Livestock

 

2007

Alsop, E.J.; Marr, C.; Barrelet, A.B.; McGladdery, A.J.  The use of transabdominal ultrasonography in the diagnosis and management of splenic lesions in three horses.   Equine Veterinary Education.  2007; 19 (1): 5-10.  ISSN:  0957-7734
URL:   http://www.evj.co.uk
NAL Call Number:  SF951.E67
Descriptors:  horses, splenic lesions, clinical picture, Mycobacterium avium.

Benet, J.J.; Boschiroli, M.L.; Dufour, B.; Garin-Bastuji, B.  Lutte contre la tuberculose bovine en France de 1954 a 2004: analyse de la pertinence epidemiologique de l'evolution de la reglementation.  [Bovine tuberculosis control programme in France from 1954 to 2004: epidemiological relevance analysis of regulations texts.]  Epidemiologie et Sante Animale.  2006; (50): 127-143.  ISSN:  0754-2186.  Note:  In French with an English summary.  
Descriptors:  Mycobacterium bovis, collective control program, disease free in 2001, epidemiology, description of regulations and management, France.

Bennett, R.; Willis, K.  Public opinions on badger populations and the control of tuberculosis in cattle in the UKVeterinary Record.  2007; 160 (8): 266-268.  ISSN:  0042-4900
URL:  http://veterinaryrecord.bvapublications.com/archive/
NAL Call Number:  41.8 V641
Descriptors:  opinion survey questionnaire, prevention of bovine tuberculosis, badger management, telephone and mail survey, wildlife management sometimes necessary, role of government, opinions of population management of badgers, cost/benefit, England, Wales.

Cvetnic, Z.; Spicic, S.; Benic, M.; Katalinic-Jankovic, V.; Pate, M.; Krt, B.; Ocepek, M.  Mycobacterial infection of pigs in CroatiaActa Veterinaria Hungarica.  2007; 55 (1): 1-9.  ISSN:  0236-6290
URL:  www.akademiai.com
NAL Call Number:  41.8 AC83
Descriptors:  pigs, bacterial infections, bacterioses, disease surveillance, Mycobacterium peregrinum, lymph nodes, Croatia.

Flynn, Robin J.; Mannion, Celine; Golden, Olwen; Hacariz, Orcun; Mulcahy, Grace.  Experimental Fasciola hepatica infection alters responses to tests used for diagnosis of  bovine tuberculosis.  Infection and Immunity (IAI).  2007 Mar; 75 (3): 1373-1381.  ISSN:  0019-9567
URL:  http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  Fasciola hepatica is a prevalent helminth parasite of livestock. Infection results in polarization of the host's immune response and generation of type 2 helper (Th2) immune responses, which are known to be inhibitory to Th1 responses.  Bovine tuberculosis (BTB) is a bacterial disease of economic and zoonotic importance.  Control polices for this disease rely on extensive annual testing and a test-and-slaughter policy.  The correct diagnosis of BTB relies on cell-mediated immune responses.  We established a model of coinfection of F. hepatica and Mycobacterium bovis BCG to examine the impact of helminth infection on correct diagnosis.  We found the predictive capacity of tests to be compromised in coinfected animals and that F. hepatica infection altered macrophage function.  Interleukin-4 and gamma interferon expression in whole-blood lymphocytes restimulated in vitro with M. bovis antigen was also altered in coinfected animals.  These results raise the question of whether F. hepatica infection can affect the predictive capacity of tests for the diagnosis of BTB and possibly also influence susceptibility to BTB and other bacterial diseases.  Further studies on the interplay between helminth infection and BTB are warranted.  
Descriptors:  livestock, Fasciola hepatica, liver fluke, Mycobacterium bovis BCG, co-infection of helminths and bacteria, question whether bovine tuberculosis testing compromised, suggest further studies.

Foote, M.R.; Nonnecke, B.J.; Beitz, D.C.; Waters, W.R.  High growth rate fails to enhance adaptive immune responses of neonatal calves and is associated with reduced lymphocyte viability.  Journal of Dairy Science.  2007; 90 (1): 404-417.  ISSN:  0022-0302
URL:  http://jds.fass.org/cgi/content/full/90/1/404
NAL Call Number:  44.8 J822
Abstract:  The objective of the study was to evaluate the effects of 3 targeted growth rates on adaptive (i.e., antigen-specific) immune responses of preruminant, milk replacer-fed calves.  Calves (9.1 +/- 2.4 d of age) were assigned randomly to one of 3 dietary treatments to achieve 3 targeted daily rates of gain [no growth (maintenance) = 0.0 kg/d, low growth = 0.55 kg/d, or high growth = 1.2 kg/d] over an 8-wk period.  The NRC Nutrient Requirements of Dairy Cattle calf model computer program was used to estimate the milk replacer intakes needed to achieve target growth rates.  All calves were fed a 30% crude protein, 20% fat, all-milk protein milk replacer reconstituted to 14% dry matter. Diets were formulated to ensure that protein would not be limiting.  All calves were vaccinated 3 wk after initiation of dietary treatments with Mycobacterium bovis, strain bacillus Calmette-Guerin and ovalbumin.  Growth rates for no-growth (0.11 kg/d), low-growth (0.58 kg/d), and high-growth (1.16 kg/d) calves differed throughout the experimental period.  Blood glucose concentrations in high-growth calves increased with time and were higher than in low- and no-growth calves.  Mononuclear and polymorphonuclear leukocyte percentages in peripheral blood were unaffected by growth rate but did change with advancing age.  Percentages of CD4(+) T cells increased with age in no-growth and low-growth calves, a characteristic of maturation, but failed to increase in high-growth calves.  Growth rate did not affect the percentages of CD45RO(+) (memory) CD4(+) and CD8(+) T cells, antigen (i.e., ovalbumin)-specific serum IgG concentrations, or antigen (i.e., purified protein derivative)-induced IFN-gamma and nitric oxide secretion by mononuclear cell cultures.  Antigen-elicited cutaneous delayed-type hypersensitivity responses of no-growth calves exceeded responses of low-growth, but not high-growth, calves.  In resting- and antigen-stimulated cell cultures, viabilities of CD4(+), CD8(+), and gamma delta TCR+ T cells from high-growth calves were lower than those of the same T cell subsets from no-growth and low-growth calves.  Alternatively, resting cultures of mononuclear leukocytes from high-growth calves produced more nitric oxide than those from no-growth and low-growth calves. In conclusion, adaptive immune responses were affected minimally by growth rate.  The results suggest that protein-energy malnutrition in the absence of weight loss is not detrimental to antigen-specific responses of neonatal vaccinated calves and that a high growth rate does not enhance these responses.  The negative effect of a high growth rate on the viability of circulating T cell populations may influence infectious disease resistance of the calf.
Descriptors:  neonates, cattle disease, Mycobacterium bovis, serum, immune system, CD8+ T-cell, CD4+ T cell, adaptive immunity, growth rates.

Gumussoy, vK.S.; Atasever, A.; Aydn, F.; Ozcan, M.; Beyaz, L.; Hzlsoy, H.; Abay, S.  Prevalence of tuberculosis in cattle in Turkey.  Medycyna Weterynaryjna.  2007; 63 (3): 305-308.  ISSN:  0025-8628.  Note:  In English with a Polish summary.  
NAL Call Number:  41.8 M463
Descriptors:  cattle, disease prevalence, bovine tuberculosis, Mycobacterium bovis, tissues from slaughtered cattle, 5 abattoirs, lungs, bronchi, mediastinal lymph nodes, BACTEC radiometric method was a rapid and sensitive diagnostic method, Kayseri province, Turkey.

Johnson, L.; Dean, G.; Rhodes, S.; Hewinson, G.; Vordermeier, M.; Wangoo, A.  Low-dose Mycobacterium bovis infection in cattle results in pathology indistinguishable from that of high-dose infection.  Tuberculosis.  2007; 87 (1): 71-76.  ISSN:  1472-9792
URL:  http://www.sciencedirect.com/science/journal/14729792
Descriptors:  cattle, experimental infection, Mycobacterium bovis field strain (AF2122/97) effects of low and high doses of colony forming units, immunohistochemistry, lesion advancement and granuloma distribution, IFN gamma expression, 24 week study, no difference in infection between high and low dosages.

Jolley, M.E.; Nasir, M.S.; Surujballi, O.P.; Romanowska, A.; Renteria, T.B.; Mora, A. de la; Lim, A.; Bolin, S.R.; Michel, A.L.; Kostovic, M.; Corrigan, E.C.  Fluorescence polarization assay for the detection of antibodies to Mycobacterium bovis in bovine sera.  Veterinary Microbiology.  2007; 120 (1/2): 113-121.  ISSN:  0378-1135
URL:   http://www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  The performance of a fluorescence polarization assay (FPA) that detects antibodies to Mycobacterium bovis in bovine sera is described.  The FPA reported here is a direct binding primary screening assay using a small polypeptide derived from the M. bovis MPB70 protein.  A secondary inhibition assay confirms suspect or presumed positive samples.  Specificity studies involved five different veterinary laboratories testing 4461 presumed negative bovine samples.  FPA specificity was 99.9%.  The FPA was used to identify herd status as either M. bovis infected or non-infected.  Herd surveillance studies (nine herds) were performed in Mexico and South Africa.  The FPA had a specificity of 100% (two negative herds), and correctly identified six of seven infected herds.  Finally, sera from 105 slaughter animals that had gross lesions in lymph nodes similar to those seen with bovine tuberculosis were tested by the FPA.  Thin sections from the associated formalin-fixed paraffin-embedded samples of lymph nodes were stained using hematoxylin and eosin (H&E) for morphologic examination and using the Ziehl-Neelsen (ZN) method for detection of acid-fast bacilli.  Of the 105 animals, 78 were classified as TB suspect based on lesion morphology, 21 were positive by ZN, 9 were positive by FPA and 13 were positive by PCR for the tuberculosis group of Mycobacterium.  Among the 21 ZN positives, 11 (52.4%) were PCR positive. Among the 9 FPA positives, 8 (88.9%) were PCR positive.  For the 13 PCR positives, 8 (61.5%) were FPA positive and 11 (84.6%) were ZN positives.  These results show that use of the FPA for detection of M. bovis infection of cattle has value for bovine disease surveillance programs.
Descriptors:  cattle, Mycobacterium bovis, disease surveillance, serological diagnosis, serological techniques, Mexico, South Africa.

Komijn, R.E.; Wisselink, H.J.; Rijsman, V.M.C.; Stockhofe-Zurwieden, N.; Bakker, D.; Zijderveld, F.G. van; Eger, T.; Wagenaar, J.A.; Putirulan, F.F.; Urlings, B.A.  Granulomatous lesions in lymph nodes of slaughter pigs bacteriologically negative for Mycobacterium avium subsp. avium and positive for Rhodococcus equi.  Veterinary Microbiology.  2007; 120 (3/4): 352-357.  ISSN:  0378-1135
URL:  http://www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  The prevalence of granulomatous lesions in lymph nodes of pigs was studied.  From January till August 2004 in two slaughterhouses in The Netherlands 2 116 536 pigs were examined for the presence of granulomatous lesions in the sub-maxillary lymph nodes.  In 15 900 (0.75%) of these pigs, lesions could be detected.  Nine farms with the highest incidence of lesions were selected for a more detailed pathological and bacteriological examination.  On these farms, the prevalence of lesions in sub-maxillary lymph nodes ranged from 2.3 to 5.7% with a mean of 3.0%.  From 1276 pigs that were sampled, 98 (7.7%) displayed granulomatous lesions in the sub-maxillary lymph nodes and one (0.1%) pig showed lesions in its mesenteric lymph node.  Mycobacterium avium subsp. avium (MAA) could not be isolated from the lymph nodes of the 99 pigs with lesions and from a selection of lymph nodes (n=61) of pigs without lesions.  Rhodococcus equi was isolated from 44 out of 98 (44.9%) of the sub-maxillary lymph nodes with granulomatous lesions and from two mesenteric lymph nodes without lesions.  A comparison of former studies and the current results indicate that the prevalence of MAA infections in slaughter pigs has strongly decreased over the last decade, whereas R. equi is highly prevalent.  The high incidence of granulomatous lesions associated with the bacteriological presence of R. equi could be considered as a serious cause of misdiagnosis of MAA infections in cases where meat inspection is carried out by inspection for granulomatous changes of lymph nodes only..
Descriptors:  pigs, Mycobacterium avium, Rhodococcus equi, disease surveillance, slaughter house survey, The Netherlands.  

Liu, Siguo; Guo, She Ping; Wang, Chun Lai; Shao, Mei Li; Zhang, Xiu Hua; Guo, Yang; Gong, Qiang.  A novel fusion protein-based indirect enzyme-linked immunosorbent assay for the detection of bovine tuberculosisTuberculosis (Amsterdam).  2007; 87 (3): 212-217.  ISSN:  1472-9792
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/638428/description?navopenmenu=-2

Descriptors:  ELISA; serodiagnosis of Mycobacterium bovis; antigen genes, mpb70, mpb83, and esat-6; spliced overlap extension technology; expressed in Escherichia coli; fusion protein (rM7083-E6); serum testing of cattle; sensitivity and specificity.

Marsh, I.B.; Whittington, R.J.  Genomic diversity in Mycobacterium avium: Single nucleotide polymorphisms between the S and C strains of M-avium subsp paratuberculosis and with M-a. aviumMolecular and Cellular Probes.  2007; 21 (1): 66-75.  ISSN:  0890-8508
URL:  http://www.sciencedirect.com/science/journal/08908508
Descriptors:  sheep; cattle; Mycobacterium avium paratuberculosis; strain C; strain S; Mycobacterium avium avium; amino acid sequence; nucleotide sequence; genomic diversity; species comparison; GenBank sequence numbers; 12,117 bp of sequence representing 26 loci across 25 genes; 11 SNPs were identified between the S and C strains in eight genes: hsp65, sodA, dnaA, dnaN, recF, gyrB, inhA, and pks8.

Meikle, V.; Schneider, M.; Azenzo, G.; Zumarraga, M.; Magnano, G.; Cataldi, A.  Individual animals of a cattle herd infected with the same Mycobacterium bovis genotype shows important variations in bacteriological, histopathological and immune response parameters.  Zoonoses and Public Health.  2007; 54 (2): 86-93.  ISSN:  1863-1959
Descriptors:  Friesian cattle, Mycobacterium bovis, tuberculin test, slaughterhouse surveillance, diagnostic tests comparison study, interferon gamma, PCR, bacteriological culture of nasal swab and intradermal tuberculin test, clinical parameter, tuberculosis lesions, spoligotyping, several tests recommended.

Montgomery, A.  Incidence and sensitivity of major bovine respiratory disease pathogens in Europe.  Veterinary Times.  2007; 37 (2): 24.  ISSN: 1352-9374
Descriptors:  cattle, acute signs of bovine respiratory disease, sampling with swabs, 220 pathogens isolated, Arcanobacterium pyogenes, Histophilus, Mycobacterium bovis, Pasteurella haemolytica, Pasteurella multocida, sensitivity to antiobiotics, florfenicol, tilmicosin, tulathromycin, tetracycline, 8 European countries.

Mores, Nelson; Ventura, Lauren; Dutra, Valeria; Silva, Virginia S.; Barioni, Waldomiro Jr; Oliveira, Salete R.; Kramer, Beatris.; Neto, Jose S. Ferreira.  Granulomatous lymphadenitis in swine: lymph nodes affected and pathologic diagnosis of the infection caused by Mycobacterium avium complex agents.  Pesquisa Veterinaria Brasileira.  2007; 27 (1): 13-17.  ISSN:  0100-736X.  Note:  In Portuguese.
NAL Call Number:  SF756.37.B7 P5
Descriptors:  394 swine carcasses from cold storage, Service of Federal Inspection, pigs, granulomatous lesions, lymph nodes, histopathology, Ziehl-Neelsen staining, histopathological examination, immunohistochemistry with monoclonal antibody produced with cellular extract of M. avium, comparison of tests, Brazil.

Mukherjee, F.  Comparative prevalence of tuberculosis in two dairy herds in India.  Revue Scientifique et Technique Office International des Epizooties.  2006; 25 (3): 1125-1130.  ISSN:  0253-1933.  Note:  In English with summaries in Spanish and French.  
Abstract:  Holstein Friesian cows and their crossbred progeny on a farm in northern India were tested for tuberculosis (TB) infection using a single intradermal tuberculin test.  The results showed that the animals persistently harboured TB infection for periods of two to four years.  The recent comparative intradermal tuberculin test revealed that at least five out of nine of these cattle reacted positively to bovine tuberculin purified protein derivative.  A high (15.76%) prevalence rate resulted because none of the infected animals had been segregated or culled from the herd since the first incidence was detected in 1992.  In contrast, another farm in western India that practiced segregation and culling was able to contain the level of prevalence of TB between 0.65% and 1.85%.  These findings call for stricter regulations on the management of TB at farm, state and country level and a revision in the mode of breeding programmes adopted by farms..
Descriptors:  cattle, disease control programs, effects of segregation and culling of TB infected cows, Mycobacterium bovis, India.

Ozygt, M.O.; Senturk, S.; Akkoc, A.  Suspected congenital generalised tuberculosis in a newborn calf.  Veterinary Record.  2007; 160 (9): 307-308.  ISSN:  0042-4900
URL:   http://veterinaryrecord.bvapublications.com/archive/
NAL Call Number:  41.8 V641
Descriptors:  cattle, newborn calf, Mycobacterium bovis, case report, clinical picture, postmortem examination, congenital disease, Turkey.

Porphyre, Thibaud; McKenzie, Joanna; Stevenson, Mark.  A descriptive spatial analysis of bovine tuberculosis in intensively controlled cattle farms in New ZealandVeterinary Research (Les-Ulis).  2007; 38 (3): 465-479.  ISSN:  0928-4249
URL:  http://www.vetres.org/
NAL Call Number: SF602.A5
Descriptors:  cattle, bovine tuberculosis, Mycobacterium bovis, 69 farms, poisoning for depopulating area of brushtail possum (Trichosurus vulpecula), wildlife disease reservoir, disease transmission from possums, North Island, New Zealand.

Raj, G.D.; Mathivanan, B.; Matheswaran, K.; Nachimuthu, K.; Davis, W.C.  Lymphocyte subset distribution in apparently normal and single intradermal test-positive water buffaloes analyzed by flow cytometry.  Research in Veterinary Science.  2007; 82 (1): 34-38. 
URL:  http://www.sciencedirect.com/science/journal/00345288
Descriptors:  water buffalo, lymphocytes, antibodies, CD3+ lymphocytes, CD8+ cells, histocompatibility complex, peripheral blood, T cells, T4 lymphocytes, mononuclear cells, single intradermal test, Mycobacterium bovis.

Seward, Nathan W.; Phillips, Gregory E.; Duquette, Jared F.; Vercauteren, Kurt C.  A frightening device for deterring deer use of cattle feeders.  Journal of Wildlife Management.  2007; 71 (1): 271-276.  ISSN:  0022-541X
URL:  http://www.bioone.org/perlserv/?request=get-archive&issn=0022-541X&ct=1
NAL Call Number:  410 J827
Abstract:  The presence of bovine tuberculosis (TB) in cattle can negatively impact a state's economy and cattle industry.  In Michigan, USA, wild white-tailed deer (Odocoileus virginianus) are a reservoir for reinfecting cattle herds.  Although direct TB transmission between deer and cattle is rare, infected deer may contaminate cattle feed.  To mitigate this risk, we designed and evaluated a deer-resistant cattle feeder (DRCF) device for deterring deer from feeders.  The device delivered negative stimuli to condition deer to avoid cattle feeders.  We tested the device by conducting a comparative change experiment at a high-density captive white-tailed deer operation in northeastern lower Michigan using pretreatment and treatment periods and random allocation of DRCF protection to 3 of 6 feeders during the treatment period.  We used animal-activated cameras to collect data on deer use of feeders.  Deer use was similar at protected and unprotected feeders during the pretreatment period but was lower at protected feeders during the treatment period.  Deer-resistant cattle feeders were 100% effective during the first 2 treatment weeks, 94% during the first 5 weeks, but effectiveness then dropped to 61% during the final week.  Excluding problems associated with low battery power and infrared sensors, DRCFs were 99% effective at deterring deer.  Our results suggest that DRCFs can effectively limit deer use of cattle feed, potentially with minimal impact on feeding behavior of cattle, thus reducing potential transmission of bovine TB through contaminated feed.  By employing DRCFs in bovine TB endemic areas, especially at times that deer are food stressed, agencies and producers can practically and economically reduce the potential for bovine TB to be transmitted from deer to cattle.
Descriptors:  white-tailed deer, (Odocoileus virginianus), feeding patterns, negative stimulus deer resistant cattle feeder, long term effectiveness, feeding stations, disease transmission between species, Mycobacterium bovis, wild vs captive deer operation, Michigan, US.

Smith, G.C.; Bennett, R.; Wilkinson, D.; Cooke, R.  A cost-benefit analysis of culling badgers to control bovine tuberculosis.  Veterinary Journal.  2007; 173 (2): 302-310.  ISSN:  1090-0233
URL:  http://www.sciencedirect.com/science/journal/10900233
Descriptors:  cattle, herds, badgers (Meles meles), simulated culling strategies, badger trapping and gassing, disease control strategy Mycobacterium bovis, disease transmission, UK Government's Department for Environment Food and Rural Affairs (Defra), UK.

Twomey, D.F.; Crawshaw, T.R.; Anscombe, J.E.; Farrant,.L.; Evans, L.J.; McElligott, W.S.; Higgins, R.J.; Dean, G.; Vordermeier, M.; Jahans, K.; Rua-Domenech, R. de la.  TB in llamas caused by Mycobacterium bovis.  Veterinary Record.  2007; 160 (5): 170.  ISSN:  0042-4900
URL:  http://veterinaryrecord.bvapublications.com/archive/
NAL Call Number:  41.8 V641
Descriptors:  llama herd, diagnosis of tuberculosis, Mycobacterium bovis, seroprevalence, tests for antibodies, intradermal tuberculin test, Devon, UK.

Vega-Manriquez, X.; Lopez-Vidal, Y.; Moran, J.; Adams, L.G.; Gutierrez-Pabello, J.A.  Apoptosis-inducing factor participation in bovine macrophage Mycobacterium bovis-induced caspase-independent cell death.  Infection and Immunity.  2007; 75 (3): 1223-1228.  ISSN:  0019-9567
URL:   http://iai.asm.org/
NAL Call Number:  QR1. I57
Abstract:  Mycobacterium tuberculosis complex species survive and replicate in phagosomes of the host cell.  Cell death (CD) has been highlighted as one of the probable outcomes in this host-pathogen interaction.  Previously, our group demonstrated macrophage apoptosis as a consequence of Mycobacterium bovis infection.  In this study, we aimed to identify the contribution of apoptotic effector elements in M. bovis-induced CD.  Bovine macrophages were either infected with M. bovis (multiplicity of infection, 10:1) or treated with an M. bovis cell extract (CFE).  Structural changes compatible with CD were evaluated.  Chromatin condensation was increased three times by the CFE.  On the other hand, a terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) assay demonstrated that levels of DNA fragmentation induced by M. bovis and CFE were 53.7%+or-24% and 38.9%+or-14%, respectively, whereas control cells had a basal proportion of 8.9%+or-4.1%.  Rates of DNA fragmentation were unaffected by the presence of the pan-caspase inhibitor N-benzyloxycarbonyl-Val-Ala-Asp (z-VAD).  Cells treated with 100 micro g of CFE for 12 h had a fivefold decrease in the level of mitochondrial outer membrane permeabilization compared to that of untreated cells.  Neither M. bovis infection nor CFE treatment induced activation of caspase 3, 8, or 9.  Translocation of apoptosis-inducing factor (AIF) to the nucleus was identified in 32%+or-3.5% and 26.3%+or-4.9% of M. bovis-infected and CFE-treated cells, respectively.  Incubation of macrophages with z-VAD prior to infection did not alter the percentage of cells showing AIF translocation.  Our data suggest that M. bovis-induced CD in bovine macrophages is caspase independent with AIF participation.
Descriptors:  bovine macrophages, Mycobacterium bovis, caspase.

Waters, W.R.; Nonnecke, B.J.; Olsen, S.C.; Palmer, M.V.  Effects of pre-culture holding time and temperature on interferon- gamma responses in whole blood cultures from Mycobacterium bovis-infected cattle.  Veterinary Microbiology.  2007; 119 (2/4): 277-282.  ISSN:  0378-1135
URL:   http://www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  The BovigamTM assay is approved for use within the United States as a complementary tuberculosis test.  Prior to whole blood culture and the ensuing ELISA to detect interferon-(IFN)- gamma, samples are subjected to various holding time/temperature combinations due, in part, to practical constraints associated with shipment of samples to approved laboratories.  To evaluate these effects, 5-month-old Holstein calves (n=7) received 103 cfu Mycobacterium bovis by aerosol.  Heparinized blood was collected 2 months after challenge and held at 4 or 22 degrees C for 0, 8 or 24 h prior to culture with mycobacterial antigens or pokeweed mitogen (PWM).  Responses of samples held for 8 or 24 h were comparable and lower than responses of cultures prepared immediately after collection, regardless of holding temperature.  Differences in responses of samples held at 4 degrees C versus 22 degrees C were also minimal.  A subset of samples was held for 2 h at 37 degrees C at the beginning of the holding period.  This subset of samples had diminished responses to all stimulants and increased holding times (i.e., 24 h versus 8 h) negatively impacted the response.  Pre-processing conditions, particularly delays in set-up and initial high sample temperatures, reduces IFN-gamma responses of cells from infected cattle increasing the risk of false negatives in this assay of regulatory importance.
Descriptors:  young Holstein cattle, experimental infection, aerosol exposure to Mycobacterium bovis, blood analysis, ELISA, assays, IFN-gamma responses, immunological reactions.

Westhusin, M.E.; Shin, T.; Templeton, J.W.; Burghardt, R.C.; Adams, L.G.  Rescuing valuable genomes by animal cloning: a case for natural disease resistance in cattle.  Journal of Animal Science.  2007; 85 (1): 138-142.  ISSN:  0021-8812
URL:   http://www.asas.org
NAL Call Number:  49 J82
Abstract:  Tissue banking and animal cloning represent a powerful tool for conserving and regenerating valuable animal genomes.  Here we report an example involving cattle and the rescue of a genome affording natural disease resistance.  During the course of a 2-decade study involving the phenotypic and genotypic analysis for the functional and genetic basis of natural disease resistance against bovine brucellosis, a foundation sire was identified and confirmed to be genetically resistant to Brucella abortus.  This unique animal was utilized extensively in numerous animal breeding studies to further characterize the genetic basis for natural disease resistance.  The bull died in 1996 of natural causes, and no semen was available for AI, resulting in the loss of this valuable genome.  Fibroblast cell lines had been established in 1985, cryopreserved, and stored in liquid nitrogen for future genetic analysis.  Therefore, we decided to utilize these cells for somatic cell nuclear transfer to attempt the production of a cloned bull and salvage this valuable genotype.  Embryos were produced by somatic cell nuclear transfer and transferred to 20 recipient cows, 10 of which became pregnant as determined by ultrasound at d 40 of gestation.  One calf survived to term.  At present, the cloned bull is 4.5 yr old and appears completely normal as determined by physical examination and blood chemistry.  Furthermore, in vitro assays performed to date indicate this bull is naturally resistant to B. abortus, Mycobacterium bovis, and Salmonella typhimurium, as was the original genetic donor.
Descriptors:  cattle, Brucella abortus, Mycobacterium bovis, Salmonella typhimurium, nuclear transfer, cloned animal, resistance to disease as a genetic trait.  

Witchell, J.; Vordermeier, M.; Wangoo, A.; Goyal, M.  Cytokine mRNA expression levels within BCG vaccinated and non-vaccinated, Mycobacterium bovis challenged cattleImmunology.  2007; 120(Suppl. 1): 69.  ISSN:  0019-2805.  Note:  Annual Congress of the British Society of Immunology, Glasgow, UK; February 20-23, 2007.
URL:  http://www3.interscience.wiley.com/journal/118493028/home?cookieSet=1
Descriptors:  cattle, Mycobacterium bovis, pathogen, lymph nodes, blood and lymphatics, T-helper-type 1 cells,

Xu, Guang Xian; Zhao, De Ming; Zhou, Xiang Mei; Yin, Xiao Min; Yang, Jian Min  Expression of TNF- alpha , iNO, IL-6, and IL-12 in alveolar macrophage contribution by Mce4E protein of Mycobacterium bovis.  Journal of China Agricultural University.  2007; 12 (1): 1-6.  ISSN:  1007-4333.  Note:  In Chinese with an English summary.  
NAL Call Number:  S19.C58
Descriptors:  livestock infection, cell entry proteins, alveolar macrophage, exposure to M. bovis, expression of TNF-alpha, iNO, IL-6 and IL-12, cachectin, cachexin, immunity reactions, immunological reactions, PCR real time, tumor necrosis factor

2006

Aagaard, C.; Govaerts, M.; Meikle, V.; Vallecillo, A.J.; Gutierrez-Pabello, J.A.; Suarez-Guemes, F.; McNair, J.; Cataldi, A.; Espitia, C.; Andersen, P.; Pollock, J.M.  Optimizing antigen cocktails for detection of Mycobacterium bovis in herds with different prevalences of bovine tuberculosis: ESAT6-CFP10 mixture shows optimal sensitivity and specificity.  Journal of Clinical Microbiology (JCM).  2006 Dec; 44 (12): 4326-4335.  ISSN:  0095-1137
URL:   http://jcm.asm.org/
NAL Call Number:  QR46 .J6
Abstract:  Bovine tuberculosis is a major problem in many countries; hence, new and better diagnostic tools are urgently needed. In this work, we have tested ESAT6, CFP10, PE13, PE5, MPB70, TB10.4, and TB27.4 for their potentials as diagnostic markers in field animals from Northern Ireland, Mexico, and Argentina, regions with low, medium, and high prevalences of bovine tuberculosis, respectively.  At all three sites, ESAT6 and CFP10 were superior diagnostic antigens, while their combination performed even better at the two sites where the combination was tested, providing the best coverage for the detection of diseased populations.  The high sensitivity in the skin test reactor groups, combined with the high specificity in the tuberculosis-free groups, indicated that a diagnosis could correctly be made for 85% of the infected animals, based on their responses to these two antigens.  Furthermore, TB10.4, PE13, and PE5 have the potential to supplement ESAT6 and CFP10 in a future five-component diagnostic cocktail.
Descriptors:  cattle, Mycobacterium bovis, diagnostic tools, diagnostic markers, strains from over the world, ESAT6, CFP10 superior antigens, TB10.4, PE13, and PE5.

Abernethy, D.A.; Denny, G.O.; Menzies, F.D.; McGuckian, P.; Honhold, N.; Roberts, A.R.  The Northern Ireland programme for the control and eradication of Mycobacterium bovis.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4):  231-237.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description

NAL Call Number:  SF601.V44
Abstract:  Bovine tuberculosis is endemic in Northern Ireland and a comprehensive eradication scheme has been in operation since 1959.  The current programme involves annual testing, extensive computerized tracing, short-interval testing of herds contiguous to outbreaks and compulsory slaughter of positive cattle.  Despite initial reductions in disease prevalence, eradication has proved elusive and potential explanatory factors include high cattle density and potential for between-herd contact, the impact of exotic diseases on resource priorities, and significant levels of bovine tuberculosis in a wildlife reservoir, the European badger (Meles meles).  Both the role of the infected bovine and that of the badger in spreading disease have to be addressed to ensure progress towards eradication.  Current measures are described and future options for enhancing the programme are outlined.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, disease control, disease control programs, disease surveillance, disease outbreaks, culling animals, herd health, stocking rate, wildlife, disease reservoirs, disease transmission, risk assessment, disease eradication, Northern Ireland.

Ahmed, J.  Transboundary diseases.  Proceedings of the International Conference on the Impact of Endemic and Epidemic Diseases on National, Regional and International Trade, Istanbul, Turkey, February 2006.  Journal of Veterinary Medicine Series B.  2006; 53 (Suppl. 1): 1-42.  ISSN:  0931-1793.  Note:  13 papers,
URL:  http://www3.interscience.wiley.com/journal/120118373/tocgroup
Descriptors:  birds, cattle, transboundry disease, Brucella, foot and mouth disease virus, FMD, Mycobacterium bovis, peste des petits ruminants virus, avian influenza virus, bird flu, bird grippe, cattle plague, disease surveillance, seroepidemiology, poverty-alleviation, EC, EEC, European Communities, European Economic Communities, China, Pakistan, Iran, Iraq, Turkey.

Ahmed, J.  Transboundary diseases. Proceedings of the International Conference on the Impact of Endemic and Epidemic Diseases on National, Regional and International Trade, Istanbul, Turkey, February 2006.  Journal of Veterinary Medicine Series B.  2006; 53 (Suppl. 1): 1-42.  ISSN:  0931-1793.  Note:  13 papers,
URL:   http://www.blackwell-synergy.com/toc/jvb/53/s1
Descriptors:  birds, cattle, diseases that cross political boundries, Brucella, foot and mouth disease virus, FMD, Mycobacterium bovis, peste des petits ruminants virus, avian influenzavirus, bird flu, bird grippe, cattle plague, disease surveillance, seroepidemiology, poverty alleviation, EC, EEC, European Economic Communities, China, Pakistan, Iran, Iraq, Turkey.

Allison, N.  Mycobacterium avium infection in a dog.  Veterinary Medicine.  2006 Jan; 101 (1): 14.  ISSN:  8750-7943
NAL Call Number:  41.8 M69
Descriptors:  dogs, Mycobacterium avium, case studies.

Almeida, Robson F.C.; Madruga, Claudio R.; Soares, Cleber O.; Fernandes, Marta C.; Carvalho, Nilton M.; Jorge, Klaudia S.G.; Osorio, Ana Luiza A.R.  Resposta imune especifica de bovinos experimentalmente sensibilizados com inoculos inativados de Mycobacterium bovis e Mycobacterium avium.  [Specific immune response of cattle to experimental sensibilization by inactivated Mycobacterium bovis and Mycobaceterium avium.]  Pesquisa Veterinaria Brasileira. 2006; 26(4): 195-200.  ISSN:  Note:  In Portuguese.  
NAL Call Number:  SF756.37.B7 P5
Descriptors:  cattle, Mycobacterium bovis, Mycobacterium avium, bacterial pathogens, diagnosis via immune response, bacterial antigens, cervical comparative test, evolution of the specific production of gamma-interferon,identification of interference of unspecified reactions by M. avium, test results.

Amanfu, William.  The situation of tuberculosis and tuberculosis control in animals of economic interestTuberculosis (Amsterdam).  2006; 86 (3-4): 330-335.  ISSN:  1472-9792
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/638428/description?navopenmenu=-2

Descriptors:  animals, tuberculosis, Mycobacterium bovis, public health concerns, veterinary medicine concern, incidence in humans, concerns for disease control in developed and developing countries.

Amaral, A.L. do; Mores, N.; Ventura, L. das V.; Coldebella, A.; Ludke, J.V.; Oliveira, P.A.V. de; Silva, V.S.  Ocorrencia de linfadenite em suinos criados em sistema convencional e cama sobreposta nas fases de crescimento e terminacao.  [Occurrence of lymphadenitis in swine created in conventional and deep-litter system at the growth-termination phase.]  Revista de Ciencias Agroveterinarias.  2006; 5 (1): 64-72.  ISSN:  1676-9732.  Note:  In Portuguese with an English summary.  
URL:  http://www.cav.udesc.br
Descriptors:  pigs; swine housing; piggeries, litter systems compared: T1 deep-litter of wood shaving, T2 deep-litter of rice husk and T3 partially slatted floor; Mycobacterium avium complex; animal pathogens; granulomatous lymphadenitis; feces; liveweight gains.

Aranaz, Alicia; De Juan, Lucia; Bezos, Javier; Alvarez, Julio; Romero, Beatriz; Lozano, Francisco; Paramio, Jose L; Lopez-Sanchez, Jesus; Mateos, Ana; Dominguez, Lucas.  Assessment of diagnostic tools for eradication of bovine tuberculosis in cattle co-infected with Mycobacterium bovis and M-avium subsp. paratuberculosis.  Veterinary Research (Les Ulis).  2006; 37(4): 593-606.  ISSN:  0928-4249
URL:  http://www.vetres.org/
NAL Call Number:  SF602.A5
Descriptors:  Mycobacterium bovis, bovine tuberculosis, Mycobacterium avium ssp. paratuberculosis, dual infected cattle herd, diagnostic tests, field trial, serial parallel testing, comparative IDTB test, IFN-gamma assay, serology of paratuberculosis, detection levels, possible jcross reactivity, need for several diagnostic techniques.

Bannalikar, A.S.; Rishendra Verma.  Characterization of Mycobacterium fortuitum isolates from animals and their environment by PCR-RFLP analysis (PRA) of hsp65 and rpoB genes.  Indian Journal of Animal Sciences.  2006; 76 (2): 109-113.  ISSN:  0367-8318
NAL Call Number:  41.8 IN22
Descriptors:  Mycobacterium fortuitum I and II, isolates of soil, water, animal tissue, biochemical testing, Mycobacterium fortuitum, amplification generated a 439 bp product, RFLP patterns, BSTEII digests, HaeIII digests, MspI digestion, species and subspecies identification.

Barlow, A.M.; Monies, R.J.  Bovine tuberculosis in pigs in Cornwall and the west of England.  Pig Journal. 2006; 58: 204-211
URL:   http://www.thepigsite.com/pigjournal/
Descriptors:  badgers, cattle, pigs, historical pattern of mycobacterial infection, wild and domestic pigs, environmental contamination, Mycobacterium avium from infected birds, Mycobacterium bovis from scavenged dead carcasses or feed and water, ingestion of contaminated milk or milk products, interaction with badgers is a risk, UK

Bennett, R.M.; Cooke, R.J.  Costs to farmers of a tuberculosis breakdown.  Veterinary Record.  2006 Apr. 1; 158 (13): 429-432.  ISSN: 0042-4900
URL:  http://veterinaryrecord.bvapublications.com/
NAL Call Number:  41.8 V641
Descriptors:  cattle, bovine tuberculosis, Mycobacterium bovis, disease outbreaks, costs and returns, England.

Beran, V.; Matlova, L.; Horvathova, A.; Bartos, M.; Moravkova, M.; Pavlik, I.  Mycobacteria in the animal's environment in the Czech Republic.  Veterinarski Arhiv.  2006; 76(Supplement): S33-S39.  ISSN:  0372-5480
URL:   http://www.vef.hr/vetarhiv
NAL Call Number:  41.8 V6416
Descriptors:  farm and captive wild animals, environmental mycobacteria, breeding facilities, tanks, fish aquaria, peat as feed supplement, 1389 samples, 29 sites, bacteria cultured, Stonebrink's medium, Herrold's egg yolk medium, Sula's medium, Mycobacterium avium, Mycobacterium fortuitum, Mycobacterium gordonae, Mycobacterium marinum, Mycobacterium flavescens, zoonotic infections, Czech Republic.

Blissitt, M.J.  The introduction of pre and post-movement TB testing in Scotland for cattle from high incidence TB areasGVJ-Government Veterinary Journal.  2006; 16 (1): 58-64.  ISSN:  0269-5545
URL:   http://www.defra.gov.uk/gvs/publications/gvj/pdf/gvj-vol1701.pdf (PDF | 731KB)
Descriptors:  cattle, high levels of Mycobacterium bovis, zoonotic diseases, testing for disease, control programs, Scotland, Britain, UK.

Brook, R.K.; McLachlan, S.M.  Factors influencing farmers' concerns regarding bovine tuberculosis in wildlife and livestock around Riding Mountain National Park.  Journal of Environmental Management.  2006; 80 (2): 156-166.  ISSN:  0301-4797
URL: http://www.sciencedirect.com/science/journal/03014797
NAL Call Number:  HC75.E5J6
Abstract:  Despite intensive efforts over the last century to eradicate bovine tuberculosis (TB) in North America, several hotspots of infected wildlife and livestock remain, raising concerns that the disease will never be eradicated.  The stress and frustration for a farmer caused by having a herd test positive for TB or living in an infected region can be substantial.  The goal of this study was to investigate the concerns of farmers around Riding Mountain National Park (RMNP) regarding the presence of TB in wildlife and livestock and conduct an exploratory analysis of causal factors.  Data were collected from 786 farmers within 50 km of RMNP using a mail-back questionnaire.  Overall, farmers indicated a high level of concern toward diseases in both wildlife and cattle relative to other concerns.  The spatial variables that had the greatest influence on TB concern were both the distance of farms to the RMNP boundary and distance of farms to previous cases of TB.  The most important aspatial factor associated with high TB concern was the frequency with which farmers observed elk on their land.  These results underscore the important differences between 'objective' measures of risk, such as epidemiological estimates of disease prevalence, and subjective measures of disease concern, such as risk perception and acceptability of management actions.  Written responses suggest that concerns regarding disease may affect how farmers view wildlife on their land and their relationship with neighbouring protected areas.  Management activities that reduce the frequency of elk interactions with farms, but also recognize the complex relationship that farmers have with wildlife and protected areas, will be most effective in mitigating farmer concern regarding this important problem.
Descriptors:  cattle, elk, wildlife disease reservoirs, disease control programs, bovine tuberculosis, farmers/ranchers concerns, disease risks, private and protected lands, Canada.

Bourne, F.J.; Donnelly, C.A.; Cox, D.R.; Gettinby, G.; McInerney, J.P.; Morrison, W.I.; Woodroffe, R.  TB policy and the badger culling trials.  Veterinary Record (London).  2006; 158 (19): 671-672.  ISSN:  0042-4900
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  badgers, cattle, Mycobacterium bovis, wildlife as disease reservoir, culling badgers, disease control policies.

Bourne, F.J.; Donnelly, C.A.; Cox, D.R.; Gettinby, G.; McInerney, J.P.; Morrison, W.I.; Woodroffe, R.  TB policy and the badger culling trials.  Veterinary Record (London).  2006; 158 (12): 418. ISSN:  0042-4900
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  cattle, badgers (Meles meles), wildlife reservoir for Mycobacterium bovis, UK.

Bowen-Davies, J.  Mycobacterium bovis in British deer.  Deer Farming.  2006; (82): 17-21.  
Descriptors:  deer, Mycobacterium bovis, zoonotic infection, active disease surveillance, immunity reactions, lack of diagnostic tests, clinical picture, Capreolus capreolus, red deer (Cervus elaphus), fallow deer (Dama dama), Muntiacus, Mycobacterium bovis, Britain.

Buddle, B.M.; Wedlock, D.N.; Denis, M.  Progress in the development of tuberculosis vaccines for cattle and wildlife.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4) 191-200.  ISSN: 0378-1135. Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  Vaccination against bovine tuberculosis is likely to become an important disease control strategy in developing countries, which cannot afford a test and slaughter control programme, or in countries which have a wildlife reservoir of Mycobacterium bovis infection.  In the past decade, considerable progress has been made in the development and evaluation of tuberculosis vaccines for cattle and for a range of wildlife maintenance hosts including possums, badgers, deer and African buffaloes.  Experimental challenge systems have been established for the different target species and the resulting disease process has mimicked that seen in the field.  In cattle, neonatal vaccination with BCG appeared to be more effective than vaccination of 6-month-old calves and in most situations no other vaccine has been shown to be better than BCG.  However, prime-boost strategies involving combinations of BCG with a protein or DNA vaccine, to improve on BCG vaccination alone, have produced very encouraging results.  Differential diagnostic tests have been developed using mycobacterial antigens that are only present in virulent M. bovis to differentiate between BCG-vaccinated and M. bovis-infected cattle.  BCG vaccine has been shown to reduce the spread of tuberculous lesions in a range of wildlife species and a prototype oral bait delivery system has been developed.  Prospects for the development of improved vaccines against bovine tuberculosis are promising and vaccination approaches could become very valuable in the control and eradication of bovine tuberculosis.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, vaccines, vaccine development, wild animals, wildlife vaccination program, animal diseases, tuberculosis, vaccination, disease control, disease control programs, disease reservoirs, BCG vaccine, virulence, disease diagnosis, diagnostic techniques.

Buick, W.  TB in domestic species other than cattle and badgers.  GVJ Government Veterinary Journal.  2006; 16 (1): 87-91.  ISSN:  0269-5545
URL:  http://www.defra.gov.uk/gvs/publications/gvj/pdf/gvj-vol1701.pdf (PDF | 731KB)
Descriptors:  badgers (Meles meles), Camelidae, cats, cattle, dogs, ferrets, goats, sheep, horses, pigs, Mycobacterium bovis, clinical picture, susceptibility to pathogen.

Buncic, S.  Zoonotic diseases in farm animals.  Integrated Food Safety and Veterinary Public Health. 2006: 57-76.  ISBN:  0851999085; 9780851999081.  Note:  Book chapter.  
NAL Call Number:  RA601.S28 2006
Descriptors:  farm animals, livestock, animal and human diseases, disease transmission, epidemiology bovine spongiform encephalopathy, prion diseases, brucellosis, glanders, listeriosis, mycoses, parasitoses, protozoal infections; tuberculosis, viral diseases, zoonoses, avian influenza virus; Brucella abortus, Brucella suis, Burkholderia mallei, Erysipelothrix rhusiopathiae, Listeria, Mycobacterium bovis; Mycobacterium tuberculosis, Taenia saginata, Taenia solium, Trichinella pseudospiralis, West Nile virus, zoonoses.

Buxton, David.  Wildlife and the risk to humans and domestic animals: A case for disease surveillanceVeterinary Journal.  2006; 171 (2): 204-205.  ISSN:  1090-0233
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/623077/description#description
NAL Call Number:  SF601.V484
Descriptors:  wildlife as disease reservoirs, zoonotic diseases, humans, domestic animals, parasites, bison, wolf, red deer, reindeer, sika deer, elk, Mycobacterium bovis, nematodes, sarcosystis.

Cassidy, J.P.  The pathogenesis and pathology of bovine tuberculosis with insights from studies of tuberculosis in humans and laboratory animal models.  Veterinary Microbiology.  2006. 112 (2-4): 151-161.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44

Abstract:
  This paper reviews key insights the discipline of pathology has contributed to our understanding of bovine tuberculosis in the context of findings of studies of tuberculosis in humans and laboratory animal models.  Analysis and extrapolation of data from other species have the potential to expand our understanding of the pathogenesis of the disease in cattle.  The distribution of lesions in affected cattle, humans and laboratory animals illustrate the primacy of the respiratory tract as portal of infection and raise questions about the role of the upper respiratory tract surface, tonsil and dorsal lung regions in disease pathogenesis and transmission.  The mechanisms behind significant pathological processes such as necrosis, apoptosis and liquefaction, occurring within lesions, are explored and their potential practical significance assessed in the context of herd disease dynamics and vaccine development.  It is proposed that effective 'innate' host defenses result in many animals and humans remaining disease-free and tuberculin test negative following exposure to infection.  Furthermore, the concepts of latency and disease reactivation, considered significant factors in perpetuating tuberculosis in human populations, are explored in the context of the bovine disease.

Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, animal disease models, pathogenesis, humans, tuberculosis, zoonoses, alternative hosts, respiratory system, disease course, infection, necrosis, apoptosis, resistance mechanisms, latent period, relapse, liquefaction.

Cataluna, R.L.N.; Gordoncillo, M.J.N.  Cervical fold tuberculin testing in cattle (Bos indicus) and water buffaloes (Bubalus bubalis) in Los Banos, Laguna.  Philippine Journal of Veterinary Medicine.  2006; 43 (2): 103-105.  ISSN:  0031-7705
Descriptors:  water buffalo, cattle, bovine tuberculosis, Mycobacterium bovis, disease surveillance, PPD tuberculin test, bacterial testing, zoonotic potential, Philippines.

Cockle, P.J.; Gordon, S.V.; Hewinson, R.G.; Vordermeier, H.M.  Field evaluation of a novel differential diagnostic reagent for detection of Mycobacterium bovis in cattle.  Clinical and Vaccine Immunology.  2006; 13 (10): 1119-1124.  ISSN:  1556-6811
URL:  http://cvi.asm.org/
Descriptors:  cattle; Mycobacterium bovis; immunodominant peptides from Rv3873, Rv3879c, Rv0288, Rv3019c; lead diagnostic antigens ESAT-6 and CFP-10; peptide cocktail; better than M. bovis BCG vaccination; serological diagnosis.

Collins, J.D.  The approach to eradication of tuberculosis in cattle: an Irish perspective.  Cattle Practice.  2006; 14 (1): 1-6.  ISSN:  0969-1251
NAL Call Number:  SF961.C37
Abstract:  With regards to tuberculosis in cattle, the challenge to Irish agriculture is to ensure that all the stakeholders realize that without their full participation, the persistence of this disease in the national herd will continue to be a drain on the national economy and will threaten Ireland's ability to trade internationally as a supplier of high quality beef and dairy products at some time in the future.  Scientific evaluation of data from the past 30 years indicates that eradication is achievable on a regional and national basis.  This is provided the status of clear herds is maintained through vigilance and active cooperation between herd owners and the regulatory authorities and that a holistic approach to eradication is supported by effective risk communication at local and national level, and that defined and agreed targets are adopted and achieved on schedule.  The respective roles of members of the veterinary profession in government service and, in particular, of those engaged by the owners of herds that are clear of tuberculosis and by owners of infected herds, demand a professional performance of the highest standard and the exercise of due diligence at every level to ensure the prevention, control and eradication of this zoonotic disease.
Descriptors:  beef cattle, dairy cattle, Mycobacterium bovis, impact of disease on trade, dairy and beef product quality, role of veterinarians, disease prevention and control programs, Irish Republic. 

Collins, J.D.  Tuberculosis in cattle: strategic planning for the future.  Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 369-381.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  In the later stages of eradication of tuberculosis in cattle there is a need to take account of the fact that Mycobacterium bovis infection in cattle presents, not as cases of clinical disease but most commonly as apparently healthy animals showing an immunological response to tuberculin.  This is an entirely different scenario to that seen when national eradication programmes were first devised, at a time when the protection of public health rather than animal health was the prime motivation.  In countries with active programmes to eradicate bovine tuberculosis, it is critical for the programme's success that account is taken of this redefinition of tuberculosis, side by side with changes in modern animal production systems and their impact on the transmission of M. bovis.  This paper highlights factors critical to the success of a national eradication programme, including a clear identification of the goals, of the policies that guide actions, and of the sequences of actions that are required within the programme to accomplish these goals.  Experience has illustrated the adverse effects of compromise on outcome when the application of fundamental principles of disease control such as sound animal management, removal of known sources of infection, early diagnosis, quarantine, movement control and environmental hygiene are less than enthusiastically promoted and applied.  The reality is that where these principles are applied in a sustained manner, the outcome is more likely to be successful.  Therein lies the challenge for the risk manager.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, program planning, disease control programs, decision making, latent period, animal husbandry, disease transmission, agricultural policy, control methods, risk management, health policy, pathogen eradication.

Corner, L.A.L.  The role of wild animal populations in the epidemiology of tuberculosis in domestic animals: how to assess the risk.  Veterinary Mcrobiology.  2006 Feb. 25; 112 (2-4): 303-312.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  Tuberculosis is present in wild animal populations in North America, Europe, Africa and New Zealand.  Some wild animal populations are a source of infection for domestic livestock and humans.  An understanding of the potential of each wild animal population as a reservoir of infection for domestic animals is reached by determining the nature of the disease in each wild animal species, the routes of infection for domestic species and the risk of domestic animals encountering an infectious dose.  The mere presence of infection in a wild animal population does not of itself provide evidence of a significant wildlife reservoir.  Although at times counterintuitive, wildlife populations with high disease prevalence may not necessarily have a role in the epidemiology of disease in domestic livestock.  The key concepts used in deciding whether an infected wild animal population is involved in the epidemiology of tuberculosis in domestic livestock is illustrated by reference to six well-researched cases: the feral pig (Suis scrofa) and feral Asian water buffalo (Bubalus bubalis) in Australia, white tailed deer (Odocoileus virginianus) in Michigan, and the brushtail possum (Trichosurus vulpecula) and other species, such as the ferret (Mustela furo), in New Zealand.  A detailed analysis of Mycobacterium bovis infection in the Eurasian badger (Meles meles) in Ireland and their role as a reservoir of infection for cattle is also presented.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, wild animals, wildlife, animal diseases, tuberculosis, alternative hosts, risk assessment, disease transmission, infection, disease prevalence, disease outbreaks, case studies, disease reservoirs.

Coryn, H.D.  Badgers, TB and modern farming practice.  Veterinary Record.  2006; 158 (17): 604.  ISSN:  0042-4900.  Note:  Correspondence.
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  cattle, badgers (Meles meles), Mycobacterium bovis, relationship with modern farming practices, UK.

Cvetnic, Z.; Ocepek, M.; Lojkic, M.; Markus Cizelj, L.; Spicic, S.; Pate, M.; Krt, B.  Usporedba tuberkulinskog i Mycobacterium bovis gama interferonskog ( gamma -IFN) testa u dijagnostici i tuberkuloze goveda.  [Comparison of tuberculin skin test and Mycobacterium bovis gamma interferon ( gamma -IFN) test in diagnosis of bovine tuberculosis.]  Praxis Veterinaria Zagreb.  2006; 54 (1/2): 41-49.  ISSN:  0350-4441.  Note:  In Croatian with an English summary.  
Descriptors:  cattle, tuberculin skin test and gamma interferon diagnostic tests, comparison study, Mycobacterium bovis.

Cvetnic, Z.; Spicic, S.; Katalinic-Jankovic, V.; Marjanovic, S.; Obrovac, M.; Benic, M.; Mitak, M.; Pavlik, I.  Mycobacterium caprae infection in cattle and pigs in one family farm in Croatia: a case report.  Veterinarni Medicina.  2006; 51 (11): 523-531.  ISSN:  
URL:  http://vetmed.vri.cz
NAL Call Number:  41.9 C333
Descriptors:  cattle, pigs, Mycobacterium caprae, family farm, tuberculin skin test, bovine PPD, postmortem exam, submandibular lymphnode lesions, isolates identified, classical and molecular methods, first case of Mycobacterium caprae in pigs, Croatia.

Daykin, J.; Pepper, B.; Green, R.; Howe, C.; Swarbrick, O.  Badger culling consultation. Veterinary Record (London).  2006; 159 (7): 220.  ISSN:  0042-4900
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  badgers, cattle, Mycobacterium bovis, bovine tuberculosis, rules, UK.

de la Rua Domenech, R.; Goodchild, A.T.; Vordermeier, H.M.; Hewinson, R.G.; Christiansen, K.H.; Clifton-Hadley, R.S.  Ante mortem diagnosis of tuberculosis in cattle: A review of the tuberculin tests, (Sd(B-interferon assay and other ancillary diagnostic techniques.  Research in Veterinary Science.  2006 Oct; 81 (2): 190-210.  ISSN:  0034-5288
URL:  http://dx.doi.org/10.1016/j.rvsc.2005.11.005
NAL Call Number:  41.8 R312
Abstract:  The early, preclinical stages of bovine TB can be detected in live animals by the use of tests of cellular immunity (the skin, (Sd(B-interferon and lymphocyte transformation tests).  Tests of humoral (antibody) immunity, Mycobacterium bovis PCR probes on early tissue cultures or live cattle specimens, and tests based on "electronic nose" technology have been developed more recently.  The key measure of diagnostic test accuracy is the relationship between sensitivity and specificity, which determines the false-positive and false-negative proportions.  None of the tests currently available for the diagnosis of bovine TB allow a perfectly accurate determination of the M. bovis infection status of cattle.  Although various factors can reduce the sensitivity and specificity of the skin tests, these remain the primary ante mortem diagnostic tools for TB in cattle, providing a cost-effective and reliable means of screening entire cattle populations.  Despite the inescapable limitations of existing diagnostic tests, bovine TB has been effectively eradicated from many developed countries and regions with the implementation of sound programmes of regular tuberculin skin testing and removal of reactors, coupled with slaughterhouse surveillance for undetected infections, repeat testing and culling of infected herds, cattle movement restrictions to prevent introduction of infected animals and occasional slaughter of entire herds with intractable breakdowns. This is likely to remain the mainstay of bovine TB control programmes for the foreseeable future.  Additionally, newer ancillary in vitro diagnostic assays are now available to TB control programme managers to supplement the skin tests in defined circumstances according to the specific disease situation in each country or region.  The strategic deployment of ancillary in vitro tests alongside the primary skin tests has enhanced the detection of M. bovis-infected cattle and reduced the number of animals slaughtered as false positives.
Descriptors:  cattle, bovine tuberculosis; Mycobacterium bovis, disease diagnosis, tuberculin, interferons, diagnostic techniques, humoral immunity, PCR, polymerase chain reaction, literature reviews, skin tests, lymphocyte proliferation, electronic nose, accuracy, disease control programs, test specificity, test sensitivity,

Diguimbaye Djaibe, Colette; Hilty, Markus; Ngandolo, Richard; Mahamat, Hassane H.; Pfyffer, Gaby E.; Baggi, Franca; Hewinson, Glyn; Tanner, Marcel; Zinsstag, Jakob; Schelling, Esther.  Mycobacterium bovis isolates from tuberculous lesions in Chadian zebu carcassesEmerging Infectious Diseases.  2006; 12 (5): 769-771.  ISSN:  1080-6040.
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?linkbar=plain&db=journals&term=1080-6040
NAL Call Number:  RA648.5.E46
Descriptors:  zebu cattle, Arabe breed, Mboboro breed, kouri breed, Mycobacterium bovis, Mycobacterium bovis, slaughterhouse study, breed differences, trans-border and ongoing transmission indicated, Chad, Cameroon, Nigeria.

Donnelly, C.A.; Woodroffe, R.; Cox, D.R.; Bourne, F.J.; Cheeseman, C.L.; Clifton-Hadley, R.S.; Wei, G.; Gettinby, G.; Gilks P.; Jenkins H.  Positive and negative effects of widespread badger culling on tuberculosis in cattle \h [electronic resource].  Nature.  2006 Feb. 16; 439 (7078): 843-846.  ISSN:  1476-9679
URL: http://dx.doi.org/10.1038/nature04454
NAL Call Number:  472 N21
Descriptors:  cattle, bovine tuberculosis, Mycobacterium bovis, disease control, disease reservoirs, badgers, Meles meles, culling animals, disease prevalence, disease incidence, geographical distribution, United Kingdom.

Everett, R.E.  Eradication of bovine TB: learning from other countries.  Veterinary Record (London).  2006; 158 (18): 640.  ISSN:  0042-4900
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  buffalo, cattle, bovine tuberculosis, Mycobacterium bovis, disease control and eradication, Australia, New South Wales, Northern Territory, Queensland, Western Australia.

Fischer, O.A.; Matlova, L.; Dvorska, L.; Svastova, P.; Bartos, M.; Weston, R.T.; Pavlik, I.  Various stages in the life cycle of syrphid flies (Eristalis tenax; Diptera: Syrphidae) as potential mechanical vectors of pathogens causing mycobacterial infections in pig herds.  Folia Microbiologica.  2006; 51 (2): 147-153
URL:  http://www.biomed.cas.cz/mbu/folia/
Descriptors:  pigs, syrphid flies, Eristalis tenax, insect vectors, disease carriers, survival and transmission, Mycobacterium chelonae, Mycobacterium avium ssp avium, Mycobacterium avium ssp hominissuis.

Foote, M.; Nonnecke, B.; Waters, W.; Beitz, D.; Fowler, M.; Johnson, T.; Miller, B.  High growth rate fails to enhance adaptive immune responses of neonatal calves and is associated with decreased T cell viability.  Journal of Animal Science.  2006; 84 (Suppl. 1): 163-164.  ISSN:  0021-8812.  Note:  2006 ADSA/ASAS Joint Annual Meeting, Minneapolis, MN, USA; July 09 -13, 2006 
URL:  http://www.asas.org
NAL Call Number:   49 J82
Descriptors:  cattle, neonates, Mycobacterium bovis, growth rates, serum testing, adaptive immune response, decreased T cell viability, CD4 Positive T cells, CD8 positive T cells, mononuclear leukocytes.

Gagea, M.I.; Bateman, K.G.; Van Dreumel, T.; McEwen, B.J.; Carman, S.; Archambault, M.; Shanahan, R.A.; Caswell, J.L.  Diseases and pathogens associated with mortality in Ontario beef feedlots.  Journal of Veterinary Diagnostic Investigation.  2006 Jan; 18 (1) 18-28.  ISSN: 1040-6387
URL:  http://jvdi.org/
NAL Call Number:  SF774.J68
Descriptors:  calves, beef cattle, cattle diseases, animal pathogens, animal feeding operations, feedlots, disease incidence, disease prevalence, disease detection, bacterial infections, zoonotic viral diseases, Mycobacterium bovis, Mannheimia haemolytica, Haemophilus somnus, respiratory tract diseases, bacterial pneumonia, morbidity, mortality, bovine viral diarrhea virus, arthritis, pneumonic pasteurellosis, emerging diseases, Ontario

Gallagher, J.; Muirhead, R.H.; Turnbull, A.T.; Davies, J.I.; Ashton, W.L.G.; Smith, J.; Daykin, J.; McDiarmid, A.  TB policy and the badger culling trials.  Veterinary Record (London).  2006; 158 (9): 310-311.  ISSN:  0042-4900
URL:   www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  badgers, (Meles meles), cattle, Mycobacterium bovis, disease eradication and control, government policies, UK.

Gallagher, J.; Muirhead, R.H.; Turnbull, A.T.; Davies, J.I.; Ashton, W.L.G.; Smith, J.; Daykin, J.; McDiarmid, A.  TB policy and the badger culling trialsVeterinary Record (London).  2006; 159 (7): 220.  ISSN:  0042-4900
URL:   www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  badgers, Mycobacterium bovis, bovine tuberculosis, policies, wildlife disease reservoirs, disease transmission, culling of badgers.

Gallagher, J.; Muirhead, R.H..; Turnbull, A.T.; Davies, J.I.; Ashton, W.L.G.; Smith, J.; Daykin, J.; McDiarmid, A.  TB policy and the badger culling trials.  Veterinary Record (London).  2006; 158 (15): 524.  ISSN:  0042-4900
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  badgers (Meles meles), cattle, Mycobacterium tuberculosis.

Ganesan, P.I.  Excretion of mycobacteria in cattleIndian Veterinary Journal.  2006; 83 (10): 1112-1113.  ISSN:  0019-6479
URL:  www.indvetjournal.com
NAL Call Number:  41.8 IN2
Descriptors:  cattle, identification of infected animals, respiratory excretion of Mycobacterium bovis, nasal swab smears, SID test, intradermal tuberculin, experimental infection.

Gobena Ameni; Abraham Aseffa; Engers, H.; Young, D.; Hewinson, G.; Vordermeier, M.  Cattle husbandry in Ethiopia is a predominant factor affecting the pathology of bovine tuberculosis and gamma interferon responses to mycobacterial antigens.  Clinical and Vaccine Immunology. 2006; 13 (9): 1030-1036.  ISSN:  1556-6811
URL:  http://cvi.asm.org/
Abstract:  Bovine tuberculosis is a major economic problem and a potential public health risk. Improved diagnostics like the gamma interferon (IFN-gamma ) test with ESAT6 and/or CFP10 could contribute to the control program.  We assessed IFN- gamma responses in zebu (Ethiopian Arsi breed) and Holstein cattle kept indoors or in a pasture to tuberculin purified protein derivative (PPD) and an ESAT6-CFP10 protein cocktail.  Furthermore, the intensity and distribution of pathology of bovine tuberculosis were compared between the two breeds.  Our data demonstrated significantly (all P<0.02) higher IFN- gamma  responses to avian PPD, bovine PPD, and the ESAT6-CFP10 protein cocktail in Holstein than in zebu cattle, while lesion severities in infected animals and tuberculin skin test responses did not differ significantly (P>0.05) between the two breeds.  Holstein cattle that were kept indoors produced significantly (all P<0.01) higher IFN- gamma levels in response to avian PPD, bovine PPD, and the ESAT6-CFP10 protein cocktail than did Holstein cattle kept in a pasture.  Moreover, lesion severity was significantly higher in Holstein cattle kept indoors (P=0.001) than in those kept in the pasture.  Lesions were localized predominantly in the digestive tract in cattle kept in a pasture, while they were localized in the respiratory tract in cattle kept indoors.  In conclusion, in Holstein cattle, husbandry was a dominant factor influencing the severity of tuberculosis lesions and IFN-gamma responses to mycobacterial antigens compared to breed.  A difference in the cellular immune response between zebu and Holstein cattle was observed, while tuberculosis lesion severities were identical in the two breeds, when both were kept in a pasture..
Descriptors:  zebu cattle, Holstein cattle, Mycobacterium bovis, zebu, indoor housing, pastured animals, improved diagnostics, gamma interferon (IFN-gamma ) test with ESAT6 and/or CFP10, Ethiopia, Abyssinia.

Godden, S.; McMartin, S.; Feirtag, J.; Stabel, J.; Bey, R.; Goyal, S.; Metzger, L.; Fetrow, J.; Wells, S.; Chester-Jones, H.  Heat-treatment of bovine colostrum. II: Effects of heating duration on pathogen viability and immunoglobulin G.  Journal of Dairy Science.  2006 Sept; 89 (9): 3476-3483.  ISSN:  0022-0302
NAL Call Number:  44.8 J822
Abstract:  Batches (30-L) of first-milking bovine colostrum, inoculated with Mycoplasma bovis (10 superscript 8(B cfu/mL), Listeria monocytogenes (10 superscript 6(B cfu/mL), Escherichia coli O157:H7 (10 superscript 6(B cfu/mL), Salmonella enteritidis (10 superscript 6(B cfu/mL), and Mycobacterium avium subsp. paratuberculosis (Map; 10 superscript 3(B cfu/mL), were heat-treated at 60AC for 120 min in a commercial on-farm batch pasteurizer system.  Duplicate 50-mL subsamples of colostrum were collected at 15-min intervals throughout the heat-treatment process for the purpose of bacterial culture and for measurement of IgG concentration (mg/mL) and antibody activity [log subscript 2(B(bovine viral diarrhea virus type 1 serum neutralization titer)].  Four replicate batches of colostrum were run for each of the 5 pathogens studied.  There was no effect of heating moderate- to high-quality colostrum at 60AC for at least 120 min on mean IgG concentration (pre = 60.5 mg/mL; post = 59.1 mg/mL).  Similarly, there was no effect of heat-treatment on the mean log subscript 2(B bovine viral diarrhea virus type 1 serum neutralization titer (pre = 12.3; post = 12.0). Viable M. bovis, L. monocytogenes, E. coli O157:H7, and S. enteritidis added to colostrum could not be detected after the colostrum was heat-treated at 60AC for 30 min.  Average bacteria counts showed that Map was not detected when batches were heated at 60AC for 60 min.  Although the authors believe that heat-treating colostrum at 60AC for 60 min should be sufficient to eliminate Map from colostrum in most situations, further research is needed to determine whether these findings may be replicated, given that variability was observed in Map culture results.
Descriptors:  first milking colostrum, inoculation with Mycoplasma bovis, Mycobacterium avium paratuberculosis, Salmonells enteritidis, Listeria monocytogenes, Escherichia coli, heat treatment process to inactivate the pathogens.

Godden, S.; McMartin, S.; Feirtag, J.; Stabel, J.; Bey, R.; Goyal, S.; Metzger, L.; Fetrow, J.; Wells, S.; Chester-Jones, H.  Heat-treatment of bovine colostrum. II: Effects of heating duration on pathogen viability and immunoglobulin G.  Journal of Dairy Science.  2006 Sept; 89 (9): 3476-3483.  ISSN:  0022-0302
URL:  http://jds.fass.org/cgi/content/full/89/9/3476
NAL Call Number:  44.8 J822
Abstract:  Batches (30-L) of first-milking bovine colostrum, inoculated with Mycoplasma bovis (10 superscript 8(B cfu/mL), Listeria monocytogenes (10 superscript 6(B cfu/mL), Escherichia coli O157:H7 (10 superscript 6(B cfu/mL), Salmonella enteritidis (10 superscript 6(B cfu/mL), and Mycobacterium avium subsp. paratuberculosis (Map; 10 superscript 3(B cfu/mL), were heat-treated at 60AC for 120 min in a commercial on-farm batch pasteurizer system.  Duplicate 50-mL subsamples of colostrum were collected at 15-min intervals throughout the heat-treatment process for the purpose of bacterial culture and for measurement of IgG concentration (mg/mL) and antibody activity [log subscript 2(B(bovine viral diarrhea virus type 1 serum neutralization titer)].  Four replicate batches of colostrum were run for each of the 5 pathogens studied.  There was no effect of heating moderate- to high-quality colostrum at 60AC for at least 120 min on mean IgG concentration (pre = 60.5 mg/mL; post = 59.1 mg/mL).  Similarly, there was no effect of heat-treatment on the mean log subscript 2(B bovine viral diarrhea virus type 1 serum neutralization titer (pre = 12.3; post = 12.0). Viable M. bovis, L. monocytogenes, E. coli O157:H7, and S. enteritidis added to colostrum could not be detected after the colostrum was heat-treated at 60AC for 30 min.  Average bacteria counts showed that Map was not detected when batches were heated at 60AC for 60 min.  Although the authors believe that heat-treating colostrum at 60AC for 60 min should be sufficient to eliminate Map from colostrum in most situations, further research is needed to determine whether these findings may be replicated, given that variability was observed in Map culture results.
Descriptors:  first milking colostrum, inoculation with Mycoplasma bovis, Mycobacterium avium paratuberculosis, Salmonells enteritidis, Listeria monocytogenes, Escherichia coli, heat treatment process to inactivate the pathogens.

Gomes da Silva, Paulo Eduardo; Pinheiro, Sonia Regina; Lizandra do Rego Leal, Marta; Bertagnon, Heloisa Godoi; Pinto-Coelho-Motta, Pedro Moacyr; Sinhorini, Idercio Luiz; Vasconcellos, Silvio-Arruda; Benesi, Fernando Jose.  Teste de tuberculinizacao em caprinos (Capra hircus) experimentalmente sensibilizados. [Tuberculin test in experimentally sensitized goats (Capra hircus)]  Ciencia Rural.  2006; 36 (3): 880-886.  ISSN:  0103-8478.  Note:  In Portuguese.
URL:  http://www.scielo.br/scielo.php/script_sci_serial/pid_0103-8478/lng_en/nrm_iso
NAL Call Number: S192.R4
Descriptors:  goats, 3 groups, Myobacterium avium D4, Mycobacterium bovis AN5, control with saline, tuberculin testing, skin sampling, mononuclear inflammatory infiltrate of 96h after tuberculin inoculation.

Gopal, R.; Goodchild, A.; Hewinson, G.; Domenech, R. de la R.; Clifton-Hadley, R.  Introduction of bovine tuberculosis to north-east England by bought-in cattle.  Veterinary Record (London).  2006; 159 ( 9): 265-271.  ISSN:  0042-4900
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  cattle herds, bovine tuberculosis, Mycobacterium bovis, restocking after FMD in 2001, infected purchased animals, spoligotype and variable numbe tandem repeats indicated souce was Wales, Cheshire herds, Irish imports, Britain, England.

Good, M.  Bovine tuberculosis eradication in Ireland.  Irish Veterinary Journal.  2006; 59 (3): 154-162.  ISSN:  0368-0762
URL:  www.veterinary-ireland.org
NAL Call Number:  41.8 IR4
Descriptors:  cattle, bovine tuberculosis, eradication program started in 1950, European trading condition for live animals, reduction in disease levels, Mycobacterium bovis levels, wild badgers (Meles meles), disease reservoirs, disease transmission, disease prevention and control in wild animals, Ireland.

