovakian.
Descriptors: cattle, Mycobacterium bovis, Common Market, EC; EEC; European Communities, European Economic Communities.
Romero-Tejeda, Aurora; Arriaga-Diaz, Camila; Guevara-Vivero, Jesus; Garcia-Salazar, Jose Alfredo; Torres-Leon, Ruben Arturo; Estrada-Chavez, Ciro. Confirmacion de la excrecion de Mycobacterium bovis en exudados nasales mediante PCR anidada en un hato lechero. [Confirmation of Mycobacterium bovis excretion in nasal exudates using nested PCR in a dairy cattle herd.] Veterinaria Mexico. 2006; 37(1): 137-143. ISSN: 0301-5092. Note: In Spanish.
URL: http://medigraphic.com/ingles/i-htms/i-vetmex/im-vm.htm
NAL Call Number: SF604.V485
Descriptors: dairy cattle, disease transmission, Mycobacterium bovis, respiratory excretion of bacteria and relationship with immune response, nasal exudates analyzed, nested PCR, IFN gamma.
Rosseels, Valerie; Marche, Sylvie; Roupie,Virginie; Govaerts, Marc; Godfroid, Jacques; Walravens, Karl; Huygen, Kris. Members of the 30- to 32-kilodalton mycolyl transferase family (Ag85) from culture filtrate of Mycobacterium avium subsp. paratuberculosis are immunodominant Th1-type antigens recognized early upon infection in mice and cattle. Infection and Immunity. 2006 Jan; 74 (1): 202-212. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1.I57
Abstract: The characterization of protective antigens is essential for the development of an effective, subunit-based vaccine against paratuberculosis. Surface-exposed and secreted antigens, present abundantly in mycobacterial culture filtrate (CF), are among the well-known protective antigens of Mycobacterium tuberculosis and Mycobacterium bovis. Culture filtrate, prepared from Mycobacterium avium subsp. paratuberculosis ATCC 19698 grown as a surface pellicle on synthetic Sauton medium, was strongly and early recognized in experimentally infected B6 bg/bg beige mice and cattle, as indicated by elevated spleen cell gamma interferon (IFN-[gamma]) secretion and lympho-proliferative responses of peripheral blood mononuclear cells, respectively. Strong proliferative and ex vivo IFN-[gamma] responses against antigen 85 (Ag85) complex (a major protein component from M. bovis BCG culture filtrate) could be detected in cattle as early as 10 weeks after oral M. avium subsp. paratuberculosis infection. Synthetic peptides from the Ag85A and Ag85B components of this complex were strongly recognized, whereas T-cell responses were weaker against peptides from the Ag85C protein. A promiscuous T-cell epitope spanning amino acids 145 to 162 of Ag85B (identical sequence in M. bovis and M. avium subsp. paratuberculosis) was identified in experimentally infected cattle. Finally, young calves, born from cows with confirmed paratuberculosis, demonstrated proliferative responses to purified, recombinant Ag85A and Ag85B from M. avium subsp. paratuberculosis. These results indicate that the M. avium subsp. paratuberculosis Ag85 homologues are immunodominant T-cell antigens that are recognized early in experimental and natural infection of cattle.
Descriptors: cattle, Mycobacterium avium paratuberculosis, Mycobacterium bovis, protective antigens, synthetic Sauton medium, cultural filtrate, experimentally infections, B6 bg/bg beige mice, cattle, elevated spleen cell gamma interferon (IFN-[gamma]) secretion, lympho-proliferative responses of peripheral blood mononuclear cells, Ag85 homologues.
Rua-Domenech, R. de la; Goodchild, T.; Vordermeier, M.; Clifton-Hadley, R. Ante mortem diagnosis of bovine tuberculosis: the significance of unconfirmed test reactors. GVJ-Government Veterinary Journal. 2006; 16 (1): 65-71. ISSN: 0269-5545
URL: http://www.defra.gov.uk/animalh/gvj/default.htm
Descriptors: cattle, Mycobacterium bovis, diagnostic testing, intradermal tests, test reactors, zoonotic diseases.
Rua-Domenech, R.de la. Bovine tuberculosis in the European Union and other countries: current status, control programmes and constrains to eradication. GVJ-Government Veterinary Journal. 2006; 16 (1): 19-45. ISSN: 0269-5545
URL: http://www.defra.gov.uk/animalh/gvj/default.htm
Descriptors: cattle. Mycobacterium bovis, disease levels and distribution, zoonotic infections, control programs, issues limiting eradication, EC, USA, Africa, Canada, New Zealand, EU.
Rua-Domenech, R. de la; Goodchild, A.T.; Vordermeier, H.M.; Hewinson, R.G.; Christiansen, K. H.; Clifton-Hadley, R.S. Ante mortem diagnosis of tuberculosis in cattle: a review of the tuberculin tests, gamma-interferon assay and other ancillary diagnostic techniques. Research in Veterinary Science. 2006; 81 (2): 190-210. ISSN: 0034-5288
URL: http://www.sciencedirect.com/science/journal/00345288
NAL Call Number: 41.8 R312
Descriptors: cattle, Mycobacterium bovis, diagnostic testing, live animals, cellular immunity tests, humoral antibody immunity tests, Mycobacterium bovis, PCR probes, electronic nose technology, sensitivity and specificity issues, eradication by culling skin reactors.
Rudolph, B.A.; Riley, S.J.; Hickling, G.J.; Frawley, B.J.; Garner, M.S.; Winterstein, S.R. Regulating hunter baiting for white-tailed deer in Michigan: biological and social considerations. Wildlife Society Bulletin. 2006; 34 (2): 314-321. ISSN: 0091-7648
URL: http://joomla.wildlife.org/index.php?option=com_content&task=view&id=186&Itemid=248
NAL Call Number: SK357.A1W5
Abstract: Eradication of bovine tuberculosis (TB) from free-ranging white-tailed deer (Odocoileus virginianus) requires mortality rates of infected deer exceed the rate of new infection. Efforts to reduce TB transmission in Michigan, USA, are based on 2 assumptions: (1) deer mortality may be increased through recreational hunting and (2) encounter rates between infected and noninfected deer may be reduced by prohibiting baiting and supplemental feeding. Spatial correlation of TB-infected deer and supplemental feeding sites detected using aerial surveys validated a ban on artificial feeding in Michigan. Similar analysis could not be used to evaluate the effects of a baiting ban because bait distribution was unknown. Furthermore, a ban on deer baiting could confound attempts to increase deer mortality through reduced hunter participation or efficacy. We reviewed the process used to evaluate a strategy for regulating bait use by hunters. This review included an assessment of 5 factors: statewide spatial analysis of apparent TB prevalence, deer intraspecific interactions at bait sites, effects of bait on hunter harvest rates, impacts of disease presence and practice of eradication efforts on hunting participation in the infected area and input from law enforcement personnel. Our analysis suggested that restricting baiting to a limited, consistent region incurred less biological risk than allowing bait to be used statewide and less political risk than a statewide ban..
Descriptors: cattle, white tailed deer (Odocoileus virginianus ), Mycobacterium bovis, feeding wild white tailed deer, transmission of disease, death rates, intraspecific interactions at bait sites, restricting baiting to a consistant region, feeding regulations, Michigan, USA.
Ryan, T.J.; Livingstone, P.G.; Ramsey, D.S.L.; de Lisle, G.W.; Nugent, G.; Collins, D.M.; Buddle, B.M. Advances in understanding disease epidemiology and implications for control and eradication of tuberculosis in livestock: the experience from New Zealand. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 211-219. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: A deteriorating tuberculosis problem in cattle and deer in New Zealand has been halted and then reversed over the last decade. Mycobacterium bovis infection in both wild and domestic animal populations has been controlled. This has been achieved by applying a multi-faceted science-based program. Key features of this have been a comprehensive understanding of the epidemiology of tuberculosis in animals, confidence in sampling wild animal populations, effective application of diagnostic tests in cattle and deer, and the ability to map M. bovis genotypes.
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control, disease control programs, deer, wildlife, animal diseases, tuberculosis, disease transmission, disease surveillance, diagnostic techniques, disease diagnosis, genotype, microbial genetics, strains, strain differences, pathogen eradication, serodiagnosis, New Zealand.
Sarma, K.K.; Bhawal, A.; Yadav, V.K.; Saikia, G.; Jogiraj Das. Investigation of tuberculosis in captive Asian elephants of Assam vis-a-vis its cross infections with the handlers. Intas Polivet. 2006; 7 (2): 269-274. ISSN: 0972-1738
Descriptors: Elephas maximus, disease screening, serum testing, indirect hemagglutination test (IHA), Mycobacterium, chemotherapy, clinical picture, disease surveillance, isonicotinic acid hydrazide, zoonotic infections, cross infection with human handlers, antibiotic treatment, isoniazid, streptomycin, Assam, India.
Scantlebury, M.; Harris, S.; Allcroft, D.J.; Hutchings, M.R. Individual trade-offs between nutrition and risk of interspecific transmission of disease by grazing: cows, badger latrines and bovine tuberculosis. Behaviour. 2006; 143 (2): 141-158.
URL: www.brill.nl
Descriptors: bovine-tuberculosis, badgers (Meles meles), cattle, Mycobacterium bovis, cattle behaviors, dairy cows, use of pastures, correlations with physiological states, disease transmission from pastures, badger excreta, milk levels, differences in cattle behavior with just badger urine alone, disease risks, UK.
Scott-Park, F.; Biggs, A. Premovement testing for bovine TB. Veterinary Record (London) . 2006; 158 (16): 571. ISSN: 0042-4900. Note: Correspondence.
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: cattle, Mycobacterium bovis, predicting bovine TB movement, England, UK.
Semret, M.; Bakker, D.; Smart, N.; Olsen, I.; Haslov, K.; Behr, M.A. Genetic analysis of Mycobacterium avium complex strains used for producing purified protein derivatives. Clinical and Vaccine Immunology. 2006; 13 (9): 991-996. ISSN: 1556-6811
URL: http://cvi.asm.org/
Abstract: For over a century, purified protein derivatives (PPD) have been used to detect mycobacterial infections in humans and livestock. Among these, reagents to detect infections by Mycobacterium avium complex organisms have been produced, but the utility of these reagents has not been clearly established due in part to limited biologic and immunologic standardization. Because there is little information about the strains used to produce these reagents (avian PPD, intracellulare PPD, scrofulaceum PPD, and Johnin), we have performed genetic characterizations of strains used to produce these products. Sequence analysis of 16S rRNA and the hsp65 gene provided results concordant with species designations provided for M. avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum organisms. For M. avium strains, comparative genomic hybridization was performed on a whole-genome DNA microarray, revealing one novel 7.9-kilobase genomic deletion in certain Johnin-producing strains, in addition to genomic variability inherent to the particular M. avium subspecies. Our findings indicate that considerable genomic differences exist between organisms used for reagents and the infecting organism being studied. These results serve as a baseline for potency studies of different preparations and should aid in comparative studies of newly discovered antigens for the diagnosis of infection and disease by M. avium complex organisms.
Descriptors: humans, livestock, diagnostic testing, genetic characterizations of strains used for PPD, Mycobacterium avium, Mycobacterium intracellulare.
Shitaye, J. E.; Getahun, B.; Alemayehu, T.; Skoric, M.; Treml, F.; Fictum, P.; Vrbas, V.; Pavlik, I. A prevalence study of bovine tuberculosis by using abattoir meat inspection and tuberculin skin testing data, histopathological and IS6110 PCR examination of tissues with tuberculous lesions in cattle in Ethiopia. Veterinarni Medicina. 2006; 51 (11): 512-522.
URL: http://www.vri.cz/docs/vetmed/51-11-512.pdf
NAL Call Number: 41.9 C333
Descriptors: cattle, goats, sheep, Mycobacterium bovis, 10 year study, trends, tubercular lesions, abattoirs, prevalence levels, Addis Abba, Debre Zeit, Ethiopia.
Shitaye, J.E.; Parmova, I.; Matlova, L.; Dvorska, L.; Horvathova, A.; Vrbas, V.; Pavlik, I. Mycobacterial and Rhodococcus equi infections in pigs in the Czech Republic between the years 1996 and 2004: the causal factors and distribution of infections in the tissues. Veterinarni Medicina. 2006; 51(11): 497-511
URL: http://www.vri.cz/docs/vetmed/51-11-497.pdf
Descriptors: pigs, tuberculous/tuberculoid lesions, distribution of mycobacterial species and Rhodococcus equi in tissues, 3630 slaughtered pigs, microscopic examination and in vitro culture, various organ tissue sampled, gross lesions percentages, disease levels, Czech.
Silva, P.E.G. da; Pinheiro, S.R.; Leal, M.L.do R.; Bertagnon, H.G.; Motta, P.M.P.C.; Sinhorini, I.L.; Vasconcellos, S.A.; Benesi, F.J. Teste de tuberculinizacao em caprinos (Capra hircus) experimentalmente sensibilizados. [Tuberculin test in experimentally sensitized goats (Capra hircus)]. Ciencia Rural. 2006; 36 (3): 880-886. ISSN: 0103-8478. Note: In Portuguese with an English summary.
URL: http://www.scielo.br/scielo.php/script_sci_serial/pid_0103-8478/lng_en/nrm_iso
NAL Call Number: S192.R4
Descriptors: experimentally infected goats, tuberculin skin test, 3 test groups, sensitized with Mycobacterium avium sample D4, sensitized with Mycobacterium bovis sample AN5, saline inoculation control, sample cervical test, diagnostic techniques, skin fold thickness, mononuclear inflammatory infiltrates.
Simion, N. The evolution of bovine tuberculosis incidence in Romania, in the period 2001-2005. Slovenian Veterinary Research. 2006; 43(Supplement 10): 292. Note: Conference proceedings. Edited by B. Zemljic. 7th Middle European Buiatric Congress, Radenci, Slovenia, 29 March-1 April 2006. Veterinarska Fakulteta, Univerza v Ljubljani, Slovenia.
Descriptors: cattle, animal health surveillance, zoonotic diseases, tuberculosis, Mycobacterium bovis, bovine enzootic leucosis, bovine leukemia virus, disease incidence, disease prevalence, disease eradication, epidemiology, Romania.
Singh, A.S.; Pal, D.T. Nutritional status of crossbred cows suffering from mastitis, metritis and tuberculosis. Indian Veterinary Journal. 2006; 83 (7): 748-751. ISSN: 0019-6479
URL: www.indvetjournal.com
NAL Call Number: 41.8 IN2
Descriptors: cattle, crossbred cows, Mycobacterium tuberculosis, mastitis, metritis, tuberculosis, nutritional status of diseased animals vs healthy animals, therapeutic nutrition of sick animals.
Singh, J.P.N.; Rishendra Verma; Chaudhuri, P. Random amplified polymorphic DNA (RAPD) analysis of Mycobacterium bovis strain in India. Indian Journal of Animal Sciences. 2006; 76 (11): 873-877. ISSN: 0367-8318
NAL Call Number: 41.8 IN22
Descriptors: buffalo, cattle, deer, Mycobacterium bovis AN5, M. bovis BCG, 20 field isolates, strain typing, RAPD-PCR, polymorphic amplicons, genetic defects, hereditary defects, heterogeneity, India.
Smith, G.C. Persistence of disease in territorial animals: insights from spatial models of Tb. New Zealand Journal of Ecology. 2006; 30 (1): 35-41. ISSN: 0110-6465
NAL Call Number: QH540.N43
Descriptors: cattle, bovine tuberculosis, wildlife disease transmission, disease, modeling factors, chance, model artifacts, population (e.g. demographic, genetic) heterogeneity, environmental heterogeneity.
Soares-Magalhaes, R.; Smith, N.H.; Dale, J.; Gover, K.; Mitchell, A.; Mawdsley, J.; Stoker, N.G. Investigating the cluster of Mycobacterium bovis spoligotype 13 strains in the southeast of England. Society for Veterinary Epidemiology and Preventive Medicine Proceedings of a Meeting Held at Exeter, UK, 29-31 March 2006. 2006: 215-227. ISBN: 0948073748
Descriptors: cattle, badgers (Meles meles), high concentration of bovine tuberculosis, Mycobacterium bovis isolates, clonal relationships, spoligotype 13, cluster analysis, wildlife as disease reservoirs, East Sussex county England.
Swai, E.S.; Shirima, G.; Bwanga, S.; Moshy, W. Bovine tuberculosis survey in urban and peri urban dairy farms in coastal humid region of Tanga, Tanzania. Bulletin of Animal Health and Production in Africa. 2006; 54 (1): 75-78. ISSN: 0378-9721
NAL Call Number: 41.8 B872
Descriptors: dairy cattle, Mycobacterium bovis, disease surveillance, intradermal comparative tuberculin test, disease prevalence, Tanzania, Tanganyika.
Sweeney, F.P.; Courtenay, O.; Ul Hassan, A.; Hibberd, V.; Reilly, L.A.; Wellington, E.M.H. Immunomagnetic recovery of Mycobacterium bovis from naturally infected environmental samples. Letters in Applied Microbiology. 2006; 43 (4): 364-369. ISSN: 0266-8254
URL: http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=lam
Descriptors: cattle, environmental sampling for Mycobacterium bovis, Mycobacterium bovis BCG, seeded and naturally occurring soil, feces, urine, immunomagnetic capture technique, epidemiological importance of organism in the environment, bovine tuberculosis persistence.
Tadayon, K.; Mosavari, N.; Shahmoradi, A.H.; Sadeghi, F.; Azarvandi, A.; Forbes, K. The epidemiology of Mycobacterium bovis in buffalo in Iran. Journal of Veterinary Medicine B. 2006 Dec; 53 (1): 41-42. ISSN: 0931-1793
URL: http://www3.interscience.wiley.com/journal/118573245/abstract
NAL Call Number: 41.8 Z52
Abstract: Mycobacterium bovis is the cause of bovine tuberculosis (bovine Tb) in animals and is considered to be zoonotic and accordingly it infects humans, although cattle are the main host. Buffalo can also be infected and develop bovine Tb. In Iran, almost half a million buffaloes are farmed, mainly in three provinces. In West Azerbaijan, which has the largest numbers of buffaloes, cattle and buffalo are often farmed together. According to the reports of the Iranian Veterinary Organization over the last 25 years, there have been no reports of bovine Tb in buffalo, although the disease is often reported in cattle in this province. Eighteen and 140 pathology specimens from cattle and buffalo, respectively, collected from West Azerbaijani abattoirs were cultured. From one buffalo specimen out of 140, M. bovis was recovered, whereas the pathogen was isolated from 13 cattle specimens. Spoligotyping showed a relatively higher polymorphism within these isolates compared with M. bovis isolated from other Iranian provinces.
Descriptors: Mycobacterium bovis, cattle, buffalo, epidemiology of the disease, post slaughter survey, West Azerbaijan, Iran.
Tanwar, R.K. Pulmonary tuberculosis in camels (Camelus dromedarius). Veterinary Practitioner. 2006; 7 (1): 17-18. ISSN: 0972-4036
Descriptors: dromedary camels, Mycobacterium, tuberculosis, clinical picture, lung effects, treatment, NSAIDS, sulfamethazine, sulphadimidine, terramycin, Rajasthan, India.
Taylor, C.; Jahans, K.; Palmer, S.; Okker, M.; Brown, J.; Steer, K. Mycobacterium microti isolated from two pigs. Veterinary Record (London). 2006; 159 (2): 59-60. ISSN: 0042-4900
URL: www.bvapublications.com
NAL Call Number: 41.8 V641
Descriptors: 8 month old, sand and black cross bred pigs, Mycobacterium microti UK type 19, Mycobacterium microtum, vole tuberculosis, case report, clinical picture, granuloma lesions, submandibular lymph nodes, multiple PCR, tuberculosis complex, spoligotyping, west Wales, UK.
Thoen, Charles O.; Steele, James H.; Gilsdorf, Michael J. Mycobacterium bovis infection in animals and humans. 2nd ed. Ames, Iowa: Blackwell Pub. 2006. 329 p.: ill., maps. ISBN: 0813809193 (alk. paper)
URL: http://catdir.loc.gov/catdir/toc/ecip0515/2005018463.html
NAL Call Number: RC311.19 .M93 2006
Descriptors: tuberculosis in cattle. Mocobacterium bovis, AIDS disease complications.
Thoen, C.; LoBue, P.; Kantor, I. de. The importance of Mycobacterium bovis as a zoonosis. Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 339-345. ISSN: 0378-1135. Note: Paper presented at the 4th International Conference on Mycobacterium bovis, held August 22-26, 2005, Dublin, Ireland.
URL: www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract: Mycobacterium bovis and closely associated acid-fast bacilli cause disease in humans. Epidemiologic investigations reveal that the organism may be ingested or inhaled. Extra pulmonary lesions may occur associated to the consumption of infected milk, even though with the practice of boiling milk, and the growth of milk pasteurization plants all over the world, the digestive route of infection became less important. On the other hand, airborne infection continues to occur among meat industry and slaughterhouse workers, in regions where the infection is still prevalent in cattle. Evidence of person to person transmission is rare. Main causes of concern related to M. bovis in industrialized countries are: epizootics in domesticated and wild mammals and latent infection in immigrants. Although multi-drug-resistant (MDR) strains of M. bovis have been identified, case reports reveal that anti-tuberculosis drugs routinely used to treat Mycobacterium tuberculosis-infected patients are effective when properly administered.
Descriptors: cattle, food animals, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, zoonoses, humans, tuberculosis, disease transmission, lesions animal, health hazards, occupational health and safety, livestock and meat industry, slaughterhouses, disease outbreaks, wild animals, latent period, multiple drug resistance, asymptomatic infections.
Thom, M.L.; Hope, J.C.; McAulay, M.; Villarreal-Ramos, B.; Coffey, T.J.; Stephens, S.; Vordermeier, H.M.; Howard, C.J. The effect of tuberculin testing on the development of cell-mediated immune responses during Mycobacterium bovis infection. Veterinary Immunology and Immunopathology. 2006 Nov 15; 114 (1-2): 25-36. ISSN 0165-2427
URL: http://dx.doi.org/10.1016/j.vetimm.2006.07.001
NAL Call Number: SF757.2.V38
Abstract: Protection against tuberculosis (TB) is associated with Th1-type cell-mediated immunity (CMI). Whilst the intradermal injection of partially purified derivatives of tuberculin (PPD) represents the classic test assessing the delayed type hypersensitivity (DTH) response used in both humans and cattle for diagnosing TB, it has been suggested that the test may modulate host CMI responses. To investigate the kinetics of the development of the DTH response and its subsequent effect on CMI responses, groups of 6-month old calves were inoculated intranasally with 8 x 10(4) cfu of Mycobacterium bovis, subjected to the comparative intradermal tuberculin test (TT) using bovine and avian PPD (PPD-B, PPD-A) at various time intervals post-infection, and immune responses compared. These included DTH, lymphocyte proliferation, IgG production, and synthesis of the cytokines: IFN(Sd(B, IL-10, IL-4, IL-6, and IL-13. All animals were subjected to post-mortem examination. The kinetics of the development of the DTH response assessed in the TT was such that infected cattle could be identified as early as 3 weeks post-infection, which correlated with the detection of an antigen-specific IFN(Sd(B response. Transient increases in plasma-derived IFN(Sd(B as a result of TT during an established TB infection were more pronounced when blood was stimulated with PPD-A compared with PPD-B stimulation. This has the potential to mask diagnosis of infection as a result of the stronger avian-bias if the IFN(Sd(B test is used the week following TT. Disease pathology was not affected by TT. A transient failure to a second TT was observed in 1 of 30 animals and the time (post-infection) at which the TT is administered may be of significance. In serum, IgG responses to PPD-B, which were undetectable prior to TT, were elevated after TT and were most pronounced in cattle that were TT at 6 weeks post-infection. Other cytokines were also affected by the TT; IL-4 mRNA levels increased and IL-6 mRNA levels decreased, whilst PPD-B specific IL-10 protein synthesis was enhanced. These observations may offer the potential for further diagnostic assays that could complement the TT and IFN(Sd(B test.
Descriptors: 6 month old calves, intranasal inoculation, Mycobacterium bovis, cell mediated immunity, intradermal immunity testing, IFN (Sd(B. cytokines, IL-4mRNA levels increased, IL6 mRNA decreased, PPD-B specific IL-10 protein synthesis enhanced, diagnostic assays.
Twomey, D.F.; Crawshaw,.T.R.; Anscombe,.J.E.; Farrant,.L.; Evans,.L.J.; McElligott, W.S.; Higgins, R.J.; Dean, G.; Vordermeier, M.; Jahans, K.; Rua-Domenech, R. de la. TB in llamas caused by Mycobacterium bovis. Veterinary Record. 2007; 160 (5): 170. ISSN: 0042-4900
URL: http://veterinaryrecord.bvapublications.com/archive/
NAL Call Number: 41.8 V641
Descriptors: llama herd, diagnosis of tuberculosis, Mycobacterium bovis, seroprevalence, antibody tests, intradermal tuberculin test, Devon, UK.
UK Department for Environment Food and Rural Affairs. Special Issue: Bovine TB. GVJ-Government Veterinary Journal. 2006; 16 (1): 91 pp. ISSN: 0269-5545. Note: Special issue contains 10 articles on TB.
URL: http://www.defra.gov.uk/animalh/gvj/default.htm
Descriptors: cattle, other species, Mycobacterium bovis, TB disease levels and distribution, TB policies, disease modeling, Bovigam assay, antemortem diagnosis, tuberculin skin test, zoonotic infections, control programs, issues limiting eradication, EC, USA, Africa, Canada, New Zealand, EU.