Gormley, E.; Doyle, M.B.; Fitzsimons, T.; McGill, K.; Collins, J.D.  Diagnosis of Mycobacterium bovis infection in cattle by use of the gamma-interferon (Bovigam) assay.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4) 171-179.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  The strategic use of the gamma-interferon (IFN-gamma) assay (Bovigam) can provide a means for the early identification of Mycobacterium bovis infected cattle, thus ensuring their removal from an infected herd.  When used in parallel with the tuberculin test, it is capable of identifying infected cattle, which might otherwise not be detected until later, if at all.  The early detection and removal of these animals reduces the risk that they will become a source of infection for other cattle.  When targeted in herds of high prevalence the benefits to the herd owner directly concerned can be considerable as the assay provides a means of shortening the period of restriction for such herds.  This serves to generate confidence among herd owners and other stakeholders that effective schemes, based on sound scientific principles, can be developed to eradicate tuberculosis from infected cattle populations.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease diagnosis, interferons, diagnostic techniques, tuberculin, culling animals, early diagnosis, disease transmission, disease prevalence, disease control, disease control programs.

Gordejo, F.J. Reviriego.; Vermeersch, J.P.  Towards eradication of bovine tuberculosis in the European Union.  Veterinary Microbiology.  2006; 112 (2-4, Sp. Iss. SI): 101-109.  ISSN:  0378-1135
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description

NAL Call Number:  SF601.V44
Descriptors:  eradication of bovine tuberculosis, historical review, legislation, cattle trade, cattle breeding systems, environmental condition, epidemiology, Mycobacterium bovis, summary of the current statue of the disease, EU policies.

Griffin, J.F.T.; Rodgers, C.R.; Liggett, S.; Mackintosh, C.G.  Tuberculosis in ruminants: characteristics of intra-tonsilar Mycobacterium bovis infection models in cattle and deer.  Tuberculosis.  2006; 86 (6): 404-418.  ISSN:  1472-9792
URL:  http://www.sciencedirect.com/science/journal/14729792
Descriptors:  cattle, red deer (Cervus elaphus), Mycobacterium bovis, intra-tonsilar, immunity reactions, immunological reactions, resistance to disease, susceptibility to disease, species comparison.

Hancox, M.  Confusion over cattle tuberculosis.  Letters in Applied Microbiology.  2006; 43 (2): 236.  ISSN:  0266-8254
URL:  http://www3.interscience.wiley.com/journal/118581679/abstract
Descriptors:  badgers (Meles meles), cattle, Mycobacterium tuberculosis, species differences in lung lesions, transmission between cattle and badgers, routes of infection.

Hermoso de Mendoza, J.; Parra, A.; Tato, A.; Alonso, J.M.; Rey, J.M.; Pena, J.; Garcia-Sanchez, A.; Larrasa, J.; Teixido, J.; Manzano, G.  Bovine tuberculosis in wild boar (Sus scrofa), red deer (Cervus elaphus) and cattle (Bos taurus) in a Mediterranean ecosystem (1992-2004).  Preventive Veterinary Medicine.  2006 May 17; 74 (2-3): 239-247.  ISSN:  0167-5877
URL:  http://dx.doi.org/10.1016/j.prevetmed.2005.10.005
NAL Call Number:  SF601.P7
Descriptors:  cattle, cattle diseases, wild boars, Sus scrofa, red deer, Cervus elaphus, paratuberculosis, Mycobacterium bovis; epidemiological studies, disease transmission, wildlife livestock relations, game animals, risk assessment, ecosystems, disease surveillance, disease prevalence, disease detection, wildlife management, Spain.

Hewinson, R.G.; Vordermeier, H.M.; Smith, N.H.; Gordon, S.V.  Recent advances in our knowledge of Mycobacterium bovis: a feeling for the organism.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4): 127-139.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  Significant and rapid progress has been made in our knowledge and understanding of Mycobacterium bovis since the last international M. bovis conference 5 years ago.  Much of this progress has been underpinned by the completion of the genome sequence.  This important milestone has catalysed research into the development of a number of improved tools with which to combat bovine tuberculosis.  In this article we will review recent progress made in the development of these tools and in our understanding of the organism, its evolution and spread.  Comparison of the genome sequence with those of other members of the Mycobacterium tuberculosis complex has enabled insights into the evolution of M. bovis.  This analysis also indicates that the M. tuberculosis complex have the propensity to adapt to new host species.  The use of high throughput molecular typing methods has revealed that the recent bovine tuberculosis epidemic in Great Britain is being driven by a number of clonal expansions, which cannot be explained by random mutation and drift alone.  Completion of a number of mycobacterial genome sequences has allowed the development of antigen mining techniques that rapidly identify M. bovis-specific genes.  These can then be used as reagents in the gamma interferon assay to increase the specificity of the assay and also to discriminate between Bacillus of Calmette and Guerin (BCG) vaccinated animals and those infected with M. bovis.  In the longer term, comparisons between the genomes of M. bovis and BCG will allow insight into how BCG became attenuated following serial passage on artificial growth media and reveal clues into how to improve the vaccine efficacy of BCG.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, genomics, nucleotide sequences, microbial genetics, genome, evolution, host range, adaptation, disease outbreaks, genetic drift, bacterial antigens, BCG vaccine, vaccination, molecular sequence data.  

Hines, N.; Payeur, J.B.; Hoffman, L.J.  Comparison of the recovery of Mycobacterium bovis isolates using the BACTEC MGIT 960 system, BACTEC 460 system, and Middlebrook 7H10 and 7H11 solid media.  Journal of Veterinary Diagnostic Investigation.  2006 May; 18 (3): 243-250.  ISSN: 1040-6387
URL:  http://jvdi.org/
NAL Call Number:  SF774.J68
Descriptors:  cattle, lymph nodes, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, strains, pathogen identification, diagnosis, culture media, tissue analysis, niacin, nitrates, microbial contamination, disease detection, new methods.

Horwitz, Marcus A.; Harth, Guenter; Dillon, Barbara Jane; Maslesa-Galic, Sasa.  A novel live recombinant mycobacterial vaccine against bovine tuberculosis more potent than BCG.  Vaccine.  2006; 24 (10): 1593-1600.  ISSN:  0264-410X URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/30521/description#description
Descriptors:  vaccination, cattle, other domesticated animal diseases, wild animal as disease reservoirs, Mycobacterium bovis, live recombinant vaccine, rBCG30 expresses large amounts of the Mycobacterium tuberculosis, 30kDa major secretory protein, more efficacious against bovine tuberculosis than BCG, aerosol challenge.

Jahans, K.; Worth, D. The laboratory diagnosis of bovine tuberculosis.  GVJ-Government Veterinary Journal.  2006; 16 (1): 53-57.  ISSN:  0269-5545
URL:   http://www.defra.gov.uk/gvs/publications/gvj/pdf/gvj-vol1701.pdf (PDF | 731KB)
Descriptors:  cattle, Mycobacterium bovis, diagnosis, intradermal tests, PCR, zoonotic infections.

Johnson, Linda; Gough, Julie; Spencer, Yvonne; Hewinson, Glyn; Vordermeier, Martin; Wangoo, Arun. Immunohistochemical markers augment evaluation of vaccine efficacy and disease severity in bacillus Calmette-Guerin (BCG) vaccinated cattle challenged with Mycobacterium bovis.  Veterinary Immunology and Immunopathology.  2006; 111(3-4): 219-229.  ISSN:  0165-2427.
URL:  http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number:  SF757.2.V38
Abstract:  Development of necrotic granulomas in response to Mycobacterium bovis infection in cattle is pathognomonic for bovine tuberculosis.  Previously our laboratory reported on M. bovis granuloma classification by stage of lesion advancement within bovine lymph nodes and developed immunohistochemical markers to further characterize these granulomas.  In this study of bovine lymph node granulomas we applied this classification system to assess the dynamics of vaccination challenge.  Lymph nodes collected from cattle vaccinated with M. bovis bacillus Calmette-Guerin (BCG) and subsequently challenged with virulent M. bovis were compared to lymph nodes from unvaccinated, challenged cattle.  Expression of interferon-(Sd(B (IFN-(Sd(B), transforming growth factor-(Sb(B (TGF-(Sb(B), type I procollagen and cell marker identification of T cells, B cells, macrophages and WC1+(Sd(Bdelta TCR+ cells were assessed.  Granulomas formed in vaccinated cattle were greatly reduced in number, area, degree of necrosis and peripheral fibrosis and contained fewer Langhans' giant cells, acid fast bacilli, WC1+(Sd(Bdelta TCR+ cells and less TGF-(Sb(B expression in comparison to controls.  B cells clustered intensely along the outer granuloma margins within vaccinated calves, with significantly more IFN-(Sd(B producing cells identified in the medullary regions of lymph nodes from BCG-vaccinated animals compared to unvaccinated controls.  This may be indicative of immune activation and surveillance in regions not directly associated with ongoing disease.  Lymph node evaluation using light microscopy and immunohistochemical markers is useful to assess the immune response and discriminate granulomas to determine vaccine efficacy and disease severity.
Descriptors:  cattle, infected with Mycobacterium bovis BCG, virulent Mycobacterium bovis, necrotic granulomas, lesion classification, histochemical markers, lymph note granulomas, dynamics of vaccine challenge, IFN-gamma, TGF-beta, type I procollagen, cell marker identification of T cells, B cells, macrophages and WCl+gamma delta TCR+ cells.

Johnston, A.M.  The 1901 Congress on Tuberculosis: John McFadyean and beyond.  Veterinary Microbiology.  2006; 112 (2/4): 347-368.  ISSN:  0378-1135.  Note:  Special issue:  S.J.More, More; J.D. Collins; E. Gormley; M. Good; R.A. Skuce; J.M. Pollock (editors).  Proceedings of the 4th International Conference on Mycobacterium bovis, Dublin, Ireland, 22-26 August 2005.
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description

NAL Call Number:  SF601.V44
Descriptors:  Mycobacterium bovis, cattle, humans, historical congress discussed, disease transmission, epidemiology, tuberculin testing.

Kaneene, J.B.; Miller, R.; Meyer, R.M.  Abattoir surveillance: the U.S. experience.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4): 273-282.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  Abattoir, or slaughter, surveillance has been an important component of bovine tuberculosis control and eradication programs in the U.S., and has adapted to changes in the livestock market from farm to table, and the threat of bovine tuberculosis from a wildlife reservoir.  The purpose of this overview was to describe the current goals of U.S. bovine tuberculosis slaughter surveillance, describe the elements of slaughter surveillance in the U.S., describe enhancements to the slaughter surveillance system, and discuss future challenges for the U.S. bovine tuberculosis surveillance program.  Government regulations and the scientific literature were examined to provide information for this paper.  The control and eradication of bovine tuberculosis in livestock falls to the United States Department of Agriculture and two agencies within the Department: the Food Safety and Inspection Service (FSIS) and the Animal and Plant Health Inspection Service (APHIS). FSIS conducts routine slaughter surveillance for disease or conditions that render carcasses unsuitable for human consumption, while APHIS is involved in antemortem bovine tuberculosis testing, and necropsy and investigation of bovine tuberculosis cases identified through slaughter surveillance or antemortem testing.  Results from the previous 5 years of surveillance are presented.  Enhancements have been added to the current surveillance system to improve its performance.  An incentive program has been used to increase the numbers of tissues submitted for laboratory examination, the state of Michigan is implementing electronic animal identification under a pilot program, and expansions to the current system are being developed to accommodate new livestock industries.  The success of these programs and challenges for the future are discussed.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control, disease control programs, disease outbreaks, disease transmission, meat inspection, disease surveillance, slaughter, slaughterhouses, zoonoses, humans, tuberculosis, health policy, agricultural policy, pathogen eradication, United States.

Kantor, I.N. de; Ritacco, V.  An update on bovine tuberculosis programmes in Latin American and Caribbean countries.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4): 110-119.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  Of the approximately 374 million cattle in Latin America and the Caribbean, 70% are held in areas where rates of Mycobacterium bovis infection in cattle are higher than 1%.  The remaining 30% are in countries where infection affects less than 1% of cattle, including 62 million in countries where bovine tuberculosis infection is virtually nil.  Measures for controlling bovine tuberculosis are partially or extensively applied in most of the countries in the Region.  These measures are based on test and slaughter, notification, post-mortem inspection and surveillance in slaughterhouses.  A coordinated production, standardization and quality control of purified protein derivatives is urgently required for use in control and eradication campaigns in order to assure reliability of reagents and comparability of data on tuberculin testing within the Region.  On the basis of information from Argentina, M. bovis is estimated to cause 2% of all human cases of tuberculosis in the Region. Slaughterhouse and dairy farms workers are most-frequently infected, with infection occurring via the respiratory tract. Various in vitro assays for the diagnosis of bovine tuberculosis have been developed and/or assessed in the Region, and DNA fingerprinting has been applied for a comprehensive understanding of the epidemiology of bovine tuberculosis at the local and regional level.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, disease control, disease control programs, quarantine, literature reviews, disease incidence, epidemiology, agricultural policy, culling animals, disease surveillance, disease diagnosis, analytical kits, DNA profiling, zoonoses, public health, tuberculosis, humans, pathogen eradication, Latin America, Caribbean.

Karls, R.  Tuberculosis in cattle: how to get the upper hand.  Veterinary Journal.  2006; 171 (2): 193-194.  ISSN: 1090-0233.  Note:  An editorial.  
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/623077/description#description
NAL Call Number:  SF601.V484
Descriptors:  cattle, humans, Mycobacterium bovis, Mycobacterium tuberculosis, zoonotic disease, disease control, vaccine development, tuberculosis, vaccination.

Katoch, R.C.; Mandeep Sharma; Kisthwaria, R.S.; Subhash Verma; Rajinder Kumar. Confirmation of pulmonary tuberculosis by isolation and by PCR-RFLP in a crossbred cow.  Indian Veterinary Journal.  2006; 83 (3): 338-339.  ISSN:  0019-6479
URL:  http://www.indvetjournal.com
NAL Call Number:  41.8 IN2
Descriptors:  crossbred cow, Mycobacterium tuberculosis, bovine tuberculosis, pulmonary disease, case study, Himachal Pradesh, India.

Kazwala, R.R.; Kusiluka, L.J.M.; Sinclair, K.; Sharp, J.M.; DAbstractorn, C.J.  The molecular epidemiology of Mycobacterium bovis infections in Tanzania.  Veterinary microbiology. 2006 Feb. 25; 112 (2-4): 201-210.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  A molecular epidemiological study to determine the zoonotic importance of bovine tuberculosis was carried out in Tanzania.  Specimens from human cases of tuberculosis as well as from slaughtered cattle were collected from regions with a high proportion of extrapulmonary tuberculosis.  In order to determine the similarity of strains from the two sources, molecular typing techniques, namely RFLP and spoligotyping, were used to determine the genetic profile of the strains involved.  The results of pTBN12 typing of M. bovis from cattle and man have shown a rather heterogeneous population of this species spread all over Tanzania, assuming that the present sample is representative.  There were 13 different pTBN12 RFLP types encountered.  The genetic relatedness between the pTBN12 RFLP patterns indicated a high degree of relatedness (86%) between the dominant pTBN12 genotypes existing in Tanzania.  There were 13 different spoligotypes found in this study, whose genetic relatedness was also high (79%).  DNA profiles were also confirmed by IS986 RFLP, which revealed that strains have 1-13 copies of IS986.  Geographically, there was overlap between pTBN12 RFLP and spoligotypes amongst strains isolated from various parts of Tanzania.  The diversity of the RFLP and spoligotype patterns observed in Tanzania probably reflects the extensive internal movements of cattle belonging to pastoralists.  The evidence of overlap between DNA fingerprints of M. bovis from cattle and man has once more highlighted a need for synergy of veterinary and medical policies in the control of tuberculosis in Tanzania and probably in other developing countries.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, microbial genetics, disease incidence, strains, zoonoses, humans, tuberculosis, strain differences, pathogen identification, genotype, restriction fragment length polymorphism, genetic markers, geographical distribution, wildlife vaccination programs, Tanzania.

Khan, M.Z.; Khan, A.  Basic facts of mastitis in dairy animals: a reviewPakistan Veterinary Journal.  2006; 26 (4): 204-208.  ISSN:  0253-8318
Descriptors:  buffalo, cattle, Corynebacterium, Escherichia coli, Mycobacterium, Mycobacterium tuberculosis, Mycoplasma, Pseudomonas, Staphylococcus, Staphylococcus aureus, Streptococcus, Streptococcus agalactiae, Streptococcus dysgalactiae, chemotherapy, milk constituents, milk contamination, Pakistan.

Kinne, J.; Johnson, B.; Jahans,K.L.; Smith, N.H.; Ul Haq, A.; Wernery, U.  Camel tuberculosis-a case report.  Tropical Animal Health and Production.  2006 Apr; 38 (3): 207-213.  ISSN:  0049-4747
URL:    http://dx.doi.org/10.1007/s11250-006-4366-8
NAL Call Number:  SF601 .T7
Descriptors:  dromedary camel, case report, Mycobacterium tuberculosis complex, tuberculosis, lungs, disease diagnosis, United Arab Emirates

Klerk, L. de; Michel, A.L.; Grobler, D.G.; Bengis, R.G.; Bush, M.; Kriek, N.P.J.; Hofmeyr, M.S.; Griffin, J.F.T.; MacKintosh, C.G.  An experimental intratonsilar infection model for bovine tuberculosis in African buffaloes, Syncerus caffer.  Onderstepoort Journal of Veterinary Research.  2006; 73 (4): 293-303.  ISSN:  0030-2465
Descriptors:  buffalo (Syncerus-caffer) cattle, high and low dose levels of Mycobacterium bovis, experimental infection, intratonsilar inoculation, vaccine evaluation, intradermal truberculin test, invitro modified interferon gamma assay, postmortem exam, lesion development assessed.

Kruuk, H.  Control of badgers and bovine TB.  Veterinary Record (London).  2006; 158 (13): 455.  ISSN:  0042-4900.  Note:  Correspondence.  
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  badgers (Meles meles), cattle, Mycobacterium bovis, disease, control, wildlife as a disease reservoir, UK. 

Lambert, W.; Gobena-Ameni; Manaye, K.; Yalemtsehay, Mekonnen.  Study on bovine tuberculosis in the Holeta dairy farm, Central Ethiopia.  Journal of Animal and Veterinary Advances.  2006; 5 (12): 1150-1154.  ISSN:  1680-5593
Descriptors:  dairy cattle, farm study, Mycobacterium bovis, bovine tuberculosis, zoonotic disease, control measures, retesting a herd after 2 years, recommend regular testing and removal of TB positive animals, Ethiopia.

Leslie, N.W.  Spread of bovine TB as a result of restocking.  Veterinary Record (London).  2006; 159 (12): 396.  ISSN:  0042-4900
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  cattle, disease transmission, movement of cattle to restock farms, Mycobacterium bovis, spread of disease.

Li, Jing Jing; Zhao,  De Ming; Xu,  Guang Xian; Zhou, Xiang Mei; Yin,  Xiao Min.  Cloning and expression of Mycobacterium bovis secreted protein MPB83 in Escherichia coliJournal of China Agricultural University.  2006; 11 (6): 19-22.  ISSN: 1007-4333.  Note:  In Chinese with an English summary.  
NAL Call Number:  S19.C58
Descriptors:  Mycobacterium bovis, cloning of the MPB83 gene, analysis of its expression, SDS-PAGE and western blotting technique, possible diagnostic tool.

Li, Rui Fang; Qin, Ai Jian; Xu, Jin Jun.  Preparation of the specific monoclonal antibody against bovine gamma -interferon and its properties.  Chinese Journal of Zoonoses.  2006; 22 (8): 755-758.  ISSN:  1002-2694.  Note:  In Chinese with an English summary.
Descriptors:  cattle, Mycobacterium bovis, monoclonial, antibody, fusion SP2/0cells and immunized mice spleen cells, immunogen on BALB/cmice, BovIFN-gamma 4A3 BovIFN-gamma4G5, use for surveillance and control of TB in milk cows.

Lilenbaum, W.; Fonseca, L. de S.  The use of ELISA as a complementary tool for bovine tuberculosis control in Brazil.  Brazilian Journal of Veterinary Research and Animal Science. 2006; 43 (2): 256-261.  ISSN:  1413-9596.  Note:  English with a Portuguese summary.  
Descriptors:  cattle, Mycobacterium bovis, control program, infected herds, lung lesions, culling animals, ELISA, serological testing, diagnostic tests, Rio de Janeiro, Brazil.

Livingstone, P.G.; Ryan, T.J.; Hancox, N.G.; Crews, K.B.; Bosson, M.A.J.; Knowles, G.J.E.; McCook, W. Regionalisation: a strategy that will assist with bovine tuberculosis control and facilitate trade.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4): 291-301.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  It is expected that the revised chapter on bovine tuberculosis in the Terrestrial Animal Health Code of the Office Internationale des Epizooties (OIE) will embrace regionalisation as a functional means of assisting countries, states or regions to meet the requirements for freedom from tuberculosis and to facilitate trade.  The benefits and applications of regionalisation, which comprises zoning and compartmentalisation, are discussed.  Regionalisation requires that a country's veterinary administration is able to implement transparent and auditable biosecurity measures that will ensure that the tuberculosis-free status of a subpopulation of cattle is maintained despite the presence of infection in another cattle subpopulation, or in other domestic or wild animal species.  Zoning, which requires cattle subpopulations to be separated by geographic boundaries, provides a practical basis whereby countries, states or regions, can progress towards freedom from tuberculosis, regardless of the source of infection for defined cattle subpopulations.  Compartmentalisation however, requires that husbandry or management practices will be used to prevent a tuberculosis-free cattle subpopulation from contacting inter-specific and intra-specific sources of infection.  This will be difficult to achieve except for specialised cases such as artificial breeding centers.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control, disease control programs, international trade, disease transmission, biosecurity, disease prevention, wild animals, animal diseases, tuberculosis, geographical distribution, animal husbandry, disease surveillance, wildlife, case studies, disease reservoirs, pathogen eradication, regionalization, New Zealand.

Lopes, L.B.; Cunha, A.P. da; Mota, R.A.; Leite, R.C.  Comparacao de duas tecnicas de tuberculinizacao em bufalos.  [Comparison of two tuberculin tests in buffaloes.]  Ciencia Animal Brasileira.  2006; 7 (2): 187-191.  ISSN:  1518-2797
Descriptors:  buffalo, 11 different herds, Mycobacterium bovis, diagnostic test, comparison study, single tuberculin test, comparative tuberculin test, mammalian antigen, combined mammalian and avian antigens, Brazil.

Macdonald, D.W.; Riordan, P.; Mathews, F.  Biological hurdles to the control of TB in cattle: a test of two hypotheses concerning wildlife to explain the failure of control.  Biological Conservation.  2006; 131 (2): 268-286.  ISSN:  0006-3207
URL:  http://www.sciencedirect.com/science/journal/00063207
NAL Call Number:  S900.B5
Descriptors:  badgers (Meles meles), wildlife as disease reservoirs, culling badgers, disease transmission, Mycobacterium bovis, bovine tuberculosis, control programs, disease surveillance, Britain, United Kingdom.

Mathews, Fiona; Macdonald, David W.; Taylor, G Michael; Gelling, Merryl; Norman, Rachel A.; Honess, Paul E.; Foster, Rebecca; Gower, Charlotte M.; Varley, Susan; Harris, Audrey; Palmer, Simonette; Hewinson, Glyn; Webster, Joanne P.   Bovine tuberculosis (Mycobacterium bovis) in British farmland wildlife: the importance to agriculture.   Proceedings of the Royal Society Biological Sciences Series B.  2006; 273 (1584): 357-365.   ISSN:  0962-8452
URL:
http://journals.royalsociety.org/home/main.mpx
NAL Call Number:  501 L848
Descriptors:  British cattle herd, cattle diseases, Mycobacterium bovis, wildlife disease reservoirs, bank voles, badgers, pathogen levels, probably not the most important source of disease, economic costs.

Meade, K.G.; Gormley, E.; Park, S.D.E.; Fitzsimons, T.; Rosa, G.J.M.; Costello, E.; Keane, J.; Coussens, P.M.; MacHugh, D.E.  Gene expression profiling of peripheral blood mononuclear cells (PBMC) from Mycobacterium bovis infected cattle after in vitro antigenic stimulation with purified protein derivative of tuberculin (PPD).  Veterinary Immunology and Immunopathology.  2006; 113 (1/2): 73-89.  ISSN:  0165-2427
URL:  http://www.sciencedirect.com/science/journal/01652427
NAL Call Number:  SF757.2.V38
Descriptors:  cattle, Mycobacterium bovis, bovine tuberculosis, immunity reactions, immunological reactions, mRNA, peripheral blood mononuclear cells, purified protein derivative, PPD.

Michel, A.L.; Bengis, R.G.; Keet, D.F.; Hofmeyr, M.; de Klerk, L.M.; Cross, P.C.; Jolles, A.E.; Cooper, D.; Whyte, I.J.; Buss, P.  Wildlife tuberculosis in South African conservation areas: implications and challenges.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4): 91-100.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  Tuberculosis, caused by Mycobacterium bovis, was first diagnosed in African buffalo in South Africa's Kruger National Park in 1990.  Over the past 15 years the disease has spread northwards leaving only the most northern buffalo herds unaffected.  Evidence suggests that 10 other small and large mammalian species, including large predators, are spillover hosts.  Wildlife tuberculosis has also been diagnosed in several adjacent private game reserves and in the Hluhluwe-iMfolozi Park, the third largest game reserve in South Africa.  The tuberculosis epidemic has a number of implications, for which the full effect of some might only be seen in the long-term.  Potential negative long-term effects on the population dynamics of certain social animal species and the direct threat for the survival of endangered species pose particular problems for wildlife conservationists.  On the other hand, the risk of spillover infection to neighboring communal cattle raises concerns about human health at the wildlife-livestock-human interface, not only along the western boundary of Kruger National Park, but also with regards to the joint development of the Greater Limpopo Trans-frontier Conservation Area with Zimbabwe and Mozambique.  From an economic point of view, wildlife tuberculosis has resulted in national and international trade restrictions for affected species.  The lack of diagnostic tools for most species and the absence of an effective vaccine make it currently impossible to contain and control this disease within an infected free-ranging ecosystem.  Veterinary researchers and policy-makers have recognized the need to intensify research on this disease and the need to develop tools for control, initially targeting buffalo and lion.
Descriptors:  African buffalo, (Syncerus caffer), wild animals, Mycobacterium bovis, animal pathogenic bacteria, tuberculosis, wildlife, animal diseases, conservation areas, disease outbreaks, alternative hosts, disease transmission, endangered species, literature reviews, lions (Panthera leo), disease control, disease reservoirs, South Africa, Zimbabwe, Mozambique.

Miller, R.A.; Kaneene, J.B.  Evaluation of historical factors influencing the occurrence and distribution of Mycobacterium bovis infection among wildlife in Michigan.  American Journal of Veterinary Research.  2006 Apr; 67 (4): 604-615.  ISSN: 0002-9645.
NAL Call Number:  41.8 Am3A
Descriptors:  cattle, white tailed deer, Mycobacterium bovis, bovine tuberculosis, disease reservoirs, spatial distribution, disease outbreaks, Odocoileus virginianus, temporal variation, risk factors, disease prevalence, wildlife livestock relations, population density, population size, environmental factors, animal husbandry, wildlife management, ribotypes, zoonoses, Michigan.

Mitchell, A.  Bovine TB: modelling and predicting its distribution in GB using CTS data.  GVJ-Government Veterinary Journal.  2006; 16 (1): 46-52.  ISSN:  0269-5545
URL:  http://www.defra.gov.uk/gvs/publications/gvj/pdf/gvj-vol1701.pdf (PDF | 731KB)
Descriptors:  cattle, Mycobacterium bovis, modeling of disease distribution, zoonotic infections, Great Britain.  

Mobius, P.; Lentzsch, P.; Moser, I.; Naumann, L.; Martin, G.; Kohler, H.  Comparative macrorestriction and RFLP analysis of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuis isolates from man, pig, and cattle.  Veterinary Microbiology.  2006 Oct 31; 117 (2-4): 284-291.  ISSN:  0378-1135
URL:  http://dx.doi.org/10.1016/j.vetmic.2006.05.005
NAL Call Number:  SF601.V44
Abstract:  In Germany, tuberculous lesions in slaughtered pigs due to infection with members of the Mycobacterium avium complex are increasingly reported.  Contaminated food originating from pig or other livestock is discussed as potential source of human infection.  M. avium isolates from man (n = 45), pig (n = 29), and cattle (n = 13) were characterised by restriction fragment length polymorphism (RFLP) with respect to insertion sequences IS1245 and IS901 as well as by XbaI-based pulsed-field gel electrophoresis (PFGE) and the results were compared by computer cluster correlation analysis, to determine potential sources of infection in man.  By PCR, 55% of animal isolates was identified as M. avium subsp. avium, and 45% as M. a. hominissuis.  All human isolates belonged to M. a. hominissuis.  IS1245-RFLP and PFGE resulted in two distinct main groupings reflecting the two subspecies, and dividing the isolates into several subgroups.  Animal isolates of M. a. hominissuis were widely distributed within the subgroups of human isolates.  M. a. avium isolates, further discriminated by IS901-RFLP, formed host-associated subgroups for animals.  Comparison of RFLP patterns with those of PFGE resulted in different subgroups as well as different pairs of isolates with high similarities.  Only two isolates exhibited identical patterns by both methods.  In general, results of both methods support the possibility that M. a. hominissuis isolates from livestock represent a source of infection for man, probably by common environmental reservoirs.  There was no evidence of human infections caused by M. a. avium in Germany.
Descriptors:  pigs, humans, Mycobacterium avium avium, Mycobacterium avium hominissuis, bacterial isolates, zoonotic tb strains, food contamination, RFLP characterization, Germany.

Moda, G. Non-technical constraints to eradication: the Italian experience.  Veterinary Microbiology. 2006 Feb. 25; 112 (2-4): 253-258.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44

Abstract:  Although technical constraints to eradication of bovine tuberculosis are well-recognized, non-technical constraints can also delay progress towards eradication, leading to inefficiency and increased programme costs.  This paper seeks to analyze the main non-technical constraints that can interfere with the successful implementation of tuberculosis eradication plans, based on experiences from an area of high tuberculosis prevalence in Regione Piemonte, Italy.  The main social and economic constraints faced in the past 20 years are reviewed, including a social reluctance to recognize the importance of seeking eradication as the goal of disease control, effective communication of technical issues, the training and the organization of veterinary services, the relationship between the regional authority and farmers and their representatives, and data management and epidemiological reporting.  The paper analyses and discusses the solutions that were applied in Regione Piemonte and the benefits that were obtained.  Tuberculosis eradication plans are one of the most difficult tasks of the Veterinary Animal Health Services, and non-technical constraints must be considered when progress towards eradication is less than expected.  Organizational and managerial resources can help to overcome social or economic obstacles, provided the veterinary profession is willing to address technical, but also non-technical, constraints to eradication.

Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control, disease control programs, disease prevalence, pathogen eradication, economic analysis, economic costs, social behavior, social barriers, veterinarians, social environment, Italy.

Monies, R.J.  Tuberculous pneumonia and BVD in housed calves.  GVJ-Government Veterinary Journal.  2006; 16 (1): 81-86.  ISSN:  0269-5545
URL:  http://www.defra.gov.uk/gvs/publications/gvj/pdf/gvj-vol1701.pdf (PDF | 731KB)
Descriptors:  calves, cattle, disease levels, bovine diarrhea virus, BVD, cattle, Mycobacterium bovis, postmortem inspections, autopsy reports, clinical picture, mucosal diseases, multiple infections, death rates, United Kingdom.

More, S.J.; Collins, J.D.; Gormley, E.; Good, M.; Skuce, R.A.; Pollock, J.M.  Proceedings of the 4th International Conference on Mycobacterium bovis, Dublin, Ireland, 22-26 August 2005.  Veterinary Microbiology.  2006; 112 (2/4): 89-391.  ISSN:  0378-1135.  Note:  Special issue:  S.J. More; J.D. Collins; E. Gormley; M. Good; R.A. Skuce;  J.M. Pollock (editors).  Proceedings of the 4th International Conference on Mycobacterium bovis, Dublin, Ireland, 22-26 August 2005.
URL:  http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number:  SF601.V44
Descriptors:  humans, livestock domestic animals, cattle, wild animals, Mycobacterium bovis, diagnosis, epidemiology, zoonotic disease prevalence, pathogenesis, diagnosis and control, vaccination, animal reservoirs, vaccine development.

More, S.J.; Collins, J.D.; Gormley, E.; Good, M.; Skuce, R.A.; Pollock, J.M.  4th International Conference on Mycobacterium bovis: workshop reports.  Veterinary Microbiology.  2006; 112 (2/4): 383-391.  ISSN:  0378-1135.  Note:  Special issue:  S.J. More; J.D. Collins; E. Gormley; M. Good; R.A. Skuce;  J.M. Pollock (editors).  Proceedings of the 4th International Conference on Mycobacterium bovis, Dublin, Ireland, 22-26 August 2005.
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description

NAL Call Number:  SF601.V44
Descriptors:  conference workshop reports, policy, strategy, Mycobacterium bovis, disease control, disease eradication programs, diagnosis, molecular epidemiology, wild animals as disease reservoirs, vaccines, vaccination of animals, cattle, livestock.

More, S.J.; Good, M.  The tuberculosis eradication programme in Ireland: a review of scientific and policy advances since 1988.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4): 239-251.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number: SF601.V44
Abstract:   A national programme to eradicate bovine tuberculosis commenced in Ireland in 1954.  During the last 15-20 years, research has been conducted to address gaps in knowledge of disease epidemiology, to objectively evaluate alternative strategy options, and to critically assess the implementation of disease control strategies.  This paper provides a review of scientific and policy advances in Ireland since 1988, relevant to the tuberculosis eradication programme in Ireland.  There have been substantial advances in knowledge of aspects of disease epidemiology, relating to cattle-to-cattle transmission, the role of wildlife, transmission of infection from wildlife and methods to minimise wildlife-to-cattle transmission.  Further, scientific advances have been made both in the detection and management of infected herds.  With respect to policy, the paper describes current policy and policy advances in both the detection and management of infected herds, as well as current strategies to prevent herd breakdowns.  The Irish programme is a useful example of science-informed policy in a national context.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, disease control, disease control programs, disease surveillance, disease outbreaks, culling animals, wildlife, animal diseases, tuberculosis, disease reservoirs, diagnosis, disease transmission, pathogen identification, pathogen eradication, literature reviews, agricultural policy, Irish Republic.

Mores, N.; Amaral, A.L.; Ventura, L.; Silva, R.A.M.; Silva, V.S.; Barioni-Junior, W.  Comparacao entre metodos de tuberculinizacao no diagnostico da infeccao por agentes do complexo Mycobacterium avium ou M. bovis em suinos.  [Comparative study of methods of tuberculin skin test with the avium and bovine tuberculin in the diagnosis of the infection by agents of the Mycobacterium avium-complex or M. bovis in swine.]  Arquivo Brasileiro de Medicina Veterinaria e Zootecnia.  2006; 58 (5): 708-717.  ISSN:  0102-0935.  Note:  In Portuguese with an English summary.  
NAL Call Number:  SF604.A76
Descriptors:  hogs, swine, naturally and experimentally infected hogs, tuberculin skin test with avian and bovine PPD, detection of pathogen, skin readings compared to gross lesions and histological changes in lymph nodes, diameter of reaction.

Mustafa, A.S.; Skeiky, Y.A.; Al Attiyah, R.; Alderson, M.R.; Hewinson, R.G.; Vordermeier, H.M.  Immunogenicity of Mycobacterium tuberculosis antigens in Mycobacterium bovis BCG-vaccinated and M. bovis-infected cattle.  Infection and immunity (IAI).  2006 Aug.; 74 (8): 4566-4572.  ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  The development of novel vaccine strategies supplementing Mycobacterium bovis BCG (BCG) constitutes an urgent research challenge.  To identify potential subunit vaccine candidates, we have tested a series of eight recently identified Mycobacterium tuberculosis antigens in M. bovis-infected and BCG-vaccinated cattle.  These antigens were characterized on the basis of their ability to induce in vitro gamma interferon responses in infected or BCG-vaccinated calves.  We were able to establish a hierarchy of these antigens based on how frequently they were recognized in both groups of animals.  In particular, we were able to prioritize frequently recognized proteins like Rv0287, Rv1174, and Rv1196 for future evaluation as subunit vaccines to be used in BCG-protein heterologous prime-boost vaccination scenarios.  In addition, the antigen most dominantly recognized in M. bovis-infected cattle in this study, Rv3616c, was significantly less frequently recognized by BCG vaccinees and could be a target to improve BCG, for example, by increasing its secretion, in a recombinant BCG vaccine.
Descriptors:  cattle, vaccines, subunit vaccine candidates, eight Mycobacterium tuberculosis antigens, Mycobacterium bovis-infected and BCG-vaccinated cattle, Rv3616c antigen.

Nassar, A.F.de C.; Roxo, E.; Portugal, M.A.da S.C.  Revisao: tuberculose genital em bovinos e bubalinos.  [Review: genital tuberculosis in cattle and water buffaloes.] Revista de Educacao Continuada do CRMV-SP.  2005; 8 (2): 135-144.  ISSN:  1516-3326.  Note:  In Portuguese with English and Spanish summaries.  
Descriptors:  cattle, water buffalo, Mycobacterium bovis, genital tuberculosis, endometritis, incidence over 30 years, economic impact, zoonotic disease public health concern, contaminated raw milk and cheese, bovine mastitis, complications, disease prevalence; epidemiology, Sao Paulo, Brazil.

Nishath Latheef; Ganesan, P.I.  Haematological and biochemical parameters in tuberculin reactor and non reactor cattle.  Indian Veterinary Journal.  2006; 83 (8): 918-919.  ISSN:  0019-6479
URL:  www.indvetjournal.com
NAL Call Number:  41.8 IN2
Descriptors:  cattle, Mycobacterium bovis, intradermal tuberculin test reactions, description of positive reaction, hematology of test reactors, blood cell counts, hemoglobin, hematocrit, serum biochemistry, clinical responses.

Nishi, J.S.; Shury, T.; Elkin, B.T.  Wildlife reservoirs for bovine tuberculosis (Mycobacterium bovis) in Canada: strategies for management and research.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4) 325-338.  ISSN: 0378-1135. Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44

Abstract:  In Canada, there are two known regional foci where wildlife populations are infected with bovine tuberculosis (Mycobacterium bovis) and considered to be disease reservoirs.  Free-ranging populations of wood bison (Bison bison athabascae) in and around Wood Buffalo National Park (WBNP) and wapiti (Cervus elaphus manitobensis) in and around Riding Mountain National Park (RMNP) are infected with bovine tuberculosis.  In this paper, we provide an overview of these diseased wild ungulate populations and the complexities of attempting to manage issues relating to bovine tuberculosis in and around protected areas.  We do not describe the quantitative science and epidemiological data in detail from these case histories, but instead compare and contrast these two cases from a broader perspective.  This is achieved by reviewing the context and process by which a diverse group of stakeholders engage and develop strategies to address the controversial problems that diseased wildlife populations often present.  We suggest that understanding the factors that drive the strategic-level management processes is equally important for addressing a wildlife disease problem as the tactical-level issues, such as design and implementation of technically sound field research and management programs.  Understanding the experiences within the WBNP and RMNP areas, particularly the strategies that have failed or succeeded, may prove useful to understanding and improving management approaches when wildlife are infected with M. bovis.  Applying this understanding is consistent with the principles of adaptive management in which we learn from previous experiences to develop better strategies for the future.
Descriptors:  cattle, food animals, Mycobacterium bovis, wood bison (Bison bison athabascae), Wood Buffalo National Park, wapiti (Cervus elaphus manitobensis), Riding Mountain National Park, diseased wild ungulate populations, disease management issues in protected areas, how to approach strategic level management processes, disease vectors, disease transmission, control programs, literature reviews, wildlife management, wild animals, wildlife, animal diseases, tuberculosis, alternative hosts, disease outbreaks, disease transmission, conservation areas, case studies, disease control programs, disease reservoirs, Alberta, Canada.

O'Brien, D.J.; Schmitt, S.M.; Fitzgerald, S.D.; Berry, D.E.; Hickling, G.J. Managing the wildlife reservoir of Mycobacterium bovis: The Michigan, USA, experience.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4) 313-323.  ISSN: 0378-1135. Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  Historical, social and economic factors combined to provide a focus where bovine tuberculosis has become established in free-ranging wildlife in northeastern lower Michigan. White-tailed deer, the primary reservoir and maintenance host of tuberculosis, are highly valued by the public, and particularly hunters, for cultural and economic reasons.  Since 1995, significant progress has been made in defining and reducing the reservoir of tuberculosis in deer.  As yet, no other wildlife species has been shown to play an epidemiologically important role in the disease cycle.  The importance of deer and deer hunting to Michigan has uniquely shaped tuberculosis control policies, and poses ongoing challenges as wildlife managers strive to maintain momentum for broad control strategies, and develop focused strategies that are publicly acceptable.  Even if momentum and funding can be maintained, tuberculosis will likely continue to be present for a decade or longer.  Thus, cattle producers waiting for tuberculosis to be eradicated from wildlife to eliminate risks to their herds and markets face disappointment for the foreseeable future.  Such unrealistic expectations also place Michigan's federal tuberculosis accreditation status at perpetual risk.  Accredited free status is unlikely to be regained without accompanying changes in cattle management.  In Michigan, management of tuberculosis has clearly demonstrated that social issues and public approval are likely to be the critical limiting factors in control.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, wildlife management, deer, wild animals, wildlife, tuberculosis, alternative hosts, disease outbreaks, disease transmission, case studies, social barriers, public opinions, sport hunting, disease control programs, disease control programs, disease reservoirs, Michigan.

Olea-Popelka, F.; Butler, D.; Lavin, D.; McGrath, G.; O'Keeffe, J.; Kelton, D.; Berke, O.; More, S.; Martin, W.  A case study of bovine tuberculosis in an area of County Donegal, Ireland.  Irish Veterinary Journal.  2006; 59 (12): 683-690.  ISSN:  0368-0762
URL:  www.veterinary-ireland.org
Descriptors:  cattle, badgers, disease level, herd to herd transmission, bovine tuberculosis, Mycoabacterium bovis, animal disease control-programs, Eire, Irish Republic.

Olea-Popelka, F.J.; Phelan,.J.; White, P.W.; McGrath, G; Collins, J.D.; O'.Keeffe, J.; Duggan, M.; Collins, D.M.; Kelton,-DF; Berke, O.  Quantifying badger exposure and the risk of bovine tuberculosis for cattle herds in county Kilkenny, Ireland.  Preventive Veterinary Medicine.  2006 July 17; 75 (1-2): 34-46.  ISSN1:  0167-5877
URL:  http://dx.doi.org/10.1016/j.prevetmed.2006.01.014
NAL Call Number:  SF601.P7
Descriptors:  cattle, cattle diseases, bovine tuberculosis, Mycobacterium bovis, epidemiological studies, disease transmission, wildlife, disease reservoirs, badgers, Meles meles, risk assessment, wildlife livestock relations, pastures,  cattle grazing,  cattle housing, herd health, disease incidence, quantitative analysis, Irish Republic.  

Oloya, J.; Opuda-Asibo, J.; Djonne, B.; Muma, J.B.; Matope, G.; Kazwala, R.; Skjerve, E.  Responses to tuberculin among Zebu cattle in the transhumance regions of Karamoja and Nakasongola district of Uganda.  Tropical Animal Health and Production.  2006 May; 38 (4): 275-283.  .  ISSN: 0049-4747
URL: http://dx.doi.org/10.1007/s11250-006-4322-7
NAL Call Number:  SF601.T7
Descriptors:  zebu, seroprevalence, bovine tuberculosis, risk factors, drinking water, dry season, Mycobacterium bovis, transhumance regions, skin tests, zoonoses, Uganda.  

Palmer, M.V.; Waters, W.R.  Advances in bovine tuberculosis diagnosis and pathogenesis: what policy makers need to know.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4) 181-190.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  The mainstay of tuberculosis diagnosis in cattle and deer has been the tuberculin skin test.  Recent advances have allowed the incorporation of blood based assays to the diagnostic arsenal for both cattle and deer.  Use of defined and specific antigens has allowed for improved specificity of cell mediated assays in both cattle and deer and advances in antibody tests for tuberculosis have potential for use in free-ranging and captive cervid populations.  Combined use of blood-based assays with skin testing will require further understanding of the effect of skin testing on the accuracy of blood based assays.  Models of experimental infection of cattle have allowed for increased understanding of natural disease pathogenesis.  Differences likely exist; however, between cattle and deer in both disease distribution and primary route of inoculation in naturally infected animals.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease diagnosis, pathogenesis, disease course, agricultural policy, health policy, zoonoses, diagnostic techniques, deer, wild animals, animal diseases, tuberculosis, disease transmission, epidemiology, interferons, tuberculin, bacterial antigens.

Palmer, M.V.; Waters, W.R.; Thacker, T.C.; Greenwald, R.; Esfandiari, J.; Lyashchenk, K.P.  Effects of different tuberculin skin-testing regimens on gamma interferon and antibody responses in cattle experimentally infected with Mycobacterium bovis.  Clinical and Vaccine Immunology.  2006; 13 (3): 387-394.  ISSN:  1556-6811
URL:  http://cvi.asm.org/
NAL Call Number:  RB46.5
Descriptors:  Holstein calves, experimental infection, Mycobacterium bovis, whole blood cellular immunoassay, bovine game interferon, INF gamma, comparative cervical test, caudal fold test, timing of testing may affect results.

Pavlik, I.  The experience of new European Union Member States concerning the control of bovine tuberculosis.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4): 221-230.  ISSN: 0378-1135. Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  On 1 May 2004, 10 new States joined the European Union, including Cyprus (CY), the Czech Republic (CR), Estonia (ES), Hungary (HU), Latvia (LA), Lithuania (LI), Malta (MA), Poland (PO), Slovakia (SK), and Slovenia (SN).  Using OIE and published data, this paper summarizes the status of bovine and human tuberculosis in animals in these countries between 1996 and 2003.  National control programmes against bovine tuberculosis in cattle have been successful: the current herd incidence of this disease in cattle is currently lower than 0.2%, so all countries meet the OIE requirements for freedom from the disease.  Furthermore, two countries have already been officially declared bovine tuberculosis-free EU States: the CR on 31 March 2004 (European Commission Decision No. 2004/320/EC) and SK on 4 March 2005 (Commission Decision No. 2005/179/EC).  The last outbreak of bovine tuberculosis was diagnosed in cattle in CY (1928), ES (1986), LA (1989), SK (1993), CR (1995), and MA (2001).  However, several issues of concern remain including the potential existence of a wildlife reservoir, the presence of Mycobacterium bovis, M. caprae, and other members of the M. tuberculosis complex (particularly M. tuberculosis or M. microti) in imported domestic or wild animals, and the potential for delayed detection of bovine tuberculosis in those States where annual tuberculin testing is no longer performed on cattle older than 24 months.
Descriptors:  cattle, Mycobacterium bovis, Mycobacterium bovis, Mycobacterium caprae, members of the Mycobacterium tuberculosis complex (particularly Mycobacterium tuberculosis, ycobacterium microti), animal pathogenic bacteria, bovine tuberculosis, disease control, disease control programs, humans, tuberculosis, zoonoses, disease incidence, herd health, disease outbreaks, wildlife, animal diseases, disease diagnosis, disease surveillance, disease reservoirs, European Union.

Pereira-Suarez, A.L.; Estrada-Chavez, C.; Arriaga-Diaz, C.; Espinosa-Cueto, P.; Mancilla, R.  Coexpression of NRAMP1, iNOS, and nitrotyrosine in bovine tuberculosis.  Veterinary Pathology.  2006; 43 (5): 709-717.  ISSN:  0300-9858
URL:  http://www.acvp.org
NAL Call Number:  41.8 P27
Abstract:  In murine models the inducible nitric oxide synthase (iNOS) and the natural resistance associated macrophage protein (NRAMP1) play major roles in host defence against mycobacteria.  iNOS regulates nitric oxide (NO) production, which is noxious for ingested mycobacteria, and NRAMP1 displays pleiotropic antimicrobial effects, including upregulation of iNOS expression.  Little is known about the role of these molecules in bovine tuberculosis (TB).  In this work we demonstrate by Western blot a high expression of NRAMP1 in peripheral blood mononuclear cells (PBMCs), alveolar macrophages (obtained by bronchioalveolar lavage), and lymph node granulomas from 8 Holstein-Freisian cattle with autopsy-proven bovine TB.  Immunohistochemistry revealed the abundant expression of NRAMP1 and iNOS in lymph node and lung granulomas.  Immunoreactivity was abundant in the cytoplasm of many epithelioid macrophages and multinucleated giant cells of the Langhans type.  A striking accumulation of nitrotyrosine (NT), an indicator of iNOS activity and local NO production, was observed in granuloma cells, particularly in multinucleated Langhans cells.  This study shows that the expression of NRAMP1 and iNOS is costimulated in granulomas, which are protective T-cell reactions against mycobacteria..
Descriptors:  Holstein-Freisian cattle, murine model, lymph node granulomas, T cells, nitric oxide synthase; nitrotyrosine Mycobacterium bovis.

Perrin, G.; Heraud, J.L.  Patologie dei piccoli ruminanti la diagnosi della tubercolosi nei caprini.  [Diagnosis of tuberculosis in goats.]  Summa, Animali da Reddito.  2006; 1 (2): 45-48. ISSN:  1125-6745.  Note:  In Italian.
Descriptors:  goats, diagnosis of TB, Mycobacterium bovis, disease surveillance, Italy.

Pfeiffer, D.U.  Communicating risk and uncertainty in relation to development and implementation of disease control policies.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4) 259-264.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  Scientific evidence is one of the key factors to be considered in the development of disease control policies.  It is generated using investigations into cause-effect relationships, which usually produce results that are associated with a varying degree of uncertainty.  Experience has shown that taking account of these uncertainties can become a formidable challenge for policy makers when devising the strategies and when communicating them to stakeholders.  The situation has been further complicated by a reduction in public trust in scientific evidence.  It is now recognized that this challenge cannot be managed by simply providing more information, but it is also necessary to consider the influence that variation in risk perception amongst stakeholders has on their response to and commitment towards the policies.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control programs, disease prevalence, risk assessment, agricultural policy, health policy, communication human, public opinion, risk communication, consumer information, scientific evidence.

Proano-Perez, Freddy; Rigouts, Leen; Brandt, Jef; Dorny, Pierre; Ron, Jorge; Chavez, Maria Augusta; Rodriguez, Richar; Fissette, Krista; Van Aerde, Anita; Portaels, Francoise; Benitez-Ortiz, Washington.  Preliminary observations on Mycobacterium ssp in dairy cattle in EcuadorAmerican Journal of Tropical Medicine and Hygiene.  2006; 75(2): 318-323.
URL:  www.ajtmh.org
Descriptors:  bovine tuberculosis, dairy cattle production, 1,012 cattle, 59 farms, tuberculin test, comparative tuberculin test, slaughter house tissue, Mycobacterium bovis, effect of dairy herd size, Mejia canton, Ecuador.

Proud, A.J. Some lessons from the history of the eradication of bovine tuberculosis in Great Britain.  GVJ-Government Veterinary Journal.  2006; 16 (1): 11-18.  ISSN:  0269-5545
URL:  http://www.defra.gov.uk/gvs/publications/gvj/pdf/gvj-vol1701.pdf (PDF | 731KB)
Descriptors:  cattle. Mycobacterium bovis, history of eradication programs, lessons learned, disease distribution, zoonotic infections, Great Britain.  

Radunz, B.  Surveillance and risk management during the latter stages of eradication: experiences from Australia.  Veterinary Microbiology.  2006 Feb 25;  112(2-4): 283-290.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description

NAL Call Number:  SF601.V44
Abstract:  The paper reviews the eradication of bovine tuberculosis from Australia with special reference to surveillance and managing the risk of animals exposed to tuberculosis infected animals during the latter stages of eradication.  The successful eradication was based on a sound technical program with strong industry and government support.  The model of joint industry and government funding and decision-making first used during the brucellosis and tuberculosis eradication campaign (BTEC) has been successfully incorporated within subsequent livestock disease control programs in Australia.  An overview of the history of tuberculosis eradication in Australia provides a background to the surveillance approach.  Australia was fortunate that there were no wildlife reservoir hosts.  Feral animal reservoir hosts were removed during the eradication program.  Surveillance to detect rare diseases is recognized to be statistically challenging with high resource requirements.  Australian veterinary authorities have a high level of confidence that the combination of increasing sensitivity of abattoir surveillance systems by the submission of all granulomas detected at slaughter with increasing risk management of animals exposed to tuberculosis infected animals during the final stages of eradication provides a high level of assurance that Mycobacterium bovis has been eradicated.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control programs, disease outbreaks, disease transmission, risk management, disease surveillance, decision making, agricultural history, wildlife, animal diseases, tuberculosis, disease reservoirs, slaughterhouses, meat inspection, pathogen eradication, culling animals, Australia

Ramirez-Casillas, I.C.; Santillan-Flores, M.A.; Arellano-Reynoso, B.; Morales-Alvarez, F.; Tenorio-Gutierrez,V.R.  Detection of Mycobacterium bovis nucleotide sequences from nasal mucus of experimentally inoculated goats.  Veterinaria Mexico.  2006; 37 (2): 191-196.  ISSN:  0301-5092.  Note:  In English and Spanish.
URL:  http://www.medigraphic.com/veterinariamexico/
NAL Call Number:  SF604.V485
Descriptors:  goats, fast reliable molecular method for Mycobacterium bovis, field application, M-PCR technique, detecting bacterial pathogen DNA in mucus, experimental infection, experimental transmission, immunity reactions, immunological reactions.

Reviriego-Gordejo, F.J.; Vermeersch, J.P.  Towards eradication of bovine tuberculosis in the European Union.  An update on bovine tuberculosis programmes in Latin American and Caribbean countries.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4): 101-109.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description

NAL Call Number:  SF601.V44
Abstract:  This paper reviews the developments and progress towards eradication of bovine tuberculosis in the European Union (EU).  A historical view of the EU legislation aimed at mainly approximating provisions on intra-community in cattle trade explains the present EU policies.  The variety of cattle breeding systems and environmental conditions in the EU leads to different epidemiological situations.  The current situation of bovine tuberculosis in the EU Member States is summarized, and current policy in the EU is outlined.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, international trade, disease control, disease control programs, quarantine, literature reviews, European Union, epidemiology, agricultural policy, pathogen eradication, Europe.

Reynolds, D.  TB policy developments.  GVJ-Government Veterinary Journal.  2006; 16 (1): 5-10.  ISSN:  0269-5545
URL:  http://www.defra.gov.uk/gvs/publications/gvj/pdf/gvj-vol1701.pdf (PDF | 731KB)
Descriptors:  cattle. Mycobacterium bovis, badgers (Meles meles), eradication and control programs, lessons learned, disease distribution, zoonotic infections, UK.  

Reynolds, D.  A review of tuberculosis science and policy in Great Britain.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4) 119-126.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description

NAL Call Number:  SF601.V44
Abstract:  Bovine tuberculosis is one of the most complex animal health problems that the farming industry in Great Britain faces today.  In leading and facilitating the changes to policy required to reverse the long-term upward trend in the disease, Government is heavily reliant on evidence emerging from its wide-ranging bovine tuberculosis research programme.  The paper outlines development of policy in Great Britain and its relationship to research findings.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, disease control, disease control programs, literature reviews, disease incidence, disease outbreaks, agricultural research, information sources, Great Britain.

Rishendra Verma; Samir Das.  Zoonotic tuberculosis due to Mycobacterium bovis in India.  Intas Polivet.  2006; 7 (2): 227-235.  ISSN:  0972-1738 
Descriptors:  zoonotic tuberculosis, Mycobacterium bovis, Mycobacterium tuberculosis, economic losses, humans, animals, wildlife, diagnosis, clinical picture, antiobiotic treatment, disease surveillance, zoonotic infections, India.

Romero, B.; Bezos, J.; Alvarez, J.; Aranaz, A.; Juan, L. de; Lozano, F.; Mateos, A.; Dominguez, L.; Travnicek, M.  Bovinna tuberkuloza v EU - pritomnost a buducnost.  [Bovine tuberculosis in EU - the presence and future.]  Slovensky Veterinarsky Casopis.  2006; 31 (3): 165-168.  ISSN:  1335-0099.  Note:  In Slovakian.  
Descriptors:  cattle, Mycobacterium bovis, Common Market, EC; EEC; European Communities, European Economic Communities. 

Romero-Tejeda, Aurora; Arriaga-Diaz, Camila; Guevara-Vivero, Jesus; Garcia-Salazar, Jose Alfredo; Torres-Leon, Ruben Arturo; Estrada-Chavez, Ciro.  Confirmacion de la excrecion de Mycobacterium bovis en exudados nasales mediante PCR anidada en un hato lechero.  [Confirmation of Mycobacterium bovis excretion in nasal exudates using nested PCR in a dairy cattle herd.]  Veterinaria Mexico. 2006; 37(1): 137-143.  ISSN:  0301-5092.  Note:  In Spanish.  
NAL Call Number:  SF604.V485
Descriptors:  dairy cattle, disease transmission, Mycobacterium bovis, respiratory excretion of bacteria and relationship with immune response, nasal exudates analyzed, nested PCR, IFN gamma.

Rosseels, Valerie; Marche, Sylvie; Roupie,Virginie; Govaerts, Marc; Godfroid, Jacques; Walravens, Karl; Huygen, Kris.  Members of the 30- to 32-kilodalton mycolyl transferase family (Ag85) from culture filtrate of Mycobacterium avium subsp. paratuberculosis are immunodominant Th1-type antigens recognized early upon infection in mice and cattle.  Infection and Immunity.  2006 Jan; 74 (1): 202-212.  ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  The characterization of protective antigens is essential for the development of an effective, subunit-based vaccine against paratuberculosis.  Surface-exposed and secreted antigens, present abundantly in mycobacterial culture filtrate (CF), are among the well-known protective antigens of Mycobacterium tuberculosis and Mycobacterium bovis.  Culture filtrate, prepared from Mycobacterium avium subsp. paratuberculosis ATCC 19698 grown as a surface pellicle on synthetic Sauton medium, was strongly and early recognized in experimentally infected B6 bg/bg beige mice and cattle, as indicated by elevated spleen cell gamma interferon (IFN-[gamma]) secretion and lympho-proliferative responses of peripheral blood mononuclear cells, respectively.  Strong proliferative and ex vivo IFN-[gamma] responses against antigen 85 (Ag85) complex (a major protein component from M. bovis BCG culture filtrate) could be detected in cattle as early as 10 weeks after oral M. avium subsp. paratuberculosis infection.  Synthetic peptides from the Ag85A and Ag85B components of this complex were strongly recognized, whereas T-cell responses were weaker against peptides from the Ag85C protein.  A promiscuous T-cell epitope spanning amino acids 145 to 162 of Ag85B (identical sequence in M. bovis and M. avium subsp. paratuberculosis) was identified in experimentally infected cattle.  Finally, young calves, born from cows with confirmed paratuberculosis, demonstrated proliferative responses to purified, recombinant Ag85A and Ag85B from M. avium subsp. paratuberculosis.  These results indicate that the M. avium subsp. paratuberculosis Ag85 homologues are immunodominant T-cell antigens that are recognized early in experimental and natural infection of cattle.
Descriptors:  cattle, Mycobacterium avium paratuberculosis, Mycobacterium bovis, protective antigens, synthetic Sauton medium, cultural filtrate, experimentally infections, B6 bg/bg beige mice, cattle, elevated spleen cell gamma interferon (IFN-[gamma]) secretion, lympho-proliferative responses of peripheral blood mononuclear cells, Ag85 homologues.

Rua-Domenech, R. de la; Goodchild, T.; Vordermeier, M.; Clifton-Hadley, R.  Ante mortem diagnosis of bovine tuberculosis: the significance of unconfirmed test reactors.  GVJ-Government Veterinary Journal.  2006; 16 (1): 65-71.  ISSN:  0269-5545
URL:   http://www.defra.gov.uk/gvs/publications/gvj/pdf/gvj-vol1701.pdf (PDF | 731KB)
Descriptors:  cattle, Mycobacterium bovis, diagnostic testing, intradermal tests, test reactors, zoonotic diseases.

Rua-Domenech, R.de la.  Bovine tuberculosis in the European Union and other countries: current status, control programmes and constrains to eradication.  GVJ-Government Veterinary Journal.  2006; 16 (1): 19-45.  ISSN:  0269-5545
URL:  http://www.defra.gov.uk/gvs/publications/gvj/pdf/gvj-vol1701.pdf (PDF | 731KB)
Descriptors:  cattle. Mycobacterium bovis, disease levels and distribution, zoonotic infections, control programs, issues limiting eradication, EC, USA, Africa, Canada, New Zealand, EU.

Rua-Domenech, R. de la; Goodchild, A.T.; Vordermeier, H.M.; Hewinson, R.G.; Christiansen, K. H.; Clifton-Hadley, R.S.  Ante mortem diagnosis of tuberculosis in cattle: a review of the tuberculin tests, gamma-interferon assay and other ancillary diagnostic techniques.  Research in Veterinary Science.  2006; 81 (2): 190-210.  ISSN:  0034-5288
URL:  http://www.sciencedirect.com/science/journal/00345288
NAL Call Number:  41.8 R312

Descriptors:  cattle, Mycobacterium bovis, diagnostic testing, live animals, cellular immunity tests, humoral antibody immunity tests, Mycobacterium bovis, PCR probes, electronic nose technology, sensitivity and specificity issues, eradication by culling skin reactors. 

Rudolph, B.A.; Riley, S.J.; Hickling, G.J.; Frawley, B.J.; Garner, M.S.; Winterstein, S.R.  Regulating hunter baiting for white-tailed deer in Michigan: biological and social considerations.  Wildlife Society Bulletin.  2006; 34 (2): 314-321.  ISSN:  0091-7648
URL:   http://joomla.wildlife.org/index.php?option=com_content&task=view&id=186&Itemid=248
NAL Call Number:  SK357.A1W5
Abstract:  Eradication of bovine tuberculosis (TB) from free-ranging white-tailed deer (Odocoileus virginianus) requires mortality rates of infected deer exceed the rate of new infection.  Efforts to reduce TB transmission in Michigan, USA, are based on 2 assumptions: (1) deer mortality may be increased through recreational hunting and (2) encounter rates between infected and noninfected deer may be reduced by prohibiting baiting and supplemental feeding.  Spatial correlation of TB-infected deer and supplemental feeding sites detected using aerial surveys validated a ban on artificial feeding in Michigan.  Similar analysis could not be used to evaluate the effects of a baiting ban because bait distribution was unknown.  Furthermore, a ban on deer baiting could confound attempts to increase deer mortality through reduced hunter participation or efficacy.  We reviewed the process used to evaluate a strategy for regulating bait use by hunters. This review included an assessment of 5 factors: statewide spatial analysis of apparent TB prevalence, deer intraspecific interactions at bait sites, effects of bait on hunter harvest rates, impacts of disease presence and practice of eradication efforts on hunting participation in the infected area and input from law enforcement personnel.  Our analysis suggested that restricting baiting to a limited, consistent region incurred less biological risk than allowing bait to be used statewide and less political risk than a statewide ban..
Descriptors:  cattle, white tailed deer (Odocoileus virginianus ), Mycobacterium bovis, feeding wild white tailed deer, transmission of disease, death rates, intraspecific interactions at bait sites, restricting baiting to a consistant region, feeding regulations, Michigan, USA.

Ryan, T.J.; Livingstone, P.G.; Ramsey, D.S.L.; de Lisle, G.W.; Nugent, G.; Collins, D.M.; Buddle, B.M.  Advances in understanding disease epidemiology and implications for control and eradication of tuberculosis in livestock: the experience from New Zealand.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4): 211-219.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, Held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:   A deteriorating tuberculosis problem in cattle and deer in New Zealand has been halted and then reversed over the last decade.  Mycobacterium bovis infection in both wild and domestic animal populations has been controlled.  This has been achieved by applying a multi-faceted science-based program.  Key features of this have been a comprehensive understanding of the epidemiology of tuberculosis in animals, confidence in sampling wild animal populations, effective application of diagnostic tests in cattle and deer, and the ability to map M. bovis genotypes.
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, disease control, disease control programs, deer, wildlife, animal diseases, tuberculosis, disease transmission, disease surveillance, diagnostic techniques, disease diagnosis, genotype, microbial genetics, strains, strain differences, pathogen eradication, serodiagnosis, New Zealand.

Sarma, K.K.; Bhawal, A.; Yadav, V.K.; Saikia, G.; Jogiraj Das.  Investigation of tuberculosis in captive Asian elephants of Assam vis-a-vis its cross infections with the handlersIntas Polivet.  2006; 7 (2): 269-274.  ISSN:  0972-1738
Descriptors:  Elephas maximus, disease screening, serum testing, indirect hemagglutination test (IHA), Mycobacterium, chemotherapy, clinical picture, disease surveillance, isonicotinic acid hydrazide, zoonotic infections, cross infection with human handlers, antibiotic treatment, isoniazid, streptomycin, Assam, India.

Scantlebury, M.; Harris, S.; Allcroft, D.J.; Hutchings, M.R.  Individual trade-offs between nutrition and risk of interspecific transmission of disease by grazing: cows, badger latrines and bovine tuberculosis.  Behaviour.  2006; 143 (2): 141-158. 
URL:  www.brill.nl
Descriptors:  bovine-tuberculosis, badgers (Meles meles), cattle, Mycobacterium bovis, cattle behaviors, dairy cows, use of pastures, correlations with physiological states, disease transmission from pastures, badger excreta, milk levels, differences in cattle behavior with just badger urine alone, disease risks, UK.

Scott-Park, F.; Biggs, A.  Premovement testing for bovine TB.  Veterinary Record (London) . 2006; 158 (16): 571.  ISSN:  0042-4900.  Note:  Correspondence.  
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  cattle, Mycobacterium bovis, predicting bovine TB movement, England, UK.

Semret, M.; Bakker, D.; Smart, N.; Olsen, I.; Haslov, K.; Behr, M.A.  Genetic analysis of Mycobacterium avium complex strains used for producing purified protein derivatives. Clinical and Vaccine Immunology.  2006; 13 (9): 991-996.  ISSN:  1556-6811
URL:  http://cvi.asm.org/
Abstract:  For over a century, purified protein derivatives (PPD) have been used to detect mycobacterial infections in humans and livestock.  Among these, reagents to detect infections by Mycobacterium avium complex organisms have been produced, but the utility of these reagents has not been clearly established due in part to limited biologic and immunologic standardization.  Because there is little information about the strains used to produce these reagents (avian PPD, intracellulare PPD, scrofulaceum PPD, and Johnin), we have performed genetic characterizations of strains used to produce these products.  Sequence analysis of 16S rRNA and the hsp65 gene provided results concordant with species designations provided for M. avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum organisms.  For M. avium strains, comparative genomic hybridization was performed on a whole-genome DNA microarray, revealing one novel 7.9-kilobase genomic deletion in certain Johnin-producing strains, in addition to genomic variability inherent to the particular M. avium subspecies.  Our findings indicate that considerable genomic differences exist between organisms used for reagents and the infecting organism being studied.  These results serve as a baseline for potency studies of different preparations and should aid in comparative studies of newly discovered antigens for the diagnosis of infection and disease by M. avium complex organisms.
Descriptors:  humans, livestock, diagnostic testing, genetic characterizations of strains used for PPD, Mycobacterium avium, Mycobacterium intracellulare.

Shitaye, J. E.; Getahun, B.; Alemayehu, T.; Skoric, M.; Treml, F.; Fictum, P.; Vrbas, V.; Pavlik, I.  A prevalence study of bovine tuberculosis by using abattoir meat inspection and tuberculin skin testing data, histopathological and IS6110 PCR examination of tissues with tuberculous lesions in cattle in Ethiopia.  Veterinarni Medicina.  2006; 51 (11): 512-522. 
URL:  http://www.vri.cz/docs/vetmed/51-11-512.pdf
NAL Call Number:  41.9 C333
Descriptors:  cattle, goats, sheep, Mycobacterium bovis, 10 year study, trends, tubercular lesions, abattoirs, prevalence levels, Addis Abba, Debre Zeit, Ethiopia.

Shitaye, J.E.; Parmova, I.; Matlova, L.; Dvorska, L.; Horvathova, A.; Vrbas, V.; Pavlik, I.  Mycobacterial and Rhodococcus equi infections in pigs in the Czech Republic between the years 1996 and 2004: the causal factors and distribution of infections in the tissues.  Veterinarni Medicina.  2006; 51(11): 497-511
URL:  http://www.vri.cz/docs/vetmed/51-11-497.pdf
Descriptors:  pigs, tuberculous/tuberculoid lesions, distribution of mycobacterial species and Rhodococcus equi in tissues, 3630 slaughtered pigs, microscopic examination and in vitro culture, various organ tissue sampled, gross lesions percentages, disease levels, Czech.

Silva, P.E.G. da; Pinheiro, S.R.; Leal, M.L.do R.; Bertagnon, H.G.; Motta, P.M.P.C.; Sinhorini, I.L.; Vasconcellos, S.A.; Benesi, F.J.  Teste de tuberculinizacao em caprinos (Capra hircus) experimentalmente sensibilizados.  [Tuberculin test in experimentally sensitized goats (Capra hircus)].  Ciencia Rural.  2006; 36 (3): 880-886.  ISSN:  0103-8478.  Note:  In Portuguese with an English summary.  
URL:  http://www.scielo.br/scielo.php/script_sci_serial/pid_0103-8478/lng_en/nrm_iso
NAL Call Number: S192.R4
Descriptors:  experimentally infected goats, tuberculin skin test, 3 test groups, sensitized with Mycobacterium avium sample D4, sensitized with Mycobacterium bovis sample AN5, saline inoculation control, sample cervical test, diagnostic techniques, skin fold thickness, mononuclear inflammatory infiltrates. 

Simion, N. The evolution of bovine tuberculosis incidence in Romania, in the period 2001-2005.  Slovenian Veterinary Research. 2006; 43(Supplement 10): 292.  Note:  Conference proceedings.  Edited by B. Zemljic.  7th Middle European Buiatric Congress, Radenci, Slovenia, 29 March-1 April 2006. Veterinarska Fakulteta, Univerza v Ljubljani, Slovenia.
Descriptors:  cattle, animal health surveillance, zoonotic diseases, tuberculosis, Mycobacterium bovis, bovine enzootic leucosis, bovine leukemia virus, disease incidence, disease prevalence, disease eradication, epidemiology, Romania.

Singh, A.S.; Pal, D.T.  Nutritional status of crossbred cows suffering from mastitis, metritis and tuberculosis.  Indian Veterinary Journal.  2006; 83 (7): 748-751.  ISSN:  0019-6479
URL:  www.indvetjournal.com
NAL Call Number:  41.8 IN2
Descriptors:  cattle, crossbred cows, Mycobacterium tuberculosis, mastitis, metritis, tuberculosis, nutritional status of diseased animals vs healthy animals, therapeutic nutrition of sick animals.

Singh, J.P.N.; Rishendra Verma; Chaudhuri, P.  Random amplified polymorphic DNA (RAPD) analysis of Mycobacterium bovis strain in India.  Indian Journal of Animal Sciences.  2006; 76 (11): 873-877.  ISSN:  0367-8318
NAL Call Number:  41.8 IN22
Descriptors:  buffalo, cattle, deer, Mycobacterium bovis AN5, M. bovis BCG, 20 field isolates, strain typing, RAPD-PCR, polymorphic amplicons, genetic defects, hereditary defects, heterogeneity, India.