Vazquez-Flores, Felicitas; Alonso, Rogelio; Villegas-Sepulveda, Nicolas; Arriaga, Camila; Pereira-Suarez, Ana Laura; Mancilla, Raul; Estrada-Chavez, Ciro. A microsatellite study of bovine solute carrier family 11 a1 (Slc11a1) gene diversity in Mexico in relation to bovine tuberculosis. Genetics and Molecular Biology. 2006; 29 (3): 503-507. ISSN:
URL: http://www.scielo.br/scielo.php?pid=1415-4757&script=sci_serial
NAL Call Number: QH426.R48
Descriptors: cattle, Mycobacterium bovis, genetic susceptibility, polymorphisms, surveyed 34 European, 18 Asian, 20 Creole and 23 hybrid bovines, bovine solute carrier family 11 a1 (Slc11a1) gene, two microsatellite loci closely linked to this gene, levels of heterozygosity, 3' UTR microsatellite locus.
Vengust, G.; Zele, D. Nekatere infekcijske bolezni pri jelenjadi v oborah s poudarkom na zoonozah. [Some infectious diseases of deer in enclosures with emphasis on zoonosis.] Veterinarske Novice. 2006; 32 (3/4): 57-62. ISSN: 0351-5842. Note: In Slovenian with an English summary.
Descriptors: fallow deer, red deer, deer farming, levels of disease, clinical signs, diagnosis, treatment and prevention, Bacillus anthracis, Brucella abortus, Cervus elaphus, Herpesviridae, Leptospira, Listeria monocytogenes, Malignant catarrhal fever virus, Mycobacterium avium ssp paratuberculosis, Mycobacterium bovis, Salmonella, Yersinia pseudotuberculosis, Slovenia.
Vitale, Fabrizio; Reale, Stefano; Petrotta, Enrico; Caracappa, Santo; Barera, Annalisa; La Manna, Marco Pio; Macaluso, Pasquale; Caccamo, Nadia; Dieli, Francesco; Vordermeier, Hans Martin; Sireci, Guido; Salerno, Alfredo. ESAT-6 peptide recognition by bovine CD8(+) lymphocytes of naturally infected cows in herds from southern Italy. Clinical and Vaccine Immunology. 2006; 13 (4): 530-533. ISSN:
URL: http://cvi.asm.org/
NAL Call Number: RB46.5
Descriptors: define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8(+) T lymphocytes from cows naturally infected with Mycobacterium bovis, bovine CD8' T cells recognized 10 out of 11 ESAT-6 peptides tested.
Vordermeier, H.M.; Chambers, M.A.; Buddle, B.M.; Pollock, J.M.; Hewinson, R.G. Progress in the development of vaccines and diagnostic reagents to control tuberculosis in cattle. Veterinary Journal. 2006 Mar; 171 (2): 229-244. ISSN: 1090-0233
URL: http://dx.doi.org/10.1016/j.tvjl.2004.11.001
NAL Call Number: SF601.V484
Abstract: The sharp rise of bovine tuberculosis (TB) in Great Britain and the continuing problem of wild life reservoirs in countries such as New Zealand and Great Britain have resulted in increased research efforts into the disease. Two of the goals of this research are to develop (1) cattle vaccines against TB and (2) associated diagnostic reagents that can differentiate between vaccinated and infected animals (differential diagnosis). This review summarises recent progress and describes efforts to increase the protective efficacy of the only potential TB vaccine currently available, Mycobacterium bovis BCG, and to develop specific reagents for differential diagnosis. Vaccination strategies based on DNA or protein subunit vaccination, vaccination with live viral vectors as well as heterologous prime-boost scenarios are discussed. In addition, we outline results from studies aimed at developing diagnostic reagents to allow the distinction of vaccinated from infected animals, for example antigens that are not expressed by vaccines like Mycobacterium bovis Bacille-Calmette-Guerin, but recognised strongly in Mycobacterium bovis infected cattle.
Descriptors: cattle, bovine tuberculosis,Mycoplasma bovis,drugs, vaccine development, literature reviews, Mycobacterium bovis BCG, BCG vaccine, live vaccines, subunit vaccines, disease detection, analytical methods, reagents, laboratory techniques, immunologic techniques, serodiagnosis, Mycobacterium tuberculosis complex.
Vordermeier, H. Martin; Huygen, Kris; Singh, Mahavir; Hewinson, R. Glyn; Xing, Zhou. Immune responses induced in cattle by vaccination with a recombinant adenovirus expressing mycobacterial antigen 85A and Mycobacterium bovis BCG. Infection and Immunity. 2006 Feb.; 74 (2) 1416-1418. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1.I57
Abstract: Cattle were vaccinated with an adenovirus expressing the mycobacterial antigen 85A (rAd85A), with Mycobacterium bovis BCG followed by rAd85A heterologous boosting, or with rAd85A followed by BCG boosting, BCG/rAd85A resulted in the highest direct gamma interferon responses. Cultured enzyme-linked immunospot assay analysis demonstrated that memory responses were induced by all three protocols but were strongest after BCG/rAd85A and rAd85A/BCG vaccination.
Descriptors: cattle, Mycobacterium bovis BCG, vaccination, adenovirus expressing mycobacterial antigen 85A (rAd85A), 3 protocols, immune response.
Walravens, K.; Allix, C.; Supply, P.; Rigouts, L.; Godfroid, J.; Govaerts, M.; Portaels, F.; Dufey, J.; Vanholme, L.; Fauville-Dufaux, M.; Saegerman, C. Dix annees d'epidemiologie moleculaire de la tuberculose bovine en Belgique. [Ten years of molecular epidemiology of bovine tuberculosis in Belgium.] Epidemiologie et Sante Animale. 2006; (49): 103-111. ISSN: 0754-2186. Note: In French with an English summary.
Descriptors: cattle, Mycobacterium bovis, control and eradication programs, infections sporadic, 10 years of epidemiological data, Belgium.
Ward, A.I.; Tolhurst, B.A.; Delahay, R.J. Farm husbandry and the risks of disease transmission between wild and domestic mammals: a brief review focusing on bovine tuberculosis in badgers and cattle. Animal Science (Penicuik). 2006; 82 (Part 6): 767-773. ISSN: 1357-7298.
URL: http://journals.cambridge.org/action/displayJournal?jid=ASC
Descriptors: wildlife as disease rervoirs, mammals, domesticated animals, disease transmission, European badgers (Meles meles), brushtail possums (Trichosurus vulpecula), culling strategies, changing livestock husbandry, farm management, Mycobacterium bovis, UK.
Waters, W.R.; Palmer, M.V.; Thacker, T.C.; Bannantine, J.P.; Vordermeier, H.M.; Hewinson, R.G.; Greenwald, R.; Esfandiari, J.; McNair, J.; Pollock, J.M.; Andersen, P; Lyashchenko, K.P. Early antibody responses to experimental Mycobacterium bovis infection of cattle. Clinical and Vaccine Immunology. 2006; 13 (6): 648-654. ISSN: 1556-6811 (print). ISSN: 1556-679X (on line)
URL: http://cvi.asm.org/
NAL Call Number: RB46.5
Descriptors: Mycobacterium bovis, zoonotic diease, infected cattle sampling, seroractivity to mycobacterial antigens, experimentalinfection, various inoculation methods, aerosol, intratonsil, intranasal, multiantigen print immunoassay of antigen recognition patterns, immunoblot analysis for sensitive kinetic studies, VetTB STAT-PAK test based on lateral flow technology, MPB83, ESAT-6, CFP-10, and MPB70, rapidity of immune responses, potential of new antibody-based testing.
Waters, W.R.; Palmer, M.V.; Thacker, T.C.; Payeur, J.B.; Harris, N.B.; Minion, F.C. Greenwald, R.; Esfandiari, J.; Andersen, P.; McNair, J.; Pollock, J.M.; Lyashchenko, K.P. Immune responses to defined antigens of Mycobacterium bovis in cattle experimentally infected with Mycobacterium kansasii. Clinical and Vaccine Immunology. 2006; 13 (6): 611-619. ISSN: 1556-6811
URL: http://cvi.asm.org/
NAL Call Number: RB46.5
Descriptors: calves, cross reactivity responses, Mycobacterium bovis, Mycobacterium kansasii, specificity of diagnostic tests, responses of calves shows responses that can confound testing for M. bovis.
Watrelot-Virieux, D.; Drevon-Gaillot, E.; Toussaint, Y.; Belli, P. Comparison of three diagnostic detection methods for tuberculosis in French cattle. Journal of Veterinary Medicine B. 2006; 53 (7): 321-325. ISSN: 0931-1793
URL: http://www3.interscience.wiley.com/journal/118573200/abstract
NAL Call Number: 41.8 Z52
Abstract: Three additional techniques (Ziehl-Neelsen, auramine O/rhodamine and immunostaining using polyclonal anti-Mycobacterium bovis) to hematoxylin-eosin histopathology were evaluated for bovine tuberculosis diagnosis on 39 samples from several slaughterhouses. The immunohistochemical technique was more sensitive and could detect a greater number of positive cattle. It has about the same sensibility as the bacteriology but it was faster.
Descriptors: French cattle, slaughtered animals, Mycobacterium bovis, pathogen detection methods, comparison study, France.
Werling, D.; Piercy, J.; Coffey, T.J. Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells - potential role in pathogen discrimination? Veterinary Immunology and Immunopathology. 2006; 112 (1/2): 2-11. ISSN: 0165-2427
URL: http://www.sciencedirect.com/science/journal/01652427
NAL Call Number: SF757.2.V38
Descriptors: cattle, Mycobacterium, antigenicity, immunogens, B and T lymphocytes, cellular defense mechanisms, immunity reactions, immunological reactions, mRNA, T cells, TOLL-like receptors (TLR), pathogen-associated molecular patterns, TLR2 in host defense against mycobacteria, mycobacteria species-specific response to bovine macrophages.
Winder, C.L.; Gordon, S.V.; Dale, J; Hewinson, R.G.; Goodacre, R. Metabolic fingerprints of Mycobacterium bovis cluster with molecular type: implications for genotype-phenotype links. Microbiology (Reading). 2006; 152 (9): 2757-2765. ISSN: 1350-0872
URL: http://mic.sgmjournals.org
Descriptors: cattle, Mycobacterium bovis, bovine tuberculosis, tracing reservoirs of infection, Fourier-transform infrared spectroscopy (FT-IR), rapid phenotypic typing technique, multivariate cluster analysis, spoligotypes, genotype systematics, Britain, United Kingdom.
Widdison, S.; Schreuder, L.J.; Villarreal-Ramos, B.; Howard, C.J.; Watson, M.; Coffey, T.J. Cytokine expression profiles of bovine lymph nodes: effects of Mycobacterium bovis infection and bacille Calmette-Guerin vaccination. Clinical and Experimental Immunology. 2006; 144 (2): 281-289. ISSN: 0009-9104
URL: http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number: QR180.C5
Descriptors: cattle, experimental infection, intranasal inoculation, comparison with non-inoculated animals, cytokine expression in lymph nodes, vaccination with Mycobacterium bovis BCG, lymph nodes with established tuberculosis and a persisting bacterial infection, maintenance of the pro-inflammatory response in combination with suppressed anti-inflammatory response may control the infection but contribute to host-induced tissue damage.
Woodroffe, R.; Donnelly, C.A.; Cox, D.R.; Bourne, F.J.; Cheeseman, C.L.; Delahay, R.J.; Gettinby, G.; McInerney, J.P.; Morrison, W.I. Effects of culling on badger Meles meles spatial organization: implications for the control of bovine tuberculosis. Journal of Applied Ecology. 2006; 43 (1): 1-10. ISSN: 0021-8901
URL: http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=jpe
NAL Call Number: 410.J828ll
Abstract: The incidence of bovine tuberculosis (TB) in British cattle has risen markedly over the last two decades. Failure to control the disease in cattle has been linked to the persistence of a reservoir of infection in European badgers Meles meles, a nationally protected species. Although badger culling has formed a component of British TB control policy for many years, a recent large-scale randomized field experiment found that TB incidence in cattle was no lower in areas subject to localized badger culling than in nearby areas where no experimental culls occurred. Indeed, analyses indicated that cattle incidence was higher in culled areas. One hypothesis advanced to explain this pattern is that localized culling disrupted badgers' territorial behaviour, potentially increasing the rate of contact between cattle and infected badgers. This study evaluated this hypothesis by investigating badger activity and spatial organization in 13 study areas subjected to different levels of culling. Badger home ranges were mapped by feeding colour-marked baits at badger dens and measuring the geographical area in which colour-marked faeces were retrieved. Badger home ranges were consistently larger in culling areas. Moreover, in areas not subjected to culling, home range sizes increased with proximity to the culling area boundary. Patterns of overlap between home ranges were also influenced by culling. Synthesis and applications. This study demonstrates that culling badgers profoundly alters their spatial organization as well as their population density. These changes have the potential to influence contact rates between cattle and badgers, both where culls occur and on adjoining land. These results may help to explain why localized badger culling appears to have failed to control cattle TB, and should be taken into account in determining what role, if any, badger culling should play in future control strategies..
Descriptors: cattle, badgers (Meles meles), bovine tuberculosis, culling of wild badger, wild animal disease reservoirs, home ranges, increased contact between badgers and cattle, UK.
2005
AAEMA. Journee AEEMA: 20 Mai 2005. AEEMA Meeting, 20 May 2005. Epidemiologie et Sante Animale. 2005; (48): 144 pp. ISSN: 0754-2186. Note: In French. A conference proceedings of 16 papers on infectious diseases in livestock.
Descriptors: pigs, goats, Piedmont cattle breed, sheep, birds, avian influenza virus, bluetongue virus, bovine diarrhea virus, Dermanyssus gallinae, Lawsonia bacteria, Mycobacterium, rabies virus, Salmonella, Toxoplasma, Lawsonia intracellularis, epidemiology, disease contols, clinical picture, Burgundy,Chad, Corsica, France, Italy, Piedmont, South East Asia, West Africa.
Araujo, C.P. de; Leite, C.Q.F.; Prince, K.A. de; Jorge, K. dos S.G.; Osorio, A.L.A.R. Mycobacterium bovis identification by a molecular method from post-mortem inspected cattle obtained in abattoirs of Mato Grosso do Sul, Brazil. Memorias do Instituto Oswaldo Cruz. 2005; 100 (7): 749-752. ISSN: 0074-0276
URL: http://www.scielo.br/scielo.php/script_sci_serial/pid_0074-0276/lng_en/nrm_iso
NAL Call Number: 448.9 IN74
Descriptors: Mycobacterium bovis, bovine tuberculosis, post-slaughter testing, meat quality, contaminated meat products, carcasses with lesions, 23.6 % of samples positive for mycobacteria, Ziehl-Neelsen staining, PCR restriction enzyme patterns, 4 isolates identified, Mato Grosso do Sul, Brazil.
Arpan Maheshwari; Rishendra Verma Evaluation of three antigens by enzyme-linked immunosorbent assay (ELISA) for the detection of Mycobacterium bovis infection in Indian cattle for field use. Indian Journal of Animal Sciences. 2005; 75 (4): 401-406. ISSN: 0367-8318
NAL Call Number: 41.8 IN22
Descriptors: cattle herd testing, sera samples, Mycobacterium bovis, diagnosis, detection, purified protein derivative, protein rich soluble extract, species-specific phenolic glycolipid of Mycobacterium bovis AN5, antigens, ELISA, India.
Asseldonk, M.A.P.M. van; Roermund, H.J.W. van; Fischer, E.A.J.; Jong, M.C.M. de; Huirne, R.B.M. Stochastic efficiency analysis of bovine tuberculosis-surveillance programs in the Netherlands. Preventive Veterinary Medicine. 2005; 69 (1/2): 39-52. ISSN: 0167-5877
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503315/description#description
NAL Call Number: SF601.P7
Descriptors: bovine tuberculosis, stochastic bio-economic model, cost efficient surveillance program, epidemiological module, dynamics of detection, probability of detection, visual examination of carcass lesions at slaughter, GAMMA-interferon testing of blood samples, two state tuberculin testing, future may use ELISA testing of bulk tank milk in combination with slaughter examination, Netherlands.
Baird, G. Caseous lymphadenitis in goats. Goat Veterinary Society Journal. 2005; 21: 21-23. ISSN: 0961-2548
Descriptors: goats, caseous lesions, bacterial pathogens found, Actinobacillus lignieresii, Arcanobacterium pyogenes, Corynebacterium pseudotuberculosis, Mycobacterium, Staphylococcus aureus, Yersinia pseudotuberculosis, UK.
Barrett, D.C. Cattle Review 2005 Parts 41-43. Cattle Practice. 2005; 13 (3): 277-280. ISSN: 0969-1251
NAL Call Number: SF961.C37
Descriptors: cattle, dairy cows, housing, fertility, semen storage, sperm survival, artificial insemination, estrous cycle, hormones, progesterone, reproduction, embryonic development, dry period in dairy cows, nutrition and energy balance, lactation, mammary glands, lameness, estrous cycle, progesterone, reproduction, bovine tuberculosis, Mycobacterium bovis, reviews.
Bernard, F.; Vincent, C.; Matthieu, L.; David, R.; James, D. Tuberculosis and brucellosis prevalence survey on dairy cattle in Mbarara milk basin (Uganda). Preventive Veterinary Medicine. 2005; 67 (4): 267-281. ISSN: 0167-5877
URL: http://www.sciencedirect.com/science/journal/01675877
Descriptors: dairy cattle, Brucella, Mycobacterium bovis, 340 herds tested, intradermal skin test, prevalence survey, age differences, sex differences, breed differences, seroprevalence of pathogens, Mbarara, Uganda.
Bernardelli, A.; Nicola, A.; Alonso, B.; Alonso, Z.; Ulens, K.; Morcillo, N.; Cordero, G.; Cataldi, A.; Zumarraga, M.; Paolicchi, F.; Torres, P.; Kistermann, J.C.; Madero, J.E. Tuberculosis Bovina: evaluacion de tecnicas de diagnostico. [Bovine tuberculosis: evaluation of diagnostic techniques.] Revista de Medicina Veterinaria Buenos Aires. 2005; 86 (5): 183, 194. ISSN: 0325-6391. Note: In Spanish with an English summary.
Descriptors: cattle; Mycobacterium bovis; diagnostic techniques; sensitivity; specificity; agreement; kappa Bovigamtv CSL kit was 88%, 73%, 82% and 0.62; LCx Mycobacterium tuberculosis ASSAY-ABBOTT was 28%, 91%, 46% and 0.13; Mycobacterial Growth Indicator Tube system was 0, 100%, 37% and 0; Ziehl-Neelsen stained method it was 1%, 92%, 47% and -0.6; culture in Lowestein-Jensen was 0, 99%, 51% and -0.12; culture in Stonebrink was 2%, 93%, 51% and -0.5; PCR IS6110 probe in milk samples of 55%, specificity was 96%, agreement was 73% and kappa was 0.49.
Bourne, J.; Donnelly, C.A.; Cox, D.R.; Gettinby, G.; McInerney, J.P.; Morrison, I.; Woodroffe, R. Bovine tuberculosis: towards a future control strategy. Cattle Practice. 2005; 13 (4): 289-294. ISSN: 0969-1251. Note: Reprinted from Veterinary Record. 2003; 167: 207-210.
NAL Call Number: SF961.C37
Descriptors: badgers (Meles meles), cattle, Mycobacterium bovis, pathogenesis, diagnosis, disease prevalence, disease control programs, disease prevention, wildlife as disease reservoirs, disease transmission, UK.
Bourne, J.; Donnelly, C.A.; Cox, D.R.; Gettinby, G.; McInerney, J.P.; Morrison, W.I.; Woodroffe, R. Bovine tuberculosis - towards a science based control strategy. Cattle Practice. 2005; 13 (4): 319-322. ISSN: 0969-1251. Note: Reprinted from Science in Parliament. 2005; 62: 25-28.
NAL Call Number: SF961.C37
Descriptors: cattle, badgers (Meles meles), wild animal disease reservoir, transmission risks, Mycobacterium bovis, animal welfare, control programs; culling, diagnosis, disease control, disease prevalence and prevention, disease surveys, epidemiological surveys, epidemiology, molecular epidemiology, vaccination, vaccines.
Buddle, B.M.; Wedlock, D.N.; Denis, M.; Skinner, M.A. Identification of immune response correlates for protection against bovine tuberculosis. Veterinary Immunology and Immunopathology. 2005 Oct. 18; 108 (1-2): 45-51. ISSN: 0165-2427. Note: Paper presented at the 7th International Veterinary Immunology Symposium Held July 25-30, 2004, Quebec, Canada.
URL: http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number: SF757.2.V38
Descriptors: calves, bovine tuberculosis, disease prevention, immune response, vaccines, Mycobacterium bovis, vaccination, cell mediated immunity, interferons, subcutaneous injection, messenger RNA, gene expression, interleukin 4, tuberculin, disease detection, disease severity, literature reviews.
Buddle, B.M.; Aldwell, F.E.; Skinner, M.A.; Lisle, G.W. de; Denis, M.; Vordermeier, H.M.; Hewinson, R.G.; Wedlock, D.N. Effect of oral vaccination of cattle with lipid-formulated BCG on immune responses and protection against bovine tuberculosis. Vaccine. 2005; 23 (27): 3581-3589.
URL: http://www.sciencedirect.com/science/journal/0264410X
Descriptors: calves, Mycobacterium bovis, Mycobacterium bovis BCG strain vaccine, oral route, 108 colony forming units or 10 pellets of 109 CFU, subcutaneous injections with 106 CFU, varied immune responses, challenge with virulent Mycobacterium bovis, caudal fold tuberculin skin test post vaccination, interferon, interleukin 2, T lymphocytes, lungs, procedure produced significant level of protection compared to non-vaccination.
Cadmus, S.I.B.; Arinola, O.G. Evaluation of the 48 hour, 72 hour and 96 hour readings of tuberculin test for the screening of tuberculosis in cattle. African Journal of Clinica and Experimental Microbiology. 2005; 6 (3): 223-226. ISSN: 1595-689X
URL: http://www.ajol.info/viewarticle.php?jid=47&id=23100&layout=abstract&OJSSID=37fb63efacde72211b5d1fd3c840f425
Descriptors: cattle, Mycobacterium tuberculosis, tuberculin testing, screening, comparison of reading times.
Cadmus, S.I.B.; Atsanda, N.N.; Oni, S.O.; Akang, E.E.U. Bovine tuberculosis in one cattle herd in Ibadan in Nigeria. Veterinarni Medicina. 2004; 49 (11): 406-412. ISSN: 0375-8427
Descriptors: 1 private herd, N'dama and White Fulani (i.e. Bunaji) breeds, bovine tuberculosis survey, introdermal comparative cervical tuberculin test, clinical aspects, diagnosis, diagnostic techniques, disease prevalence, epidemiology, histopathology, molecular epidemiology, Nigeria.
Cai, H.; Tian, X.; Hu, X.D.; Li, S.X.; Yu, D.H.; Zhu, Y.X. Combined DNA vaccines formulated either in DDA or in saline protect cattle from Mycobacterium bovis infection. Vaccine. 2005; 23 (30): 3887-3895. ISSN: 0264-410X
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/30521/description#description
Descriptors: DNA vaccines, Mycobacterium tuberculosis antigens Ag85B, MPT64, MPT83, testing on calves, vaccine plus dimethyldioctyldecyl ammonium bromide (DDA) or saline elicited a strong gamma interferon (IFN-gamma) response, 1 or 2 months post 3rd vaccination, titers, BCG challenge.
Carrique-Mas, J.J.; Medley, G.F.; Green, L.E. Risk of bovine tuberculosis breakdowns in post-foot-and-mouth disease restocked cattle herds in Great Britain. In: Mellor, D.J.; Russell, A.M.; Wood, J.L.N. (Editors). Society for Veterinary Epidemiology and Preventive Medicine Proceedings of a Meeting Held at Nairn, Inverness, Scotland, 30th March 1st April-2005. Published by the Society. 2005: 27-41. ISBN: 0948073691
Descriptors: cattle, bovine tuberculosis, Mycobacterium bovis, disease control, foot and mouth disease virus, FMD, hazards, risk assessment of animal movements, repopulation purchasing risk factors; survival, Great Britain.
Cedeno, I.; de Obaldia, R.; Sanjur, O.; Bayard, V.; Ortega-Barria, E.; Escobar, C. Use of the polymerase chain reaction for diagnosing bovine tuberculosis in Panama. Revue Scientifique et Technique Office International des Epizooties. 2005; 24(3): 1067-1075. ISSN: 0253-1933
NAL Call Number: SF781.R4
Descriptors: cattle industry, Mycobacterium bovis, 60 nasal mucus samples, diagnostic testing, PCR species specific primers for diagnostic program, zoonotic threat to public health, Panama.
Cobos-Marin, L.; Montes-Vargas, J.; Zumarraga, M.; Cataldi, A.; Romano, M.I.; Estrada-Garcia, I.; Gonzalez-y-Merchand, J.A. Spoligotype analysis of Mycobacterium bovis isolates from Northern Mexico. Canadian Journal of Microbiology. 2005 Nov.; 51 (11): 996-1000. Note: In English with a French summaryEnglish. ISSN: 0008-4166
URL: http://pubs.nrc-cnrc.gc.ca/rp-ps/journalDetail.jsp?jcode=cjm&lang=eng
NAL Call Number: 448.8 C162
Descriptors: cattle, Mycobacterium bovis, animal pathogenic bacteria, strains, bovine tuberculosis, genetic techniques and protocols, polymerase chain reaction, loci, repetitive sequences, spoligotyping, spacer oligonucleotide typing, spoligotypes, Mexico.