Smith, G.C.  Persistence of disease in territorial animals: insights from spatial models of Tb.  New Zealand Journal of Ecology.  2006; 30 (1): 35-41.  ISSN:  0110-6465
NAL Call Number:  QH540.N43
Descriptors:  cattle, bovine tuberculosis, wildlife disease transmission, disease, modeling factors, chance, model artifacts, population (e.g. demographic, genetic) heterogeneity, environmental heterogeneity.

Soares-Magalhaes, R.; Smith, N.H.; Dale, J.; Gover, K.; Mitchell, A.; Mawdsley, J.; Stoker, N.G.  Investigating the cluster of Mycobacterium bovis spoligotype 13 strains in the southeast of England.  Society for Veterinary Epidemiology and Preventive Medicine Proceedings of a Meeting Held at Exeter, UK, 29-31 March 2006.  2006: 215-227.  ISBN:  0948073748
Descriptors:  cattle, badgers (Meles meles), high concentration of bovine tuberculosis, Mycobacterium bovis isolates, clonal relationships, spoligotype 13, cluster analysis, wildlife as disease reservoirs, East Sussex county England.

Swai, E.S.; Shirima, G.; Bwanga, S.; Moshy, W.  Bovine tuberculosis survey in urban and peri urban dairy farms in coastal humid region of Tanga, Tanzania.  Bulletin of Animal Health and Production in Africa.  2006; 54 (1): 75-78.  ISSN:  0378-9721
NAL Call Number:  41.8 B872
Descriptors:  dairy cattle, Mycobacterium bovis, disease surveillance, intradermal comparative tuberculin test, disease prevalence, Tanzania, Tanganyika.

Sweeney, F.P.; Courtenay, O.; Ul Hassan, A.; Hibberd, V.; Reilly, L.A.; Wellington, E.M.H.  Immunomagnetic recovery of Mycobacterium bovis from naturally infected environmental samples.  Letters in Applied Microbiology.  2006; 43 (4): 364-369.  ISSN:  0266-8254
URL: http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=lam
Descriptors:  cattle, environmental sampling for Mycobacterium bovis, Mycobacterium bovis BCG, seeded and naturally occurring soil, feces, urine, immunomagnetic capture technique, epidemiological importance of organism in the environment, bovine tuberculosis persistence.

Tadayon, K.; Mosavari, N.; Shahmoradi, A.H.; Sadeghi, F.; Azarvandi, A.; Forbes, K.  The epidemiology of Mycobacterium bovis in buffalo in Iran.  Journal of Veterinary Medicine B.  2006 Dec; 53 (1): 41-42.  ISSN:  0931-1793
URL:  http://www3.interscience.wiley.com/journal/118573245/abstract
NAL Call Number:  41.8 Z52
Abstract:  Mycobacterium bovis is the cause of bovine tuberculosis (bovine Tb) in animals and is considered to be zoonotic and accordingly it infects humans, although cattle are the main host.  Buffalo can also be infected and develop bovine Tb.  In Iran, almost half a million buffaloes are farmed, mainly in three provinces.  In West Azerbaijan, which has the largest numbers of buffaloes, cattle and buffalo are often farmed together.  According to the reports of the Iranian Veterinary Organization over the last 25 years, there have been no reports of bovine Tb in buffalo, although the disease is often reported in cattle in this province.  Eighteen and 140 pathology specimens from cattle and buffalo, respectively, collected from West Azerbaijani abattoirs were cultured.  From one buffalo specimen out of 140, M. bovis was recovered, whereas the pathogen was isolated from 13 cattle specimens.  Spoligotyping showed a relatively higher polymorphism within these isolates compared with M. bovis isolated from other Iranian provinces.
Descriptors:  Mycobacterium bovis, cattle, buffalo, epidemiology of the disease, post slaughter survey, West Azerbaijan, Iran.

Tanwar, R.K.  Pulmonary tuberculosis in camels (Camelus dromedarius).  Veterinary Practitioner.  2006; 7 (1): 17-18.  ISSN:  0972-4036
Descriptors:  dromedary camels, Mycobacterium, tuberculosis, clinical picture, lung effects, treatment, NSAIDS, sulfamethazine, sulphadimidine, terramycin, Rajasthan, India.

Taylor, C.; Jahans, K.; Palmer, S.; Okker, M.; Brown, J.; Steer, K.  Mycobacterium microti isolated from two pigs.  Veterinary Record (London). 2006; 159 (2): 59-60.  ISSN:  0042-4900
URL:  www.bvapublications.com
NAL Call Number:  41.8 V641
Descriptors:  8 month old, sand and black cross bred pigs, Mycobacterium microti UK type 19, Mycobacterium microtum, vole tuberculosis, case report, clinical picture, granuloma lesions, submandibular lymph nodes, multiple PCR, tuberculosis complex, spoligotyping, west Wales, UK.

Thoen, Charles O.; Steele, James H.; Gilsdorf, Michael J.  Mycobacterium bovis infection in animals and humans. 2nd ed. Ames, Iowa: Blackwell Pub. 2006.  329 p.: ill., maps.  ISBN: 0813809193 (alk. paper)
URL:  http://catdir.loc.gov/catdir/toc/ecip0515/2005018463.html
NAL Call Number:  RC311.19 .M93 2006
Descriptors:  tuberculosis in cattle. Mocobacterium bovis, AIDS disease complications.

Thoen, C.; LoBue, P.; Kantor, I. de.  The importance of Mycobacterium bovis as a zoonosis.  Veterinary Microbiology.  2006 Feb. 25; 112 (2-4): 339-345.  ISSN: 0378-1135.  Note:  Paper presented at the 4th International Conference on Mycobacterium bovis, held August 22-26, 2005, Dublin, Ireland.
URL:  www.sciencedirect.com/science/journal/03781135
NAL Call Number:  SF601.V44
Abstract:  Mycobacterium bovis and closely associated acid-fast bacilli cause disease in humans. Epidemiologic investigations reveal that the organism may be ingested or inhaled.  Extra pulmonary lesions may occur associated to the consumption of infected milk, even though with the practice of boiling milk, and the growth of milk pasteurization plants all over the world, the digestive route of infection became less important.  On the other hand, airborne infection continues to occur among meat industry and slaughterhouse workers, in regions where the infection is still prevalent in cattle.  Evidence of person to person transmission is rare.  Main causes of concern related to M. bovis in industrialized countries are: epizootics in domesticated and wild mammals and latent infection in immigrants.  Although multi-drug-resistant (MDR) strains of M. bovis have been identified, case reports reveal that anti-tuberculosis drugs routinely used to treat Mycobacterium tuberculosis-infected patients are effective when properly administered.
Descriptors:  cattle, food animals, Mycobacterium bovis, animal pathogenic bacteria, bovine tuberculosis, literature reviews, zoonoses, humans, tuberculosis, disease transmission, lesions animal, health hazards, occupational health and safety, livestock and meat industry, slaughterhouses, disease outbreaks, wild animals, latent period, multiple drug resistance, asymptomatic infections.

Thom, M.L.; Hope, J.C.; McAulay, M.; Villarreal-Ramos, B.; Coffey, T.J.; Stephens, S.; Vordermeier, H.M.; Howard, C.J.  The effect of tuberculin testing on the development of cell-mediated immune responses during Mycobacterium bovis infection.  Veterinary Immunology and Immunopathology.  2006 Nov 15; 114 (1-2): 25-36.  ISSN  0165-2427
URL:  http://dx.doi.org/10.1016/j.vetimm.2006.07.001
NAL Call Number:  SF757.2.V38
Abstract:  Protection against tuberculosis (TB) is associated with Th1-type cell-mediated immunity (CMI).  Whilst the intradermal injection of partially purified derivatives of tuberculin (PPD) represents the classic test assessing the delayed type hypersensitivity (DTH) response used in both humans and cattle for diagnosing TB, it has been suggested that the test may modulate host CMI responses.  To investigate the kinetics of the development of the DTH response and its subsequent effect on CMI responses, groups of 6-month old calves were inoculated intranasally with 8 x 10(4) cfu of Mycobacterium bovis, subjected to the comparative intradermal tuberculin test (TT) using bovine and avian PPD (PPD-B, PPD-A) at various time intervals post-infection, and immune responses compared.  These included DTH, lymphocyte proliferation, IgG production, and synthesis of the cytokines: IFN(Sd(B, IL-10, IL-4, IL-6, and IL-13.  All animals were subjected to post-mortem examination.  The kinetics of the development of the DTH response assessed in the TT was such that infected cattle could be identified as early as 3 weeks post-infection, which correlated with the detection of an antigen-specific IFN(Sd(B response.  Transient increases in plasma-derived IFN(Sd(B as a result of TT during an established TB infection were more pronounced when blood was stimulated with PPD-A compared with PPD-B stimulation.  This has the potential to mask diagnosis of infection as a result of the stronger avian-bias if the IFN(Sd(B test is used the week following TT.  Disease pathology was not affected by TT.  A transient failure to a second TT was observed in 1 of 30 animals and the time (post-infection) at which the TT is administered may be of significance.  In serum, IgG responses to PPD-B, which were undetectable prior to TT, were elevated after TT and were most pronounced in cattle that were TT at 6 weeks post-infection. Other cytokines were also affected by the TT; IL-4 mRNA levels increased and IL-6 mRNA levels decreased, whilst PPD-B specific IL-10 protein synthesis was enhanced.  These observations may offer the potential for further diagnostic assays that could complement the TT and IFN(Sd(B test.
Descriptors:  6 month old calves, intranasal inoculation, Mycobacterium bovis, cell mediated immunity, intradermal immunity testing, IFN (Sd(B. cytokines, IL-4mRNA levels increased, IL6 mRNA decreased, PPD-B specific IL-10 protein synthesis enhanced, diagnostic assays.

Twomey, D.F.; Crawshaw,.T.R.; Anscombe,.J.E.; Farrant,.L.; Evans,.L.J.; McElligott, W.S.; Higgins, R.J.; Dean, G.; Vordermeier, M.; Jahans, K.; Rua-Domenech, R. de la.  TB in llamas caused by Mycobacterium bovis.  Veterinary Record.  2007; 160 (5): 170.  ISSN:  0042-4900
URL:   http://veterinaryrecord.bvapublications.com/archive/
NAL Call Number:  41.8 V641
Descriptors:  llama herd, diagnosis of tuberculosis, Mycobacterium bovis, seroprevalence, antibody tests, intradermal tuberculin test, Devon, UK.

UK Department for Environment Food and Rural Affairs.  Special Issue: Bovine TB. GVJ-Government Veterinary Journal.  2006; 16 (1): 91 pp.  ISSN:  0269-5545.  Note:  Special issue contains 10 articles on TB.  
URL:  http://www.defra.gov.uk/gvs/publications/gvj/pdf/gvj-vol1701.pdf (PDF | 731KB)
Descriptors:  cattle, other species, Mycobacterium bovis, TB disease levels and distribution, TB policies, disease modeling, Bovigam assay, antemortem diagnosis, tuberculin skin test, zoonotic infections, control programs, issues limiting eradication, EC, USA, Africa, Canada, New Zealand, EU.

Vazquez-Flores, Felicitas; Alonso, Rogelio; Villegas-Sepulveda, Nicolas; Arriaga, Camila; Pereira-Suarez, Ana Laura; Mancilla, Raul; Estrada-Chavez, Ciro. A microsatellite study of bovine solute carrier family 11 a1 (Slc11a1) gene diversity in Mexico in relation to bovine tuberculosis. Genetics and Molecular Biology.  2006; 29 (3): 503-507.  ISSN: 
NAL Call Number:   QH426.R48
Descriptors:  cattle, Mycobacterium bovis, genetic susceptibility, polymorphisms, surveyed 34 European, 18 Asian, 20 Creole and 23 hybrid bovines, bovine solute carrier family 11 a1 (Slc11a1) gene, two microsatellite loci closely linked to this gene, levels of heterozygosity, 3' UTR microsatellite locus.

Vengust, G.; Zele, D.  Nekatere infekcijske bolezni pri jelenjadi v oborah s poudarkom na zoonozah.  [Some infectious diseases of deer in enclosures with emphasis on zoonosis.] Veterinarske Novice.  2006; 32 (3/4): 57-62.  ISSN:  0351-5842.  Note:  In Slovenian with an English summary.  
Descriptors:  fallow deer, red deer, deer farming, levels of disease, clinical signs, diagnosis, treatment and prevention, Bacillus anthracis, Brucella abortus, Cervus elaphus, Herpesviridae, Leptospira, Listeria monocytogenes, Malignant catarrhal fever virus, Mycobacterium avium ssp paratuberculosis, Mycobacterium bovis, Salmonella, Yersinia pseudotuberculosis, Slovenia.

Vitale, Fabrizio; Reale, Stefano; Petrotta, Enrico; Caracappa, Santo; Barera, Annalisa; La Manna, Marco Pio; Macaluso, Pasquale; Caccamo, Nadia; Dieli, Francesco; Vordermeier, Hans Martin; Sireci, Guido; Salerno, Alfredo.  ESAT-6 peptide recognition by bovine CD8(+) lymphocytes of naturally infected cows in herds from southern ItalyClinical and Vaccine Immunology.  2006; 13 (4): 530-533.  ISSN: 
URL:  http://cvi.asm.org/
NAL Call Number:  RB46.5
Descriptors:  define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8(+) T lymphocytes from cows naturally infected with Mycobacterium bovis, bovine CD8' T cells recognized 10 out of 11 ESAT-6 peptides tested.

Vordermeier, H.M.; Chambers, M.A.; Buddle, B.M.; Pollock, J.M.; Hewinson, R.G.  Progress in the development of vaccines and diagnostic reagents to control tuberculosis in cattle.  Veterinary Journal.  2006 Mar; 171 (2): 229-244.  ISSN:  1090-0233
URL:  http://dx.doi.org/10.1016/j.tvjl.2004.11.001
NAL Call Number:  SF601.V484
Abstract:  The sharp rise of bovine tuberculosis (TB) in Great Britain and the continuing problem of wild life reservoirs in countries such as New Zealand and Great Britain have resulted in increased research efforts into the disease.  Two of the goals of this research are to develop (1) cattle vaccines against TB and (2) associated diagnostic reagents that can differentiate between vaccinated and infected animals (differential diagnosis).  This review summarises recent progress and describes efforts to increase the protective efficacy of the only potential TB vaccine currently available, Mycobacterium bovis BCG, and to develop specific reagents for differential diagnosis.  Vaccination strategies based on DNA or protein subunit vaccination, vaccination with live viral vectors as well as heterologous prime-boost scenarios are discussed.  In addition, we outline results from studies aimed at developing diagnostic reagents to allow the distinction of vaccinated from infected animals, for example antigens that are not expressed by vaccines like Mycobacterium bovis Bacille-Calmette-Guerin, but recognised strongly in Mycobacterium bovis infected cattle.
Descriptors:  cattle, bovine tuberculosis,Mycoplasma bovis,drugs, vaccine development, literature reviews, Mycobacterium bovis BCG, BCG vaccine, live vaccines, subunit vaccines, disease detection, analytical methods, reagents, laboratory techniques, immunologic techniques, serodiagnosis, Mycobacterium tuberculosis complex.

Vordermeier, H. Martin; Huygen, Kris; Singh, Mahavir; Hewinson, R. Glyn; Xing, Zhou.  Immune responses induced in cattle by vaccination with a recombinant adenovirus expressing mycobacterial antigen 85A and Mycobacterium bovis BCG.  Infection and Immunity.  2006 Feb.; 74 (2) 1416-1418.  ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  Cattle were vaccinated with an adenovirus expressing the mycobacterial antigen 85A (rAd85A), with Mycobacterium bovis BCG followed by rAd85A heterologous boosting, or with rAd85A followed by BCG boosting, BCG/rAd85A resulted in the highest direct gamma interferon responses.  Cultured enzyme-linked immunospot assay analysis demonstrated that memory responses were induced by all three protocols but were strongest after BCG/rAd85A and rAd85A/BCG vaccination.
Descriptors:  cattle, Mycobacterium bovis BCG, vaccination, adenovirus expressing mycobacterial antigen 85A (rAd85A), 3 protocols, immune response.

Walravens, K.; Allix, C.; Supply, P.; Rigouts, L.; Godfroid, J.; Govaerts, M.; Portaels, F.; Dufey, J.; Vanholme, L.; Fauville-Dufaux, M.; Saegerman, C.  Dix annees d'epidemiologie moleculaire de la tuberculose bovine en Belgique.  [Ten years of molecular epidemiology of bovine tuberculosis in Belgium.]  Epidemiologie et Sante Animale.  2006; (49): 103-111.  ISSN:  0754-2186.  Note:  In French with an English summary.  
Descriptors:  cattle, Mycobacterium bovis, control and eradication programs, infections sporadic, 10 years of epidemiological data, Belgium.

Ward, A.I.; Tolhurst, B.A.; Delahay, R.J. Farm husbandry and the risks of disease transmission between wild and domestic mammals: a brief review focusing on bovine tuberculosis in badgers and cattle.  Animal Science (Penicuik). 2006; 82 (Part 6): 767-773.  ISSN:  1357-7298.  
URL:  http://journals.cambridge.org/action/displayJournal?jid=ASC
Descriptors:  wildlife as disease rervoirs, mammals, domesticated animals, disease transmission, European badgers (Meles meles), brushtail possums (Trichosurus vulpecula), culling strategies, changing livestock husbandry, farm management, Mycobacterium bovis, UK.

Waters, W.R.; Palmer, M.V.; Thacker, T.C.; Bannantine, J.P.; Vordermeier, H.M.; Hewinson, R.G.; Greenwald, R.; Esfandiari, J.; McNair, J.; Pollock, J.M.; Andersen, P; Lyashchenko, K.P.  Early antibody responses to experimental Mycobacterium bovis infection of cattle.  Clinical and Vaccine Immunology.  2006; 13 (6): 648-654.  ISSN:  1556-6811 (print).  ISSN:  1556-679X (on line)
URL:  http://cvi.asm.org/
NAL Call Number:  RB46.5
Descriptors:  Mycobacterium bovis, zoonotic diease, infected cattle sampling, seroractivity to mycobacterial antigens, experimentalinfection, various inoculation methods, aerosol, intratonsil, intranasal, multiantigen print immunoassay of antigen recognition patterns, immunoblot analysis for sensitive kinetic studies, VetTB STAT-PAK test based on lateral flow technology, MPB83, ESAT-6, CFP-10, and MPB70, rapidity of immune responses, potential of new antibody-based testing.

Waters, W.R.; Palmer, M.V.; Thacker, T.C.; Payeur, J.B.; Harris, N.B.; Minion, F.C. Greenwald, R.; Esfandiari, J.; Andersen, P.; McNair, J.; Pollock, J.M.; Lyashchenko, K.P.  Immune responses to defined antigens of Mycobacterium bovis in cattle experimentally infected with Mycobacterium kansasii.  Clinical and Vaccine Immunology.  2006; 13 (6): 611-619. ISSN:  1556-6811
URL:  http://cvi.asm.org/
NAL Call Number:  RB46.5
Descriptors:  calves, cross reactivity responses, Mycobacterium bovis, Mycobacterium kansasii, specificity of diagnostic tests, responses of calves shows responses that can confound testing for M. bovis.

Watrelot-Virieux, D.; Drevon-Gaillot, E.; Toussaint, Y.; Belli, P.  Comparison of three diagnostic detection methods for tuberculosis in French cattle.  Journal of Veterinary Medicine B.  2006; 53 (7): 321-325.  ISSN: 0931-1793
URL: http://www3.interscience.wiley.com/journal/118573200/abstract
NAL Call Number:  41.8 Z52
Abstract:  Three additional techniques (Ziehl-Neelsen, auramine O/rhodamine and immunostaining using polyclonal anti-Mycobacterium bovis) to hematoxylin-eosin histopathology were evaluated for bovine tuberculosis diagnosis on 39 samples from several slaughterhouses.  The immunohistochemical technique was more sensitive and could detect a greater number of positive cattle.  It has about the same sensibility as the bacteriology but it was faster.
Descriptors: French cattle, slaughtered animals, Mycobacterium bovis, pathogen detection methods, comparison study, France.

Werling, D.; Piercy, J.; Coffey, T.J.  Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells - potential role in pathogen discrimination?  Veterinary Immunology and Immunopathology.  2006; 112 (1/2): 2-11.  ISSN:  0165-2427
URL:  http://www.sciencedirect.com/science/journal/01652427
NAL Call Number:  SF757.2.V38
Descriptors:  cattle, Mycobacterium, antigenicity, immunogens, B and T lymphocytes, cellular defense mechanisms, immunity reactions, immunological reactions, mRNA, T cells, TOLL-like receptors (TLR), pathogen-associated molecular patterns, TLR2 in host defense against mycobacteria, mycobacteria species-specific response to bovine macrophages.

Winder, C.L.; Gordon, S.V.; Dale, J; Hewinson, R.G.; Goodacre, R.  Metabolic fingerprints of Mycobacterium bovis cluster with molecular type: implications for genotype-phenotype links.  Microbiology (Reading).  2006; 152 (9): 2757-2765.  ISSN:  1350-0872
URL:   http://mic.sgmjournals.org
Descriptors:  cattle, Mycobacterium bovis, bovine tuberculosis, tracing reservoirs of infection, Fourier-transform infrared spectroscopy (FT-IR), rapid phenotypic typing technique, multivariate cluster analysis, spoligotypes, genotype systematics, Britain, United Kingdom.

Widdison, S.; Schreuder, L.J.; Villarreal-Ramos, B.; Howard, C.J.; Watson, M.; Coffey, T.J.  Cytokine expression profiles of bovine lymph nodes: effects of Mycobacterium bovis infection and bacille Calmette-Guerin vaccination.  Clinical and Experimental Immunology.  2006; 144 (2): 281-289.  ISSN: 0009-9104
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number:  QR180.C5
Descriptors:  cattle, experimental infection, intranasal inoculation, comparison with non-inoculated animals, cytokine expression in lymph nodes, vaccination with Mycobacterium bovis BCG, lymph nodes with established tuberculosis and a persisting bacterial infection, maintenance of the pro-inflammatory response in combination with suppressed anti-inflammatory response may control the infection but contribute to host-induced tissue damage.

Woodroffe, R.; Donnelly, C.A.; Cox, D.R.; Bourne, F.J.; Cheeseman, C.L.; Delahay, R.J.; Gettinby, G.; McInerney, J.P.; Morrison, W.I.  Effects of culling on badger Meles meles spatial organization: implications for the control of bovine tuberculosis.  Journal of Applied Ecology.  2006; 43 (1): 1-10.  ISSN:  0021-8901
URL: http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=jpe
NAL Call Number:  410.J828ll
Abstract:  The incidence of bovine tuberculosis (TB) in British cattle has risen markedly over the last two decades.  Failure to control the disease in cattle has been linked to the persistence of a reservoir of infection in European badgers Meles meles, a nationally protected species.  Although badger culling has formed a component of British TB control policy for many years, a recent large-scale randomized field experiment found that TB incidence in cattle was no lower in areas subject to localized badger culling than in nearby areas where no experimental culls occurred.  Indeed, analyses indicated that cattle incidence was higher in culled areas.  One hypothesis advanced to explain this pattern is that localized culling disrupted badgers' territorial behaviour, potentially increasing the rate of contact between cattle and infected badgers.  This study evaluated this hypothesis by investigating badger activity and spatial organization in 13 study areas subjected to different levels of culling.  Badger home ranges were mapped by feeding colour-marked baits at badger dens and measuring the geographical area in which colour-marked faeces were retrieved. Badger home ranges were consistently larger in culling areas.  Moreover, in areas not subjected to culling, home range sizes increased with proximity to the culling area boundary.  Patterns of overlap between home ranges were also influenced by culling. Synthesis and applications.  This study demonstrates that culling badgers profoundly alters their spatial organization as well as their population density.  These changes have the potential to influence contact rates between cattle and badgers, both where culls occur and on adjoining land.  These results may help to explain why localized badger culling appears to have failed to control cattle TB, and should be taken into account in determining what role, if any, badger culling should play in future control strategies..
Descriptors:  cattle, badgers (Meles meles), bovine tuberculosis, culling of wild badger, wild animal disease reservoirs, home ranges, increased contact between badgers and cattle, UK.  

2005

AAEMA.  Journee AEEMA: 20 Mai 2005.  AEEMA Meeting, 20 May 2005.  Epidemiologie et Sante Animale.  2005; (48): 144 pp.  ISSN:  0754-2186.  Note:  In French.  A conference proceedings of 16 papers on infectious diseases in livestock. 
Descriptors:  pigs, goats, Piedmont cattle breed, sheep, birds, avian influenza virus, bluetongue virus, bovine diarrhea virus, Dermanyssus gallinae, Lawsonia bacteria, Mycobacterium, rabies virus, Salmonella, Toxoplasma, Lawsonia intracellularis, epidemiology, disease contols, clinical picture, Burgundy,Chad, Corsica, France, Italy, Piedmont, South East Asia, West Africa.  

Araujo, C.P. de; Leite, C.Q.F.; Prince, K.A. de; Jorge, K. dos S.G.; Osorio, A.L.A.R.  Mycobacterium bovis identification by a molecular method from post-mortem inspected cattle obtained in abattoirs of Mato Grosso do Sul, Brazil.  Memorias do Instituto Oswaldo Cruz.  2005; 100 (7): 749-752.  ISSN:  0074-0276
URL: http://www.scielo.br/scielo.php/script_sci_serial/pid_0074-0276/lng_en/nrm_iso
NAL Call Number:  448.9 IN74
Descriptors:  Mycobacterium bovis, bovine tuberculosis, post-slaughter testing, meat quality, contaminated meat products, carcasses with lesions, 23.6 % of samples positive for mycobacteria, Ziehl-Neelsen staining, PCR restriction enzyme patterns, 4 isolates identified, Mato Grosso do Sul, Brazil.

Arpan Maheshwari; Rishendra Verma  Evaluation of three antigens by enzyme-linked immunosorbent assay (ELISA) for the detection of Mycobacterium bovis infection in Indian cattle for field use.  Indian Journal of Animal Sciences.  2005; 75 (4): 401-406.  ISSN:  0367-8318
NAL Call Number:  41.8 IN22
Descriptors:  cattle herd testing, sera samples, Mycobacterium bovis, diagnosis, detection, purified protein derivative, protein rich soluble extract, species-specific phenolic glycolipid of Mycobacterium bovis AN5, antigens, ELISA, India.

Asseldonk, M.A.P.M. van; Roermund, H.J.W. van; Fischer, E.A.J.; Jong, M.C.M. de; Huirne, R.B.M.  Stochastic efficiency analysis of bovine tuberculosis-surveillance programs in the Netherlands.  Preventive Veterinary Medicine.  2005; 69 (1/2): 39-52.  ISSN:  0167-5877
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/503315/description#description

NAL Call Number:  SF601.P7
Descriptors:  bovine tuberculosis, stochastic bio-economic model, cost efficient surveillance program, epidemiological module, dynamics of detection, probability of detection, visual examination of carcass lesions at slaughter, GAMMA-interferon testing of blood samples, two state tuberculin testing, future may use ELISA testing of bulk tank milk in combination with slaughter examination, Netherlands.

Baird, G.  Caseous lymphadenitis in goats.  Goat Veterinary Society Journal.  2005; 21: 21-23.  ISSN:  0961-2548
Descriptors:  goats, caseous lesions, bacterial pathogens found, Actinobacillus lignieresii, Arcanobacterium pyogenes, Corynebacterium pseudotuberculosis, Mycobacterium, Staphylococcus aureus, Yersinia pseudotuberculosis, UK.

Barrett, D.C.  Cattle Review 2005 Parts 41-43.  Cattle Practice.  2005; 13 (3): 277-280.  ISSN:  0969-1251
NAL Call Number:  SF961.C37
Descriptors:  cattle, dairy cows, housing, fertility, semen storage, sperm survival, artificial insemination, estrous cycle, hormones, progesterone, reproduction, embryonic development, dry period in dairy cows, nutrition and energy balance, lactation, mammary glands, lameness, estrous cycle, progesterone, reproduction, bovine tuberculosis, Mycobacterium bovis, reviews.

Bernard, F.; Vincent, C.; Matthieu, L.; David, R.; James, D.  Tuberculosis and brucellosis prevalence survey on dairy cattle in Mbarara milk basin (Uganda).  Preventive Veterinary Medicine.  2005; 67 (4): 267-281.  ISSN:  0167-5877
URL:  http://www.sciencedirect.com/science/journal/01675877
Descriptors:  dairy cattle, Brucella, Mycobacterium bovis, 340 herds tested, intradermal skin test, prevalence survey, age differences, sex differences, breed differences, seroprevalence of pathogens, Mbarara, Uganda.

Bernardelli, A.; Nicola, A.; Alonso, B.; Alonso, Z.; Ulens, K.; Morcillo, N.; Cordero, G.; Cataldi, A.; Zumarraga, M.; Paolicchi, F.; Torres, P.; Kistermann, J.C.; Madero, J.E.  Tuberculosis Bovina: evaluacion de tecnicas de diagnostico.  [Bovine tuberculosis: evaluation of diagnostic techniques.]  Revista de Medicina Veterinaria Buenos Aires.  2005; 86 (5): 183, 194.  ISSN:  0325-6391.  Note:  In Spanish with an English summary.  
Descriptors:  cattle; Mycobacterium bovis; diagnostic techniques; sensitivity; specificity; agreement; kappa Bovigamtv CSL kit was 88%, 73%, 82% and 0.62; LCx Mycobacterium tuberculosis ASSAY-ABBOTT was 28%, 91%, 46% and 0.13; Mycobacterial Growth Indicator Tube system was 0, 100%, 37% and 0; Ziehl-Neelsen stained method it was 1%, 92%, 47% and -0.6; culture in Lowestein-Jensen was 0, 99%, 51% and -0.12; culture in Stonebrink was 2%, 93%, 51% and -0.5; PCR IS6110 probe in milk samples of 55%, specificity was 96%, agreement was 73% and kappa was 0.49.

Bourne, J.; Donnelly, C.A.; Cox, D.R.; Gettinby, G.; McInerney, J.P.; Morrison, I.; Woodroffe, R. Bovine tuberculosis: towards a future control strategy. Cattle Practice.  2005; 13 (4): 289-294.  ISSN:  0969-1251.  Note:  Reprinted from Veterinary Record.  2003; 167: 207-210.
NAL Call Number:  SF961.C37
Descriptors:  badgers (Meles meles), cattle, Mycobacterium bovis, pathogenesis, diagnosis, disease prevalence, disease control programs, disease prevention, wildlife as disease reservoirs, disease transmission, UK.

Bourne, J.; Donnelly, C.A.; Cox, D.R.; Gettinby, G.; McInerney, J.P.; Morrison, W.I.; Woodroffe, R.  Bovine tuberculosis - towards a science based control strategy.  Cattle Practice.  2005; 13 (4): 319-322.  ISSN:  0969-1251.  Note:  Reprinted from Science in Parliament. 2005; 62: 25-28.
NAL Call Number:  SF961.C37
Descriptors:  cattle, badgers (Meles meles), wild animal disease reservoir, transmission risks, Mycobacterium bovis, animal welfare, control programs; culling, diagnosis, disease control, disease prevalence and prevention, disease surveys, epidemiological surveys, epidemiology, molecular epidemiology, vaccination, vaccines.

Buddle, B.M.; Wedlock, D.N.; Denis, M.; Skinner, M.A.  Identification of immune response correlates for protection against bovine tuberculosis. Veterinary Immunology and Immunopathology.  2005 Oct. 18; 108 (1-2): 45-51.  ISSN: 0165-2427.  Note:  Paper presented at the 7th International Veterinary Immunology Symposium Held July 25-30, 2004, Quebec, Canada.
URL: http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number:  SF757.2.V38
Descriptors:  calves, bovine tuberculosis, disease prevention, immune response, vaccines, Mycobacterium bovis, vaccination, cell mediated immunity, interferons, subcutaneous injection, messenger RNA, gene expression, interleukin 4, tuberculin, disease detection, disease severity, literature reviews.

Buddle, B.M.; Aldwell, F.E.; Skinner, M.A.; Lisle, G.W. de; Denis, M.; Vordermeier, H.M.; Hewinson, R.G.; Wedlock, D.N.  Effect of oral vaccination of cattle with lipid-formulated BCG on immune responses and protection against bovine tuberculosis.  Vaccine.  2005; 23 (27): 3581-3589.
URL:  http://www.sciencedirect.com/science/journal/0264410X
Descriptors:  calves, Mycobacterium bovis, Mycobacterium bovis BCG strain vaccine, oral route, 108 colony forming units or 10 pellets of 109 CFU, subcutaneous injections with 106 CFU, varied immune responses, challenge with virulent Mycobacterium bovis, caudal fold tuberculin skin test post vaccination, interferon, interleukin 2, T lymphocytes, lungs, procedure produced significant level of protection compared to non-vaccination.

Cadmus, S.I.B.; Arinola, O.G.  Evaluation of the 48 hour, 72 hour and 96 hour readings of tuberculin test for the screening of tuberculosis in cattle.  African Journal of Clinica and Experimental Microbiology.  2005; 6 (3): 223-226.  ISSN:  1595-689X
URL:
http://www.ajol.info/viewarticle.php?jid=47&id=23100&layout=abstract&OJSSID=37fb63efacde72211b5d1fd3c840f425

Descriptors:  cattle, Mycobacterium tuberculosis, tuberculin testing, screening, comparison of reading times.

Cadmus, S.I.B.; Atsanda, N.N.; Oni, S.O.; Akang, E.E.U.  Bovine tuberculosis in one cattle herd in Ibadan in Nigeria.  Veterinarni Medicina.  2004; 49 (11): 406-412.  ISSN:  0375-8427
Descriptors:  1 private herd, N'dama and White Fulani (i.e. Bunaji) breeds, bovine tuberculosis survey, introdermal comparative cervical tuberculin test, clinical aspects, diagnosis, diagnostic techniques, disease prevalence, epidemiology, histopathology, molecular epidemiology, Nigeria.

Cai, H.; Tian, X.; Hu, X.D.; Li, S.X.; Yu, D.H.; Zhu, Y.X.  Combined DNA vaccines formulated either in DDA or in saline protect cattle from Mycobacterium bovis infection.  Vaccine.  2005; 23 (30): 3887-3895.  ISSN:  0264-410X
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/30521/description#description

Descriptors:  DNA vaccines, Mycobacterium tuberculosis antigens Ag85B, MPT64, MPT83, testing on calves, vaccine plus dimethyldioctyldecyl ammonium bromide (DDA) or saline elicited a strong gamma interferon (IFN-gamma) response, 1 or 2 months post 3rd vaccination, titers, BCG challenge.

Carrique-Mas, J.J.; Medley, G.F.; Green, L.E.  Risk of bovine tuberculosis breakdowns in post-foot-and-mouth disease restocked cattle herds in Great Britain.  In:  Mellor, D.J.; Russell, A.M.; Wood, J.L.N. (Editors).  Society for Veterinary Epidemiology and Preventive Medicine Proceedings of a Meeting Held at Nairn, Inverness, Scotland, 30th March 1st April-2005.  Published by the Society.  2005: 27-41.  ISBN:  0948073691
Descriptors:  cattle, bovine tuberculosis, Mycobacterium bovis, disease control, foot and mouth disease virus, FMD, hazards, risk assessment of animal movements, repopulation purchasing risk factors; survival, Great Britain.

Cedeno, I.; de Obaldia, R.; Sanjur, O.; Bayard, V.; Ortega-Barria, E.; Escobar, C.  Use of the polymerase chain reaction for diagnosing bovine tuberculosis in PanamaRevue Scientifique et Technique Office International des Epizooties.  2005; 24(3): 1067-1075.  ISSN:  0253-1933
NAL Call Number:  SF781.R4
Descriptors:  cattle industry, Mycobacterium bovis, 60 nasal mucus samples, diagnostic testing, PCR species specific primers for diagnostic program, zoonotic threat to public health, Panama.

Cobos-Marin, L.; Montes-Vargas, J.; Zumarraga, M.; Cataldi, A.; Romano, M.I.; Estrada-Garcia, I.; Gonzalez-y-Merchand, J.A.  Spoligotype analysis of Mycobacterium bovis isolates from Northern Mexico.  Canadian Journal of Microbiology.  2005 Nov.; 51 (11): 996-1000.  Note:  In English with a French summaryEnglish.  ISSN: 0008-4166
URL:  http://pubs.nrc-cnrc.gc.ca/rp-ps/journalDetail.jsp?jcode=cjm&lang=eng
NAL Call Number:  448.8 C162
Descriptors:  cattle, Mycobacterium bovis, animal pathogenic bacteria, strains, bovine tuberculosis, genetic techniques and protocols, polymerase chain reaction, loci, repetitive sequences, spoligotyping, spacer oligonucleotide typing, spoligotypes, Mexico.

Collins, J.D.  The control of tuberculosis in cattle: an Irish view.  Cattle Practice.  2005; 13 (4): 361-367.  ISSN:  0969-1251
NAL Call Number:  SF961.C37
Descriptors:  cattle, badgers (Meles meles), Mycobacterium bovis, Irish Republic.

Cousins, D.V.; Florisson, N.  A review of tests available for use in the diagnosis of tuberculosis in non-bovine species.  Revue Scientifique et Technique Office International des Epizooties.  2005 December; 24 (3): 1039-1059.  ISSN:  0253-1933.  Note:  In English with summaries in English, French and Spanish.
Descriptors:  bovine tuberculosis, negative social and economic impacts, affects domestic and wild animals, animal diversity, zoonotic diseases, intradermal tuberculin test, ELISA, prescribed test for diagnosis in cattle, Mycobacterium bovis, review of various tests used for diagnosis, validated diagnostics for different species, number of animals used for test validation.

Cox, D.R.; Donnelly, C.A.; Bourne, F.J.; Gettinby, G.; McInerney, J.P.; Morrison, W.I.; Woodroffe, R.  Simple model for tuberculosis in cattle and badgers.  Proceedings of the National Academy of Sciences of the United States of America.  2005 Dec 6; 102 (49): 17588-17593.  ISSN:  0027-8424
URL:  http://www.pnas.org/
NAL Call Number:  500 N21P
Abstract:  As an aid to the study of bovine tuberculosis (TB), a simple model has been developed of an epidemic involving two species, cattle and badgers.  Each species may infect the other.  The proportion of animals affected is assumed relatively small so that the usual nonlinear aspects of epidemic theory are avoided.  The model is used to study the long-run and transient effect on cattle of culling badgers and the effect of a period without routine testing for TB, such as occurred during the 2001 epidemic of foot-and-mouth disease in Great Britain.  Finally, by examining the changes in cattle TB over the last 15 years, and with some other working assumptions, it is estimated that the net reproduction number of the epidemic is approximately equal to 1.1.  The implications for controlling the disease are discussed.
Descriptors:  cattle, bovine tuberculosis, Mycobacterium bovis, disease transmission, epidemiology, badgers (Meles meles), modeling disease transmission, effects of culling badgers, testing interruption, disease control, UK.

Dean, Gillian S.; Rhodes, Shelley G.; Coad, Michael; Whelan, Adam O.; Cockle, Paul J.; Clifford, Derek J.; Hewinson, R. Glyn; Vordermeier, H. Martin.  Minimum infective dose of Mycobacterium bovis in cattle.  Infection and Immunity.  2005 Oct; 73 (10): 6467-6471.  ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  The aim of this work was to determine the minimum infective dose of Mycobacterium bovis necessary to stimulate specific immune responses and generate pathology in cattle.  Four groups of calves (20 animals) were infected by the intratracheal route with 1,000, 100, 10, or 1 CFU of M. bovis.  Specific immune responses (gamma interferon {IFN-[gamma]} and interleukin-4 [IL-4] responses) to mycobacterial antigens were monitored throughout the study, and the responses to the tuberculin skin test were assessed at two times.  Rigorous post mortem examinations were performed to determine the presence of pathology, and samples were taken for microbiological and histopathological confirmation of M. bovis infection.  One-half of the animals infected with 1 CFU of M. bovis developed pulmonary pathology typical of bovine tuberculosis.  No differences in the severity of pathology were observed for the different M. bovis doses.  All animals that developed pathology were skin test positive and produced specific IFN-[gamma] and IL-4 responses.  No differences in the sizes of the skin test reactions, the times taken to achieve a positive IFN-[gamma] result, or the levels of the IFN-[gamma] and IL-4 responses were observed for the different M. bovis doses, suggesting that diagnostic assays (tuberculin skin test and IFN-[gamma] test) can detect cattle soon after M. bovis infection regardless of the dose. This information should be useful in modeling the dynamics of bovine tuberculosis in cattle and in assessing the risk of transmission.
Descriptors:  cattle, Mycobacterium bovis, experimental infection, varying dosages, skin test reactions, diagnostic assays, progress of infection, mathmetical modeling of disease, risk of transmission. 

Delahay, R.J.; Cheeseman, C.L; Mallinson, P.J; Rogers, L.M.; Smith, G.C.  Badgers and bovine tuberculosis: a review of studies in the ecology of a wildlife disease reservoir.  Cattle Practice.  2005; 13(4): 295-299.  ISSN:  0969-1251
NAL Call Number:  SF961.C37
Descriptors:  wild badgers (Meles meles), cattle, wild animals as disease reservoirs, Mycobacterium bovis, UK.

Denis, Michel; Keen, Denise L.; Wedlock, D. Neil; de Lisle, Geoffrey W.; Buddle, Bryce M.  Susceptibility of brushtail possums (Trichosurus vulpecula) infected with Mycobacterium bovis is associated with a transient macrophage activation profile.  Tuberculosis (Amsterdam).  2005; 85 (4): 235-244.  ISSN:  1472-9792
URL:
http://www.elsevier.com/wps/find/journaldescription.cws_home/638428/description?navopenmenu=-2

Descriptors:  Australian brushtail possum (Trichosurus vulpecula), wildlife reservoir for pathogen, Mycobacterium bovis virulent strain, pathogenesis, disease process, experimental infection, aerosol exposure, lung lesions, livers, spleens, blood lymphocytes proliferated, nitric oxide levels in lungs, tumor necrosis factor alpha, transient activation of alveolar macrophages, New Zealand.

Dhakal, M.; Shrestha, R.G.; Jha, V.C.; Dhakal, P.R.; Sato, T.; Morita, Y.; Kozawa, K.; Kimura, H.  Heat treatment effects on Mycobacterium spp. isolated from ruminants in Nepal.  Veterinary Microbiology.  2005; 106 (3-4): 303-304.  ISSN:  0378-1135
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description

NAL Call Number:  SF601.V44
Descriptors:  Jersey cow, Murrah buffalo, Mycobacterium avium, Mycobacterium bovis, strains NPMb-2 and NPMb-1, Mycobacterium thermoresistible strains NPMth-2 and NPMth-1, Mycobacterium fortuitum strain NPMfo-1, heat treatment effects, applied and field techniques, single intradermal cervical tuberculin test: SICT, clinical techniques, diagnostic techniques, Nepal.

Dunn, John R.; Kaneene, John B.; Grooms, Daniel L.; Bolin, Steven R.; Bolin, Carole A.; Bruning Fann, Colleen S.  Effects of positive results for Mycobacterium avium subsp paratuberculosis as determined by microbial culture of feces or antibody ELISA on results of caudal fold tuberculin test and interferon-gamma assay for tuberculosis in cattle.  Journal of the American Veterinary Medical Association.  2005; 226(3): 429-435.  ISSN: 0003-1488
URL:  http://avmajournals.avma.org/loi/javma
NAL Call Number:  41.8 AM3
Descriptors:  cattle, comparison study, positive potential of false positives for Mycobacterium bovis if positive for M. avium ssp paratuberculosis, microbial culture of feces or antibody ELISA, caudal fold tuberculin test or interferon-gamma assay for M. bovis, no significant association was established, 10 herds in Michigan.

Efford, M.; Norbury, G.  Ferret population assessment: progress and challenges.  In:  13th Australasian Vertebrate Pest Conference, Wellington, New Zealand, 2-6 May 2005.  Published by Manaaki Whenua Press, Landcare Research.  Lincoln, New Zealand.  2005: 75-80.  
Descriptors:  cattle, ferrets, Mycobacterium bovis, wild animal disease reservoirs, disease vectors, bait traps; baiting, baits, capture of feral animals, control programs, dispersal of feral animals, invasions, population levels, methodology, pest control, pest management, population density, population dynamics, reservoir hosts, trapping, vertebrate pests, wild animals, New Zealand.

Fend, R.; Geddes, R.; Lesellier, S.; Vordermeier, H.M.; Corner, L.A.L.; Gormley, E.; Costello, E.; Hewinson, R.G.; Marlin, D.J.; Woodman, A.C.; Chambers, M.A.  Use of an electronic nose to diagnose Mycobacterium bovis infection in badgers and cattle.  Journal of Clinical Microbiology.  2005; 43 (4): 1745-1751.  ISSN:  0095-1137
URL:  http://jcm.asm.org/cgi/content/abstract/43/4/1745
NAL Call Number:  QR46.J6
Abstract:  It is estimated that more than 50 million cattle are infected with Mycobacterium bovis worldwide, resulting in severe economic losses.  Current diagnosis of tuberculosis (TB) in cattle relies on tuberculin skin testing, and when combined with the slaughter of test-positive animals, it has significantly reduced the incidence of bovine TB.  The failure to eradicate bovine TB in Great Britain has been attributed in part to a reservoir of the infection in badgers (Meles meles). Accurate and reliable diagnosis of infection is the cornerstone of TB control.  Bacteriological diagnosis has these characteristics, but only with samples collected postmortem.  Unlike significant wild animal reservoirs of M. bovis that are considered pests in other countries, such as the brushtail possum (Trichosurus vulpecula) in New Zealand, the badger and its sett are protected under United Kingdom legislation (The Protection of Badgers Act 1992).  Therefore, an accurate in vitro test for badgers is needed urgently to determine the extent of the reservoir of infection cheaply and without destroying badgers.  For cattle, a rapid on-farm test to complement the existing tests (the skin test and gamma interferon assay) would be highly desirable.  To this end, we have investigated the potential of an electronic nose (EN) to diagnose infection of cattle or badgers with M. bovis, using a serum sample.  Samples were obtained from both experimentally infected badgers and cattle, as well as naturally infected badgers.  Without exception, the EN was able to discriminate infected animals from controls as early as 3 weeks after infection with M. bovis, the earliest time point examined postchallenge.  The EN approach described here is a straightforward alternative to conventional methods of TB diagnosis, and it offers considerable potential as a sensitive, rapid, and cost-effective means of diagnosing M. bovis infection in cattle and badgers..
Descriptors:  Mycobacterium bovis detection, electronic nose, badgers (Meles meles), cattle, sero testing.

Fischer, E.A.J.; van Roermund, H.J.W.; Hemerik, L.; van Asseldonk, M.A.P.M.; De Jong, M.C.M.  Evaluation of surveillance strategies for bovine tuberculosis (Mycobacterium bovis) using an individual based epidemiological modelPreventive Veterinary Medicine.  2005; 67 (4): 283-301.  ISSN:  0167-5877
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503315/description#description
NAL Call Number:  SF601.P7
Descriptors:  bovine tuberculosis status, surveillance system, visual inspection of carcasses at slaughter, ELISA blood sampling post slaughter, gamma-interferon, pre-slaughter of herds and ELISA test on bulk milk, stochastic individual based model simulating a chain of infected herds, epidemiological modeling, possible effects of one infected animal into one herd, analysis of optimization of a 6 approaches, Netherlands.

Fishwick, J. (editor).  Cattle practice.  Cattle Practice.  2005; 13 (4): 183 pp.  ISSN:  0969-1251.  Note:  Special issue on bovine tuberculosis.  
NAL Call Number:  SF961.C37
Descriptors:  cattle, bovine tuberculosis, Mycobacterium bovis, Mycobacterium bovis BCG strain, Trichosurus vulpecula, Meles meles, diagnosis, diagnostic techniques, disease control programs, disease prevalence, disease transmission, disease vectors and reservoirs, vaccination, wild animals.

Fikru, R.; Bonnet, P.; Moges, W.  Prevalence of bovine tuberculosis in indigenous Zebu cattle under extensive farming system in Western Ethiopia.  Bulletin of Animal Health and Production in Africa.  2005; 53(1): 85-88.  ISSN:  0378-9721.  Note:  In English with a French summary.  
URL:  http://www.ajol.info/journal_index.php?ab=bahpa
NAL Call Number: 41.8 B872
Descriptors:  indigenous zebu cattle, bovine tuberculosis, Mycobacterium bovis, disease survey, 35 small holder extensive production, housing, feeding, cattle movement patterns, cattle diseases, purpose of cattle keeping, respiratory diseases, trypanosomiasis, black leg, anthrax, diarrhea, etc, intradermal tuberculin tests, modes of disease transmission, Bodji district, Ethiopia.

Foote, M.R.; Nonnecke, B.J.; Waters, W.R.; Palmer, M.V.; Beitz, D.C.; Fowler, M.A.; Miller, B.L.; Johnson, T.E.; Perry, H.B.  Effects of increased dietary protein and energy on composition and functional capacities of blood mononuclear cells from vaccinated, neonatal calves.  International Journal for Vitamin and Nutrition Research.  2005 Sept.; 75 (5): 357-368.  ISSN: 0300-9831
URL:  http://www.verlag-hanshuber.com/zeitschriften/journal.php?abbrev=VIT
NAL Call Number:  389.8 Z33
Abstract:  Effects of increased protein and energy provided by an intensified milk replacer on the antigen-specific, cell-mediated immune response of the neonatal calf were examined.  Calves were fed a standard (0.45 kg/day of a 20% crude protein, 20% fat milk replacer; n = 11) or intensified (1.14 kg/day of a 28% crude protein, 20% fat milk replacer; n = 11) diet from 0 to 6 weeks of age.  All calves were vaccinated with Mycobacterium bovis bacillus Calmette-Guerin (BCG) at 1 week of age.  The daily weight gain of intensified-diet calves (0.62 kg/day) was greater than the weight gain of standard-diet calves (0.29 kg/day).  Liver, kidney, heart, thymus, and subcervical lymph nodes from intensified-diet calves were heavier than the same organs from standard-diet calves.  Flow cytometric analysis of peripheral blood mononuclear cell (PBMC) populations indicated that CD4+ cells, gamma delta TCR+ cells, and monocyte percentages, although unaffected by diet during the first 5 weeks of the study, were higher in intensified-diet calves at week 6.  The decline in gamma delta d TCR+ cell percentages and increase in B cell percentages with increasing age seen in all calves are characteristic of the maturing immune system of the calf.  CD8+ T cell or B cell percentages were not affected by diet.  In intensified-diet calves, percentages of CD4+ expressing interleukin-2 receptor increased and percentages of gamma delta TCR+ cells expressing interleukin-2 receptor decreased with time.  The same populations in standard-diet calves did not change with time.  Percentages of CD4+ and CD8+ T cells, and B cells expressing MHC class II antigen, were unaffected by diet or age.  Although mitogen-induced interferon (IFN)-gamma and nitric oxide (NO) secretion increased with age for all calves, PBMC from intensified-diet calves produced less IFN-gamma and more NO than did cells from standard-diet calves at week 6 of the study.  Antigen-induced secretion of IFN-gamma and NO also increased with age but was unaffected by diet.  Antigen-elicited delayed-type hypersensitivity was unaffected by diet, suggesting increased dietary protein and energy did not alter adaptive immunity in vivo.  Overall, these results suggest that feeding calves a commercially available, intensified milk replacer affects minimally the composition and functional capacities of PBMC populations.  Additional research is necessary to determine whether these subtle effects influence the calf's susceptibility to infectious disease.
Descriptors:  calves, neonates, calf feeding, dietary protein, dietary energy sources, monocytes, vaccination, milk replacer, immune response, cell mediated immunity, crude protein, CD8+ T lymphocytes, Mycobacterium bovis BCG, BCG vaccine, bovine tuberculosis, liveweight gain, animal organs, tissue weight, CD4+T lymphocytes, B lymphocytes, interleukin 2, major histocompatibility complex, histocompatibility antigens, interferons.

Gallagher, J.  Tuberculosis: tracing the dilemma.  Veterinary Times.  2005; 35 (27): 14-17.  ISSN:  1352-9374
Descriptors:  badgers (Meles meles) as pathogenic disease reservoirs, cattle, Mycobacterium bovis, epidemiology, disease prevalence and transmission, seasonal effects, disease control strategies, trapping, pathobiology, absesses, various organs with lesions, latent infections, vaccines, bites, wounds, mortality rates, England.

Gilbert, M.; Mitchell, A.; Bourn, D.; Mawdsley, J.; Clifton-Hadley, R.; Wint, W.  Cattle movements and bovine tuberculosis in Great Britain.  Nature. 2005; 435 (7041): 491-496.  ISSN: 0028-0836
URL:  http://www.nature.com/index.html
NAL Call Number:  472 N21
Abstract:  For 20 years, bovine tuberculosis (BTB) has been spreading in Great Britain (England, Wales and Scotland) and is now endemic in the southwest and parts of central England and in southwest Wales, and occurs sporadically elsewhere.  Although its transmission pathways remain poorly understood, the disease's distribution was previously modelled statistically by using environmental variables and measures of their seasonality.  Movements of infected animals have long been considered a critical factor in the spread of livestock diseases, as reflected in strict import/export regulations, the extensive movement restrictions imposed during the 2001 foot-and-mouth disease outbreak, the tracing procedures after a new case of BTB has been confirmed and the Government's recently published strategic framework for the sustainable control on BTB.  Since January 2001 it has been mandatory for stock-keepers in Great Britain to notify the British Cattle Movement Service of all cattle births, movements and deaths.  Here we show that movements as recorded in the Cattle Tracing System data archive, and particularly those from areas where BTB is reported, consistently outperform environmental, topographic and other anthropogenic variables as the main predictor of disease occurrence.  Simulation distribution models for 2002 and 2003, incorporating all predictor categories, are presented and used to project distributions for 2004 and 2005.
Descriptors:  cattle, bovine tuberculosis, Mycobacterium bovis, animal transport, geographical distribution, disease transmission tracking, epidemiology, simulation models, Great Britain.

Green, L.E.; Cornell, S.J.  Investigations of cattle herd breakdowns with bovine tuberculosis in four counties of England and Wales using VETNET data.  Preventive Veterinary Medicine.  2005 Sept 12; 70 (3-4): 293-311.  ISSN:  0167-5877
NAL Call Number:  SF601.P7
Abstract:  Cattle herd breakdown (HBR) with bovine tuberculosis (BTB) was investigated for farms in four counties of England and Wales outside southwest England from 1986 to early 2000.  Data from the national database of TB testing history (VETNET) were used.  Factors that influenced HBR included calendar time, herd size, number of cattle tested, the test type, the inter-test interval and spatial grouping of farms.  Herd tests other than routine herd tests had an increased risk of HBR in all four counties.  In all counties, the risk of HBR increased with calendar time and in Shropshire a test interval of 3 years was associated with an increased risk of HBR compared with a 1-year test interval.  In Staffordshire and Sussex, a 4-year test interval was associated with a lower risk of HBR compared with a 1-year test interval.  There was no evidence of spatial clustering of HBR in West Glamorgan (equal spatial risk in a 15-30 km radius) and weak evidence of spatial clustering in Shropshire (7-15 km) and Sussex (5-10 km).  In Staffordshire, there was evidence of spatial (2-4 km) and time (3-4 years) clustering of HBR.  The locally increased rate of testing following a confirmed HBR increased the detection of infected herds but did not prevent local spread in two of the four counties (Shropshire and Staffordshire) since the rate of HBR increased linearly from 1988 to 2000.  The main conclusion is that there were both local and distant components of spread.
Descriptors:  dairy cattle, Mycobacterium bovis, bovine tuberculosis, disease prevalence, disease transmission, herd size, risk assessment, risk factors, herd health, databases, herd breakdown, VETNET database, England, Wales.

Green, L.  Modelling disease - a guide for the cattle practitionerCattle Practice.  2005; 13 (3): 243-248.  ISSN:  0969-1251
NAL Call Number:  SF961.C37
Descriptors:  cattle, cattle diseases, Mycobacterium bovis, foot and mouth disease, disease models, mathematical models, statistical models, analysis, risk assessment, infectious disease processes, disease transmission hypotheses.

Griffin, J.M.; Williams, D.H.; Kelly, G.E.; Clegg, T.A.; O' Boyle, I.; Collins, J.D.; More, S.J.  The impact of badger removal on the control of tuberculosis in cattle herds in Ireland.  Preventive Veterinary Medicine, 2004; 67: 237-266.  ISSN:  0167-5877
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503315/description#description
NAL Call Number:  SF601.P7
Descriptors:  badgers (Meles meles), cattle, Mycobacterium bovis, diagnosis, disease prevention and control programs, disease-prevalence, wild life as disease reservoirs, epidemiology, regression analysis, trapping, vector control, wild animals, Irish Republic.

Griffin, J.M.; More, S.J.; Clegg, T.A.; Collins, J.D.; O'Boyle, I.; Williams, D.H.; Kelly, G.E.; Costello, E.; Sleeman, D.P.; O' Shea, F.; Duggan, M.; Murphy, J.; Lavin, D.P.T.  Tuberculosis in cattle: the results of the four-area project.  Irish Veterinary Journal.  2005; 58 (11): 629-636.  ISSN:  0368-0762.
URL:  www.veterinary-ireland.org
NAL Call Number:  41.8 IR4
Descriptors:  Mycobacterium bovis, outbreaks, cattle, badgers (Meles meles), epidemiology, disease control and prevention, disease prevalence, disease transmission, wild badgers as a disease pathogen reservoir, reviews, Irish Republic.

Griffin, J.M.; Clegg, T.A.; Kelly, G.E.; Williams, D.H.; O'Boyle, I.; Collins, J.D.; More, S.J.  The impact of badger removal on the control of tuberculosis in cattle herds in Ireland.  In:  D.J. Mellor; A.M. Russell; J.L.N. Wood (Editors).  Society for Veterinary Epidemiology and Preventive Medicine Proceedings of a Meeting Held at Nairn, Inverness, Scotland, 30th March 1st April 2005.  Published by Society for Veterinary Epidemiology and Preventive Medicine.  Roslin, UK.  2005; 42-54.  ISBN:  0948073691
Descriptors:  cattle, badgers (Meles meles), Mycobacterium bovis, disease control, disease vectors, risk assessment, survival, tuberculosis, Ireland.

Hewes, C.A.; Schneider, R.K.; Baszler, T.V.; Oaks, J.L.  Septic arthritis and granulomatous synovitis caused by infection with Mycobacterium avium complex in a horse. Journal of the American Veterinary Medical Association.  2005 June 15; 226 (12): 2035-2038.  ISSN:  0003-1488
NAL Call Number:  41.8 Am3
Descriptors:  horses, arthritis, sepsis (infection), horse diseases, synovitis, Mycobacterium avium complex, mycobacterial diseases, lameness, case studies, pain, granulomatous-synovitis

Hope, J.C.; Thom, M.L.; Villareal-Ramos, B; Vordermeier, H.M.; Hewinson, R G; Howard, C J.  Exposure to Mycobacterium avium induces low-level protection from Mycobacterium bovis infection but compromises diagnosis of disease in cattle (vol 141, pg 432, 2005).  Clinical and Experimental Immunology.  2005; 142 (3): 595.  ISSN:  0009-9104.   Note:  Errata: article.
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number:  QR180.C5
Descriptors:  Mycobacterium bovis, effects of exposure to Mycobacterium avium, skin testing, cattle testing and diagnosis unreliable.

Hope, J.C.; Thom, M.L.; Villarreal-Ramos, B.; Vordermeier, H.M.; Hewinson, R.G.; Howard, C.J.  Exposure to Mycobacterium avium induces low-level protection from Mycobacterium bovis infection but compromises diagnosis of disease in cattle.  Clinical and Experimental Immunology.  2005; 141 (3): 432-439.  ISSN:  0009-9104
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number:  QR180.C5
Descriptors:  calves, Mycobacterium avium exposure, Mycobacterium bovis challenge, immune responses, exposure to Mycobacterium avium may mask diagnosis of Mycobacterium bovis infection even with specific antigens can contribute to disease transmission in the field.  

Hope, J.C.; Thom, M.L.; Villarreal-Ramos, B.; Vordermeier, H.M.; Hewinson, R.G.; Howard, C.J.  Exposure to Mycobacterium avium induces low-level protection from Mycobacterium bovis infection but compromises diagnosis of disease in cattle.  Clinical and Experimental Immunology.  2005; 141 (3): 432-439.  ISSN:  0009-9104
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number:  QR180.C5
Descriptors:  calves, cattle diseases, Mycobacterium avium, Mycobacterium bovis, bacterial antigens, diagnosis, diagnostic techniques, experimental infections, development of immune response, immunity, interferon, T lymphocytes, pathogenesis, postmortem examinations, skin tests, tuberculin.

Hope, J.C.; Thom, M.L.; Villarreal-Ramos, B.; Vordermeier, H.M.; Hewinson, R.G.; Howard, C.J.  Vaccination of neonatal calves with Mycobacterium bovis BCG induced protection against intranasal challenge with virulent M. bovis (vol 139, pg 48, 2005).  Clinical and Experimental Immunology.  2005; 140 (1): 192.  ISSN:  0009-9104.  Note:  Errata; Article.
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number:  QR180.C5
Descriptors:  neonatal calves, vaccination with Mycobacterium bovis, BCG, level of protection with trans-nasal challenge with virulent Mycobacterium bovis.

Hope, J.C.; Thom, M.L.; Villarreal-Ramos, B.; Vordermeier, H.M.; Hewinson, R.G.; Howard, C.J.  Vaccination of neonatal calves with Mycobacterium bovis BCG induces protection against intranasal challenge with virulent M. bovisClinical and Experimental Immunology.  2005; 139 (1): 48-56.  ISSN:  0009-9104
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0009-9104
NAL Call Number:  QR180.C5
Descriptors:  2 week old calves, neonates vaccinated with Mycobacterium bovis BCG, Mycobacterium bovis, virulent strain challenge intra-nasally, experimental infection, tissue examined for lesions, chest lymph nodes, neonate vaccination induced significant protection against disease, potential for disease control.

Jahans, K.L.; Worth, D.; Brown, J.; Monies, R.J.  Detection of bovine tuberculosis in spill-over hostsResearch in Veterinary Science.  2005; 78 (Suppl. A): 23-24.  ISSN:  0034-5288.  Note:  Meeting abstract.  59th Annual Conference of the Association for Veterinary Teaching and Research Work, Scarborough, England; March 21 -23, 2005 
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/623070/description#description
NAL Call Number:  41.8 R312
Descriptors:  Mycobacterium bovis, cattle, buffalo, bison, sheep, goats, dogs, deer, cats, badgers, pigs, domestic and wildlife species, spill over hosts, end hosts, animal pathogen reservoirs, maintenance hosts.

Jesenska, Andrea; Pavlova, Martina; Strouhal, Michal; Chaloupkova, Radka; Tesinska, Iva; Monincova, Marta; Prokop,-Zbynek; Bartos, Milan; Pavlik,  Ivo; Rychlik, Ivan; Moebius, Petra; Nagata, Yuji; Damborsky, Jiri.  Cloning, biochemical properties, and distribution of mycobacterial haloalkane dehalogenases.  Applied and Environmental Microbiology.  2005; 71 (11): 6736-6745.  ISSN:  0099-2240
URL: http://www.pubmedcentral.nih.gov/tocrender.fcgi?action=archive&journal=83
NAL Call Number:  448.3 Ap5
Descriptors:  Mycobacterium bovis, Mycobacterium tuberculosis, haloalkane dehalogenases, enzymes, cloning of enzyme genes dmbA and dmbB of M. bovis 5033/66, dehalogenase activity of translation products, distribution of genes in following species--Mycobacterium bovis, Mycobacterium bovis BCG, Mycobacterium africanum, Mycobacterium caprae, Mycobacterium microti, and Mycobacterium pinnipedii, characterization of proteins, evolution and distribution of haloalkane dehalogenases among mycobacteria.

Jiang, XiuYun; He, ZhaoYang.  DNA injection via in vivo electroporation: a new immunisation technique for bovine tuberculosis.  Chinese Journal of Zoonoses.  2005; 21 (2): 182-184.  ISSN:  1002-2694.  Note:  In Chinese.  
Descriptors:  cattle, pigs, sheep, Mycobacterium bovis, DNA injection technique, immune reactions, vaccines, electroporation, immunization, 2 different vaccines used with no interference between them.

Kumar, K.; Swamy, M.  Miliary tuberculosis in cross-bred cows.  Indian Journal of Veterinary Pathology.  2005; 29 (1): 50-51.  ISSN:  0250-4758
Descriptors:  cattle, tuberculosis, Mycobacterium tuberculosis, India.  

Lutze Wallace, C.; Turcotte, C.; Sabourin, M.; Berlie-Surujballi, G.; Barbeau, Y.; Watchorn, D.; Bell, J.  Spoligotyping of Mycobacterium bovis isolates found in Manitoba.  Canadian Journal of Veterinary Research = Revue Canadienne de Recherche Veterinaire.  2005 Apr; 69 (2): 143-145.  ISSN: 0830-9000.  Note:  In English with a French summary.
URL:  http://www.pubmedcentral.nih.gov/tocrender.fcgi?action=archive&journal=133
NAL Call Number:  SF601.C24
Descriptors:  deer, cattle, elk, Cervus elaphus Canadensis, Mycobacterium bovis, microsatellite repeats, 44 isolates, tissue sources, hybridized with oligonucleotide 12 (MB-1 type), oligonucleotide 12 (MB-1 type), oligonucleotide 12 (MB-2 type), Manitoba, Canada.

Lutze-Wallace, C.; Turcotte, C.  Laboratory diagnosis of bovine tuberculosis in Canada for calendar year 2004.  Canadian Veterinary Journal.  2005; 46 7(9): 797-799.  ISSN:  0008-5286.  Note:  In English and French.
URL:  http://www.pubmedcentral.nih.gov/tocrender.fcgi?action=archive&journal=202
NAL Call Number:  41.8 R3224
Descriptors:  wild animals, zoo animals, livestock, bison, cattle, Cervus elaphus, deer, elephants, equines, cats, bacterial disease, Mycobacterium, Mycobacterium avium, Mycobacterium avium ssp paratuberculosis, Mycobacterium bovis, Mycobacterium fortuitum, Mycobacterium kansasii, Mycobacterium flavescens, Mycobacterium triviale, Mycobacterium terrae, red deer, pigs, Suiformes, disease diagnosis, disease surveys, Alberta, British Columbia, Manitoba, Ontario, Quebec, Saskatchewan, Canada.

Mahendra-Pal  Importance of zoonoses in public health.  Indian Journal of Animal Sciences.  2005; 75 (5): 586-591.  ISSN:  0367-8318
NAL Call Number: 41.8 IN22
Descriptors:  cattle, humans, wild animals, Mycobacterium bovis, Yersinia pestis, zoonotic diseases, animal diseases, disease prevalence, control programs, disease prevention, epidemiology, human diseases, morbidity, mortality, plague, public health, sanitation, hygiene, zoonoses, Gujarat, Maharashtra, India, USA.

Maheshwari, Arpan; Verma, Rishendra.  Evaluation of three antigens by enzyme-linked immunosorbent assay (ELISA) for the detection of Mycobacterium bovis infection in Indian cattle for field use.  Indian Journal of Animal Sciences.  2005; 75 (4): 401-406.  ISSN:  0367-8318
NAL Call Number: 41.8 IN22
Descriptors:  Mycobacterium bovis AN5, crude antigens form purified protein derivative PPD, species specific phenolic glycolipid, 3 groups of cattle, cattle testing with tuberculin, not tuberculin tested, tuberculin testing in last 14 days, sera collected, ELISA assay, histogram cut off values ELISA assay with PPD, sensitivity and specificity of assay depends on population tested.

Manal, S.H.; Hamid, M.E.; El Jalii, I.M.; Ali, A.S.  Correlation between microscopic examination and culture for detection and differentiation of mycobacterial isolates from cattle in the Sudan.  Pakistan Journal of Biological Sciences.  2005; 8 (2): 284-286.
Descriptors:  cattle, postmortem sampling, slaughtered animals, lymph nodes, tuberculous lungs, histopathology, microscopic examination Zeilh-Neelsen stain, culture on Lowenstein-Jensen (L-J) medium, detection and differentiation of mycobacterium species isolates, Mycobacterium farcinogenes, Mycobacterium bovis, differential detection, Khartoum State, Sudan.

Maue, Alexander C.; Waters, W. Ray; Davis, William C.; Palmer, Mitchell V.; Minion, F. Chris; Estes, D. Mar.  Analysis of immune responses directed toward a recombinant early secretory antigenic target six-kilodalton protein-culture filtrate protein 10 fusion protein in Mycobacterium bovis infected cattle.  Infection and Immunity.  2005 Oct; 73 (10): 6659-6667.  ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  Cell-mediated immune responses are critical for protective immunity to mycobacterial infections.  Recent progress in defining mycobacterial antigens has determined that region of difference 1 (RD1) gene products induce strong T-cell responses, particularly the early secretory antigenic target 6-kDa (ESAT-6) protein and culture filtrate protein 10 (CFP10).  However, comprehensive analysis of the immune response towards these antigens is incompletely characterized.  To evaluate recall responses to ESAT-6 and CFP10, peripheral blood mononuclear cells from M. bovis-infected cattle were stimulated in vitro with a recombinant ESAT-6 (rESAT-6)-CFP10 fusion protein and compared to responses induced by M. bovis-derived purified protein derivative.  Following antigenic stimulation, activation marker expression was evaluated.  Significant proliferative responses (P < 0.05) were evident in CD4+, CD8+, immunoglobulin M-positive, and CD172a+ cell fractions after 6 days of culture.  Expression of CD25 and CD26 was increased (P < 0.05) on CD4+, CD8+, and [gamma][delta] T-cell-receptor-positive cells.  CD4+ and CD8+ cells also exhibited significant changes (P < 0.05) in expression of CD45 isoforms.  Using a flow cytometry-based proliferation assay, it was determined that CD45R expression is downregulated (P < 0.05) and that CD45RO expression is upregulated (P < 0.05) on proliferating (i.e., activated) CD4+ cells.  Collectively, data indicate that recall immune responses directed toward the rESAT-6-CFP10 fusion protein or purified protein derivative are comparable and that recall to mycobacterial antigens correlates with a CD45RO+ phenotype.
Descriptors:  cattle, cell-mediated responses, mycobacterian antigens, 1 (RD1) gene products, T cell responses, 6kDa (ESAT 6) protein and culture filtrate protein 10 (CFP10), animal experiment.

McCorry, T.; Whelan, A.O.; Welsh, M.D.; McNair, J.; Walton, E.; Bryson, D.G.; Hewinson, R.G.; Vordermeier, H.M.; Pollock, J.M.  Shedding of Mycobacterium bovis in the nasal mucus of cattle infected experimentally with tuberculosis by the intranasal and intratracheal routes.  Veterinary Record.  2005 Nov. 12; 157 (20) 613-618.  ISSN: 0042-4900
URL: http://veterinaryrecord.bvapublications.com/
NAL Call Number:  41.8 V641
Descriptors:  cattle, Mycobacterium bovis, disease transmission, experimental infection, routes of infection, pathogen shedding, nasal mucus.

Mdegela, R.H.; Karimuribo, E.; Kusiluka, L.J.M.; Kabula, B.; Manjurano, A.; Kapaga, A.M.; Kambarage, D.M.  Mastitis in smallholder dairy and pastoral cattle herds in the urban and peri-urban areas of the Dodoma municipality in Central Tanzania.  Livestock Research for Rural Development.  2005; 17 (11): 123.  ISSN:  0121-3784
Descriptors:  64 small holder dairy cattle, disease levels, ELISA, single comparative intradermal tuberculin tests, Arcanobacterium pyogenes, Aspergillus, Bacillus, Brucella, Escherichia coli, Klebsiella, Mucor, Mycobacterium sp, Mycobacterium avium complex, Mycobacterium fortuitum, Mycobacterium phlei, Mycobacterium smegmatis, Serratia, Staphylococcus, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus intermedius, Hyphomycetes, Mucoraceae, Mycobacterium flavescens, Mycobacterium gordonae, Dodoma, Tanzania.

Mellor, D.J.; Russell, A.M.; Wood, J.L.N. (Editors).  Society for Veterinary Epidemiology and Preventive Medicine. Proceedings of a Meeting Held at Nairn, Inverness, Scotland, 30th March-1st April 2005.  Published by the Society.  2005.  277 pp.  ISBN:  0948073691.
Descriptors:  many papers, topics include animals diseases, epidemiology, disease prevalence, disease transmission and spread, disease control and prevention, diagnosis, reservoir hosts, public health aspects, bovine tuberculosis, Mycobacterium bovis, classical swine fever, rabies, pancreatic necrosis virus, foot and mouth disease, avian influenza A virus, Streptococcus suis, Escherichia coli, Campylobacter, Salmonella spp., Ostertagia ostertagi, broilers, domestic livestock, wild animal disease carriers, UK.

Menzies, F.D.; Neill, S.D.  Bovine tuberculosis: controlling cattle-to-cattle transmissionCattle Practice.  2005; 13 (4): 441-446.  ISSN:  0969-1251
NAL Call Number:  SF961.C37
Descriptors:  cattle, Mycobacterium bovis, transmission between cattle, controlling disease spread.

Monaghan, M.L.; Doherty, M L.; Collins, J.D.; Kazda, J.F.; Quinn, P.J.  The tuberculin test.  Cattle Practice.  2005; 13 (4): 337-345.  ISSN:  0969-1251
NAL Call Number:  SF961.C37
Descriptors:  cattle, Mycobacterium bovis, tuberculin skin testing, efficacy, UK.

Morales, A.; Martinez, I.; Carlos, A.; Alvarez, G.; Alvarez, M.; Maldonado, J.  Comparacion de histopatologia, cultivo y PCR en el diagnostico de tuberculosis bovina.  [Comparison of histopathology, culture and PCR in the diagnosis of bovine tuberculosis.]  Revista Cientifica, Facultad de Ciencias Veterinarias, Universidad del Zulia.  2005; 15 (2): 103-108.  ISSN:  0798-2259.  Note:  In Spanish with an English summary.  
Descriptors:  cattle, Mycobacterium bovis, bovine tuberculosis, tuberculin testing, diagnosis, diagnostic techniques, histopathology, PCR of tissue, histopathological analysis, bacterial isolation, Mexico.

More, S.J. Towards eradication of bovine tuberculosis in Ireland: a critical review of progress.  Cattle Practice.  2005; 13 (4): 313-318.  ISSN:  0969-1251
NAL Call Number:  SF961.C37
Descriptors:  cattle diseases, Mycobacterium bovis, tuberculosis control program, disease transmission from wildlife to cattle, wildlife disease reservoir, cattle to cattle transmission, epidemiology, development of a vaccine for badgers (Meles meles), eradication strategy, Irish Republic.

More, S.J.  Towards eradication of bovine tuberculosis in Ireland: a critical review of progress.  In:  D.J. Mellor; A.M. Russell; J.L.N. Wood. (Editors).  Society for Veterinary Epidemiology and Preventive Medicine Proceedings of a Meeting Held at Nairn, Inverness, Scotland, 30th March-1st April, 2005.  Published by the Society.  2005; 13-23.  ISBN:  0948073691
Descriptors:  Mycobacterium bovis, bovine tuberculosis, eradication program, evidence of disease transmission badgers to cattle, wildlife reservoirs difficult to control, program for effective vaccine for badgers, Ireland.

Morrison, W.I.; Bourne, F.J.; Cox, D.R.; Donnelly, C.A.; Gettinby, G.; McInerney, J.P.; Woodroffe, R.  Pathogenesis and diagnosis of infections with Mycobacterium bovis in cattle.  Cattle Practice.  2005; 13 (4): 351-360.  ISSN:  0969-1251
NAL Call Number:  SF961.C37
Descriptors:  cattle, Mycobacterium bovis, disease development, pathogenesis, diagnostic approaches, UK.

Neill, S.D.; Skuce, R.A.; Pollock, J.M.  Tuberculosis - new light from an old window.  Journal of Applied Microbiology.  2005; 98 (6): 1261-1269.  ISSN:  1364-5072
URL:  http://www3.interscience.wiley.com/journal/118490255/home
NAL Call Number:  QR1.J687
Descriptors:  bovine tuberculosis, zoonotic aspects, new information about Mycobacterium bovis, recent developments, pathogenesis, epidemiology, disease eradication, diagnosis, vaccination.

Nonnecke, B.J.; Waters, W.R.; Foote, M.R.; Palmer, M.V.; Miller, B.L.; Johnson, T.E.; Perry, H.B.; Fowler, M.A.  Development of an adult-like cell-mediated immune response in calves after early vaccination with Mycobacterium bovis bacillus Calmette-Guerin.  Journal of Dairy Science.  2005 Jan.;88(1): 195-210.  ISSN: 0022-0302
URL:  http://jds.fass.org/contents-by-date.0.shtml
NAL Call Number:  44.8 J822
Descriptors:  Mycobacterium bovis BCG, lymphocyte proliferation, T lymphocytes.

Nonnecke, B.J.; Waters, W.R.; Foote, M.R.; Palmer, M.V.; Miller, B.L.; Johnson, T.E.; Perry, H.B.; Fowler, M.A.  Development of an adult-like cell-mediated immune response in calves after early vaccination with Mycobacterium bovis bacillus Calmette-Guerin.  Journal of Dairy Science.  2005; 88 (1): 195-210.  ISSN:  0022-0302
URL:  http://jds.fass.org/contents-by-date.0.shtml
NAL Call Number:  44.8 J822
Descriptors:  Holstein bull calves, effects of neonatal vaccination, young adults, attenuated strain of Mycobacterium bovis BCG, effects on antigen-specific cellular and humoral immune responses, ontogeny of adaptive immune response, functional capacities of blood mononuclear cell populations, 1-12 week time periods, nulliparous heifers vaccinated, effects of animal maturity on response, bovine neonate can mount a vigorous, adult like cell mediated immune response after early age vaccination.

Norby, B.; Bartlett, P.C.; Grooms, D.L.; Kaneene, J.B.; Bruning-Fann, C.S.  Use of simulation modeling to estimate herd-level sensitivity, specificity, and predictive values of diagnostic tests for detection of tuberculosis in cattle.  American Journal of Veterinary Research.  2005; 66 (7): 1285-1291
Descriptors:  cattle herds, Mycobacterium bovis, diagnosis, diagnostic techniques, estimation, computer simulation models for testing scenarios for tuberculosis, Michigan, US.

O'Rourke, K.  Teasing out Mycobacterium bovis' role in the tuberculosis crisis.  Journal of the American Veterinary Medical Association.  2005; 227 (6): 871.  ISSN:  0003-1488
URL:  http://avmajournals.avma.org/loi/javma
NAL Call Number:  41.8 AM3
Descriptors:  cattle, humans, meat, meat products, milk, food contamination, Mycobacterium bovis, epidemiology, disease distribution, disease prevalence, disease transmission, zoonoses.

Oakey, J.; Forbes-Faulkner, J.; Gilpin, C.; Murdoch, B.; Johnson, S.  Pyogranuloma caused by Mycobacterium asiaticum infection in a steer.  Journal of Veterinary Diagnostic Investigation.  2005 July; 17 (4): 378-382.  ISSN:  1040-6387
NAL Call Number:  SF774.J68
Abstract:  In 2003, a steer carcass was condemned at a Central Queensland abattoir because of metastatic tumors. In addition, a granulomatous lesion was found in the mediastinal lymph node. Histological examination showed this to be a pyogranuloma, typically associated with Rhodococcus or the Nocardia/Streptomyces group.  However, in this case, the only etiological agent was an acid-fast bacillus, which would normally be associated with a more fibrous lesion.  A number of nucleic acid-based techniques were used, and the isolate was identified as Mycobacterium asiaticum.  This organism is a rarely encountered opportunistic pathogen of humans, associated with subtropical climates.  This is the first report of this organism causing infection in cattle.  The similarities between this case and cases of human disease are discussed.
Descriptors:  cattle, steer, Mycobacterium asiaticum, granulomatous lesions, mycobacterial diseases, case study, neoplasms, inflammation, pathogenesis, disease diagnosis, pyogranuloma, Australia.

Olea-Popelka, F.J.; Flynn, O.; Costello, E.; McGrath, G.; Collins, J.D.; O'Keeffe, J.; Kelton, D.F.; Berke, O.; Martin, S.W. Spatial relationship between strains in cattle and badgers in four areas in Ireland.  Preventive Veterinary Medicine.  2005; 71 (1-2): 57-70.  ISSN:  0167-5877
URL:http://www.elsevier.com/wps/find/journaldescription.cws_home/503315/description#description
NAL Call Number:  SF601.P7
Descriptors:  Mycobacterium bovis strains, cattle, Meles meles, badgers setts, centroid of a cattle farm, logistic model, spatial clusters of strains, can be both in cattle and badgers, wild animals as reservoirs, dynamics of badger movements, epidemiology, transmission of bacteria from badgers to cattle, 4 areas of Ireland.

Olea-Popelka, F.J.; Phelan, J.; White, P.W.; McGrath, G.; Collins, J.D.; O' Keeffe, J.; Duggan, M.; Collins, D.M.; Kelton, D.F.; Berke, O; More, S.J.; Martin, S.W.  Quantifying badger exposure and the risk of bovine tuberculosis for cattle herds in county Kilkenny, Ireland.  Preventive Veterinary Medicine.  2006; 75 (1/2): 34-46.  
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503315/description#description
NAL Call Number:  SF601.P7

Descriptors:  badgers (Meles meles), quantifying badger exposure, cattle, bovine tuberculosis risk, Ireland.

Oru C, E. Meningoencephalitis tuberculosa in a Holstein Cow.  Veterinary Pathology.  2005 Nov; 42 (6): 856-858.  ISSN:  0300-9858
NAL Call Number:  41.8 P27
Abstract:  The gross and histopathologic lesions of meningoencephalitis tuberculosa in a 4-year-old Holstein cow showing clinical signs compatible with bovine spongiform encephalopathy are described in this report.  Grossly, numerous gray to yellow, firm and caseous nodules were seen on the ventral surfaces of the brain and in the lateral and fourth ventricles.  Histopathologically, foci of caseation and dystrophic mineralization were surrounded by multinucleated giant cells, epitheloid macrophages, plasma cells, lymphocytes and fibrous proliferation.  Ziehl-Neelsen stains of the lesions revealed masses of slender acid-fast bacilli in the necrotic centers of lesions and within surrounding giant cells. 
Descriptors:  dairy cows, brain infection, histopathology, bovine tuberculosis, Mycobacterium, disease diagnosis, case study.

Palmer, Mitchell V.; Waters, W. Ray; Thacker, Tyler C.; Stoffregen, William C.; Thomsen, Bruce V.; Slaughter, Ralph E.; Jones, Stephen L.; Pitzer, Josh E.; Minion, F. Chris.  Experimental infection of reindeer (Rangifer tarandus) with Mycobacterium bovis: pathological & immunological findings.  Proceedings.  Annual Meeting of the United States Animal Health Association.  2005; 108: 113-116.  ISSN:  0082-8750
URL:  http://www.usaha.org/Meetings.aspx/
NAL Call Number:  49.9 UN3R
Descriptors:  reindeer (Rangifer tarandus), Mycobacterium bovis, bovine tuberculosis, experimental infection, disease pathology, disease process, immunological responses, diagnostic techniques.

Parra, A.; Larrasa, J.; Garcia, A.; Alonso, J.M.; Hermoso de Mendoza, J.  Molecular epidemiology of bovine tuberculosis in wild animals in Spain: A first approach to risk factor analysis.  Veterinary Microbiology.  2005 Oct. 31; 110 (3-4): 293-300.  ISSN: 0378-1135
URL:http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number:  SF601.V44
Descriptors:  Mycobacterium bovis, animal pathogenic bacteria, risk factors, epidemiology, bovine tuberculosis, wild animals, ungulates, genetic markers, hosts, loci, symptoms, seasonal variation, disease prevalence, molecular epidemiology, reproductive season, hunting season, Spain.

Pavlik, I.; Trcka, I.; Parmova, I.; Svobodova, J.; Melicharek, I.; Nagy, G.; Cvetnic, Z.; Ocepek, M.; Pate, M.; Lipiec, M.  Detection of bovine and human tuberculosis in cattle and other animals in six Central European countries during the years 2000-2004.  Veterinarni Medicina.  2005; 50 (7): 291-299.  ISSN:  0375-8427
Descriptors:  cattle, zoo animals, Bactrian camels (Camelus ferus) in Czech Repuglic, a Siberian tiger (Panthera tigris f. altaica) in Hungary, a bison (Bison bison), an eland (Taurotragus oryx) in Poland, a dromedary camel (Camelus dromedarius), two bison in Slovenia, in wild animals, wild boar, wild red deer, European bison, roe deer, skin testing, disease status, Mycobacterium bovis, 6 Central European countries, Croatia, the Czech Republic, Hungary, Poland, Slovakia, and Slovenia.

Pavlik, I.; Jahn, P.; Chvatal, O.; Kalova, L.; Matlova, L.; Dvorska, L.; Treml, F.; Nesnalova, E.; Novotny, L.; Halouzka, R.  Plicni tuberkuloza u kone zpusobena puvodcem aviarni tuberkulozy.  [Pulmonary tuberculosis in a horse caused by the causal agent of avian tuberculosis.]  Veterinarstvi.  2005; 55 (3): 140-145.  ISSN:  0506-8231.  Note:  In Czech with an English summary.  ISSN:  0506-8231
Descriptors:  horses, 16 year old mare, interstitial pneumonia, lung infection, case study, Mycobacterium avium, Mycobacterium avium ssp. avium serotype 2 and genotypes dnaJ+, IS901+ and IS1245+isolates, Commission Decision No. 2004/320/EC of 31 March 2004, free of bovine tuberculosis, sporadic findings, Czech Rebuplic.

Pfeiffer, D.U.  TB: current status and control: a view from the outside.  Cattle Practice.  2005; 13 (4): 305-311.  ISSN:  0969-1251
NAL Call Number:  SF961.C37
Descriptors:  cattle, Mycobacterium bovis, eradication and control concerns, disease levels, UK.

Pollock, J.M.; Skuce, R.A.; Mackie, D.P.; Neill, S.D.  Bovine tuberculosis: research in Northern Ireland.  Cattle Practice.  2005; 13 (4): 301-303.  ISSN:  0969-1251
Descriptors:  badgers (Meles meles), cattle, Mycobacterium bovis, Northern Ireland.  

Pollock, J.M.; Welsh, M.D.; McNair, J.  Immune responses in bovine tuberculosis: towards new strategies for the diagnosis and control of disease.  Veterinary Immunology and Immunopathology.  2005 Oct. 18; 108 (1-2): 37-43.  ISSN: 0165-2427.  Note:  Paper presented at the 7th International Veterinary Immunology Symposium Held July 25-30, 2004, Quebec, Canada.
URL:http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number:  SF757.2.V38
Descriptors:  cattle, bovine tuberculosis, immune response, disease diagnosis, disease control, Mycobacterium bovis, tuberculin, vaccines, diagnostic techniques, disease detection, literature reviews.

Sattelmair, HDie Tuberkulose des Rindes - ein Beitrag zur Geschichte der Haustierkrankheiten[Tuberculosis of the Cattle - A Contribution to the History of Diseases in Domesticated Animals.]  Freie Universitat Berlin. Berlin, Germany.  2005.  211 pp.  Note:  A thesis in German with an English summary.
Descriptors:  historical review, Mycobacterium bovis, cattle, clinical aspects of the disease, pathogenesis, epidemiology, epidemics, disease control, tuberculosis in animals, zoonotic diseases.

Skinner, Margot A.; Wedlock, D. Neil; de Lisle, Geoffrey W.; Cooke, Michßele M.; Tascon, Ricardo E.; Ferraz, Jose C.; Lowrie, Douglas B.; Vordermeier, H. Martin; Hewinson, R. Glyn; Buddle, Bryce M.  The order of prime-boost vaccination of neonatal calves with Mycobacterium bovis BCG and a DNA vaccine encoding mycobacterial proteins Hsp65, Hsp70, and Apa is not critical for enhancing protection against bovine tuberculosis.  Infection and Immunity.  2005; 73 (7): 4441-4444.  ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  Priming neonatal calves at birth with a Mycobacterium bovis bacillus Calmette-Guerin (BCG) vaccine and boosting with a DNA vaccine consisting of plasmids encoding mycobacterial antigens Hsp65, Hsp70, and Apa or the reverse prime-boost sequence induced similar levels of protection against experimental challenge with Mycobacterium bovis.  When M. bovis was isolated from a thoracic lymph node following challenge, the two groups of calves given the prime-boost regimen had significantly lower numbers of M. bovis isolates than those vaccinated with BCG alone.  These observations suggest that the exact sequence of administration of a prime-boost vaccination regimen in a neonatal animal model is not critical to the development of immunity.
Descriptors:  Mycobacterium bovis, neonatal animal model, calves, prime-boost vaccination regimen, development of immunity.

Underwood, S.C.; Carfagnini, J.C.  Comparacion de dos criterios para la interpretacion de la prueba tuberculinica cervical comparativa en caprinos. [Comparison between two criterions to interpret the tuberculin cervical comparative test in caprines.]  Revista Argentina de Produccion Animal. 2005; 25 (3/4): 199-205  ISSN:  0326-0550.  Note: In Spanish with an English summary.
Descriptors:  goats, caprine test, compare test results between cattle and goats, cervical comparative test, OOIE interpretation rules, criterion proposed by Garcia Marin and Gutierrez Cancela, differences were found, Argentina.

Veeregowda, B.M.; Isloor, S.; Leena, G.; Rajsekhar, M.  Assessment of an enzyme linked immunosorbent assay for detection of bovine tuberculosisJournal of Veterinary Public Health. 2005; 3(2): 111-114.  ISSN:  0972-7485
Descriptors:  cattle, Mycobacterium bovis, serum antibody detection, avidin-biotin ELISA, sensitivity and specificity were low, not suitable for a diagnostic tool.

Villarreal-Ramos, B.; McAulay, M.; Reed, S.; Prentice, H.; Coffey, T.; Cherleston, B.; Howard, C.  Effect of the nature of the antigen on the boosting of responses to mycobacteria in M bovis BCG vaccinated cattle.  Immunology.  2005; 116 (Suppl. 1): 22.  ISSN:  0019-2805.  Note:  A meeting abstract.
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0019-2805&site=1
NAL Call Number:  448.3 IM6
Descriptors:  cattle, antibody, antigen, BCG, immunologic drug, immunostimulant drug, vaccine, Mycobacterium bovis infection, bovine tuberculosis, animal pathogens, prevention and control, Th1 cell, immune system, Th2 cell.

Vordermeier, M.; Buddle, B.; Hewinson, R.G.  Development of cattle vaccines against bovine tuberculosis.  Research in Veterinary Science.  2005; 78 (Suppl. A): 11-12.  ISSN:  0034-5288.  Note:  A meeting abstract.  59th Annual Conference of the Association for Veterinary Teaching and Research Work, Scarborough, England; March 21 -23, 2005. 
URL:http://www.elsevier.com/wps/find/journaldescription.cws_home/623070/description#description
NAL Call Number:  41.8 R312
Descriptors:  cattle, Mycobacterium tuberculosis, Mycobacterium bovis, DNA, vaccine antigens, tuberculosis vaccine, immunostimulant drug.

Vordermeier,-M; Goodchild, A; Clifton-Hadley, R; Rua, R. de la.  The interferon-gamma field trial: background, principles and progressCattle Practice.  2005; 13 (4): 323-325.  ISSN:  0969-1251.  Note:  Reprinted from Veterinary Record.  2004; 155: 37-38.
NAL Call Number:  SF961.C37
Descriptors:  cattle, Mycobacterium bovis, diagnosis, diagnostic techniques, disease prevalence, epidemiology, interferon, skin tests, tuberculin test, UK.

Wangoo, A.; Rhodes, S.; Gough, G.; Inglut, S.; Ackbar, R.; Spencer, Y.; Hewinson, R.G.; Vordermeier, M.; Johnson, L.  Low dose Mycobacterium bovis infection in cattle results in pathology resembling to that of high dose infectionResearch in Veterinary Science.  2005; 78 (Suppl. A): 41.  ISSN:  0034-5288 .  Note:  Meeting abstract.  59th Annual Conference of the Association for Veterinary Teaching and Research Work, Scarborough, England; March 21 -23, 2005 
URL:http://www.elsevier.com/wps/find/journaldescription.cws_home/623070/description#description
NAL Call Number:  41.8 R312
Descriptors:  cattle, Mycobacterium bovis, low dose infection, comparison to high dose infection, pathology, etiology, transmission.

Wangoo, A.; Johnson, L.; Gough, J.; Ackbar, R.; Inglut, S.; Hicks, D.; Spencer, Y.; Hewinson, G.; Vordermeier, M.  Advanced granulomatous lesions in Mycobacterium bovis-infected cattle are associated with increased expression of type I procollagen, gamma delta (WC1+) T cells and CD 68+ cells.  Journal of Comparative Pathology.  2005 Nov.; 133 (4): 223-234.  ISSN: 0021-9975
NAL Call Number:  41.8 J82
Descriptors:  granuloma, disease course, gene expression, Mycobacterium bovis, type I procollagen, gamma delta (WC1+) T cells, CD 68+ cells.

Wedlock, D. Neil; Denis, Michel; Skinner, Margot A.; Koach, Jessica; de Lisle, Geoffrey W.; Vordermeier, H. Martin; Hewinson, R. Glyn; van Drunen Little van den Hurk, Sylvia; Babiuk, Lorne A.; Hecker, Rolf; Buddle, Bryce M.  Vaccination of cattle with a CpG oligodeoxynucleotide-formulated mycobacterial protein vaccine and Mycobacterium bovis BCG induces levels of protection against bovine tuberculosis superior to those induced by vaccination with BCG Alone.  Infection and Immunity.  2005; 73 (6): 3540-3546.  ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  The development of a subunit protein vaccine for bovine tuberculosis which could be used either in combination with Mycobacterium bovis BCG (to improve the efficacy of that vaccine) or alone would offer significant advantages over currently available strategies.  A study was conducted with cattle to determine the protective efficacy of a strategy based on concurrent immunization with an M. bovis culture filtrate (CFP) vaccine and BCG compared to vaccination with either vaccine alone.  One group of calves (10 animals per group) was vaccinated subcutaneously with CFP formulated with Emulsigen and combined with a CpG oligodeoxynucleotide (ODN).  A second group was vaccinated with both the CFP vaccine and BCG injected at adjacent sites (CFP-BCG).  One further group was vaccinated subcutaneously with BCG, while another group served as nonvaccinated control animals.  Vaccination with CFP-BCG induced levels of antigen-specific gamma interferon (IFN-[gamma]) and interleukin-2 (IL-2) in whole-blood cultures that were higher than those induced by vaccination with BCG alone.  The combination of CFP and BCG did not enhance the production of antibodies to M. bovis CFP compared to vaccination with CFP alone.  Vaccination with CFP alone led to delayed antigen-specific IFN-[gamma] and IL-2 responses.  Vaccination with CFP-BCG induced a high level of protection against an intratracheal challenge with virulent M. bovis, based on a significant enhancement of six pathological and microbiological parameters of protection compared with the nonvaccinated group.  In contrast, vaccination with BCG alone induced a significant enhancement of protection in only one parameter, while CFP alone induced no protection.  These results suggest that a combination of a CpG ODN-formulated protein vaccine and BCG offers better protection against bovine tuberculosis than does BCG alone.
Descriptors:  bovine tuberculosis, subunit protein vaccine, development, Mycobacterium bovis, culture filtrate-based vaccine, BCG vaccine, calves, experimental model, efficacy of several regimens.

Wedlock, D.N.; Skinner, M.A.; De Lisle, G.W.; Vordermeier, H.M.; Hewinson, R.G.; Hecker, R.; Van Drunen-Little van den Hurk, S.; Babiuk, L.A.; Buddle, B.M.  Vaccination of cattle with Mycobacterium bovis culture filtrate proteins and CpG oligodeoxynucleotides induces protection against bovine tuberculosis.  Veterinary Immunology and Immunopathology.  2005; 106 (1-2) 53-63.  ISSN: 0165-2427
URL: http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number:  SF757.2.V38
Descriptors:  cattle, Mycobacterium bovis, bovine tuberculosis, vaccination, culture filtrates, nucleotide sequences, disease prevention, vaccine adjuvants, immunomodulators, immune response, organic acids and salts, granulocyte macrophage colony stimulating factor, recombinant proteins, interferons, cell mediated immunity, bacterial antigens, subunit vaccines, molecular sequence data, CpG islands, polyinosinic acid, polycytidylic acid.

Welsh, Michael D.; Cunningham, Rodat T.; Corbett, David M.; Girvin, R Martyn; McNair, James; Skuce, Robin A.; Bryson, David G.; Pollock, John M.  Influence of pathological progression on the balance between cellular and humoral immune responses in bovine tuberculosis.  Immunology.  2005; 114 (1): 101-111.  ISSN:  0019-2805.  Online ISSN:  1365-2567
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0019-2805&site=1
NAL Call Number:  448.3 IM6
Descriptors:  cattle, Mycobacterium bovis, supressed cell-mediated immune responses, and increased humoral responses, study on balance of evolving immune responses, pathogenesis, CD4 T-cell clones, increased ratio of Th0 [interleukin-4-positive/interferon-gamma-positive (IL-4(+)/IFN-gamma(+))] clones to Th1 (IFN-gamma(+)) clones.

Whelan, A.O.; Coad, M.; Cockle, P.J. Hewinson, R.G. Gordon, S; Vordermeier, H.M.  Comparative virulence and immunology of M. tuberculosis and M. bovis in cattleImmunology.  2005; 116 (Suppl. 1): 77.  ISSN:  0019-2805.  Note:  Abstract, Annual Congress of the British Society for Immunology, Harrogate, England; December 06 -09, 2005
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0019-2805&site=1
NAL Call Number:  448.3 IM6
Descriptors:  cattle, humans, zoonotic diseases, bacterial pathogens, Mycobacterium tuberculosis Rv3879c-gene, Mycobacterium bovis Rv3879c gene, interferon-gamma; antigen, PPD, ESAT6, CFP10.

Winthrop, K.L.; Scott, J.; Brown, D; Jay, M.T.; Rios, R.; Mase, S.; Richardson, D.; Edmonson, A.; MacLean, M.; Flood, J.  Investigation of human contacts: a Mycobacterium bovis outbreak among cattle at a California dairy.  International Journal of Tuberculosis and Lung Disease.  2005; 9 (7): 809-813.  ISSN:  1027-3719.  Note:  In English with summaries in French and Spanish.  
Descriptors:  dairy cattle, Mycobacterium bovis, dairy farms, occupational health study, working with infection animals, drinking raw milk, dairy workers, families, slaughterhouse workers, tuberculin skin test, disease-transmission; Mexican-American ethnic groups, human diseases milk-borne diseases, outbreaks, risk factors, tuberculosis, zoonoses, California, US.

Woodroffe, R.; Donnelly, C.A.; Johnston, W.T.; Bourne, F.J.; Cheeseman, C.L.; Clifton-Hadley, R.S.; Cox, D.R.; Gettinby, G.; Hewinson, R.G.; Le Fevre, A.M.  Spatial association of Mycobacterium bovis infection in cattle and badgers Meles meles.  Journal of Applied Ecology.  2005 Oct 42 (5 ): 852-862.  ISSN: 0021-8901
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0021-8901&site=1
NAL Call Number:  410 J828
Descriptors:  cattle, badgers (Meles Meles), Mycobacterium bovis, bovine tuberculosis, strains, zoonoses, spatial distribution, disease prevalence, disease reservoirs, disease transmission, disease control, cluster analysis, Great Britain.

Woolhouse, M.E.J.  Dangers of moving cows.  Nature.  2005; 435 (7041): 431-432.  ISSN: 0028-0836
URL:  http://www.nature.com/index.html.
NAL Call Number:  472 N21
Descriptors:  cattle, bovine tuberculosis, Mycobacterium bovis, animal transport, movement of animals, geographical distribution, disease transmission, badgers, epidemiology, Great-Britain.

Zanini, M.S.; Moreira, E.C.; Salas, C.E.; Lopes, M.T.P.; Barouni, A.S.; Roxo, E.; Telles, M.A.; Zumarraga, M.J.  Molecular typing of Mycobacterium bovis isolates from south-east Brazil by spoligotyping and RFLP.  Journal of Veterinary Medicine  Series B.  2005 Apr; 52 (3) 129-133.  ISSN: 0931-1793
NAL Call Number:  41.8 Z52  
Descriptors:  dairy cattle, beef cattle, bovine tuberculosis, Mycobacterium bovis, pathogen identification, microbial genetics, strains, genetic polymorphism, molecular genetics, antibiotic resistance, diagnostic techniques, spoligotyping, ethionamide rifampicin, isoniazid, strain differences, disease surveillance, diagnostic-techniques, post slaughter tissue collection, identification of 163 strains, polymerase chain reaction (PCR) and microbiological tests, 252 tuberculous-like lesions, 3 genotyping techniques, IS6110-restriction fragment length polymorphism (RFLP), polymorphic guanine-cytosine-rich sequence (PGRS)-RFLP and direct repeat (DR)-spoligotyping, fails to show a correlation between main cluster found by the 3 techniques, Brazil.

2004

Allsopp, B.A.; Babiuk, L.A.; Babiuk, S.L.  Vaccination: an approach to the control of infectious diseases.   In:  J.A.W. Coetzer and R. C. Tustin (editors).  Infectious Diseases of Livestock, Volume One.  2004; (Ed.2):  Oxford University Press, Oxford, UK.  2004: 239-247.  ISBN: 01915761693. Note:  A book chapter.
Descriptors:  livestock animals, animal diseases, Escherichia coli, Listeria monocytogenes, Mycobacterium bovis, disease control measures, vaccination, live vaccines, DNA vaccines, inactivated vaccines,  BCG vaccines, passive immunization, disease prevention and control.

Asseged, B.; Woldesenbet, Z.; Yimer, E.; Lemma, E.  Evaluation of abattoir inspection for the diagnosis of Mycobacterium bovis infection in cattle at Addis Ababa abattoir.  Tropical Animal Health and Production. 2004; 36 (6): 537-546.  ISSN: 0049-4747.  Note:  In English with summaries in French and Spanish.
URL: http://www.springerlink.com/content/103008/
NAL Call Number:  SF601-.T7
Descriptors:  cattle, Mycobacterium bovis, slaughter, meat inspection, bovine tuberculosis, Ethiopia.

Baptista, F.; Moreira, E.C.; Santos, W.L.M.; Naveda, L.A.B.  Prevalencia da tuberculose em bovinos abatidos em Minas Gerais.  [Prevalence of tuberculosis in cattle slaughtered in Minas Gerais, Brazil.]  Arquivo Brasileiro de Medicina Veterinaria e Zootecnia.  2004; 56 (5): 577-580.  ISSN:  0102-0935.  Note:  In Portuguese with an English summary.
Descriptors: humans, slaughter cattle survey, Mycobacterium bovis disease levels, disease prevalence, epidemiology, geographical distribution, zoonoses, Minas Gerais, Brazil.

Belgium Federal Agency for the Safety of the Food Chain.  Report on Zoonotic Agents in Belgium 2003: Working Group on Foodborne Infections and Intoxications.  Published by the Federal Agency for the Safety of the Food Chain (FASFC).  Brussels.  2004; 74 pp.
Descriptors:  common disease agents, domestic and wild animals, zoonotic potential, Mycobacterium bovis, Brucella melitensis, Brucella abortus, Brucella suis, Salmonella spp., Trichinella spp., rabies virus, Campylobacter spp., Echinococcus granulosus, Echinococcus multilocularis, Listeria monocytogenes, Yersinia enterocolitica, verotoxin producing Escherichia coli O157:H7, Taenia saginata, Sarcocystis hominis, Sarcocystis suihominis, Toxoplasma gondii, food borne illness, clinical aspects, routes of infection, recommendations, numbers of animals slaughtered in 2003, Belgium.

Bengis, R.G.; Kock, R.A.; Thomson, G.R.; Bigalke, R.D.  Infectious diseases of animals in sub-Saharan Africa: the wildlife/livestock interface.  In: J.A.W. Coetzer and R.C. Tustin (editors).  Infectious Diseases of Livestock, Volume One.  2004; (Ed.2).  Oxford University Press.  Oxford.  2004:  225-238.  ISBN:  01915761693.  Note:  A book chapter.
Descriptors:  cattle, goats, pigs, horses, dogs, wildlife diseases, ruminants, Syncerus caffer, animal diseases, epidemics, African horse sickness, African swine fever, anthrax, brucellosis, epidemiology, foot and mouth disease, bovine tuberculosis, malignant catarrhal fever, rabies, Rift Valley fever, rinderpest, trypanosomiasis, etc.

Collins, J.D.; Wall, P.G.  Food safety and animal production systems: controlling zoonoses at farm level.  Revue Scientifique et Technique Office International des Epizooties.  2004; 23 (2): 685-700.  ISSN:  0253-1933.  ISBN:  9290446218.  Note:  In English with Spanish and French summaries
Descriptors:  Brucella abortus, Campylobacter, Escherichia coli, Listeria monocytogenes, Mycobacterium avium ssp paratuberculosis, Mycobacterium bovis, Salmonella, Toxoplasma, Trichinella spiralis, Yersinia enterocolitica, abortion, animal production, disease control, disease prevention, epidemiology, feeds, food chains, food contamination, food safety, hygiene, paratuberculosis, risk assessment, selection pressure; stress to animals in transport, tuberculosis, zoonoses.

Cvetnic, Z.; Spiic, S.; Katalinic-Jankovic, V.; Capek, B.; Habrun, B.; Mitak, M.  Primjena metode DNK u dijagnostici i identifikaciji kompleksa Mycobacterium tuberculosis u domacih zivotinja. [Application of a DNA method for the diagnosis and identification of Mycobacterium tuberculosis complex in domestic animals.]  Veterinarska Stanica.  2004; 35 (5/6): 261-268.  ISSN:  0350-7149.  Note:  In Croatian with an English summary.  
Descriptors:  cows, pigs, tuberculosis, clinical aspects, animal slaughtered, Mycobacterium bovis, Mycobacterium spp., diagnosis, multiplication of DNA sequence of the gene coding 65kD antigen, PCR, Croatia, Yugoslavia, Serbia, Montenegro.

Diguimbaye, C.; Schelling, E.; Pfyffer, G.E.; Baggi, F.; Ngandolo, R.; Ndoutamia, G.; Tanner, M.; Zinsstag, J.  Premiers isolements de mycobacteries tuberculeuses chez l'homme et l'animal au Tchad.  [First isolation of tuberculous mycobacteria in man and animals in Chad.]  Medecine Tropicale.  2004; 64 (5): 482-485.  ISSN:  0025-682X.  Note:  In French with an English summary.
Descriptors:  first isolation and identification of Mycobacterium bovis, Mycobacterium tuberculosis, antibiotic resistance, pyrazinamide, control policies needed, Chad.

Erler, W.; Martin, G.; Sachse, K.; Naumann, L.; Kahlau, D.; Beer, J.; Bartos, M.; Nagy, G.; Cvetnic, Z.; Zolnir-Dovc, M.; Pavlik, I.  Molecular fingerprinting of Mycobacterium bovis subsp. caprae isolates from Central Europe.  Journal of Clinical Microbiology.  2004; 42 (5): 2234-2238.  ISSN:  095-1137
URL:  http://jcm.asm.org/cgi/content/short/42/5/2234
Descriptors:  cattle, humans, Mycobacterium bovis ssp caprae, 79 European isolates, dissemination of pathogen, spoligotyping, ES6110 RFLP analysis, type C1 predominant, 11 different spoligotypes, 43 different RFLP types identified, DNA fingerprinting, zoonotic diseases.

Fritsche, A.; Engel, R.; Buhl, D.; Zellweger, J.P.  Mycobacterium bovis tuberculosis: from animal to man and back.  International Journal of Tuberculosis and Lung Disease.  2004; 8 (7): 903-904.  ISSN:  1027-3719.  Note:  In English with French and Spanish summaries.  
Descriptors:  humans, cattle, other infected animals, Mycobacterium bovis, strains, zoonotic disease, disease transmission from animal to human and back to animal, case reports, clinical aspects, disease course, disease transmission, exposure, human diseases, strains, tuberculosis, Switzerland.

Gormley, E.; Doyle, M.B.; McGill, K.; Costello, E.; Good, M.; Collins, J.D.  The effect of the tuberculin test and the consequences of a delay in blood culture on the sensitivity of a gamma-interferon assay for the detection of Mycobacterium bovis infection in cattle.  Veterinary Immunology and Immunopathology.  2004; 102 (4): 413-420.  ISSN: 0165-2427
URL: http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number:  SF757.2.V38
Descriptors:  cattle, tuberculin testing, Mycobacterium bovis, gamma interferon assay, detection of Mycobacterium bovis, blood culture.

Gunn-Moore, D.  Investigating feline tuberculosis.  Veterinary Times.  2004; 34 (13): 10.  ISSN:  1352-9374
Descriptors:  cats, cattle, humans, Mycobacterium avium, Mycobacterium bovis, Mycobacterium microti, disease prevalence, disease transmission between species, epidemiology, risk factors, disease spread, zoonoses.

Joardar, S.N.; Ram, G.C.; Goswami, T.K.  Kinetics of seroreactivity of Mycobacterium bovis AN5 culture filtrate antigens in experimental bovine tuberculosis.  Indian Journal of Animal Health.  2004; 43(1): 19-26.  ISSN:  0019-5057
Descriptors:  Mycobacterium bovis AN5, serodiagnosis, kinetics of seroreactivity, cattle, experimental infection, antibody level/titre, ELISA, 0-45 days post inoculation, sensitized animals, Western blot analysis, various polypeptide weights, immunodominant polypeptides.

Jordao Junior, C.M.  Mycobacteria research in water buffalo milk.  Revista do Instituto Adolfo Lutz.  2004; 63 (2): 273.  ISSN:  0073-9855
Descriptors:  water buffalo, Bubalus bubalis, milk products, microflora in milk, humans, zoonotic diseases, Mycobacterium intracellulare, Mycobacterium simiae, Mycobacterium bovis, strain JI321 e JB22, strain INS eINS2, strain AN5, Mycobacterium flavenscens.

Katoch, R.C.; Madhumeet Singh; Subhash Verma; Gupta, V.K.; Mandeep Sharma; Vineeta Almadi.  Genital tuberculosis in a Jersey crossbred cow.  Indian Veterinary Journal.  2004; 81(2): 216-217.  ISSN:  0019-6479
NAL Call Number:  41.8 IN2
Descriptors:  cattle, Jersey cross bred cow, Mycobacterium bovis, Staphylococcus aureus, genital area lesions, histopathology, diagnosis mixed infections, case reports, clinical aspects, Himachal Pradesh, India.

Koo, Hye Cheong; Park, Yong Ho; Ahn, Jongsam; Waters, W. Ray; Hamilton, Mary Jo; Barrington, George; Mosaad, Abdelaziz A.; Palmer, Mitch V.; Shin, Sang; Davis, William C.  New latex bead agglutination assay for differential diagnosis of cattle infected with Mycobacterium bovis and Myobacterium avium subsp. paratuberculosisClinical and Diagnostic Laboratory Immunology.  2004; 11 (6): 1070-1074.  ISSN:  1071-412X
Descriptors: cattle, identification of animals infected with Mycobacterium bovis, Mycobacterium avium ssp. paratuberculosis, current assays not sensitive and specific to identify diseased animals, latex bead agglutination assay (LBAA) using specific immunodominant epitope (ESAT6-p) of M. bovis, compared assay to culture method and skin test, experimental infection and non-infected animals, species specific diagnosis, sera testing, data suggest a rapid, sensitive and specific assay can be developed.

Larson, Jean A.; Animal Welfare Information Center (U.S.).  Tuberculosis in animals : Mycobacterium bacilli that cause devastating zoonotic diseases in many animals.  AWIC Resource Series; no. 2004-01.  U.S. Dept. of Agriculture, Agricultural Research Service, National Agricultural Library, Animal Welfare Information Center.  Beltsville, MD [2004]  
URL: http://www.nal.usda.gov/awic/pubs/TB/TBMain.htm
NAL Call Number:  aHV4701.A94 no. 2004-01
Abstract:  The focus of this publication is on information related to tubercular diseases of animals caused by the bacterial genus Mycobacterium.  Livestock diseases are mostly caused by Mycobacterium bovis and the Mycobacterium tuberculosis complex.  Many species of animals are included: large ruminants, wildlife, wild animals as disease reservoirs, deer, elephants, birds, fish, etc.  Topics are varied and include clinical aspects of the disease, the disease process, disease prevention and control, vaccines, immunology, bacterial genetics, zoonotic aspects, etc.

Diseases:  tuberculosis in animals, bibliography, Mycobacterium sp, Mycobacterium avium, Mycobacterium bovis, zoonoses, production animals, zoo animals, wild animals, disease control, Mycobacterium tuberculosis complex, microbial genetics, disease incidence worldwide, control programs worldwide, immune response, wild animal vectors, treatments, animal disease models, aquatic animals, diagnostic methods, disease pathology, disease incidence worldwide.

Laval, G.; Ameni, G.  Prevalence of bovine tuberculosis in zebu cattle under traditional animal husbandry in Boji district of western Ethiopia.  Revue de Medecine Veterinaire. 2004; 155 (10): 494-499.  ISSN:  0035-1555.  Note:  In English with an English summary.  
Descriptors:  zebu cattle, 62 herds, 780 individuals, animal prevalence, Mycobacterium bovis, single intradermal tuberculin test, comparative intradermal tuberculin test, risk of transmission to humans, Boji district, Ethiopia.

Lucca, E.; Canal, A.M.; Pachoud, J.C.; Gollan, A.; Bergamasco, M.; Latini, M.; Lopez, M.; Nicola, A.; Tomatis, I.; Scarpin, V.  Diagnostico de tuberculosis bovina: correlacion entre pruebas diagnosticas.  [Diagnosis of bovine tuberculosis: correlation between different diagnostic tests.]  Veterinaria Argentina.  2004; 21 (203): 196-203.  ISSN:  0326-4629.  Note:  In Spanish with an English summary.  
Descriptors:  dairy cattle; Mycobacterium bovis; blood sampling, diagnostic tests; correlation between tuberculin skin test, bacteriological cultures, microscopic lesions of lymph nodes and other organs, and interferon-gamma assay; interferon-gamma assay not sufficient at detecting M. bovis, Argentina.

Lutze-Wallace, C.; Chen, S.; Turcotte, C.  Laboratory diagnosis of bovine tuberculosis in Canada for calendar year 2003.  Canadian Veterinary Journal.  2004; 45(11): 915-916.  ISSN:  0008-5286
URL:  http://www.pubmedcentral.nih.gov/tocrender.fcgi?action=archive&journal=202
NAL Call Number:  41.8 R3224
Descriptors:  cattle, bison, pigs, diagnosis, disease prevalence, disease surveys, epidemiological surveys, epidemiology, laboratory diagnosis, tuberculosis, wild animals, zoo animals, Mycobacterium avium subsp avium, Mycobacterium flavescens, Mycobacterium gordonae, Mycobacterium triviale, Cervus elaphus Canadensis, red deer, fallow deer, Mycobacterium avium, Mycobacterium avium subsp paratuberculosis, Mycobacterium bovis, Mycobacterium chelonae, Mycobacterium fortuitum, Mycobacterium marinum, Mycobacterium terrae, Mycobacterium xenopi, Odocoileus virginianus, pigs, Canada.

Lyashchenko, K.; Whelan, A.O.; Greenwald, R.; Pollock, J.M.; Andersen, P.; Hewinson, R.G.; Vordermeier, H.M.  Association of tuberculin-boosted antibody responses with pathology and cell-mediated immunity in cattle vaccinated with Mycobacterium bovis BCG and infected with M. bovis.  Infection and Immunity.  2004; 72 (5): 2462-2467.  ISSN:  0019-9567
URL:  http://iai.asm.org/cgi/content/full/72/5/2462
NAL Call Number:  QR1 I57
Abstract:  Vaccine development and our understanding of the pathology of bovine tuberculosis in cattle would be greatly facilitated by definition of the immunological correlates of protection and/or pathology.  In this study we analyzed humoral immune responses in Mycobacterium bovis BCG-vaccinated and control cattle (in particular, the relationship between the intradermal comparative tuberculin skin test and serum immunoglobulin G [IgG] responses) against a range of mycobacterial antigens (MPB59, MPB64, MPB70, MPB83, ESAT-6, CFP-10, Acr1, and PstS-1) by multiantigen print immunoassay and conventional enzyme-linked immunosorbent assay.  Following M. bovis infection, the comparative tuberculin skin test strongly boosted IgG, IgG1, and IgG2 antibody responses, particularly against MPB83 and MPB70, in unvaccinated cattle but failed to boost these responses, or did so only weakly, in BCG-vaccinated calves. In addition, the skin test-induced increases in MPB83-specific IgG responses correlated positively with bacterial loads and ESAT-6-induced in vitro gamma interferon responses.  In conclusion, both the negative correlation of skin test-enhanced MPB83-specific antibody responses with BCG-induced protection and their positive correlation with bacterial loads can serve as useful markers for vaccine efficacy after challenge.
Descriptors:  cattle, Mycobacterium bovis, experimental infections, immune response, antibodies, antigens, cell mediated immunity, humoral immunity, IgG, immunization, interferon, tuberculin skin tests, vaccination, vaccines.

Mackintosh, C.G.; Lisle, G.W. de; Collins, D.M.; Griffin, J.F.T.  Mycobacterial diseases of deer.  New Zealand Veterinary Journal.  2004; 52 (4): 163-174.  ISSN:  0048-0169
URL:  http://www.vetjournal.org.nz/nzvet.html
NAL Call Number:  41.8 N483
Descriptors:  captive farmed deer, Mycobacterium avium complex, Mycobacterium avium subsp paratuberculosis, Mycobacterium bovis, diagnosis, disease prevention and control, epidemiology, mycobacteria diseases, zoonotic diseases, paratuberculosis, literature reviews, New Zealand.

Magnano, G.; Urbani, C.; Schneider, M.; Giraudo, J.  Tuberculosis caprina: comparacion entre animales positivos a la prueba de intradermorreaccion y la presencia de lesiones y/o aislamiento.  [Tuberculosis in goats: comparison between positivity to the skin test, pathological lesions and bacteriological cultures.]  Veterinaria Argentina.  2004; 21 (208): 570-576.  ISSN:  0326-4629.  Note:  In Spanish with an English summary.  
Descriptors:  goats, Mycobacterium bovis, diagnostic testing, diagnostic techniques, disease survey, disease prevalence, reliability of skin tests, postmortem tissue sampling, in vitro culture, comparison study, animal pathology, Argentina.

Maue, Alexander C.; Waters, W. Ray; Palmer, Mitchell V.; Whipple, Diana L.; Minion, F. Chris; Brown, Wendy C.; Estes, D. Mark.  CD80 and CD86, but not CD154, augment DNA vaccine-induced protection in experimental bovine tuberculosis.  Vaccine.  2004; 23 (6): 769-779.  ISSN:  0264-410X
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/30521/description#description
Descriptors:  cattle,  enhancing immune response, Mycobacterium bovis BCG, vaccination, aerosol challenge with virulent M. bovis, co stimulatory molecules, CD154, CD80, CD86, CpG-ODN, DNA vaccination, anti-infective drug, adverse effects, efficacy, intravenous administration; subunit DNA vaccine ESAT-6, interferon-gamma, disease prevention and control.  

McCorry, T.P.; McCormick, C.M.; Hughes, M.S.; Pollock, J.M.; Neill, S.D.  Mycobacterium nonchromogenicum in nasal mucus from cattle in a herd infected with bovine tuberculosis.  Veterinary Microbiology.  2004; 99 (3/4): 281-285.  ISSN:  0378-1135
URL: http://www.elsevier.com/wps/find/journaldescription.cws_home/503320/description#description
NAL Call Number:  SF601.V44
Descriptors:  cattle herds, Mycobacterium nonchromogenicum, Mycobacterium bovis, genotypes, nucleotide sequences, skin tests, blood sampling, antibody ELISA, interferon-gamma assay, radiometric culture of nasal mucus samples, DNA probe testing Accuprobe, M. tuberculosis PCR amplification, 16S rRNA PCR, sequence analysis, first report of M. nonchromogenicum in nasal mucus of cattle, zoonotic risks.

McKenzie, J.S..; Morris, R.S.; Pfeiffer, D.U.; Meenken, D.; Lambie, J.  Application of GIS and landscape epidemiology to TB control in possums.  GISVET' 04: Second International Conference on the Applications of GIS and Spatial Analysis to Veterinary Science, University of Guelph, Ontario, Canada, 23rd 25th June. 2004: 78-80.  ISBN:  189951323X.  Note:  Published by Veterinary Laboratories Agency.  Addlestone, UK
Abstract:  The EpiCentre, of Massey University used a farm level land forms survey epidemiological techniques to identify habitat and topographic risk factors associated with the distribution of TB infected possum clusters, of residual possums following culling and possum TB risk.  These results were to develop geographic models within a GIS using satellite-derived habitat data to facilitate a risk-based approach to TB management in New Zealand.
Descriptors:  cattle, Mycobacterium bovis; brushtail possum (Trichosurus vulpecula), disease surveillance methods, wildlife disease reservoir, epidemiology, geographic information systems, GIS, New Zealand.

Mirsojev, D.M.; Drauschke, W.  Spread of tuberculosis in cattle stocks in various areas of Tajikistan.  Journal of Agriculture and Rural Development in the Tropics and Subtropics.  2004; 105 (2): 197-200.  ISSN:  0041-3186.  Note:  In Russian with an English summary.  
Descriptors:  cattle, tuberculosis levels 1943-1994, Mycobacterium bovis, inadequate veterinary measures, insufficient diagnosis of cattle, lack of long term control of infected animals, disease prevention and control at the farm level, sanitation practices improved, zoonotic risks of transmission to humans, Republic of Tajikistan.

Mota, P.M.P.C.; Motta, P.M.C.; Lobato, F.C.F.; Lage, A.P.; Ribeiro, A.C.C.L.; Leite, R.C.  Avaliacao do tratamento com isoniazida em bovinos infectados naturalmente pelo Mycobacterium bovis.  [Evaluation of isoniazid treatment carried in cattle naturally infected with Mycobacterium bovis.]  Arquivo Brasileiro de Medicina Veterinaria e Zootecnia.  2004; 56 (5): 581-588.  ISSN:  0102-0935.  Note:  In Portuguese with an English summary.  
Descriptors:  naturally infected cattle herd, 240 animals, humans, Mycobacterium bovis, intermittent drug treatment, isoniazid, oral dosing 3x/week, zoonotic disease.

Nita, C.  Diagnosticul tuberculozei la bovine in judetul Vaslui prin testul imunoenzimatic-procedeul sandwich pentru detectarea gamma-interferonului.  [The diagnosis of bovine tuberculosis in Vaslui District by an enzyme immunoassay for detection of gamma-interferon.]  Revista Romana de Medicina Veterinara.  2004; 14 (3): 149-154.  ISSN:  1220-3173.  Note:  In Romanian with an English summary.  
Descriptors:  cattle, testing intradermal reaction, enzyme immunoassay follow up, gamma interferon, in vitro stimulated blood samples, diagnostic techniques, disease prevalence and control, Mycobacterium bovis, epidemiology, Strategic program for Supervision and Control of Bovine Tuberculosis, Vaslui District, Romania.

Norby, B.; Bartlett, P.C.; Fitzgerald, S.D.; Granger, L.M.; Bruning-Fann, C.S.; Whipple, D.L.; Payeur, J.B.  The sensitivity of gross necropsy, caudal fold and comparative cervical tests for the diagnosis of bovine tuberculosis.  Journal of Veterinary Diagnostic Investigation.  2004; 16 (2): 126-131.  ISSN:  1040-6387
URL:  http://jvdi.org/
NAL Call Number:  SF774.J68
Descriptors:  22 cattle herds, Mycobacterium bovis, complement fixation tests, diagnosis, diagnostic techniques, diagnostic value of several tests, gross necropsy, histological exam, mycobacterial culture, PCR assay of samples suspected of bTb, sensitivity of caudal fold and comparative cervical skin tests, tests compared, disease control, culling, depopulation, zoonoses, northeast corner of Michigan’s lower peninsula.

Palmer, M.V.; Waters, W.R.; Whipple, D.L.; Slaughter, R.E.; Jones, S.L.  Evaluation of an in vitro blood-based assay to detect production of interferon-gamma by Mycobacterium bovis-infected white-tailed deer (Odocoileus virginianus).  Journal of Veterinary Diagnostic Investigation.  2004; 16 (1): 17-21.  ISSN:  1040-6387
URL:  http://jvdi.org/
NAL Call Number:  SF774.J68
Descriptors:  deer (Odocoileus virginianus), Mycobacterium bovis, captive Cervidae added to the USDA Uniform Methods and Rules for eradication of bovine tuberculosis, wild animals as a disease reservoir, testing potential of a new blood-based assay for Cervidae, animal welfare, reduced handling, stress and injury and death, experimental inoculation, 300 colony forming units. tonsillar crypts, young males and females, serial blood collection up to 307 days, analyzed for production of  M. bovis, PPDb, M. avium PPDa, pokeweed mitogen or media alone, PPDb may serve diagnostic technique ante mortem, Michigan.

Pate, Mateja; Zdovc, Irena; Pirs, Tina; Krt, B.; Ocepek, M.  Isolation and characterisation of Mycobacterium avium and Rhodococcus equi from granulomatou lesions of swine lymph nodes in Slovenia.  Acta Veterinaria Hungarica.  2004; 52 (2): 143-150. ISSN:  0236-6290
Descriptors:  cattle, swine, lymph nodes, mixed infections, Mycobacterium hominissuis (IS901-, IS1245+ genotype), Mycobacterium avium avium (IS901+, IS1245+ genotype), typed using IS1245, IS901 and FR300 PCR, Rhodococcus equi isolates, tested for virulence-associated antigens (VapA and VapB).

Pavlik, I.; Jahn, P.; Dvorska, L.; Bartos, M.; Novotny, L.; Halouzka, R.  Mycobacterial infections in horses: a review of the literature.  Veterinarni Medicina.  2004; 49 (11): 427-440.  ISSN:  0375-8427
Descriptors:  horses, mycobacterial infections, Mycobacterium avium complex, Mycobacterium tuberculosis, Mycobacterium avium ssp paratuberculosis, Mycobacterium bovis, Mycobacterium chelona, Mycobacterium fortuitum, Mycobacterium smegmatis, Mycobacterium terrae, Mycobacterium africanum, Mycobacterium microti, clinical signs, epidemiological relationships, atypical disease course, diagnosis, diagnostic techniques, disease-prevalence, disease transmission, epidemiology, histopathology, molecular genetics, risk-factors, serotypes, taxonomy, zoonoses, literature review, seen in Central Europe.

Perez, A; Debenedetti, R; Martinez-Vivot, M; Bernardelli, A.; Torres, P.; Ritacco, V.  Tendencia de la tuberculosis porcina y validez de la inspeccion bromatologica para su deteccion en areas de produccion intensiva de la Argentina.  [Swine tuberculosis in Argentina: the value of the bromatologic inspection in an intensive swine production area.]  Revista de Medicina Veterinaria Buenos Aires.  2004; 85 (2): 61-64.  ISSN:  0325-6391.  Note:  In Spanish with an English summary.  
Descriptors: pigs, intensive production systems, Mycobacterium bovis, diagnosis, disease prevalence, disease control, post slaughter examinations, abattoirs, carcass condemnation, carcasses, disease control, disease surveys, disease transmission, epidemiology, histopathology, monitoring, Argentina.

Pun, M.B.; Prasai, T.P.; Mermagya-Dhakal; Jha, V.K.; Shrestha, K.B.; Jha, V.C.; Sato, T.; Morita, Y.; Kozawa, K.; Kimura, H.  Single intradermal tuberculin tests of milking buffaloes and cows in Nepal.  Veterinary Record (London). 2004; 154 (4): 124.  ISSN:  0042-4900
URL:
http://veterinaryrecord.bvapublications.com/

NAL Call Number:  41.8 V641
Descriptors:  buffalo, cattle, cows, humans, Mycobacterium bovis, Mycobacterium tuberculosis, Mycobacterium africanum, Mycobacterium canetti, Mycobacterium microti, disease prevalence, disease transmission from animals to humans, zoonotic aspects, intradermal tuberculin test.

Retamal, P.I.; Abalos, P.E.  Comparacion del ensayo de interferon gamma bovino con tecnicas tradicionales para el diagnostico de infeccion con Mycobacterium bovis en la Region Metropolitana de Chile.  [Comparison of the bovine gamma-interferon assay with traditional techniques for detecting infection with Mycobacterium bovis.]  Revista Colombiana de Ciencias Pecuarias.  2004; 17(3): 223-230.  ISSN:  0120-0690.  Note: In Spanish with an English summary.
Descriptors:  cattle, bovine tuberculosis, Mycobacterium bovis, assays, detection, diagnosis, diagnostic techniques, interferon.

Ritelli, M.; Amadori, M.; Dondo, A.; Begni, B.; Zoppi, S.; Archetti, I.L.  Combined use of the g-interferon and interleukin-2 receptor assays for diagnosis of bovine tuberculosis.  Online Journal of Veterinary Research.  2004; 8: 16-21.  ISSN:  1328-925X
Abstract:  The g-interferon assay for bovine tuberculosis has reached wide acceptance in many countries.  Yet, less than optimal specificity in some areas and a certain percentage of inconclusive results may affect this diagnostic technique.  The problem of inconclusive results can be approached by a two-stage procedure, whereby peripheral blood mononuclear cells of g-interferon dubious samples are later analysed for expression of the interleukin-2 receptor; this had been validated as a further alternative marker of cell-mediated immunity in M. bovis-infected cattle.  This way, the two assays are used sequentially on the same blood samples.  As a result, further diagnostic information can be obtained without new blood samplings in the field.  The results of the interleukin-2 receptor assay showed a high correlation with those of the g-interferon assay.  Instead, there was no clear evidence of increased specificity under the conditions reported in this study.
Descriptors:  cattle, Mycobacterium bovis, blood sampling, peripheral blood monomuclear cells, diagnostic assay, cell mediated immunity g-interferon, interleukin-2.

Scantlebury, M.; Hutchings, M.R.; Allcroft, D.J.; Harris, S.  Risk of disease from wildlife reservoirs: badgers, cattle, and bovine tuberculosis.  Journal of Dairy Science.  2004; 87 (2): 330-339.  ISSN: 0022-0302
URL:  http://jds.fass.org/contents-by-date.0.shtml
NAL Call Number:  44.8 J822
Descriptors:  dairy cows, disease-reservoirs, wildlife livestock relations, badgers, Meles meles, Mycobacterium bovis, cattle grazing intensity, rotational grazing, strip grazing, animal behavior, risk assessment, England.

Shkaeva, N.A.  Spread of bovine tuberculosis in a radiocontaminated area of Chelyabinsk Oblast.  Russian Agricultural Sciences.  2004; (4): 30-32.  ISSN:  1068-3674.  Note:  Translated from Doklady Rossiiskoi Akademii Sel'skokhozyaistvennykh Nauk (2004) No. 2: 41-43 (Ru).  Publisher is AllertonPress, Inc, NY, NY
Descriptors:  cattle, bovine tuberculosis, Mycobacterium bovis, relationship between epizootic situation and local radioactive waste contamination, soil pollution, study 1984-2002, high level of disease, remedial measures taken, positive relationship between disease and contamination, Russia.

Singh, B.B.; Sharma, S.; Kumar, H.; Dhand, N.K.  Surveillance of diseases in organized dairy farms of Punjab.  Journal of Research, Punjab Agricultural University.  2004; 41 (4): 490-494.  ISSN:  0048-6019.  
Descriptors:  3 dairy cattle farms, health status monitoring, disease prevalence, various diseases, brucellosis, infectious bovine rhinotracheitis, bovine tuberculosis 2.13%, Johne’s disease, theileriosis, trypanosomiasis, babesiosis, disease prevention, various disorders mentioned, Punjab, India.

Singh, S.K.; Rishendra Verma; Shah, D.H.  Molecular fingerprinting of clinical isolates of Mycobacterium bovis and Mycobacterium tuberculosis from India by restriction fragment length polymorphism (RFLP).  Journal of Veterinary Science.  2004; 5 (4): 331-335.  ISSN:  1229-845X
Descriptors:  humans, animals, Mycobacterium bovis, Mycobacterium tuberculosis, disease transmission between species, 40 mycobacterial strains, clinical and field isolates, RFLP, IS6110 and IS1081 probes, dairy cattle herds, patients, Indian Veterinary Research Institute campus, strains and species compared, India.

Smith, Robert M.M.; Drobniewski, Francis; Gibson, Andrea; Montague, John D.E.; Logan, Margaret N.; Hunt, David; Hewinson, Glyn; Salmon, Roland L.; O'Neill, Brian.  Mycobacterium bovis infection, United Kingdom.  Emerging Infectious Diseases.  2004; 10 (3): 539-541.  ISSN:  1080-6040
URL: http://www.ncbi.nlm.nih.gov/sites/entrez?linkbar=plain&db=journals&term=1080-6040
NAL Call Number:  RA648.5.E46
Descriptors:  cattle, bacterial disease, zoonotic aspects, bovine tuberculosis transfer to humans, disease transmission, UK.

Sreedevi, B.; Krishnappa, G.  Standardization of polymerase chain reaction for the detection of Mycobacterium tuberculosis complex organisms from bovines.  Indian Journal of Animal Sciences.  2004; 74 (11): 1120-1123.  ISSN:  0367-8318
NAL Call Number: 41.8 IN22
Descriptors:  cattle, Mycobacterium tuberculosis complex, Mycobacterium bovis, Mycobacterium avium, Mycobacterium phlei, polymerase chain reaction, PCR, laboratory techniques, genetic techniques, biopsy, diagnostic techniques, Bangalore, India.

Teklu, A.; Asseged, B.; Yimer, E.; Gebeyehu, M.; Woldesenbet, Z.  Tuberculous lesions not detected by routine abattoir inspection: the experience of the Hossana municipal abattoir, southern Ethiopia.  Revue Scientifique et Technique Office International des Epizooties.  2004; 23 (3): 957-964.  ISSN:  0253-1933.
Descriptors:  detection of tuberculous cattle, routine post slaughter inspection, tissues collection, testing for Mycobacterium bovis, 4.5% found to have tuberculous lesions, routine plant inspections found fewer, lungs and thoracic lymph nodes, obvious need for a higher level of accuracy at necropsy.

Thom, M.; Morgan, J.H.; Hope, J.C.; Villarreal-Ramos, B.; Martin, M.; Howard, C.J.  The effect of repeated tuberculin skin testing of cattle on immune responses and disease following experimental infection with Mycobacterium bovis.  Veterinary Immunology and Immunopathology.  2004; 102 (4): 399-412.  ISSN: 0165-2427
URL:http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number:  SF757.2.V38
Descriptors:  cattle, tuberculin testing, repeated skin testing, immune responses to testing, experimental infection with Mycobacterium bovis.

UK, Department for Environment Food and Rural Affairs.  Zoonoses Report United Kingdom 2003.  Published by the Department of Environment, Food and Rural Affrairs (DEFRA).  2004; 71  ISBN:  0855211407
URL:  www.defra.gov.uk
Descriptors:  humans cattle, livestock, avian influenza, bovine spongiform encephalopathy, Creutzfeldt Jakob disease, disease prevalence, disease surveys, disease transmission, epidemiology, foodborne diseases, vector borne diseases, waterborne diseases, West Nile fever, Borrelia, Campylobacter, Cryptosporidium, Escherichia coli, Hantavirus, Leptospira, Listeria, Mycobacterium bovis, Salmonella, Streptococcus, Toxocara, Toxoplasma, Trichinella, zoonoses, UK.

Vesosky, B.; Turner, O.C.; Turner, J.; Orme, I.M.  Gamma interferon production by bovine gammadelta T cells following stimulation with mycobacterial mycolylarabinogalactan peptidoglycan.  Infection and Immunity.  2004; 72 (8): 4612-4618.  ISSN:  0019-9567
URL: http://iai.asm.org
NAL Call Number: QR1.I57
Abstract:  A large percentage of lymphocytes in the blood of cattle express the gammadelta T-cell receptor, but specific functions for these cells have not yet been clearly defined.  There is evidence, however, that human, murine, and bovine gammadelta T-cells have a role in the immune response to mycobacteria.  This study investigated the ability of bovine gammadelta T-cells to expand and produce gamma interferon (IFN-gamma) in response to stimulation with mycobacterial products.  Bovine gammadelta T-cells, isolated from the peripheral blood of healthy cattle, expanded following in vitro stimulation with live mycobacteria, mycobacterial crude cell wall extract, and Mycobacterium bovis culture filtrate proteins.  In addition, purified gammadelta T-cells, co-cultured with purified monocytes and interleukin-2, consistently produced significant amounts of IFN-gamma in response to mycobacterial cell wall.  The IFN-gamma-inducing component of the cell wall was further identified as a proteolytically resistant, non-sodium dodecyl sulfate-soluble component of the mycolylarabinogalactan peptidoglycan.
Descriptors:  cattle, gamma interferon production, bovine gammadelta T cells, lymphocytes, ability to expand and produce IFN-gamma, stimulation, live mycobacteria, mycobacterial crude cell wall extract, Mycobacterium bovis culture filtrate, cell biochemistry.

Vordermeier, M.; Goodchild, A.; Clifton-Hadley, R.; Rua, R.de la.  The interferon-gamma field trial: background, principles and progress.  Veterinary Record.  2004; 155 (2): 37-38
Descriptors:  cattle, Mycobacterium bovis, tuberculin skin tests, interferon-gamma test, latent infections, diagnostic techniques, disease course, histopathology, cell mediated immune response, immunodiagnosis.

Waters, W.R.; Nonnecke, B.J.; Palmer, M.V.; Robbe-Austermann, S.; Bannantine, J.P.; Stabel, J.R.; Whipple, D.L.; Payeur, J.B..; Estes, D.M.; Pitzer, J.E.; Minion, F.C.  Use of recombinant ESAT-6:CFP-10 fusion protein for differentiation of infections of cattle by Mycobacterium bovis and by M. avium subsp. avium and M. avium subsp. paratuberculosis.  Clinical and Diagnostic Laboratory Immunology.  2004; 11 (4): 729-735.  ISSN:  1071-412X
Descriptors:  cattle, Mycobacterium bovis, Mycobacterium avium ssp paratuberculosis, diagnosis, comparison, vitro responses, recombinant ESAT-6:CFP-10 (rESAT-6:CFP-10) fusion protein by blood leukocytes, cattle naturally exposed to Mycobacterium avium or experimentally challenged with Mycobacterium avium ssp. avium, Mycobacterium avium ssp. paratuberculosis compared to responses by ycobacterium bovis-infected cattle.

Yang, WeiChong; Jiao, XinAn.  The advances in diagnosis techniques of bovine tuberculosis. Chinese Journal of Zoonoses.  2004; 20 (12): 1090-1093.  ISSN:  1002-2694.  Note:  In Chinese.  
Descriptors:  Mycobacterium bovis, cattle disease, bovine tuberculosis, diagnostic techniques, animal experiments, ELISA, blood, lymphocytes, chromatography, cytokines, genetics, hyperplasia, immunity, immunology, interleukin 2; lipids, PCR, RFLP, molecular biology, sampling, screening, serology, tuberculin, Western blotting, antibody competitive tests, dot immunogold filtration assay, fluorescent polarization assay, interferon gamma, sensitivity, sequencing, smear tests.

Yei, Ku Song; Wu, Yeong Huey; Liao, Ming Huei; Liu, Hung Jen; Chang, Ching Dong; Shiau, Chung Jung.  Difficulties in eradication of tuberculosis infected cows from the infected dairy herds in TaiwanTaiwan Veterinary Journal.  2004; 30 (1): 56-63.  ISSN:  1682-6485.  Note:  In Chinese.  
Descriptors:  cattle, Mycobacterium bovis, diagnostic testing, intradermal tuberculin test (ITT), gamma interferon test (IFN-gamma test), duplex polymerase chain reaction (duplex PCR), blood, nasal mucus samples, milk samples, difficulty eliminating disease, disease reservoirs on the farms, humans, dogs, cats, rats, nasal discharges and raw milk exposed calves, Taiwan.

 

2003

Adams, S.J.R. Badgers and bovine TB: bio-indicator or source? Veterinary Times. 2003, 33 (9) 8-10. ISSN: 1352-9374
Descriptors:  badgers, cattle, deer, Mycobacterium bovis, disease transmission patterns, disease vectors, sentinel animals, vector potential, tuberculosis, reviews. 

Ameni, G.; Amenu, K.; Tibbo, M. Bovine Tuberculosis:  Prevalence and risk factor assessment in cattle, and cattle owners in Wuchali-Jida District, Central Ethiopia.  Journal of Applied Research in Veterinary Medicine.  2003, 1 (1) 17-26.  ISSN: 1542-2666.
NAL Call Number:  SF601.J63
Descriptors:  Mycobacterium bovis, Mycobacterium tuberculosis, zoonotic disease potential, cattle, humans, risk factors, disease prevalence, risks of food consumption, poor sanitary measures, lack of understanding about zoonotic potential, Ethiopia.

Ameni, G.; Bonnet, P.; Tibbo, M.  A cross-sectional study of bovine tuberculosis in selected dairy farms in Ethiopia.  Journal of Applied Research in Veterinary Medicine.  2003; 1 (4): 253-258.  ISSN:  1542-2666
NAL Call Number:  SF601.J63
Descriptors:  1171 dairy cattle, 12 dairy farms, Holstein, Zebu crosses, 46.8% animal prevalence, 91.7 herd prevalence, Mycobacterium bovis, comparative intradermal tuberculin test, bacteriological study, milk cultures, 548 animals positive, positive correlation between herd size and prevalence of M. bovis, farm and breed differences, management effects, sanitary measures, economic effect of disease, public health risks, husbandry practices, Ethiopia.

Bonesi, G.L.; Scalone, B.C.V.; Okano, W.; Rosa, A.  Lesoes hepaticas em bovinos abatidos em matadourofrigorifico.  [Hepatic lesions in cattle slaughtered in a refrigerator abattoir.]  Higiene Alimentar. 2003, 17 (106) 78-83.  Note: In Portuguese with an English summary.
Descriptors: cattle, various diseases, post-slaughter examinations, lesions, 6.8% showed liver abscesses; slaughter, teleangiectasis, hepatic congestion, perihepatitis, cirrhosis, hepatitis, hydatidosis, fasciolosis, tuberculosis, Parna, Brazil.