Collins, J.D. The control of tuberculosis in cattle: an Irish view. Cattle Practice. 2005; 13 (4): 361-367. ISSN: 0969-1251
NAL Call Number: SF961.C37
Descriptors: cattle, badgers (Meles meles), Mycobacterium bovis, Irish Republic.
Cousins, D.V.; Florisson, N. A review of tests available for use in the diagnosis of tuberculosis in non-bovine species. Revue Scientifique et Technique Office International des Epizooties. 2005 December; 24 (3): 1039-1059. ISSN: 0253-1933. Note: In English with summaries in English, French and Spanish.
Descriptors: bovine tuberculosis, negative social and economic impacts, affects domestic and wild animals, animal diversity, zoonotic diseases, intradermal tuberculin test, ELISA, prescribed test for diagnosis in cattle, Mycobacterium bovis, review of various tests used for diagnosis, validated diagnostics for different species, number of animals used for test validation.
Cox, D.R.; Donnelly, C.A.; Bourne, F.J.; Gettinby, G.; McInerney, J.P.; Morrison, W.I.; Woodroffe, R. Simple model for tuberculosis in cattle and badgers. Proceedings of the National Academy of Sciences of the United States of America. 2005 Dec 6; 102 (49): 17588-17593. ISSN: 0027-8424
URL: http://www.pnas.org/
NAL Call Number: 500 N21P
Abstract: As an aid to the study of bovine tuberculosis (TB), a simple model has been developed of an epidemic involving two species, cattle and badgers. Each species may infect the other. The proportion of animals affected is assumed relatively small so that the usual nonlinear aspects of epidemic theory are avoided. The model is used to study the long-run and transient effect on cattle of culling badgers and the effect of a period without routine testing for TB, such as occurred during the 2001 epidemic of foot-and-mouth disease in Great Britain. Finally, by examining the changes in cattle TB over the last 15 years, and with some other working assumptions, it is estimated that the net reproduction number of the epidemic is approximately equal to 1.1. The implications for controlling the disease are discussed.
Descriptors: cattle, bovine tuberculosis, Mycobacterium bovis, disease transmission, epidemiology, badgers (Meles meles), modeling disease transmission, effects of culling badgers, testing interruption, disease control, UK.
Dean, Gillian S.; Rhodes, Shelley G.; Coad, Michael; Whelan, Adam O.; Cockle, Paul J.; Clifford, Derek J.; Hewinson, R. Glyn; Vordermeier, H. Martin. Minimum infective dose of Mycobacterium bovis in cattle. Infection and Immunity. 2005 Oct; 73 (10): 6467-6471. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1.I57
Abstract: The aim of this work was to determine the minimum infective dose of Mycobacterium bovis necessary to stimulate specific immune responses and generate pathology in cattle. Four groups of calves (20 animals) were infected by the intratracheal route with 1,000, 100, 10, or 1 CFU of M. bovis. Specific immune responses (gamma interferon {IFN-[gamma]} and interleukin-4 [IL-4] responses) to mycobacterial antigens were monitored throughout the study, and the responses to the tuberculin skin test were assessed at two times. Rigorous post mortem examinations were performed to determine the presence of pathology, and samples were taken for microbiological and histopathological confirmation of M. bovis infection. One-half of the animals infected with 1 CFU of M. bovis developed pulmonary pathology typical of bovine tuberculosis. No differences in the severity of pathology were observed for the different M. bovis doses. All animals that developed pathology were skin test positive and produced specific IFN-[gamma] and IL-4 responses. No differences in the sizes of the skin test reactions, the times taken to achieve a positive IFN-[gamma] result, or the levels of the IFN-[gamma] and IL-4 responses were observed for the different M. bovis doses, suggesting that diagnostic assays (tuberculin skin test and IFN-[gamma] test) can detect cattle soon after M. bovis infection regardless of the dose. This information should be useful in modeling the dynamics of bovine tuberculosis in cattle and in assessing the risk of transmission.
Descriptors: cattle, Mycobacterium bovis, experimental infection, varying dosages, skin test reactions, diagnostic assays, progress of infection, mathmetical modeling of disease, risk of transmission.
Delahay, R.J.; Cheeseman, C.L; Mallinson, P.J; Rogers, L.M.; Smith, G.C. Badgers and bovine tuberculosis: a review of studies in the ecology of a wildlife disease reservoir. Cattle Practice. 2005; 13(4): 295-299. ISSN: 0969-1251
NAL Call Number: SF961.C37
Descriptors: wild badgers (Meles meles), cattle, wild animals as disease reservoirs, Mycobacterium bovis, UK.
Denis, Michel; Keen, Denise L.; Wedlock, D. Neil; de Lisle, Geoffrey W.; Buddle, Bryce M. Susceptibility of brushtail possums (Trichosurus vulpecula) infected with Mycobacterium bovis is associated with a transient macrophage activation profile. Tuberculosis (Amsterdam). 2005; 85 (4): 235-244. ISSN: 1472-9792
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/638428/description?navopenmenu=-2
Descriptors: Australian brushtail possum (Trichosurus vulpecula), wildlife reservoir for pathogen, Mycobacterium bovis virulent strain, pathogenesis, disease process, experimental infection, aerosol exposure, lung lesions, livers, spleens, blood lymphocytes proliferated, nitric oxide levels in lungs, tumor necrosis factor alpha, transient activation of alveolar macrophages, New Zealand.
Dhakal, M.; Shrestha, R.G.; Jha, V.C.; Dhakal, P.R.; Sato, T.; Morita, Y.; Kozawa, K.; Kimura, H. Heat treatment effects on Mycobacterium spp. isolated from ruminants in Nepal. Veterinary Microbiology. 2005; 106 (3-4): 303-304. ISSN: 0378-1135
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Descriptors: Jersey cow, Murrah buffalo, Mycobacterium avium, Mycobacterium bovis, strains NPMb-2 and NPMb-1, Mycobacterium thermoresistible strains NPMth-2 and NPMth-1, Mycobacterium fortuitum strain NPMfo-1, heat treatment effects, applied and field techniques, single intradermal cervical tuberculin test: SICT, clinical techniques, diagnostic techniques, Nepal.
Dunn, John R.; Kaneene, John B.; Grooms, Daniel L.; Bolin, Steven R.; Bolin, Carole A.; Bruning Fann, Colleen S. Effects of positive results for Mycobacterium avium subsp paratuberculosis as determined by microbial culture of feces or antibody ELISA on results of caudal fold tuberculin test and interferon-gamma assay for tuberculosis in cattle. Journal of the American Veterinary Medical Association. 2005; 226(3): 429-435. ISSN: 0003-1488
URL: http://avmajournals.avma.org/loi/javma
NAL Call Number: 41.8 AM3
Descriptors: cattle, comparison study, positive potential of false positives for Mycobacterium bovis if positive for M. avium ssp paratuberculosis, microbial culture of feces or antibody ELISA, caudal fold tuberculin test or interferon-gamma assay for M. bovis, no significant association was established, 10 herds in Michigan.
Efford, M.; Norbury, G. Ferret population assessment: progress and challenges. In: 13th Australasian Vertebrate Pest Conference, Wellington, New Zealand, 2-6 May 2005. Published by Manaaki Whenua Press, Landcare Research. Lincoln, New Zealand. 2005: 75-80.
Descriptors: cattle, ferrets, Mycobacterium bovis, wild animal disease reservoirs, disease vectors, bait traps; baiting, baits, capture of feral animals, control programs, dispersal of feral animals, invasions, population levels, methodology, pest control, pest management, population density, population dynamics, reservoir hosts, trapping, vertebrate pests, wild animals, New Zealand.
Fend, R.; Geddes, R.; Lesellier, S.; Vordermeier, H.M.; Corner, L.A.L.; Gormley, E.; Costello, E.; Hewinson, R.G.; Marlin, D.J.; Woodman, A.C.; Chambers, M.A. Use of an electronic nose to diagnose Mycobacterium bovis infection in badgers and cattle. Journal of Clinical Microbiology. 2005; 43 (4): 1745-1751. ISSN: 0095-1137
URL: http://jcm.asm.org/cgi/content/abstract/43/4/1745
NAL Call Number: QR46.J6
Abstract: It is estimated that more than 50 million cattle are infected with Mycobacterium bovis worldwide, resulting in severe economic losses. Current diagnosis of tuberculosis (TB) in cattle relies on tuberculin skin testing, and when combined with the slaughter of test-positive animals, it has significantly reduced the incidence of bovine TB. The failure to eradicate bovine TB in Great Britain has been attributed in part to a reservoir of the infection in badgers (Meles meles). Accurate and reliable diagnosis of infection is the cornerstone of TB control. Bacteriological diagnosis has these characteristics, but only with samples collected postmortem. Unlike significant wild animal reservoirs of M. bovis that are considered pests in other countries, such as the brushtail possum (Trichosurus vulpecula) in New Zealand, the badger and its sett are protected under United Kingdom legislation (The Protection of Badgers Act 1992). Therefore, an accurate in vitro test for badgers is needed urgently to determine the extent of the reservoir of infection cheaply and without destroying badgers. For cattle, a rapid on-farm test to complement the existing tests (the skin test and gamma interferon assay) would be highly desirable. To this end, we have investigated the potential of an electronic nose (EN) to diagnose infection of cattle or badgers with M. bovis, using a serum sample. Samples were obtained from both experimentally infected badgers and cattle, as well as naturally infected badgers. Without exception, the EN was able to discriminate infected animals from controls as early as 3 weeks after infection with M. bovis, the earliest time point examined postchallenge. The EN approach described here is a straightforward alternative to conventional methods of TB diagnosis, and it offers considerable potential as a sensitive, rapid, and cost-effective means of diagnosing M. bovis infection in cattle and badgers..
Descriptors: Mycobacterium bovis detection, electronic nose, badgers (Meles meles), cattle, sero testing.
Fischer, E.A.J.; van Roermund, H.J.W.; Hemerik, L.; van Asseldonk, M.A.P.M.; De Jong, M.C.M. Evaluation of surveillance strategies for bovine tuberculosis (Mycobacterium bovis) using an individual based epidemiological model. Preventive Veterinary Medicine. 2005; 67 (4): 283-301. ISSN: 0167-5877
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503315/description#description
NAL Call Number: SF601.P7
Descriptors: bovine tuberculosis status, surveillance system, visual inspection of carcasses at slaughter, ELISA blood sampling post slaughter, gamma-interferon, pre-slaughter of herds and ELISA test on bulk milk, stochastic individual based model simulating a chain of infected herds, epidemiological modeling, possible effects of one infected animal into one herd, analysis of optimization of a 6 approaches, Netherlands.
Fishwick, J. (editor). Cattle practice. Cattle Practice. 2005; 13 (4): 183 pp. ISSN: 0969-1251. Note: Special issue on bovine tuberculosis.
NAL Call Number: SF961.C37
Descriptors: cattle, bovine tuberculosis, Mycobacterium bovis, Mycobacterium bovis BCG strain, Trichosurus vulpecula, Meles meles, diagnosis, diagnostic techniques, disease control programs, disease prevalence, disease transmission, disease vectors and reservoirs, vaccination, wild animals.
Fikru, R.; Bonnet, P.; Moges, W. Prevalence of bovine tuberculosis in indigenous Zebu cattle under extensive farming system in Western Ethiopia. Bulletin of Animal Health and Production in Africa. 2005; 53(1): 85-88. ISSN: 0378-9721. Note: In English with a French summary.
URL: http://www.ajol.info/journal_index.php?ab=bahpa
NAL Call Number: 41.8 B872
Descriptors: indigenous zebu cattle, bovine tuberculosis, Mycobacterium bovis, disease survey, 35 small holder extensive production, housing, feeding, cattle movement patterns, cattle diseases, purpose of cattle keeping, respiratory diseases, trypanosomiasis, black leg, anthrax, diarrhea, etc, intradermal tuberculin tests, modes of disease transmission, Bodji district, Ethiopia.
Foote, M.R.; Nonnecke, B.J.; Waters, W.R.; Palmer, M.V.; Beitz, D.C.; Fowler, M.A.; Miller, B.L.; Johnson, T.E.; Perry, H.B. Effects of increased dietary protein and energy on composition and functional capacities of blood mononuclear cells from vaccinated, neonatal calves. International Journal for Vitamin and Nutrition Research. 2005 Sept.; 75 (5): 357-368. ISSN: 0300-9831
URL: http://www.verlag-hanshuber.com/zeitschriften/journal.php?abbrev=VIT
NAL Call Number: 389.8 Z33
Abstract: Effects of increased protein and energy provided by an intensified milk replacer on the antigen-specific, cell-mediated immune response of the neonatal calf were examined. Calves were fed a standard (0.45 kg/day of a 20% crude protein, 20% fat milk replacer; n = 11) or intensified (1.14 kg/day of a 28% crude protein, 20% fat milk replacer; n = 11) diet from 0 to 6 weeks of age. All calves were vaccinated with Mycobacterium bovis bacillus Calmette-Guerin (BCG) at 1 week of age. The daily weight gain of intensified-diet calves (0.62 kg/day) was greater than the weight gain of standard-diet calves (0.29 kg/day). Liver, kidney, heart, thymus, and subcervical lymph nodes from intensified-diet calves were heavier than the same organs from standard-diet calves. Flow cytometric analysis of peripheral blood mononuclear cell (PBMC) populations indicated that CD4+ cells, gamma delta TCR+ cells, and monocyte percentages, although unaffected by diet during the first 5 weeks of the study, were higher in intensified-diet calves at week 6. The decline in gamma delta d TCR+ cell percentages and increase in B cell percentages with increasing age seen in all calves are characteristic of the maturing immune system of the calf. CD8+ T cell or B cell percentages were not affected by diet. In intensified-diet calves, percentages of CD4+ expressing interleukin-2 receptor increased and percentages of gamma delta TCR+ cells expressing interleukin-2 receptor decreased with time. The same populations in standard-diet calves did not change with time. Percentages of CD4+ and CD8+ T cells, and B cells expressing MHC class II antigen, were unaffected by diet or age. Although mitogen-induced interferon (IFN)-gamma and nitric oxide (NO) secretion increased with age for all calves, PBMC from intensified-diet calves produced less IFN-gamma and more NO than did cells from standard-diet calves at week 6 of the study. Antigen-induced secretion of IFN-gamma and NO also increased with age but was unaffected by diet. Antigen-elicited delayed-type hypersensitivity was unaffected by diet, suggesting increased dietary protein and energy did not alter adaptive immunity in vivo. Overall, these results suggest that feeding calves a commercially available, intensified milk replacer affects minimally the composition and functional capacities of PBMC populations. Additional research is necessary to determine whether these subtle effects influence the calf's susceptibility to infectious disease.
Descriptors: calves, neonates, calf feeding, dietary protein, dietary energy sources, monocytes, vaccination, milk replacer, immune response, cell mediated immunity, crude protein, CD8+ T lymphocytes, Mycobacterium bovis BCG, BCG vaccine, bovine tuberculosis, liveweight gain, animal organs, tissue weight, CD4+T lymphocytes, B lymphocytes, interleukin 2, major histocompatibility complex, histocompatibility antigens, interferons.
Gallagher, J. Tuberculosis: tracing the dilemma. Veterinary Times. 2005; 35 (27): 14-17. ISSN: 1352-9374
Descriptors: badgers (Meles meles) as pathogenic disease reservoirs, cattle, Mycobacterium bovis, epidemiology, disease prevalence and transmission, seasonal effects, disease control strategies, trapping, pathobiology, absesses, various organs with lesions, latent infections, vaccines, bites, wounds, mortality rates, England.
Gilbert, M.; Mitchell, A.; Bourn, D.; Mawdsley, J.; Clifton-Hadley, R.; Wint, W. Cattle movements and bovine tuberculosis in Great Britain. Nature. 2005; 435 (7041): 491-496. ISSN: 0028-0836
URL: http://www.nature.com/index.html
NAL Call Number: 472 N21
Abstract: For 20 years, bovine tuberculosis (BTB) has been spreading in Great Britain (England, Wales and Scotland) and is now endemic in the southwest and parts of central England and in southwest Wales, and occurs sporadically elsewhere. Although its transmission pathways remain poorly understood, the disease's distribution was previously modelled statistically by using environmental variables and measures of their seasonality. Movements of infected animals have long been considered a critical factor in the spread of livestock diseases, as reflected in strict import/export regulations, the extensive movement restrictions imposed during the 2001 foot-and-mouth disease outbreak, the tracing procedures after a new case of BTB has been confirmed and the Government's recently published strategic framework for the sustainable control on BTB. Since January 2001 it has been mandatory for stock-keepers in Great Britain to notify the British Cattle Movement Service of all cattle births, movements and deaths. Here we show that movements as recorded in the Cattle Tracing System data archive, and particularly those from areas where BTB is reported, consistently outperform environmental, topographic and other anthropogenic variables as the main predictor of disease occurrence. Simulation distribution models for 2002 and 2003, incorporating all predictor categories, are presented and used to project distributions for 2004 and 2005.
Descriptors: cattle, bovine tuberculosis, Mycobacterium bovis, animal transport, geographical distribution, disease transmission tracking, epidemiology, simulation models, Great Britain.
Green, L.E.; Cornell, S.J. Investigations of cattle herd breakdowns with bovine tuberculosis in four counties of England and Wales using VETNET data. Preventive Veterinary Medicine. 2005 Sept 12; 70 (3-4): 293-311. ISSN: 0167-5877
NAL Call Number: SF601.P7
Abstract: Cattle herd breakdown (HBR) with bovine tuberculosis (BTB) was investigated for farms in four counties of England and Wales outside southwest England from 1986 to early 2000. Data from the national database of TB testing history (VETNET) were used. Factors that influenced HBR included calendar time, herd size, number of cattle tested, the test type, the inter-test interval and spatial grouping of farms. Herd tests other than routine herd tests had an increased risk of HBR in all four counties. In all counties, the risk of HBR increased with calendar time and in Shropshire a test interval of 3 years was associated with an increased risk of HBR compared with a 1-year test interval. In Staffordshire and Sussex, a 4-year test interval was associated with a lower risk of HBR compared with a 1-year test interval. There was no evidence of spatial clustering of HBR in West Glamorgan (equal spatial risk in a 15-30 km radius) and weak evidence of spatial clustering in Shropshire (7-15 km) and Sussex (5-10 km). In Staffordshire, there was evidence of spatial (2-4 km) and time (3-4 years) clustering of HBR. The locally increased rate of testing following a confirmed HBR increased the detection of infected herds but did not prevent local spread in two of the four counties (Shropshire and Staffordshire) since the rate of HBR increased linearly from 1988 to 2000. The main conclusion is that there were both local and distant components of spread.
Descriptors: dairy cattle, Mycobacterium bovis, bovine tuberculosis, disease prevalence, disease transmission, herd size, risk assessment, risk factors, herd health, databases, herd breakdown, VETNET database, England, Wales.
Green, L. Modelling disease - a guide for the cattle practitioner. Cattle Practice. 2005; 13 (3): 243-248. ISSN: 0969-1251
NAL Call Number: SF961.C37
Descriptors: cattle, cattle diseases, Mycobacterium bovis, foot and mouth disease, disease models, mathematical models, statistical models, analysis, risk assessment, infectious disease processes, disease transmission hypotheses.
Griffin, J.M.; Williams, D.H.; Kelly, G.E.; Clegg, T.A.; O' Boyle, I.; Collins, J.D.; More, S.J. The impact of badger removal on the control of tuberculosis in cattle herds in Ireland. Preventive Veterinary Medicine, 2004; 67: 237-266. ISSN: 0167-5877
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503315/description#description
NAL Call Number: SF601.P7
Descriptors: badgers (Meles meles), cattle, Mycobacterium bovis, diagnosis, disease prevention and control programs, disease-prevalence, wild life as disease reservoirs, epidemiology, regression analysis, trapping, vector control, wild animals, Irish Republic.
Griffin, J.M.; More, S.J.; Clegg, T.A.; Collins, J.D.; O'Boyle, I.; Williams, D.H.; Kelly, G.E.; Costello, E.; Sleeman, D.P.; O' Shea, F.; Duggan, M.; Murphy, J.; Lavin, D.P.T. Tuberculosis in cattle: the results of the four-area project. Irish Veterinary Journal. 2005; 58 (11): 629-636. ISSN: 0368-0762.
URL: www.veterinary-ireland.org
NAL Call Number: 41.8 IR4
Descriptors: Mycobacterium bovis, outbreaks, cattle, badgers (Meles meles), epidemiology, disease control and prevention, disease prevalence, disease transmission, wild badgers as a disease pathogen reservoir, reviews, Irish Republic.
Griffin, J.M.; Clegg, T.A.; Kelly, G.E.; Williams, D.H.; O'Boyle, I.; Collins, J.D.; More, S.J. The impact of badger removal on the control of tuberculosis in cattle herds in Ireland. In: D.J. Mellor; A.M. Russell; J.L.N. Wood (Editors). Society for Veterinary Epidemiology and Preventive Medicine Proceedings of a Meeting Held at Nairn, Inverness, Scotland, 30th March 1st April 2005. Published by Society for Veterinary Epidemiology and Preventive Medicine. Roslin, UK. 2005; 42-54. ISBN: 0948073691
Descriptors: cattle, badgers (Meles meles), Mycobacterium bovis, disease control, disease vectors, risk assessment, survival, tuberculosis, Ireland.
Hewes, C.A.; Schneider, R.K.; Baszler, T.V.; Oaks, J.L. Septic arthritis and granulomatous synovitis caused by infection with Mycobacterium avium complex in a horse. Journal of the American Veterinary Medical Association. 2005 June 15; 226 (12): 2035-2038. ISSN: 0003-1488
NAL Call Number: 41.8 Am3
Descriptors: horses, arthritis, sepsis (infection), horse diseases, synovitis, Mycobacterium avium complex, mycobacterial diseases, lameness, case studies, pain, granulomatous-synovitis
Hope, J.C.; Thom, M.L.; Villareal-Ramos, B; Vordermeier, H.M.; Hewinson, R G; Howard, C J. Exposure to Mycobacterium avium induces low-level protection from Mycobacterium bovis infection but compromises diagnosis of disease in cattle (vol 141, pg 432, 2005). Clinical and Experimental Immunology. 2005; 142 (3): 595. ISSN: 0009-9104. Note: Errata: article.
URL: http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number: QR180.C5
Descriptors: Mycobacterium bovis, effects of exposure to Mycobacterium avium, skin testing, cattle testing and diagnosis unreliable.
Hope, J.C.; Thom, M.L.; Villarreal-Ramos, B.; Vordermeier, H.M.; Hewinson, R.G.; Howard, C.J. Exposure to Mycobacterium avium induces low-level protection from Mycobacterium bovis infection but compromises diagnosis of disease in cattle. Clinical and Experimental Immunology. 2005; 141 (3): 432-439. ISSN: 0009-9104
URL: http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number: QR180.C5
Descriptors: calves, Mycobacterium avium exposure, Mycobacterium bovis challenge, immune responses, exposure to Mycobacterium avium may mask diagnosis of Mycobacterium bovis infection even with specific antigens can contribute to disease transmission in the field.
Hope, J.C.; Thom, M.L.; Villarreal-Ramos, B.; Vordermeier, H.M.; Hewinson, R.G.; Howard, C.J. Exposure to Mycobacterium avium induces low-level protection from Mycobacterium bovis infection but compromises diagnosis of disease in cattle. Clinical and Experimental Immunology. 2005; 141 (3): 432-439. ISSN: 0009-9104
URL: http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number: QR180.C5
Descriptors: calves, cattle diseases, Mycobacterium avium, Mycobacterium bovis, bacterial antigens, diagnosis, diagnostic techniques, experimental infections, development of immune response, immunity, interferon, T lymphocytes, pathogenesis, postmortem examinations, skin tests, tuberculin.
Hope, J.C.; Thom, M.L.; Villarreal-Ramos, B.; Vordermeier, H.M.; Hewinson, R.G.; Howard, C.J. Vaccination of neonatal calves with Mycobacterium bovis BCG induced protection against intranasal challenge with virulent M. bovis (vol 139, pg 48, 2005). Clinical and Experimental Immunology. 2005; 140 (1): 192. ISSN: 0009-9104. Note: Errata; Article.
URL: http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number: QR180.C5
Descriptors: neonatal calves, vaccination with Mycobacterium bovis, BCG, level of protection with trans-nasal challenge with virulent Mycobacterium bovis.
Hope, J.C.; Thom, M.L.; Villarreal-Ramos, B.; Vordermeier, H.M.; Hewinson, R.G.; Howard, C.J. Vaccination of neonatal calves with Mycobacterium bovis BCG induces protection against intranasal challenge with virulent M. bovis. Clinical and Experimental Immunology. 2005; 139 (1): 48-56. ISSN: 0009-9104
URL: http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number: QR180.C5
Descriptors: 2 week old calves, neonates vaccinated with Mycobacterium bovis BCG, Mycobacterium bovis, virulent strain challenge intra-nasally, experimental infection, tissue examined for lesions, chest lymph nodes, neonate vaccination induced significant protection against disease, potential for disease control.