Buddle, B.M.; Wedlock, D.N.; Parlane, N.A.; Corner, L.A.L.; De Lisle, G.W.; Skinner, M.A.   Revaccination of neonatal calves with Mycobacterium bovis BCG reduces the level of protection against bovine tuberculosis induced by a single vaccination.  Infection and Immunity.  2003; 71 (11): 6411-6419.  ISSN:  0019-9567
URL: http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  Cattle may provide a suitable model for testing ways of improving tuberculosis vaccine efficacy in human infants.  A vaccination and challenge study was undertaken in calves to determine the optimal time to vaccinate neonatal animals with Mycobacterium bovis bacillus Calmette-Guerin (BCG) for protection against tuberculosis and to determine whether revaccination with BCG was beneficial.  Calves (10 per group) were vaccinated with BCG within 8 h of birth or at 6 weeks of age, when immune responses to antigens of environmental mycobacteria were detectable, or vaccinated at birth and revaccinated at 6 weeks.  A control group was not vaccinated. BCG vaccination at birth induced strong antigen-specific gamma interferon (IFN-gamma) and interleukin-2 (IL-2) responses and antigen-specific activation in CD4+, CD8+, and WC1+ gammadelta T-cell subsets from blood. The proportions of animals per group with macroscopic tuberculous lesions after challenge were 0/10 for BCG at birth, 1/9 for BCG at 6 weeks, 4/10 for the revaccinated group, and 10/10 for the nonvaccinated group.  There was no significant difference in the levels of protection between groups vaccinated at birth or at 6 weeks, while animals vaccinated both at birth and at 6 weeks had significantly less protection than those vaccinated only at birth.  The revaccinated calves that subsequently developed tuberculous lesions had significantly stronger IFN-gamma and IL-2 responses to bovine purified protein derivative after the BCG booster than those in the same group that did not develop lesions.  The results indicated that BCG vaccination at birth induced a high level of immunity and that the sensitization of very young animals to antigens of environmental mycobacteria by 6 weeks of age did not affect the effectiveness of BCG.  However, BCG revaccination of these young animals was contraindicated.
Descriptors:  vaccination, clinical techniques, Friesian calves, Mycobacterium bovis, strain Pasteur 1173P2, strain Wag202, BCG vaccine, immune system, IFN-gamma/delta subsets, CD4+, CD8+, WC1+.

Buddle, B.M.; Pollock, J.M.; Skinner, M.A.; Wedlock, D.N.  Development of vaccines to control bovine tuberculosis in cattle and relationship to vaccine development for other intracellular pathogens.  International Journal for Parasitology.  2003; 33 (5-6): 555-566.  ISSN: 0020-7519.  Note:  In the special issue: Vaccines in the 21st century: Expanding the Boundaries of Human and Veterinary Medicine.  Edited by D. Brake.
NAL Call Number:  QH547.I55  
Abstract:  Vaccination of cattle against bovine tuberculosis could be an important strategy for the control of disease either where there is a wildlife reservoir of Mycobacterium bovis infection or in developing countries where it is not economically feasible to implement a 'test and slaughter' control program.  Advances in the understanding of protective immune responses to M. bovis infection in cattle and the advent of new molecular biological techniques, coupled with the sequencing of the M. bovis genome have provided opportunities for the rational development of improved tuberculosis vaccines.  A number of new tuberculosis vaccines including attenuated M. bovis strains, killed mycobacteria, protein and DNA vaccines are under development and many are being assessed in cattle.  Recent results have revealed several promising vaccine candidates and vaccination strategies.  Ways of distinguishing between vaccinated and infected cattle are becoming available and the possibility of new approaches to the eradication of tuberculosis from domestic livestock is discussed.  Similarities between the mechanisms of protective immunity against M. bovis and against other intracellular parasites continue to be found and discoveries from vaccine studies on bovine tuberculosis may provide helpful insights into requirements for vaccines against other intracellular pathogens.
Descriptors:  Mycobacterium bovis, bovine tuberculosis, vaccine development, vaccines, immunity, vaccination cattle, BCG vaccine, literature reviews.

Cavirani, S.; Fanti, F.; Benecchi, M.; Calderaro, A.; Taddei, S.; Arcangeletti, C.; Medici, M.C.; Dettori, G.; Chezzi, C.  Evaluation of susceptibility of Mycobacterium bovis to antituberculous drugs by radiometric BACTEC 460TB system.  Microbiologica.  2003; 26 (2): 181-186.  ISSN:  1121-7138
Descriptors:  cattle, Mycobacterium bovis, strain susceptibility to antibiotics, post slaughter cattle, tissue sampling of lesions, 61 strains collected, 41 susceptible to isoniazid and rifampin, 13 resistant to isoniazid only, not strains resistant to rifampin only, 2 strains reistant to both drugs, Italy

Corner, L.A.L.; Stevenson, M.A.; Collins, D.M.; Morris, R.S. The re-emergence of Mycobacterium bovis infection in brushtail possums (Trichosurus. vulpecula) after localised possum eradication. New Zealand Veterinary Journal. 2003, 51 (2) 73-80.
NAL Call Number: 41.8 N483
Descriptors:  cattle, brushtail possums, Mycobacterium bovis, infection patterns, wild animal disease vectors and reservoirs, epidemiology, pest control, spatial distribution patterns, tuberculosis, vector potential,
New Zealand.

De Sousa, R.D.; Reis, D.O.; Guimaraes, K.C.S.; Aquino, C.A.M.  Linfonodos com maior frequencia de localizacao para tuberculose bovina, em animais abatidos em um frigorifico sob inspecao federal, no municipio de Uberlandia-MG.  [Lymph nodes with the greatest frequency of localization of bovine tuberculosis, in slaughtered animals kept in a refrigerator under federal inspection, in the municipality of Uberlandia-MG.] Higiene Alimentar. 2003, 17 (106) 35-39. ISSN: 0101-9171  Note: In  Portuguese with an English summary.
Descriptors:  cattle, Mycobacterium bovis, cattle bacterial diseases, post-slaughter examination, disease incidence, tuberculosis, lesions, lymph nodes, slaughter, Minas Gerais, Brazil.

Diaz-Otero, F.; Banda-Ruiz, V.; Jaramillo-Meza, L.; Arriaga-Diaz, C.; Gonzalez-Salazar, D.; Estrada-Chavez, C. Identification of Mycobacterium bovis infected cattle by immunological and molecular methods.  Veterinaria Mexico. 2003, 34 (1) 13-26.  ISSN:  0301-5092  Note: In Engish and Spanish.
NAL Call Number: SF604.V48
Descriptors:  dairy cattle, Mycobacterium bovis, antibodies, ELISA, immunodiagnosis, immunological techniques, interferon, spoligotyping, serological surveys, control, anergic animals,
Mexico

Fletcher, J. Tuberculosis again? Deer Farming. 2003, No.72, 20-24.
Descriptors: deer, bovine tuberculosis, Mycobacterium, delayed type hypersensitivity, epidemiology, skin tests, zoonoses

Gallaher, E.; Kelly, L.; Pfeiffer, D.U.; Wooldridge, M.  A quantitative risk assessment for badger to cattle transmission of Mycobacterium bovis Proceedings of a meeting Society for Veterinary-Epidemiology and Preventive Medicine. [Great Britain].  2003: 33-44.  ISSN: 0956-7496.  Note:  Meeting held March 31-April 2, 2003, Warwick, England.
NAL Call Number:  SF780.9.S63
Descriptors:  cattle, badgers, Mycobacterium bovis, bovine tuberculosis, disease transmission, risk assessment, mathematical models.

Garnett, B.T.; Roper, T.J.; Delahay, R.J. Use of cattle troughs by badgers (Meles meles).  A potential route for the transmission of bovine tuberculosis (Mycobacterium bovis) to cattle.  Applied Animal Behavior Science.  2003. 80 (1): 1-8.  ISSN: 0168-1591
URL:  http://www.elsevier.com/wps/find/journaldescription.cws_home/503301/description#description
NAL Call Number:  QL750.A6
Descriptors:  badgers Meles meles, wild animals, cattle diseases, Mycobacterium bovis, cattle feed troughs height, wild animals, cattle-diseases, bovine  tuberculosis, disease transmission, feces, vertebrate pests, wildlife/livestock interactions, wildlife food habits, United Kingdom.

Goodchild, A.V.; De La Rua Domenech, R.; Palmer, S.; Dale, J.; Gordon, S.V.; Hewinson, R.G.; Clifton-Hadley, R.S.  Association between molecular type and the epidemiological features of Mycobacterium bovis in cattle.  Proceedings of a meeting Society for Veterinary Epidemiology and Preventive Medicine. [Great Britain]  2003: 45-59.  ISSN: 0956-7496.  Note:  Meeting was held March 31-April 2, 2003, Warwick, England.
NAL Call Number:  SF780.9.S63
Descriptors:  cattle, Mycobacterium bovis, epidemiology, polymerase chain reaction, PCR, spoligotyping, variable number tandem repeats, spatial analysis.

Gormley, E.; Costello, E. Tuberculosis and badgers: new approaches to diagnosis and control.  Society for Applied Microbiology Symposium Series. 2003, No.32, 80S-86S.   
NAL Call Number: QR1.S64 no. 32

Descriptors: Eurasian badger, Meles meles, wild animal disease reservoir, cattle, Mycobacterium bovis infection, disease control eradication programs, diagnosis of disease in badgers, profiles of disease episodes, possible vaccination, Ireland, Great Britain.

Howard, C.J.; Charleston, B.; Stephens, S.A.; Sopp, P.; Hope, J.C.  The role of dendritic cells in shaping the immune response.  Animal Health Research Reviews.  2004; 5 (2): 191-195.  Note:  Proceedings of the 3rd International Veterinary Vaccines and Diagnostics Conference, University of Guelph, Canada, 13-18 July 2003.
Descriptors:  cattle, livestock, dendritic cells, immune responses, stimulating naïve T cells, adaptive immunity, in vivo, ex-vivo, subpopulations of myeloid dendritic cells, cytokines, vaccination, Mycobacterium bovis.

Jian, MinHua; Xu, ZhaoHua; Shao, WeiJie (et-al).  Enzyme-linked immunosorbent assay for detection of bovine IgG antibody to Mycobacterium tuberculosis. Chinese Journal of Zoonoses. 2003, 19 (2) 81-82.  Note:  In Chinese with an English summary.  
Descriptors:  cattle, Mycobacterium tuberculosis, antibodies, detection assay method, blood serum, ELISA, IgG, lipopolysaccharides, monoclonal antibodies, auxiliary test for intradermal test.

Koets, Ad.P.  Mycobacterial heat shock proteins and the bovine immune system. In W. van Eden,  Birkhaeuser Verlag, Basel.  Heat shock proteins and inflammation.  2003: 233-244.  ISBN:  3764369329.  
Descriptors:  bovines, Mycobacterium avium ssp. paratuberculosis, Mycobacterium bovis, heat shock proteins, immunodominant antigens, bacterial disease, gamma delta T-cell, blood and lymphatics, immune system, physiology.

Komaromy, A.M.; Andrew, S.E.; Brooks, D.E.; Detrisac, C.J.; Gelatt, K.N.  Periocular sarcoid in a horse.  Veterinary Ophthalmology.  2004; 7 (3): 141-146.  ISSN: 1463-5216
NAL Call Number:  SF891.V47
Descriptors:  Thoroughbred mare, horse, case report, eyelid sarcoid, neoplasms, Mycobacterium bovis BCG.

Malone, F.E.; Wilson, E.C.; Pollock, J.M.; Skuce, R.A.  Investigations into an outbreak of tuberculosis in a flock of sheep in contact with tuberculous cattle. Journal of Veterinary Medicine Series B.  2003; 50 (10): 500-504.  ISSN:  0931-1793
Descriptors:  sheep, cattle, Mycobacterium bovis, first evidence of transmission from cattle to sheep, animals with positive comparative intradermal tuberculin test, postmortem examination, tuberculous lesions, strain typing spoligotyping and variable tandem repeats typing, in vitro release of interferon-gamma, histopathology, Britain, Ireland, UK.

Martinez-Vivot, M.; Zumarraga, M.; Romano, M.; Cataldi, A.; Diz, L.; Guida, N.; Barboni, A.; Moras, E.V.  Aplicacion del spoligotyping para identificar el origen de reinfeccion de tuberculosis bovina en un tambo de la provincia de Buenos Aires. [Usefulness of spoligotyping to identify the origin of reinfection of bovine tuberculosis in a dairy farm in the province of Buenos Aires.]  Veterinaria Argentina. 2003, 20 (191) 27-31.   Note:  In Spanish with an English summary.   
NAL Call Number: SF604.V463
Descriptors:  dairy cattle, PPD intradermal test, Mycobacterium bovis, infection source, spoligotyping test, disease survey, re-infection, tuberculous lesions,
Argentina

Maue, Alex C.; Waters, W. Ray; Palmer, Mitch; Estes, D.Mark.  Costimulatory molecules augment DNA vaccine-induced immunity to experimental bovine tuberculosis.  FASEB Journal.  2003; 17 (7): C26.  ISSN:  0892-6638. Note:  Meeting abstract.  90th Anniversary Annual Meeting of the American Association of Immunologists, Denver, CO, USA; May 06-10, 2003.
Descriptors:  bovine tuberculosis, DNA vaccines, immunostimulant drug, mouse model, Mycobacterium bovis, co-stimulatory molecules, laboratory techniques, immune responses.

Milian-Suazo, F.; Anaya-Escalera, A.M.; Gallegos-Torres, R.M.  A review of M. bovis BCG protection against TB in cattle and other animals species.  Preventive Veterinary Medicine. 2003, 58 (1-2) 1-13.    
NAL Call Number: SF601.P7 
Descriptors: cattle, Mycobacterium bovis BCG strain, disease control, immunity, potency, reviews, tuberculosis vaccination, vaccine development.

Mota, P.M.P.C.; Motta, P.M.C.; Lobato, F.C.F.; Lage, A.P.; Ribeiro, A.C.C.L.; Leite, R.C.  Avalaicao do tratamento com isoniazida em bovinos infectados naturalmente pelo Mycobacterium bovis.  [Evaluation of the treatment with isoniazid carried out in bovines naturally infected with Mycobacterium bovis.] Arquivo Brasileiro de Medicina Veterinaria e Zootecnia.  2004; 56 (5): 581-588.  ISSN:  0102-0935.  Note:  In Portuguese.
Descriptors:  cattle, 240 animals, naturally infected herd, intermittent treatment with isoniazid, oral dosing of 3x/week, for 10 months, efficacy of the drug, treatment did not cause selection of drug resistant strains.

New Zealand, Livestock Improvement Corporation Limited. Dairy Statistics Livestock Improvement Corporation Limited, 2001-2002. 2003, 45 pp.  Note:  Published by the Livestock Improvement Corporation Ltd, New Zealand Dairy Board; Hamilton; New Zealand
Descriptors: national dairy cattle, statistics, disease control, animal breeding, bovine leucosis and tuberculosis, Mycobacterium, calving, dairy industry, disease control, herd improvement, milk production, statistics, trends, New Zealand.  

Nonnecke, B. J.; Waters, W.R.; Foote: M.R.; Fowler, R.M.; Horst, R.L.; Miller, B.L. Interferon-C and TNF-C secretion by mononuclear leukocytes from peripheral blood of young and adult cattle, vaccinated with Mycobacterium bovis BCG: Modulation by 1,25-dihydroxyvitamin D3.  International Journal of Vitamin and Nutrition Research.  2003 73: 235-244.
Descriptors:  cattle, age goup comparison,  immunological response, white blood cells,  peripheral blood sampling, vaccination, Mycobacterium bovis BCG, effects of 1,25-dihydroxyvitamin D3 .

Popluhar, L.; Hyzova, A.  Tuberkuloza zvierat ako zoonoza aj ako antropozoonoza.  [Tuberculosis of animals as zoonosis as well as anthropozoonosis.]  Slovensky Veterinarsky Casopis.  2003; 28 (6): 38-39.  ISSN:  1335-0099.  Note:  In Slovakian with an English summary.  
Descriptors:  elimination of animal tuberculosis, Mycobacterium bovis; Mycobacterium bovis BCG strain, BCG vaccine, vaccination, diagnosis, disease prevention and control, disease prevalence, zoonoses, Czechoslovakia

Rajeev Singh; Hari Shankar.  Occurrence of tuberculosis at an organized cattle farm.  Indian Veterinary Journal.  2003; 80 (11): 1100-1102.  ISSN:  0019-6479
NAL Call Number:  41.8 IN2
Descriptors:  4696 cattle, Mycobacterium bovis, tuberculin testing for 3 years, 107 developed the disease, mortality rated recorded, age differences, disease prevalence, epidemiology, Uttar Pradesh, India.

Ramirez, I.C.; Santillan, M.A.; Dante,V. The goat as an experimental ruminant model for tuberculosis infection.  Small Ruminant Research. 2003, 47 (2) 113-116.  ISSN: 0921-4488    
NAL Call Number: SF380.I52
Abstract:  Young goats were inoculated intratracheally with a low dose of Mycobacterium bovis to determine if they develop lesions similar to those seen in the natural disease in cattle.  After 3 months, the challenge induced small lesions (< 1 cm diameter) localized in the lungs and pulmonary lymph nodes, similar to those seen in the natural cattle disease.  All of the M. bovis-inoculated young goats showed strong cellular immune responses to bovine PPD.  Results of the present study suggest that young goats can be used as animal models since a low dose challenge mimics the natural pathogenesis and pathology processes caused by M. bovis in cattle.
Descriptors:  goats, animal model for disease, experimental infection, immune response, kids, lesions, Mycobacterium bovis, tuberculosis. 

Reid, S.W.J. (ed); Menzies, F.D.  Society for Veterinary Epidemiology and Preventive Medicine. Proceedings of a meeting held at University of Warwick, England, 31st-March 2nd April 2003. 2003, 277 pp.  Note:  The proceedings has 21 articles on a variety of topics related to animal diseases. 
Descriptors: cattle, dogs, horses, Mycobacterium bovis, epidemiology of bovine tuberculosis, injuries, FMD, heart diseases, mastitis, satellite imagery, vaccination.

Roper, T.J.; Garnett, B.T.; Delahay, R.J. Visits to farm buildings and cattle troughs by badgers (Meles meles): a potential route for transmission of bovine tuberculosis (Mycobacterium bovis) between badgers and cattle. Cattle Practice. 2003, 11 (1) 9-12. ISSN:  0969-1251    
NAL Call Number: SF961.C37

Descriptors:  cattle, farms, tracking wild badgers, Meles meles, nighttime visits to farms, climate, Mycobacterium bovis, cats, foxes,disease transmission, feces, feed trough contamination, rain, urine, diasese control.  

Shirima, G.M.; Kazwala, R.R.; Kambarage, D.M. Prevalence of bovine tuberculosis in cattle in different farming systems in the eastern zone of Tanzania.  Preventive Veterinary Medicine. 2003, 57 (3) 167-172. ISSN: 0167-5877
NAL Call Number: SF601.P7
Descriptors:  Mycobacterium bovis, Zebu cattle, free-ranging system, internsive management, intradermal tuberculin testing, incidence levels in two systems, disease survey, epidemiology,
Tanzania

Sreedevi, B.; Krishnappa, G.  Pathogenesis of Mycobacterium tuberculosis isolated from cattle.  Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases.  2003; 24 (1): 59-62.  ISSN:  0970-9320
Descriptors:  cattle, Mycobacterium, Mycobacterium avium, Mycobacterium bovis, Mycobacterium tuberculosis in cattle, different mycobacterial cultures, bovine macrophage cell cultures, NBT dye reduction test, disease transmission, levels of pathogenisity, phagocytosis, cattle as host organisms.

Sreedevi, B.; Krishnappa, G.  Detection of Mycobacterium tuberculosis complex organisms in clinical samples of cattle by PCR and DNA probe methods.  Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases.  2003; 24 (2): 167-171.  ISSN:  0970-9320
Descriptors:  cattle, Mycobacteriumj bovis, Mycobacterium phlei, Mycobacterium tuberculosis, Mycobacterium bovis, BCG, Mycobacterium avium, Mycobacterium avium ssp. paratuberculosis, Mycobacterium tuberculosis complex, diagnosis, diagnostic techniques, DNA probes, polymerase chain reaction, PCR,primers for IS6110, dot blot hybridization, tuberculin, tuberculosis, blood samples, milk samples, semen samples, Karnataka, India.

Usabiaga, J.  Intersectoral Coordination-between-Health and Agriculture:-Zoonoses, Food Safety and Foot and Mouth Disease Final Report and Proceedings, XII-Inter American Meeting, Sao Paulo, Brazil, 2-4 May 2001.  2003: 119-132.  ISBN:  9275124507.  Note:  Published by the Pan American Health Organization, Pan American Sanitary Bureau, Washington, DC, US.
Descriptors:  cattle, goats, humans, Mycobacterium bovis, Brucella, tuberculosis, animal health, brucellosis, disease prevention and control programs, disease prevalence, disease surveys, disease transmission, zoonotic diseases, epidemiology, public health, food contamination, food safety, international trade, participation, public health, quality controls, Latin America.

Vordermeier, H.M.; Lowrie, D.B.; Hewinson, R.G.  Improved immunogenicity of DNA vaccination with mycobacterial HSP65 against bovine tuberculosis by protein boosting. Veterinary Microbiology. 2003, 93 (4) 349-359.  ISSN:  0378-1135
NAL Call Number: SF601.V44
Descriptors: cattle, adjuvants, bacterial antigens, cell mediated immunity, disease control and prevention, Mycobacterium tuberculosis, DNA, humoral immunity, IgG, immune response, immunization, immunogenetics, interferon, lymphocyte transformation, recombinant proteins, tuberculin, tuberculosis, vaccination, vaccines.

Waters, W.R.; Nonnecke, B.J.; Foote, M.R.; Maue, A.C.; Rahner, T.E.; Palmre, M.V. Whipple, D.L.: Horst, R.L.; Estes, D.M. Mycobacterium bovis bacilli Calmette Guerin vaccination of cattle, activation of bovine CD4+ and  CC-TCR+ cells and modulation by 1,25-dihydroxyvitamin D3  Tuberculosis, 2003, 83: 287-297.
Descriptors:  cattle, Mycobacterium bovis BCG, vaccination, immune response, CD4+ and  CC-TCR+ cells,  effects of dihydroxyvitamin D3

Waters, W.R.; Palmer, M.V.; Whipple, D.L; Carlson, M.C.; Nonnecke, B.J.  Diagnostic implication of antigen-induced IFN-C, nitric oxide, and TNF-C production by blood mononuclear cells from Mycobacterium bovis-infected cattle.  Clinical and Diagnostic Laboratory Immunology.  2003, 10: 960-966.
Descriptors: cattle, Mycobacterium bovis, disease effects,  immunological response, mononuclear blood cells, white cells, antigen induced responses, possible diagnostic value.

Wedlock, D.N.; Skinner, M.A.; Parlane, N.A.; Vordermeier, H.M.; Hewinson, R.G.; De Lisle, G.W.; Buddle, B.M.  Vaccination with DNA vaccines encoding MPB70 or MPB83 or a MPB70 DNA prime-protein boost does not protect cattle against bovine tuberculosis.  Tuberculosis (Amsterdam). 2003; 83 (6): 339-349.  ISSN:  1472-9792
URL:  http://www.elsevier.com/wps/find/journaldescription.cws_home/638428/description?navopenmenu=-2
Descriptors:  cattle, Mycobacterium bovis, bovine tuberculosis, DNA vaccines, control strategy, antigens, vaccinated with MPB83 DNA, MPB70 DNA, or DNA followed by MPB70 protein or injected with BCG or control plasmid DNA, did not induce immunity in calves.

Whelan, A.O.; Hope, J.C.; Howard, C.J.; Clifford, D.; Hewinson, R.G.; Vordermeier, H.M.  Modulation of the bovine delayed-type hypersensitivity responses to defined mycobacterial antigens by a synthetic bacterial lipopeptide.  Infection and Immunity.  2003; 71 (11): 6420-6425.  ISSN:  0019-9567
URL: http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  The use of defined protein and peptide antigens can overcome specificity limitations of purified protein derivatives in the detection of bovine tuberculosis when the antigens are used in blood-based tests.  Since the use of these specific antigens as skin test reagents could have practical advantages, we investigated the potential of Mycobacterium bovis-specific antigens to stimulate delayed-type hypersensitivity (DTH) responses in cattle experimentally infected with M. bovis.  A cocktail of the recombinant antigens ESAT-6, MPB83, and MPB64 failed to stimulate in vivo DTH in cattle that had been experimentally infected with M. bovis despite the fact that the antigens were recognized in vitro by the same animals.  However, it was possible to stimulate antigen-specific bovine DTH responses by using ESAT-6 in combination with a synthetic bacterial lipopeptide.  This lipopeptide stimulated the release of the proinflammatory cytokine tumor necrosis factor alpha from monocyte-derived bovine dendritic cells in vitro, thereby providing a possible mechanism for its DTH-enhancing properties.
Descriptors:  Mycobacterium bovis, detection methods, defined protein and peptide antigens, skin reagents, stimulation of delayed-type hypersensitivity, cattle synthetic bacterial lipopeptide.

Wilson, RT. Animal health and disease control in the Usangu Wetland of Southwestern Tanzania. Tropical Animal Health and Production. 2003, 35 (1) 47-67.  ISSN: 0049-4747  Note:  In English with French and English summaries.    
NAL Call Number: SF601.T7
Descriptors: livestock, African swine fever, animal diseases, animal health, anthrax, cysticercosis, disease control, environmental factors, epidemiology, foot and mouth disease, pleuropneumonia, rabies,  Rift Valley fever, rinderpest, trypanosomiasis, tuberculosis, veterinary services, African swine fever virus, Glossina, lumpy skin disease virus, Theileria parva, Tanzania.

Zhang, XiYue; Wang, JunWei; Gao, YunHang; He, ZhaoYang.  Comparison of three methods on detecting bovine tuberculosis in cattle ranch.  Chinese Journal of Veterinary Science.  2003; 23 (6): 555-556.  ISSN:  1005-4545.  Note:  In Chinese with an English summary.  
Descriptors:  498 cattle, infected with Mycobacterium bovis, diagnostic techniques, diagnosis, bovine tuberculosis allergic reaction, Dot-IGSS, ELISA, recommend both tests, China.

2002

Abou Eisha, A.M.; El Attar, A.A.; El Sheary, M.N. Bovine and atypical mycobacterial infections of cattle and buffaloes in Port Said Province, Egypt. Assiut Veterinary Medical Journal. 2002. 47 (93) 152-162.
NAL Call Number:  SF604 A77
Descriptors:  Bubalus, disease incidence, epidemiology, lymph nodes, tuberculin, tuberculosis, buffalo, cattle, Mycobacterium avium complex, Mycobacterium bovis, Mycobacterium fortuitum, Mycobacterium kansasii, Mycobacterium smegmatis, Egypt.

Adhikary, M.K.; Mondal, M.; Basak, D.K.  Pulmonary tuberculosis in cattle -- a study on its incidence and pathology.  Journal of Interacademicia. 2002, 6 (Special issue) 694-699.
Descriptors:   adult cattle, post-slaughter tissue sampling, lungs, lesions described, disease incidence levels, histopathological examinations, tubercles, epidemiology,
India

Amadori, M.; Lyashchenko, K.P.; Gennaro, M.L.; Pollock, J.M.; Zerbini, I. Use of recombinant proteins in antibody tests for bovine tuberculosis. Veterinary Microbiology. Apr 2, 2002. 85 (4) 379-389. ISSN: 0378-1135
NAL Call Number:  SF601.V44
Abstract:  Tuberculosis (TB) in cattle remains a major zoonotic and economic problem in many countries. Since the standard diagnostic assay, the intradermal test (IDT) with bovine PPD tuberculin, has less than optimal accuracy in all situations, other diagnostic methods such as serological assays have been investigated. Because of fundamental concerns for the low sensitivity and specificity of previous ELISA protocols, a profiling ELISA with nine purified, recombinant proteins of TB complex mycobacteria, was employed on samples from four groups of cattle:  (a) naturally Mycobacterium avium-exposed and experimentally Mycobacterium bovis-infected, (b) officially-certified TB-free herds, (c) exposed to M. bovis in two field TB outbreaks and scored as bovine reactors in the gamma-IFN assay for bovine TB, (d) paratuberculosis (para TB)-infected. The described ELISA proved to be highly specific. In fact, the antibody (Ab) response could be consistently detected in 3 out of 3 endotracheally-infected calves and in 1 out of 3 contact-infected calves. There was also a very low prevalence of low-titered, non-specific Ab responses in paraTB-infected animals. As for the animals exposed to field TB outbreaks, 16 out of 28 gamma-IFN positive cattle were also Ab-positive; importantly, 7 out of 12 gamma-IFN positive, IDT negative cattle showed Ab responses to TB proteins. In general, the profile of the Ab response varied among animals; the reaction to single recombinant antigens was sometimes transient and fluctuating, whereas the panel of antigens on the whole was indeed more effective in Ab detection.
Descriptors:  cattle tuberculosis antibodies, diagnostic techniques, recombinant proteins, tuberculin, serology, ELISA, Mycobacterium avium, Mycobacterium bovis, outbreaks, interferon, Mycobacterium paratuberculosis, detection.

Amadori, M.; Tagliabue, S.; Lauzi, S.; Finazzi, G.; Lombardi, G.; Telo, P.; Pacciarini, L.; Bonizzi, L. Diagnosis of Mycobacterium bovis infection in calves sensitized by mycobacteria of the avium/intracellulare group.  Journal of Veterinary Medicine. Series B. 2002. 49 (2) 89-96.
NAL Call Number:  41.8 Z52
Descriptors:
  diagnosis, experimental infections, interferon, tuberculin, cattle, calves, Mycobacterium avium complex, Mycobacterium bovis, diagnostic procedures.

Anonomyous. A crisis in the making.  Veterinary Record. July 13, 2002. 151 (2) 33. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, tuberculosis, disease control, testing, UK.

Anonomyous.  Keeping the lid on bovine TB. Veterinary Record. Mar 2, 2002. 150 (9) 257. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle tuberculosis, Mycobacterium bovis, diagnosis, disease control.

Bengis, R.G.; Kock, R.A.; Fischer, J.  Infectious animal diseases: the wildlife/livestock interface. Revue Scientifique et Technique Office International des Epizooties. 2002. 21 (1) 53-65. Note:  In English with Spanish and French summaries.
NAL Call Number:  SF781 R4
Descriptors:  analytical methods, animal diseases, brucellosis, Brucella, diagnosis, diagnostic techniques, disease control, ecotourism, livestock, rinderpest, tuberculosis, wildlife conservation.

Buddle, B.M.; Wards, B.J.; Aldwell, F.E.; Collins, D.M.; de Lisle, G.W. Influence of sensitization to environmental mycobacteria on subsequent vaccination against bovine tuberculosis. Vaccine. 2002. 20 (7-8) 1126-1133.
NAL Call Number:  QR189 V32
Descriptors:  BCG vaccine, calves, cattle, humans, immune response, immunization, interferon, interleukin-2, live vaccines, potency, efficacy, tuberculosis, vaccination, virulence, Mycobacterium bovis, Mycobacterium avium, purified protein derivative, sensitization.

Buddle, B.M.; Skinner, M.A.; Wedlock, D.N.; Collins, D.M.; de Lisle, G.W.; Fossum, C. (ed.); Wattrang, E. New generation vaccines and delivery systems for control of bovine tuberculosis in cattle and wildlife. Veterinary Immunology and Immunopathology. 2002. 87 (3-4) 177-185. ISSN: 0165-2427.  Note: 6th International Veterinary Immunology Symposium, Ultuna Campus, Swedish University of Agricultural Sciences, Uppsala, Sweden, July 2001.
NAL Call Number:  SF757.2.V38
Descriptors:  vaccines, Mycobacterium bovis, cattle, wildlife.

Cataldi, A.A.; Gioffre, A.; Santtangelo, M.P.; Alito, A.; Caimi, K.; Bigi, F.; Romano, M.I.; Zumarraga, M. El genotipo de Mycobacterium bovis mayoritario en la Argentina lo es tambien en las Islas Britanicas: la tuberculosis bovina provino de Gran Bretana? [The prevailing genotype of Mycobacterium bovis in Argentina is also that of the British Isles: Did bovine tuberculosis originate in United Kingdom?] Revista Argentina de Microbiologia. 2002. 34 (1) 1-6. Note:  In Spanish with an English summary.
Descriptors:  cattle, Mycobacterium bovis, epidemiology, genotypes, imported infections, Argentina, Great Britain, USA.

Choi, K.P.; Kendrick, N.; Daniels, L.  Demonstration that fbiC is required by Mycobacterium bovis BCG for coenzyme F420 and FO biosynthesis.  Journal of Bacteriology. 2002, 184 (9) 2420-2428.  ISSN: 0021-9193    
NAL Call Number: 448.3 J82
Descriptors:  amino acid sequences, coenzyme F420 and FO biosynthesis, coenzymes, genes, histidine, mutants, proteins, Mycobacterium bovis BCG, antituberculosis drug PA-824. 

Cobner, A.J. Electronic submission of tuberculosis test data. Cattle Practice. 2002. 10 (4) 231-233.
NAL Call Number:  SF961 C37
Descriptors:  accuracy, data analysis, data collection and processing, recording, tests, tuberculosis, cattle, Mycobacterium bovis.

Cockle, P.J.; Gordon, S.V.; Lalvani, A.; Buddle, B.M.; Hewinson, R.G.; Vordermeier, H.M. Identification of novel Mycobacterium tuberculosis antigens with potential as diagnostic reagents or subunit vaccine candidates by comparative genomics. Infection and Immunity. 2002, 70 (12) 6996-7003. ISSN:  0019-9567    
NAL Call Number: QR1.I57
Descriptors: cattle, Mycobacterium bovis, Mycobacterium tuberculosis, bacterial antigens, diagnostic antigens, genes, immunization, molecular genetics, tuberculin, vaccination, vaccine development, vaccines.

Collins, J.D. The control of tuberculosis in cattle: an Irish view.  Cattle Practice. 2002. 10 (4) 223-229. 
NAL Call Number:  SF961 C37
Descriptors:  assays, detection, diagnosis, disease control, geographical information systems, risk, tests, tuberculin, tuberculosis, cattle, Mycobacterium bovis, Irish Republic.

Constant, P.; Perez, E.; Malaga, W.; Laneelle, M.A.; Saurel, O.; Daffe, M.; Guilhot, C. Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex: evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frameshift mutation in the pks15/1 gene. Journal of Biological Chemistry. 2002. 277 (41) 38148-38158.
NAL Call Number:  381 J824
Descriptors:  biosynthesis, genes, glycolipids, phenolic acids, tuberculosis, virulence, phthiocerol, Mycobacterium tuberculosis, phenolphthiocerol.

Cooksey, R.C.; Morlock, G.P.; Holloway, B.P.; Limor, J.; Hepburn, M. Temperature-mediated heteroduplex analysis performed by using denaturing high-performance liquid chromatography to identify sequence polymorphisms in Mycobacterium tuberculosis complex organisms.  Journal of Clinical Microbiology. 2002. 40 (5) 1610-1616.
NAL Call Number:  QR46.J6
Descriptors:  antituberculous agents, drug resistance, ethambutol, genes, genetic polymorphism, HPLC, isoniazid, methodology, mutations, nucleotide sequences, pyrazinamide, rifampicin, streptomycin, Mycobacterium tuberculosis.

Costantini, F. Aspetti igienico-sanitari degli allevamenti di ungulati selvatici: malattie infettive e monitoraggio sanitario. [Hygiene and health aspects affecting the breeding of wild ungulates. Infectious diseases and the monitoring of health.]  Notiziario ERSA. 2002, 15 (4) 21-25.  Note:  In Italian.
Descriptors: captive wild ungulates, health monitoring, African swine fever virusAphthovirus, Bluetongue virus, anthrax, brucellosis, enteritis, legislation, pleuropneumonia, Mycobacterium, tuberculosis, wild animals, Italy.

Cvetnic, Z.; Zeman, M.; Spicic, S.; Majnaric, D.; Bukovic-Sosic, B.; Mitak, M.  Epizootija tuberkuloze goveda u seoskom gospodarstvu. [Epidemiology of tuberculosis in cattle in a rural husbandry.] Veterinarska Stanica. 2002. 33 (1) 23-30. Note:  In Croatian with an English summary.
Descriptors:  cattle, clinical aspects, cows, disease prevalence, epidemiology, tuberculin, tuberculosis, Mycobacterium bovis, pigs, post-slaughter, Croatia.

Dandapat, P.; Rishendra,Verma; Venkatesan, K.; Sharma, V.D.; Katoch, V.M.; Verma, R.     Identification of the bound and unbound lipids on the cell envelopes of Mycobacterium bovis.  Indian Journal of Animal Sciences. 2002, 72 (11) 946-950.  ISSN:  0367-8318    
NAL Call Number: 41.8 IN22

Descriptors: 16 isolates, bovine tissue derivation, Mycobacterium tuberculosis, Mycobacterium bovis BCG, Mycobacterium avium, C-mycosides, phosphytidyl inositol mannosides, polar glycolipids, bacterial antigens, envelope glycoproteins.

Dargatz, D.A.; Garry, F.B.; Traub-Dargatz. J.L. An introduction to biosecurity of cattle operations. Veterinary Clinics of North America, Food Animal Practice. 2002. 18 (1) 1-5.
NAL Call Number:  SF601 V535
Descriptors:  etiology, animal health, brucellosis, cattle diseases, cattle farming, disease prevention, foot and mouth disease, FMD, Mycobacterium tuberculosis, biosecurity.

Delafosse, A.; Goutard, F.; Thebaud, E.  Epidemiologie de la tuberculose et de la brucellose des bovins en zone periurbaine d'Abeche, Tchad[Epidemiology of bovine tuberculosis and brucellosis on the periphery of Abeche, Chad.] Revue d'Elevage et de Medecine Veterinaire des Pays Tropicaux. 2002, 55 (1) 5-13.  Note:  In French with English and Spanish summaries.    
NAL Call Number: 41.8 R3262
Descriptors: dairy cattle, bovine brucellosis and tuberculosis,  age groupings, brucellosis, disease prevalence and control, disease transmission, epidemiology, herd risk factors, Mycobacterium avium, Mycobacterium bovis, Chad. 

Doherty, M.L.; Cassidy, J.P.  New perspectives on bovine tuberculosis.  Veterinary Journal.  Mar 2002. 163 (2) 109-110. ISSN: 1090-0233
NAL Call Number:  SF601.V484
Descriptors:  cattle, Mycobacterium bovis, tuberculosis, disease control.

Freitas, J. de A.; Panetta, J.C.  Some epidemiological aspects of tuberculosis in water buffaloes in the Amazon basin of Brazil.  Buffalo Bulletin.  2002; 21 (4): 75-82.  ISSN:  0125-6726
Descriptors:  water buffalo, slaughter animal survey for diseases, Mycobacterium bovis, gender differences, climate effects, nutritional value, age, disease transmission, Marajo Island farms, Para, Brazil.

Frolich, K.; Thiede, S.; Kozikowski, T.; Jakob, W.  A review of mutual transmission of important infectious diseases between livestock and wildlife in Europe.  In:  E.P.J. Gibbs and B.H. Bokma, B.H. (editors).  The Domestic Animal/Wildlife Interface: Issues for Disease Control, Conservation, Sustainable Food Production, and Emerging Diseases Conference and Workshop Organised by the Society for Tropical Veterinary Medicine and the Wildlife Diseases Association Wildlife and Livestock, Disease and Sustainability: What Makes Sense? Pilanesberg National Park, South Africa, 22-27July,-2001.  Annals of New York Academy of Sciences Vol. 969 2002; 4-13.  ISBN:  1573314382
Descriptors:  wild red foxes, oral vaccination against rabies, zoonotic disease such as hog cholera in wild boar and domestic pigs, cattle and roe deer get BVD, myxomatosis and rabbit hemorrhagic disease in rabbits, Mycobacterium bovis in cattle, wild boars, badgers, deer, viral diseases, bacterial disease, serological surveys, various European countries.

Garcia de Viedma, D.; del S. Diaz Infantes, M.; Lasala, F.; Chaves, F.; Alcala, L.; Bouza, E.; del S. Diaz Infantes, M. New real-time PCR able to detect in a single tube multiple rifampin resistance mutations and high-level isoniazid resistance mutations in Mycobacterium tuberculosis.  Journal of Clinical Microbiology. 2002. 40 (3) 988-995.
NAL Call Number:  QR46.J6
Descriptors:  antituberculous agents, drug resistance, isoniazid, mutations, polymerase chain reaction, rifampicin, strains, Mycobacterium tuberculosis.

Garnett, B.T.; Delahay, R.J.; Roper, T.J. Use of cattle farm resources by badgers (Meles meles) and risk of bovine tuberculosis (Mycobacterium bovis) transmission to cattle. Proceedings of the Royal Society of London. Series B, Biological Sciences. July 22, 2002. 269 (1499) 1487-1491. ISSN: 0962-8452
NAL Call Number:  501 L84B
Descriptors:  cattle, badgers, Meles meles, disease transmission, cattle housing, feeds, contamination, Mycobacterium bovis.

Hancox, M. The great badgers and bovine TB debate.  Journal of Agricultural Science. 2002, 139 (2) 223-226.  ISSN: 0021-8596    
NAL Call Number: 10 J822
Descriptors: badgers, cattle, wildlife disease reservoir, disease control program, public health risks,  risk assessment, tuberculosis, Mycobacterium tuberculosis, zoonoses.

Hasegawa, N.; Miura, T.; Ishii, K.; Yamaguchi, K.; Lindner, T.H.; Merritt, S.; Matthews, J.D.; Siddiqi, S.H. New simple and rapid test for culture confirmation of Mycobacterium tuberculosis complex: a multicenter study. Journal of Clinical Microbiology. 2002, 40 (3) 908-912.
NAL Call Number:  QR46.J6
Descriptors:  antigens, bacterial growth, rapid diagnostic methods, Mycobacterium bovis, Mycobacterium tuberculosis complex, Mycobacterium africanum, MPB64 antigen, sensitivity, specificity.

Hauser, R.; Hadorn, D.; Rufenacht, J.; Stark, K.  Examens par sondages permettant d'etablir que la Suisse est indemne de certaines epizooties. Nouvelle methode.  [Documentation on the free-of-disease situation with active surveillance in Switzerland. New approach.] Epidemiologie et Sante Animale. 2002, No.42, 81-87.  ISSN: 0754-2186  Note:  In French with an English summary.
Descriptors:  disease eradication, brucellosis, tuberculosisi, IBR, EBL, active surveillance, data gathering, sampling, simulation model, animal health, Aujeszky’s disease, risk-based approach, Mycobacterium tuberculosis, pigs, Switzerland. 

Jackson, R. Veterinary epidemiology in New Zealand: a 50-year perspective.  New Zealand Veterinary Journal. 2002. 50 (3, Supplement) 13-16.
NAL Call Number:  41.8 N483
Descriptors:  animal diseases, computer software, epidemiology, pets, tuberculosis, cattle, pigs New Zealand.

Kaneene, J.B.; Bruning-Fann, C.S.; Granger, L.M.; Miller, R.; Porter-Spalding, B.A. Environmental and farm management factors associated with tuberculosis on cattle farms in northeastern Michigan. Journal of the American Veterinary Medical Association. Sept 15, 2002. 221 (6) 837-842. ISSN: 0003-1488
NAL Call Number:  41.8 AM3
Descriptors:  cattle, farms, tuberculosis, Mycobacterium bovis, farm management, environmental factors, risk factors, wild animals, disease prevalence, livestock numbers, ponds, streams, Michigan.

Kaneene, J.B.; VanderKlok, M.; Bruning-Fann, C.S.; Palmer, M.V.; Whipple, D.L.; Schmitt, S.M.; Miller, R.A. Prevalence of Mycobacterium bovis infection in cervids on privately owned ranches.  Journal of the American Veterinary Medical Association. 2002. 220 (5) 656-659. ISSN: 0003-1488
NAL Call Number:  41.8 AM3
Descriptors:  analytical methods, diagnosis, diagnostic techniques, disease prevalence, epidemiology, tuberculosis, Cervidae, coyotes, deer, tuberculosis, Mycobacterium bovis, wildlife, slaughter and skin testing, disease transmission, Michigan.

Kennedy, H.E.; Welsh, M.D.; Bryson, D.G.; Cassidy, J.P.; Forster, F.I.; Howard, C.J.; Collins, R.A.; Pollock, J.M. Modulation of immune responses to Mycobacterium bovis in cattle depleted of WC1+ gammadelta T cells.  Infection and Immunity. Mar 2002. 70 (3) 1488-1500. ISSN: 0019-9567
NAL Call Number:  QR1.I57
Abstract:  It is accepted that cell-mediated immune responses predominate in mycobacterial infections. Many studies have shown that CD4(+) T cells produce Th1 cytokines, such as gamma interferon (IFN-gamma), in response to mycobacterial antigens and that the cytolytic activity of CD8(+) cells toward infected macrophages is important. However, the extent and manner in which gammadelta T cells participate in this response remain unclear. In ruminants, gammadelta T cells comprise a major proportion of the peripheral blood mononuclear cell population. We have previously shown that WC1(+) gammadelta T cells are involved early in Mycobacterium bovis infection of cattle, but their specific functions are not well understood. Here we describe an in vivo model of bovine tuberculosis in which the WC1(+) gammadelta T cells were depleted from the peripheral circulation and respiratory tract, by infusion of WC1(+)-specific monoclonal antibody, prior to infection. While no effects on disease pathology were observed in this experiment, results indicate that WC1(+) gammadelta T cells, which become significantly activated (CD25(+)) in the circulation of control calves from 21 days postinfection, may play a role in modulating the developing immune response to M. bovis. WC1(+)-depleted animals exhibited decreased antigen-specific lymphocyte proliferative response, an increased antigen-specific production of interleukin-4, and a lack of specific immunoglobulin G2 antibody. This suggests that WC1(+) gammadelta TCR(+) cells contribute, either directly or indirectly, toward the Th1 bias of the immune response in bovine tuberculosis--a hypothesis supported by the decreased innate production of IFN-gamma, which was observed in WC1(+)-depleted calves.
Descriptors:  T lymphocytes, lymphocyte transformation, cell mediated responses, calves, tuberculosis, Mycobacterium bovis.

Kim, J.H.; Sohn, H.J.; Kang, K.I.; Kim, W.I.; An, J.S.; Jean, Y.H. Mycobacterium bovis infection in a farmed elk in Korea. Journal of  Veterinary Science.  Sept 2002. 3 (3) 163-166. ISSN: 1229-845X
URL:
http://www.ksvs.or.kr
NAL Call Number:  SF604.J68
Descriptors:
  Cervus elaphus, game farming, animal diseases, Mycobacterium bovis, tuberculosis, case reports, postmortem examinations, lungs, lymph nodes, histopathology, abscesses, granuloma, Korea Republic.

Krayc, B. (ed) ; Schonthaler, D. Tagungsbericht 1. Fachtagung fur Ziegenzuchter und halter zum Thema Ziegenzucht und Ziegenhaltung, 12. November und 13. November 2002, BAL Gumpenstein, Irdning, Austria. [Conference report. 1. Specialist conference for goat breeders and keepers on the theme of goat breeding and management. 12 and 13 November 2002 at BAL Gumpenstein, Austria.] Published by Bundesanstalt fur alpenlandische Landwirtschaft Gumpenstein; Irdning; Austria  2002, 50 pp. Note:  In German. A proceedings that includes 12 papers on a variety to topics.
Descriptors: breeding, EU, nutritional value of goat products, goats milk, grazing in alpine areas, feeding, Tauern Pied, tuberculosis, mastitis, Johne’s disease, brucellosis, etc.

Kwong, L.S.; Hope, J.C.; Thom, M.L.; Sopp, P.; Duggan, S.; Bembridge, G.P.; Howard, C.J.  Development of an ELISA for bovine IL-10.  Veterinary Immunology and Immunopathology.  2002; 85 (3/4): 213-223.  ISSN: 0165-2427
URL:  http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number:  SF757.2.V38
Abstract:  The objective of the study was to develop an assay for bovine IL-10 that could be applied to analyses of immune responses and advance understanding of a variety of diseases of cattle.  Recombinant bovine IL-10 (rbo IL-10) was transiently expressed in Cos-7 cells and shown to inhibit the synthesis of IFNgamma by bovine cells stimulated with antigen in vitro.  Mice were immunised with a plasmid containing a cDNA insert encoding rbo IL-10 and inoculated with rbo IL-10.  A number of monoclonal antibodies (mab) were generated that reacted with rbo IL-10 in an ELISA.  Some of these mab neutralised the ability of rbo IL-10 to inhibit IFNgamma synthesis by antigen-stimulated bovine cells.  A pair of mabs was identified that together could be used to detect both recombinant and natural bovine IL-10 present in supernatant of PBMC stimulated with ConA.  A luminescent detection method was applied to the ELISA making it more sensitive.  Using this method native IL-10 was detected in supernatants of PBMC, diluted blood and undiluted blood from cattle immunised with Mycobacterium bovis BCG or ovalbumin and incubated in vitro with antigen indicating the applicability of the assay to a number of in vitro culture systems.
Descriptors:  cattle, interleukin 10, ELISA, monoclonal antibodies, interferon, recombinant DNA, complementary DNA, protein synthesis, inhibition.

Lis, H. Wyniki badania sanitarno-weterynaryjnego zwierzat rzeznych i miesa w Polsce w 2000 r. [Results of veterinary inspection of slaughtered animals and meat in Poland in 2000.] Medycyna Weterynaryjna. 2002. 58 (4) 267-269. Note:  In Polish with an English summary.
NAL Call Number:  41.8 M463
Descriptors:  calves, carcasses, cysticercosis, diagnosis, echinococcosis, emaciation, food safety, jaundice, lesions, leukemia, liver flukes, meat, meat inspection, neoplasms, septicaemia, slaughter, trichinosis, tuberculosis, horses, Mycobacterium tuberculosis, pigs, sheep, Trichinella, Poland.

Livingstone, P.; McInnes, J.; Carter, C.; Ryan, T.; Hancox, N.  Controlling bovine tuberculosis in cattle where there is a wildlife source of infection. Bulletin of the International Dairy Federation. 2002. No. 372, 33-42. Note:  A fresh perspective for managing milk-borne diseases. Proceedings of the Animal Health Conference, IDF World Dairy Summit 2001, Auckland, New Zealand, International Dairy Federation, Brussels, Belgium.
NAL Call Number:  44.9 In82B
Descriptors:  costs, dairy cattle, dairy herds, disease control, disease transmission, disease vectors, tuberculosis, vector control, wild animals, wild pigs, cattle, Cervus elaphus, ferrets, Mycobacterium tuberculosis, pigs, red deer, Trichosurus vulpecula, bovine tuberculosis, New Zealand.

Lysenko, A.P.; Rumachik, I.I.  Application of novel methods to differentiate reactions to tuberculin in cattle.  Veterinarnaya Nauka Proizvodstvu.  2002; (36): 76-84.  Note:  In Russian.  
Descriptors:  cattle, Mycobacterium bovis, Mycobacterium tuberculosis, differential diagnosis, tuberculin.

Michel, Anita L. Implications of tuberculosis in African wildlife and livestock.  Annals of the New York Academy of Sciences. 2002; 969: 251-255  ISSN:  0077-8923    
NAL Call Number: 500 N484
Descriptors:  wild animals, livestock animals, mammals, literature review, Mycobacterium bovis,  Ethiopian.  

Michel, A.L.  Implications of tuberculosis in African wildlife and livestock.   In:  E.P.J. Gibbs and B.H. Bokma, B.H. (editors).  The Domestic Animal/Wildlife Interface: Issues for Disease Control, Conservation, Sustainable Food Production, and Emerging Diseases Conference and Workshop Organised by the Society for Tropical Veterinary Medicine and the Wildlife Diseases Association Wildlife and Livestock, Disease and Sustainability: What Makes Sense? Pilanesberg National Park, South Africa, 22-27 July, 2001.  Annals of New York Academy of Sciences Vol. 969. 2002: 251-255.  ISBN:  1573314382
Descriptors: cattle, wild animals, Mycobacterium bovis, Papio ursinus, Potamochoerus porcus, African buffalo, Syncerus caffer, Tragelaphus scriptus, Tragelaphus strepsiceros, Panthero leo, Crocuta crocuta, disease control, disease transmission between wildlife species and domestic livestock.

Miller, J.M.; Jenny, A.L.; Payeur, J.B. Polymerase chain reaction detection of Mycobacterium tuberculosis complex and Mycobacterium avium organisms in formalin-fixed tissues from culture-negative ruminants. Veterinary Microbiology. June 5, 2002. 87 (1) 15-23. ISSN: 0378-1135
NAL Call Number:  SF601.V44
Abstract:   In the US eradication program for bovine tuberculosis, a definitive diagnosis depends on the isolation of Mycobacterium bovis. However, in some cases bacterial culture is unsuccessful, even though the tissue is considered suspicious by histopathology because granulomatous lesions and acid-fast organisms are present. The purpose of this study was to determine if polymerase chain reaction (PCR) tests on formalin-fixed tissue would successfully identify the organisms observed in suspect lesions from culture-negative animals. Diagnostic laboratory records were used to select paraffin blocks of tissue from 102 ruminants that had suspect microscopic lesions but no bacterial isolation. Sections from these blocks were examined with PCR primers for IS6110 to detect Mycobacterium tuberculosis complex infection, or with 16S ribosomal RNA and IS900 primers for detection of Mycobacterium avium. The PCR tests successfully identified a mycobacterial infection in 58 of 102 tissues, including 41 M. tuberculosis complex and 17 M. avium (11 subspecies paratuberculosis). These results demonstrate that PCR testing of formalin-fixed tissue, in combination with bacterial culture, may increase the effectiveness of laboratory diagnostic efforts to detect and identify the most common mycobacterial diseases of ruminants.
Descriptors:
  Mycobacterium tuberculosis, Mycobacterium avium, polymerase chain reaction, PCR, detection, diagnosis, formaldehyde, lesions, ribosomal RNA.

Mota, P.M.P.C.; Lobato, F.C.F.; Assis, R.A.; Lage, A.P.; Parreiras, P.M.; Leite, R.C. Ocorrencia de tuberculose em rebanhos bubalinos (Bubalus bubalis var. bubalis-Linneus, 1758) no Municipio de Parintins, Amazonas. [Occurrence of tuberculosis in herds of buffalos of Amazonas State, Brazil.] Arquivo Brasileiro de Medicina Veterinaria e Zootecnia. 2002, 54 (4) 441-443. Note:  In Portuguese with an English summary.
NAL Call Number:  SF604 A76
Descriptors:  diagnosis, herds, lymph nodes, tuberculosis, buffalo, Bubalus bubalis, Mycobacterium bovis, Amazonas, Brazil.

Palmer, M.V.; Waters, W.R.; Whipple, D.L.  Aerosol delivery of virulent Mycobacterium bovis to cattle. Tuberculosis. 2002, 82 (6) 275-282.  
Descriptors: cattle calves, 2 strains of Mycobacterium bovis, HC2005T, isolate 1315 from deer, aerosol delivery model, tuberculosis infection, tuberculous lesions, lungs, lymph nodes, virulence, no strain differences.

Pavlik, I.; Ayele, W.Y.; Parmova, I.; Melicharek, I.; Hanzlikova, M.; Kormendy, B.; Nagy, G.; Cvetnic, Z.; Ocepek, M.; Fejzic, N.; Lipiec, M. Incidence of bovine tuberculosis in cattle in seven Central European countries during the years 1990-1999. Veterinarni Medicina. 2002. 47 (2-3) 45-51.
NAL Call Number:  41.9 C333
Descriptors:  epidemiology, outbreaks, skin tests, cattle, bovine tuberculosis, Mycobacterium, Bosnia Hercegovina, Croatia, Central Europe, Czech Republic, Hungary, Poland, Slovakia, Slovenia.

Pavlik, I.; Machackova, M.; Ayele, W.Y.; Lamka, J.; Parmova, I.; Melicharek, I.; Hanzlikova, M.; Kormendy, B.; Nagy,G.; Cvetnic, Z.; Ocepek, M.; Lipiec, M.  Incidence of bovine tuberculosis in wild and domestic animals other than cattle in six Central European countries during 1990-1999.  Veterinarni Medicina. 2002. 47 (5) 122-131.
NAL Call Number:  41.9 C333
Descriptors:  disease prevalence, disease transmission, domestic animals, epidemiology, game animals, tuberculosis, sheep, boars, wild goats, Bison bison, Bison bonasus, Camelus bactrianus, Bactrian camels, Casuarius, cassowary, Cervus elaphus, Connochaetes taurinus, dogs, zoo animals, Felis concolor, puma, sitatungas, elands, gnu, Vietnamese pot-bellied pig. Giraffa camelopardalis, giraffes, Mycobacterium bovis, pigs, red deer, sheep, Tapirus terrestris, Taurotragus oryx, Tragelaphus, Central Europe.

Pavlik, I.; Bures, F.; Janovsky, P.; Pecinka, P.; Bartos, M.; Dvorska, L.; Matlova, L.; Kremer, K.; van Soolingen, D.  The last outbreak of bovine tuberculosis in cattle in the Czech Republic in 1995 was caused by Mycobacterium bovis subspecies caprae. Veterinarni Medicina. 2002. 47 (9) 251-263.
NAL Call Number:  41.9 C333
Descriptors:
Mycobacterium bovis ssp caprae bovine tuberculosis, 14 year old cow, case study, herd health, source, Czech Rebuplic.

Pavlik, I.; Dvorska, L.; Matlova, L.; Svastova, P.; Parmova, I.; Bazant, J.; Veleba, J.  Mycobacterial infections in cattle in the Czech Republic during 1990-1999.  Veterinarni Medicina. 2002. 47 (9) 241-250.
NAL Call Number:  41.9 C333
Descriptors:  cattle, tuberculin testing, post-mortem diagnosis, bovine tuberculosis, skin testing, tuberculin, tuberculosis lesions, Mycobacterium bovis, disease incidence data, Czech Republic.

Payeur, Janet B.; Church, S.; Mosher, L.; Robinson-Dunn, B.; Schmitt, S.; Whipple, D.   Bovine tuberculosis in Michigan wildlife.  Annals of the New York Academy of Sciences. 2002; 969: 259-261 ISSN:  0077-8923    
NAL Call Number: 500 N484
Descriptors:  wild animals, bacterial diseases, Mycobacterium bovis, prevalence in wildlife and livestock, wild animal as disease reservoirs, Michigan.

Perez, A.; Debenedetti, R.; Martinez-Vivot, M.; Bernardelli, A.; Torres, P.; Ritacco,V.  Tendencia de la tuberculosis porcina y validez de la inspeccion bromatologica para su deteccion en areas de produccion intensiva de Argentina. [Swine tuberculosis validity of the macroscopic inspection at slaughter level.]  Revista de Medicina Veterinaria, Buenos Aires. 2002. 83 (1) 14-18. Note:  In Spanish with an English summary.
NAL Call Number:  41.8 B86
Descriptors:  bacteriology, carcass quality, carcasses,  post-slaughter diagnosis, digestive tract, disease prevalence, histopathology, macroscopic meat inspection, slaughter, tuberculosis, Mycobacterium bovis, pigs, Argentina.

Perez, A.M.; Ward, M.P.; Ritacco, V. Simulation model evaluation of bovine tuberculosis-eradication strategies in Argentine dairy herds.  Preventive Veterinary Medicine. Aug 30, 2002. 54 (4) 351-360. ISSN: 0167-5877
NAL Call Number:  SF601.P7
Descriptors:  dairy herds, cattle, tuberculosis, simulation models, disease control, infection, culling of diseased animals, diagnostic techniques and tests, epidemiology, Mycobacterium bovis, Argentina.

Perez, A.M.; Ward, M.P.; Charmandarian, A.; Ritacco, V. Simulation model of within-herd transmission of bovine tuberculosis in Argentine dairy herds.  Preventive Veterinary Medicine. Aug 30, 2002. 54 (4) 361-372. ISSN: 0167-5877
NAL Call Number:  SF601.P7
Descriptors:  dairy herds, cattle, Mycobacterium bovis, disease transmission, simulation models, tuberculosis, estimation of disease prevalence, infectivity, Argentina.

Perez, A.M.; Ward, M.P.; Torres, P.; Ritacco, V.; Durr, P. (ed.); Pfeiffer, D. Use of spatial statistics and monitoring data to identify clustering of bovine tuberculosis in Argentina. Preventive Veterinary Medicine. 2002. 56 (1) 63-74. Note: Spatial Epidemiology Research Papers prepared for and presented at the GISVET Conference, Lancaster University, England, 10-14 September 2001.
NAL Call Number:  SF601 P7
Descriptors:  dairy cattle, cattle, disease distribution, epidemiology, geographical/spatial distribution, statistical analysis, tuberculosis, bovine tuberculosis, Mycobacterium, Argentina.

Phillips, C.J.C.; Foster, C.R.W.; Morris, P.A.; Teverson, R. Genetic and management factors that influence the susceptibility of cattle to Mycobacterium bovis infection.  Animal Health Research Reviews. 2002. 3 (1) 3-13.
NAL Call Number:  SF601 A547
Descriptors:  animal husbandry, disease control, disease resistance, disease transmission, genetic factors, genetic variation, genotype, environment interaction, immune response, immunity, immunostimulation, risk assessment, risk factors, risk reduction, susceptibility, tuberculosis, vaccination, cattle, Mycobacterium bovis.

Pinto, P.S.A.; Faria, J.E.; Viloria, M.I.V.; Bevilacqua, P.D.  Exame microbiologico da tuberculose como subsidio a inspecao post-mortem de bovinos.  [Bacteriological analysis of tuberculosis as a support to bovine postmortem inspection.]  Revista Brasileira de Saude e Producao Animal.  2002; 3 (1): 10-15.  ISSN:  1519-9940.  Note:  In:  Portuguese with an English summary.
Descriptors:  beef cattle, humans, Mycobacterium bovis, animal pathology, disease transmission, disease prevalence, disease surveys, diagnosis, diagnostic techniques, disease transmission, epidemiological surveys, epidemiology, microbial contamination of food, meat hygiene, meat inspection, postmortem examinations, tuberculin, tuberculosis, zoonoses.

Pollock, J.M.; Neill, S.D. Mycobacterium bovis infection and tuberculosis in cattle.  Veterinary Journal.  Mar 2002. 163 (2) 115-127. ISSN: 1090-0233
URL:
http://intl.elsevierhealth.com/journals/tvjl/
NAL Call Number:  SF601.V484
Abstract:  This review considers the possible events that can occur when cattle are exposed to Mycobacterium bovis and, where appropriate, draws on principles accepted for tuberculosis infection in humans and laboratory animal models. Consideration is given to the many complex factors which influence the outcome of challenge with tubercle bacilli. These include features inherent to the Mycobacterium, the host and the environment. It is apparent that clinical disease probably occurs only in a relatively small, but undetermined, proportion of cattle that are exposed to M. bovis. The majority of animals may clear infection or control the bacilli, possibly in a condition of latency. It is concluded that a better understanding of the dynamics of the events following M. bovis exposure and subsequent infection in cattle would be of significant benefit in developing new tools appropriate for disease control and to designing optimal approaches for their application.
Descriptors:  cattle, Mycobacterium bovis, tuberculosis, pathogenesis, disease control, infection, shedding, immune system, immune response, latent infections, literature review.

Pons, L. An easy, inexpensive test detects tuerculosis in livestock and wildlife.  Agricultural Research.  Nov 2002. 50 (11) 20-21. ISSN: 0002-161X
URL:
http://www.ars.usda.gov/is/AR/
NAL Call Number:  1.98 Ag84
Descriptors:  tuberculosis, animal diseases, livestock, wildlife, testing and disease control, Mycobacterium bovis, blood sampling, diagnostic techniques, assays, USA.

Prodinger, W.M.; Eigentler, A.; Allerberger, F.; Schonbauer, M.; Glawischnig, W. Infection of red deer, cattle, and humans with Mycobacterium bovis subsp. caprae in western Austria. Journal of Clinical Microbiology. June 2002. 40 (6) 2270-2272. ISSN: 0095-1137
NAL Call Number:  QR46.J6
Descriptors:  tuberculosis, red deer, cattle, zoonotic aspects, epidemiology, disease transmission, Mycobacterium bovis ssp. caprae.

Ramsey, D.; Spencer, N.; Caley, P.; Efford, M.; Hansen, K.; Lam, M.; Cooper, D.  The effects of reducing population density on contact rates between brushtail possums: implications for transmission of bovine tuberculosis. Journal of Applied Ecology. 2002. 39 (5) 806-818.
NAL Call Number:  410 J828
Descriptors:  animal behavior, animal ecology, breeding season, contacts, disease transmission, mating behavior, estrus, population density, reservoir hosts, tuberculosis, wild animals, Mycobacterium bovis, Trichosurus vulpecula, New Zealand.

Rogers, L.M.; Hounsome, T.D.; Cheeseman, C.L. An evaluation of passive integrated transponders (PITs) as a means of permanently marking Badgers (Meles meles).  Mammal Review. 2002, 32 (1) 63-65. ISSN:  0305-1838    
NAL Call Number: QL700.M24
Descriptors: badgers, cattle, Meles meles, Mycobacterium bovis, identification, markers, sentinel animals, sentinel surveillance, transponders, tuberculosis,
England.

Schmitt, Stephen M.; O'Brien, Daniel J.; Bruning-Fann, Colleen S.; Fitzgerald, Scott D. Bovine tuberculosis in Michigan wildlife and livestock. Annals of the New York Academy of Sciences. 2002; 969: 262-268  ISSN: 0077-8923    
NAL Call Number: 500 N484
Descriptors:  wild animals, bacterial diseases, Mycobacterium bovis, prevalence in wildlife and livestock, Michigan.

Schneider, M.; Molinarr,R.; Magnano,G.; Giraudo,J.; Escalarea,M. Tuberculosis bovina en campos con saneamiento avanzado. [Bovine tuberculosis in farms with advanced sanitary schemes.] Veterinaria Argentina. 2002, 19 (189) 652-660.   Note:  In Spanish with an English summary.    
NAL Call Number: SF604.V463
Descriptors: dairy cattle, Mycobacterium, eradication program, diagnostic techniques, disease control and prevention program, tuberculosis,
Argentina.

Seva, J.; Menchen, V.; Navarro, J.A.; Pallares, F.J.; Villar, D.; Vasquez, F.; Bernabe, A. Caprine tuberculosis eradication program: an immunohistochemical study. Small Ruminant Research. 2002. 46 (2-3) 107-114. ISSN: 0921-4488
NAL Call Number:  SF380.I52
Abstract:  We studied the evolution of different forms of tuberculosis in herds which are periodically submitted to the comparative tuberculin intradermal reaction (CTID) test within the Caprine Tuberculosis Eradication Program in the Region of Murcia (Spain).  In the study, 135 goats with tuberculosis from different herds were diagnosed by histopathological and immunocytochemical techniques.  Most animals (58 of the 135) were in the primary complex of tuberculosis, with few or no acid-fast bacilli (AFB) and mycobacterial antigens.  Generalized tuberculosis was present in 31 of the 135 animals, and the numbers of bacilli and positive immunocytochemical particles were higher than in animals with the primary complex.  Postprimary phase was observed in 44 of the 135 animals, and the number of bacilli and positive immunocytochemical particles increased in proportion to the extent and gravity of the necrotic foci.  Tuberculous pneumonia with a high number of bacilli was only observed in two goats.  Extrapulmonary tuberculosis was present with lesions in the intestines (60/135), liver (80/135) and spleen (77/135).  This study confirmed that the Caprine Tuberculosis Eradication Program is resulting in fewer animals with postprimary tuberculous processes, and a corresponding increase in the number of primary complex and generalized tuberculosis.
Descriptors: 
control programs, disease control, extrapulmonary tuberculosis, intestines, liver, immunohistochemistry, lesions, spleen, tuberculosis, goats, Mycobacterium bovis, Spain.

Skjerve, E.; Smulders, F.J.M. (ed.); Collins, J.D. Emerging pathogenic bacteria of special interest: epidemiological concerns.  Food Safety Assurance and Veterinary Public Health, Volume 1. Food Safety Assurance in the Pre-harvest Phase. 2002. p. 141-152. Wageningen Academic Publishers; Wageningen; Netherlands.    
NAL Call Number: IPSP12358

Descriptors:  animal health, drug resistance, epidemiology, food contamination, food production, food safety, foodborne diseases, public health risk assessment, salmonellosis, tuberculosis zoonoses, Bacillus cereus, Escherichia coli, Mycobacterium avium ssp. paratuberculosis, Salmonella enteritidis, Salmonella typhimurium.

Spedding, A. Review of the year, June 2001 - May 2002.  Journal of the Royal Agricultural Society of England. 2002, 163: 188-194.    
NAL Call Number: 10 F81

Descriptors: cattle diseases, livestock animals, agricultural policy, agricultural prices, BSE. Bovine spongiform encephalopathy, climatic change; disease prevalence, economic impact, FMD, foot and mouth disease; livestock, subsidies, bovine tuberculosis, European Union Countries,
UK. 

Sulieman, M.S.; Hamid, M.E.  Identification of acid fast bacteria from caseous lesions in cattle in Sudan.  Journal of Veterinary Medicine. Series B. 2002, 49 (9) 415-418.  ISSN: 0931-1793    
NAL Call Number: 41.8 Z52
Descriptors:  cattle, Mycobacterium avium, Mycobacterium bovis, Mycobacterium farcinogenes, Mycobacterium tuberculosis, Nocardia, caseous lesions, post-slaughter, lymph nodes, acid-fast bacteria strains,
Sudan.

Toma, B.; Pouillot, R.; Sanaa, M.  Appreciation quantitative du risque: exemples d'approche deterministe. [Quantitative risk assessment: examples of a deterministic approach.] Epidemiologie et Sante Animale. 2002, No.41, 85-94. ISSN: 0754-2186  Note: In French with an English summary.
Descriptors: cattle, Brucella, Mycobacterium, tuberculosis, brucellosis, deterministic models, disease transmission, imported infections, international trade, livestock, mathematical models, risk assessment.

Trautwein G.  Erkennung und Bekampfung der Rindertuberkulose. [Diagnosis and control of bovine tuberculosis.] Der Praktische Tierarzt. 2002. 83 (2) 164-164, 170. Note:  In German with an English summary.
NAL Call Number:  41.8 P88
Descriptors:  diagnosis, disease control, tuberculosis, cattle, Mycobacterium bovis.

Valente, C.; Cuteri, V.; Ausili, E.; Piersimoni, C. Evaluation of the Abbott LCx Mycobacterium tuberculosis assay for direct detection of Mycobacterium bovis in bovine tissue samples. Veterinary Research Communications. Jan 2002. 26 (1) 21-27. ISSN: 0165-7380
NAL Call Number:  SF601.V38
Descriptors:
  Mycobacterium tuberculosis, Mycobacterium bovis, detection, diagnostic techniques, evaluation, species differences, cattle, lymph nodes, histopathology, ligases.

Varga, J. Hazai szarvasmarha-allomanyaink mentesitese nehany fertozo betegsegtol. [Eradication of some diseases from cattle herds in Hungary.]  Magyar Allatorvosok Lapja. 2002. 124 (6) 327-332. Note:  In Hungarian with an English summary.
NAL Call Number:  41.8 V644
Descriptors:  cattle diseases, disease control, bovine leucosis, tuberculosis, brucellosis, diarrhea, FMD, foot and mouth disease, herpesvirus, Hungary.