Jahans, K.L.; Worth, D.; Brown, J.; Monies, R.J. Detection of bovine tuberculosis in spill-over hosts. Research in Veterinary Science. 2005; 78 (Suppl. A): 23-24. ISSN: 0034-5288. Note: Meeting abstract. 59th Annual Conference of the Association for Veterinary Teaching and Research Work, Scarborough, England; March 21 -23, 2005
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/623070/description#description
NAL Call Number: 41.8 R312
Descriptors: Mycobacterium bovis, cattle, buffalo, bison, sheep, goats, dogs, deer, cats, badgers, pigs, domestic and wildlife species, spill over hosts, end hosts, animal pathogen reservoirs, maintenance hosts.
Jesenska, Andrea; Pavlova, Martina; Strouhal, Michal; Chaloupkova, Radka; Tesinska, Iva; Monincova, Marta; Prokop,-Zbynek; Bartos, Milan; Pavlik, Ivo; Rychlik, Ivan; Moebius, Petra; Nagata, Yuji; Damborsky, Jiri. Cloning, biochemical properties, and distribution of mycobacterial haloalkane dehalogenases. Applied and Environmental Microbiology. 2005; 71 (11): 6736-6745. ISSN: 0099-2240
URL: http://www.pubmedcentral.nih.gov/tocrender.fcgi?action=archive&journal=83
NAL Call Number: 448.3 Ap5
Descriptors: Mycobacterium bovis, Mycobacterium tuberculosis, haloalkane dehalogenases, enzymes, cloning of enzyme genes dmbA and dmbB of M. bovis 5033/66, dehalogenase activity of translation products, distribution of genes in following species--Mycobacterium bovis, Mycobacterium bovis BCG, Mycobacterium africanum, Mycobacterium caprae, Mycobacterium microti, and Mycobacterium pinnipedii, characterization of proteins, evolution and distribution of haloalkane dehalogenases among mycobacteria.
Jiang, XiuYun; He, ZhaoYang. DNA injection via in vivo electroporation: a new immunisation technique for bovine tuberculosis. Chinese Journal of Zoonoses. 2005; 21 (2): 182-184. ISSN: 1002-2694. Note: In Chinese.
Descriptors: cattle, pigs, sheep, Mycobacterium bovis, DNA injection technique, immune reactions, vaccines, electroporation, immunization, 2 different vaccines used with no interference between them.
Kumar, K.; Swamy, M. Miliary tuberculosis in cross-bred cows. Indian Journal of Veterinary Pathology. 2005; 29 (1): 50-51. ISSN: 0250-4758
Descriptors: cattle, tuberculosis, Mycobacterium tuberculosis, India.
Lutze Wallace, C.; Turcotte, C.; Sabourin, M.; Berlie-Surujballi, G.; Barbeau, Y.; Watchorn, D.; Bell, J. Spoligotyping of Mycobacterium bovis isolates found in Manitoba. Canadian Journal of Veterinary Research = Revue Canadienne de Recherche Veterinaire. 2005 Apr; 69 (2): 143-145. ISSN: 0830-9000. Note: In English with a French summary.
URL: http://www.pubmedcentral.nih.gov/tocrender.fcgi?action=archive&journal=133
NAL Call Number: SF601.C24
Descriptors: deer, cattle, elk, Cervus elaphus Canadensis, Mycobacterium bovis, microsatellite repeats, 44 isolates, tissue sources, hybridized with oligonucleotide 12 (MB-1 type), oligonucleotide 12 (MB-1 type), oligonucleotide 12 (MB-2 type), Manitoba, Canada.
Lutze-Wallace, C.; Turcotte, C. Laboratory diagnosis of bovine tuberculosis in Canada for calendar year 2004. Canadian Veterinary Journal. 2005; 46 7(9): 797-799. ISSN: 0008-5286. Note: In English and French.
URL: http://www.pubmedcentral.nih.gov/tocrender.fcgi?action=archive&journal=202
NAL Call Number: 41.8 R3224
Descriptors: wild animals, zoo animals, livestock, bison, cattle, Cervus elaphus, deer, elephants, equines, cats, bacterial disease, Mycobacterium, Mycobacterium avium, Mycobacterium avium ssp paratuberculosis, Mycobacterium bovis, Mycobacterium fortuitum, Mycobacterium kansasii, Mycobacterium flavescens, Mycobacterium triviale, Mycobacterium terrae, red deer, pigs, Suiformes, disease diagnosis, disease surveys, Alberta, British Columbia, Manitoba, Ontario, Quebec, Saskatchewan, Canada.
Mahendra-Pal Importance of zoonoses in public health. Indian Journal of Animal Sciences. 2005; 75 (5): 586-591. ISSN: 0367-8318
NAL Call Number: 41.8 IN22
Descriptors: cattle, humans, wild animals, Mycobacterium bovis, Yersinia pestis, zoonotic diseases, animal diseases, disease prevalence, control programs, disease prevention, epidemiology, human diseases, morbidity, mortality, plague, public health, sanitation, hygiene, zoonoses, Gujarat, Maharashtra, India, USA.
Maheshwari, Arpan; Verma, Rishendra. Evaluation of three antigens by enzyme-linked immunosorbent assay (ELISA) for the detection of Mycobacterium bovis infection in Indian cattle for field use. Indian Journal of Animal Sciences. 2005; 75 (4): 401-406. ISSN: 0367-8318
NAL Call Number: 41.8 IN22
Descriptors: Mycobacterium bovis AN5, crude antigens form purified protein derivative PPD, species specific phenolic glycolipid, 3 groups of cattle, cattle testing with tuberculin, not tuberculin tested, tuberculin testing in last 14 days, sera collected, ELISA assay, histogram cut off values ELISA assay with PPD, sensitivity and specificity of assay depends on population tested.
Manal, S.H.; Hamid, M.E.; El Jalii, I.M.; Ali, A.S. Correlation between microscopic examination and culture for detection and differentiation of mycobacterial isolates from cattle in the Sudan. Pakistan Journal of Biological Sciences. 2005; 8 (2): 284-286.
URL:http://ansijournals.com/3/detail.php?id=1&jid=pjbs&theme=3&issueno=106&articleno=5356
Descriptors: cattle, postmortem sampling, slaughtered animals, lymph nodes, tuberculous lungs, histopathology, microscopic examination Zeilh-Neelsen stain, culture on Lowenstein-Jensen (L-J) medium, detection and differentiation of mycobacterium species isolates, Mycobacterium farcinogenes, Mycobacterium bovis, differential detection, Khartoum State, Sudan.
Maue, Alexander C.; Waters, W. Ray; Davis, William C.; Palmer, Mitchell V.; Minion, F. Chris; Estes, D. Mar. Analysis of immune responses directed toward a recombinant early secretory antigenic target six-kilodalton protein-culture filtrate protein 10 fusion protein in Mycobacterium bovis infected cattle. Infection and Immunity. 2005 Oct; 73 (10): 6659-6667. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1.I57
Abstract: Cell-mediated immune responses are critical for protective immunity to mycobacterial infections. Recent progress in defining mycobacterial antigens has determined that region of difference 1 (RD1) gene products induce strong T-cell responses, particularly the early secretory antigenic target 6-kDa (ESAT-6) protein and culture filtrate protein 10 (CFP10). However, comprehensive analysis of the immune response towards these antigens is incompletely characterized. To evaluate recall responses to ESAT-6 and CFP10, peripheral blood mononuclear cells from M. bovis-infected cattle were stimulated in vitro with a recombinant ESAT-6 (rESAT-6)-CFP10 fusion protein and compared to responses induced by M. bovis-derived purified protein derivative. Following antigenic stimulation, activation marker expression was evaluated. Significant proliferative responses (P < 0.05) were evident in CD4+, CD8+, immunoglobulin M-positive, and CD172a+ cell fractions after 6 days of culture. Expression of CD25 and CD26 was increased (P < 0.05) on CD4+, CD8+, and [gamma][delta] T-cell-receptor-positive cells. CD4+ and CD8+ cells also exhibited significant changes (P < 0.05) in expression of CD45 isoforms. Using a flow cytometry-based proliferation assay, it was determined that CD45R expression is downregulated (P < 0.05) and that CD45RO expression is upregulated (P < 0.05) on proliferating (i.e., activated) CD4+ cells. Collectively, data indicate that recall immune responses directed toward the rESAT-6-CFP10 fusion protein or purified protein derivative are comparable and that recall to mycobacterial antigens correlates with a CD45RO+ phenotype.
Descriptors: cattle, cell-mediated responses, mycobacterian antigens, 1 (RD1) gene products, T cell responses, 6kDa (ESAT 6) protein and culture filtrate protein 10 (CFP10), animal experiment.
McCorry, T.; Whelan, A.O.; Welsh, M.D.; McNair, J.; Walton, E.; Bryson, D.G.; Hewinson, R.G.; Vordermeier, H.M.; Pollock, J.M. Shedding of Mycobacterium bovis in the nasal mucus of cattle infected experimentally with tuberculosis by the intranasal and intratracheal routes. Veterinary Record. 2005 Nov. 12; 157 (20) 613-618. ISSN: 0042-4900
URL: http://veterinaryrecord.bvapublications.com/
NAL Call Number: 41.8 V641
Descriptors: cattle, Mycobacterium bovis, disease transmission, experimental infection, routes of infection, pathogen shedding, nasal mucus.
Mdegela, R.H.; Karimuribo, E.; Kusiluka, L.J.M.; Kabula, B.; Manjurano, A.; Kapaga, A.M.; Kambarage, D.M. Mastitis in smallholder dairy and pastoral cattle herds in the urban and peri-urban areas of the Dodoma municipality in Central Tanzania. Livestock Research for Rural Development. 2005; 17 (11): 123. ISSN: 0121-3784
URL: http://www.cipav.org.co/lrrd/lrrd17/11/mdeg17123.htm
Descriptors: 64 small holder dairy cattle, disease levels, ELISA, single comparative intradermal tuberculin tests, Arcanobacterium pyogenes, Aspergillus, Bacillus, Brucella, Escherichia coli, Klebsiella, Mucor, Mycobacterium sp, Mycobacterium avium complex, Mycobacterium fortuitum, Mycobacterium phlei, Mycobacterium smegmatis, Serratia, Staphylococcus, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus intermedius, Hyphomycetes, Mucoraceae, Mycobacterium flavescens, Mycobacterium gordonae, Dodoma, Tanzania.
Mellor, D.J.; Russell, A.M.; Wood, J.L.N. (Editors). Society for Veterinary Epidemiology and Preventive Medicine. Proceedings of a Meeting Held at Nairn, Inverness, Scotland, 30th March-1st April 2005. Published by the Society. 2005. 277 pp. ISBN: 0948073691.
Descriptors: many papers, topics include animals diseases, epidemiology, disease prevalence, disease transmission and spread, disease control and prevention, diagnosis, reservoir hosts, public health aspects, bovine tuberculosis, Mycobacterium bovis, classical swine fever, rabies, pancreatic necrosis virus, foot and mouth disease, avian influenza A virus, Streptococcus suis, Escherichia coli, Campylobacter, Salmonella spp., Ostertagia ostertagi, broilers, domestic livestock, wild animal disease carriers, UK.
Menzies, F.D.; Neill, S.D. Bovine tuberculosis: controlling cattle-to-cattle transmission. Cattle Practice. 2005; 13 (4): 441-446. ISSN: 0969-1251
NAL Call Number: SF961.C37
Descriptors: cattle, Mycobacterium bovis, transmission between cattle, controlling disease spread.
Monaghan, M.L.; Doherty, M L.; Collins, J.D.; Kazda, J.F.; Quinn, P.J. The tuberculin test. Cattle Practice. 2005; 13 (4): 337-345. ISSN: 0969-1251
NAL Call Number: SF961.C37
Descriptors: cattle, Mycobacterium bovis, tuberculin skin testing, efficacy, UK.
Morales, A.; Martinez, I.; Carlos, A.; Alvarez, G.; Alvarez, M.; Maldonado, J. Comparacion de histopatologia, cultivo y PCR en el diagnostico de tuberculosis bovina. [Comparison of histopathology, culture and PCR in the diagnosis of bovine tuberculosis.] Revista Cientifica, Facultad de Ciencias Veterinarias, Universidad del Zulia. 2005; 15 (2): 103-108. ISSN: 0798-2259. Note: In Spanish with an English summary.
Descriptors: cattle, Mycobacterium bovis, bovine tuberculosis, tuberculin testing, diagnosis, diagnostic techniques, histopathology, PCR of tissue, histopathological analysis, bacterial isolation, Mexico.
More, S.J. Towards eradication of bovine tuberculosis in Ireland: a critical review of progress. Cattle Practice. 2005; 13 (4): 313-318. ISSN: 0969-1251
NAL Call Number: SF961.C37
Descriptors: cattle diseases, Mycobacterium bovis, tuberculosis control program, disease transmission from wildlife to cattle, wildlife disease reservoir, cattle to cattle transmission, epidemiology, development of a vaccine for badgers (Meles meles), eradication strategy, Irish Republic.
More, S.J. Towards eradication of bovine tuberculosis in Ireland: a critical review of progress. In: D.J. Mellor; A.M. Russell; J.L.N. Wood. (Editors). Society for Veterinary Epidemiology and Preventive Medicine Proceedings of a Meeting Held at Nairn, Inverness, Scotland, 30th March-1st April, 2005. Published by the Society. 2005; 13-23. ISBN: 0948073691
Descriptors: Mycobacterium bovis, bovine tuberculosis, eradication program, evidence of disease transmission badgers to cattle, wildlife reservoirs difficult to control, program for effective vaccine for badgers, Ireland.
Morrison, W.I.; Bourne, F.J.; Cox, D.R.; Donnelly, C.A.; Gettinby, G.; McInerney, J.P.; Woodroffe, R. Pathogenesis and diagnosis of infections with Mycobacterium bovis in cattle. Cattle Practice. 2005; 13 (4): 351-360. ISSN: 0969-1251
NAL Call Number: SF961.C37
Descriptors: cattle, Mycobacterium bovis, disease development, pathogenesis, diagnostic approaches, UK.
Neill, S.D.; Skuce, R.A.; Pollock, J.M. Tuberculosis - new light from an old window. Journal of Applied Microbiology. 2005; 98 (6): 1261-1269. ISSN: 1364-5072
URL: http://www3.interscience.wiley.com/journal/118490255/home
NAL Call Number: QR1.J687
Descriptors: bovine tuberculosis, zoonotic aspects, new information about Mycobacterium bovis, recent developments, pathogenesis, epidemiology, disease eradication, diagnosis, vaccination.
Nonnecke, B.J.; Waters, W.R.; Foote, M.R.; Palmer, M.V.; Miller, B.L.; Johnson, T.E.; Perry, H.B.; Fowler, M.A. Development of an adult-like cell-mediated immune response in calves after early vaccination with Mycobacterium bovis bacillus Calmette-Guerin. Journal of Dairy Science. 2005 Jan.;88(1): 195-210. ISSN: 0022-0302
URL: http://jds.fass.org/contents-by-date.0.shtml
NAL Call Number: 44.8 J822
Descriptors: Mycobacterium bovis BCG, lymphocyte proliferation, T lymphocytes.
Nonnecke, B.J.; Waters, W.R.; Foote, M.R.; Palmer, M.V.; Miller, B.L.; Johnson, T.E.; Perry, H.B.; Fowler, M.A. Development of an adult-like cell-mediated immune response in calves after early vaccination with Mycobacterium bovis bacillus Calmette-Guerin. Journal of Dairy Science. 2005; 88 (1): 195-210. ISSN: 0022-0302
URL: http://jds.fass.org/contents-by-date.0.shtml
NAL Call Number: 44.8 J822
Descriptors: Holstein bull calves, effects of neonatal vaccination, young adults, attenuated strain of Mycobacterium bovis BCG, effects on antigen-specific cellular and humoral immune responses, ontogeny of adaptive immune response, functional capacities of blood mononuclear cell populations, 1-12 week time periods, nulliparous heifers vaccinated, effects of animal maturity on response, bovine neonate can mount a vigorous, adult like cell mediated immune response after early age vaccination.
Norby, B.; Bartlett, P.C.; Grooms, D.L.; Kaneene, J.B.; Bruning-Fann, C.S. Use of simulation modeling to estimate herd-level sensitivity, specificity, and predictive values of diagnostic tests for detection of tuberculosis in cattle. American Journal of Veterinary Research. 2005; 66 (7): 1285-1291
Descriptors: cattle herds, Mycobacterium bovis, diagnosis, diagnostic techniques, estimation, computer simulation models for testing scenarios for tuberculosis, Michigan, US.
O'Rourke, K. Teasing out Mycobacterium bovis' role in the tuberculosis crisis. Journal of the American Veterinary Medical Association. 2005; 227 (6): 871. ISSN: 0003-1488
URL: http://avmajournals.avma.org/loi/javma
NAL Call Number: 41.8 AM3
Descriptors: cattle, humans, meat, meat products, milk, food contamination, Mycobacterium bovis, epidemiology, disease distribution, disease prevalence, disease transmission, zoonoses.
Oakey, J.; Forbes-Faulkner, J.; Gilpin, C.; Murdoch, B.; Johnson, S. Pyogranuloma caused by Mycobacterium asiaticum infection in a steer. Journal of Veterinary Diagnostic Investigation. 2005 July; 17 (4): 378-382. ISSN: 1040-6387
NAL Call Number: SF774.J68
Abstract: In 2003, a steer carcass was condemned at a Central Queensland abattoir because of metastatic tumors. In addition, a granulomatous lesion was found in the mediastinal lymph node. Histological examination showed this to be a pyogranuloma, typically associated with Rhodococcus or the Nocardia/Streptomyces group. However, in this case, the only etiological agent was an acid-fast bacillus, which would normally be associated with a more fibrous lesion. A number of nucleic acid-based techniques were used, and the isolate was identified as Mycobacterium asiaticum. This organism is a rarely encountered opportunistic pathogen of humans, associated with subtropical climates. This is the first report of this organism causing infection in cattle. The similarities between this case and cases of human disease are discussed.
Descriptors: cattle, steer, Mycobacterium asiaticum, granulomatous lesions, mycobacterial diseases, case study, neoplasms, inflammation, pathogenesis, disease diagnosis, pyogranuloma, Australia.
Olea-Popelka, F.J.; Flynn, O.; Costello, E.; McGrath, G.; Collins, J.D.; O'Keeffe, J.; Kelton, D.F.; Berke, O.; Martin, S.W. Spatial relationship between strains in cattle and badgers in four areas in Ireland. Preventive Veterinary Medicine. 2005; 71 (1-2): 57-70. ISSN: 0167-5877
URL:http://www.elsevier.com/wps/find/journaldescription.cws_home/503315/description#description
NAL Call Number: SF601.P7
Descriptors: Mycobacterium bovis strains, cattle, Meles meles, badgers setts, centroid of a cattle farm, logistic model, spatial clusters of strains, can be both in cattle and badgers, wild animals as reservoirs, dynamics of badger movements, epidemiology, transmission of bacteria from badgers to cattle, 4 areas of Ireland.
Olea-Popelka, F.J.; Phelan, J.; White, P.W.; McGrath, G.; Collins, J.D.; O' Keeffe, J.; Duggan, M.; Collins, D.M.; Kelton, D.F.; Berke, O; More, S.J.; Martin, S.W. Quantifying badger exposure and the risk of bovine tuberculosis for cattle herds in county Kilkenny, Ireland. Preventive Veterinary Medicine. 2006; 75 (1/2): 34-46.
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503315/description#description
NAL Call Number: SF601.P7
Descriptors: badgers (Meles meles), quantifying badger exposure, cattle, bovine tuberculosis risk, Ireland.
Oru C, E. Meningoencephalitis tuberculosa in a Holstein Cow. Veterinary Pathology. 2005 Nov; 42 (6): 856-858. ISSN: 0300-9858
NAL Call Number: 41.8 P27
Abstract: The gross and histopathologic lesions of meningoencephalitis tuberculosa in a 4-year-old Holstein cow showing clinical signs compatible with bovine spongiform encephalopathy are described in this report. Grossly, numerous gray to yellow, firm and caseous nodules were seen on the ventral surfaces of the brain and in the lateral and fourth ventricles. Histopathologically, foci of caseation and dystrophic mineralization were surrounded by multinucleated giant cells, epitheloid macrophages, plasma cells, lymphocytes and fibrous proliferation. Ziehl-Neelsen stains of the lesions revealed masses of slender acid-fast bacilli in the necrotic centers of lesions and within surrounding giant cells.
Descriptors: dairy cows, brain infection, histopathology, bovine tuberculosis, Mycobacterium, disease diagnosis, case study.
Palmer, Mitchell V.; Waters, W. Ray; Thacker, Tyler C.; Stoffregen, William C.; Thomsen, Bruce V.; Slaughter, Ralph E.; Jones, Stephen L.; Pitzer, Josh E.; Minion, F. Chris. Experimental infection of reindeer (Rangifer tarandus) with Mycobacterium bovis: pathological & immunological findings. Proceedings. Annual Meeting of the United States Animal Health Association. 2005; 108: 113-116. ISSN: 0082-8750
URL: http://www.usaha.org/meetings/
NAL Call Number: 49.9 UN3R
Descriptors: reindeer (Rangifer tarandus), Mycobacterium bovis, bovine tuberculosis, experimental infection, disease pathology, disease process, immunological responses, diagnostic techniques.
Parra, A.; Larrasa, J.; Garcia, A.; Alonso, J.M.; Hermoso de Mendoza, J. Molecular epidemiology of bovine tuberculosis in wild animals in Spain: A first approach to risk factor analysis. Veterinary Microbiology. 2005 Oct. 31; 110 (3-4): 293-300. ISSN: 0378-1135
URL:http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Descriptors: Mycobacterium bovis, animal pathogenic bacteria, risk factors, epidemiology, bovine tuberculosis, wild animals, ungulates, genetic markers, hosts, loci, symptoms, seasonal variation, disease prevalence, molecular epidemiology, reproductive season, hunting season, Spain.
Pavlik, I.; Trcka, I.; Parmova, I.; Svobodova, J.; Melicharek, I.; Nagy, G.; Cvetnic, Z.; Ocepek, M.; Pate, M.; Lipiec, M. Detection of bovine and human tuberculosis in cattle and other animals in six Central European countries during the years 2000-2004. Veterinarni Medicina. 2005; 50 (7): 291-299. ISSN: 0375-8427
Descriptors: cattle, zoo animals, Bactrian camels (Camelus ferus) in Czech Repuglic, a Siberian tiger (Panthera tigris f. altaica) in Hungary, a bison (Bison bison), an eland (Taurotragus oryx) in Poland, a dromedary camel (Camelus dromedarius), two bison in Slovenia, in wild animals, wild boar, wild red deer, European bison, roe deer, skin testing, disease status, Mycobacterium bovis, 6 Central European countries, Croatia, the Czech Republic, Hungary, Poland, Slovakia, and Slovenia.
Pavlik, I.; Jahn, P.; Chvatal, O.; Kalova, L.; Matlova, L.; Dvorska, L.; Treml, F.; Nesnalova, E.; Novotny, L.; Halouzka, R. Plicni tuberkuloza u kone zpusobena puvodcem aviarni tuberkulozy. [Pulmonary tuberculosis in a horse caused by the causal agent of avian tuberculosis.] Veterinarstvi. 2005; 55 (3): 140-145. ISSN: 0506-8231. Note: In Czech with an English summary. ISSN: 0506-8231
Descriptors: horses, 16 year old mare, interstitial pneumonia, lung infection, case study, Mycobacterium avium, Mycobacterium avium ssp. avium serotype 2 and genotypes dnaJ+, IS901+ and IS1245+isolates, Commission Decision No. 2004/320/EC of 31 March 2004, free of bovine tuberculosis, sporadic findings, Czech Rebuplic.
Pfeiffer, D.U. TB: current status and control: a view from the outside. Cattle Practice. 2005; 13 (4): 305-311. ISSN: 0969-1251
NAL Call Number: SF961.C37
Descriptors: cattle, Mycobacterium bovis, eradication and control concerns, disease levels, UK.
Pollock, J.M.; Skuce, R.A.; Mackie, D.P.; Neill, S.D. Bovine tuberculosis: research in Northern Ireland. Cattle Practice. 2005; 13 (4): 301-303. ISSN: 0969-1251
Descriptors: badgers (Meles meles), cattle, Mycobacterium bovis, Northern Ireland.
Pollock, J.M.; Welsh, M.D.; McNair, J. Immune responses in bovine tuberculosis: towards new strategies for the diagnosis and control of disease. Veterinary Immunology and Immunopathology. 2005 Oct. 18; 108 (1-2): 37-43. ISSN: 0165-2427. Note: Paper presented at the 7th International Veterinary Immunology Symposium Held July 25-30, 2004, Quebec, Canada.
URL:http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number: SF757.2.V38
Descriptors: cattle, bovine tuberculosis, immune response, disease diagnosis, disease control, Mycobacterium bovis, tuberculin, vaccines, diagnostic techniques, disease detection, literature reviews.
Sattelmair, H. Die Tuberkulose des Rindes - ein Beitrag zur Geschichte der Haustierkrankheiten. [Tuberculosis of the Cattle - A Contribution to the History of Diseases in Domesticated Animals.] Freie Universitat Berlin. Berlin, Germany. 2005. 211 pp. Note: A thesis in German with an English summary.
Descriptors: historical review, Mycobacterium bovis, cattle, clinical aspects of the disease, pathogenesis, epidemiology, epidemics, disease control, tuberculosis in animals, zoonotic diseases.
Skinner, Margot A.; Wedlock, D. Neil; de Lisle, Geoffrey W.; Cooke, Michßele M.; Tascon, Ricardo E.; Ferraz, Jose C.; Lowrie, Douglas B.; Vordermeier, H. Martin; Hewinson, R. Glyn; Buddle, Bryce M. The order of prime-boost vaccination of neonatal calves with Mycobacterium bovis BCG and a DNA vaccine encoding mycobacterial proteins Hsp65, Hsp70, and Apa is not critical for enhancing protection against bovine tuberculosis. Infection and Immunity. 2005; 73 (7): 4441-4444. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1.I57
Abstract: Priming neonatal calves at birth with a Mycobacterium bovis bacillus Calmette-Guerin (BCG) vaccine and boosting with a DNA vaccine consisting of plasmids encoding mycobacterial antigens Hsp65, Hsp70, and Apa or the reverse prime-boost sequence induced similar levels of protection against experimental challenge with Mycobacterium bovis. When M. bovis was isolated from a thoracic lymph node following challenge, the two groups of calves given the prime-boost regimen had significantly lower numbers of M. bovis isolates than those vaccinated with BCG alone. These observations suggest that the exact sequence of administration of a prime-boost vaccination regimen in a neonatal animal model is not critical to the development of immunity.
Descriptors: Mycobacterium bovis, neonatal animal model, calves, prime-boost vaccination regimen, development of immunity.
Underwood, S.C.; Carfagnini, J.C. Comparacion de dos criterios para la interpretacion de la prueba tuberculinica cervical comparativa en caprinos. [Comparison between two criterions to interpret the tuberculin cervical comparative test in caprines.] Revista Argentina de Produccion Animal. 2005; 25 (3/4): 199-205 ISSN: 0326-0550. Note: In Spanish with an English summary.
Descriptors: goats, caprine test, compare test results between cattle and goats, cervical comparative test, OOIE interpretation rules, criterion proposed by Garcia Marin and Gutierrez Cancela, differences were found, Argentina.
Veeregowda, B.M.; Isloor, S.; Leena, G.; Rajsekhar, M. Assessment of an enzyme linked immunosorbent assay for detection of bovine tuberculosis. Journal of Veterinary Public Health. 2005; 3(2): 111-114. ISSN: 0972-7485
Descriptors: cattle, Mycobacterium bovis, serum antibody detection, avidin-biotin ELISA, sensitivity and specificity were low, not suitable for a diagnostic tool.
Villarreal-Ramos, B.; McAulay, M.; Reed, S.; Prentice, H.; Coffey, T.; Cherleston, B.; Howard, C. Effect of the nature of the antigen on the boosting of responses to mycobacteria in M bovis BCG vaccinated cattle. Immunology. 2005; 116 (Suppl. 1): 22. ISSN: 0019-2805. Note: A meeting abstract.
URL: http://www.blackwellpublishing.com/journal.asp?ref=0019-2805&site=1
NAL Call Number: 448.3 IM6
Descriptors: cattle, antibody, antigen, BCG, immunologic drug, immunostimulant drug, vaccine, Mycobacterium bovis infection, bovine tuberculosis, animal pathogens, prevention and control, Th1 cell, immune system, Th2 cell.
Vordermeier, M.; Buddle, B.; Hewinson, R.G. Development of cattle vaccines against bovine tuberculosis. Research in Veterinary Science. 2005; 78 (Suppl. A): 11-12. ISSN: 0034-5288. Note: A meeting abstract. 59th Annual Conference of the Association for Veterinary Teaching and Research Work, Scarborough, England; March 21 -23, 2005.
URL:http://www.elsevier.com/wps/find/journaldescription.cws_home/623070/description#description
NAL Call Number: 41.8 R312
Descriptors: cattle, Mycobacterium tuberculosis, Mycobacterium bovis, DNA, vaccine antigens, tuberculosis vaccine, immunostimulant drug.
Vordermeier,-M; Goodchild, A; Clifton-Hadley, R; Rua, R. de la. The interferon-gamma field trial: background, principles and progress. Cattle Practice. 2005; 13 (4): 323-325. ISSN: 0969-1251. Note: Reprinted from Veterinary Record. 2004; 155: 37-38.
NAL Call Number: SF961.C37
Descriptors: cattle, Mycobacterium bovis, diagnosis, diagnostic techniques, disease prevalence, epidemiology, interferon, skin tests, tuberculin test, UK.
Wangoo, A.; Rhodes, S.; Gough, G.; Inglut, S.; Ackbar, R.; Spencer, Y.; Hewinson, R.G.; Vordermeier, M.; Johnson, L. Low dose Mycobacterium bovis infection in cattle results in pathology resembling to that of high dose infection. Research in Veterinary Science. 2005; 78 (Suppl. A): 41. ISSN: 0034-5288 . Note: Meeting abstract. 59th Annual Conference of the Association for Veterinary Teaching and Research Work, Scarborough, England; March 21 -23, 2005
URL:http://www.elsevier.com/wps/find/journaldescription.cws_home/623070/description#description
NAL Call Number: 41.8 R312
Descriptors: cattle, Mycobacterium bovis, low dose infection, comparison to high dose infection, pathology, etiology, transmission.
Wangoo, A.; Johnson, L.; Gough, J.; Ackbar, R.; Inglut, S.; Hicks, D.; Spencer, Y.; Hewinson, G.; Vordermeier, M. Advanced granulomatous lesions in Mycobacterium bovis-infected cattle are associated with increased expression of type I procollagen, gamma delta (WC1+) T cells and CD 68+ cells. Journal of Comparative Pathology. 2005 Nov.; 133 (4): 223-234. ISSN: 0021-9975
NAL Call Number: 41.8 J82
Descriptors: granuloma, disease course, gene expression, Mycobacterium bovis, type I procollagen, gamma delta (WC1+) T cells, CD 68+ cells.
Wedlock, D. Neil; Denis, Michel; Skinner, Margot A.; Koach, Jessica; de Lisle, Geoffrey W.; Vordermeier, H. Martin; Hewinson, R. Glyn; van Drunen Little van den Hurk, Sylvia; Babiuk, Lorne A.; Hecker, Rolf; Buddle, Bryce M. Vaccination of cattle with a CpG oligodeoxynucleotide-formulated mycobacterial protein vaccine and Mycobacterium bovis BCG induces levels of protection against bovine tuberculosis superior to those induced by vaccination with BCG Alone. Infection and Immunity. 2005; 73 (6): 3540-3546. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1.I57
Abstract: The development of a subunit protein vaccine for bovine tuberculosis which could be used either in combination with Mycobacterium bovis BCG (to improve the efficacy of that vaccine) or alone would offer significant advantages over currently available strategies. A study was conducted with cattle to determine the protective efficacy of a strategy based on concurrent immunization with an M. bovis culture filtrate (CFP) vaccine and BCG compared to vaccination with either vaccine alone. One group of calves (10 animals per group) was vaccinated subcutaneously with CFP formulated with Emulsigen and combined with a CpG oligodeoxynucleotide (ODN). A second group was vaccinated with both the CFP vaccine and BCG injected at adjacent sites (CFP-BCG). One further group was vaccinated subcutaneously with BCG, while another group served as nonvaccinated control animals. Vaccination with CFP-BCG induced levels of antigen-specific gamma interferon (IFN-[gamma]) and interleukin-2 (IL-2) in whole-blood cultures that were higher than those induced by vaccination with BCG alone. The combination of CFP and BCG did not enhance the production of antibodies to M. bovis CFP compared to vaccination with CFP alone. Vaccination with CFP alone led to delayed antigen-specific IFN-[gamma] and IL-2 responses. Vaccination with CFP-BCG induced a high level of protection against an intratracheal challenge with virulent M. bovis, based on a significant enhancement of six pathological and microbiological parameters of protection compared with the nonvaccinated group. In contrast, vaccination with BCG alone induced a significant enhancement of protection in only one parameter, while CFP alone induced no protection. These results suggest that a combination of a CpG ODN-formulated protein vaccine and BCG offers better protection against bovine tuberculosis than does BCG alone.
Descriptors: bovine tuberculosis, subunit protein vaccine, development, Mycobacterium bovis, culture filtrate-based vaccine, BCG vaccine, calves, experimental model, efficacy of several regimens.
Wedlock, D.N.; Skinner, M.A.; De Lisle, G.W.; Vordermeier, H.M.; Hewinson, R.G.; Hecker, R.; Van Drunen-Little van den Hurk, S.; Babiuk, L.A.; Buddle, B.M. Vaccination of cattle with Mycobacterium bovis culture filtrate proteins and CpG oligodeoxynucleotides induces protection against bovine tuberculosis. Veterinary Immunology and Immunopathology. 2005; 106 (1-2) 53-63. ISSN: 0165-2427
URL: http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number: SF757.2.V38
Descriptors: cattle, Mycobacterium bovis, bovine tuberculosis, vaccination, culture filtrates, nucleotide sequences, disease prevention, vaccine adjuvants, immunomodulators, immune response, organic acids and salts, granulocyte macrophage colony stimulating factor, recombinant proteins, interferons, cell mediated immunity, bacterial antigens, subunit vaccines, molecular sequence data, CpG islands, polyinosinic acid, polycytidylic acid.
Welsh, Michael D.; Cunningham, Rodat T.; Corbett, David M.; Girvin, R Martyn; McNair, James; Skuce, Robin A.; Bryson, David G.; Pollock, John M. Influence of pathological progression on the balance between cellular and humoral immune responses in bovine tuberculosis. Immunology. 2005; 114 (1): 101-111. ISSN: 0019-2805. Online ISSN: 1365-2567
URL: http://www.blackwellpublishing.com/journal.asp?ref=0019-2805&site=1
NAL Call Number: 448.3 IM6
Descriptors: cattle, Mycobacterium bovis, supressed cell-mediated immune responses, and increased humoral responses, study on balance of evolving immune responses, pathogenesis, CD4 T-cell clones, increased ratio of Th0 [interleukin-4-positive/interferon-gamma-positive (IL-4(+)/IFN-gamma(+))] clones to Th1 (IFN-gamma(+)) clones.
Whelan, A.O.; Coad, M.; Cockle, P.J. Hewinson, R.G. Gordon, S; Vordermeier, H.M. Comparative virulence and immunology of M. tuberculosis and M. bovis in cattle. Immunology. 2005; 116 (Suppl. 1): 77. ISSN: 0019-2805. Note: Abstract, Annual Congress of the British Society for Immunology, Harrogate, England; December 06 -09, 2005
URL: http://www.blackwellpublishing.com/journal.asp?ref=0019-2805&site=1
NAL Call Number: 448.3 IM6
Descriptors: cattle, humans, zoonotic diseases, bacterial pathogens, Mycobacterium tuberculosis Rv3879c-gene, Mycobacterium bovis Rv3879c gene, interferon-gamma; antigen, PPD, ESAT6, CFP10.
Winthrop, K.L.; Scott, J.; Brown, D; Jay, M.T.; Rios, R.; Mase, S.; Richardson, D.; Edmonson, A.; MacLean, M.; Flood, J. Investigation of human contacts: a Mycobacterium bovis outbreak among cattle at a California dairy. International Journal of Tuberculosis and Lung Disease. 2005; 9 (7): 809-813. ISSN: 1027-3719. Note: In English with summaries in French and Spanish.
Descriptors: dairy cattle, Mycobacterium bovis, dairy farms, occupational health study, working with infection animals, drinking raw milk, dairy workers, families, slaughterhouse workers, tuberculin skin test, disease-transmission; Mexican-American ethnic groups, human diseases milk-borne diseases, outbreaks, risk factors, tuberculosis, zoonoses, California, US.
Woodroffe, R.; Donnelly, C.A.; Johnston, W.T.; Bourne, F.J.; Cheeseman, C.L.; Clifton-Hadley, R.S.; Cox, D.R.; Gettinby, G.; Hewinson, R.G.; Le Fevre, A.M. Spatial association of Mycobacterium bovis infection in cattle and badgers Meles meles. Journal of Applied Ecology. 2005 Oct 42 (5 ): 852-862. ISSN: 0021-8901
URL: http://www.blackwellpublishing.com/journal.asp?ref=0021-8901&site=1
NAL Call Number: 410 J828
Descriptors: cattle, badgers (Meles Meles), Mycobacterium bovis, bovine tuberculosis, strains, zoonoses, spatial distribution, disease prevalence, disease reservoirs, disease transmission, disease control, cluster analysis, Great Britain.
Woolhouse, M.E.J. Dangers of moving cows. Nature. 2005; 435 (7041): 431-432. ISSN: 0028-0836
URL: http://www.nature.com/index.html.
NAL Call Number: 472 N21
Descriptors: cattle, bovine tuberculosis, Mycobacterium bovis, animal transport, movement of animals, geographical distribution, disease transmission, badgers, epidemiology, Great-Britain.
Zanini, M.S.; Moreira, E.C.; Salas, C.E.; Lopes, M.T.P.; Barouni, A.S.; Roxo, E.; Telles, M.A.; Zumarraga, M.J. Molecular typing of Mycobacterium bovis isolates from south-east Brazil by spoligotyping and RFLP. Journal of Veterinary Medicine Series B. 2005 Apr; 52 (3) 129-133. ISSN: 0931-1793
NAL Call Number: 41.8 Z52
Descriptors: dairy cattle, beef cattle, bovine tuberculosis, Mycobacterium bovis, pathogen identification, microbial genetics, strains, genetic polymorphism, molecular genetics, antibiotic resistance, diagnostic techniques, spoligotyping, ethionamide rifampicin, isoniazid, strain differences, disease surveillance, diagnostic-techniques, post slaughter tissue collection, identification of 163 strains, polymerase chain reaction (PCR) and microbiological tests, 252 tuberculous-like lesions, 3 genotyping techniques, IS6110-restriction fragment length polymorphism (RFLP), polymorphic guanine-cytosine-rich sequence (PGRS)-RFLP and direct repeat (DR)-spoligotyping, fails to show a correlation between main cluster found by the 3 techniques, Brazil.
2004
Allsopp, B.A.; Babiuk, L.A.; Babiuk, S.L. Vaccination: an approach to the control of infectious diseases. In: J.A.W. Coetzer and R. C. Tustin (editors). Infectious Diseases of Livestock, Volume One. 2004; (Ed.2): Oxford University Press, Oxford, UK. 2004: 239-247. ISBN: 01915761693. Note: A book chapter.
Descriptors: livestock animals, animal diseases, Escherichia coli, Listeria monocytogenes, Mycobacterium bovis, disease control measures, vaccination, live vaccines, DNA vaccines, inactivated vaccines, BCG vaccines, passive immunization, disease prevention and control.
Asseged, B.; Woldesenbet, Z.; Yimer, E.; Lemma, E. Evaluation of abattoir inspection for the diagnosis of Mycobacterium bovis infection in cattle at Addis Ababa abattoir. Tropical Animal Health and Production. 2004; 36 (6): 537-546. ISSN: 0049-4747. Note: In English with summaries in French and Spanish.
URL: http://www.springerlink.com/content/103008/
NAL Call Number: SF601-.T7
Descriptors: cattle, Mycobacterium bovis, slaughter, meat inspection, bovine tuberculosis, Ethiopia.
Baptista, F.; Moreira, E.C.; Santos, W.L.M.; Naveda, L.A.B. Prevalencia da tuberculose em bovinos abatidos em Minas Gerais. [Prevalence of tuberculosis in cattle slaughtered in Minas Gerais, Brazil.] Arquivo Brasileiro de Medicina Veterinaria e Zootecnia. 2004; 56 (5): 577-580. ISSN: 0102-0935. Note: In Portuguese with an English summary.
Descriptors: humans, slaughter cattle survey, Mycobacterium bovis disease levels, disease prevalence, epidemiology, geographical distribution, zoonoses, Minas Gerais, Brazil.
Belgium Federal Agency for the Safety of the Food Chain. Report on Zoonotic Agents in Belgium 2003: Working Group on Foodborne Infections and Intoxications. Published by the Federal Agency for the Safety of the Food Chain (FASFC). Brussels. 2004; 74 pp.
Descriptors: common disease agents, domestic and wild animals, zoonotic potential, Mycobacterium bovis, Brucella melitensis, Brucella abortus, Brucella suis, Salmonella spp., Trichinella spp., rabies virus, Campylobacter spp., Echinococcus granulosus, Echinococcus multilocularis, Listeria monocytogenes, Yersinia enterocolitica, verotoxin producing Escherichia coli O157:H7, Taenia saginata, Sarcocystis hominis, Sarcocystis suihominis, Toxoplasma gondii, food borne illness, clinical aspects, routes of infection, recommendations, numbers of animals slaughtered in 2003, Belgium.
Bengis, R.G.; Kock, R.A.; Thomson, G.R.; Bigalke, R.D. Infectious diseases of animals in sub-Saharan Africa: the wildlife/livestock interface. In: J.A.W. Coetzer and R.C. Tustin (editors). Infectious Diseases of Livestock, Volume One. 2004; (Ed.2). Oxford University Press. Oxford. 2004: 225-238. ISBN: 01915761693. Note: A book chapter.
Descriptors: cattle, goats, pigs, horses, dogs, wildlife diseases, ruminants, Syncerus caffer, animal diseases, epidemics, African horse sickness, African swine fever, anthrax, brucellosis, epidemiology, foot and mouth disease, bovine tuberculosis, malignant catarrhal fever, rabies, Rift Valley fever, rinderpest, trypanosomiasis, etc.
Collins, J.D.; Wall, P.G. Food safety and animal production systems: controlling zoonoses at farm level. Revue Scientifique et Technique Office International des Epizooties. 2004; 23 (2): 685-700. ISSN: 0253-1933. ISBN: 9290446218. Note: In English with Spanish and French summaries
Descriptors: Brucella abortus, Campylobacter, Escherichia coli, Listeria monocytogenes, Mycobacterium avium ssp paratuberculosis, Mycobacterium bovis, Salmonella, Toxoplasma, Trichinella spiralis, Yersinia enterocolitica, abortion, animal production, disease control, disease prevention, epidemiology, feeds, food chains, food contamination, food safety, hygiene, paratuberculosis, risk assessment, selection pressure; stress to animals in transport, tuberculosis, zoonoses.
Cvetnic, Z.; Spiic, S.; Katalinic-Jankovic, V.; Capek, B.; Habrun, B.; Mitak, M. Primjena metode DNK u dijagnostici i identifikaciji kompleksa Mycobacterium tuberculosis u domacih zivotinja. [Application of a DNA method for the diagnosis and identification of Mycobacterium tuberculosis complex in domestic animals.] Veterinarska Stanica. 2004; 35 (5/6): 261-268. ISSN: 0350-7149. Note: In Croatian with an English summary.
Descriptors: cows, pigs, tuberculosis, clinical aspects, animal slaughtered, Mycobacterium bovis, Mycobacterium spp., diagnosis, multiplication of DNA sequence of the gene coding 65kD antigen, PCR, Croatia, Yugoslavia, Serbia, Montenegro.
Diguimbaye, C.; Schelling, E.; Pfyffer, G.E.; Baggi, F.; Ngandolo, R.; Ndoutamia, G.; Tanner, M.; Zinsstag, J. Premiers isolements de mycobacteries tuberculeuses chez l'homme et l'animal au Tchad. [First isolation of tuberculous mycobacteria in man and animals in Chad.] Medecine Tropicale. 2004; 64 (5): 482-485. ISSN: 0025-682X. Note: In French with an English summary.
Descriptors: first isolation and identification of Mycobacterium bovis, Mycobacterium tuberculosis, antibiotic resistance, pyrazinamide, control policies needed, Chad.
Erler, W.; Martin, G.; Sachse, K.; Naumann, L.; Kahlau, D.; Beer, J.; Bartos, M.; Nagy, G.; Cvetnic, Z.; Zolnir-Dovc, M.; Pavlik, I. Molecular fingerprinting of Mycobacterium bovis subsp. caprae isolates from Central Europe. Journal of Clinical Microbiology. 2004; 42 (5): 2234-2238. ISSN: 095-1137
URL: http://jcm.asm.org/cgi/content/short/42/5/2234
Descriptors: cattle, humans, Mycobacterium bovis ssp caprae, 79 European isolates, dissemination of pathogen, spoligotyping, ES6110 RFLP analysis, type C1 predominant, 11 different spoligotypes, 43 different RFLP types identified, DNA fingerprinting, zoonotic diseases.
Fritsche, A.; Engel, R.; Buhl, D.; Zellweger, J.P. Mycobacterium bovis tuberculosis: from animal to man and back. International Journal of Tuberculosis and Lung Disease. 2004; 8 (7): 903-904. ISSN: 1027-3719. Note: In English with French and Spanish summaries.
Descriptors: humans, cattle, other infected animals, Mycobacterium bovis, strains, zoonotic disease, disease transmission from animal to human and back to animal, case reports, clinical aspects, disease course, disease transmission, exposure, human diseases, strains, tuberculosis, Switzerland.
Gormley, E.; Doyle, M.B.; McGill, K.; Costello, E.; Good, M.; Collins, J.D. The effect of the tuberculin test and the consequences of a delay in blood culture on the sensitivity of a gamma-interferon assay for the detection of Mycobacterium bovis infection in cattle. Veterinary Immunology and Immunopathology. 2004; 102 (4): 413-420. ISSN: 0165-2427
URL: http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number: SF757.2.V38
Descriptors: cattle, tuberculin testing, Mycobacterium bovis, gamma interferon assay, detection of Mycobacterium bovis, blood culture.
Gunn-Moore, D. Investigating feline tuberculosis. Veterinary Times. 2004; 34 (13): 10. ISSN: 1352-9374
Descriptors: cats, cattle, humans, Mycobacterium avium, Mycobacterium bovis, Mycobacterium microti, disease prevalence, disease transmission between species, epidemiology, risk factors, disease spread, zoonoses.
Joardar, S.N.; Ram, G.C.; Goswami, T.K. Kinetics of seroreactivity of Mycobacterium bovis AN5 culture filtrate antigens in experimental bovine tuberculosis. Indian Journal of Animal Health. 2004; 43(1): 19-26. ISSN: 0019-5057
Descriptors: Mycobacterium bovis AN5, serodiagnosis, kinetics of seroreactivity, cattle, experimental infection, antibody level/titre, ELISA, 0-45 days post inoculation, sensitized animals, Western blot analysis, various polypeptide weights, immunodominant polypeptides.
Jordao Junior, C.M. Mycobacteria research in water buffalo milk. Revista do Instituto Adolfo Lutz. 2004; 63 (2): 273. ISSN: 0073-9855
Descriptors: water buffalo, Bubalus bubalis, milk products, microflora in milk, humans, zoonotic diseases, Mycobacterium intracellulare, Mycobacterium simiae, Mycobacterium bovis, strain JI321 e JB22, strain INS eINS2, strain AN5, Mycobacterium flavenscens.
Katoch, R.C.; Madhumeet Singh; Subhash Verma; Gupta, V.K.; Mandeep Sharma; Vineeta Almadi. Genital tuberculosis in a Jersey crossbred cow. Indian Veterinary Journal. 2004; 81(2): 216-217. ISSN: 0019-6479
NAL Call Number: 41.8 IN2
Descriptors: cattle, Jersey cross bred cow, Mycobacterium bovis, Staphylococcus aureus, genital area lesions, histopathology, diagnosis mixed infections, case reports, clinical aspects, Himachal Pradesh, India.
Koo, Hye Cheong; Park, Yong Ho; Ahn, Jongsam; Waters, W. Ray; Hamilton, Mary Jo; Barrington, George; Mosaad, Abdelaziz A.; Palmer, Mitch V.; Shin, Sang; Davis, William C. New latex bead agglutination assay for differential diagnosis of cattle infected with Mycobacterium bovis and Myobacterium avium subsp. paratuberculosis. Clinical and Diagnostic Laboratory Immunology. 2004; 11 (6): 1070-1074. ISSN: 1071-412X
Descriptors: cattle, identification of animals infected with Mycobacterium bovis, Mycobacterium avium ssp. paratuberculosis, current assays not sensitive and specific to identify diseased animals, latex bead agglutination assay (LBAA) using specific immunodominant epitope (ESAT6-p) of M. bovis, compared assay to culture method and skin test, experimental infection and non-infected animals, species specific diagnosis, sera testing, data suggest a rapid, sensitive and specific assay can be developed.
URL: http://hdl.handle.net/1030.28/NAL0000002e
NAL Call Number: aHV4701.A94 no. 2004-01
Abstract: The focus of this publication is on information related to tubercular diseases of animals caused by the bacterial genus Mycobacterium. Livestock diseases are mostly caused by Mycobacterium bovis and the Mycobacterium tuberculosis complex. Many species of animals are included: large ruminants, wildlife, wild animals as disease reservoirs, deer, elephants, birds, fish, etc. Topics are varied and include clinical aspects of the disease, the disease process, disease prevention and control, vaccines, immunology, bacterial genetics, zoonotic aspects, etc.
Diseases: tuberculosis in animals, bibliography, Mycobacterium sp, Mycobacterium avium, Mycobacterium bovis, zoonoses, production animals, zoo animals, wild animals, disease control, Mycobacterium tuberculosis complex, microbial genetics, disease incidence worldwide, control programs worldwide, immune response, wild animal vectors, treatments, animal disease models, aquatic animals, diagnostic methods, disease pathology, disease incidence worldwide.