Vordermeier, H.M.; Chambers, M.A.; Cockle, P.J.; Whelan, A.O.; Simmons, J.; Hewinson, R.G. Correlation of ESAT-6-specific gamma interferon production with pathology in cattle following Mycobacterium bovis BCG vaccination against experimental bovine tuberculosis. Infection and Immunity. 2002. 70 (6) 3026-3032. ISSN: 0019-9567
NAL Call Number:  QR1.157
Abstract:  Vaccine development and the understanding of the pathology of bovine tuberculosis in cattle would be greatly facilitated by the definition of immunological correlates of protection and/or pathology. To address these questions, cattle were vaccinated with M. bovis bacillus Calmette-Guerin (BCG) and were then challenged with virulent M. bovis. Applying a semiquantitative pathology-scoring system, we were able to demonstrate that BCG vaccination imparted significant protection by reducing the disease severity on average by 75%. Analysis of cellular immune responses following M. bovis challenge demonstrated that proliferative T-cell and gamma interferon (IFN-gamma) responses towards the M. bovis-specific antigen ESAT-6, whose gene is absent from BCG, were generally low in vaccinated animals but were high in all nonvaccinated calves. Importantly, the amount of ESAT-6-specific IFN-gamma measured by enzyme-linked immunosorbent assay after M. bovis challenge, but not the frequency of responding cells, correlated positively with the degree of pathology found 18 weeks after infection. Diagnostic reagents based on antigens not present in BCG, like ESAT-6 and CFP-10, were still able to distinguish BCG-vaccinated, diseased animals from BCG-vaccinated animals without signs of disease. In summary, our results suggest that the determination of ESAT-6-specific IFN-gamma, while not a direct correlate of protection, constitutes nevertheless a useful prognostic immunological marker predicting both vaccine efficacy and disease severity.
Descriptors:  BCG vaccine, cattle, calves, cell mediated immunity, immune response, ESAT-6-specific IFN gamma, ELISA, immunization, interferon, Mycobacterium bovis, tuberculosis, vaccination.

Walravens, K.; Marche, S.; Rosseels, V.; Wellemans, V.; Boelaert, F.; Huygen, K.; Godfroid, J.; Fossum, C. (ed.); Wattrang, E.  IFN-gamma diagnostic tests in the context of bovine mycobacterial infections in Belgium. Veterinary Immunology and Immunopathology. 2002. 87 (3-4) 401-406. ISSN: 0165-2427. Note: 6th International Veterinary Immunology Symposium, Ultuna Campus, Swedish University of Agricultural Sciences, Uppsala, Sweden, July 2001.
NAL Call Number:  SF757.2 V38
Abstract:   In countries where cattle tuberculosis caused by Mycobacterium bovis (Mbov) and paratuberculosis caused by Mycobacterium avium subsp. paratuberculosis (Mptb) are present, testing strategies for the Mbov eradication have to discriminate between these two infections. Present indirect tests are based on the analysis of the specific cellular immune response (DTH, IFN-gamma) against crude mycobacterial antigens (avian and bovine PPD). In this study, we compared the evolution of the IFN-gamma responses of animals experimentally infected with Mbov, Mptb, or inoculated with Mycobacterium phlei. Mbov inoculation induced a strong IFN-gamma response that allows rapid classification of the status of the animals following interpretation criteria set up by us. Experimental inoculation with M. phlei induced sensitization to mycobacterial antigens as detected by the IFN-gamma test but these reactions were of short duration, therefore, repeated testing allows us to define these animals as a specific reactors. IFN-gamma response induced after oral inoculation of calves with Mptb was of low intensity and ratio of responses measured against avian versus bovine PPD did not allow a clear diagnostic at least for the six first month of infection.
Descriptors:
  Mycobacterium avium ssp. paratuberculosis, Mycobacterium bovis, Mycobacterium phlei, cattle diseases, diagnosis, experimental infection, immune responses, interferon, IFN-gamma response, Belgium.

Walravens, K.; Wellemans, V.; Weynants, V.; Boelaert, F.; de Bergeyck, V.; Letesson, J.J.; Huygen, K.; Godfroid, J.  Analysis of the antigen-specific IFN-gamma producing T-cell subsets in cattle experimentally infected with Mycobacterium bovis.  Veterinary Immunology & Immunopathology.  2002; 84 (1/2): 29-41.  ISSN: 0165-2427
URL:  http://www.elsevier.com/wps/find/journalabstracting.cws_home/503319/abstracting
NAL Call Number:  SF757.2.V38
Abstract:  Three 10 months old cattle were infected by the intra-tracheal route with 10(6) cfu of a field strain of Mycobacterium bovis.  Blood samples were regularly collected for in vitro IFN-gamma production after antigenic stimulation.  Peripheral blood cells of infected animals produced IFN-gamma in response to crude M. bovis antigens (live and heat-inactivated BCG and protein-purified derivative (PPD)) 3-4 weeks after infection.  The ratio of the response to bovine PPD versus avian PPD indicated a specific sensitisation for M. bovis antigens.  Three months post-infection (PI), animals were culled and M. bovis was cultured from tubercle lesions.  At different time points, the frequency of specific M. bovis IFN-gamma producing CD4+, CD8+ and WC1+ T-cells in the peripheral blood was examined by flow cytometry.  Two colour immunofluorescence staining of intracellular IFN-gamma and bovine cell surface molecules showed that both CD4+ and CD8+, but not WC1+, T-cells produced IFN-gamma following stimulation with PPD, live or killed BCG. In two animals analysed, the relative percentage of circulating IFN-gamma producing CD8+ cells decreased between week 5 and week 9 PI.  The same evolution was not observed for IFN-gamma secreting CD4+ cells.  Magnetic positive selection of T-cells from infected animals showed that CD4+ T-cells produced specific IFN-gamma only in the presence of antigen presenting cells (ADCs).  Positively selected CD8+ T-cells secreted IFN-gamma only in the presence of recombinant human IL-2 and APCs. In vitro depletion of the CD4+ T-cells, but not the depletion of CD8+ or WC 1 + T-cells, resulted in abrogation of the specific IFN-gamma production showing the key role of this cell population for the specific.INF-gamma production.  
Descriptors:  cattle, Mycobacterium bovis, antigens, interferon, T-lymphocytes, experimental infections, lesions, CD4+-lymphocytes,  CD8+-lymphocytes, flow-cytometry, WCL+-lymphocytes.

Watson, C.W. An investigation into the possible relationships between BVD and TB in practice.  Cattle Practice. 2002. 10 (2) 101-103.
NAL Call Number:  SF961 C37
Descriptors:  beef cattle, cows, dairy cows, epidemiology, outbreaks, tuberculosis, vaccination, cattle, Mycobacterium bovis.

Wedlock, D.N.; Keen, D.L.; McCarthy, A.R.; Andersen, P.; Buddle, B.M. Effect of different adjuvants on the immune responses of cattle vaccinated with Mycobacterium tuberculosis culture filtrate proteins. Veterinary Immunology and Immunopathology. May 2002. 86 (1/2) 79-88. ISSN: 0165-2427
NAL Call Number:  SF757.2.V38
Abstract:  The development of improved vaccines for bovine tuberculosis is urgently required as a cost effective solution for control and eventual eradication of tuberculosis in domestic animals. Studies in small animal models of tuberculosis have shown that vaccination with culture filtrate proteins (CFP), prepared from Mycobacterium tuberculosis or M. bovis, can induce cellular immune responses and confer a level of protection against aerogenic challenge with virulent mycobacteria. As a first step in the development of a mycobacterial CFP vaccine for protection of cattle against bovine tuberculosis, the immune responses of cattle vaccinated with short-term culture filtrate proteins (ST-CFP) from M. tuberculosis and formulated with different adjuvants were compared with those vaccinated with bacille Calmette-Guerin (BCG). The adjuvants included dimethyldioctyldecyl ammonium bromide (DDA), diethylaminoethyl (DEAE)-dextran, and ST-CFP adsorbed onto polystyrene beads. Vaccination with ST-CFP/DEAE-dextran induced high levels of interleukin-2 (IL-2) but low levels of interferon-gamma (IFN-gamma) from whole-blood cultures stimulated with M. tuberculosis ST-CFP in comparison with the strong IFN-gamma and IL-2 responses induced after vaccination with BCG. ST-CFP/DEAE-dextran also induced a strong antigen-specific immunoglobulin antibody response with both immunoglobulin G1 (IgG1 and IgG2 isotypes. Vaccination with ST-CFP/beads induced a weak IgG1-biased antibody response but no IFN-gamma or IL-2 response. DDA did not induce significant immune responses in animals vaccinated with ST-CFP. In comparison to the moderate delayed-type hypersensitivity (DTH) responses induced by vaccination with subcutaneous BCG, none of the ST-CFP vaccines induced a significant DTH response to either M. tuberculosis ST-CFP or bovine purified protein derivative (PPD). While the ST-CFP vaccines used in this study have not induced strong antigen-specific cellular immune responses in cattle comparable to those induced by BCG, they are immunogenic in cattle and it may be possible to overcome this problem by using adjuvants that more effectively promote IFN-gamma responses in this species.
Descriptors:  cattle, Mycobacterium tuberculosis, Mycobacterium bovis, adjuvants, immune response, vaccination, vaccines, culture filtrates, cell mediated immunity, humoral immunity, tuberculosis, interferon, interleukin-2, dimethyldioctyldecyl ammonium bromide, diethylaminoethyl dextran, subunit vaccines.

White, P.; Smulders, F.J.M. (ed.); Collins, J.D. The disclosure of tuberculous lesions at slaughter in cattle from attested herds in CO. Monaghan in 1995. Food Safety Assurance  and Veterinary Public Health, Volume 1. Food Safety Assurance in the Pre-harvest Phase. 2002. p. 302-305. Wageningen Academic Publishers; Wageningen; Netherlands. ISBN:  90-769980-51    
NAL Call Number: IPSP12358
Descriptors:  lesions, meat quality, tuberculosis, cattle, Mycobacterium tuberculosis, Irish Republic.

Wilson, P.R. Advances in health and welfare of farmed deer in New Zealand.  New Zealand Veterinary Journal. 2002. 50 (3, Supplement) 105-109.
NAL Call Number:  41.8 N483
Descriptors:  animal health, animal welfare, antlers, capture of animals, deer farming, malignant catarrhal fever, mortality from tuberculosis, Mycobacterium, New Zealand. 

Yamamoto, S.; Yamamoto,T.; Nojima,Y.; Umemori, K.; Phalen, S.; McMurray, D.N.; Kuramoto, E.; Iho, S.; Takauji, R.; Sato, Y.; Yamada, T.; Ohara, N.; Matsumoto, S.; Goto, Y.; Matsuo, K.; Tokunaga, T. Discovery of immunostimulatory CpG-DNA and its application to tuberculosis vaccine development. Japanese Journal of Infectious Diseases. 2002. 55 (2) 37-44. Note:  In English.
Descriptors:  adjuvants, BCG vaccine, biotechnology, DNA vaccine development, molecular genetics, immunostimulants, nucleotide sequences, reviews, Mycobacterium bovis BCG strain, Mycobacterium tuberculosis, antineoplastic properties.

2001

Aldwell, F. E.; Wedlock, D.N.; Slobbe, L.J.; Griffin, J.F.T.; Buddle, B.M.; Buchan, G.S.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. In vitro control of Mycobacterium bovis by macrophages.  Tuberculosis. 2001. 8 (1-2) 115-123. Note:  Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  cattle, deer, mice, marsupials, ferrets, growth, host range, in vitro testing, alternatives to animal testing, inhibition, interferon, macrophages, lungs, lipopolysaccharides, macrophage activation, Mycobacterium bovis, Mycobacterium bovis BCG, Mycobacterium tuberculosis.

Anonomyous. Policy in limbo. Veterinary Record. Aug 11, 2001. 149 (6) 161. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  tuberculosis in cattle, disease control policies, Mycobacterium bovis, UK.

Anonomyous. State veterinary activity: challenges faced and the challenges to come. Veterinary Record.  June 9, 2001. 148 (23) 701-702. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  animal health, disease surveys, outbreaks, swine fever, tuberculosis, Mycobacterium, transport of animals, disease control, Great Britain.

Anonymous. Stretched to the limit. Veterinary Record.  Jan 20, 2001. 148 (3) 61. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle tuberculosis, Mycobacterium, disease control, badgers, culling, UK.

Avylov, Ch. Problems of rat control on pig farms. Svinovodstvo. Moskva. 2001. No. 3, 17-20. Note:  In Russian.
NAL Call Number:  46.8 SV33
Descriptors:  rats as disease vectors, zoonotic disease, pig farms, dead and trapped rats, Brucella, brucellosis, tuberculosis, Mycobacterium, leptospirosis, pest control and eradication.

Barrett, D.C. Biosecurity and herd health -- a challenge for the 21st century. Cattle Practice. 2001. 9 (2) 97-103.
NAL Call Number:  SF961 C37
Descriptors:  animal health, biosecurity, disease transmission, infectious diseases, cattle, poultry, tuberculosis, Mycobacterium bovis, pigs.

Barrett, D.C.; Sibley, R.J.; Taylor, A.J. British cattle veterinary association -- TB isolation and test protocol. Cattle Practice. 2001. 9 (2) 147-150.
NAL Call Number:  SF961 C37
Descriptors:  cattle, diagnosis, disease transmission, isolation, quarantine, reviews, tuberculosis, Mycobacterium bovis.

Barua, A.G.; Singh, N.B.; Barua, C.C.; Raisuddin, S. IL-1beta, TNF and IL-6 mediated activation in murine by Mycobacterium habana, a candidate vaccine strain against tuberculosis.  Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases. 2001. 22 (2) 178-180.
Descriptors:  candidate vaccines, cytokines, immunization, interleukin-6, interleukins, murine macrophages, BALB/c mice, tuberculosis, tumour necrosis factor, cytokine production, vaccination, vaccine development, zoonoses, Mycobacterium tuberculosis, Mycobacterium habana. 

Bellamine, A.; Mangla, A.T.; Dennis, A.L.; Nes, W.D.; Waterman, M.R. Structural requirements for substrate recognition of Mycobacterium tuberculosis 14alpha-demethylase: implications for sterol biosynthesis. Journal of Lipid Research.  Jan 2001. 42 (1) 128-136. ISSN: 0022-2275
NAL Call Number:  381 J8282
Descriptors:  cytochrome p 450, cholesterol, substrates, binding, Mycobacterium tuberculosis.

Beytut, E. Kars Ili ve yoresinde sigirlarda tuberkuloz insidensi ve lezyonlarin lokalizasyonu uzerine patolojik incelemeler. [Pathological examinations on the localization of lesions and incidence of tuberculosis in cattle in Kars City and its surrounding.]  Kafkas Universitesi Veteriner Fakultesi Dergisi. 2001. 7 (1) 15-25. Note:  In Turkish with an English summary.
Descriptors:  disease, incidence, lesion localization, cattle tuberculosis, Mycobacterium, ZN staining, granulomas, lungs, lymph nodes, cattle.

Buddle, B.M.; Ryan, T.J.; Pollock, J.M.; Andersen, P.; de Lisle, G.W. Use of ESAT-6 in the interferon-gamma test for diagnosis of bovine tuberculosis following skin testing. Veterinary Microbiology.  May 3, 2001. 80 (1) 37-46. ISSN: 0378-1135
NAL Call Number:  SF601.V44
Abstract:  The whole blood interferon-gamma (IFN-gamma) test has proven to be a practical ancillary test for re-testing cattle for bovine tuberculosis 8-28 days following tuberculin skin testing. An improvement in the specificity of the IFN-gamma test could further reduce culling of false positive animals. The primary aim of this study was to evaluate a single mycobacterial antigen, ESAT-6 in the IFN-gamma test for use in skin test-positive cattle. These skin test-positive cattle comprised 51 Mycobacterium bovis-infected animals from tuberculosis-infected herds and 85 non-infected animals from tuberculosis-free herds. The test based on ESAT-6 had a higher specificity than the test based on purified protein derivative (PPD) tuberculin, but this was offset by a small decrease in sensitivity. Use of a lower cut-off in the ESAT-6-based test improved the sensitivity, while still maintaining a very high specificity. A secondary aim in the study was to assess the ESAT-6 and PPD-based tests for detecting bovine tuberculosis in skin test-negative animals from a persistently infected herd. The PPD-based test detected the majority of the lesioned or M. bovis-culture positive animals, while the ESAT-6-based test detected a smaller proportion. The false negatives in the IFN-gamma test from both the skin test-negative and positive groups were predominantly M. bovis-culture positive animals with no visible lesions. The current study has shown that a defined specific antigen such as ESAT-6 can markedly improve the specificity of the IFN-gamma test for re-testing skin test-positive animals. An ESAT-6-based IFN-gamma test could be particularly useful to reduce the false positive rate, yet still maintain an acceptable level of sensitivity.
Descriptors:  cows, tuberculosis, interferon, diagnosis, diagnostic skin tests, blood chemistry, tuberculin, culling, antigens, diagnostic techniques, evaluation, Mycobacterium bovis.

Buddle, B.M.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. Vaccination of cattle against Mycobacterium bovis. Tuberculosis. 2001. 81 (1-2) 125-132. Note: Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  Mycobacterium bovis, cattle, vaccination, BCG vaccine, candidate vaccines, vaccine development, disease control and prevention, DNA vaccines, immunization, live vaccines, tuberculosis, reviews.

Caldow, G.; Gunn, G.; Humphry, R.; Crawshaw, M.; Rusbridge, S. Biosecurity and screening for disease.  Irish Veterinary Journal. 2001. 54 (9) 461-470.
NAL Call Number:  41.8 IR4
Descriptors:  diagnostic accuracy, cattle diseases, control programs, diagnostic techniques, disease prevention and control, neosporosis, paratuberculosis, salmonellosis, tuberculosis, Mycobacterium, bovine diarrhea virus, herpesvirus-1, Leptospira.

Cassidy, J.P.; Bryson, D.G.; Cancela, M.M.G.; Forster, F.; Pollock, J.M.; Neill, S.D. Lymphocyte subtypes in experimentally induced early-stage bovine tuberculous lesions.  Journal of Comparative Pathology. 2001. 124 (1) 46-51.
NAL Call Number:  41.8 J82
Descriptors:  lymphocyte subtype identification, bovine tuberculosis, calves, phenotypes, immunohistochemistry, lungs lesions, lymph nodes, T lymphocytes, B lymphocytes, Mycobacterium, cattle, pathogenesis.

Caro, M.R.; Gallego, M.C.; Buendia, A.J.; del Rio, L.; Seva, J.; Navarro, J.A. Differences in lymphocyte subpopulations from peripheral blood and lymphoid organs in natural caprine tuberculosis infection.  Journal of Veterinary Medicine, Series B.  Mar 2001. 48 (2) 81-88. ISSN: 0931-1793
NAL Call Number:  41.8 Z52
Descriptors:  goats, blood, lymph nodes, infections, tuberculosis, defense mechanisms, Mycobacterium tuberculosis, spleen, lesions, cd4+ lymphocytes, cd8 –lymphocytes, B lymphocytes, T lymphocytes, receptors, interleukin 2, rates.

Charleston, B.; Hope, J.C.; Carr, B.V.; Howard, C.J. Masking of two in vitro immunological assays for Mycobacterium bovis (BCG) in calves acutely infected with non-cytopathic bovine viral diarrhoea virus. Veterinary Record. 2001. 149 (16) 481-484. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  calves, BCG vaccination, diagnosis, interferon, lymphocyte transformation, bovine diarrhea virus, Mycobacterium avium, Mycobacterium bovis, pestivirus, in vitro assays.

Chowdhury, J.; Sarkar, S.; Pal, N.K.; Roy, N.; Chakraborty, M. Bovine tuberculosis -- a slaughter house based assessment. Indian Journal of Animal Health. 2001. 40 (1) 41-44.
NAL Call Number:  SF1 I4
Descriptors:  post-slaughter, cattle, prevalence tuberculosis, epidemiology, lung tissue, Mycobacterium bovis, Z-N staining, histological examination by H-E and FFA, test comparison, India, West Bengal.

Coleman, J.D. Possums as vectors of Tb in livestock. Proceedings of the New Zealand Society of Animal Production.  2001. 61:  57-59. Note:  61st Conference, Lincoln University, New Zealand, 25-27 June 2001.
NAL Call Number:  49.9 N483
Descriptors:  animal pathology, disease transmission, disease vectors, epidemiology, lung lesions, cattle, livestock, lymph nodes, tuberculosis, vector control, wild animals, Mycobacterium bovis, Trichosurus vulpecula, brushtail possums, New Zealand.

Cousins, D.V.  Mycobacterium bovis infection and control in domestic livestock. Revue Scientifique et Technique Office International des Epizooties. 2001. 20 (1) 71-85. Note:  In English with French and Spanish summaries.
NAL Call Number:  SF781 R4
Descriptors:
  Mycobacterium bovis, domestic livestock species, disease control and eradication programs, economics, milk pasteurization, tuberculosis.

Cunha, A.P. da; Mota, R.A.; Rabelo,S.S.de A.; Silva, L.B.G.da; Nascimento-Sobrinho, E.S.do; Soares, P.C.; Castro Junior, I.F.de; Bello, A.C.P. de P.  Estudo epidemiologico da infeccao pelo Mycobacterium bovis em bovinos leiteiros do municipio de Gravata-PE.  [An epidemiological survey of Mycobacterium bovis in the municipal district of Gravata, State of Pernambuco, Northeastern Brazil.]  Ciencia Veterinaria nos Tropicos.  2001; 4 (2/3): 291-296.  ISSN:  1415-6326.  Note:  In Portuguese with an English summary.  
Descriptors:  different breeds of cattle, Mycobacterium bovis, 20 dairy herds, epidemiological surveys, diagnosis, double comparative testing, purified protein derivative—mammalian and avian, 40% of herds showed positive skin reaction, Gravata region, Brazil.

Cvetnic, Z.; Spicic, S. Rasprostranjenost tuberkuloze svinja u Republici Hrvatskoj u razdoblju od 1990. do 2000. godine. [Expansion of tuberculosis in pigs in the Republic of Croatia in the period 1990-2000.]  Praxis Veterinaria Zagreb. 2001. 49 (3) 113-116. Note:  In Croatian with an English summary.
Descriptors:  disease prevalence, disease surveys, epidemiology, seroprevalence, tuberculosis, Mycobacterium, pigs, 17 breeding farms, tuberculin test, Croatia.

de Lisle, G.W.  Bovine tuberculosis: a view from down under. Veterinary Journal.  May 2001. 161 (3) 220-221. ISSN: 1090-0233
URL:
http://intl.elsevierhealth.com/journals/tvjl/
NAL Call Number:  SF601.V484
Descriptors:  cattle, Mycobacterium bovis, deer, badgers, disease control programs, tuberculosis disease control, UK, New Zealand.

Delahay, R.J.; Cheeseman, C.L.; Clifton-Hadley, R.S.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. Wildlife disease reservoirs: the epidemiology of Mycobacterium bovis infection in the European badger (Meles meles) and other British mammals. Tuberculosis. 2001. 81 (1-2) 43-49. Note: Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  animal behavior, disease distribution, disease prevalence, disease transmission, epidemiology, reservoir hosts, wildlife, cats, deer, cattle, foxes, ferrets, badgers, mink, rats, Rattus norvegicus, Talpa europaea, Great Britain, New Zealand.

Di Falco, A.; Piancone, G.; Balla, S.; Defilippi, A. Presenza di isoniazide nel latte piemontese.  [Isonicotinic acid hydrazide in milk of Piedmont region.] Industrie Alimentari. 2001. 40 (405) 755-758. Note:  In Italian with an English summary.
NAL Call Number:  HD9000.1 I52
Descriptors:  cattle, cattle farming, drug residues in milk, isoniazid, Italy.

Enticott, G. Calculating nature: the case of badgers, bovine tuberculosis and cattle. Journal of Rural Sudies.  Apr 2001. 17 (2) 149-164. ISSN: 0743-0167
NAL Call Number:  HT401.J68
Abstract:  The aim of the paper is to examine the governmentalities associated with attempts to manage nature. In particular, it assesses the role that numbers have played in rural governance. Numbers are seen as an important tool of modern government. However, like other aspects of science, their use in governing nature has been contested by other epistemologies. Drawing upon efforts to regulate the spread of bovine tuberculosis in cattle, the paper firstly examines how numbers have been used in this policy debate. Secondly, the paper outlines three epistemologies of nature--nature as numbers, nature as known and ecological nature--which have been employed in contesting government policy. Finally the paper concludes by analysing the interactions of these knowledges of nature and considering the voice of the badger in these constructions of its identity.
Descriptors:  badgers, dairy cattle, Mycobacterium tuberculosis, disease control, disease transmission, Ministries of Agriculture, government policy, rural areas, farmers' attitudes, UK.

Estrada-Chavez, C.; Mancilla, R.; Arriaga-Diaz, C.; Perez-Gonzalez, R.; Diaz-Otero, F. Determinacion de anticuerpos anti-PPD en hatos lecheros con distintas prevalencias de tuberculosis bovina en Mexico. [Antibody response to PPD in cattle from herds with different tuberculosis prevalence in Mexico.] Veterinaria Mexico. 2001. 32 (3) 207-211. Note:  In Spanish with an English summary.
NAL Call Number:  SF604 V485
Descriptors:  antibody response to PPD, serum samples, disease eradification, diagnosis, ELISA, epidemiology, herds, immune response, tuberculin, tuberculosis in cattle, Mycobacterium bovis, Mexico.

Estrada-Chavez, C.; Pereira-Suarez, A.L.; Meraz, M.A.; Arriaga, C.; Garcia-Carranca, A.; Sanchez-Rodriguez, C.; Mancilla, R. High-level expression of NRAMP1 in peripheral blood cells and tuberculous granulomas from Mycobacterium bovis-infected bovines. Infection and Immunity.  Nov 2001. 69 (11) 7165-7168. ISSN: 0019-9567
NAL Call Number:  QR1.I57
Abstract:  By Western blotting, we demonstrate high-level expression of NRAMP1 proteins in peripheral blood cells and granulomas of Mycobacterium bovis-infected bovines. Immunohistochemistry of granulomatous lesions showed heavily labeled epithelioid macrophages and Langhans cells. These data suggest that M. bovis infection enhances NRAMP1 expression and that active tuberculosis can occur despite this response.
Descriptors:  tubercular lesions, disease impact on NRAMP1 expression, Mycobacterium bovis.

Fujikura, T.  Present situation and problems in farm animal production in the Dominican Republic.  Journal of Veterinary Medicine, Japan. 2001. 54 (2) 104-111. Note:  In Japanese.
Descriptors:  animal diseases, disease prevalence, tuberculosis, Mycobacterium, Brucella, brucellosis, cattle, Dominican Republic.

Goodchild, A.V.; Clifton-Hadley, R.S.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. Cattle-to-cattle transmission of Mycobacterium bovis.  Tuberculosis. 2001. 81 (1-2) 23-41. Note:  Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  cattle, Mycobacterium bovis, Mycobacterium tuberculosis, disease control and transmission.

Grossklaus, D. Zoonosenbekampfung -- Neue Herausforderungen beim gesundheitlichen Verbraucherschutz. [Zoonoses control -- new challenges in health protection of consumers.] Berliner und  Munchener Tierarztliche Wochenschrift. 2001. 114 (11-12) 420-427. Note:  In German with an English summary.
NAL Call Number:  41.8 B45
Descriptors:  brucellosis, Brucella, tuberculosis, Mycobacterium, consumer protection, zoonotic diseases, control programs, disease control, surveys, EU regulations, foodborne diseases, latent infections, livestock, monitoring, public health, Salmonella, zoonoses, Germany.

Guarino, A.; di Sarno, A.; Palazzo, M.A.; Fusco, G.; Pompei, G.; Vendemia, N.; Fenizia, D. Mycobacterium bovis infection in water buffalo (Bubalus bubalis) in Italy. Buffalo Journal. 2001. 17 (3) 417-423.
Descriptors:  biochemistry, contamination, epidemiology, histopathology, lesions, lymph nodes, oedema, tuberculin, tuberculosis, zoonoses, buffalo, Bubalus bubalis, Mycobacterium bovis, Campania, Italy.

Hancox, M.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. Cattle TB schemes: control or eradication: a critical reappraisal. Tuberculosis. 2001. 81 (1-2) 185-187. Note:  Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  cattle, disease prevention and contol, disease eradication and transmission, epidemiology, Mycobacterium bovis, diseases, pathogenesis.

Kazwala, R.R.; Kambarage, D.M.; Daborn, C.J.; Nyange, J.; Jiwa, S.F.H.; Sharp, J.M. Risk factors associated with the occurrence of bovine tuberculosis in cattle in the southern highlands of Tanzania. Veterinary Research Communications. Dec 2001. 25 (8) 609-614. ISSN: 0165-7380
NAL Call Number:  SF601.V38
Descriptors:  cattle, Mycobacterium bovis infections, detection, diagnosis, risk factors, incidence, disease prevalence, climatic factors, age differences, male animals, female animals, blood chemistry, breed differences, steers, pregnancy, lactation, geographical variation, Tanzania.

Kim, YongHwan; Al-Haddawi, M.H.; Cho, HoSeong, Kang, SungKwi; Cho, KyoungOh; Park, HyungSeon; Lee, BongJoo; Park, NamYong.  Multiplex PCR for differential diagnosis of Mycobacterium species from bovine clinical samples.  Korean Journal of Veterinary Research. 2001. 41 (4) 535-542. Note:  In Korean with an English summary.
NAL Call Number:  41.9 T12
Descritpors:  multiplex PCR technique, early detection method, Mycobacterium bovis, Mycobacterium tuberculosis, Mycobacterium avium, Mycobacterium avium subsp. paratuberculosis, clinical samples, field cattle, ITT assay, comparison study, skin tests.

Kita J.; Mazurek, J. Zagrozenia zdrowotne chorobami odzwierzecymi przeniesionymi przez zwierzeta lub material pochodzenia zwierzecego. [Health risks originating in animal diseases acquired directly or via animal products.] Przeglad Epidemiologiczny. 2001. 55 (Suppl. 2) 213-216. Ogolnopolska konferencja naukowa "Nowopojawiajace sie nawracajace i bioterrorystyczne zagrozenia ze strony zakaznych chorob odzwierzecych", Warszawa, Polska, 2001. Note: From a conference proceeding published in Polish.
NAL Call Number:  RA651 P7
Descriptors:  veterinary regulations, international trade, quarantine, various diseases, Q fever, immunodeficiency, legionnaires disease, Lyme disease, Ebola, influenza and encephalopathies, tuberculosis, Mycobacterium, enzootic leukaemia, brucellosis, IBR, paratuberculosis, leptospirosis.

Kohler, H.; Gyra, H.; Zimmer, K.; Drager, K.G.; Burkert, B.; Lemser, B.; Hausleithner, D.; Cussler, K.; Klawonn, W.; Hess, R.G. Immune reactions in cattle after immunization with a Mycobacterium paratuberculosis vaccine and implications for the diagnosis of M. paratuberculosis and M. bovis infections.  Journal of Veterinary Medicine. Series B. 2001. 48 (3) 185-195.
NAL Call Number:  41.8 Z52
Descriptors:  immune response, antibodies, calves, cattle, cell mediated immunity, diagnosis, humoral immunity, immunization, live vaccines, tuberculin, vaccination, Mycobacterium avium ssp. paratuberculosis, Mycobacterium bovis.

Lavender, A.; Mitchell, T.; UK, Department for Environment, Food & Rural Affairs. Animal Health 2001 – Report of the Chief Veterinary Officer. 2001. 94 pp. Department of Environment, Food and Rural Affairs (DEFRA), London, UK.
Descriptors:  animal health, animal welfare, bovine spongiform encephalopathy, consumer protection, control programs, disease control, disease prevention, disease surveys, disease transmission, food safety, foot and mouth disease, government organizations, international trade, livestock monitoring, outbreaks, public health, reports, trade in animals, transport of animals, tuberculosis, zoonoses, cattle, Mycobacterium tuberculosis, TSE, UK.

Lilenbaum, W.; Pessolani, M.C.V.; Fonseca, L.S. The use of Ag85 complex as antigen in ELISA for the diagnosis of bovine tuberculosis in dairy cows in Brazil. Journal of Veterinary Medicine, Series B.  Apr 2001. 48 (3) 161-166. ISSN: 0931-1793
NAL Call Number:  41.8 Z52
Descriptors:  dairy cows, antigens, tuberculosis, immunodiagnosis, evaluation, ELISA, performance, antibodies, infections, Mycobacterium bovis, Brazil.

Livingstone, P.G. Advances in the diagnosis, control and eradication of bovine tuberculosis (Mycobacterium bovis) in domestic and wild animals.  68th General Session of the International Committee, Paris, 22-26 May 2000. Comprehensive reports on technical items presented to the International Committee or to Regional Commissions, 2000. Office International des Epizooties; Paris; France 2001. p 103-123. Note:  In English, French, Spanish, and Russian.
Descriptors:  cattle diseases, control programs, diagnosis and disease control, epidemiology, immunological techniques, tuberculosis, vaccination, wild animals, deer, Mycobacterium.

Lofgren, S. Studies of prevalence, pathology, isolation and characterisation of bovine tuberculosis in Lusaka, Zambia. Minor Field Studies. International Office, Swedish University of Agricultural Sciences. Uppsala; Sweden 2001. No. 152, 28 pp.
Descriptors:  characterization, disease prevalence, epidemiology, food hygiene, foodborne diseases, lesions, meat inspection, tuberculosis, zoonoses, Mycobacterium tuberculosis, cattle, Zambia.

Magnano, G.; Sorribes, A.; Schneider, M.; Giraudo, J.; Bergamo, E.; Navarro, F. Tuberculosis bovinal una experiencia de saneamiento en tambo. [Bovine tuberculosis: a sanitary experience in dairy farm.Veterinaria Argentina. 2001. 18 (180) 732-745. Note:  In Spanish with an English summary.
NAL Call Number:  SF604 V463
Descriptors:  dairy cattle, disease prevalence, prevention and control, epidemiology, Mycobacterial bovis, diseases, sanitation, tuberculin skin tests, tuberculosis, Argentina.

Menzies, F.D.; Neill, S.D.  Bovine tuberculosis: controlling cattle-to-cattle transmission. Cattle Practice. 2001. 9 (4) 243-247.
NAL Call Number:  SF961 C37
Descriptors:  diagnosis, disease control, disease prevention, disease transmission, tuberculosis, cattle, Mycobacterium bovis.

Miao, Z.H.; Glatz, P.C.; English, A.; Ru,Y.J. Managing fallow deer (Dama dama) and red deer (Cervus elaphus) for animal house research. ANZCCART News. 2001. 14 (4) Insert 1-Insert 8.
NAL Call Number:  SF405.5 A3
Descriptors:  animal behavior, housing, nutrition, production systems, fallow and red deer farming, Dama dama, Cervus elaphus, ectoparasites, bacterial diseases, protozoal diseases, viral infection, Australia.

Miciora, R. Aspecte epidemiologice ale infectiei cu Mycobacterium bovis la animale si om. [Epidemiological aspects of Mycobacterium bovis infection in animals and man.]  Revista Romana de Medicina Veterinara. 2001. 11 (1) 19-32. Note:  In Romanian.
NAL Call Number:  SF604 R48
Descriptors:  badgers, cattle, Mycobacterium bovis, zoonotic diseases, disease reservoir, clinical aspects, disease transmission, epidemiology, tuberculosis, reviews.

Monreal, L.; Segura, D.; Segales, J.; Garrido, J.M.; Prades, M. Diagnosis of Mycobacterium bovis infection in a mare. Veterinary Record.  Dec 8, 2001. 149 (23) 712-714. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  mares, horses, Mycobacterium bovis, tuberculosis, diagnosis, polymerase chain reaction, spleen, lesions, case reports.

Neill, S.D.; Bryson, D.G.; Pollock, J.M.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. Pathogenesis of tuberculosis in cattle. Tuberculosis. 2001. 81 (1-2) 79-86. Note:  Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  disease models, experimental infections, immune response, pathogenesis, cattle tuberculosis, Mycobacterium, review.

Nugent, G. Deer and pigs as hosts of bovine tuberculosis, and their potential use as sentinels of disease presence. Proceedings of the New Zealand Society of Animal Production. 2001. 61: 64-67. Note:  61st conference, Lincoln University, New Zealand, 25-27 June 2001.
NAL Call Number:  49.9 N483
Descriptors:  disease prevalence, hosts, sentinel animals, tuberculosis, wild animals, wild pigs, cattle, Cervus elaphus, deer, Mycobacterium bovis, pigs, red deer, Trichosurus vulpecula, New Zealand.

Omer, M.K.; Skjerve, E.; Woldehiwet, Z.; Holstad, G.  A cross-sectional study of bovine tuberculosis in dairy farms in Asmara, Eritrea.  Tropical Animal Health and Production.  July 2001. 33 (4) 295-303. ISSN: 0049-4747. Note:  In English with a Spanish and French summary.
NAL Call Number:  SF601.T7
Descriptors:  dairy cattle, bovine tuberculosis, Mycobacterium bovis, dairy farms, disease prevalence, risk factors, diagnosis, mathematical models, dairy breeds, risk assessment, livestock numbers, epidemiology, cattle housing, intradermal tuberculin test, herd survey, prevalence, risk of disease, Eritrea.

Orme, I.M.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. Immunology and vaccinology of tuberculosis: can lessons from the mouse be applied to the cow? Tuberculosis. 2001. 81 (1-2) 109-113. Note:  Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  CD4+ lymphocytes, cows, cattle, mice, disease models, laboratory animals, experimental infections, host resistance, immunity, immunology, interferon, lungs, tuberculosis, vaccine development, vaccines, Mycobacterium tuberculosis.

Patel, R.M.; Joshi, C.G.; Solanki, J.V.; Patel, P.R.  PCR based detection of tuberculosis from blood using oligo primers in cattle. Indian Veterinary Journal. 2001. 78 (6) 480-482.
NAL Call Number:  41.8 IN2
Descriptors:  blood, dairy cattle, Mycobacterium bovis, diagnosis, diagnostic techniques, DNA, tuberculin test, feces, PCR, India.

Pfeiffer D.U. TB: current status and control: a view from the outside. Cattle Practice. 2001. 9 (4) 249-255.
NAL Call Number:  SF961 C37
Descriptors:  disease control and transmission, epidemiology, reservoir hosts, tuberculosis in cattle, Mycobacterium bovis, UK.

Pollock, J.M.; McNair, J.; Welsh, M.D.; Girvin, R.M.; Kennedy, H.E.; Mackie, D.P.; Neill, S.D.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. Immune responses in bovine tuberculosis. Tuberculosis. 2001. 81 (1-2) 103-107. Note:  Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  antigens, cell mediated immunity, immune response, macrophages, disease control, Mycobacterium bovis, disease models, cattle, experimental infections, T lymphocyes, tuberculosis,  macrophages, reviews.

Pollock, J.M.; Buddle, B.M.; Andersen, P.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. Towards more accurate diagnosis of bovine tuberculosis using defined antigens. Tuberculosis. 2001. 81 (1-2) 65-69. Note: Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  cattle, Mycobacterium bovis, Mycobacterium tuberculosis, abattoirs, antigens, diagnosis, diagnostic techniques, immune response, reviews.

Quirin, R.; Rasolofo, V.; Andriambololona, R.; Ramboasolo, A.; Rasolonavalona, T.; Raharisolo. C.; Rakotoaritahina, H.; Chanteau, S.; Boisier, P. Validity of intradermal tuberculin testing for the screening of bovine tuberculosis in Madagascar. Onderstepoort Journal of Veterinary Research. 2001. 68 (3) 231-238.
NAL Call Number:  41.8 On1
Descriptors:  cattle, prevalence survey, intrademal tuberculin test, epidemiology, test validity, sensitivity and specificity, preslaughter, Mycobacterium bovis, Madagascar.

Reis, D.O.; de Almeida, L.P.; Pimenta, A.; Vieira, R.L. Zoonoses reemergentes: um estudo com bovinos abatidos em frigorifico da regiao Sudeste do Brasil. [Reemerging zoonoses: a study of cattle slaughtered in the south eastern region of Brazil.] Higiene Alimentar. 2001. 15 (82) 23-26. Note:  In Portuguese with an English summary.
Descriptors:  post-slaughter survey, cattle, 1984-98, 317372, 0.08% positive for tuberculosis, Mycobacterium, bursitis, Minas Gerais, Brazil.

Rhodes, S.G.; Hewinson, R.G.; Vordermeier, H.M. Antigen recognition and immunomodulation by gammadelta T cells in bovine tuberculosis. Journal of Immunology. 2001. 166 (9) 5604-5610.
NAL Call Number: 448.8 J8232
Descriptors:  antigens, experimental infection, in vitro, interferon, lymphocyte transformation, T lymphocytes, cattle tuberculosis, cattle, Mycobacterium bovis, gammadelta, T cells, immunomodulation.

Silva, E. Evaluation of an enzyme-linked immunosorbent assay in the diagnosis of bovine tuberculosis.  Veterinary Microbiology. Jan 26, 2001. 78 (2) 111-117. ISSN: 0378-1135
NAL Call Number:  SF601.V44
Descriptors:  cattle, Mycobacterium bovis, ELISA, diagnosis, evaluation, lesions, disease prevalence, diagnostic techniques, sensitivity, bovine tuberculosis, histopathology.

Silva, E.; Merlini, J.C.; de Kantor, I.N.; Robinson, A.; Aluffi, L.; Martinez, N.; Moscatelli, J. Evaluacion de campo del sistema DAVIH TBB en el diagnostico serologico de la tuberculosis bovina en Argentina. [Field evaluation of DAVIH TBB system in the serological diagnosis of bovine tuberculosis in Argentina.] Revista de Salud Animal. 2001. 23 (3) 165-168. Note:  In Spanish with an English summary.
NAL Call Number:  SF1 R484
Descriptors:  antibodies, diagnosis, diagnostic techniques, disease distribution, disease prevalence, ELISA, epidemiology, immunodiagnosis, skin tuberculin testing, tuberculosis in cattle, Mycobacterium bovis, Argentina.

Smith, G.C.; Cheeseman, C.L.; Wilkinson, D.; Clifton Hadley, R.S. A model of bovine tuberculosis in the badger Meles meles: the inclusion of cattle and the use of a live test. Journal of Applied Ecology.  June 2001. 38 (3) 520-535. ISSN: 0021-8901
NAL Call Number:  410 J828
Descriptors:  tuberculosis, Mycobacterium bovis, cattle, badgers, Meles meles, infection, disease control, disease transmission, culling, ELISA, stochastic models, simulation models, population dynamics, epidemiology, vectorial capacity, disease prevalence, England.

Smith, G.C.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. Models of Mycobacterium bovis in wildlife and cattle. Tuberculosis. 2001. 81 (1-2) 51-64. Note:  Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  badgers, cattle, deer, Didelphidae, Mycobacterium bovis, Mycobacterium tuberculosis, disease control, disease models, reviews, simulation models, wild animals, small mammals.

Smith, R.A.; Alvarez, A.J.; Estes, D.M. The P2X7 purinergic receptor on bovine macrophages mediates mycobacterial death. Veterinary Immunology and Immunopathology.  Feb 10, 2001. 78 (3/4) 249-262. ISSN: 0165-2427
NAL Call Number:  SF757.2.V38
Abstract:  P2X7 is an ATP gated purinoceptor that has been linked to various immune responses. P2X7 appears to be expressed ubiquitously in the immune system and thus may be important as an effector pathway or play significant roles in cell activation/death. 2',3'-(4-Benzoyl)benzoyl ATP is the most potent agonist of this receptor and ATP in its fully dissociated form (ATP(4-)) also activates the receptor. High concentrations of ATP can cause the P2X7 receptor to induce pore formation on the surface of the cell that allows molecules of considerable size to pass and can lead to cell death. The P2X7 receptor has also been linked to various immune activities when the concentration of ATP is lower, including the release of IL-1beta. The role P2X7 receptors have on immune cell activities is just beginning to be understood. We sought to determine the role of P2X7 on bovine macrophages in eliminating the causative agent of bovine-type tuberculosis, Mycobacterium bovis. Because high concentrations of ATP are linked to macrophage death, we determined if this method of cell destruction also leads to reduced bacterial viability. We find that P2X7 is present on bovine macrophages from different sources, including both peripheral blood-derived as well as alveolar macrophages. In addition, P2X7 mRNA is present in B and T lymphocytes. The treatment of M. bovis-infected macrophages with ATP results in reduced macrophage viability as well as reduced M. bovis viability.
Descriptors:  cattle, macrophages, Mycobacterium bovis BCG strain, receptors, messenger RNA, viability, death, cell growth, ATP, B lymphocytes, T lymphocytes.

Smyth, A.J.; Welsh, M.D.; Girvin, R.M.; Pollock, J.M.  In vitro responsiveness of gamma delta T cells from Mycobacterium bovis-infected cattle to mycobacterial antigens: predominant involvement of WC1+ cells.  Infection and Immunity.  2001; 69 (1): 89-96.  ISSN: 0019-9567
URL: http://iai.asm.org/
NAL Call Number:  QR1.I57
Abstract:  It is generally accepted that protective immunity against tuberculosis is generated through the cell-mediated immune (CMI) system, and a greater understanding of such responses is required if better vaccines and diagnostic tests are to be developed.  Gammadelta T cells from a major proportion of the peripheral blood mononuclear cells (PBMC) in the ruminant system and, considering data from other species, may have a significant role in CMI responses in bovine tuberculosis.  This study compared the in vitro responses of alphabeta and gammadelta T cells from Mycobacterium bovis-infected and uninfected cattle.  The results showed that, following 24 h of culture of PBMC with M. bovis-derived antigens, the majority of gammadelta T cells from infected animals became highly activated (upregulation of interleukin-2R), while a lower proportion of the alphabetaT-cell population showed activation.  Similar responses were evident to a lesser degree in uninfected animals.  Study of the kinetics of this response showed that gammadelta T cells remained significantly activated for at least 7 days in culture, while activation of alphabeta T cells declined during that period.  Subsequent analysis revealed that the majority of activated gammadelta T cells expressed WC1, a 215-kDa surface molecule which is not expressed on human or murine gammadelta T cells.  Furthermore, in comparison with what was found for CD4+ T cells, M. bovis antigen was found to induce strong cellular proliferation but relatively little gamma interferon release by purified WC1+ gammadelta T cells.  Overall, while the role of these cells in protective immunity remains unclear, their highly activated status in. response to M. bovis suggests an important role in antimycobacterial immunity, and the ability of gammadelta T cells to influence other immune cell functions remains to be elucidated, particularly in relation to CMI-based diagnostic tests.
Descriptors:  T lymphocytes, cell mediated immunity, bacterial antigens.  

Skinner, M.A.; Wedlock, D.N.; Buddle, B.M. Vaccination of animals against Mycobacterium bovis.  Revue Scientifique et Technique Office International des Epizooties. 2001. 20 (1) 112-132. Note:  In English with French and Spanish summaries.
NAL Call Number:  SF781 R4
Descriptors:  disease control, immune response, immunology, recombinant vaccines, tuberculosis, vaccination, wildlife, cattle, deer, Mycobacterium bovis.

Taylor, M.J.; Hughes, M.S.; Skuce, R.A.; Neill, S.D. Detection of Mycobacterium bovis in bovine clinical specimens using real-time fluorescence and fluorenscence resonance energy transfer probe rapid-cycle PCR.  Journal of Clinical Microbiology. Apr 2001. 39 (4) 1272-1278. ISSN: 0095-1137
NAL Call Number:  QR46.J6
Descriptors:  cattle, tuberculosis, polymerase chain reaction, PCR, lymph nodes.

Thorel, M.F.; Huchzermeyer, H.F.; Michel, A.L.  Mycobacterium avium and Mycobacterium intracellulare infection in mammals. Revue Scientifique et Technique Office International des Epizooties. 2001. 20 (1) 204-218. Note:  In English with French and Spanish summaries.
NAL Call Number:  SF781 R4
Descriptors:  domestic animals, immunosuppression, post slaughter survey, soil microbes, tuberculosis, water, cats, dogs, small mammals, wild animals, wild birds, zoonotic diseases.

Valsson, O.; Alenius, S.; Nielsen, T.K.; Nyberg, O.; Salmela, P.; Elvander, M. (ed.); Lindberg, A. (ed.); Christensen, B. Surveillance of ruminant diseases in the Nordic countries. Acta Veterinaria Scandinavica, Supplementum. 2001. No. 94 supp. 27-28. Proceedings of the 13th Nordic Committee for Veterinary Scientific Cooperation (NKVet) Symposium on National Disease Control in Farmed Animals, Stockholm, Sweden, 1-2 October 1999.
NAL Call Number:  41.8 Ac87 Suppl.
Descriptors:  animal health; cattle diseases, bovine leucosis, brucellosis, BSE, paratuberculosis, scrapie, tuberculosis, salmonellosis, Mycobacterium, prevention and control, surveillance.

Vordermeier, H.M.; Cockle, P.J.; Whelan, A.O.; Rhodes, S.; Chambers, M.A.; Clifford, D.; Huygen, K.; Tascon, R.; Lowrie, D.; Colston, M.J.; Hewinson, R.G. Effective DNA vaccination of cattle with the mycobacterial antigens MPB83 and MPB70 does not compromise the specificity of the comparative intradermal tuberculin skin test. Vaccine. 2001. 19 (9-10) 1246-1255.
NAL Call Number:  QR189 V32
Descriptors:  bovine tuberculosis, control and prevention, tuberculin test, culling strategy, DNA vaccine development, mycobacterial antigens, MPB70, MPB83, Ag85A, calves, cellular immune responses, CD4+ T cells, effectiveness, cattle, Mycobacterium bovis, South West England.

Vordermeier, M.; Aranaz, A.; Pollock, J.M.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. Immunodiagnosis of bovine tuberculosis. Summary of a satellite workshop of the Mycobacterium bovis 2000 conference, Cambridge, UK, 17 August 2000. Tuberculosis. 2001. 81 (1-2) 177-180. Note:  Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:
  Mycobacterium bovis, cattle, antigens, concurrent infections, detection, diagnosis, disease control, immunization, immunodiagnosis, immunological techniques, interferon, mycobacterial diseases, serology, tuberculin, tuberculosis, vaccination.

Vordermeier, H.M.; Whelan, A.; Cockle, P.J.; Farrant, L.; Palmer, N.; Hewinson, R.G. Use of synthetic peptides derived from the antigens ESAT-6 and CFP-10 for differential diagnosis of bovine tuberculosis in cattle. Clinical and Diagnostic Laboratory Immunology. 2001. 8 (3) 571-578; 57.
Descriptors:  cattle, antigens, BCG vaccine, differential diagnosis, immunization, vaccination, vaccine development, Mycobacterium bovis, UK.

Vural, S.A.; Tunca, R. Generalized tuberculosis in a 45 day-old calf. Deutsche Tierarztliche Wochenschrift. 2001. 108 (11) 468-470. Note:  In English with a German summary.
NAL Call Number:  41.8 D482
Descriptors:  bacterial antigens, calves, case reports, histopathology, immunohistochemistry, lesions, liver, lungs, lymph nodes, macrophages, tuberculosis, cattle, Mycobacterium bovis.

Whipple, D.L.; Palmer, M.V.; Slaughter, R.E.; Jones, S.L. Comparison of purified protein derivatives and effect of skin testing on results of a commercial gamma interferon assay for diagnosis of tuberculosis in cattle.  Journal of Veterinary Diagnostic Investigation.  Mar 2001. 13 (2) 117-122. ISSN: 1040-6387
NAL Call Number:  SF774 J68
Descriptors:  cattle, tuberculosis, Mycobacterium bovis, interferon assay, skin tests, blood, stimulation, bacterial antigens, bacterial proteins, diagnosis.

Wood, P.R.; Jones, S.L.; Ellner, J.J. (ed.); Brennan, P.J. (ed.); Young, D. BOVIGAMTM: an in vitro cellular diagnostic test for bovine tuberculosis.  Tuberculosis. 2001. 81 (1-2) 147-155. Note:  Third international conference on Mycobacterium bovis, M. bovis 2000, Cambridge, UK, 13-16 August, 2000.
Descriptors:  diagnostic tests and techniques, assays, in vitro testing, alternative to animal testing, BCG vaccine, dexamethasone, diagnosis, drug therapy, Mycobacterium bovis, immunization, interferon, parturition, skin tests, T lymphocytes, bovine tuberculosis, vaccination, cattle, reviews.

Zanini, M.S.; Moreira, E.C.; Lopes, M.T.P.; Oliveira, R.S.; Leao, S.C.; Fioravanti, R.L.; Roxo, E.; Zumarraga, M.; Romano, M.I.; Cataldi, A.; Salas, C.E. Mycobacterium bovis: polymerase chain reaction identification in bovine lymphonode biopsies and genotyping in isolates from Southeast Brazil by spolygotyping and restriction fragment length polymorphism. Memorias do Instituto Oswaldo Cruz. 2001. 96 (6) 809-813.
NAL Call Number:  448.9 IN74
Descriptors:  diagnostic techniques, genotypes, lymph nodes, polymerase chain reaction, polymorphism, cattle, Mycobacterium bovis.

2000

Abernethy, D.A.; Pfeiffer, D.U.; Neill, S.D. Case control study examining the role of livestock markets in the transmission of bovine tuberculosis.  Proceedings of a Meeting, Society for Veterinary Epidemiology and Preventive Medicine [Great Britain].  2000. p. 108-114. ISSN: 0956-7496. Note:  Meeting held on Mar 29-31, 2000, Edinburgh.
NAL Call Number:  SF780.9.S63
Descriptors:  cattle, Mycobacterium bovis, disease transmission, livestock markets, disease prevention and control, epidemiology, cattle, badgers, UK.

Acosta, B.; Real, F.; Leon, L.; Deniz, S.; Ferrer, O.; Rosario, I.; Ramirez, A. ELISA for anti-MPB70: an option for the diagnosis of goat tuberculosis caused by Mycobacterium bovis. Australian Veterinary Journal.  June 2000. 78 (6) 423-424. ISSN: 0005-0423
NAL Call Number:  41.8 Au72
Descriptors:  goats, tuberculosis, Mycobacterium bovis, ELISA, skin tests, Corynebacterium pseudotuberculosis, Mycobacterium paratuberculosis, diagnostic value.

Aldwell, F.E.; Dicker, B.L.; da S. Tatley, F.M.; Cross, M.F.; Liggett, S.; Mackintosh, C.G.; Griffin, J.F.T. Mycobacterium bovis-infected cervine alveolar macrophages secrete lymphoreactive lipid antigens. Infection and Immunity. 2000. 68 (12) 7003-7009.
NAL Call Number:  QR1.I57
Abstract:  Tuberculosis is caused by intracellular bacteria belonging to the genus Mycobacterium, including M. tuberculosis and M. bovis. Alveolar macrophages (AMs) are the primary host cell for inhaled mycobacteria. However, little is known about the mechanisms by which infected AMs can process and present mycobacterial antigens to primed lymphocytes and how these responses may affect ensuing protection in the host. In the present study, we sought to determine whether AMs from a naturally susceptible host for M. bovis (red deer) could produce and secrete soluble immunoreactive antigens following mycobacterial infection in vitro. Confluent monolayers of deer AMs were infected with either heat-killed or live virulent M. bovis or M. bovis BCG at a multiplicity of infection of 5:1 and cultured for 48 h. Culture supernatants were collected, concentrated, and tested for the presence of mycobacterial antigens in a lymphocyte proliferation assay by using peripheral blood mononuclear cells from M. bovis-sensitized or naive deer. Supernatants derived from macrophages which had been infected with live bacilli stimulated the proliferation of antigen-sensitized, but not naive, lymphocytes. Supernatants derived from uninoculated AMs or AMs inoculated with heat-killed bacilli failed to stimulate lymphocyte proliferation. The lymphoproliferative activity was retained following lipid extraction of the supernatants, which were free of amino groups as determined by thin-layer chromatography. These results demonstrate that mycobacteria which are actively growing within AMs produce lipids which are secreted into the extracellular milieu and that these lipids are recognized by lymphocytes from mycobacterium-primed hosts. We suggest that mycobacterial lipids are released from AMs following aerosol infection in vivo and that they play an important role in the early immune response to tuberculosis.
Descriptors:  deer, Mycobacterium bovis, bacterial antigens, lipid secretions, lymphocyte transformation, lymphocytes, macrophages, lymphoproliferative activity, alveolar macrophages.

Ameni, G.; Miorner, H.; Roger, F.; Tibbo, M. Comparison between comparative tuberculin and gamma-interferon tests for the diagnosis of bovine tuberculosis in Ethiopia. Tropical Animal Health and Production. Oct 2000. 32 (5) 267-276. ISSN: 0049-4747. Note:  Summaries in French and Spanish.
NAL Call Number:  SF601.T7
Descriptors:  zebu  cattle, tuberculosis, Mycobacterium bovis, skin tests, diagnostic value, interferon, tuberculin, delayed type hypersensitivity, blood plasma, false negative results, Ethiopia.

Ameni, G.; Medhin, G. Effect of gastro-intestinal parasitosis on tuberculin test for the diagnosis of bovine tuberculosis. Journal of Applied Animal Research. 2000. 18 (2) 221-224. Note:  In English with a Hindi summary.
NAL Call Number:  SF55 I4J68
Descriptors:  gastrointestinal diseases, parasitoses, immune response, tuberculin testing, Mycobacterium, bovine tuberculosis, Fasciola, Paramphistomum, Schistosoma, coccidian, flukes, cattle.

Anonomyous. Bovine TB: working towards a long-term solution. Veterinary Record.  Feb 19, 2000. 146 (8) 201-202. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, tuberculosis, reports, epidemiology, disease control, UK.

Anonomyous.  TB and animal husbandry. Veterinary Record.  May 27, 2000. 146 (22) 621. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  tuberculosis, cattle, cattle husbandry, Mycobacterium bovis, disease transmission.

Antognoli, M.C.; Hernandez, J.A.; Triantis, J.; Salman, M.D.  The use of One tube Nested (OTN) PCR for the detection of Mycobacterium bovis in milk from naturally TB-infected herds: the association between tuberculin test reactions and the presence of M. bovis in milk.  Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: ld 572.
Descriptors:  cattle, Mycobacterium bovis, PCR, zoonotic infections, Mexico.

Asseged, B.; Lubke-Becker, A.; Lemma, E.; Taddele, K.; Britton, S. Bovine tuberculosis: a cross sectional and epidemiological study in and around Addis Ababa. Bulletin of Animal Health and Production in Africa. 2000. 48 (2) 71-80. Note:  Includes a French summary.
NAL Call Number:  41.8 B872
Descriptors:  tuberculin testing, disease incidence, bovine tuberculosis, cattle, intradermal cervical testing, epidemiology, milk, nasal swabs, Mycobacterium bovis, Ethiopia.

Barlow, N.D. Non-linear transmission and simple models for bovine tuberculosis. Journal of Animal Ecology. 2000. 69 (4) 703-713.
NAL Call Number:  410 J826
Descriptors:  mathematical models, disease transmission, tuberculosis, wild animals, epidemiology, cattle diseases, brushtail possum, Trichosurus vulpecula, cattle, Mycobacterium bovis, New Zealand.

Barthel, R.; Piedrahita, J.A.; McMurray, D.N.; Payeur, J.; Baca, D.; Guemes, F.S.; Perumaalla, V.S.; Ficht, T.A.; Templeton, J.W.; Adams, L.G. Pathologic findings and association of Mycobacterium bovis infection with the bovine NRAMP1 gene in cattle from herds with naturally occurring tuberculosis.  American Journal of Veterinary Research. Sept 2000. 61 (9) 1140-1144. ISSN: 0002-9645
NAL Call Number:  41.8 AM3A
Descriptors:  cattle, Mycobacterium bovis, tuberculosis, pathology, genes, disease resistance, susceptibility, genetic regulation, lesions, restriction fragment length polymorphism, RFLP, Texas, Mexico.

Blancou, J; Blancou, J.  Histoire de la surveillance et du controle des maladies animals transmissibles. [History of the monitoring and the control of transmissible animal diseases.] Office International des Epizooties; Paris; France. 2000. xiv + 366 pp. Note:  In French.
Descriptors:  history, symptoms, lesions, etiology, pathology, epidemiology, preventive measures, treatment, legislative aspects of transmissible animal diseases, sheep pox, foot and mouth disease, anthrax, distemper, glanders, contagious pleuropneumonia, rinderpest, African horse sickness, rabies, tuberculosis, tetanus, cysticercosis, dourine, fascioliasis, mange and scabies, endoparasites, cattle, dogs, goat, horse, sheep, swine, wild animals.

Bourne, J.; Donnelly, C.A.; Cox, D.R.; Gettinby, G.; McInerney, J.P.; Morrison, I.; Woodroffe, R. Bovine tuberculosis: towards a future control strategy. Veterinary Record. Feb 19, 2000. 146 (8) 207-210. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, tuberculosis, Mycobacterium bovis, disease control, research.

Bovine Tuberculosis Conference (4th:  2000:  Lansing, Mich.). Michigan. Dept. of Agriculture. Michigan. Dept. of Community Health. Michigan. Dept. of Natural Resources. United States. Dept. of Agriculture. Michigan State University. Proceedings from the Conference on Bovine Tuberculosis. Lansing, Mich.:  Bovine TB Eradication Project, [2000] 40 p.:  ill., maps. Note:  "The Bovine TB Eradication Project involves a multi-agency team of experts from:  Michigan Department of Agriculture, Michigan Department of Resources, Michigan Department of Community Health, United States Department of Agriculture, Michigan State University".
NAL Call Number:  SF967.T8.B683 2000
Descriptors:  tuberculosis in cattle, Michigan, government policy.

Castro-Ramos, M.; Errico, F.; Trelles, A.; Curbelo, R.; Laborde, M.  Mycobacterias aisladas de fuentes hidricas en la cuenca lechera de Uruguay.  [Mycobacteria associated with water sources in the milk basin of Uruguay.]  Veterinaria Montevideo.  1999/2000; 35(141): 21-23.  ISSN:  0376-4362.  Note:  In Spanish with an English summary.  
Descriptors:  dairy cattle, dairy farming, Mycobacterium species, Mycobacterium bovis, Mycobacterium terrae, Mycobacterium gastri, Mycobacterium triviale, Mycobacterium vaccae, microbial contamination of water, monitoring of drainage water and drinking water, disease prevalence, disease surveys, epidemiological surveys, epidemiology, Uruguay.

Coetsier, C.; Vannuffel, P.; Blondeel, N.; Denef, J.F.; Cocito, C.; Gala, J.L.  Duplex PCR for differential identification of Mycobacterium bovis, M. avium, and M. avium ssp. paratuberculosis in formalin-fixed paraffin-embedded tissues from cattle. Journal of Clinical Microbiology. 2000. 38 (8) 3048-3054.
NAL Call Number:  QR46.J6
Descriptors:  cattle, deletions, differential diagnosis, DNA sequencing, genes, identification, nucleotide sequences, open reading frames, paratuberculosis, PCR, polymerase chain reaction, tuberculosis, Mycobacterium avium ssp. paratuberculosis, Mycobacterium bovis, Mycobacterium tuberculosis.

Colby, M.M.; Smith, M.A.; Wineland, N.E.  A survey of brucellosis and tuberculosis surveillance among sheep and goats in the United StatesProceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000; ld 507
Descriptors:  brucellosis, goats, sheep, Brucella, Mycobacterium, disease surveillance, USA.

Collins, J.D.; Monaghan, M.; McGill, K.; Kelly, A.; Fitzsimons, T.  A longitudinal study of cattle found positive to the interferon gamma assay for Mycobacterium bovis infection.  Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: Id 197
Descriptors:  cattle, interferon gamma assay, diagnosis, Mycobacterium bovis, postmortem inspections.

Cvetnic, Z.; Lojkic, M.; Majnaric, D.; Krznaric, M.; Sanja, S.; Vera, K.J.  Tuberkuloza goveda u hrvatskoj s osvrtom na situaciju u Europi i u svijetu. [Bovine tuberculosis in Croatia with regards to the situation in Europe and in the World.]  Praxis Veterinaria, Zagreb. 2000. 48 (1-2) 33-39. Note:  In Croatian with an English summary.
Descriptors:  disease control, epidemiology, public health, tuberculosis, zoonoses, cattle, humans, Mycobacterium bovis, Croatia.

Das, P.K.; Biswal, D.N.; Misra, R.K. Infectious diseases of crossbred cattle. Dairy Development in Eastern India. National Dairy Research Institute, Eastern Regional Station, Kalyani, India, 2000. p. 46-52.
Descriptors:
  Brucella, Bacillus anthracis, anthrax, tuberculosis, Mycobacterium, rinderpest, rabies, foot and mouth disease, crossbred progeny crossbreds, cattle, Clostridium chauvoei, bluetongue virus, bovine diarrhea virus, India.

Delahay, R.J.; Langton, S.; Smith, G.C.; Clifton-Hadley, R.S.; Cheeseman, C.L. The spatio-temporal distribution of Mycobacterium bovis (bovine tuberculosis) infection in a high-density badger population. Journal of Animal Ecology. 2000. 69 (3) 428-441.
NAL Call Number:  410 J826
Descriptors:  European badger, Meles meles, disease reservoir, Mycobacterium bovis, cattle, Britain, Ireland, spatio-temporal distribution and variation, epidemiology, ecology, wild population density, disease prevalence, gender differences, persistence.

Duarte, A.L.S.; Goncalves, S.C.; Baldaia, M.J.; Mota, A.P. Inspeccao sanitaria de bovinos: abates e reprovacoes. [Bovine sanitary inspection: slaughtered animals and condemned stock.Veterinaria Tecnica. 2000. 10 (4) 18-23. Note:  In Portuguese.
Descriptors:  post slaughter, cattle, disease control, carcass condemnation, quality control of cattle products, bovine mastitis, meat inspection, respiratory diseases, pleuropneumonia, bovine leucosis, tuberculosis, Mycobacterium, Brucella, brucellosis, clinical aspects, bacterial diseases, endometritis, Portugal.

Emmerzaal, A.; Deleu, S. Rundertuberculose moeilijk vast te stellen en te bestrijden. {Cattle tuberculosis [caused by Mycobacterium bovis] is difficult to detect and to treat.} Veehouder en Dierenarts. 2000. 14 (2) 4-7. Note:  In Dutch.
Descriptors:  cattle, Mycobacterium bovis, diseases, diagnosis, cattle diseases.

Fathalla, M.; Hailat, N.; Lafi, S.Q.; Basha, E.A.; Al Sahli, A. An abattoir survey of gross reproductive abnormalities in the bovine genital tract in Northern Jordan. Israel Journal of Veterinary Medicine. 2000. 55 (3) 83-87.
NAL Call Number:  41.8 R25
Descriptors:  reproductive disorders, cattle, ovarian cysts, ovarian diseases, endometritis, pyometra, uterine diseases, tuberculosis, Mycobacterium, hematoma, cows, disease surveys, Jordan.

Gallagher, J. The bovine tuberculosis dilemma--what do we do next. Veterinary Journal. Sept 2000. 160 (2) 85-86. ISSN: 1090-0233
URL:
http://intl.elsevierhealth.com/journals/tvjl/
NAL Call Number:  SF601.V484
Descriptors:  cattle, tuberculosis, Mycobacterium bovis, disease transmission, disease control.

Gallagher, J.; Clifton-Hadley, R.S. Tuberculosis in badgers; a review of the disease and its significance for other animals. Research in Veterinary Science. Dec 2000. 69 (3) 203-217. ISSN: 0034-5288
NAL Call Number:  41.8 R312
Descriptors: 
Meles meles, tuberculosis, Mycobacterium bovis, pathology, pathogenesis, immunity diagnosis, excretion, epidemiology, wild animals, domestic animals, disease transmission, control methods, literature reviews.

Giacometti, M.; Wyss, D.; Nicolet, J.; Burnens, A.; Pfyffer, G.E.; Audige, L. Sind die gehegten Hirsche in der Schweiz frei von Tuberkulose? [Are deer kept [on farms] in Switzerland free from tuberculosis?] Forum Kleinwiederkauer Petits Ruminants. 2000. 48 (5) 8-9 (German), 9-10 (French). Note:  In German and French
Descriptors:  deer farming, animal diseases, Mycobacterium tuberculosis, mycobacterial diseases, zoonotic diseases, deer, Switzerland.

Griffin, J.M.; Williams, D.H.; Collins, J.D.  A compartmental model for the within-herd spread of M. bovis in Irish cattle herds.  Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: Id 188
Descriptors:  cattle, Mycobacterium bovis, intradermal tests, transmission within a cattle herd, model, Ireland.

Griffin, J.M.; Quigley, F.; Towey, K.P.; Costello, E.; Hammond, R.F.; McGrath, G.; Sleeman, D.P.; Collins, J.D.  A field trial to assess the impact of badger removal on tuberculosis levels in cattle in four geographical areas in Ireland.  Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000. 2000: Id 184
Descriptors:  badgers, cattle, bovine tuberculosis, Mycobacterium bovis, autopsy, control programs, disease surveillance, postmortem inspections, Ireland.

Grover, Sunita; Batish, V.K.; Grover, S.; Verma, R. (ed.); Sharma, N. (ed.); Varma, T.K. (ed.); Bagherwal, R.K. (ed.); Jaiswal, T.N. Diagnosis of tuberculosis in dairy herds by PCR. Advancements in Veterinary Science. Indian Association for the Advancement of Veterinary Research, Bareilly, India 2000. p. 81-91. Note: Indian Veterinary Congress, Izatnagar, India, 18-19 February 2000.
Descriptors:  dairy herds, diagnosis of tuberculosis, polymerase chain reaction, PCR, diagnostic techniques, Mycobacterium bovis, Mycobacterium tuberculosis.

Haagsma, J. Bovine tuberculosis. Manual of Standards for Diagnostic Tests and Vaccines. List A and B Diseases of Mammals, Birds and Bees. 2000. Ed. 4, 359-370. Office International des Epizooties, Paris, France.
NAL Call Number:  SF771 M36 2000
Descriptors:  clinical aspects, Mycobacterium bovis, bacteriology, clinical aspects, diagnositic techniques, immunization, lesions, postmortem examinations, tuberculin tests, tuberculosis vaccination, vaccine development.

Hadjiev, G. Kratak prikaz epizootioloske situacije u zivinarstvu Republike Bugarske. [Epidemiology of poultry in Bulgaria.] Zivinarstvo. 2000. 35 (8-9) 161. Note:  In Serbian.
Descriptors:
  Salmonella, Marek’s disease, tuberculosis, Mycobacterium, Newcastle disease virus, infectious diseases, epidemiology, poultry, Balkans.

Hammond, R.F.  Visualisation of the temporal and spatial patterns of tuberculin reactor disclosure in an area affected by the removal of badgers.  Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: Id 183
Descriptors:  cattle, badgers (Meles meles), wild animal disease reservoir, Mycobacterium bovis, disease control programs, postmortem inspections, Ireland.

Hancox, M. Cattle tuberculosis schemes: control or eradication. Letters in Applied Microbiology. July 2000. 31 (1) 87-93. ISSN: 0266-8254
NAL Call Number:  QR1.L47
Descriptors:  Mycobacterium bovis, disease prevention, eradication, control, plans.

Jorge, M.C.; Schettino, D.M.; Torres, P.; Bernardelli, A. Primera descripcion de infeccion concomitante de tuberculosis y paratuberculosis en ovinos lecheros en Argentina. [First description of concomitant infection with tuberculosis and paratuberculosis in dairy sheep in Argentina.] Revue Scientifique et Technique, Office International des Epizooties. 2000. 19 (3) 800-809. Note:  In Spanish with English and French summaries.
NAL Call Number:  SF781 R4
Descriptors:  tuberculosis, mixed infections, diagnosis, Mycobacterium avium ssp. paratuberculosis, Mycobacterium bovis, comparative intradermal tuberculin test, dairy sheep, differential diagnosis, paratuberculosis, Argentina.

Kaneene, J.B.; Fitzgerald, S.D.; Schmitt, S.; Miller, R.A.; Bruning-Fann, C.; O' Brien, D.; Judge, L.  Epidemiological studies of Mycobacterium bovis in wildlife and domestic livestock, Michigan, USA Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August-6-11, 2000.  2000: ld 580.
Descriptors:  cattle, goats, deer, Mycobacterium bovis, epidemiology, transmission of disease between domestic livestock and wild deer, Michigan, USA.