Laval, G.; Ameni, G. Prevalence of bovine tuberculosis in zebu cattle under traditional animal husbandry in Boji district of western Ethiopia. Revue de Medecine Veterinaire. 2004; 155 (10): 494-499. ISSN: 0035-1555. Note: In English with an English summary.
Descriptors: zebu cattle, 62 herds, 780 individuals, animal prevalence, Mycobacterium bovis, single intradermal tuberculin test, comparative intradermal tuberculin test, risk of transmission to humans, Boji district, Ethiopia.
Lucca, E.; Canal, A.M.; Pachoud, J.C.; Gollan, A.; Bergamasco, M.; Latini, M.; Lopez, M.; Nicola, A.; Tomatis, I.; Scarpin, V. Diagnostico de tuberculosis bovina: correlacion entre pruebas diagnosticas. [Diagnosis of bovine tuberculosis: correlation between different diagnostic tests.] Veterinaria Argentina. 2004; 21 (203): 196-203. ISSN: 0326-4629. Note: In Spanish with an English summary.
Descriptors: dairy cattle; Mycobacterium bovis; blood sampling, diagnostic tests; correlation between tuberculin skin test, bacteriological cultures, microscopic lesions of lymph nodes and other organs, and interferon-gamma assay; interferon-gamma assay not sufficient at detecting M. bovis, Argentina.
Lutze-Wallace, C.; Chen, S.; Turcotte, C. Laboratory diagnosis of bovine tuberculosis in Canada for calendar year 2003. Canadian Veterinary Journal. 2004; 45(11): 915-916. ISSN: 0008-5286
URL: http://www.pubmedcentral.nih.gov/tocrender.fcgi?action=archive&journal=202
NAL Call Number: 41.8 R3224
Descriptors: cattle, bison, pigs, diagnosis, disease prevalence, disease surveys, epidemiological surveys, epidemiology, laboratory diagnosis, tuberculosis, wild animals, zoo animals, Mycobacterium avium subsp avium, Mycobacterium flavescens, Mycobacterium gordonae, Mycobacterium triviale, Cervus elaphus Canadensis, red deer, fallow deer, Mycobacterium avium, Mycobacterium avium subsp paratuberculosis, Mycobacterium bovis, Mycobacterium chelonae, Mycobacterium fortuitum, Mycobacterium marinum, Mycobacterium terrae, Mycobacterium xenopi, Odocoileus virginianus, pigs, Canada.
Lyashchenko, K.; Whelan, A.O.; Greenwald, R.; Pollock, J.M.; Andersen, P.; Hewinson, R.G.; Vordermeier, H.M. Association of tuberculin-boosted antibody responses with pathology and cell-mediated immunity in cattle vaccinated with Mycobacterium bovis BCG and infected with M. bovis. Infection and Immunity. 2004; 72 (5): 2462-2467. ISSN: 0019-9567
URL: http://iai.asm.org/cgi/content/full/72/5/2462
NAL Call Number: QR1 I57
Abstract: Vaccine development and our understanding of the pathology of bovine tuberculosis in cattle would be greatly facilitated by definition of the immunological correlates of protection and/or pathology. In this study we analyzed humoral immune responses in Mycobacterium bovis BCG-vaccinated and control cattle (in particular, the relationship between the intradermal comparative tuberculin skin test and serum immunoglobulin G [IgG] responses) against a range of mycobacterial antigens (MPB59, MPB64, MPB70, MPB83, ESAT-6, CFP-10, Acr1, and PstS-1) by multiantigen print immunoassay and conventional enzyme-linked immunosorbent assay. Following M. bovis infection, the comparative tuberculin skin test strongly boosted IgG, IgG1, and IgG2 antibody responses, particularly against MPB83 and MPB70, in unvaccinated cattle but failed to boost these responses, or did so only weakly, in BCG-vaccinated calves. In addition, the skin test-induced increases in MPB83-specific IgG responses correlated positively with bacterial loads and ESAT-6-induced in vitro gamma interferon responses. In conclusion, both the negative correlation of skin test-enhanced MPB83-specific antibody responses with BCG-induced protection and their positive correlation with bacterial loads can serve as useful markers for vaccine efficacy after challenge.
Descriptors: cattle, Mycobacterium bovis, experimental infections, immune response, antibodies, antigens, cell mediated immunity, humoral immunity, IgG, immunization, interferon, tuberculin skin tests, vaccination, vaccines.
Mackintosh, C.G.; Lisle, G.W. de; Collins, D.M.; Griffin, J.F.T. Mycobacterial diseases of deer. New Zealand Veterinary Journal. 2004; 52 (4): 163-174. ISSN: 0048-0169
URL: http://www.vetjournal.org.nz/nzvet.html
NAL Call Number: 41.8 N483
Descriptors: captive farmed deer, Mycobacterium avium complex, Mycobacterium avium subsp paratuberculosis, Mycobacterium bovis, diagnosis, disease prevention and control, epidemiology, mycobacteria diseases, zoonotic diseases, paratuberculosis, literature reviews, New Zealand.
Magnano, G.; Urbani, C.; Schneider, M.; Giraudo, J. Tuberculosis caprina: comparacion entre animales positivos a la prueba de intradermorreaccion y la presencia de lesiones y/o aislamiento. [Tuberculosis in goats: comparison between positivity to the skin test, pathological lesions and bacteriological cultures.] Veterinaria Argentina. 2004; 21 (208): 570-576. ISSN: 0326-4629. Note: In Spanish with an English summary.
Descriptors: goats, Mycobacterium bovis, diagnostic testing, diagnostic techniques, disease survey, disease prevalence, reliability of skin tests, postmortem tissue sampling, in vitro culture, comparison study, animal pathology, Argentina.
Maue, Alexander C.; Waters, W. Ray; Palmer, Mitchell V.; Whipple, Diana L.; Minion, F. Chris; Brown, Wendy C.; Estes, D. Mark. CD80 and CD86, but not CD154, augment DNA vaccine-induced protection in experimental bovine tuberculosis. Vaccine. 2004; 23 (6): 769-779. ISSN: 0264-410X
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/30521/description#description
Descriptors: cattle, enhancing immune response, Mycobacterium bovis BCG, vaccination, aerosol challenge with virulent M. bovis, co stimulatory molecules, CD154, CD80, CD86, CpG-ODN, DNA vaccination, anti-infective drug, adverse effects, efficacy, intravenous administration; subunit DNA vaccine ESAT-6, interferon-gamma, disease prevention and control.
McCorry, T.P.; McCormick, C.M.; Hughes, M.S.; Pollock, J.M.; Neill, S.D. Mycobacterium nonchromogenicum in nasal mucus from cattle in a herd infected with bovine tuberculosis. Veterinary Microbiology. 2004; 99 (3/4): 281-285. ISSN: 0378-1135
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number: SF601.V44
Descriptors: cattle herds, Mycobacterium nonchromogenicum, Mycobacterium bovis, genotypes, nucleotide sequences, skin tests, blood sampling, antibody ELISA, interferon-gamma assay, radiometric culture of nasal mucus samples, DNA probe testing Accuprobe, M. tuberculosis PCR amplification, 16S rRNA PCR, sequence analysis, first report of M. nonchromogenicum in nasal mucus of cattle, zoonotic risks.
McKenzie, J.S..; Morris, R.S.; Pfeiffer, D.U.; Meenken, D.; Lambie, J. Application of GIS and landscape epidemiology to TB control in possums. GISVET' 04: Second International Conference on the Applications of GIS and Spatial Analysis to Veterinary Science, University of Guelph, Ontario, Canada, 23rd 25th June. 2004: 78-80. ISBN: 189951323X. Note: Published by Veterinary Laboratories Agency. Addlestone, UK
Abstract: The EpiCentre, of Massey University used a farm level land forms survey epidemiological techniques to identify habitat and topographic risk factors associated with the distribution of TB infected possum clusters, of residual possums following culling and possum TB risk. These results were to develop geographic models within a GIS using satellite-derived habitat data to facilitate a risk-based approach to TB management in New Zealand.
Descriptors: cattle, Mycobacterium bovis; brushtail possum (Trichosurus vulpecula), disease surveillance methods, wildlife disease reservoir, epidemiology, geographic information systems, GIS, New Zealand.
Mirsojev, D.M.; Drauschke, W. Spread of tuberculosis in cattle stocks in various areas of Tajikistan. Journal of Agriculture and Rural Development in the Tropics and Subtropics. 2004; 105 (2): 197-200. ISSN: 0041-3186. Note: In Russian with an English summary.
Descriptors: cattle, tuberculosis levels 1943-1994, Mycobacterium bovis, inadequate veterinary measures, insufficient diagnosis of cattle, lack of long term control of infected animals, disease prevention and control at the farm level, sanitation practices improved, zoonotic risks of transmission to humans, Republic of Tajikistan.
Mota, P.M.P.C.; Motta, P.M.C.; Lobato, F.C.F.; Lage, A.P.; Ribeiro, A.C.C.L.; Leite, R.C. Avaliacao do tratamento com isoniazida em bovinos infectados naturalmente pelo Mycobacterium bovis. [Evaluation of isoniazid treatment carried in cattle naturally infected with Mycobacterium bovis.] Arquivo Brasileiro de Medicina Veterinaria e Zootecnia. 2004; 56 (5): 581-588. ISSN: 0102-0935. Note: In Portuguese with an English summary.
Descriptors: naturally infected cattle herd, 240 animals, humans, Mycobacterium bovis, intermittent drug treatment, isoniazid, oral dosing 3x/week, zoonotic disease.
Nita, C. Diagnosticul tuberculozei la bovine in judetul Vaslui prin testul imunoenzimatic-procedeul sandwich pentru detectarea gamma-interferonului. [The diagnosis of bovine tuberculosis in Vaslui District by an enzyme immunoassay for detection of gamma-interferon.] Revista Romana de Medicina Veterinara. 2004; 14 (3): 149-154. ISSN: 1220-3173. Note: In Romanian with an English summary.
Descriptors: cattle, testing intradermal reaction, enzyme immunoassay follow up, gamma interferon, in vitro stimulated blood samples, diagnostic techniques, disease prevalence and control, Mycobacterium bovis, epidemiology, Strategic program for Supervision and Control of Bovine Tuberculosis, Vaslui District, Romania.
Norby, B.; Bartlett, P.C.; Fitzgerald, S.D.; Granger, L.M.; Bruning-Fann, C.S.; Whipple, D.L.; Payeur, J.B. The sensitivity of gross necropsy, caudal fold and comparative cervical tests for the diagnosis of bovine tuberculosis. Journal of Veterinary Diagnostic Investigation. 2004; 16 (2): 126-131. ISSN: 1040-6387
URL: http://jvdi.org/
NAL Call Number: SF774.J68
Descriptors: 22 cattle herds, Mycobacterium bovis, complement fixation tests, diagnosis, diagnostic techniques, diagnostic value of several tests, gross necropsy, histological exam, mycobacterial culture, PCR assay of samples suspected of bTb, sensitivity of caudal fold and comparative cervical skin tests, tests compared, disease control, culling, depopulation, zoonoses, northeast corner of Michigan’s lower peninsula.
Palmer, M.V.; Waters, W.R.; Whipple, D.L.; Slaughter, R.E.; Jones, S.L. Evaluation of an in vitro blood-based assay to detect production of interferon-gamma by Mycobacterium bovis-infected white-tailed deer (Odocoileus virginianus). Journal of Veterinary Diagnostic Investigation. 2004; 16 (1): 17-21. ISSN: 1040-6387
URL: http://jvdi.org/
NAL Call Number: SF774.J68
Descriptors: deer (Odocoileus virginianus), Mycobacterium bovis, captive Cervidae added to the USDA Uniform Methods and Rules for eradication of bovine tuberculosis, wild animals as a disease reservoir, testing potential of a new blood-based assay for Cervidae, animal welfare, reduced handling, stress and injury and death, experimental inoculation, 300 colony forming units. tonsillar crypts, young males and females, serial blood collection up to 307 days, analyzed for production of M. bovis, PPDb, M. avium PPDa, pokeweed mitogen or media alone, PPDb may serve diagnostic technique ante mortem, Michigan.
Pate, Mateja; Zdovc, Irena; Pirs, Tina; Krt, B.; Ocepek, M. Isolation and characterisation of Mycobacterium avium and Rhodococcus equi from granulomatou lesions of swine lymph nodes in Slovenia. Acta Veterinaria Hungarica. 2004; 52 (2): 143-150. ISSN: 0236-6290
Descriptors: cattle, swine, lymph nodes, mixed infections, Mycobacterium hominissuis (IS901-, IS1245+ genotype), Mycobacterium avium avium (IS901+, IS1245+ genotype), typed using IS1245, IS901 and FR300 PCR, Rhodococcus equi isolates, tested for virulence-associated antigens (VapA and VapB).
Pavlik, I.; Jahn, P.; Dvorska, L.; Bartos, M.; Novotny, L.; Halouzka, R. Mycobacterial infections in horses: a review of the literature. Veterinarni Medicina. 2004; 49 (11): 427-440. ISSN: 0375-8427
Descriptors: horses, mycobacterial infections, Mycobacterium avium complex, Mycobacterium tuberculosis, Mycobacterium avium ssp paratuberculosis, Mycobacterium bovis, Mycobacterium chelona, Mycobacterium fortuitum, Mycobacterium smegmatis, Mycobacterium terrae, Mycobacterium africanum, Mycobacterium microti, clinical signs, epidemiological relationships, atypical disease course, diagnosis, diagnostic techniques, disease-prevalence, disease transmission, epidemiology, histopathology, molecular genetics, risk-factors, serotypes, taxonomy, zoonoses, literature review, seen in Central Europe.
Perez, A; Debenedetti, R; Martinez-Vivot, M; Bernardelli, A.; Torres, P.; Ritacco, V. Tendencia de la tuberculosis porcina y validez de la inspeccion bromatologica para su deteccion en areas de produccion intensiva de la Argentina. [Swine tuberculosis in Argentina: the value of the bromatologic inspection in an intensive swine production area.] Revista de Medicina Veterinaria Buenos Aires. 2004; 85 (2): 61-64. ISSN: 0325-6391. Note: In Spanish with an English summary.
Descriptors: pigs, intensive production systems, Mycobacterium bovis, diagnosis, disease prevalence, disease control, post slaughter examinations, abattoirs, carcass condemnation, carcasses, disease control, disease surveys, disease transmission, epidemiology, histopathology, monitoring, Argentina.
Pun, M.B.; Prasai, T.P.; Mermagya-Dhakal; Jha, V.K.; Shrestha, K.B.; Jha, V.C.; Sato, T.; Morita, Y.; Kozawa, K.; Kimura, H. Single intradermal tuberculin tests of milking buffaloes and cows in Nepal. Veterinary Record (London). 2004; 154 (4): 124. ISSN: 0042-4900
URL: http://veterinaryrecord.bvapublications.com/
NAL Call Number: 41.8 V641
Descriptors: buffalo, cattle, cows, humans, Mycobacterium bovis, Mycobacterium tuberculosis, Mycobacterium africanum, Mycobacterium canetti, Mycobacterium microti, disease prevalence, disease transmission from animals to humans, zoonotic aspects, intradermal tuberculin test.
Retamal, P.I.; Abalos, P.E. Comparacion del ensayo de interferon gamma bovino con tecnicas tradicionales para el diagnostico de infeccion con Mycobacterium bovis en la Region Metropolitana de Chile. [Comparison of the bovine gamma-interferon assay with traditional techniques for detecting infection with Mycobacterium bovis.] Revista Colombiana de Ciencias Pecuarias. 2004; 17(3): 223-230. ISSN: 0120-0690. Note: In Spanish with an English summary.
Descriptors: cattle, bovine tuberculosis, Mycobacterium bovis, assays, detection, diagnosis, diagnostic techniques, interferon.
Ritelli, M.; Amadori, M.; Dondo, A.; Begni, B.; Zoppi, S.; Archetti, I.L. Combined use of the g-interferon and interleukin-2 receptor assays for diagnosis of bovine tuberculosis. Online Journal of Veterinary Research. 2004; 8: 16-21. ISSN: 1328-925X
Abstract: The g-interferon assay for bovine tuberculosis has reached wide acceptance in many countries. Yet, less than optimal specificity in some areas and a certain percentage of inconclusive results may affect this diagnostic technique. The problem of inconclusive results can be approached by a two-stage procedure, whereby peripheral blood mononuclear cells of g-interferon dubious samples are later analysed for expression of the interleukin-2 receptor; this had been validated as a further alternative marker of cell-mediated immunity in M. bovis-infected cattle. This way, the two assays are used sequentially on the same blood samples. As a result, further diagnostic information can be obtained without new blood samplings in the field. The results of the interleukin-2 receptor assay showed a high correlation with those of the g-interferon assay. Instead, there was no clear evidence of increased specificity under the conditions reported in this study.
Descriptors: cattle, Mycobacterium bovis, blood sampling, peripheral blood monomuclear cells, diagnostic assay, cell mediated immunity g-interferon, interleukin-2.
Scantlebury, M.; Hutchings, M.R.; Allcroft, D.J.; Harris, S. Risk of disease from wildlife reservoirs: badgers, cattle, and bovine tuberculosis. Journal of Dairy Science. 2004; 87 (2): 330-339. ISSN: 0022-0302
URL: http://jds.fass.org/contents-by-date.0.shtml
NAL Call Number: 44.8 J822
Descriptors: dairy cows, disease-reservoirs, wildlife livestock relations, badgers, Meles meles, Mycobacterium bovis, cattle grazing intensity, rotational grazing, strip grazing, animal behavior, risk assessment, England.
Shkaeva, N.A. Spread of bovine tuberculosis in a radiocontaminated area of Chelyabinsk Oblast. Russian Agricultural Sciences. 2004; (4): 30-32. ISSN: 1068-3674. Note: Translated from Doklady Rossiiskoi Akademii Sel'skokhozyaistvennykh Nauk (2004) No. 2: 41-43 (Ru). Publisher is AllertonPress, Inc, NY, NY
Descriptors: cattle, bovine tuberculosis, Mycobacterium bovis, relationship between epizootic situation and local radioactive waste contamination, soil pollution, study 1984-2002, high level of disease, remedial measures taken, positive relationship between disease and contamination, Russia.
Singh, B.B.; Sharma, S.; Kumar, H.; Dhand, N.K. Surveillance of diseases in organized dairy farms of Punjab. Journal of Research, Punjab Agricultural University. 2004; 41 (4): 490-494. ISSN: 0048-6019.
Descriptors: 3 dairy cattle farms, health status monitoring, disease prevalence, various diseases, brucellosis, infectious bovine rhinotracheitis, bovine tuberculosis 2.13%, Johne’s disease, theileriosis, trypanosomiasis, babesiosis, disease prevention, various disorders mentioned, Punjab, India.
Singh, S.K.; Rishendra Verma; Shah, D.H. Molecular fingerprinting of clinical isolates of Mycobacterium bovis and Mycobacterium tuberculosis from India by restriction fragment length polymorphism (RFLP). Journal of Veterinary Science. 2004; 5 (4): 331-335. ISSN: 1229-845X
Descriptors: humans, animals, Mycobacterium bovis, Mycobacterium tuberculosis, disease transmission between species, 40 mycobacterial strains, clinical and field isolates, RFLP, IS6110 and IS1081 probes, dairy cattle herds, patients, Indian Veterinary Research Institute campus, strains and species compared, India.
Smith, Robert M.M.; Drobniewski, Francis; Gibson, Andrea; Montague, John D.E.; Logan, Margaret N.; Hunt, David; Hewinson, Glyn; Salmon, Roland L.; O'Neill, Brian. Mycobacterium bovis infection, United Kingdom. Emerging Infectious Diseases. 2004; 10 (3): 539-541. ISSN: 1080-6040
URL: http://www.ncbi.nlm.nih.gov/sites/entrez?linkbar=plain&db=journals&term=1080-6040
NAL Call Number: RA648.5.E46
Descriptors: cattle, bacterial disease, zoonotic aspects, bovine tuberculosis transfer to humans, disease transmission, UK.
Sreedevi, B.; Krishnappa, G. Standardization of polymerase chain reaction for the detection of Mycobacterium tuberculosis complex organisms from bovines. Indian Journal of Animal Sciences. 2004; 74 (11): 1120-1123. ISSN: 0367-8318
NAL Call Number: 41.8 IN22
Descriptors: cattle, Mycobacterium tuberculosis complex, Mycobacterium bovis, Mycobacterium avium, Mycobacterium phlei, polymerase chain reaction, PCR, laboratory techniques, genetic techniques, biopsy, diagnostic techniques, Bangalore, India.
Teklu, A.; Asseged, B.; Yimer, E.; Gebeyehu, M.; Woldesenbet, Z. Tuberculous lesions not detected by routine abattoir inspection: the experience of the Hossana municipal abattoir, southern Ethiopia. Revue Scientifique et Technique Office International des Epizooties. 2004; 23 (3): 957-964. ISSN: 0253-1933.
Descriptors: detection of tuberculous cattle, routine post slaughter inspection, tissues collection, testing for Mycobacterium bovis, 4.5% found to have tuberculous lesions, routine plant inspections found fewer, lungs and thoracic lymph nodes, obvious need for a higher level of accuracy at necropsy.
Thom, M.; Morgan, J.H.; Hope, J.C.; Villarreal-Ramos, B.; Martin, M.; Howard, C.J. The effect of repeated tuberculin skin testing of cattle on immune responses and disease following experimental infection with Mycobacterium bovis. Veterinary Immunology and Immunopathology. 2004; 102 (4): 399-412. ISSN: 0165-2427
URL:http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number: SF757.2.V38
Descriptors: cattle, tuberculin testing, repeated skin testing, immune responses to testing, experimental infection with Mycobacterium bovis.
UK, Department for Environment Food and Rural Affairs. Zoonoses Report United Kingdom 2003. Published by the Department of Environment, Food and Rural Affrairs (DEFRA). 2004; 71 ISBN: 0855211407
URL: www.defra.gov.uk
Descriptors: humans cattle, livestock, avian influenza, bovine spongiform encephalopathy, Creutzfeldt Jakob disease, disease prevalence, disease surveys, disease transmission, epidemiology, foodborne diseases, vector borne diseases, waterborne diseases, West Nile fever, Borrelia, Campylobacter, Cryptosporidium, Escherichia coli, Hantavirus, Leptospira, Listeria, Mycobacterium bovis, Salmonella, Streptococcus, Toxocara, Toxoplasma, Trichinella, zoonoses, UK.
Vesosky, B.; Turner, O.C.; Turner, J.; Orme, I.M. Gamma interferon production by bovine gammadelta T cells following stimulation with mycobacterial mycolylarabinogalactan peptidoglycan. Infection and Immunity. 2004; 72 (8): 4612-4618. ISSN: 0019-9567
URL: http://iai.asm.org
NAL Call Number: QR1.I57
Abstract: A large percentage of lymphocytes in the blood of cattle express the gammadelta T-cell receptor, but specific functions for these cells have not yet been clearly defined. There is evidence, however, that human, murine, and bovine gammadelta T-cells have a role in the immune response to mycobacteria. This study investigated the ability of bovine gammadelta T-cells to expand and produce gamma interferon (IFN-gamma) in response to stimulation with mycobacterial products. Bovine gammadelta T-cells, isolated from the peripheral blood of healthy cattle, expanded following in vitro stimulation with live mycobacteria, mycobacterial crude cell wall extract, and Mycobacterium bovis culture filtrate proteins. In addition, purified gammadelta T-cells, co-cultured with purified monocytes and interleukin-2, consistently produced significant amounts of IFN-gamma in response to mycobacterial cell wall. The IFN-gamma-inducing component of the cell wall was further identified as a proteolytically resistant, non-sodium dodecyl sulfate-soluble component of the mycolylarabinogalactan peptidoglycan.
Descriptors: cattle, gamma interferon production, bovine gammadelta T cells, lymphocytes, ability to expand and produce IFN-gamma, stimulation, live mycobacteria, mycobacterial crude cell wall extract, Mycobacterium bovis culture filtrate, cell biochemistry.
Vordermeier, M.; Goodchild, A.; Clifton-Hadley, R.; Rua, R.de la. The interferon-gamma field trial: background, principles and progress. Veterinary Record. 2004; 155 (2): 37-38
Descriptors: cattle, Mycobacterium bovis, tuberculin skin tests, interferon-gamma test, latent infections, diagnostic techniques, disease course, histopathology, cell mediated immune response, immunodiagnosis.
Waters, W.R.; Nonnecke, B.J.; Palmer, M.V.; Robbe-Austermann, S.; Bannantine, J.P.; Stabel, J.R.; Whipple, D.L.; Payeur, J.B..; Estes, D.M.; Pitzer, J.E.; Minion, F.C. Use of recombinant ESAT-6:CFP-10 fusion protein for differentiation of infections of cattle by Mycobacterium bovis and by M. avium subsp. avium and M. avium subsp. paratuberculosis. Clinical and Diagnostic Laboratory Immunology. 2004; 11 (4): 729-735. ISSN: 1071-412X
Descriptors: cattle, Mycobacterium bovis, Mycobacterium avium ssp paratuberculosis, diagnosis, comparison, vitro responses, recombinant ESAT-6:CFP-10 (rESAT-6:CFP-10) fusion protein by blood leukocytes, cattle naturally exposed to Mycobacterium avium or experimentally challenged with Mycobacterium avium ssp. avium, Mycobacterium avium ssp. paratuberculosis compared to responses by ycobacterium bovis-infected cattle.
Yang, WeiChong; Jiao, XinAn. The advances in diagnosis techniques of bovine tuberculosis. Chinese Journal of Zoonoses. 2004; 20 (12): 1090-1093. ISSN: 1002-2694. Note: In Chinese.
Descriptors: Mycobacterium bovis, cattle disease, bovine tuberculosis, diagnostic techniques, animal experiments, ELISA, blood, lymphocytes, chromatography, cytokines, genetics, hyperplasia, immunity, immunology, interleukin 2; lipids, PCR, RFLP, molecular biology, sampling, screening, serology, tuberculin, Western blotting, antibody competitive tests, dot immunogold filtration assay, fluorescent polarization assay, interferon gamma, sensitivity, sequencing, smear tests.
Yei, Ku Song; Wu, Yeong Huey; Liao, Ming Huei; Liu, Hung Jen; Chang, Ching Dong; Shiau, Chung Jung. Difficulties in eradication of tuberculosis infected cows from the infected dairy herds in Taiwan. Taiwan Veterinary Journal. 2004; 30 (1): 56-63. ISSN: 1682-6485. Note: In Chinese.
Descriptors: cattle, Mycobacterium bovis, diagnostic testing, intradermal tuberculin test (ITT), gamma interferon test (IFN-gamma test), duplex polymerase chain reaction (duplex PCR), blood, nasal mucus samples, milk samples, difficulty eliminating disease, disease reservoirs on the farms, humans, dogs, cats, rats, nasal discharges and raw milk exposed calves, Taiwan.
2003
Adams, S.J.R. Badgers and bovine TB: bio-indicator
or source? Veterinary Times. 2003, 33 (9)
8-10. ISSN: 1352-9374
Descriptors: badgers, cattle, deer, Mycobacterium bovis, disease transmission patterns, disease vectors,
sentinel animals, vector potential, tuberculosis, reviews.
Ameni, G.; Amenu, K.; Tibbo, M. Bovine Tuberculosis:
Prevalence and risk factor assessment in cattle, and cattle owners in
Wuchali-Jida District,
NAL Call Number:
SF601.J63
Descriptors: Mycobacterium bovis,
Mycobacterium tuberculosis, zoonotic disease potential, cattle,
humans, risk factors, disease prevalence, risks of food consumption, poor sanitary
measures, lack of understanding about zoonotic potential,
Ethiopia.
Ameni, G.; Bonnet, P.; Tibbo, M. A cross-sectional study of bovine tuberculosis in selected dairy farms in
NAL Call Number: SF601.J63
Descriptors: 1171 dairy cattle, 12 dairy farms, Holstein, Zebu crosses, 46.8% animal prevalence, 91.7 herd prevalence, Mycobacterium bovis, comparative intradermal tuberculin test, bacteriological study, milk cultures, 548 animals positive, positive correlation between herd size and prevalence of M. bovis, farm and breed differences, management effects, sanitary measures, economic effect of disease, public health risks, husbandry practices, Ethiopia.
Bonesi, G.L.;
Scalone, B.C.V.; Okano, W.; Rosa, A. Lesoes hepaticas em bovinos
abatidos em matadouro—frigorifico.
[Hepatic lesions in cattle slaughtered in a refrigerator abattoir.] Higiene Alimentar.
2003, 17 (106) 78-83. Note: In Portuguese with an English summary.
Descriptors:
cattle, various diseases, post-slaughter examinations, lesions, 6.8% showed
liver abscesses; slaughter, teleangiectasis, hepatic
congestion, perihepatitis, cirrhosis, hepatitis,
hydatidosis, fasciolosis, tuberculosis,
Parna, Brazil.
Buddle, B.M.; Wedlock, D.N.; Parlane, N.A.; Corner, L.A.L.; De Lisle, G.W.; Skinner, M.A. Revaccination of neonatal calves with Mycobacterium bovis BCG reduces the level of protection against bovine tuberculosis induced by a single vaccination. Infection and Immunity. 2003; 71 (11): 6411-6419. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1.I57
Abstract: Cattle may provide a suitable model for testing ways of improving tuberculosis vaccine efficacy in human infants. A vaccination and challenge study was undertaken in calves to determine the optimal time to vaccinate neonatal animals with Mycobacterium bovis bacillus Calmette-Guerin (BCG) for protection against tuberculosis and to determine whether revaccination with BCG was beneficial. Calves (10 per group) were vaccinated with BCG within 8 h of birth or at 6 weeks of age, when immune responses to antigens of environmental mycobacteria were detectable, or vaccinated at birth and revaccinated at 6 weeks. A control group was not vaccinated. BCG vaccination at birth induced strong antigen-specific gamma interferon (IFN-gamma) and interleukin-2 (IL-2) responses and antigen-specific activation in CD4+, CD8+, and WC1+ gammadelta T-cell subsets from blood. The proportions of animals per group with macroscopic tuberculous lesions after challenge were 0/10 for BCG at birth, 1/9 for BCG at 6 weeks, 4/10 for the revaccinated group, and 10/10 for the nonvaccinated group. There was no significant difference in the levels of protection between groups vaccinated at birth or at 6 weeks, while animals vaccinated both at birth and at 6 weeks had significantly less protection than those vaccinated only at birth. The revaccinated calves that subsequently developed tuberculous lesions had significantly stronger IFN-gamma and IL-2 responses to bovine purified protein derivative after the BCG booster than those in the same group that did not develop lesions. The results indicated that BCG vaccination at birth induced a high level of immunity and that the sensitization of very young animals to antigens of environmental mycobacteria by 6 weeks of age did not affect the effectiveness of BCG. However, BCG revaccination of these young animals was contraindicated.
Descriptors: vaccination, clinical techniques, Friesian calves, Mycobacterium bovis, strain Pasteur 1173P2, strain Wag202, BCG vaccine, immune system, IFN-gamma/delta subsets, CD4+, CD8+, WC1+.
Buddle, B.M.; Pollock, J.M.; Skinner, M.A.; Wedlock, D.N. Development of vaccines to control bovine tuberculosis in cattle and relationship to vaccine development for other intracellular pathogens. International Journal for Parasitology. 2003; 33 (5-6): 555-566. ISSN: 0020-7519. Note: In the special issue: Vaccines in the 21st century: Expanding the Boundaries of Human and Veterinary Medicine. Edited by D. Brake.
NAL Call Number: QH547.I55
Abstract: Vaccination of cattle against bovine tuberculosis could be an important strategy for the control of disease either where there is a wildlife reservoir of Mycobacterium bovis infection or in developing countries where it is not economically feasible to implement a 'test and slaughter' control program. Advances in the understanding of protective immune responses to M. bovis infection in cattle and the advent of new molecular biological techniques, coupled with the sequencing of the M. bovis genome have provided opportunities for the rational development of improved tuberculosis vaccines. A number of new tuberculosis vaccines including attenuated M. bovis strains, killed mycobacteria, protein and DNA vaccines are under development and many are being assessed in cattle. Recent results have revealed several promising vaccine candidates and vaccination strategies. Ways of distinguishing between vaccinated and infected cattle are becoming available and the possibility of new approaches to the eradication of tuberculosis from domestic livestock is discussed. Similarities between the mechanisms of protective immunity against M. bovis and against other intracellular parasites continue to be found and discoveries from vaccine studies on bovine tuberculosis may provide helpful insights into requirements for vaccines against other intracellular pathogens.
Descriptors: Mycobacterium bovis, bovine tuberculosis, vaccine development, vaccines, immunity, vaccination cattle, BCG vaccine, literature reviews.
Cavirani, S.; Fanti, F.; Benecchi, M.; Calderaro, A.; Taddei, S.; Arcangeletti, C.; Medici, M.C.; Dettori, G.; Chezzi, C. Evaluation of susceptibility of Mycobacterium bovis to antituberculous drugs by radiometric BACTEC 460TB system. Microbiologica. 2003; 26 (2): 181-186. ISSN: 1121-7138
Descriptors: cattle, Mycobacterium bovis, strain susceptibility to antibiotics, post slaughter cattle, tissue sampling of lesions, 61 strains collected, 41 susceptible to isoniazid and rifampin, 13 resistant to isoniazid only, not strains resistant to rifampin only, 2 strains reistant to both drugs, Italy
Corner, L.A.L.; Stevenson, M.A.; Collins, D.M.;
Morris, R.S.
The re-emergence of Mycobacterium bovis infection in brushtail
possums (Trichosurus. vulpecula) after localised
possum eradication.
NAL Call Number: 41.8 N483
Descriptors: cattle, brushtail
possums, Mycobacterium bovis, infection patterns,
wild animal disease vectors and reservoirs, epidemiology, pest control, spatial
distribution patterns, tuberculosis, vector potential,
De Sousa, R.D.; Reis, D.O.; Guimaraes,
K.C.S.; Aquino, C.A.M. Linfonodos com maior frequencia
de localizacao para tuberculose bovina, em animais abatidos em um frigorifico sob inspecao federal, no municipio de
Uberlandia-MG. [Lymph nodes with the
greatest frequency of localization of bovine tuberculosis, in slaughtered
animals kept in a refrigerator under federal inspection, in the municipality
of Uberlandia-MG.] Higiene Alimentar. 2003, 17 (106) 35-39.
ISSN: 0101-9171 Note: In Portuguese with an English
summary.
Descriptors: cattle, Mycobacterium bovis, cattle bacterial
diseases, post-slaughter examination, disease incidence, tuberculosis, lesions,
lymph nodes, slaughter, Minas Gerais, Brazil.
Diaz-Otero, F.; Banda-Ruiz, V.; Jaramillo-Meza,
L.; Arriaga-Diaz, C.; Gonzalez-Salazar, D.; Estrada-Chavez,
C. Identification of Mycobacterium bovis
infected cattle by immunological and molecular methods. Veterinaria
NAL Call Number: SF604.V48
Descriptors:
dairy cattle, Mycobacterium bovis, antibodies, ELISA, immunodiagnosis,
immunological techniques, interferon, spoligotyping,
serological surveys, control, anergic animals,
Fletcher, J. Tuberculosis again? Deer
Farming. 2003, No.72, 20-24.
Descriptors:
deer, bovine tuberculosis, Mycobacterium, delayed type hypersensitivity,
epidemiology, skin tests, zoonoses.
Gallaher, E.; Kelly, L.; Pfeiffer, D.U.; Wooldridge, M. A quantitative risk assessment for badger to cattle transmission of Mycobacterium bovis. Proceedings of a meeting Society for Veterinary-Epidemiology and Preventive Medicine. [
NAL Call Number: SF780.9.S63
Descriptors: cattle, badgers, Mycobacterium bovis, bovine tuberculosis, disease transmission, risk assessment, mathematical models.
Garnett, B.T.; Roper, T.J.; Delahay, R.J. Use of cattle troughs by badgers (Meles meles). A potential route for the transmission of bovine tuberculosis (Mycobacterium bovis) to cattle. Applied Animal Behavior Science. 2003. 80 (1): 1-8. ISSN: 0168-1591
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503301/description#description
NAL Call Number: QL750.A6
Descriptors: badgers Meles meles, wild animals, cattle diseases, Mycobacterium bovis, cattle feed troughs height, wild animals, cattle-diseases, bovine tuberculosis, disease transmission, feces, vertebrate pests, wildlife/livestock interactions, wildlife food habits, United Kingdom.
Goodchild, A.V.; De La Rua Domenech, R.; Palmer, S.; Dale, J.; Gordon, S.V.; Hewinson, R.G.; Clifton-Hadley, R.S. Association between molecular type and the epidemiological features of Mycobacterium bovis in cattle. Proceedings of a meeting Society for Veterinary Epidemiology and Preventive Medicine. [
NAL Call Number: SF780.9.S63
Descriptors: cattle, Mycobacterium bovis, epidemiology, polymerase chain reaction, PCR, spoligotyping, variable number tandem repeats, spatial analysis.
Gormley, E.; Costello, E. Tuberculosis and badgers:
new approaches to diagnosis and control. Society
for Applied Microbiology Symposium Series. 2003,
No.32, 80S-86S.
NAL Call Number: QR1.S64 no. 32
Descriptors:
Eurasian badger, Meles meles,
wild animal disease reservoir, cattle, Mycobacterium bovis
infection, disease control eradication programs, diagnosis of disease
in badgers, profiles of disease episodes, possible vaccination, Ireland, Great
Britain.
Howard, C.J.;
Descriptors: cattle, livestock, dendritic cells, immune responses, stimulating naïve T cells, adaptive immunity, in vivo, ex-vivo, subpopulations of myeloid dendritic cells, cytokines, vaccination, Mycobacterium bovis.
Jian, MinHua; Xu, ZhaoHua;
Shao, WeiJie (et-al). Enzyme-linked
immunosorbent assay for detection of bovine IgG antibody to Mycobacterium tuberculosis. Chinese
Journal of Zoonoses. 2003, 19 (2) 81-82.
Note: In Chinese with an English summary.
Descriptors: cattle, Mycobacterium tuberculosis, antibodies, detection assay method,
blood serum, ELISA, IgG, lipopolysaccharides, monoclonal antibodies, auxiliary test
for intradermal test.
Koets, Ad.P. Mycobacterial heat shock proteins and the bovine immune system. In W. van Eden, Birkhaeuser Verlag,
Descriptors: bovines, Mycobacterium avium ssp. paratuberculosis, Mycobacterium bovis, heat shock proteins, immunodominant antigens, bacterial disease, gamma delta T-cell, blood and lymphatics, immune system, physiology.
Komaromy, A.M.; Andrew, S.E.; Brooks, D.E.; Detrisac, C.J.; Gelatt, K.N. Periocular sarcoid in a horse. Veterinary Ophthalmology. 2004; 7 (3): 141-146. ISSN: 1463-5216
NAL Call Number: SF891.V47
Descriptors: Thoroughbred mare, horse, case report, eyelid sarcoid, neoplasms, Mycobacterium bovis BCG.
Malone, F.E.;
Descriptors: sheep, cattle, Mycobacterium bovis, first evidence of transmission from cattle to sheep, animals with positive comparative intradermal tuberculin test, postmortem examination, tuberculous lesions, strain typing spoligotyping and variable tandem repeats typing, in vitro release of interferon-gamma, histopathology, Britain, Ireland, UK.
Martinez-Vivot, M.; Zumarraga, M.; Romano,
M.; Cataldi, A.; Diz,
L.; Guida, N.; Barboni, A.; Moras, E.V. Aplicacion del spoligotyping
para identificar el origen de reinfeccion de tuberculosis
bovina en un tambo de la provincia de Buenos Aires. [Usefulness
of spoligotyping to identify the origin of reinfection of bovine tuberculosis in a dairy farm in the
province of Buenos Aires.] Veterinaria
NAL Call Number: SF604.V463
Descriptors: dairy cattle, PPD intradermal test,
Mycobacterium bovis, infection source, spoligotyping test, disease survey, re-infection, tuberculous lesions,
Maue, Alex C.; Waters, W. Ray; Palmer, Mitch; Estes, D.Mark. Costimulatory molecules augment DNA vaccine-induced immunity to experimental bovine tuberculosis. FASEB Journal. 2003; 17 (7): C26. ISSN: 0892-6638. Note: Meeting abstract. 90th Anniversary Annual Meeting of the American Association of Immunologists, Denver, CO,
Descriptors: bovine tuberculosis, DNA vaccines, immunostimulant drug, mouse model, Mycobacterium bovis, co-stimulatory molecules, laboratory techniques, immune responses.
Milian-Suazo, F.;
Anaya-Escalera, A.M.; Gallegos-Torres, R.M. A review of M.
bovis BCG protection against TB in cattle and
other animals species. Preventive
Veterinary Medicine. 2003, 58 (1-2) 1-13.
NAL Call Number: SF601.P7
Descriptors:
cattle, Mycobacterium bovis BCG strain, disease
control, immunity, potency, reviews, tuberculosis vaccination, vaccine development.
Mota, P.M.P.C.; Motta, P.M.C.; Lobato, F.C.F.; Lage, A.P.; Ribeiro, A.C.C.L.; Leite, R.C. Avalaicao do tratamento com isoniazida em bovinos infectados naturalmente pelo Mycobacterium bovis. [Evaluation of the treatment with isoniazid carried out in bovines naturally infected with Mycobacterium bovis.] Arquivo Brasileiro de Medicina Veterinaria e Zootecnia. 2004; 56 (5): 581-588. ISSN: 0102-0935. Note: In Portuguese.
Descriptors: cattle, 240 animals, naturally infected herd, intermittent treatment with isoniazid, oral dosing of 3x/week, for 10 months, efficacy of the drug, treatment did not cause selection of drug resistant strains.
New
Zealand, Livestock Improvement Corporation Limited. Dairy
Statistics Livestock Improvement Corporation Limited, 2001-2002.
2003, 45 pp. Note: Published by the Livestock Improvement
Corporation Ltd, New Zealand Dairy Board; Hamilton;
Nonnecke, B. J.; Waters, W.R.; Foote: M.R.; Fowler,
R.M.; Horst, R.L.; Miller, B.L. Interferon-C and TNF-C secretion by mononuclear
leukocytes from peripheral blood of young and adult cattle, vaccinated with
Mycobacterium bovis BCG: Modulation by 1,25-dihydroxyvitamin
D3. International Journal
of Vitamin and Nutrition Research. 2003
73: 235-244.
Descriptors:
cattle, age goup comparison,
immunological response, white blood cells, peripheral blood sampling,
vaccination, Mycobacterium bovis BCG, effects
of 1,25-dihydroxyvitamin D3 .
Popluhar, L.; Hyzova, A. Tuberkuloza zvierat ako zoonoza aj ako antropozoonoza. [Tuberculosis of animals as zoonosis as well as anthropozoonosis.] Slovensky Veterinarsky Casopis. 2003; 28 (6): 38-39. ISSN: 1335-0099. Note: In Slovakian with an English summary.
Descriptors: elimination of animal tuberculosis, Mycobacterium bovis; Mycobacterium bovis BCG strain, BCG vaccine, vaccination, diagnosis, disease prevention and control, disease prevalence, zoonoses, Czechoslovakia
Rajeev Singh; Hari Shankar. Occurrence of tuberculosis at an organized cattle farm. Indian Veterinary Journal. 2003; 80 (11): 1100-1102. ISSN: 0019-6479
NAL Call Number: 41.8 IN2
Descriptors: 4696 cattle, Mycobacterium bovis, tuberculin testing for 3 years, 107 developed the disease, mortality rated recorded, age differences, disease prevalence, epidemiology,
Ramirez,
I.C.; Santillan, M.A.; Dante,V. The goat as an experimental
ruminant model for tuberculosis infection. Small
Ruminant Research. 2003, 47 (2) 113-116. ISSN: 0921-4488
NAL Call Number: SF380.I52
Abstract: Young goats were inoculated intratracheally with a low dose of Mycobacterium bovis to determine if they develop lesions similar to those seen in the natural disease in cattle. After 3 months, the challenge induced small lesions (< 1 cm diameter) localized in the lungs and pulmonary lymph nodes, similar to those seen in the natural cattle disease. All of the M. bovis-inoculated young goats showed strong cellular immune responses to bovine PPD. Results of the present study suggest that young goats can be used as animal models since a low dose challenge mimics the natural pathogenesis and pathology processes caused by M. bovis in cattle.
Descriptors: goats, animal model for disease, experimental infection, immune response,
kids, lesions, Mycobacterium bovis, tuberculosis.
Reid,
S.W.J. (ed); Menzies, F.D.
Society for Veterinary Epidemiology and Preventive Medicine.
Proceedings of a meeting held at University of Warwick,
Descriptors:
cattle, dogs, horses, Mycobacterium bovis,
epidemiology of bovine tuberculosis, injuries, FMD, heart diseases, mastitis,
satellite imagery, vaccination.
Roper,
T.J.; Garnett, B.T.; Delahay, R.J. Visits to
farm buildings and cattle troughs by badgers (Meles
meles): a potential route for transmission of
bovine tuberculosis (Mycobacterium bovis)
between badgers and cattle. Cattle Practice. 2003, 11 (1) 9-12. ISSN: 0969-1251
NAL Call Number: SF961.C37
Descriptors:
cattle, farms, tracking wild badgers, Meles meles, nighttime
visits to farms, climate, Mycobacterium bovis,
cats, foxes,disease transmission, feces, feed trough contamination,
rain, urine, diasese control.
Shirima, G.M.;
Kazwala, R.R.; Kambarage,
D.M. Prevalence of bovine tuberculosis in cattle in different farming systems
in the eastern zone of Tanzania. Preventive
Veterinary Medicine. 2003, 57 (3) 167-172. ISSN: 0167-5877
NAL Call Number: SF601.P7
Descriptors:
Mycobacterium bovis, Zebu cattle, free-ranging
system, internsive management, intradermal
tuberculin testing, incidence levels in two systems, disease survey, epidemiology,
Sreedevi, B.; Krishnappa, G. Pathogenesis of Mycobacterium tuberculosis isolated from cattle. Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases. 2003; 24 (1): 59-62. ISSN: 0970-9320
Descriptors: cattle, Mycobacterium, Mycobacterium avium, Mycobacterium bovis, Mycobacterium tuberculosis in cattle, different mycobacterial cultures, bovine macrophage cell cultures, NBT dye reduction test, disease transmission, levels of pathogenisity, phagocytosis, cattle as host organisms.
Sreedevi, B.; Krishnappa, G. Detection of Mycobacterium tuberculosis complex organisms in clinical samples of cattle by PCR and DNA probe methods. Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases. 2003; 24 (2): 167-171. ISSN: 0970-9320
Descriptors: cattle, Mycobacteriumj bovis, Mycobacterium phlei, Mycobacterium tuberculosis, Mycobacterium bovis, BCG, Mycobacterium avium, Mycobacterium avium ssp. paratuberculosis, Mycobacterium tuberculosis complex, diagnosis, diagnostic techniques, DNA probes, polymerase chain reaction, PCR,primers for IS6110, dot blot hybridization, tuberculin, tuberculosis, blood samples, milk samples, semen samples, Karnataka, India.
Usabiaga, J. Intersectoral Coordination-between-Health and Agriculture:-Zoonoses, Food Safety and Foot and Mouth Disease Final Report and Proceedings, XII-Inter American Meeting,
Descriptors: cattle, goats, humans, Mycobacterium bovis, Brucella, tuberculosis, animal health, brucellosis, disease prevention and control programs, disease prevalence, disease surveys, disease transmission, zoonotic diseases, epidemiology, public health, food contamination, food safety, international trade, participation, public health, quality controls, Latin America.
Vordermeier, H.M.;
Lowrie, D.B.; Hewinson,
R.G.
Improved immunogenicity of DNA vaccination with mycobacterial
HSP65 against bovine tuberculosis by protein boosting. Veterinary Microbiology. 2003, 93 (4) 349-359. ISSN:
0378-1135
NAL Call Number: SF601.V44
Descriptors:
cattle, adjuvants, bacterial antigens, cell mediated
immunity, disease control and prevention, Mycobacterium tuberculosis,
DNA, humoral immunity, IgG,
immune response, immunization, immunogenetics, interferon,
lymphocyte transformation, recombinant proteins, tuberculin, tuberculosis,
vaccination, vaccines.
Waters,
W.R.; Nonnecke, B.J.; Foote, M.R.; Maue, A.C.; Rahner, T.E.; Palmre, M.V. Whipple, D.L.: Horst, R.L.; Estes, D.M. Mycobacterium
bovis bacilli Calmette
Guerin vaccination of cattle, activation of bovine CD4+ and
CC-TCR+ cells and modulation by 1,25-dihydroxyvitamin D3
Tuberculosis, 2003, 83: 287-297.
Descriptors: cattle, Mycobacterium bovis BCG, vaccination,
immune response, CD4+ and CC-TCR+
cells, effects of dihydroxyvitamin D3
.
Waters, W.R.; Palmer, M.V.; Whipple, D.L; Carlson,
M.C.; Nonnecke, B.J. Diagnostic
implication of antigen-induced IFN-C, nitric oxide, and TNF-C production by
blood mononuclear cells from Mycobacterium bovis-infected
cattle. Clinical and Diagnostic Laboratory Immunology. 2003,
10: 960-966.
Descriptors:
cattle, Mycobacterium bovis, disease effects,
immunological response, mononuclear blood cells, white cells, antigen
induced responses, possible diagnostic value.
Wedlock, D.N.; Skinner, M.A.; Parlane, N.A.; Vordermeier, H.M.; Hewinson, R.G.; De Lisle, G.W.; Buddle, B.M. Vaccination with DNA vaccines encoding MPB70 or MPB83 or a MPB70 DNA prime-protein boost does not protect cattle against bovine tuberculosis. Tuberculosis (
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/638428/description?navopenmenu=-2
Descriptors: cattle, Mycobacterium bovis, bovine tuberculosis, DNA vaccines, control strategy, antigens, vaccinated with MPB83 DNA, MPB70 DNA, or DNA followed by MPB70 protein or injected with BCG or control plasmid DNA, did not induce immunity in calves.