Kazwala, R.R.; Sharp, M.; Shirima, G.M.; Mfinanga, G.; Clevealand, S.; Ernest, E.M.; Buza, J.; Kambarage, D.M.  The prevalence of bovine tuberculosis in Rift Valley Districts based on single intradermal comparative tuberculin testing.  Tanzanian Veterinary Journal.  2000; 20: 136-140.  ISSN:  0856-1451
Descriptors:  11,274 cattle, 605 herds, Single Intradermal Comparative Tuberculin Testing (SICTT), prevalence of disease 0.93%, herd prevelance of 14%, control of disease at herd level, Rift Valley Districts, Tanzania.

Kohler, H.; Martin, G.; Schimmel, D. Immunologische Methoden zur Diagnostik der Rindertuberkulose -- aktueller Stand. [Immunological methods for the diagnosis of bovine tuberculosis -- state of the art.] Berliner und Munchener Tierarztliche Wochenschrift. 2000. 113 (10) 388-391. Note:  In German with an English summary.
NAL Call Number:  41.8 B45
Descriptors:diagnosis, Mybacterium bovis, tuberculosis, cattle diseases, skin tests, interferon, lymphocyte transformation.

Lauzi, S.; Pasotto, D.; Amadori, M.; Archetti, I.L.; Poli, G.; Bonizzi, L. Evaluation of the specificity of the gamma-interferon test in Italian bovine tuberculosis-free herds. Veterinary Journal.  July 2000. 160 (1) 17-24. ISSN: 1090-0233 
URL:
http://intl.elsevierhealth.com/journals/tvjl/
NAL Call Number:  SF601.V484          
Descriptors:  cattle, tuberculosis, interferon, diagnostic techniques, diagnostic value, Mycobacterium, Lombardy.

Leite, R.C.; Bressan, M. (ed.); Martins, C.E. (ed.); Vilela, D. Danos a producao de ruminante por doencas infecto-contagiosas reprodutivas. [Damage to ruminant production by reproductive infectious diseases.  EMBRAPA, Gado de Leite; Juiz de Fora; Brazil; 2000. p. 137-146. Note:  Simposio Sobre Sustentabilidade da Pecuaria deLeite no Brasil, 2000, Goiania, Brazil. In Portuguese.
NAL Call Number:  SF233 B6S87 2000
Descriptors:  cattle diseases, diagnosis, brucellosis, trichomoniasis, leptospirosis, bovine tuberculosis, Mycobacterium, leucosis, disease effects on reproduction, infectious diseases, campylobacteriosis, bacterial diseases, viral diseases.

Liebana, E.; Aranaz, A.; Aldwell, F.E.; Mcnair, J.; Neill, S.D.; Smyth, A.J.; Pollock, J.M. Cellular interactions in bovine tuberculosis: release of active mycobacteria from infected macrophages by antigen-stimulated T cells.  Immunology. 2000. 99 (1) 23-29.
NAL Call Number:  448.3 IM6
Descriptors:  cattle, Mycobacterium bovis infected macrophages invitro interaction with T lymphocytes, tuberculosis, immune response, lymphocytes, antigen stimulated peripheral blood mononuclear cells (PBMC) from infected cattle, uracil uptake.

Lightbody, K.A.; McNair, J.; Neill, S.D.; Pollock, J.M. IgG isotype antibody responses to epitopes of the Mycobacterium bovis protein MPB70 in immunised and in tuberculin skin test-reactor cattle. Veterinary Microbiology. 2000. 75 (2) 177-188.
NAL Call Number:  SF601 V44
Descriptors:  cattle, tuberculosis, Mycobacterium bovis protein MPB70, B-cell target, epitope level response, IgG1 responses, skin testing, tuberculin, immune response.

Lilenbaum, W. Atualizacao em tuberculose bovina. [Bovine tuberculosis in Brazil: a minireview.] Revista Brasileira de Medicina Veterinaria. 2000. 22 (4) 145-151. Note: In Portuguese with an English summary.
NAL Call Number:  SF604 R38
Descriptors:  reviews, tuberculosis, Mycobacterium bovis, disease control, Brazil.

Mackintosh, C.G.; Qureshi, T.; Waldrup, K.; Labes, R.E.; Dodds, K.G.; Griffin, J.F.T. Genetic resistance to experimental infection with Mycobacterium bovis in red deer (Cervus elaphus). Infection and Immunity. 2000. 68 (3) 1620-1625.
NAL Call Number:  QR1.I57
Abstract:  In a 3-year heritability study, 6 farmed red deer stags were selected from 39 on the basis of their differing responses to experimental challenge via the tonsillar sac with approximately 500 colony forming units of M. bovis. Two stags remained uninfected, 2 were moderately affected and 2 developed serious spreading tuberculosis (Tb). 70 offspring, bred from these 6 stags by artificial insemination using stored semen, were similarly challenged with M. bovis. The offspring showed patterns of response to M. bovis challenge similar to those of their sires, providing evidence for a strong genetic basis to resistance to Tb, with an estimated heritability of 0.48 (standard error, 0.096; P<0.01). This is the first time the heritability of Tb resistance in domestic livestock has been measured. The breeding of selection lines of resistant and susceptible deer will provide an ideal model to study the mechanisms of Tb resistance in a ruminant and could provide an additional strategy for reducing the number and severity of outbreaks of Tb in farmed deer herds. Laboratory studies to identify genetic and immunological markers for resistance to Tb are under way. Preliminary studies showed no associations between NRAMP or DRB genes and resistance to Tb in deer. Patterns of immune responses seen in resistant animals suggest that both innate and acquired pathways of immunity are necessary to produce the resistant phenotype.
Descriptors:  disease resistance, heritability, resistance to tuberculosis, bacterial diseases, Mycobacterium bovis,  farmed red deer, Cervus elaphus, immune responses, selective breeding.

McKenzie, J.S.; Pfeiffer, D.U.; Morris, R.S.  Spatial and temporal patterns of vector-borne tuberculosis infection in beef breeding cattle in New Zealand.  Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: ld 574.  
Descriptors:  beef cattle, Mycobacterium bovis, brushtailed possum, Trichosurus vulpecula, New Zealand.

McKenzie, J.S.; Pfeiffer, D.U.; Morris, R.S.  Application of habitat analysis and spatial analytical techniques to statistical modelling of possum-associated tb risk on farms.  Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11 2000.  2000: ld 575.
Descriptors:  cattle, Mycobacterium bovis, brushtailed possoms (Trichosurus vulpecula) habitat analysis, spatial analytical methods, GIS, New Zealand.

Manisha, Mathur; Hemant, Dadhich; Sharma, G.D.; Mathur, M; Dadhich, H. Histopathological observations on tuberculosis in kidneys of sheep. Indian Journal of Veterinary Pathology. 2000. 24 (2) 117-118.
NAL Call Number:  SF769 A1I48
Descriptors:  histopathology, kidneys, tuberculosis, Mycobacterium tuberculosis, sheep, Rajasthan, India.

Martin, S.W.; O'-Keeffe, J.; White, P.; Collins, J.D.; Edge, V.L.  Risk factors for tuberculosis in Irish cattle: the analysis of secondary data.  Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: Id 240
Descriptors:  cattle, bacterioses, bovine-tuberculosis, Mycobacterium bovis, lung disease, data banks, Eire, Irish Republic.

Mendez y Cazarin, M.D.; Tzintzun Rasco, R.; Val-Arreola, D. Evaluacion productiva, de efecto ambiental y de problemas relevantes en explotaciones lecheras de pequena escala. [Production evaluation, environmental effect and problems in small scale dairy farms.] Livestock Research for Rural Development. 2000. 12 (1) 1-10. Note:  In Spanish with an English summary.
NAL Call Number:  SF55 D44L582
Descriptors:  small scale dairy farms, production problems, SILFIRA computerized program, water quality, tuberculosis and brucellosis prevalence, contaminants, milk production, fecal contamination, Mexico.

Menzies, F.D.; Neill, S.D. Cattle-to-cattle transmission of bovine tuberculosis. Veterinary Journal.  Sept 2000. 160 (2) 92-106. ISSN: 1090-0233
URL:
http://intl.elsevierhealth.com/journals/tvjl/
NAL Call Number:  SF601.V484
Abstract:  In developed countries, Mycobacterium bovis infection in cattle is now mostly confined to the respiratory system, which reflects transmission and establishment of infection mainly by this route. A single bacillus transported within a droplet nucleus is probably sufficient to establish infection within the bovine lung. Infected cattle should always be considered as potential sources of infection, since studies have demonstrated that a significant proportion of tuberculous cattle excrete M. bovis. In general, the dynamics of M. bovis transmission are poorly understood and the conditions under which a tuberculous animal becomes an effective disseminator of infection are currently not defined although environmental contamination appears to be a less effective method of disease transmission. Field studies indicate a wide spectrum of transmission rates but generally the spread of M. bovis infection is still considered to be a relatively slow process. Slaughter of diseased cattle detected by tuberculin testing and at meat plant inspection has been shown to be an effective policy for tuberculosis eradication, provided there are no other reservoirs of infection and all involved in the cattle industry are committed to a policy of eradication. Epidemiological approaches, particularly case-control studies, seem to provide the best method for quantifying the relative importance of the various sources of M. bovis transmission to cattle and modelling techniques can be used to assist in the design of cost-effective control measures that may lead to tuberculosis eradication.
Descriptors:  cattle, disease transmission, tuberculosis, Mycobacterium bovis spread, disease control, literature reviews.

Milian-Suazo, F.; Salman, M.D.; Ramirez, C.; Payeur, J.B.; Rhyan, J.C.; Santillan, M. Identification of tuberculosis in cattle slaughtered in Mexico. American Journal of Veterinary Research. Jan 2000. 61 (1) 86-89. ISSN: 0002-9645
NAL Call Number:  41.8 AM3A
Descriptors:  dairy cattle, tuberculosis, Mycobacterium tuberculosis, carcasses, identification, meat inspection, geographical distribution, organs, lesions, disease prevalence, Mexico.

Milian-Suazo, F.; Salman, M.D.; Black, W.C.; Triantis, J.M.; Ramirez, C.; Payeur, J.B.; Torres, M.C.  Molecular epidemiologic analysis of Mycobacterium bovis isolates from Mexico. American Journal of Veterinary Research. 2000. 61 (1) 90-95. ISSN: 0002-9645
NAL Call Number:  41.8 AM3A
Abstract: 
M. bovis was isolated from various organs of 400 cattle slaughtered in 6 regions of Mexico and phylogenetic relationships among isolates were assessed using random amplified polymorphic DNA polymerase chain reaction (RAPD-PCR) fingerprinting. Most cattle were adult Holsteins from large herds that did not participate in a tuberculosis control programme. Four random primers and 2 selected primers were used in RAPD-PCR fingerprinting of 88 isolates. Pairwise genetic distance between isolates was obtained and subjected to cluster analysis with bootstrapping to test for levels of support. 98 different fragments were obtained; there was broad genetic diversity among isolates, and each isolate had a unique RAPD-genotype, including those originating from the same herd. Clustering by geographic location, affected organ or severity of lesion was not detected. Linkage disequilibrium analysis suggested that M. bovis was highly clonal and that mutations develop at a rapid rate among isolates. Use of RAPD-PCR could not differentiate M. bovis isolates by epidemiological characteristics or identify common sources of infection.
Descriptors:  post slaughter survey, Mycobacterium bovis, cattle, isolate genetics, RAPD-PCR, control programs, genetic distance, Mexico.

Monies, R.J. Tuberculous pneumonia and BVD in housed calves. Cattle Practice. 2000. 8 (2) 119-125.
NAL Call Number:  SF961 C37
Descriptors:  case reports, tuberculosis pneumonia, Mycobacterium, calves, cattle housing, immunosuppressive agents, histology, serology, diarrhea virus, UK.

Morrison, W.I.; Bourne, F.J.; Cox, D.R.; Donnelly, C.A.; Gettinby, G.; McInerney, J.P.; Woodroffe, R. Pathogenesis and diagnosis of infections with Mycobacterium bovis in cattle. Veterinary Record. Feb 26, 2000. 146 (9) 236-242. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, Mycobacterium bovis, tuberculosis, pathogenesis, disease transmission, diagnosis, diagnostic techniques, disease control, British Isles.

Munroe, F.A.; Dohoo, I.R.; McNab, W.B. Estimates of within-herd incidence rates of Mycobacterium bovis in Canadian cattle and cervids between 1985 and 1994. Preventive Veterinary Medicine. 2000. 45 (3-4) 247-256.
NAL Call Number:  SF601 P7
Descriptors:  beef and dairy cattle, deer, cervids, Mycobacterium bovis, within-herd incidence of disease, disease transmission, risk factors, tuberculosis, outbreaks, herds, bacterial diseases.

Neill, S.D.; Pollock, J.M. Testing for bovine tuberculosis--more than skin deep. Veterinary Journal.  July 2000. 160 (1) 3-5. ISSN: 1090-0233
URL: http://intl.elsevierhealth.com/journals/tvjl/
NAL Call Number:  SF601.V484
Descriptors:  cattle tuberculosis, skin tests, interferon, diagnostic techniques, Mycobacterium.

Neil, S.D.; Wedlock D.; Vesosky, B.; Skinner, M.A.; de Lisle, G.W.; Orme, I.M.; Buddle, B.M.; Vaccination of cattle with Mycobacterium bovis culture filtrate proteins and interleukin-2 for protection against bovine tuberculosis. Infection and Immunity. 2000. 68 (10) 5809-5815.
NAL Call Number:  QR1.I57
Abstract:  In this study vaccines prepared from culture filtrate proteins (CFP) of Mycobacterium bovis and interleukin-2 (IL-2) were tested in cattle for their capacity to stimulate immune responses and to protect against an intratracheal challenge with virulent M. bovis. Nine groups of cattle were vaccinated with combinations of different doses of CFP and bovine IL-2 mixed with a monophosphoryl lipid A (MPL) adjuvant. An additional group was vaccinated with M. bovis BCG. Immune responses in CFP-IL-2-vaccinated animals differed from those seen in BCG-vaccinated animals by inducing high antigen-specific antibody responses and low levels of gamma interferon and IL-2 released from purified protein derivative-stimulated whole-blood cultures. In a concurrent experiment, additional animals were added to the high-dose CFP-IL-2, MPL control, and BCG groups and these expanded groups of animals were challenged intratracheally with virulent M. bovis. Although the lung lesion scores were significantly lower for both the CFP-IL-2-and BCG-vaccinated groups compared to the MPL control group, the overall level of protection was greatest for the BCG-vaccinated animals. There were more animals with extrathoracic spread of disease in the CFP-IL-2 group than in the other groups. While vaccination of cattle with M. bovis CFP gave an encouraging reduction in tuberculous lesions and did not induced a delayed-type hypersensitivity response to PPD, future CFP vaccines must prevent any extrathoracic spread of disease.
Descriptors:  adjuvants, immunization, immune response, interferon, interleukin 2, tuberculosis, vaccination, vaccines, cattle, Mycobacterium bovis.

Norden, D.K.; Meyer, R.M.; Salman, M.D.  Evaluation of tuberculin tests in U.S. captive reindeer (Rangifer tarandus)-1991-1999.  Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: Id 394.
Descriptors:  captive reindeer, tuberculin testing for Mycobacterium, USA.

Nott, S.B.; Wolf, C. Dairy farm decisions on how to proceed in the face of TB. Staff Paper Department of Agricultural Economics, Michigan State University. 2000. No. 2000-39, 18 pp.
NAL Call Number:  HD1401 S46
Descriptors:  economic impacts, costs, dairy cattle, on farm decisions, Mycobacterium, disease control, depopulation of TB positive animals, economic analysis, tuberculosis, Michigan.

Ocepek, M.; Zdovc, I.; Cestnik, V. (ed.); Pogacnik, A. Rhodococcus equi kot vzrok granulomatoznih sprememb v bezgavkah prasicev, sumljivih na okuzbo z mikobakterijami. [Rhodococcus equi as a cause of granulomatous changes in lymph nodes of pigs with suspected avian tuberculosis.] Veterinarske Novice. 2000. 26 (Suppl. 1) 35-37.  Note:  6 Konferenca Slovenske Veterinarske Zveze, 24-25 November 2000, Brdo pri Kranju, Slovenia. In Slovenian with an English summary.
Descriptors:  tissues, mesenteric and mandibular lymph nodes, pigs, granulomatous lymphadenitis, histological examination, culture for tuberculosis, ACCUPROBE (Gen Probe), Mycobacterium avium complex, Rhodococcus equi colonies, Api Coryne, polymerase chain reaction for 16S rRNA, dual infections, Slovenia.

Pavlik, I.; Ayele, W.Y.; Dvorska, L.; Matlova, L.; Oktabcova, L.; Palecek, K.; Svec, V.; Konopa, M.; Docekal, J; Vraj, L. Mykobakterialni infekce prasat v Ceske republice v letech 1989-1999. [Mycobacterial infections of swine in the Czech Republic in 1989-1999.] Veterinarstvi. 2000. 50 (5) 194-198. Note:  In Czech with an English summary.
NAL Call Number:  41.8 V6439
Descriptors:  meat inspection, diagnosis, disease prevalence, tuberculosis, pigs, Mycobacterium avium, Mycobacterium intracellulare, Rhodococcus equi, Czech Republic.

Pinheiro, S.R.  Controle da tuberculose bovina versus tratamento. [Control vs. treatment of bovine tuberculosis cattle.] O Biologico. 2000. 62 (2) 157-160. Note:  In Portuguese with an English summary.
Descriptors:  bovine tuberculosis, diagnostic tests, treatment concerns, disease control, costs, implications to human health, Brazil.

Pollock, J.M.; Girvin, R.M.; Lightbody, K.A.; Clements, R.A.; Neill, S.D.; Buddle, B.M.; Andersen, P. Assessment of defined antigens for the diagnosis of bovine tuberculosis in skin test-reactor cattle. Veterinary Record.  June 3, 2000. 146 (23) 659-665. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle tuberculosis, Mycobacterium bovis, antigens, interferon, diagnostic value, skin tests, derivatives, diagnosis, purified protein derivative.

Reis, D.O.; Alves, F.; Coelho, H.E. Importancia do exame histopatologico para o diagnostico pos-morte de bovinos abatidos em frigorifico de Uberlandia, MG, 1987-1997. [Importance of the histopathological examination for the postmortem diagnosis of cold-stored cattle slaughtered at Uberlandia, MG, 1987-1997.] Higiene Alimentar. 2000. 14 (78-79) 23-27. Note:  In Portuguese with an English summary.
Descriptors:  cattle, 128 postmortem examinations, check on accuracy of diagnosis, Mycobacterium, tuberculosis, neoplasms, Brazil.

Rhodes, S.G.; Gavier-Widen, D.; Buddle, B.M.; Whelan, A.O.; Singh, M.; Hewinson, R.G.; Vordermeier, H.M. Antigen specificity in experimental bovine tuberculosis. Infection and Immunity. May 2000. 68 (5) 2573-2578. ISSN: 0019-9567
NAL Call Number:  QR1.I57
Abstract:  This report describes the kinetics of T-cell responses to a panel of mycobacterial antigens (PPD-M, PPD-A, ESAT-6, Ag85, 38kD, MPB64, MPB70, MPB83, hsp16.1, hsp65, and hsp70) following experimental infection of cattle with Mycobacterium bovis. Increased antigen-specific lymphocyte proliferation, gamma interferon, and interleukin-2 responses were observed in all calves following infection. Positive lymphocyte proliferation and cytokine responses to PPD-M and ESAT-6 were observed throughout the infection period studied. In contrast, responses to all other antigens were more variable and were not constantly present, suggesting that antigen cocktails rather than individual antigens should be used for immunodiagnosis. The detection of cytokine responses in the absence of lymphocyte proliferation, particularly during the early stages of infection, suggests a role for antigen-specific cytokine readout systems in the early identification of M. bovis infection in cattle.
Descriptors:  cattle, bacterial antigens, T lympnocytes, lympnocyte transformation, tuberculosis, antigens, cytokines, experimental-infection, immunodiagnosis, interferon, interleukin-2, Mycobacterium bovis.

Rhodes, S.G.; Palmer, N.; Graham, S.P.; Bianco, A.E.; Hewinson, R.G.; Vordermeier, H.M. Distinct response kinetics of gamma interferon and interleukin-4 in bovine tuberculosis. Infection and Immunity. Sept 2000. 68 (9) 5393-5400. ISSN: 0019-9567
NAL Call Number:  QR1.I57
Descriptors:  immune responses, gamma interferon, interleukin, cattle, tuberculosis, Mycobacterium.

Rojas, H.; Soto, A.; Oltra, O.; Salgado, M.; Badilla, J.; Urcelay, S.  A framework for local livestock services with official disease control programmes: the case of brucellosis and tuberculosis in Chile.   Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August-6-11,2000.  2000: ld 592.
Descriptors:  livestock, Brucella, Mycobacterium, pathogenic bacteria, control programs, Chile.

Rojas, H.; Belaer, J.; Urcelay, S.  Prevalence and herd-level risk factors of bovine brucellosis and tuberculosis in family dairy systems in central Chile.  Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: ld 591.  
Descriptors:  dairy cattle diseases, herd disease levels and risk factors, disease surveys, Brucella, Mycobacterium, Chile.

Roring, S.; Hughes, M.S.; Skuce, R.A.; Neill, S.D. Simultaneous detection and strain differentiation of Mycobacterium bovis directly from bovine tissue specimens by spoligotyping. Veterinary Microbiology. 2000. 74 (3) 227-236.
NAL Call Number:  SF601 V44
Descriptors:
  Mycobacterium bovis, bovine tuberculosis, rapid detection and strain typing, lesioned bovine lymph node specimens, PCR, spoligotyping, decontaminated and non-decontaminated lesioned lymph nodes, DNA, cattle.

Ryan, T.J.; Buddle, B.M.; de Lisle, G.W. An evaluation of the gamma interferon test for detecting bovine tuberculosis in cattle 8 to 28 days after tuberculin skin testing.  Research in Veterinary Science. Aug 2000. 69 (1) 57-61. ISSN: 0034-5288
NAL Call Number:  41.8 R312
Descriptors:  cattle tuberculosis, Mycobacterium bovis, interferon, diagnostic techniques, accuracy, tuberculin, skin tests.

Ryan, T.J.; Lisle, G.W. de; Buddle, B.M.; Livingstone, P.G.  Cattle tuberculosis: an evaluation of the gamma interferon assay in ancillary serial and parallel testing. Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: Id 79.
Descriptors:  cattle, Mycobacterium bovis, serological diagnosis, gamma interferon assay, New Zealand.

Ryan, T.; Livingstone, P. Risk analysis: movement of cattle from tuberculosis infected herds. Surveillance. 2000. 27 (1) 8-10.
NAL Call Number:  SF604.63 N45S87
Descriptors:
   Mycobacterium, cattle, tuberculosis, diagnosis, disease control, transmission factors, New Zealand.

Salamon, H.; Kato-Maeda, M.; Small, P.M.; Drenkow, J.; Gingeras, T.R. Detection of deleted genomic DNA using a semiautomated computational analysis of GeneChip data. Genome Research. 2000. 10 (12) 2044-2054.
NAL Call Number:  QP606 D46P34
Descriptors:
Mycobacterium, genome analysis, genetic polymorphism, deletions, data analysis, DNA hybridization, algorithms.

Sanderson, M.W.; Dargatz, D.A.; Garry, F.B. Biosecurity practices of beef cow-calf producers. Journal of the American Veterinary Medical Association. 2000. 217 (2) 185-189. ISSN: 0003-1488
NAL Call Number:  41.8 AM3
Descriptors:  security concerns, management practices, testing imported cattle, brucellosis, Mycobacterium paratuberculosis, bovine viral diarrhoea, tuberculosis, potential for feed contamination, questionnaires, quarantine practices, vaccine programs, veterinarians as educators.

Sauter-Louis, C.M.; Morris, R.S.; Wilson, P.R.; Pfeiffer, D.U.; Carter, C.; Rhodes, T.  Intervention studies to assess the efficiency of on-farm control programs against tuberculosis in New ZealandProceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: Id 247
Descriptors:  cattle, disease control programs, pasturing, efficiency, Mycobacterium bovis, New Zealand.

Sauter-Louis, C.M.; Morris, R.S.; Wilson, P.R.; Pfeiffer, D.U.  The development of motivational incentives for farmers to achieve tuberculosis control in New Zealand Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics, Breckenridge, Colorado, USA, August 6-11, 2000.  2000: Id 246.
Descriptors:  cattle tuberculosis, Mycobacterium bovis, control programs, New Zealand.

Scacchia, M.; Lelli, R.; Petrini, A.; Prencipe, V.; Calistri, P.; Giovannini, A. Use of innovative methods in the eradication of bovine tuberculosis.  Journal of Veterinary Medicine, Series B.  June 2000. 47 (5) 321-327. ISSN: 0931-1793
NAL Call Number:  41.8 Z52
Descriptors:  cattle, Mycobacterium, tuberculosis, disease prevention, strains, frequency, detection, skin tests, diagnosis, false positive results, herds, infections, growth, interferon, diagnostic techniques, infected herd screening.

Seva, J.; Hernandez, D.; Bernabe, A.; Pallares, F.J.; Navarro, J.A. Immunophenotypical characterization of the lymphocyte infiltrate in caprine pulmonary tuberculosis.  Journal of Comparative Pathology. Aug/Oct 2000. 123 (2/3) 96-103. ISSN: 0021-9975
NAL Call Number:  41.8 J82
Descriptors:  goats, tuberculosis, T lymphocytes, B lymphocytes, characterization, Mycobacterium, phenotypes, disease course, lesions, lungs, lymph nodes.

Shah, D.H.; Rishendra-Verma.  Tuberculosis in sheep and goat: an update.  Intas Polivet. 2000; 1(2): 185-189.  ISSN:  0972-1738
Descriptors:  goats, Mycobacterium avium, Mycobacterium bovis, Mycobacterium tuberculosis, susceptibility to disease, clinical aspects, differential diagnosis, disease control, disease transmission, India.

Singh, B.P.; Chauhan, R.S. Common diseases of the calves and their prevention. Pashudhan. 2000. 15 (7) 1.
NAL Call Number:  SF604 P27
Descriptors:  calves, disease prevention, diarrhea, pneumonia, joint diseases, diphtheria, encephalitis, tuberculosis, disease control, Theileria annulata, Mycobacterium bovis, cattle.

Sreevatsan, S.; Bookout, J.B.; Ringpis, F.; Perumaalla, V.S.; Ficht, T.A.; Adams, L.G.; Hagius, S.D.; Elzer, P.H.; Bricker, B.J.; Kumar, G.K.; Rajasekhar, M.; Isloor, S.; Barathur, R.R. A multiplex approach to molecular detection of Brucella abortus and/or Mycobacterium bovis infection in cattle. Journal of Clinical Microbiology. July 2000. 38 (7) 2602-2610. ISSN: 0095-1137
NAL Call Number:  QR46.J6
Descriptors:  polymerase chain reaction, milk secretions, Brucella abortus, Mycobacterium bovis, tuberculosis, diagnosis, nasal secretions.

Tabosa, I.M.; Trindade, V.M.; Vale, G.M.G.; de Medeiros-Dantas, A.F.; Vieira, J.M.; de Medeiros, M.B.A.; de Azevedo, E.O.; de Melo, M.A.; Andrade, M.G.; de Souza, S.B.; da Silva-Medeiros, L.; Rodrigues, R.D.; Xavier, S.D. Ocorrencia de tuberculose em bovinos abatidos no matadouro municipal de Patos - Paraiba - Brasil. [Occurrence of tuberculosis in cattle slaughtered in the Patos municipal slaughter house - Paraiba - Brazil.] Revista Brasileira de Ciencia Veterinaria. 2000. 7 (1) 61-62. Note:  In Portuguese with an English summary.
Descriptors:  cattle, post-slaughter survey, bovine tuberculosis, histochemical and bacterial tests, macroscopic lesions, Mycobacterium, Brazil.

Tamba, M.; Natalini, S.; Mattioli, R.; Serra, P.; Palmonari, F. Applicazione del D.LG. 196/1999: risultati di un'indagine conoscitiva negli allevamenti bovini della provincia di Bologna. [Enforcement of Dir. 97/12/CE: results of a survey in cattle herds of Bologna Province, Italy.] Selezione Veterinaria. 2000. No. 3, 153-159. Note:  In Italian with an English summary.
NAL Call Number:  241.71 B75
Descriptors:  cattle, epidemiological survey, disease prevalence, surveillance system, tuberculosis, brucellosis, leucosis, disease control, Mycobacterium, Bologna, Italy.

UK, MAFF. Animal Health 2000. Report of the Chief Veterinary Officer. 2000. Ministry of Agriculture, Fisheries and Food (MAFF), London, UK
Descriptors: 
zoonotic disease, public health, disease prevention and control, animal welfare, BSE, tuberculosis, Mycobacterium, pets, livestock, transport, slaughter, UK.

Vordermeier, H.M.; Cockle, P.J.; Whelan, A.O.; Rhodes, S.; Hewinson, R.G. Toward the development of diagnostic assays to discriminate between Mycobacterium bovis infection and bacille Calmette-Guerin vaccination in cattle. Clinical Infectious Diseases. 2000. 30 (Suppl. 3) S291-S298.
NAL Call Number:  RC111 R4
Descriptors:  cattle, diagnosis, assays, vaccines, immunization, Mycobacterium bovis, Mycobacterium bovis BCG strain.

Wahlstrom, H.; Carpenter, T.; Giesecke, J.; Andersson, M.; Englund, L.; Vagsholm, I. Herd-based monitoring for tuberculosis in extensive Swedish deer herds by culling and meat inspection rather than by intradermal tuberculin testing. Preventive Veterinary Medicine.  Jan 20, 2000. 43 (3) 103-116. ISSN: 0167-5877
NAL Call Number:  SF601.P7
Descriptors:  deer farming herds, herd disease monitoring, Mycobacterium bovis, culling, diagnostic techniques, post slaughter meat inspection, zoonoses, disease transmission, Reed-Frost, simulation models, detection, Sweden.

Wards, B.J.; de Lisle, G.W.; Collins, D.M. An esat6 knockout mutant of Mycobacterium bovis produced by homologous recombination will contribute to the development of a live tuberculosis vaccine. Tubercle and Lung Disease. 2000. 80 (4-5) 185-189.
Descriptors:  esat6 knockout mutant, virulent strain of M. bovis, guineapigs, inoculated, mutant/parent strain comparison, intradermal skin tests, bovine purified protein derivative, recombinant ESAT6 protein, Southern blot, PCR, vaccine development, live vaccines.

Waters, W.R.; Palmer, M.V.; Pesch, B.A.; Olsen, S.C.; Wannemuehler, M.J.; Whipple, D.L. Lymphocyte subset proliferative responses of Mycobacterium bovis-infected cattle to purified protein derivative. Veterinary Immunology and Immunopathology. 2000. 77 (3-4) 257-273. ISSN: 0165-2427
NAL Call Number:  SF757.2.V38
Descriptors:  lymphocytes, lymphocyte transformation, immune response, tuberculosis, T lymphocytes, cell mediated immunity, Mycobacterium bovis, cattle diseases.

Waters W.R.; Palmer, M.V.; Pesch, B.A.; Olsen, S.C.; Wannemuehler, M.J.; Whipple, D.L. MHC class II-restricted, CD4+ T-cell proliferative responses of peripheral blood mononuclear cells from Mycobacterium bovis-infected white-tailed deer. Veterinary Immunology and Immunopathology. 2000. 76 (3-4) 215-229. ISSN: 0165-2427
NAL Call Number:  SF757.2.V38
Descriptors:  white-tailed deer, wildlife, disease reservoir, Mycobacterium bovis, cattle, predators, humans, CD4+subset lymphocytes, CD8+, gammadelta TCR+, B cells, immune response, lymphocyte transformation, monoclonal antibodies, major histocompatibility component.

Wedlock, D.N.; Vesosky, B.; Skinner, M.A.; de Lisle, G.W.; Orme, I.M.; Buddle, B.M. Vaccination of cattle with Mycobacterium bovis culture filtrate proteins and interleukin-2 for protection against bovine tuberculosis.  Infection and Immunity. Oct 2000. 68 (10) 5809-5815. ISSN: 0019-9567
NAL Call Number:  QR1.I57
Abstract:  In this study vaccines prepared from culture filtrate proteins (CFP) of Mycobacterium bovis and interleukin-2 (IL-2) were tested in cattle for their capacity to stimulate immune responses and to protect against an intratracheal challenge with virulent M. bovis. Nine groups of cattle were vaccinated with combinations of different doses of CFP and bovine IL-2 mixed with a monophosphoryl lipid A (MPL) adjuvant. An additional group was vaccinated with M. bovis BCG. Immune responses in CFP-IL-2-vaccinated animals differed from those seen in BCG-vaccinated animals by inducing high antigen-specific antibody responses and low levels of gamma interferon and IL-2 released from purified protein derivative-stimulated whole-blood cultures. In a concurrent experiment, additional animals were added to the high-dose CFP-IL-2, MPL control, and BCG groups and these expanded groups of animals were challenged intratracheally with virulent M. bovis. Although the lung lesion scores were significantly lower for both the CFP-IL-2-and BCG-vaccinated groups compared to the MPL control group, the overall level of protection was greatest for the BCG-vaccinated animals. There were more animals with extrathoracic spread of disease in the CFP-IL-2 group than in the other groups. While vaccination of cattle with M. bovis CFP gave an encouraging reduction in tuberculous lesions and did not induce a delayed-type hypersensitivity response to PPD, future CFP vaccines must prevent any extrathoracic spread of disease.
Descriptors:
  Mycobacterium, bacterial antigens, protective antigens, vaccine development, antibody formation, T lymphocytes.

Weinhaupl, I.; Schopf, K.C.; Khaschabi, D.; Kapaga, A.M.; Msami, H.M. Investigations on the prevalence of bovine tuberculosis and brucellosis in dairy cattle in Dar es Salaam region and in zebu cattle in Lugoba area, Tanzania.  Tropical Animal Health and Production. June 2000. 32 (3) 147-154. ISSN: 0049-4747
NAL Call Number:  SF601.T7
Descriptors:  dairy cows, zebu, disease prevalence, Mycobacterium bovis, Brucella abortus, brucellosis, delayed type hypersensitivity, Mycobacterium tuberculosis, serological surveys, milkborne diseases, Tanzania.

Whipple, D.L.; Mitchell, M.V.; Brown, C. (ed.); Bolin, C. Reemergence of tuberculosis in animals in the United States. Emerging Diseases of Animals. 2000. p. 281-299. American Society for Microbiology (ASM), Washington, USA.
NAL Call Number:  SF781 E53 2000
Descriptors:  cattle, disease prevention and control, disease transmission, epidemiology, reviews, wild animals, Mycobacterium bovis, US.

Wolf, C.; Harsh, S.; Lloyd, J. Valuing losses from depopulating Michigan dairy herds. Staff Paper, Department of Agricultural Economics, Michigan State University. 2000. No. 2000-10, 18 pp.
NAL Call Number:  HD1401 S46
Descriptors:  animal diseases, dairy cattle, disease control and eradication, depopulation, farm level economic impacts, livestock numbers, losses, methodology, returns, valuation, Michigan.

Wyss, D.; Giacometti, M.; Nicolet, J.; Burnens, A.; Pfyffer, G.E.; Audige, L. Farm and slaughter survey of bovine tuberculosis in captive deer in Switzerland. Veterinary Record. Dec 16, 2000. 147 (25) 713-717. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  deer, Mycobacterium bovis, Mycobacterium tuberculosis, tuberculosis, farm surveys, disease surveys, lymph nodes, livestock numbers, Switzerland.

Yearsley, D.; O'Rourke, J.; Griffin, M.; Nearney, M.; Egan, J. Detection of Mycobacterium tuberculosis complex organisms in tissue samples from bovine lymph nodes: comparison of two rapid methods and Lowenstein-Jensen medium with the Bactec 460 TB system. Irish Veterinary Journal. 2000. 53 (1) 29-31.
NAL Call Number:  41.8 IR4
Descriptors:  cattle, lymph node tissue samples, rapid diagnostic methods, comparison study, Lowenstein-Jensen (L-J) medium, Bactec 460 TB system, tuberculosis, histopathology, Mycobacterium tuberculosis, Mycobacterium bovis.

Yener, Z.; Erer, H. Konya mezbahalarinda kesilen sigirlarda bobrek lezyonlari uzerinde patolojik incelemeler. [The pathology of kidney abnormalities in cattle slaughtered at Konya Slaughterhouses.] Veteriner Bilimleri Dergisi. 2000. 16 (2) 63-74. Note:  In Turkish with an English summary.
Descriptors:  cattle, post slaughter examination, pathology, a number of conditions listed, tuberculosis, amyloid deposition, nephritis, hemoglobinuric nephrosis, granulomatous nephritis, Turkey.

1999

Abdala, A.A.; Tarabla, H.D.; Bertero, S.; Torres, P. Vigilancia epidemiologica de tuberculosis bovina en el Dpto. Castellanos, Santa Fe (Argentina).  [Epidemiological surveillance of bovine tuberculosis in the Castellanos region, Santa Fe (Argentina).] Revista de Medicina Veterinaria, Buenos Aires. 1999. 80 (5) 357-360. Note:  In Spanish with an English summary.
NAL Call Number:  41.8 B86
Descriptors: 
Mycobacterium tuberculosis, bovine tuberculosis, slaughter houses, Friesian cows, cattle, lesions, lungs, lymph nodes, post slaughter examinations, herds, epidemiological surveys, disease surveys, epidemiology, bacterial diseases, Argentina.

Abdala, A.A.; Tarabla, H.D.; Bertero, S.; Torres, P. Vigilancia epidemiologica de la tuberculosis bovina en el departamento Castellanos, Santa Fe. [Epidemiological surveillance of bovine tuberculosis in the department of Castellanos, Santa Fe].  Revista Argentina de Microbiologia. 1999. 31 (Suppl. 1) 13-14. NoteSegundo Ttaller Internacional sobre Infecciones Humanas y Animales Producidas por Clamidias, Micobacterias, Brucelas y Borrelias, Buenos Aires, 25 Junio-4 Julio, 1997. In Spanish.
Descriptors:  cattle, Mycobacterium bovis, monitoring, epidemiology, tuberculosis infections, disease prevalence, surveillance, Argentina.

Ahmed, A.S.N.; Khan, J.R.; Ganai, N.A. DNA amplification assay for rapid detection of bovine tubercle bacilli in semen.  Animal Reproduction Science.  Oct 31, 1999. 57 (1/2) 15-21. ISSN: 0378-4320
NAL Call Number:  QP251.A5
Descriptors:  cattle, bulls, semen, Mycobacterium tuberculosis, polymerase chain reaction, detection, diagnostic techniques, shedding, artificial insemination, Mycobacterium bovis.

Al Sadi, H.I.; Al Sultan, I.I. A report of two cases of bovine tuberculosis in Ninevha province. Iraqi Journal of Veterinary Sciences. 1999. 12 (2) 379-382. Note:  In English with an Arabic summary.
Descriptors:  cattle, Mycobacterium, tuberculosis, case reports, pathology, histopathology, Iraq.

Anonomyous. Complexities of controlling TB. Veterinary Record.  May 1, 1999. 144 (18) 485. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, tuberculosis, Mycobacterium, disease control, badgers, Meles meles, government policy, UK.

Anonomyous. Control of bovine TB: a gap to be filled.  Veterinary Record. July 31, 1999. 145 (5) 117. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, tuberculosis, disease control, Mycobacterium, UK.

Anonmyous.  Northeast Michigan surveillance activities for bovine tuberculosis in the livestock and free-ranging deer populations. Update:  September 15, 1998.  Dairy, Food and Environmental Sanitation.  1999. 19 (1) 35-38.
NAL Call Number:  SF221 D342
Descriptors:  cattle, deer, Mycobacterium bovis, Procyon lotor; Odocoileus virginianus, tuberculosis, livestock, wild animals, disease control, disease prevalence, Michigan.

Anonomyous. Searching for a solution. Veterinary Record.  Oct. 16, 1999. 145 (16) 441. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, tuberculosis, disease control, disease statistics, Mycobacterium, Great Britain.

Anonomyous. TB and the short term. Veterinary Record.  Mar 20, 1999. 144 (12) 301. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, badgers, Meles meles, tuberculosis, disease control, Mycobacterium bovis, Great Britain.

Arellano-Reynoso, B.; Ramirez-Casillas, I.C.; Diaz-Aparicio, E.; Valero-Elizondo, G.; Santillan-Flores, M.A.  Diagnostico de tuberculosis en hatos de caprinos empleando la prueba intradermica doble comparativa y cultivo bacteriologico. [Diagnosis of tuberculosis in goat flocks using the double intradermal test and bacteriology.Tecnica Pecuaria en Mexico. 1999. 37 (1) 55-58. Note: In Spanish with an English summary.
NAL Call Number:  49 T222
Descriptors:  goats, tuberculosis survey, disease prevalences, double intradermal test, purified protein derivative, PPD, necropsy, tissue analysis, asymptomatic infections, Mycobacterium fortuitum, Mycobacterium avium ssp. paratuberculosis, Mycobacterium bovis, Mycobacterium vaccae, Mexico.

Atsanda, N.N.; Agbede, S.A. A survey for brucellosis, tuberculosis and cysticercosis in cattle slaughtered in Ibadan and Maiduguri abattoirs. Nigerian Veterinary Journal. 1999. 20 (1) 61-66.
Descriptors:  post-slaughter survey, cattle, diseases prevalence, brucellosis, tuberculosis and cysticercosis, zoonotic diseases, metacestodes, parasites, helminths, Taenia, Mycobacterium, Nigeria.

Bachvarova, Y.; Kostov, G.; Lilkova, N.; Savova, S.; Bardarov, I.; Baitchev, Z. Occurrence of the non-specific tuberculin reactions in cattle and nature of the accompanying pathomorphological and bacterial findings. Bulgarian Journal of Veterinary Medicine. 1999. 2 (1) 33-39.
Descriptors:  cattle, tuberculin skin tests, Mycobacterium, abscesses, pathology, parasites, sarcocystosis, leucosis, actinomycosis, pericarditis, diagnosis, tuberculosis, delayed type hypersensitivity, diagnostic techniques, bacterial diseases, Actinomyces, Echinococcus, Fasciola, Arcanobacterium pyogenes, Mycobacterium tuberculosis.

Bicknell, K.B.; Wilen, J.E.; Howitt, R.E. Public policy and private incentives for livestock disease control. Australian Journal of Agricultural and Resource Economics. Dec 1999. 43 (4) 501-521. ISSN: 1364-985X
NAL Call Number:  HD1401.A89
Descriptors:  cattle, Didelphidae, bovine tuberculosis, Mycobacterium, disease control, dynamic bioeconomic models, wildlife, disease vectors, public sector, incentives, effectiveness of control policies, New Zealand.

Black, H.; Simper, J.M.; Bloom, D.; Bloom, K. A behaviour study on the potential for direct transmission of tuberculosis from possums (Trichosura vulpecula) to alpacas (Lama pacos), and the converse from alpacas to possums. New Zealand Veterinary Journal. 1999. 47 ( 6) 204-206.
NAL Call Number:  41.8 N483
Descriptors:  alpaca farm, tuberculosis, Mycobacterium, behavior study, impacts on disease transmission, interactions with brushtailed possums, possible aerosol transmission, stamping behavior, nose to nose contact, New Zealand.

Buddle, B.M.; Parlane, N.A.; Keen, D.L.; Aldwell, F.E.; Pollock, J.M.; Lightbody, K.; Andersen, P. Differentiation between Mycobacterium bovis BCG-vaccinated and M. bovis-infected cattle by using recombinant mycobacterial antigens. Clinical and Diagnostic Laboratory Immunology. 1999. 6 (1) 1-5.
Descriptors:  cattle, Mycobacterium bovis, vaccination, tuberculosis, recombinant antigens-- MPB59, MPB64, MPB70 and ESAT-6, whole blood gamma interferon assay, skin test, experimental infection of calves with M. bovis, bacterial diseases, attempt to determine BCG vaccination, non-vaccinationed groups, comparison study.

Caley, P.; Hickling, G.J.; Cowan, P.E.; Pfeiffer, D.U.   Effects of sustained control of brushtail possums on levels of Mycobacterium bovis infection in cattle and brushtail possum populations from Hohotaka, New Zealand. New Zealand Veterinary Journal. 1999. 47 (4) 133-142.
NAL Call Number:  41.8 N483
Descriptors:  cattle, brushtail possum, wildlife disease reservoir, population density, tuberculosis, Mycobacterium bovis, pest control, disease prevalence, disease transmission, epidemiology, Trichosurus vulpecula, pest population levels and control, New Zealand.

Caro, R.R.; Gutierrez, L.R. Prevencion de enfermedades infecciosas en equinos. [Prevention of equine infectious diseases.] Veterinaria Argentina. 1999. 16 (158) 592-606. Note:  In Spanish with an English summary.
NAL Call Number:  SF604 V463
Descriptors:  horses, equine infectious diseases, disease control and prevention, epidemiology, reviews, tetanus, brucellosis, tuberculosis, anthrax, leptospirosis, botulism, salmonellosis, encephalitis, rabies, Mycobacterium, influenza, infectious anemia and arteritis viruses, Argentina.

Carter, C.E.; Budge, G. The national cattle and deer ID programme.  Publication –Veterinary Continuing Education, Massey University. 1999. No. 189, 177-181. 29th Seminar of the Society of Sheep and Beef Cattle Veterinarians NZVA, Hastings, New Zealand, 1-3 March 1999. Note:  A conference proceedings.
NAL Call Number:  SF604 P82
Descriptors:  identification, deer, cattle, identification program, tuberculosis, Mycobacterium.

Cassidy, J.P.; Bryson, D.G.; Pollock, J.M.; Evans, R.T.; Forster, F.; Neill, S.D. Lesions in cattle exposed to Mycobacterium bovis-inoculated calves. Journal of Comparative Pathology. 1999. 121 (4) 321-337.
NAL Call Number:  41.8 J82
Descriptors:  cattle tuberculosis, experimental infection, disease transmission, pathogenesis, pathology, lung lesions, calves, histopathology, lymphocyte transformation, interferon, models, immune response, bacterial diseases, Mycobacterium bovis.

Cassidy, J.P.; Bryson, D.G.; Neill, S.D. Tonsillar lesions in cattle naturally infected with Mycobacterium bovis. Veterinary Record. 144 (6) 139-142. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, Mycobacterium bovis, lesions, tonsils, tuberculosis, respiratory system, lymph nodes, histopathology.

Cho, Y.S.; Kim, J.M.; Jung, S.C.; Woo, S.R.; Kim, J.Y.; Yoo, H.S.; Park, Y.H.; Ahn, J.S. Diagnosis of bovine tuberculosis by single intradermal comparative tuberculin test and gamma-interferon assay. Korean Journal of Veterinary Research. 1999. 39 (6) 1119-1125. Note:  In Korean with an English summary.
NAL Call Number:  41.9 T12
Descriptors:  cattle, tuberculin skin test, Mycobacterium bovis, Mycobacterium avium, tuberculosis, diagnosis, diagnostic techniques, guineapigs, Korea Republic.

Cobb, A.J.; Frothingham, R. The GroES antigens of Mycobacterium avium and Mycobacterium paratuberculosis. Veterinary Microbiology. 1999. 67 (1) 31-35. 
NAL Call Number:  SF601 V44
Descriptors:
  Mycobacterium avium, Mycobacterium leprae, Mycobacterium tuberculosis, Mycobacterium avium ssp. paratuberculosis, heat shock protein genes cloned and sequenced, GroES, immunodominant epitopes, conserved sequences, antigens.

Coleman, J.D.; Thomas, M.D.; Pracy, L.T.; Hansen, Q. Fluctuations in possum numbers in the Pararaki Valley, Haurangi State Forest Park. Science for Conservation. Department of Conservation; Wellington; New Zealand. 1999. No. 128, 16 pp.
Descriptors:  brushtail possums, forests, colonization, trapping, pests, introduced species, wild animals, vertebrate pests, forest pests, nature conservation, livestock animal diseases, tuberculosis, population dynamics, national parks, reservoir hosts, Trichosurus vulpecula, New Zealand.

Coleman, J.D.; Cooke, M.M.; Jackson, R.; Webster, R. Temporal patterns in bovine tuberculosis in a brushtail possum population contiguous with infected cattle in the Ahaura Valley, Westland. New Zealand Veterinary Journal. 1999. 47 (4) 119-124.
NAL Call Number:  41.8 N483
Descriptors:  brushtail possum, Trichosurus vulpecula, temporal and spatial patterns, contiguously with livestock, disease transmission trapping study, New Zealand, tubucular lesions, wildlife disease reservoirs, population size related to incidence of disease.

Collins, C.H.; Grange, J.M. Transmission of bovine TB in cattle: A critical reappraisal.  Letters in Applied Microbiology. Aug 1999. 29 (2) 146. ISSN: 0266-8254. Note:  Discussion of the article "Transmission of bovine TB:  A critical reappraisal" by M. Hancox this journal, 28 (3), p. 242-244, Mar 1999.
NAL Call Number:  QR1.L47
Descriptors:  cattle, tuberculosis, disease transmission, Mycobacterium bovis, letter.

Cooke, M.M.; Buddle, B.M.; Aldwell, F.E.; McMurray, D.N.; Alley, M.R. The pathogenesis of experimental endo-bronchial Mycobacterium bovis infection in brushtail possums (Trichosurus vulpecula). New Zealand Veterinary Journal. 1999. 47 (6) 187-192.
NAL Call Number:  41.8 N483
Descriptors:  experimental infection, brushtail possums, Mycobacterium bovis, necropsy of lesions, various internal organs, peripheral blood lymphocyte blastogenic responses, pathogenesis.

Cross, M.L.; Qureshi, T.; Mackintosh, C.G. Oxidative responses in ferret macrophages. Veterinary Immunology and Immunopathology. Feb 1, 1999. 67 (2) 171-184. ISSN: 0165-2427
NAL Call Number:  SF757.2.V38
Abstract:  Although the basic function of T and B lymphocytes in ferrets has been known for some time, the function of mononuclear phagocytes has not been described in this species. The present study has characterised basic oxidative responses in ferret macrophages, and has investigated the effects of endogenous and exogenous modulators of macrophage function on oxidative capacity in vitro. Macrophages derived from the blood or lungs of ferrets were shown capable of generating the reactive oxygen intermediate (ROI) molecules superoxide and hydrogen peroxide, and secreting a lysosomal enzyme (acid phosphatase), in response to appropriate stimuli. A T cell supernatant (derived from mitogen-stimulated peripheral blood lymphocytes) was able to activate both blood-and lung-derived macrophages for enhanced ROI production, while specific ROI inhibitors (superoxide dismutase and catalase) were able to partially ablate ROI activity. The accumulation of nitrite in culture supernatants, as an indicator for the production of reactive nitrogen intermediates, could not be demonstrated by ferret macrophages derived from either tissue source. In contrast to the enhancing effects of TCS on the oxidative function of blood-derived macrophage, exposure to bacterial LPS caused marked suppression of ROI and lysosomal enzyme production by these cells. Finally, the generation of superoxide anion, following phagocytosis of live or heat-killed Mycobacterium bovis or zymosan, indicated that ROI production in response to phagocytic stimulation was relatively weak in ferret blood-derived macrophages. These results are discussed in relation to the study of immune function in a novel species, and with particular reference to research into tuberculosis (Tb), since ferrets are important wildlife vectors of bovine Tb in New Zealand.
Descriptors:  ferrets, Mustelo furo, oxidation, macrophages, T lymphocytes, B lymphocytes, phagocytes, oxides, acid phosphatase, secretion, superoxide dismutase, catalase, activity, nitrite, culture filtrates lipopolysaccharides.

Das, S.K.; Bhatia, S. Gamma-interferon bioassay for detection of bovine tuberculosis in cattle: kinetics of production and dose response in whole blood culture. Indian Journal of Experimental Biology. 1999. 37 (10) 1039-1041.
NAL Call Number:  442.8 IN2
Descriptors:
  Mycobacterium bovis, PPD sensitized lymphocytes, release gamma interferon, kinetics, T lymphocytes, cattle, detection.

De N. Gomes, N.B.; Rostagno, M.H.; von G. do Santos, G.J.; Aguiar, P.H.P. Frequencia de lesoes em bovinos abatidos no matadouro municipal da cidade de Lavras, MG. [Frequency of lesions in cattle slaughtered at the municipal abattoir in Lavras, Minas Gerais, Brazil.] Veterinaria Noticias. 1999. 5 (1) 41-46. Note:  In Portuguese with an English summary.
NAL Call Number:  SF604 V484
Descriptors:  cattle, post slaughter, lesions on various organs, levels of tuberculosis and cystecercosis,
Mycobacterium, Brazil.

De Oliveira, P.R.; de A. Ribeiro, S.C.; Garcia, C.A.; de O. Reis, D. Prevalencia e tendencia da tuberculose em bovinos abatidos em Uberlandia - MG, de 1984 a 1996. [Prevalence and tendency of tuberculosis in slaughtered bovines in Uberlandia-MG, 1984-1996.] Bioscience Journal. 1999. 15 (1) 39-48. Note:  In Portuguese with an English summary.
NAL Call Number:  QH301 R485
Descriptors:  cattle, tuberculosis, post slaughter survey, carcasses, lymph nodes, abattoirs, disease surveys, disease prevalence, Mycobacterium tuberculosis, Brazil.

De Souza, A.V.; Antunes-e-Souza, C.F.; de Souza, R.M.; Ribeiro, R.M.P.; de Ligouri-Oliveira, A. A importancia da tuberculose bovina como zoonose. [The importance of bovine tuberculosis as a zoonosis].  Higiene Alimentar. 1999. 13 (59) 22-27. Note:  In Portuguese with an English summary.
Descriptors:  cattle, humans, Mycobacterium bovis, zoonoses, tuberculosis, epidemiology, skin testing, disease transmission, disease prevalence, diagnosis.

Denny, G.O.; Wilesmith, J.W. Bovine tuberculosis in Northern Ireland: a case-control study of herd risk factors.  Veterinary Record.  Mar 20, 1999. 144 (12) 305-310. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, badgers, Meles meles, tuberculosis, herd health, risk factors, epidemiology, boundaries, disease transmission, Mycobacterium bovis, Northern Ireland.

Diaz, F.; Masso, F.; Paez, A.; Varela, E.; Suarez-Guemes, F.; Montano, L.F. Secretion of IFN-gamma by bovine peripheral blood mononuclear cells stimulated with Mycobacterium bovis protein fractions obtained by isoelectric-focusing. Veterinary Immunology and Immunopathology.  Feb 22, 1999. 67 (3) 203-212. ISSN: 0165-2427
NAL Call Number:  SF757.2.V38
Abstract:  Due to the complexity and variety of biological effects found in Mycobacterium bovis (M. bovis) proteins analyzed solely on a molecular weight (MW) basis, we approached the purification of M. bovis proteins through their isoelectric point (pI). Twenty M. bovis culture filtrate protein extract (CFPE) isoelectric focused (IEF) protein fractions, confined between pI 3 and 10, were isolated. The MW of the major proteins isolated in the various fractions correlated with protein already reported 14-, 18-, 20-, 25-, 31-, 38-, 45-, 64-, 67- and 70 kDa by SDS-PAGE. Since several different pI fractions showed proteins of the same MW we tested the ability of all IEF fractions to stimulate interferon-gamma (IFN-gamma) production by peripheral blood mononuclear cells (PBMC) isolated from cattle with well defined M. bovis tuberculosis (TB) infection. In animals with few lesions IFN-gamma inductive IEF fractions were in the acid range. As the number of lesions increased, neutral fractions were also inductive. Some fractions with relatively few proteins induced as much IFN-gamma production as others with abundant proteins. None of the 20 IEF fractions enhanced IFN-gamma production by anergic cells. We conclude that IFN-gamma production in diseased animals is induced mainly by acidic mycobacterial proteins and that the response towards these proteins is enhanced as the disease progresses, what coincides with higher PPD reactivity. However, the IFN-gamma production in anergic status was severely affected. We found that this cytokine production is spontaneous and antigen-independent.
Descriptors:  cattle, Mycobacterium bovis, interferon, secretion, monocytes, bacterial proteins, fractionation, molecular weight, isoelectric point, lesions, biosynthesis, acidity.

Dvorska, L.; Havelkova, M.; Bartos, M.; Bartl, J.; Pavlik, I. Inzercni sekvence u mykobakterii a jejich vyuziti pri studiu epidemiologie mykobakterialnich infekci. [Insertion sequences of mycobacteria and their use in the study of the epidemiology of mycobacterial infections.] Veterinarni Medicina. 1999. 44 (8) 233-251. Note:  In Czech with an English summary.
NAL Call Number:  41.9 C333
Descriptors:  epidemiology, Mycobacterium avium ssp. paratuberculosis, Mycobacterium avium, Mycobacterium tuberculosis, Mycobacterium bovis, mycobacterial diseases, transposable elements of DNA.

Emmerzaal, A.; van Zijderveld, F.G.; Bakker, D. Het belang van een goede diagnostiek voor rundertuberculose. [The importance of a good diagnostic technique for bovine tuberculosis.] Tijdschrift voor Diergeneeskunde. 1999. 124 (24) 741-750. Note:  In Dutch.
NAL Call Number:  SF601 N4
Descriptors: 
Mycobacterium bovis, diagnostic techniques, tuberculin reaction, ELISA and gamma-interferon test, tuberculosis free status, Netherlands, EU.

Gonzalez-Llamazares, O.R.; Gutierrez-Martin, C.B.; Aranaz-Martin, A.; Liebana-Criado, E.; Dominguez-Rodriguez, L.; Rodriguez-Ferri, E.F. Comparison of different methods for diagnosis of bovine tuberculosis from tuberculin- or interferon-gamma-reacting cattle in Spain.  Journal of Applied Microbiology. Oct 1999. 87 (4) 465-471. ISSN: 1364-5072
NAL Call Number:  QR1.J687
Abstract:  Of 1479 cattle from herds in Northwestern Spain previously diagnosed as tuberculosis (TB) positive, 218 animals which gave a positive tuberculin or interferon-gamma reaction were examined at the slaughterhouse. Medial retropharyngeal and caudal mediastinal lymph nodes, and any tissues containing lesions suspected to be tuberculous, were removed and submitted to the laboratory. Three techniques for diagnosis of TB were used:  post mortem examination (PME), smear staining by means of auramine O method (AOM), and culture isolation in Coletsos and Lowenstein-Jensen media followed by confirmation of M. tuberculosis complex organisms using PCR (CIM-PCR). Only 123 (29.9%) of the 412 samples collected showed typical tuberculous lesions. Confirmed M. tuberculosis complex organisms were isolated in 144 cases, 114 of which were from tissues showing lesions (success rate of 92.8%). Smears were found positive in 113 cases, 96 of which came from lesions suspected to be tuberculous (success rate of 78.0%). The sensitivities of CIM-PCR compared with those of PME and AOM were 92.7% and 85.7%, respectively. Statistical analysis revealed that PME and AOM are good indicators of the presence of M. tuberculosis complex organisms in tuberculin-or interferon-gamma reacting cattle.
Descriptors:
  Mycobacterium tuberculosis, cattle, disease incidence, post-slaughter, Spain.

Gonzalez-Llamazares, O.R.; Gutierrez-Martin, C.B.; Alvarez-Nistal, D.; De la Puente-Redondo, V.A.; Dominguez-Rodriguez, L.; Rodriguez-Ferri, E.F. Field evaluation of the single intradermal cervical tuberculin test and the interferon-gamma assay for detection and eradication of bovine tuberculosis in Spain. Veterinary Microbiology. Oct 1999. 70 (1/2) 55-66. ISSN: 0378-1135
NAL Call Number:  SF601.V44
Abstract:  A field comparison of the interferon-gamma (IFN-gamma) assay and the single intradermal cervical tuberculin (SICT) test for the diagnosis of bovine tuberculosis was conducted. A total of 1136 cattle belonging to 85 herds placed in 'Castilla y Leon' (northwestern Spain) were chosen, and 21 of these herds were subjected to the diagnostic assays two or three times at intervals of at least 4 months. All the animals positive to any of the tests were slaughtered and tuberculosis was confirmed by culture isolation method (CIM) and further identification by means of PCR. Only 10.6% of cattle reacted with the bovine PPD in the SICT test, a percentage that increased to 12.8% in the IFN-gamma assay. The sensitivity of the IFN-gamma assay compared to CIM was shown to be higher (84.9%) than that of the SICT test (80.2%), but the combination of both tests offered the highest sensitivity (92.9%). The number of false positive reactors (those animals in which CIM was negative) was considerably higher for the IFN-gamma assay than for the SICT test and, conversely, the number of false negative animals (M. bovis isolation but negative immunological result) was higher for the skin test than for the interferon assay. In the herds tested twice, tuberculosis was eradicated after the second cycle of testing in 50%, and in 75% after the third cycle in herds tested three times. The combination of these two techniques instead of separately seems, therefore, to be useful in eradication programmes against bovine tuberculosis.
Descriptors:  cattle, Mycobacterium bovis, detection, diagnosis, field tests, tuberculin, interferon, disease control, incidence, disease prevalence, tuberculosis, skin tests, diagnostic value, Spain.

Gutierrez, M.; Garcia-Marin, J.F. Cryptococcus neoformans and Mycobacterium bovis causing granulomatous pneumonia in a goat. Veterinary Pathology. 1999. 36 (5) 445-448. ISSN: 0300-9858
NAL Call Number:  41.8 P27
Descriptors:  goat, Blanca-Celtiberica doe, case study, mixed infection, Cryptococcus neroformans, Mycobacterium bovis, pulmonary focal caseous nodules, pneumonia, impared immune status.

Hancox, M. A critical reappraisal of transmission routes for bovine TB in cattle.  Respiratory Medicine. 1999. 93 (3) 220-223.
Descriptors:  cattle, badgers, Mycobacterium, tuberculosis, disease control, epidemiology, zoonoses, disease transmission, wildlife disease reservoirs, UK.

Hancox, M.  Transmission of bovine TB in cattle: a critical reappraisal.  Letters in Applied Microbiology.  March 1999. 28 (3) 242-244. ISSN: 0266-8254
NAL Call Number:  QR1.L47
Descriptors:  tuberculosis, disease transmission, letters correspondence.

Hardjoutomo, S. Tuberkulosis sapi dan peranannya bagi peternakan sapi di Indonesia. [Bovine tuberculosis and its role in cattle farming in Indonesia.]  Journal Penelitian and Pengembangan Pertanian. 1999. 18 (2) 63-67. Note:  In Indonesian with an English summary.
Descriptors:
  Mycobacterium bovis, tuberculosis, beef cattle, dairy cattle, tuberculin, zoonoses, diagnosis, disease prevention.

Hutchings, M.R.; Harris, S. Quantifying the risks of TB infection to cattle posed by badger excreta. Epidemiology and Infection. 1999. 122 (1) 167-174.
NAL Call Number:  RA651 A1E74
Descriptors:  cattle, wild badgers, Meles meles, deterministic approach, grazing contact with excreta, investigatory contact with excreta, muzzle to sward contact, infection probability, Mycobacterium bovis, England, transmission levels, risk assessment.

Joardar, S.N.; Ram, G.C. Effect of fractionated antigens of Mycobacterium bovis AN5 on blood mononuclear cells of cattle. Indian Journal of Animal Sciences. 1999. 69 (1) 7-11.
NAL Call Number:  41.8 IN22
Descriptors:  cattle mononuclear blood cells, Mycobacterium bovis antigen AN5, immunogenetics, in vitro methods, lymphocyte transformation, tuberculosis, diagnosis, lymphocproliferation and nitrite production, bacterial diseases.

Jorge, M.C.; Schettino, D.M.; Egoburu, F.; Vaninetti, R.; Schang, E.; Gonzalez, H. Evaluacion del uso de la prueba tuberculinica en rodeos de cria y tambo - 1995/96. [Evaluation of the tuberculin skin test for use in dairy and beef herds - 1995/96.] Veterinaria Argentina. 1999. 16 (151) 8-14. Note:  In Spanish with an English summary.
NAL Call Number:  SF604 V463w/yak pro
Descriptors:  dairy and beef herds; tuberculin skin tests, diagnosis of tuberculosis, Mycobacterium bovis, Argentina.

Kanameda, M.; Ekgatat, M.; Wongkasemjit, S.; Sirivan, C.; Pachimasiri, T.; Kongkrong, C.; Buchaphan, K.; Boontarat, B. An evaluation of tuberculin skin tests used to diagnose tuberculosis in swamp buffaloes (Bubalus bubalis).  Preventive Veterinary Medicine.  Mar 29, 1999.  39 (2) 129-135. ISSN: 0167-5877.  Note:  Paper presented at the VIII International Symposium on Veterinary Epidemiology and Economics, July 8-11, 1997. Paris, France.
NAL Call Number:  SF601.P7
Descriptors:  buffaloes, tuberculin skin tests, diagnostic techniques, tuberculosis, evaluation, diagnosis, postmortem examinations, herd health monitoring, Mycobacterium bovis, diagnostic value, caudal fold skin tests, cervival skin test, stormont skin test.

Kao, R.R.; Roberts, M.G. A comparison of wildlife control and cattle vaccination as methods for the control of bovine tuberculosis. Epidemiology and Infection. 1999. 122 (3) 505-519.
NAL Call Number:  RA651 A1E74
Descriptors:
  Mycobacterium bovis, cattle, possums, Trichosurus vulpecula, cost of putative Tb, eradication, possum culling, vaccination of cattle or possums, compared, 1080 poison bait, wild animal disease reservoirs, epidemiology, mathematical models, New Zealand.

Kean, J.M.; Barlow, N.D.; Hickling, G.J. Evaluating potential sources of bovine tuberculosis infection in a New Zealand cattle herd. New Zealand Journal of Agricultural Research. 1999. 42 (1) 101-106.
NAL Call Number:  23 N4892
Descriptors:  cattle, disease control, epidemiology, Mycobacterium bovis, tuberculosis, disease transmission, wild animals as disease reservoirs, brushtail possum, Trichosurus vulpecula, New Zealand.

Kostov, G.; Bachvarova, Y.; Stephanov, M.; Arnaoudov, A. Occurrence of antibodies against Actinomyces pyogenes in blood sera from cattle showing non-specific tuberculin reactions. Bulgarian Journal of Veterinary Medicine. 1999. 2 (1) 41-45.
Descriptors:  tuberculin skin tests, non-specific tuberculin reactions, agglutination, agglutinins, antigens, diagnosis, tuberculosis, diagnostic techniques, blood serum samples, bacterial diseases, Actinomyces, Arcanobacterium pyogenes, cattle, Mycobacterium bovis, Mycobacterium avium.

Kumar, G.S.N.; Govindiah, M.G.; Nagaraj, C.S.; Bindu, A.; Rasool, T.J. Does the natural resistance associated macrophage protein (Nramp) gene confer resistance/susceptibility in bovines against mycobacterial infection? Current Science. 1999. 77 (6) 809-812.
NAL Call Number:  475 Sci23
Descriptors:  mycobacterial infection, mice, BCG locus contains natural resistance, macrophage protein gene, point mutations, resistance and susceptibility, TB, search for similarity in bovine genome, Mycobacterium, cattle resistance factors.

Lazovskaya, A.L.; Vorob'eva Z.G.; Slinina, K.N.; Ispolatov, V.A. Diagnosis of horned cattle tuberculosis with the use of the microsphere test.  [Russian Agricultural Sciences.] 1999. No. 4, 45-49; Doklady Rossiiskoi Akademii Sel'skokhozyaistvennykh Nauk. 1999. No. 4.
NAL Call Number:  S1 S68
Descriptors:  latex agglutination test, specificity, sensitivity, diagnostic value, cattle tuberculosis, Mycobacterium bovis, antibodies.

Liebana, E.; Girvin, R.M.; Welsh, M.; Neill, S.D.; Pollock, J.M. Generation of CD8+ T-cell responses to Mycobacterium bovis and mycobacterial antigen in experimental bovine tuberculosis.  Infection and Immunity.  1999. 67 (3) 1034-1044. ISSN: 0165-2427
NAL Call Number:  SF57.2.V38
Descriptors:  cattle, tuberculosis, Mycobacterium, immune response, in vitro activation of CD 8+ T lymphocytes, antigens, surface antigens, lymphocyte antigens, experimental infections, immune response, PPDb, proliferative responses, peripheral blood mononuclear cells, gamma interferon, brefeldin A, cytochalasin D.

Lilenbaum, W.; Schettini, J.C.; Souza, G.N.; Ribeiro, E.R.; Moreira, E.C.; Fonseca, L.S. Comparison between a gamma-IFN assay and intradermal tuberculin test for the diagnosis of bovine tuberculosis in field trials in Brazil. Journal of Veterinary Medicine, Series B.  June 1999. 46 (5) 353-358. ISSN: 0931-1793
NAL Call Number:  41.8 Z52
Descriptors:  dairy cattle, Mycobacterium bovis, bioassays, interferon, diagnosis, field experimentation, diagnostic techniques, immunodiagnosis, evaluation, tuberculin, risk assessment, Rio de Janeiro, Brazil.

Lilenbaum, W.; Ribeiro, E.R.; Souza, G.N.; Moreira, E.C.; Fonseca, L.S.; Ferreira, M.A.S.; Schettini, J. Evaluation of an ELISA-PPD for the diagnosis of bovine tuberculosis in field trials in Brazil.  Research in Veterinary Science.  June 1999. 66 (3) 191-195. ISSN: 0034-5288
NAL Call Number:  41.8 R312
Abstract:  Bovine tuberculosis is a major health problem in Brazil. The intradermal tuberculin test is the standard test for its detection but it can lack both sensitivity and specificity. The purpose of this study was to evaluate a bovine enzyme-linked immunosorbent assay-(ELISA-ppd) under field conditions in Brazil. A total of 1632 animals from 13 dairy farms were tested with the intradermal tuberculin test (ITT). Two hundred and seven cows gave a positive reaction, which represents 12(.)7 per cent of the cattle studied. The sensitivity specificity rates to ITT were 87(.)7 per cent and 95(.)2 per cent, respectively. From the 1632 animals 15 per cent of each herd (220 in total) were selected to be tested by the ELISA. Differences between mean optical density (OD) of the control group, ITT-positive and ITT-negative groups were all significant (P<0(.)01). The sensitivity rates to ELISA-PPD were 86(.)7 percent, while specificity was 90(.)6 per cent. The use of ELISA-PPD is suggested for situations where the investigation of the whole herd is more important than the individual testing of each cow. In addition, the ELISA-PPD can also be helpful when a collective diagnosis is desired to elucidate clinical suspicions of disease, or in the first steps of a control program, for identification of foci.
Descriptors:  dairy cows, tuberculosis, Mycobacterium bovis, ELISA, diagnostic techniques, herds, diagnostic value, Brazil.

Lilenbaum, W. O uso de ELISA para o diagnostico da tuberculose bovina no Brasil: uma possibilidade interessante? [Use of ELISA for the diagnosis of bovine tuberculosis in Brazil: an interesting possibility?]  Revista Brasileira de Medicina Veterinaria. 1999. 21 (1) 28-31. Note:  In Portuguese with an English summary.
NAL Call Number:  SF604 R38
Descriptors:  cattle, ELISA, diagnosis, Mycobacterium bovis, tuberculosis, Brazil.

Lis, H.  Ocena wynikow badania sanitarno-weterynaryjnego zwierzat rzeznych i miesa w Polsce w latach 1987-1997. [An evaluation of veterinary inspection of slaughtered animals and meat in Poland between 1987 and 1997.]  Medycyna Weterynaryjna. 1999. 55 (4) 243-246. Note:  In Polish with an English summary.
NAL Call Number:  41.8 M463
Descriptors:  sheep, horses, liver flukes, Fasciola, Taenia, trichinosis, meat inspection, meat quality, cattle, pigs, calves, post slaughter examination, lesions carcasses, tuberculosis, septicaemia, neoplasms, leukemia, jaundice, emaciation, disease prevalence, muscular diseases, parasites, helminthes, Poland.