Whelan, A.O.; Hope, J.C.; Howard, C.J.; Clifford, D.; Hewinson, R.G.; Vordermeier, H.M. Modulation of the bovine delayed-type hypersensitivity responses to defined mycobacterial antigens by a synthetic bacterial lipopeptide. Infection and Immunity. 2003; 71 (11): 6420-6425. ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number: QR1.I57
Abstract: The use of defined protein and peptide antigens can overcome specificity limitations of purified protein derivatives in the detection of bovine tuberculosis when the antigens are used in blood-based tests. Since the use of these specific antigens as skin test reagents could have practical advantages, we investigated the potential of Mycobacterium bovis-specific antigens to stimulate delayed-type hypersensitivity (DTH) responses in cattle experimentally infected with M. bovis. A cocktail of the recombinant antigens ESAT-6, MPB83, and MPB64 failed to stimulate in vivo DTH in cattle that had been experimentally infected with M. bovis despite the fact that the antigens were recognized in vitro by the same animals. However, it was possible to stimulate antigen-specific bovine DTH responses by using ESAT-6 in combination with a synthetic bacterial lipopeptide. This lipopeptide stimulated the release of the proinflammatory cytokine tumor necrosis factor alpha from monocyte-derived bovine dendritic cells in vitro, thereby providing a possible mechanism for its DTH-enhancing properties.
Descriptors: Mycobacterium bovis, detection methods, defined protein and peptide antigens, skin reagents, stimulation of delayed-type hypersensitivity, cattle synthetic bacterial lipopeptide.
Wilson, RT. Animal health
and disease control in the Usangu Wetland of Southwestern Tanzania.
Tropical
Animal Health and Production. 2003, 35 (1) 47-67. ISSN: 0049-4747
Note: In English with French and English summaries.
NAL Call Number: SF601.T7
Descriptors:
livestock, African swine fever, animal diseases, animal health, anthrax, cysticercosis, disease control, environmental factors, epidemiology,
foot and mouth disease, pleuropneumonia, rabies, Rift Valley fever, rinderpest, trypanosomiasis, tuberculosis,
veterinary services, African swine fever virus, Glossina, lumpy skin disease virus, Theileria
parva, Tanzania.
Zhang, XiYue; Wang, JunWei; Gao, YunHang; He, ZhaoYang. Comparison of three methods on detecting bovine tuberculosis in cattle ranch. Chinese Journal of Veterinary Science. 2003; 23 (6): 555-556. ISSN: 1005-4545. Note: In Chinese with an English summary.
Descriptors: 498 cattle, infected with Mycobacterium bovis, diagnostic techniques, diagnosis, bovine tuberculosis allergic reaction, Dot-IGSS, ELISA, recommend both tests,
2002
Abou Eisha, A.M.; El Attar,
A.A.; El Sheary, M.N. Bovine and atypical mycobacterial
infections of cattle and buffaloes in Port Said Province, Egypt. Assiut Veterinary Medical Journal. 2002. 47 (93) 152-162.
NAL Call Number: SF604 A77
Descriptors: Bubalus, disease incidence, epidemiology,
lymph nodes, tuberculin, tuberculosis, buffalo, cattle, Mycobacterium avium
complex, Mycobacterium bovis, Mycobacterium
fortuitum, Mycobacterium kansasii,
Mycobacterium smegmatis,
Adhikary, M.K.; Mondal, M.; Basak, D.K. Pulmonary
tuberculosis in cattle -- a study on its incidence and pathology.
Journal of Interacademicia. 2002, 6 (Special issue) 694-699.
Descriptors: adult cattle, post-slaughter tissue sampling, lungs, lesions described,
disease incidence levels, histopathological examinations, tubercles, epidemiology,
Amadori, M.;
Lyashchenko, K.P.; Gennaro, M.L.;
Pollock, J.M.; Zerbini, I. Use
of recombinant proteins in antibody tests for bovine tuberculosis. Veterinary Microbiology. Apr 2,
2002.
85 (4) 379-389. ISSN: 0378-1135
NAL Call Number: SF601.V44
Abstract: Tuberculosis (TB) in cattle remains a major zoonotic and economic problem in many countries. Since the
standard diagnostic assay, the intradermal test
(IDT) with bovine PPD tuberculin, has less than optimal
accuracy in all situations, other diagnostic methods such as serological assays
have been investigated. Because of fundamental concerns for the low sensitivity
and specificity of previous ELISA protocols, a profiling ELISA with nine purified,
recombinant proteins of TB complex mycobacteria,
was employed on samples from four groups of cattle: (a) naturally Mycobacterium
avium-exposed and experimentally Mycobacterium
bovis-infected, (b) officially-certified TB-free herds,
(c) exposed to M. bovis in two field TB outbreaks
and scored as bovine reactors in the gamma-IFN assay for bovine TB, (d) paratuberculosis
(para TB)-infected. The described ELISA proved to be highly
specific. In fact, the antibody (Ab) response could
be consistently detected in 3 out of 3 endotracheally-infected
calves and in 1 out of 3 contact-infected calves. There was also a very low
prevalence of low-titered, non-specific Ab responses in paraTB-infected
animals. As for the animals exposed to field TB outbreaks, 16 out of 28 gamma-IFN
positive cattle were also Ab-positive; importantly,
7 out of 12 gamma-IFN positive, IDT negative cattle showed Ab responses to TB proteins. In general, the profile of the
Ab response varied among animals; the reaction to
single recombinant antigens was sometimes transient and fluctuating, whereas
the panel of antigens on the whole was indeed more effective in Ab detection.
Descriptors: cattle tuberculosis antibodies, diagnostic techniques,
recombinant proteins, tuberculin, serology, ELISA, Mycobacterium avium,
Mycobacterium bovis, outbreaks, interferon,
Mycobacterium paratuberculosis, detection.
Amadori, M.; Tagliabue,
S.; Lauzi, S.; Finazzi,
G.; Lombardi, G.; Telo, P.; Pacciarini,
L.; Bonizzi, L. Diagnosis of Mycobacterium
bovis infection in calves sensitized by mycobacteria
of the avium/intracellulare group. Journal
of Veterinary Medicine. Series B. 2002. 49 (2) 89-96.
NAL Call Number: 41.8 Z52
Descriptors: diagnosis, experimental infections, interferon,
tuberculin, cattle, calves, Mycobacterium avium
complex, Mycobacterium bovis, diagnostic
procedures.
Anonomyous. A
crisis in the making. Veterinary Record. July
13, 2002. 151 (2) 33. ISSN: 0042-4900
NAL Call Number: 41.8 V641
Descriptors: cattle, tuberculosis, disease control, testing,
Anonomyous. Keeping the lid on bovine TB.
Veterinary Record. Mar 2, 2002. 150
(9) 257. ISSN: 0042-4900
NAL Call Number: 41.8 V641
Descriptors: cattle tuberculosis, Mycobacterium bovis,
diagnosis, disease control.
Bengis, R.G.;
Kock, R.A.; Fischer, J. Infectious animal diseases: the wildlife/livestock interface. Revue Scientifique
et Technique Office International des Epizooties.
2002. 21 (1) 53-65. Note: In English with Spanish and French summaries.
NAL Call Number: SF781 R4
Descriptors: analytical methods, animal diseases, brucellosis,
Brucella, diagnosis, diagnostic techniques,
disease control, ecotourism, livestock, rinderpest,
tuberculosis, wildlife conservation.
Buddle,
B.M.; Wards, B.J.; Aldwell, F.E.; Collins, D.M.;
de Lisle, G.W. Influence of sensitization to environmental mycobacteria
on subsequent vaccination against bovine tuberculosis. Vaccine.
2002. 20 (7-8) 1126-1133.
NAL Call Number: QR189 V32
Descriptors: BCG vaccine, calves, cattle, humans, immune response,
immunization, interferon, interleukin-2, live vaccines, potency, efficacy,
tuberculosis, vaccination, virulence, Mycobacterium bovis,
Mycobacterium avium, purified protein derivative, sensitization.
Buddle,
B.M.; Skinner, M.A.; Wedlock, D.N.; Collins, D.M.; de Lisle, G.W.; Fossum, C. (ed.); Wattrang, E.
New generation vaccines and delivery systems for control
of bovine tuberculosis in cattle and wildlife. Veterinary
Immunology and Immunopathology. 2002. 87 (3-4) 177-185. ISSN:
0165-2427. Note: 6th International Veterinary Immunology Symposium, Ultuna Campus, Swedish University of Agricultural Sciences, Uppsala,
NAL Call Number: SF757.2.V38
Descriptors: vaccines, Mycobacterium bovis,
cattle, wildlife.
Cataldi, A.A.; Gioffre,
A.; Santtangelo, M.P.; Alito,
A.; Caimi, K.; Bigi, F.;
Romano, M.I.; Zumarraga, M. El genotipo
de Mycobacterium bovis mayoritario
en la Argentina lo es tambien
en las Islas Britanicas: la tuberculosis bovina provino
de Gran Bretana? [The
prevailing genotype of Mycobacterium bovis in
Descriptors: cattle, Mycobacterium bovis,
epidemiology, genotypes, imported infections,
Choi, K.P.;
Kendrick, N.; Daniels, L. Demonstration that fbiC
is required by Mycobacterium bovis BCG for coenzyme F420 and FO biosynthesis. Journal
of Bacteriology. 2002, 184 (9) 2420-2428. ISSN: 0021-9193
NAL Call Number: 448.3 J82
Descriptors: amino acid sequences, coenzyme F420 and FO biosynthesis, coenzymes, genes, histidine, mutants, proteins, Mycobacterium bovis
BCG, antituberculosis drug PA-824.
Cobner, A.J.
Electronic submission of tuberculosis test data.
Cattle Practice. 2002. 10 (4) 231-233.
NAL Call Number: SF961 C37
Descriptors: accuracy, data analysis, data collection and processing,
recording, tests, tuberculosis, cattle, Mycobacterium bovis.
Cockle,
P.J.; Gordon, S.V.; Lalvani, A.; Buddle, B.M.; Hewinson, R.G.; Vordermeier, H.M.
Identification of novel Mycobacterium tuberculosis antigens with potential
as diagnostic reagents or subunit vaccine candidates by comparative genomics.
Infection and Immunity. 2002, 70 (12) 6996-7003.
ISSN: 0019-9567
NAL Call Number: QR1.I57
Descriptors:
cattle, Mycobacterium bovis, Mycobacterium tuberculosis,
bacterial antigens, diagnostic antigens, genes, immunization, molecular genetics,
tuberculin, vaccination, vaccine development, vaccines.
Collins,
J.D. The control of tuberculosis in cattle: an Irish view. Cattle
Practice. 2002. 10 (4) 223-229.
NAL Call Number: SF961 C37
Descriptors: assays, detection, diagnosis, disease control,
geographical information systems, risk, tests, tuberculin, tuberculosis, cattle,
Mycobacterium bovis, Irish Republic.
Constant,
P.; Perez, E.; Malaga, W.; Laneelle, M.A.; Saurel, O.; Daffe, M.; Guilhot, C. Role of the pks15/1 gene in the biosynthesis
of phenolglycolipids in the Mycobacterium tuberculosis
complex: evidence that all strains synthesize glycosylated
p-hydroxybenzoic methyl esters and that strains
devoid of phenolglycolipids harbor a frameshift mutation in the pks15/1 gene. Journal of Biological Chemistry. 2002. 277 (41) 38148-38158.
NAL Call Number: 381 J824
Descriptors: biosynthesis, genes, glycolipids,
phenolic acids, tuberculosis, virulence, phthiocerol, Mycobacterium tuberculosis, phenolphthiocerol.
Cooksey,
R.C.; Morlock, G.P.; Holloway, B.P.; Limor, J.; Hepburn, M. Temperature-mediated heteroduplex
analysis performed by using denaturing high-performance liquid chromatography
to identify sequence polymorphisms in Mycobacterium tuberculosis complex
organisms. Journal of Clinical Microbiology.
2002. 40 (5) 1610-1616.
NAL Call Number: QR46.J6
Descriptors: antituberculous agents, drug resistance,
ethambutol, genes, genetic polymorphism, HPLC, isoniazid,
methodology, mutations, nucleotide sequences, pyrazinamide,
rifampicin, streptomycin, Mycobacterium tuberculosis.
Costantini, F. Aspetti
igienico-sanitari degli
allevamenti di ungulati selvatici: malattie infettive e monitoraggio sanitario. [Hygiene and health aspects affecting the breeding of wild ungulates.
Infectious diseases and the monitoring of health.]
Notiziario ERSA. 2002, 15 (4) 21-25.
Note: In Italian.
Descriptors:
captive wild ungulates, health monitoring, African swine fever virus,
Aphthovirus, Bluetongue virus, anthrax, brucellosis,
enteritis, legislation, pleuropneumonia, Mycobacterium,
tuberculosis, wild animals,
Cvetnic, Z.;
Zeman, M.; Spicic, S.; Majnaric, D.; Bukovic-Sosic, B.;
Mitak, M. Epizootija tuberkuloze goveda
u seoskom gospodarstvu. [Epidemiology of
tuberculosis in cattle in a rural husbandry.] Veterinarska
Stanica. 2002. 33 (1) 23-30. Note: In Croatian
with an English summary.
Descriptors: cattle, clinical aspects,
cows, disease prevalence, epidemiology, tuberculin, tuberculosis, Mycobacterium
bovis, pigs, post-slaughter,
Dandapat, P.; Rishendra,Verma;
Venkatesan, K.; Sharma, V.D.; Katoch,
V.M.; Verma, R. Identification
of the bound and unbound lipids on the cell envelopes of Mycobacterium
bovis. Indian
Journal of Animal Sciences. 2002, 72 (11) 946-950. ISSN: 0367-8318
NAL Call Number: 41.8 IN22
Descriptors:
16 isolates, bovine tissue derivation, Mycobacterium tuberculosis,
Mycobacterium bovis BCG, Mycobacterium
avium, C-mycosides,
phosphytidyl inositol mannosides, polar glycolipids, bacterial antigens, envelope glycoproteins.
Dargatz, D.A.;
Garry, F.B.; Traub-Dargatz. J.L.
An introduction to biosecurity of cattle operations. Veterinary Clinics of North America, Food Animal Practice. 2002. 18 (1) 1-5.
NAL Call Number: SF601 V535
Descriptors: etiology, animal health, brucellosis, cattle diseases,
cattle farming, disease prevention, foot and mouth disease, FMD, Mycobacterium
tuberculosis, biosecurity.
Delafosse, A.;
Goutard, F.; Thebaud, E. Epidemiologie
de la tuberculose et de
la brucellose des bovins en zone periurbaine d'Abeche, Tchad. [Epidemiology of bovine tuberculosis and brucellosis on the periphery
of Abeche,
NAL Call Number: 41.8 R3262
Descriptors: dairy cattle, bovine brucellosis and tuberculosis, age groupings, brucellosis, disease prevalence and control, disease transmission,
epidemiology, herd risk factors, Mycobacterium avium,
Mycobacterium bovis, Chad.
Doherty, M.L.; Cassidy, J.P. New perspectives on bovine tuberculosis.
Veterinary Journal. Mar 2002. 163 (2) 109-110.
ISSN: 1090-0233
NAL Call Number: SF601.V484
Descriptors: cattle, Mycobacterium bovis,
tuberculosis, disease control.
Freitas, J. de A.; Panetta, J.C. Some epidemiological aspects of tuberculosis in water buffaloes in the Amazon
Descriptors: water buffalo, slaughter animal survey for diseases, Mycobacterium bovis, gender differences, climate effects, nutritional value, age, disease transmission,
Frolich, K.; Thiede, S.; Kozikowski, T.; Jakob, W. A review of mutual transmission of important infectious diseases between livestock and wildlife in
Descriptors: wild red foxes, oral vaccination against rabies, zoonotic disease such as hog cholera in wild boar and domestic pigs, cattle and roe deer get BVD, myxomatosis and rabbit hemorrhagic disease in rabbits, Mycobacterium bovis in cattle, wild boars, badgers, deer, viral diseases, bacterial disease, serological surveys, various European countries.
Garcia
de Viedma, D.; del S. Diaz Infantes, M.; Lasala, F.; Chaves,
F.; Alcala, L.; Bouza,
E.; del S. Diaz Infantes, M. New real-time PCR able to
detect in a single tube multiple rifampin resistance mutations and high-level isoniazid resistance mutations in Mycobacterium tuberculosis. Journal of Clinical Microbiology. 2002.
40 (3) 988-995.
NAL Call Number: QR46.J6
Descriptors: antituberculous agents, drug resistance,
isoniazid, mutations, polymerase chain reaction,
rifampicin, strains, Mycobacterium tuberculosis.
Garnett,
B.T.; Delahay, R.J.; Roper, T.J. Use of cattle
farm resources by badgers (Meles meles)
and risk of bovine tuberculosis (Mycobacterium bovis)
transmission to cattle. Proceedings
of the Royal Society of London.
Series B, Biological Sciences. July 22, 2002.
269 (1499) 1487-1491. ISSN: 0962-8452
NAL Call Number: 501 L84B
Descriptors: cattle, badgers, Meles meles, disease
transmission, cattle housing, feeds, contamination, Mycobacterium bovis.
Hancox, M. The great badgers and
bovine TB debate. Journal of Agricultural Science. 2002, 139 (2) 223-226.
ISSN: 0021-8596
NAL Call Number: 10 J822
Descriptors:
badgers, cattle, wildlife disease reservoir, disease control program, public
health risks, risk assessment, tuberculosis, Mycobacterium
tuberculosis, zoonoses.
Hasegawa,
N.; Miura, T.; Ishii, K.; Yamaguchi, K.; Lindner, T.H.; Merritt, S.; Matthews,
J.D.; Siddiqi, S.H. New simple and rapid test
for culture confirmation of Mycobacterium tuberculosis complex: a multicenter study. Journal of Clinical
Microbiology. 2002, 40 (3) 908-912.
NAL Call Number: QR46.J6
Descriptors: antigens, bacterial growth, rapid diagnostic methods,
Mycobacterium bovis, Mycobacterium tuberculosis complex, Mycobacterium
africanum, MPB64 antigen, sensitivity, specificity.
Hauser, R.; Hadorn, D.;
Rufenacht, J.; Stark, K. Examens
par sondages permettant
d'etablir que la Suisse est indemne
de certaines epizooties. Nouvelle
methode. [Documentation on the free-of-disease situation with active surveillance
in
Descriptors: disease eradication, brucellosis, tuberculosisi, IBR, EBL, active surveillance, data gathering,
sampling, simulation model, animal health, Aujeszky’s
disease, risk-based approach, Mycobacterium tuberculosis, pigs, Switzerland.
Jackson, R. Veterinary epidemiology
in
NAL Call Number: 41.8 N483
Descriptors: animal diseases, computer software, epidemiology,
pets, tuberculosis, cattle, pigs
Kaneene, J.B.; Bruning-Fann,
C.S.; Granger, L.M.; Miller, R.; Porter-Spalding, B.A. Environmental and
farm management factors associated with tuberculosis on cattle farms in northeastern
Michigan. Journal of the American Veterinary
Medical Association. Sept
15, 2002.
221 (6) 837-842. ISSN: 0003-1488
NAL Call Number: 41.8 AM3
Descriptors: cattle, farms, tuberculosis, Mycobacterium bovis,
farm management, environmental factors, risk factors, wild animals, disease
prevalence, livestock numbers, ponds, streams, Michigan.
Kaneene, J.B.; VanderKlok,
M.; Bruning-Fann, C.S.; Palmer, M.V.; Whipple, D.L.;
Schmitt, S.M.; Miller, R.A. Prevalence of Mycobacterium bovis
infection in cervids on privately owned ranches.
Journal of the American Veterinary Medical Association.
2002. 220 (5) 656-659. ISSN: 0003-1488
NAL Call Number: 41.8 AM3
Descriptors: analytical methods, diagnosis, diagnostic techniques,
disease prevalence, epidemiology, tuberculosis, Cervidae,
coyotes, deer, tuberculosis, Mycobacterium bovis,
wildlife, slaughter and skin testing, disease transmission, Michigan.
Kennedy,
H.E.; Welsh, M.D.; Bryson, D.G.; Cassidy, J.P.; Forster, F.I.; Howard, C.J.;
Collins, R.A.; Pollock, J.M. Modulation of immune responses to Mycobacterium
bovis in cattle depleted of WC1+ gammadelta
T cells. Infection and Immunity.
Mar 2002. 70 (3) 1488-1500. ISSN: 0019-9567
NAL Call Number: QR1.I57
Abstract: It is accepted that cell-mediated immune responses
predominate in mycobacterial infections. Many studies
have shown that CD4(+) T cells produce Th1 cytokines,
such as gamma interferon (IFN-gamma), in response to mycobacterial antigens and that the cytolytic
activity of CD8(+) cells toward infected macrophages is important. However,
the extent and manner in which gammadelta T cells
participate in this response remain unclear. In ruminants, gammadelta
T cells comprise a major proportion of the peripheral blood mononuclear cell
population. We have previously shown that WC1(+)
gammadelta T cells are involved early in Mycobacterium
bovis infection of cattle, but their specific
functions are not well understood. Here we describe an in vivo model of bovine
tuberculosis in which the WC1(+) gammadelta T cells were depleted
from the peripheral circulation and respiratory tract, by infusion of WC1(+)-specific
monoclonal antibody, prior to infection. While no effects on disease pathology
were observed in this experiment, results indicate that WC1(+) gammadelta
T cells, which become significantly activated (CD25(+)) in the circulation
of control calves from 21 days postinfection, may play a role in modulating the developing
immune response to M. bovis. WC1(+)-depleted
animals exhibited decreased antigen-specific lymphocyte proliferative
response, an increased antigen-specific production of interleukin-4, and a
lack of specific immunoglobulin G2 antibody. This suggests that WC1(+) gammadelta TCR(+) cells contribute, either directly or indirectly,
toward the Th1 bias of the immune response in bovine tuberculosis--a hypothesis
supported by the decreased innate production of IFN-gamma, which was observed
in WC1(+)-depleted calves.
Descriptors: T lymphocytes, lymphocyte transformation, cell
mediated responses, calves, tuberculosis, Mycobacterium
bovis.
Kim,
J.H.; Sohn, H.J.; Kang, K.I.; Kim, W.I.; An, J.S.;
Jean, Y.H. Mycobacterium bovis infection
in a farmed elk in Korea. Journal of Veterinary Science. Sept 2002. 3 (3) 163-166. ISSN:
1229-845X
URL:
http://www.ksvs.or.kr
NAL Call Number: SF604.J68
Descriptors: Cervus
elaphus, game farming, animal diseases, Mycobacterium bovis,
tuberculosis, case reports, postmortem examinations, lungs, lymph nodes, histopathology,
abscesses, granuloma, Korea Republic.
Krayc, B. (ed) ; Schonthaler, D. Tagungsbericht
1. Fachtagung fur Ziegenzuchter
und halter zum Thema Ziegenzucht und Ziegenhaltung, 12.
November und 13. November 2002,
BAL Gumpenstein, Irdning,
Descriptors:
breeding, EU, nutritional value of goat products, goats milk, grazing in alpine
areas, feeding, Tauern Pied, tuberculosis, mastitis,
Johne’s disease, brucellosis, etc.
Kwong, L.S.; Hope, J.C.; Thom, M.L.; Sopp, P.; Duggan, S.; Bembridge, G.P.; Howard, C.J. Development of an ELISA for bovine IL-10. Veterinary Immunology and Immunopathology. 2002; 85 (3/4): 213-223. ISSN: 0165-2427
URL: http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number: SF757.2.V38
Abstract: The objective of the study was to develop an assay for bovine IL-10 that could be applied to analyses of immune responses and advance understanding of a variety of diseases of cattle. Recombinant bovine IL-10 (rbo IL-10) was transiently expressed in Cos-7 cells and shown to inhibit the synthesis of IFNgamma by bovine cells stimulated with antigen in vitro. Mice were immunised with a plasmid containing a cDNA insert encoding rbo IL-10 and inoculated with rbo IL-10. A number of monoclonal antibodies (mab) were generated that reacted with rbo IL-10 in an ELISA. Some of these mab neutralised the ability of rbo IL-10 to inhibit IFNgamma synthesis by antigen-stimulated bovine cells. A pair of mabs was identified that together could be used to detect both recombinant and natural bovine IL-10 present in supernatant of PBMC stimulated with ConA. A luminescent detection method was applied to the ELISA making it more sensitive. Using this method native IL-10 was detected in supernatants of PBMC, diluted blood and undiluted blood from cattle immunised with Mycobacterium bovis BCG or ovalbumin and incubated in vitro with antigen indicating the applicability of the assay to a number of in vitro culture systems.
Descriptors: cattle, interleukin 10, ELISA, monoclonal antibodies, interferon, recombinant DNA, complementary DNA, protein synthesis, inhibition.
Lis, H.
Wyniki badania sanitarno-weterynaryjnego zwierzat
rzeznych i miesa w Polsce w 2000 r. [Results
of veterinary inspection of slaughtered animals and meat in
NAL Call Number: 41.8 M463
Descriptors: calves, carcasses, cysticercosis,
diagnosis, echinococcosis, emaciation, food safety,
jaundice, lesions, leukemia, liver flukes, meat, meat inspection, neoplasms, septicaemia, slaughter,
trichinosis, tuberculosis, horses, Mycobacterium tuberculosis, pigs,
sheep, Trichinella, Poland.
Livingstone, P.; McInnes,
J.; Carter, C.; Ryan, T.; Hancox, N. Controlling bovine tuberculosis in cattle where there is
a wildlife source of infection. Bulletin
of the International Dairy Federation. 2002. No. 372, 33-42. Note:
A fresh perspective for managing milk-borne diseases. Proceedings
of the Animal Health Conference, IDF World Dairy Summit 2001, Auckland,