Longeri, M.; del Bo, L.; Vercelloni, L.; Amadori, M.; Archetti, I.L.; Zanotti, M. BoLA DRB3 exon 2 polymorphism in tuberculosis infected cattleArchiv fur Tierzucht. 1999. 42 (Special issue) p. 100-102. International Symposium: Candidate Genes for Animal Health, Rostock Warnemunde, Germany, 25-27 August, 1999. Note:  Symposium proceedings.  In English with a German summary.
NAL Call Number:  49 AR23
Descriptors:  tuberculosis, disease progress, polymorphism, interferon, alleles, antigens, Friesian cattle, disease resistance; RFLP, bacterial diseases, Mycobacterium, genetic effect on gamma IFN secretion, bovine lymphocyte antigen.

Melo, L.E.H.de; D' Angelino, J.L.; Castro, R.S.de; Schalch, U.M.; Pacheco, J.C.G.; Benatti, L.A.T.; Araujo, W.P.de; Pinheiro, S.R.  Prevalencia de vacas reagentes a tuberculinizacao simultanea em rebanhos produtores de leite do tipo C do Estado de Sao Paulo.  [Prevalence of reactor cows to simultaneous tuberculin test in dairy herds from the State of Sao Paulo.]  Ciencia Veterinaria nos Tropicos.  1999; 2(2): 91-99.  ISSN:  1415-6326.  Note:  In Portuguese with an English summary.  
Descriptors:  bovine tuberculosis, Mycobacterium bovis, Zebu x Holstein cows, 21 dairy herds, intradermal testing, wide spread disease prevalence, Sao Paulo, Brazil.

Meyer, Robert M. Erradicacion de la Tuberculosis Bovina: Seminario deAactualizacion para Medicos Veterinarios. [Eradication of  Bovine Tuberculosis: Seminar of Response by Veterinarians.] [United States?], 1999. 50, [16] p.  Note:  In Spanish with an English summary.
NAL Call Number:  SF967.T8M4918 1999
Descriptors:  tuberculosis, cattle, seminar, veterinary medicine, Mycobacterium. 

Moka, G.; Berxholi, K.; Panariti, E.; Malaj, Z.; Biba, N.; Cabeli, P. Metodi per la diagnosi di TBC bovina. [New methods for the diagnosis of bovine tuberculosis.] Selezione Veterinaria. 1999. No. 10, 743-749. Note:  In Italian with an English summary.
NAL Call Number:  241.71 B75
Descriptors:  bovine tuberculosis, Mycobacterium bovis, cattle, gamma IFN test, diagnosis, test sensitivity, disease prevention and eradication, lesions.

Monies, R.J.; Head, J.C.S. Bovine tuberculosis in housed calves. Veterinary Record. 1999. 145 (25) 743. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  bovine tuberculosis, TB, dairy calves, lung lesions, infected cow, transmission, infected milk, etiology, Mycobacterium bovis, intercurrent bovine diarrhea virus, dairy farm, UK.

Montgomery, R.H. Mycobacteria in New Zealand. Surveillance. 1999. 2 (1) 6-8; 18.
NAL Call Number:  SF604.63 N45S87
Descriptors:   birds, possums, dogs, cats, rabbits, pigs, sheep, goats, deer, cattle, humans, Mycobacterium taxonomy, diagnosis, disease transmission, disease prevalence, disease control, Mycobacterium bovis, Mycobacterium tuberculosis, Erinaceidae, Mustela erminea, Mycobacterium avium, Mycobacterium paratuberculosis, Mycobacterium lepraemurium, Mycobacterium marinum, Mycobacterium kansasii, New Zealand.

Morales-Alvarez, F.  Using a multiplex PCR to differentiate between M. bovis BCG-vaccinated and pathogenic M. bovis-infected goats.  Tecnica Pecuaria en Mexico.  2004; 42 (3): 419-428.  ISSN:  0040-1889.  Note:  In English and Spanish.  
NAL Call Number:  49 T222
Descriptors:  goats, Mycobacterium bovis, multiplex PCR diagnostic tests, differentiating animals vaccinated with BCG and pathogenic Mycobacterium bovis infection, nasal mucus, blood and organ tissues, immune sensitization.

Munroe, F.A.; Dohoo, I.R.; Goodall, E.A. (ed.); Thursfield, M.V. Estimating the incidence rate of within-herd spread of M.[Mycobacterium] bovis. Proceedings of a meeting held at the University of Bristol, UK, on the 24-26th March, 1999. UK. Roslin, Society for Veterinary Epidemiology and Preventive Medicine 1999. p. 164-171.
Descriptors: 
Mycobacterium, humans, cattle herds, Cervidae, epidemiology, disease prevention, tuberculosis, disease transmission, zoonoses, disease surveys, outbreaks, sex, breeds, age, methodology, disease models, risk factors; disease prevalence, Canada.

Munroe, F.A.; Dohoo, I.R.; McNab, W.B.; Spangler, L. Risk factors for the between-herd spread of Mycobacterium bovis in Canadian cattle and cervids between 1985 and 1994.  Preventive Veterinary Medicine. 1999. 41 (2-3) 119-133.
NAL Call Number:  SF601 P7
Descriptors:  cattle, cervids, tuberculosis outbreaks, Mycobacterium bovis, positive or negative herd analysis, outbreak records, logistic regression, spread of tuberculosis between herds, herd size, disease transmission, statistical analysis, Canada.

Neumann, G.B. Bovine tuberculosis--an increasingly rare event.  Australian Veterinary Journal.  July 1999.  77 (7) 445-446.  ISSN: 0005-0423
NAL  call number:  41.8 Au72
Descriptors:  cattle, tuberculosis, Mycobacterium bovis, disease control, control programs, disease surveys, Australia.

Palmer, M.V.; Whipple, D.L.; Rhyan, J.C.; Bolin, C.A.; Saari, D.A.  Granuloma development in cattle after intratonsilar inoculation with Mycobacterium bovis. American Journal of Veterinary Research.  1999. 60 (3) 310-315. ISSN: 0002-9645
NAL Call Number:  41.8 Am3A
Descriptors:  crossbred cattle, cows, tuberculous lesions, temporal development, experimental infection, Mycobacterium bovis, intra-tonsilar injection, pathogenesis, fibrosis, giant cells, necrosis, granulomas, lymph nodes, lymphocytes, macrophages, neutrophils, plasma cells.

Pavlik, I.; Bartl, J.; Franta, V.; Matlova, L.; Dvorska, L.; Ayele, W.Y.; Bures, F.; Smolik, J.; Kostka, F. Vyznam prikrmovani raseliny pri tvorbe tuberkuloznich zmen v miznich uzlinach prasat. [The role of peat in the development of tuberculous lesions in porcine lymph nodes.] Veterinarstvi. 1999. 49 (11) 466-468. Note:  In Czech with an English summary.
NAL Call Number:  41.8 V6439
Descriptors:  pigs, Mycobacterium, Mycobacterium intracellulare, tuberculosis, peat litter, disease transmission, meat inspection, lymph nodes, Czech Republic.

Perumaalla, V.S.; Adams, L.G.; Payeur, J.; Baca, D.; Ficht, T.A.  Molecular fingerprinting confirms extensive cow-to-cow intra-herd transmission of a single Mycobacterium bovis strain. Veterinary Microbiology. Dec 1999. 70 (3/4) 269-276. ISSN: 0378-1135
NAL Call Number:  SF601.V44
Abstract:  In this study we have characterized M. bovis isolates from a herd of cattle in Uvalde, Texas in which 52 of the 193 animals selected at random in 1994 from a herd of 331 were caudal fold skin-test positive. Thirty-two of 52 skin-test positive cattle had gross lesions at slaughter, and isolations of M. bovis were made from 29 animals. The herd was comprised of Red Devon cattle purchased between 1978 and 1980 (n = 26) and breeding bulls (n = 3) introduced at later times, and all were tuberculosis test negative at the time of purchase. Other animals were natural additions (offspring) of these cattle. One additional animal, a Holstein present on the ranch at the time of purchase in 1976, was retained to nurse orphaned and weak calves. Using several molecular fingerprinting techniques we have verified a clonal relationship among the M. bovis isolates consistent with infection originating with a single strain. The molecular fingerprint patterns demonstrate the stability of the profiles despite persistence and spread of the organism within the herd for two decades and confirms their use in epidemiological tracing.
Descriptors:  Red Devon cattle, Mycobacterium bovis, disease transmission, herds, DNA fingerprinting, chemical composition, tuberculosis, bacterial diseases, strain differences, skin testing, single strain, lesions, persistence, bulls, epidemiology, Texas.

Pinheiro, S.R. Controle da tuberculose bovina versus tratamento. [Control of bovine tuberculosis versus treatment.] O Biologico. 1999. 61 (2) 139-142. Note:  In Portuguese.
Descriptors:  cattle diseases, disease control, tuberculosis, cattle.

Rogers, L.M.; Delahay, R.J.; Cheeseman, C.L.; Smith, G.C.; Clifton-Hadley, R.S. The increase in badger (Meles meles) density at Woodchester Park, south-west England: a review of the implications for disease (Mycobacterium bovis) prevalence.  Mammalia. 1999. 63 (2) 183-192. Note:  In English with a French summary.
NAL Call Number:  410 M31
Descriptors:  ecology, wild animals, intermediate hosts, disease reservoirs, disease prevalence, tuberculosis, Mycobacterium bovis, badgers, cattle, England, UK.

Romano, M.I.; Alito, A.; Zumarraga, M.J.; Bigi, F.; Cataldi, A.  Uso de sondas moleculares para la epidemiologia de la tuberculosis bovina. [Use of molecular probes for epidemiological studies of bovine tuberculosis.]  Revista Argentina de Microbiologia. 1999. 31 (Suppl. 1) 1-3. Note:  Segundo taller internacional sobre infecciones humanas y animales producidas por chlamidias, micobacterias, brucelas y borrelias. Buenos Aires, 25 junio-4 julio 1997. In Spanish.
Descriptors:  epidemiology, infections, Mycobacterium tuberculosis, mycobacterial diseases, DNA probes, cattle diseases.

Schettino, D.M.; Jorge, M.C.; Torres, P. Tendencia de la situacion sanitaria de la tuberculosis en rodeos bovinos. Argentina, 1998. [Status of the sanitary situation regarding tuberculosis in cattle. Argentina, 1998.]  Veterinaria Argentina. 1999. 16 (156) 427-433. Note:  In Spanish with an English summary.
NAL Call Number:  SF604 V463
Descriptors:  beef cattle, dairy cattle, prevalence, tuberculosis, PPD tuberculin, bacterial antigens, epidemiological surveys, Mycobacterium, Argentina.

Serraino, A.; Marchetti, G.; Sanguinetti, V.; Rossi, M.C.; Zanoni, R.G.; Catozzi, L.; Bandera, A.; Dini, W.; Mignone, W.; Franzetti, F.  Monitoring of transmission of tuberculosis between wild boars and cattle: genotypical analysis of strains by molecular epidemiology techniques.  Journal of Clinical Microbiology. Sept 1999.  37 (9) 2766-2771. ISSN: 0095-1137
NAL Call Number:  QR46.J6
Descriptors:  cattle, wild boars, Mycobacterium bovis, DNA fingerprinting, restriction fragment length polymorphism, RFLP, disease transmission, Liguria.

Shamoon, G.N. Isolation and diagnosis of mycobacteria species in ewes suffering from mastitis in Nineveh province.  Iraqi Journal of Veterinary Sciences. 1999. 12 (2) Ar97-Ar99. Note:  In Arabic with an English summary.
Descriptors:  diagnosis, sheep, ewes, mastitis, ewe milk, Mycobacterium strains, tuberculosis, disease surveys, Mycobacterium avium complex, Mycobacterium bovis, Iraq.

Silva, E.; Merlini, J.C.; de Kantor, I.N.; Bernardelli, A.; Robinson, A.; Nibot, C.; Gonzalez, N.; Regalado, L.; Alfonso, M.J.; Martinez, N. Evaluacion de la tecnica de ELISA (sistema DAVIH-TBB) para el diagnostico de la tuberculosis bovina. [Evaluation of the ELISA technique (DAVIH-TBB system) for the diagnosis of bovine tuberculosis.]  Revista de Medicina Veterinaria, Buenos Aires. 1999. 80 (5) 361-363. Note:  In Spanish with an English summary.
NAL Call Number:  41.8 B86
Descriptors:
  Mycobacterium bovis, tuberculosis, cattle, serum sampling, ELISA test, diagnostic techniques, lesions, purified protein derivative test, tuberculin, disease detection, herds, Cuba.

Silvestri, A. La tubercolosi bovina tra inizio e fine secolo. [Tuberculosis in livestock in the twentieth century.] Atti della Societa Italiana di Buiatria. 1999. 31: 79-89. Congresso Nazionale, Marina di Ragusa, Italy, June 1999. Note:  In Italian with an English summary.
Descriptors:  cattle tuberculosis, Mycobacterium, zoonotic diseases, diagnosis and treatment, prophylaxis, sanitation, hygiene, animal health.

Slobbe, L.; Lockhart, E.; O'Donnell, M.A.; Mackintosh, C.; de Lisle, G.; Buchan, G.  An in vivo comparison of bacillus Calmette-Guerin (BCG) and cytokine-secreting BCG vaccines [in red deer]. Immunology. 1999. 96 (4) 517-523.
NAL Call Number:  448.3 IM6
Descriptors:  red deer, immunized, BCG (Pasteur 1173 P2 strain, recombinant BCG (rBCG/IL-2), immune responses, vaccines, introdermal skin test responses to BCG antigens, lymphocyte transformation, shuttle plasmid, Mycobacterium bovis, Mycobacterium bovis BCG strain.

Suppiger, F. Die Tierseuchenbekampfung in der Schweiz von 1896 bis 1996, insbesondere im Kanton Luzern. [Control of animal epidemic diseases in Switzerland between 1896 and 1996 with particular emphasis on the situation in the Canton of Lucerne.] Schweizer Archiv fur Tierheilkunde. 1999. 141 (1) 11-20. Note:  In German.
NAL Call Number:  41.8 SCH9
Descriptors:  horses, pigs, cattle, disease prevention and control, domestic animals, infectious diseases, bacterial diseases, tuberculosis, brucellosis, bovine leucosis, swine fever, veterinary history, BSE, bovine spongiform encephalopathy, Mycobacterium, Switzerland.

Sutmoller, P.  Risk of disease transmission by llama embryos.  Revue Scientifique et Technique  Office International des Epizooties. 1999. 18 (3) 719-728. Note:  In English with French and Spanish summaries.
NAL Call Number:  SF781 R4
Descriptors:  disease transmission risks, embryos, brucellosis, contamination, embryo transfer, FMD, risk assessment, tuberculosis, zona pellucida, arboviruses, bacterial diseases, viral diseases, Bluetongue virus, Brucella, Mycobacterium, vesicular stomatitis virus, llamas.

Tonoli, N. Tubercolosi nel suino: esperienza in un macello industriale della Lombardia. [Tuberculosis in pigs: experience in an industrial abattoir in Lombardy.]  Praxis Veterinaria Milano. 1999. 20 (3) 11-14. Note:  In Italian with an English summary.
Descriptors:  pigs, Mycobacterium avium, lesions, liver, lungs, lymph nodes, pleura, spleen, mycobacterial diseases, postmortem examinations, symptoms, swine diseases, Italy.

UK, British Small Animal Veterinary Association Scientific Committee. Scientific information document: tuberculosis. Journal of Small Animal Practice. 1999. 40 (3) 145-147.
NAL Call Number:  41.8 J8292
Descriptors:  cattle, reptiles, fishes, amphibians, humans, cats, dogs, Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium avium, tuberculosis, zoonoses, pathogenesis, treatment, diagnosis, radiography, histopathology, reviews.

Vela, A.I.; las Heras, A.; de Juan, L.; Aranaz, A.; Mateos, A.; Dominguez, L.; de Juan, L. El problema de erradicar la tuberculosis bovina. [The problem of eradicating bovine tuberculosis.]  Mundo Ganadero. 1999. 10 (115) 48, 50, 52, 54-55. Note:  In Spanish.
Descriptors:  Mycobacterium bovis, epidemiology, diagnosis, control, disease control, livestock, tuberculosis, current disease levels, Spain.

Vetesi, F. A sertes legzoszervi betegsegei Patologiai vonatkozasok. [Pathological aspects of selected swine respiratory disorders.] Magyar Allatorvosok Lapja. 1999. 121 (8) 467-475. Note:  In Hungarian with an English summary.
NAL Call Number:  41.8 V644
Descriptors:  pigs, various diseases including tuberculosis, pathogenesis, physiopathology, mixed infections, immune responses, immune systems, lungs, bacterial diseases, parasitic diseases, pasterurellosis, viruses.

Vordermeier, H.M.; Cockle, P.C.; Whelan, A.; Rhodes, S.; Palmer, N.; Bakker, D.; Hewinson, R.G. Development of diagnostic reagents to differentiate between Mycobacterium bovis BCG vaccination and M. bovis infection in cattle. Clinical and Diagnostic Laboratory Immunology. 1999. 6 (5) 675-682.
Descriptors:  recombinant forms of antigens, BCG Pasteur (ESAT-6, MPB64, MPB70, MPB83), testing, Mycobacterium bovis, calf mononuclear cells, sensitized animals, M. bovis infected, BCG vaccinated, M. avium sensitized, in vitro proliferation and gamma interferon responses, peptide and protein cocktails formulations, T cell epitopes.

Webber, W. (ed.); Budge, G . Proceedings of the 29th Seminar of the Society of Sheep and Beef Cattle Veterinarians NZVA, 1-3 March 1999, Angus Inn Hotel, Hastings, New Zealand. Publication - Veterinary Continuing Education, Massey University. 1999. No. 189, vi and 186 pp. Note:  A conference proceeding of 32 papers, sheep and cattle, a variety of diseases and deficiencies, toxicities, tuberculosis testing, meat safety.
NAL Call Number:  SF604 P82
Descriptors:  beef cattle, sheep, public health, veterinarians, abortion, poisonous plants, deficiency diseases, vitamin B12, cobalt, public health, meat quality, meat hygiene, nitrates, fertilizers, zoonotic diseases, calcium and magnesium levels, tuberculosis, Mycobacterium, Salmonella, Bacillus, Campylobacter, Neospora, New Zealand.

Wedlock, D.N.; Aldwell, F.E.; Collins, D.M.; de Lisle, G.W.; Wilson, T.; Buddle, B.M. Immune responses induced in cattle by virulent and attenuated Mycobacterium bovis strains: correlation of delayed-type hypersensitivity with ability of strains to grow in macrophages. Infection and Immunity.  May 1999. 67 (5) 2172-2177. ISSN: 0019-9567
NAL Call Number:  QR1.I57
Abstract:  Comparison of immune responses induced in cattle by virulent and attenuated strains of Mycobacterium bovis will assist in identifying responses associated with resistance or susceptibility to disease. Four strains of M. bovis, one which is virulent in guinea pigs (WAg201) and three which are attenuated in guinea pigs (an isoniazid-resistant strain [WAg405], ATCC 35721, and BCG) were compared for their abilities to induce immune responses in cattle and to grow in bovine lung alveolar macrophage cultures. Extensive macroscopic lesions were found only in cattle inoculated with the virulent M. bovis strain. Strong antibody responses to M. bovis culture filtrate, as well as persistently high levels of gamma interferon and interleukin-2 released from purified protein derivative (PPD)-stimulated peripheral blood lymphocyte cultures, were observed in the cattle inoculated with the virulent strain compared to those inoculated with the attenuated strains. All cattle inoculated with the virulent strain or two of the attenuated strains (WAg405 and ATCC 35721) elicited strong delayed-type hypersensitivity responses to PPD in skin tests, while animals inoculated with BCG induced only a weak response. The three strains which produced strong skin test responses proliferated well in bovine alveolar macrophages and induced high levels of proinflammatory cytokine mRNAs compared to BCG. Our study showed that skin test responsiveness to PPD correlated with the ability of the strains to grow in alveolar macrophages rather than to their pathogenicity in cattle.
Descriptors:  tuberculosis, Mycobqacterium, antibody formation, interleukin 2, cattle, immune responses, strain responses, skin tests responsiveness to PPD, alveolar macrophages, pathogenicity in cattle.

Woodroffe, R.; Frost, S.D.W.; Clifton-Hadley, R.S. Attempts to control tuberculosis in cattle by removing infected badgers: constraints imposed by live test sensitivity. Journal of Applied Ecology. 1999. 36 (4) 494-501. 
NAL Call Number:  410 J828
Descriptors:  cattle, Mycobacterium bovis, tuberculosis, culling badgers, Meles meles, disease transmission, wildlife disease reservoirs, disease control, serology, immunodiagnosis, wild animals, control, identifying infected animals for removal, UK.


1998

Acosta, B.; Real, F.; Ferrer, O.; Deniz, S; Poveda, J.B.  Isolation of Mycobacterium kansasii from a tuberculin-positive goat.  Veterinary Record.  Feb 21, 1998.  142 (8) 195-196. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  goats, Mycobacterium kansasii, lymph nodes, isolation, lesions, tuberculosis, case reports.

Addo, K.K.; Kapitancik, B.; Velebny, S.; Hrckova, G.; Mattova. J.; Dubinsky, P. The experimental immunization of cattle against tuberculosis by liposomized BCG vaccine. Folia Veterinaria. 1998. 42 (3) 153-157.
NAL Call Number:  41.8 F712
Descriptors:  cattle, Mycobacterium bovis, Mycobacterium bovis BCG strain, tuberculosis, BCG vaccine, liposomes, immunization, live vaccines, experimental infection, calves.

Alves-Junior, M; dos Santos, P.C.G.; Paleari, J.P.; Russomano, M. Carcinoma de perolas corneas da regiao frontal de bovino associado a tuberculose pulmonar do tipo nodular multipla. [Frontal corneal carcinoma in a bull associated with multiple nodular type pulmonary tuberculosis.UNIMAR Ciencias. 1998. 7 (2) 189-192. Note:  In Portuguese with an English summary.
Descriptors:  case report, cattle, bull, cornea neoplasms, nodular-type pulmonary tuberculosis, Mycobacterium, Brazil.

Amadori, M.; Tameni, S.; Scaccaglia, P.; Cavirani, S.; Archetti, I.L.; Giandomenico, R.Q. Antibody tests for identification of Mycobacterium bovis-infected bovine herds. Journal of Clinical Microbiology. 1998. 36 (2) 566-568.
NAL Call Number:  QR46.J6
Descriptors:  cattle, ELISA, Mycobacterium bovis, tuberculosis, serum sampling, diagnosis, antibodies, ELISA, tuberculosis, Italy.

Anonomyous. A challenging task on TB. Veterinary Record.  Mar 14, 1998.  142 (11) 257. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:    tuberculosis, badgers, Meles meles, cattle, disease control.

Anonomyous. No quick fix on TB. Veterinary Record.  Jan 3, 1998.  142 (1) 1. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, tuberculosis, Mycobacterium bovis, badgers, Meles meles, disease control, UK.

Antognoli, M.C.; Pereira, J.J.; Rodriguez, F.; Garbaccio, S. Tuberculosis bovina en guachera. [Bovine tuberculosis on a dairy farm.]  Veterinaria Argentina. 1998. 15 (149) 631-636. Note:  In Spanish with an English summary.
NAL Call Number:  SF604 V463
Descriptors:  dairy farm, calves, intradermal testing, tuberculosis disease outbreak, disease transmission, Mycobacterium, feeding of unpasteurized milk, Argentina.

Atallah, S.T.; El Kak, A.A.  Economic loss due to infection of cattle and buffaloes with tuberculosis and brucellosis. Alexandria Journal of Agricultural Research. 1998. 43 (3) 367-376. Note:  In English with an Arabic summary.
NAL Call Number:  24 AL2
Descriptors:  Mycobacterium bovis, Brucella, tuberculosis, disease prevalence, carcass condemnation, breed differences in susceptibility, losses, crossbreds, buffalo, cattle breeds, economic losses, Egypt.

Barlow, N.D.; Kean, J.M.; Caldwell, N.P.; Ryan, T.J. Modelling the regional dynamics and management of bovine tuberculosis in New Zealand cattle herds. Preventive Veterinary Medicine. 1998. 36 (1) 25-38.
NAL Call Number:  SF601 P7
Descriptors:  tuberculosis, disease control, models, transport of animals, wild animals, disease transmission, statistical analysis, Mycobacterium bovis, cattle, Waikato region, herd-to-herd transmission, New Zealand.

Benet, J.J. Surveillance des evenements rares: la tuberculose bovine en France. [Surveillance of rare health events: example of bovine tuberculosis in France.Epidemiologie et Sante Animale. 1998. No. 34, 47-55. Note:  In French with an English summary.
Descriptors:  cattle, tuberculosis, skin tests, disease survey, risk factors, France.

Benkirane, A. Bovine tuberculosis in Africa. World Animal Review. 1998. No. 90, 54-56. Note in English with French and Spanish summaries.
NAL Call Number:  SF191 W6
Descriptors:  cattle, Mycobacterium tuberculosis, epidemiology, disease prevention and control, diagnosis, zoonoses, Africa.

Bisping, W.  Zur Geschichte der Bekampfung der Rindertuberculose - Beitrage aus dem Institut fur Mikrobiologie und Tierseuchen der Tierarztlichen Hochschule Hannover. [History of control measures against bovine tuberculosis - contributions from the Institute of Microbiology and Contagious Diseases, Veterinary School Hannover.]  Berliner und Munchener Tierarztliche Wochenschrift. 1998. 111 (10) 362-367. Note:  In German with an English summary.
NAL Call Number:  41.8 B45
Descriptors:  cattle, veterinary history, disease control, tuberculosis, Germany.

Bollo, E.; Guarda, F.; Capucchio, M.T.; Galietti, F. Direct detection of Mycobacterium tuberculosis complex and M. avium complex in tissue specimens from cattle through identification of specific rRNA sequences.  Journal of Veterinary Medicine. Series B.  Sept 1998. 45 (7) 395-400. ISSN: 0931-1793
NAL Call Number:  41.8 Z52
Descriptors:  cattle, Mycobacterium avium, Mycobacterium tuberculosis, detection, diagnostic techniques, diagnosis, ribosomal RNA, identification, evaluation, clinical aspects.

Brown, W.H.; de Anda, J.H. Tuberculosis in adult beef cattle of Mexican origin shipped direct-to-slaughter into Texas. Journal of the American Veterinary Medical Association.  Feb 15, 1998. 212 (4) 557-559. ISSN: 0003-1488
NAL Call Number:  41.8 Am3
Descriptors:  beef cattle, tuberculosis, Mycobacterium bovis, disease prevalence, geographical variation, exports, risk, disease control, Mexico, Texas.

Caley, P.; Spencer, N.J.; Cole, R.A.; Efford, M.G.  The effect of manipulating population density on the probability of den-sharing among common brushtail possums, and the implications for transmission of bovine tuberculosis. Wildlife Research. 1998. 25 (4) 383-392.
NAL Call Number:  S960 W5
Descriptors:  cattle, brushtail possums, Trichosurus vulpecula, population density, disease transmission, Mycobacterium bovis, tuberculosis, wild animals, populations, New Zealand.

Carpenter, E.; Fray, L.; Gormley, E. Antigen-specific lymphocytes enhance nitric oxide production in Mycobacterium bovis BCG-infected bovine macrophages.  Immunology and Cell Biology. 1998. 76 (4) 363-368. 
NAL Call Number:  QR180 I43
Descriptors:  cattle, immunization, nitric oxide, NO, macrophages, immunity, lymphocytes, interferon, cell mediated immunity, immune response, vaccination, Mycobacterium bovis, Mycobacterium bovis BCG, tuberculosis, recombinant bovine interferon (IFN)-gamma.

Cassidy, J.P.; Bryson, D.G.; Pollock, J.M.; Evans, R.T.; Forster, F.; Neill, S.D.  Early lesion formation in cattle experimentally infected with Mycobacterium bovis.  Journal of Comparative Pathology. 1998. 119 (1) 27-44. ISSN: 0021-9975
NAL Call Number:  41.8 J82
Descriptors:  cattle, Mycobacterium bovis, experimental infections, intranasal inoculation, respiratory tract lesions, retropharyngeal lymph nodes, caudal lung lobe, immunopathology, neutrophils, cell mediated immunity, tuberculosis.

Chaddock, H.M.  Northeast Michigan surveillance activities for bovine tuberculosis in the livestock and free-ranging deer populations. Proceedings One Hundred and Second Annual Meeting of the United States Animal Health Association, Minneapolis, Minnesota, USA, 3-9 October, 1998. United States Animal Health Association; Richmond; USA. 1998. p. 660-686.
NAL Call Number:  49.9 UN3R
Descriptors:  free-ranging deer, livestock, disease transmission, surveillance, tuberculosis, overcrowding effects, public health, food safety, wildlife as disease reservoirs, disease control, reviews, Michigan.

Converse, P.J.; Dannenberg, A.M. Jr.; Shigenaga, T.; McMurray, D.N.; Phalen, S.W.; Stanford, J.L.; Rook, G.A.W.; Koru-Sengul, T.; Abbey, H.; Estep, J.E.; Pitt, M.L.M. Pulmonary bovine-type tuberculosis in rabbits: bacillary virulence, inhaled dose effects, tuberculin sensitivity, and Mycobacterium vaccae immunotherapy. Clinical and Diagnostic Laboratory Immunology. 1998. 5 (6) 871-881.
Descriptors:
  Mycobacterium vaccae, rabbit pulmonary tuberculosis, immunology factors, virulence, effects, tuberculin, immunotherapy, live vaccines.

Costello, E.; Doherty, M.L.; Monaghan, M.L.; Quigley, F.C.; O'Reilly, P.F.  A study of cattle-to-cattle transmission of Mycobacterium bovis infection.  Veterinary Journal.  May 1998.  155 (3) 245-250. ISSN: 1090-0233
NAL Call Number:  SF601.V484
Abstract:  Twenty steers, positive to the single intradermal comparative tuberculin test (SICTT), were selected from herds with a recent history of Mycobacterium bovis infection. Ten steers, negative to SICTT, were selected from herds with no history of M. bovis infection and served as in-contact animals. The animals were divided into 10 groups, each consisting of two SICTT-positive (reactor) animals and one in-contact animal. Each group was housed in an individual loose-box for a period of 1 year. Five of the groups were fed a restricted diet for part of the experiment. All cattle were slaughtered at the end of the study period and examined at post mortem. Transmission of infection to an in-contact animal occurred in four of the 10 groups. One of the four in-contact animals, which became infected, had a retropharyngeal lymph node tubercle and M. bovis was isolated from lymph nodes without visible lesions from the other three. Two of the infected in-contact animals without visible lesions did not show any detectable cell-mediated immune response. There was no evidence that dietary restriction had any effect on transmission of disease.
Descriptors:  cattle, Mycobacterium bovis, tuberculosis, disease transmission, nutritional state, plane of nutrition, restricted feeding, loose housing.

De Lisle, G.W.; Yates, G.F.; Joyce, M.A.; Cavaignac, S.M.; Hynes, T.J.; Collins, D.M. Case report and DNA characterization of Mycobacterium avium isolates from multiple animals with lesions in a beef cattle herd.  Journal of Veterinary Diagnostic Investigation. 1998. 10 (3) 283-284.
NAL Call Number:  SF774 J68
Descriptors: 
Mycobacterium bovis, beef cattle, Mycobacterium avium complex, brushtail possums, herd monitoring, mesenteric lesions, post mortem examination, DNA restriction pattern, characterization, differential diagnosis, tuberculosis, New Zealand.

Delahay, R.J.; Cheeseman, C.L.; Mallinson, P.J.; Rogers, L.M.; Smith, G.C. Badgers and bovine tuberculosis: a review of studies in the ecology of a wildlife disease reservoir. Cattle Practice. 1998. 6 (2) 83-87.
NAL Call Number:  SF961 C37
Descriptors:
  Mycobacterium bovis, cattle, badgers, Meles meles, tuberculosis, wild animals as disease reservoirs, disease transmission, epidemiology.

Finlay, S. Krebs - one year on from recommendations towards a sustainable policy to control TB in cattle. State Veterinary Journal. 1998. 8 (4) 12-14.
NAL Call Number:  SF601 S8
Descriptors:  cattle, badgers, Meles meles, tuberculosis, Mycobacterium, disease prevention and control, wildlife disease reservoirs, vaccines, culling diseased animals.

Frost, B.  Research update on diagnostic tests for tuberculosis in llamas/alpacas. Proceedings One Hundred and Second Annual Meeting of the United States Animal Health Association, Minneapolis, Minnesota, USA, 3-9 October, 1998. United States Animal Health Association; Richmond; USA. 1998. p. 726-727.
NAL Call Number:  49.9 UN3R
Descriptors:
  Mycobacterium bovis, diagnostic tests, tuberculosis, llamas, alpacas.

Gonzalez-Llamazares, O.R.; Gutierrez-Martin, C.B.; Rodriguez-Ferri, E.F. Etiologia y diagnostico de la tuberculosis bovina.  [Aetiology and diagnosis of bovine tuberculosis.] Medicina Veterinaria. 1998. 15 (10) 514-537; 221. Note:  In Spanish with an English summary.
NAL Call Number:  SF604 A765
Descriptors:  cattle, etiology, diagnosis, bovine tuberculosis, Mycobacterium, Spain.

Griffin, F.; Bissett, B.; Rodgers, C.; Mackintosh, C. Uncontrollable spread of TB within a deer herd. Proceedings of a Deer Course for Veterinarians. 1998. No. 15, 227-231.
Descriptors:
  Mycobacterium, red deer, Cervus elaphus, tuberculosis, current disease incidence, UK.

Griffin, J.F.T.; Mackintosh, C.G.; Slobbe, L.; Thomson, A.J.; Buchan, G.S. Vaccine protocols to optimise the protective efficacy of BCG [in red deer]. Tubercle and Lung Disease. 1998. 79 (3) 135-143.
Descriptors:  red deer, Cervus elaphus, experimental infection, efficacy of BCG vaccination, intra-tonsillar injection, virulent Mycobacterium bovis, Mybacterium bovis BCG strain, pathogenesis, various vaccination doses, routes of vaccination, viability of vaccine, vaccine carriers, adjuvants, delayed high sensitivity, skin tests, post mortem examinations, New Zealand.

Gripper, J.  An open letter to Nick Brown, Minister of Agriculture... [Tuberculosis in cattle and badgers in the UK]. Veterinary Times. 1998. 28 (10) 4-6.
Descriptors:  cattle, badgers, Meles meles, Mycobacterium, tuberculosis, disease prevalence and control, disease transmission, wild animals, UK.

Gutierrez, M.; Tellechea, J.; Garcia-Marin, J.F.  Evaluation of cellular and serological diagnostic tests for the detection of Mycobacterium bovis-infected goats.  Veterinary Microbiology. 1998. 62 (4) 281-290.
NAL Call Number:  SF601 V44
Descriptors:
  Mycobacterium bovis, goats, tuberculosis, ELISA based diagnostic tests, disease, detection, tuberculin, IFN-gamma assay, blood, serum, interferon, assays, immunological techniques.

Hernandez, J.; Baca, D. Effect of tuberculosis on milk production in dairy cows.  Journal of the American Veterinary Medical Association.  Sept 15, 1998.  213 (6) 851-854. ISSN: 0003-1488
NAL Call Number:  41.8 Am3
Descriptors:  dairy cows, tuberculosis, Mycobacterium bovis, milk production, losses, dairy herds, tuberculin, tests.

Kovacic, H.; Cvetnic, Z.; Majnaric, D.; Krznaric, M.; Tomac, A.; Separovic, S.; Balenovic, T. Stanje tuberkuloze u goveda od 1992. do 1997 godine u Hrvatskoj. [The occurrence of tuberculosis in cattle in Croatia from 1992 to 1997.] Zbornik Radova. Hrvatska veterinarska komora; Zagreb, Croatia 1998. p. 117-122. Note:Veterinarski dani 1998. Rovinj, Croatia, 13-17 October 1998. In Croation with an English summary.
Descriptors:  tuberculosis, Mycobacterium, cattle, incidence of disease, disease diagnosis.

Krebs, J.R.; Anderson, R.M.; Clutton-Brock, T.; Donnely, C.A.; Frost, S.; Morrison, W.I.; Woodroffe, R.; Young, D. Badgers and bovine TB: conflicts between conservation and health. Science.  Feb 6, 1998. 279 (5352) 817-818. ISSN: 0036-8075
NAL Call Number:  470 Sci2
Descriptors:  cattle, Badgers, Meles meles, Mycobacterium, tuberculosis, disease transmission, male animals, disease control, Great Britain.

Krebs, J.R. Bovine tuberculosis in cattle and badgers. State Veterinary Journal. 1998. 8 (1) 1-3.
NAL Call Number:  SF601 S8
Descriptors:  cattle, Mycobacterium bovis, badgers, Meles meles, tuberculosis, UK.

Kumar, G.S.; Sharma, A.K.; Iyer, P.K.R.; Prasad, M.C.  Tuberculosis in crossbred dairy cattle.  Indian Journal of Veterinary Pathology. 1998. 22 (1) 11-15.
NAL Call Number:  SF769 A1I48
Descriptors:  cattle, Mycobacterium bovis, Mycobacterium tuberculosis, Mycobacterium chelonae, tuberculosis, diagnosis, lungs and associated lymph nodes, mortality, disease prevalence, isolation, Uttar Pradesh, India.

Kumar, G.S.; Parihar, N.S.  Haemato-biochemical picture in buffaloes induced with Mycobacterium bovis.  Indian Journal of Animal Sciences. 1998. 68 (9) 923-924.
NAL Call Number:  41.8 IN22
Descriptors:  buffalo, Mycobacterium bovis, hematology, blood chemistry profile, tuberculosis, India.

Kumar, G.S.; Parihar, N.S. Isolation of mycobacteria from suspected cases of pulmonary tuberculosis in buffaloes slaughtered for food. Indian Journal of Animal Sciences. 1998. 68 (6) 555-556.
NAL Call Number:  41.8 IN22
Descriptors:  food safety, buffalo meat, epidemiology, histopathology, disease incidence, isolation, lesions, lungs, lymph nodes, tuberculosis, zoonoses, buffalo, Mycobacterium bovis, Mycobacterium tuberculosis, Uttar Pradesh, India.

Kumar, G.S.; Parihar, N.S. Respiratory ailments in Indian buffaloes. Buffalo Journal. 1998. 14 (1) 109-114.
Descriptors:  lungs mediastinal lymph nodes, post slaughter tissue, pneumonia, lesions, disease surveys, Mycobacterium, neoplasms, tuberculosis, fascioliasis, disease prevalence, epidemiology, metacestodes, parasites, helminthes, buffaloes, Uttar Pradesh, India.

Liebana, E.; Aranaz, A.; Urquia, J.J.; Mateos, A.; Dominquez, L. Evaluation of the gamma-interferon assay for eradication of tuberculosis in a goat herd. Australian Veterinary Journal.  Jan 1998. 76 (1) 50-53. ISSN: 0005-0423
NAL Call Number:  41.8 Au72
Descriptors:  goats, kids, Mycobacterium bovis, tuberculosis, interferon, assays, diagnostic techniques, skin tests, tuberculin, disease control, flocks, diagnostic value.

Lightbody, K.A.; Skuce, R.A.; Neill, S.D.; Pollock, J.M. Mycobacterial antigen-specific antibody responses in bovine tuberculosis: an ELISA with potential to confirm disease status. Veterinary Record.  Mar 21, 1998. 142 (12) 295-300. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  Mycobacterium bovis, tuberculosis, ELISA, bacterial antigens, recombinant proteins, immune response, IgG, skin tests.

Lilenbaum, W.; Schettini, J.; Ribeiro, E.R.; de Souza, G.N.; Moreira, E.C.; Fonseca.  Tuberculose bovina: prevalencia e estudo epidemiologico em treze propriedades de diferentes sistemas de producao na regiao dos lagos do Estado do Rio de Janeiro. [Bovine tuberculosis: prevalence and epidemiology on 13 farms in the lakes region of Rio de Janeiro State, Brazil.]  Revista Brasileira de Medicina Veterinaria. 1998. 20 (3) 120-123. Note:  In Portuguese with an English summary.
NAL Call Number:  SF604 R38
Descriptors:  cattle, Mycobacterium bovis, 13 farms, intradermal skin test, disease prevalence of TB, differences related to farming system, Brazil.

Lis, H. Ocena wystepowania i zwalczania gruzlicy bydla w Polsce. [Epidemiology of bovine tuberculosis in Poland.]  Medycyna Weterynaryjna. 1998. 54 (9) 611-614. Note:  In Polish with an English summary.
NAL Call Number:  41.8 M463
Descriptors:  cattle, disease prevalence, disease surveys, diagnosis, bovine tuberculosis, Mycobacterium, bacterial diseases; cattle diseases, Poland

Lis, H. Ocena wynikow badania sanitarno-weterynaryjnego swin rzeznych w Polsce w 1994r. [Inspection of pigs slaughtered in Poland in 1994.Medycyna Weterynaryjna. 1998. 54 (6) 417-420. Note:  In Polish with an English summary.
NAL Call Number:  41.8 M463
Descriptors:  pigs, ante- and post-mortem examination, condemned carcasses, abscesses, echinococcosis, parasitoses, Mycobacterium tuberculosis, emaciation, Trichinella spiralis, trichinellosis, Poland.

Lugton, I.W.; Wilson, P.R.; Morris, R.S.; Nugent, G. Epidemiology and pathogenesis of Mycobacterium bovis infection of red deer (Cervus elaphus) in New Zealand.  New Zealand Veterinary Journal. 1998. 46 (4) 147-156.
NAL Call Number:  41.8 N483
Descriptors:  tuberculosis, epidemiology, pathogenesis, disease prevalence, diagnosis, detection, red deer, Cervus elaphus, wild animals, Mycobacterium bovis, New Zealand.

Lyashchenko, K.P.; Pollock, J.M.; Colangeli, R.; Gennaro, M.L. Diversity of antigen recognition by serum antibodies in experimental bovine tuberculosis. Infection and Immunity.  Nov 1998. 66 (11) 5344-5349. ISSN: 0019-9567
NAL Call Number:  QR1.I57
Abstract:  Tuberculosis in cattle remains a major zoonotic and economic problem in many countries. The standard diagnostic assay for bovine tuberculosis, the intradermal tuberculin test, has low accuracy. Therefore, alternative immunodiagnostic methods, such as serological assays, are needed for detection of infected animals. Development of an accurate serodiagnostic test requires a detailed understanding of the humoral immune responses during bovine tuberculosis and, in particular, identification of the key antigens of Mycobacterium bovis involved in antibody production. In this study, we characterized antibody responses in cattle experimentally infected with M. bovis. Sequential serum samples were collected every 3 to 4 weeks for up to 27 months postinfection. Circulating immunoglobulin G antibody levels were measured by an enzyme-linked immunosorbent assay using 12 highly purified recombinant proteins of M. bovis. Six proteins, ESAT-6, 14-kDa protein, MPT63, MPT70, MPT51, and MPT32, were identified as major seroreactive antigens in bovine tuberculosis. A remarkable animal-to-animal variation of antigen recognition by serum antibodies was observed. Kinetic analyses of the antibody production to individual antigens during infection revealed that the heterogeneous antigen recognition profile changed markedly in a given infected animal as disease progressed.
Descriptors:  antibody formation, experimental infections, Mycobacteriu bovis, antigen antibody reactions, IGG.

Mackereth, G.; Jackson, R. Spatial data and TB management. Publication - Veterinary Continuing Education, Massey University. 1998. No. 188, 19-25. Combined state and epidemiology and health management. Note:  75th Jubilee NZVA Conference 1998. 29 June to 2 July 1998. Rotorua Convention Centre, New Zealand.
NAL Call Number:  SF604 P82
Descriptors:
  Mycobacterium tuberculosis, cattle, tuberculosis, zoonoses, disease control, epidemiology, disease surveys, geographical information systems.

Mahato, G.; Rahman, H.; Sharma, K.K.; Pathak, S.C. Tuberculin testing in captive Indian elephants (Elephas maximus) of a national park. Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases. 1998. 19 (1) 63.
Descriptors:  elephants, Elephas maximus, zoo animals, tuberculin testing, tuberculosis, Mycobacterium, diagnostic techniques, diagnosis, India.

Mairtin, D.O.; Williams, D.H.; Dolan, L.; Eves, J.A.; Collins, J.D. The influence of selected herd factors and a badger-intervention tuberculosis-control programme on the risk of a herd-level trade restriction to a bovine population in Ireland. Preventive Veterinary Medicine. 1998. 35 (2) 79-90.
NAL Call Number:  SF601 P7
Descriptors:  cattle, tuberculin skin test, post slaughter testing, disease risks, Cox proportional hazard model, herd-level trade restriction, badger control program, wild animal disease reservoir, Mycobacterium bovis, Ireland.

McGinness, Stephen.  Bovine tuberculosis.  Research paper (Great Britain. Parliament. House of Commons. Library); 98/63. [London?], House of Commmons Library, [1998]
URL: http://www.parliament.uk/commons/lib/research/rp98/rp98-063.pdf
NAL Call Number:  SF967.T8 M34 1998
Descriptors:    tuberculosis in cattle, transmission, incidence, prevention and control,
Mycobacterium, Great Britain.

McGraw, L.  Diagnostic test for cattle tuberculosis. Agricultural Research.  Sept 1998. 46 (9) 17. ISSN: 0002-161X
URL:
http://www.ars.usda.gov/is/AR/
NAL Call Number:  1.98 Ag84
Descriptors:  Mycobacterium bovis, tuberculosis, diagnostic techniques, polymerase chain reaction.

Morishita, T.Y.; Fullerton, A.T.; Lowenstine, L.J.; Gardner, I.A.; Brooks, D.L. Morbidity and mortality in free-living raptorial birds of Northern California: a retrospective study, 1983-1994. Journal of Avian Medicine and Surgery. 1998. 12 (2) 78-81.
NAL Call Number:  SF994 J6
Descriptors:  owls, hawks, free-living raptors, mortality, morbidity, pathology, nutritional state, aspergillosis, Escherichia-infections, diagnosis, clinical aspects, nutritional disorders, causes of death, trauma and injuries, tuberculosis, Mycobacterium, avian cholera, fractures, underlying diseases, California.

Morris, C.A. Genetics of disease resistance in Bos taurus cattle. Animal Genetic Resources Information. 1998. No. 23, 1-11. Note:  In English with a Spanish summary.
Descriptors:  cattle, genetic variation, disease susceptibility, genetics, many diseases considered, parasites, mycotoxins, FMD, brucellosis, BSE, Mycobacterium, 25 year divergent selection experiment for pasture bloat, heritability estimates, New Zealand, Australia.

Morrison, W.I. Bovine tuberculosis: unresolved questions and future approaches to control. Cattle Practice. 1998. 6 (2) 75-77.
NAL Call Number:  SF961 C37
Descriptors:  cattle, badgers, Mycobacterium bovis, Meles meles, disease transmission and control, vaccination, England.

Nagy, G. A gamma-interferon-termeles kimutatasa gumokorral fertozott es paraallergias reakciot mutato szarvasmarha-allomanyokbol. Elozetes kozlemeny. [Detection of gamma-interferon production in cattle herds with tuberculosis or giving positive para-allergic reactions. Preliminary communication.] Magyar Allatorvosok Lapja. 1998. 120 (12) 711-713. Note:  In Hungarian with an English summary.
NAL Call Number:  41.8 V644
Descriptors:  cattle, Mycobacterium paratuberculosis, Mycobacterium bovis, Mycobacterium avium, tuberculosis, interferon, diagnosis, tuberculin, sandwich ELISA, gamma IF, fresh blood cultures with bovine of avian PPD, Hungary.

O'Keeffe, J.J.; Crowley, M.J. Tuberculosis in cattle: classifying breakdown episodes as a basis for decision making in eradication programmes. Proceedings of a Meeting, Society for Veterinary Epidemiology and Preventive Medicine. [Great Britain]. 1998. p. 28-37. ISSN: 0956-7496.  Note:  Meeting held on March 25-27, 1998, Ennis.
NAL Call Number:  SF780.9.S63
Descriptors:  cattle, Mycobacterium tuberculosis, prevention, control, eradication, government programs.

Ortatatli, M.; Ciftci, M.K.; Tuzcu, M. Sigirlarda tuberkuloz ve diger granulomatoz pnomoniler Uzerinde patolojik incelemeler. [Pathologic investigations on tuberculosis and other granulomatous pneumonia in cattle.] Veteriner Bilimleri Dergisi. 1998. 14 (2) 139-150. Note:  In Turkish with an English summary.
Descriptors:  cattle, lungs, mediastinal-bronchial lymph nodes, slaughter houses, granulomatous pneumonia, disease survey, tuberculosis, actinobacillosis, pneumomycosis, food safety, histopathology, Mycobacterium, Turkey.

Petukhov, V.L.; Kochnev, N.N.; Panov, B.L.; Korotkevich, O.S.; Kulikova, S.G.; Marenkov, V.G. Genetics of cattle resistance to tuberculosis. Proceedings of the 6th World Congress on Genetics Applied to Livestock Production, Armidale, NSW, Australia, 11-16 January, 1998. Volume 27:  Reproduction; fish breeding; genetics and the environment; genetics in agricultural systems; disease resistance; animal welfare; computing and information technology; tree breeding. Armidale; Australia:  Animal Genetics and Breeding Unit. 1998. p. 365-366.
NAL Call Number:  SF105 W67 1998
Descriptors:  cattle, cows, progeny, tuberculosis, heritability, bulls, morbidity, genetic selection, disease resistant cattle, Mycobacterium, Russia.

Prasad, H.; Roychoudhury, R.K.; Phukan, A.  Blood chemistry of tuberculous cows. Indian Veterinary Journal. 1998. 75 (2) 178-179.
NAL Call Number:  41.8 IN2
Descriptors:  serum samples, cattle, cows, calcium, magnesium, phosphorus, inorganic phosphorus, concentrations, possible diagnostic value, Mycobacterium.

Rathore, B.S. An epidemiological study on buffalo morbidity and mortality based on four year observations on 18 630 buffaloes maintained at 28 livestock farms in India. Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases. 1998. 19 (1) 43-49.
Descriptors:  buffalo morbidity and mortality, various factors, age, breed, sex, bacterial diseases, viral diseases, ketosis, nutritional deficiencies, hypoprotein anemia, FMD, rabies, tuberculosis, Mycobacterium, tetanus, parasites, flukes, worms, neoplasma, prevalence, diagnosis.

Roxo, E.; Vasconcellos, S.A.; Pinheiro, S.R.; Baruselli, P.S.; Macruz, R.; Leite, C.Q.L. Evaluation of tuberculin skin reaction in buffaloes (Bubalus bubalis). Arquivos do Instituto Biologico Sao Paulo. 1998. 65 (1) 81-92; 31. Note:  In English with a Portuguese summary.
NAL Call Number:  442.9 SA6
Descriptors:  buffalo, Bubalus bubalis, tuberculin skin test, evaluation, tuberculosis, Mycobacterium bovis, diagnostic techniques, Mycobacterium avium complex.

Ryan, T.J.; Livingstone, P.G.; Bailey, J.B.; Carter, C.E.; Crews, K.B.; Timbs, D.V. Tuberculosis control in livestock in New Zealand: the current situation and future directions. Proceedings of a Meeting, Society for Veterinary Epidemiology and Preventive Medicine [Great Britain]. 1998. p. 1-14. ISSN: 0956-7496.  Note:  Meeting held on March 25-27, 1998, Ennis.
NAL Call Number:  SF780.9.S63
Descriptors: 
Mycobacterium bovis, disease control, livestock tuberculosis, New Zealand.

Sala, V.; Antonini, M. Attualita e prospettive della tubercolosi suina. [Current aspects and the future of tuberculosis in pigs.]  Summa. 1998. 15 (3) 61-65. Note:  In Italian with an English summary.
Descriptors:  pigs, Mycobacterium avium, epidemiology, tuberculosis, current state of the disease, Italy.

Shehab, M.M. (ed.); El Tahlawy, M.R. (ed.); Mahmoud, M.R. Eighth Scientific Congress, Faculty of Veterinary Medicine, Assiut University, 15-17 November, 1998. Assiut; Egypt, Faculty of Veterinary Medicine, Assiut University; 1998. 927 pp. Note:  74 papers.
Descriptors:  livestock animals, cattle, camels, buffaloes, goats, sheep, rabbits, donkeys, dogs, pigs, mice, poultry, horses, rats, shrimp, many diseases, tuberculosis, brucellosis, aflatoxins, dermatitis, Mycobacterium.

Sheshagiri; Puttabyatappa, B.; Krishnappa, G.; Jhala, M.K. Assay of serum cytotoxicity levels in bovine tuberculin positive, doubtful and negative reactors.  Indian Veterinary Journal. 1998. 75 (8) 679-682.
NAL Call Number:  41.8 IN2
Descriptors:  cattle, Mycobacterium tuberculosis, diagnostic techniques, cell lines, intradermal test, L-929 cells, actinomyscin, diagnostic tests, tuberculosis, diagnosis, cytotoxicity, bacterial diseases, cattle diseases.

Signorini, G.C.; Nannipieri, S.; Biagi, G.; Rasori, P. Scambi intracomunitari di animali: problemi di polizia sanitaria. [Animal trade in the European Union: policing problems.] Atti della Societa Italiana di Buiatria. 1998. 30: 239-246. OTAUSO:  Congresso Nazionale, Piacenza, Italy, May 1998. Note:  In Italian with an English summary.
Descriptors:  European Union, international trade in animals, disease risks, FMD, Mycobacterium, tuberculosis, brucellosis, rabies, anthrax, leukosis, pleuropneumonia, legislation, disease control.

Sutmoller, P.; Taylor, P. An assessment of the risk of disease transmission by llama embryos. Proceedings One Hundred and Second Annual Meeting of the United States Animal Health Association, Minneapolis, Minnesota, USA, 3-9 October, 1998. United States Animal Health Association; Richmond; USA 1998. p. 251-275.
NAL Call Number:  49.9 UN3R
Descriptors:  llamas, artificial insemination, semen, embryo transfer, international trade, disease transmission, risk assessment, risk factors, foot and mouth disease, bluetougue virus, Brucella, Mycobacterium, Aphthovirus, methodology, contamination, epidemiology, Chile, US.

UK, State Veterinary Service. Focus on aspects of tuberculosis research. State Veterinary Journal. 1998. 8 (3) 3-4.
NAL Call Number:  SF601 S8
Descriptors:  cattle, Mycobacterium bovis, DNA fingerprinting, tuberculosis, research, vaccine development, diagnostic techniques, UK.

United States Animal Health Association. Proceedings:  One Hundred and Second Annual Meeting of the United States Animal Health Association, Minneapolis, Minnesota, USA, 3-9 October, 1998. Richmond:  The Association. 1998. 756 pp.
NAL Call Number:  49.9 UN3R
Descriptors:  livestock, pigs, cattle, bison, horses, llamas, poultry, aquaculture species, wildlife, animal welfare, biotechnology, disease outbreaks, feeds, food safety, international trade, parasitoses, drugs, environment, rabies, bluetongue virus; Retroviridae, Leptospira, Aujeszky virus, Salmonella, Mycobacterium bovis, Mycobacterium avium ssp. paratuberculosis, USA.

Vitale, F.; Capra, G.; Maxia, L.; Reale, S.; Vesco, G.; Caracappa, S. Detection of Mycobacterium tuberculosis complex in cattle by PCR using milk, lymph node aspirates, and nasal swabs.  Journal of Clinical Microbiology.  Apr 1998. 36 (4) 1050-1055. ISSN: 0095-1137
NAL Call Number:  QR46.J6
Descriptors:  cattle, diagnosis, polymerase chain reaction, diagnostic techniques, Mycobacterium tuberculosis.

Wahlstrom, H.; Englund, L.; Carpenter, T.; Emanuelson, U.; Engvall, A.; Vagsholm, I. A Reed-Frost model of the spread of tuberculosis within seven Swedish extensive farmed fallow deer herds. Preventive Veterinary Medicine. 1998. 35 (3) 181-193.
NAL Call Number:  SF601 P7
Descriptors:  farmed fallow deer, tuberculosis, disease transmission, zoonoses, epidemiology, herds, Reed-Frost mathematical models, estimate numbers of new infections, epidemics, Mycobacterium bovis, Sweden.

Wang, Z.G. Isolation and identification of atypical mycobacteria from cattle.  Journal of Jilin Agricultural University. 1998. 20 (2) 73-77. Note:  In Chinese with an English summary.
Descriptors:  atypical strain, cattle, lymph nodes, post slaughter tissue harvesting, Mycobacterium scrofulaceum, Mycobacterium fortuitum, Mycobacterium avium intracellulare complex, Mycobacterium paratuberculosis, Mycobacterium flavescens, an unknown rapid grower, China.

Wood, P.R.; Jones, S.L. Bovigam TM an internationally accredited diagnostic test for bovine tuberculosis  Proceedings One Hundred and Second Annual Meeting of the United States Animal Health Association, Minneapolis, Minnesota, USA, 3-9 October, 1998. United States Animal Health Association; Richmond; USA. 1998. p. 687-697.
NAL Call Number:  49.9 UN3R
Descriptors:  cattle, Mycobacterium bovis, Bovigam TM diagnostic test, methodology, diagnostic techniques, USA.

Zorawski, C.; Lipiec, M. Gruzlica bydleca i jej zwalczanie. [Bovine tuberculosis and its prevention.] Medycyna Weterynaryjna. 1998. 54 (8) 520-522. Note:  In Polish.
NAL Call Number:  41.8 M463
Descriptors:
  Mycobacterium, cattle, humans, epidemiology, public health risks, skin tests, tuberculin, wild animals, tuberculosis, disease prevention, Poland.

1997

Ali, O.A.; Abdel Salam, E.B. Incidence of animal diseases in Tripoli (Libya): a ten-year (1982-1991) pathological survey. Sudan Journal of Veterinary Science and Animal Husbandry. 1997. 36 (1-2) 141-148.
NAL Call Number:   41.9 SU22
Descriptors:  livestock animal diseases, dogs, pathology, abscesses, cirrhosis, coccidiosis, enteritis, hepatitis, leucosis, liver abscesses, liver flukes, lymphadenitis, Marek's disease, mastitis, pneumonia, poultry, Mycobacterium, tuberculosis, pasteurellosis, bovine mastitis, paratuberculosis, pulmonary adenomatosis, canine parvovirus, Libya.

Costello, E.; Egan, J.W.A.; Quigley, F.C.; O'Reilly, P.F. Performance of the single intradermal comparative tuberculin test in identifying cattle with tuberculous lesions in Irish herds.  Veterinary Record.  Aug 30, 1997. 141 (9) 222-224. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  cattle, Mycobacterium bovis, tuberculin skin tests, tuberculosis, herd health, chronic course, lesions, diagnostic value, Irish Republic.

Costello, E; O'Reilly, P.F.; Yearsley, D.K.; O'Grady, D.P.; O'Reilly, L.M.; Collins. J.D.; Monaghan, M.L.; Bassett, H.F. A study of an enzyme-liked immunosorbent assay for the diagnosis of tuberculosis in cattle.  Irish Veterinary Journal. 1997. 50 (1) 35-38.
NAL Call Number:  41.8 IR4
Descriptors:  disgnosis, cattle, Mycobacterium bovis, comparison study, three assay systems, ELISA on serum and tuberculin, anamnestic ELISA after intradermal incolution with tuberculin and ELISA using PPD (bovine and avian), not sensitive enough for herd testing.

Debbie, P.; Young, K.; Pooler, L.; Lamp, C.; Marietta, P.; Wagner, R. Allele identification using immobilized mismatch binding protein: detection and identification of antibiotic-resistant bacteria and determination of sheep susceptibility to scrapie.  Nucleic Acids Research.  Dec 1, 1997.  25 (23) 4825-4829. ISSN: 0305-1048
NAL Call Number:  QD341.A2N8
Descriptors:  sheep, scrapie, susceptibility, structural genes, alleles, animal proteins, identification, Mycobacterium tuberculosis, rifampicin, drug resistance, strains, DNA binding proteins, polymerase chain reaction, biotin, DNA probes, genotypes, animal prion proteins, biotin labeled probes, PRP gene, RPOB gene.

Ferreira-Neto, J.S.; Ferreira, F.; Fiaschitello, A.M.G.P.; Balian, S.C.; Faggin, G.; Farina, L. Andamento della tubercolosi bovina in Brasile. [Occurrence of bovine tuberculosis in Brazil.]  Rivista di Agricoltura Subtropicale e Tropicale. 1997. 91 (1) 31-41. Note:  In Italian with an English summary.
NAL Call Number:  S494.5 S86 J68
Descriptors:  bovine tuberculosis, prevalence, epidemiology, cattle, Mycobacterium bovis, Brazil.

Giron, D.O. Tuberculosis bovina (parte II).  [Bovine tuberculosis. Part II.]  Noticampo. 1997. No. 005, 5-9. Note:  In Spanish.
NAL Call Number:  S475 C7N67
Descriptors:  tuberculosis, symptoms, diagnosis, cattle, Mycobacterium bovis.

Gupta, V.K.; Ram, G.C.  Enzyme-linked immunosorbent assay for detection of Mycobacterium bovis antibodies in cattle.  Indian Journal of Animal Sciences. 1997. 67 (1) 3-6.
NAL Call Number:  41.8 IN22
Descriptors:  cows, antibody testing, PPD, glycolipid neoantigen (MB-O-BSA), ELISA, diagnosis.

Hernandez de Anda, J.; Renteria-Evangelista, T.; Lopez-Valencia, G.; Montano-Hodgers, M. An abattoir monitoring system for diagnosis of tuberculosis in cattle in Baja California, Mexico. [Erratum:  Dec 15, 1997. 211 (12), p. 1576.]. Journal of the American Veterinary Medical Association. Sept 15, 1997. 211 (6) 709-711. ISSN: 0003-1488
NAL Call Number:  41.8 Am3
Descriptors:  beef cattle, dairy cattle, tuberculosis monitoring, disease surveys, slaughter houses, disease prevalence, postmortem examinations, Mexico.

Higgins, A.J. Tuberculosis and badgers--facing up to facts. Veterinary Journal.  Mar 1997. 153 (2) 117-118. ISSN: 1090-0233
NAL Call Number:  SF601.V484
Descriptors:
  Mycobacterium tuberculosis, cattle, badgers, Meles meles, tuberculosis, reservoir hosts, disease control.

Hutchings, M.R.; Harris, S. Effects of farm management practices on cattle grazing behaviour and the potential for transmission of bovine tuberculosis from badgers to cattle. Veterinary Journal.   Mar 1997.  153 (2) 149-162. ISSN: 1090-0233
NAL Call Number:  SF601.V484
Abstract:  Despite the large body of circumstantial evidence to suggest a link, the means by which bovine tuberculosis is passed from badgers to cattle remains unclear; pasture contamination with the urine, faeces and/or sputum of infectious badgers is believed to be the main route of transmission. Therefore the behaviour of grazing cattle was studied to determine whether they avoided investigating and/or grazing pasture contaminated with badger excreta, and whether different farm management practices enhanced the potential for disease transmission. Active latrines were avoided by most cattle until the sward length in the rest of the field was reduced, after which there was an increasing likelihood that active badger latrines would be grazed. Most of the cattle grazed active badger latrines, but cattle of low rank within the herd grazed latrines more heavily. Farm management practices that reduced the availability of long swards shortened the period of investigative behaviour and greatly enhanced the risk that cattle would graze active badger latrines. Cattle were more likely to graze pasture away from latrines that was contaminated either with badger urine or single faeces. Because bacilli remain viable in the soil for up to 2 years, there is the potential for bacilli to accumulate at active badger latrines, and these could pose a significant risk to cattle, even when the latrine is no longer being used by badgers. Cattle readily grazed the lush sward at disused latrines, during which they could ingest contaminated soil; the amount of soil ingested increases as sward length decreases.
Descriptors:
  Mycobacterium, cattle tuberculosis, Meles meles, disease transmission, grazing, pasture contamination, excreta, plant height, rotational grazing, cutting of swards.

Kao, R.R.; Roberts, M.G.; Ryan, T.J. A model of bovine tuberculosis control in domesticated cattle herds. Proceedings of the Royal Society of London, Biological Sciences.  July 22, 1997. 264 (1384) 1069-1076. ISSN: 0962-8452
NAL Call Number:  501 L84B
Descriptors:  cattle, tuberculosis, Mycobacterium, disease control, mathematical models.

Khaled, K.; Dhaou, M.A. Pollutiones liees a l'activite des abattoirs. [Environmental pollution from abattoirs.]  Tunisie Medicale. 1997. 75 (5) 357-361. Note:  In French.
Descriptors:  animal wastes, slaughter plants, abattoirs, slaughterhouse waste, polluted liquid wastes, carcasses, blood, tuberculosis, Salmonella, Mycobacterium,coliform bacteria, composting waste disposal, public health, Tunisia.

Krebs, John R. Great Britain. Ministry of Agriculture, Fisheries and Food. Scottish Office. Agriculture, Environment and Fisheries Dept. Welsh Office. Agriculture Dept. The Government's Response to the Krebs Report on Bovine Tuberculosis in Cattle and Badgers. London, Ministry of Agriculture, Fisheries and Food, c1997. [8] p.
NAL Call Number:  SF967.T8G74 1997
Descriptors:  tuberculosis in cattle, badgers, Mycobacterium, Meles meles, disease reservoirs, prevention and control, Mycobacterium, Great Britain.

Krebs, J. R. (John R.) Independent Scientific Review Group (Great Britain ) Great Britian Ministry of Agriculture, Fisheries and Food. Bovine Tuberculosis in Cattle and Badgers:  Report to the Rt. Hon. Dr. Jack Cummingham, MP. London, Ministry of Agriculture, Fisheries and Food, 1997. 191 p.
NAL Call Number:  SF967.T8K74 1997
Descriptors:  tuberculosis, cattle, badgers, Meles meles, control, prevention, badgers, disease reservoirs, Mycobacterium,Great Britain.

Kudi, A.C.; Kalla, D.J.U.; Alkali, Y.; Ladan, S.M.; Kudi, M.C.; Mai, H.  Abattoir survey of small ruminant diseases in Bauchi, Nigeria.  Revue d'Elevage et de Medecine Veterinaire des Pays Tropicaux. 1997. 50 (4) 281-284. Note:  In English with French and Spanish summaries.
NAL Call Number:  41.8 R3262
Descriptors:  sheep, goats, post slaughter examinations, most common diseases seen, helminthosis, pneumonia, tuberculosis, seasonal effects, species effects, sex effects, disease prevelance, parasites, rainy season, tape worms, flukes, Mycobacterium, Nigeria.

Latini, O.; Canal, A.M.; Ferrara, M.E.; Sequeira, M.D.; Sequeira, G.; Bagnaroli, R.; Torres, P. Confiabilidad en la determinacion de prevalencia de infeccion por Mycobacterium bovis en ganado bovino por decomisos en frigorificos. [The reliability of using carcass condemnation in abattoirs to determine the prevalence of Mycobacterium bovis in cattle.] Archivos de Medicina Veterinaria. 1997. 29 (2) 197-204. Note:  In Spanish with an English summary.
NAL Call Number:  SF604 A75
Descriptors:    post-slaughter carcass condemnation, meat inspection, tuberculosis, diagnosis, disease control, Mycobacterium bovis, cattle,
Argentina.

Leifsson, P.S.; Olsen, S.N.; Larsen, S. Ocular tuberculosis in a horse. Veterinary Record.  Dec 20/27, 1997. 141 (25) 651-654. ISSN: 0042-4900
NAL Call Number:  41.8 V641
Descriptors:  horses, tuberculosis, Mycobacterium avium, eyes, pathology, blindness, atypical disease course, case reports

Lensch, J.H.; Geilhausen, H.E.; Yang, RongZhen (ed.); Han, XingTai (ed.); Luo, XiaoLin Infectious and parasitic diseases in the yak. Yak production in Central Asian Highlands. Proceedings of the second international Congress on Yak, Xining, China, 1-6 September, 1997. Qinghai People's Publishing House; Xining; China. 1997. p. 223-228.
Descriptors:  overview, diseases of the yak, zoonotic diseases, ectoparasites, infectious diseases, FMD, rinderpest, rabies, stomatitis, cowpox, hemorrhagic septicaemia, Mycobacterium tuberculosis, brucellosis, lymphadenitis, mastitis, endometritis, coliform bacteria, conjunctivitis, fascioliasis, helminthes, helminthoses, parasitoses, ectoparasitoses, parasites, Aphthovirus, Pasteurella multocida, Brucella, Chlamydia, Hypoderma bovis, Metastigmata, Ixodidae ticks, Fasciola hepatica, Asia.

Lyashchenko, K.P.; Bilko, I.P.; Kolesnikova, I.N.; Lyashko, E.D.; Matyash, M.A.; Mikhalsky, L.A.; Smirnov, V.V.; Komissarenko, S.V. Specific identification of Mycobacterium bovis by monoclonal antibody-based enzyme immunoassay. Mikrobiologichnii Zhurnal. 1997. 59 (3) 46-53. Note:  In English with Ukrainian and Russian summaries.
Descriptors:  ELISA, mouse monoclonal antibodies, differential diagnosis, western blot analysis, Mycobacterium bovis, Mycobacterium avium complex, Mycobacterium smegmatis, Mycobacterium tuberculosis, polyclonal and cross reactive monoclonal antibodies, species identification.

Monaghan, M.; Quinn, P.J.; Kelly, A.P.; McGill, K.; McMurray, C.; O'Crowley, K.; Bassett, H.F.; Costello, E.; Quigley, F.; Rothel, J.S.; Wood, P.R.; Collins, J.D. A pilot trial to evaluate the gamma-interferon assay for the detection of Mycobacterium bovis infected cattle under Irish conditions. Irish Veterinary Journal. 1997. 50 (4) 229-232.
NAL Call Number:  41.8 IR4
Descriptors:  IFN-gamma assay, Mycobacterium bovis, cattle, intradermal tuberculin test, diagnostic test, Irish Republic.

Ng, K.H.; Aldwell, F.E.; Wedlock, D.N.; Watson, J.D.; Buddle, B.M. Antigen-induced interferon-gamma interleukin-2 responses of cattle inoculated with Mycobacterium bovis. Veterinary Immunology and Immunopathology.  June 1997.  57 (1/2) 59-68. ISSN: 0165-2427
NAL Call Number:  SF757.2.V38
Abstract:  Bovine purified protein derivative (PPD)-induced interferon-gamma (IFN-gamma) and interleukin-2 (IL-2) mRNA expression was measured in peripheral blood lymphocyte cultures of cattle inoculated with Mycobacterium bovis and compared to cytokine protein levels as measured by IFN-gamma enzyme-linked immunosorbent assay and IL-2 bioassay. For individual animals, positive correlations were observed between mRNA and protein levels of bovine PPD-induced IFN-gamma and IL-2, although the correlations were stronger for IFN-gamma. Expression of these two cytokines also correlated with responses from a comparative intradermal test and a M. bovis antibody test. At 7 and 20 weeks after inoculation, bovine PPD-induced IFN-gamma and IL-2 mRNA expression was detected in all animals with tuberculous lesions and in a proportion of the M. bovis-inoculated animals with no lesions. Correlation of antigen-induced IFN-gamma and IL-2 with other immune parameters suggests that these two cytokines play an important role in the immune response to bovine tuberculosis.
Descriptors:  lymphocyte cultures, cattle, experimental inoculation, Mycobacterium bovis, PPD IFN, IL2, mRNA expression. Immune response, cytokines, bovine tuberculosis.

Resende, J.; Palis-Aguiar, P.H.; de Noronha-Gomes, N.B. Tuberculose genital em bufalo - relato de um caso. [Genital tuberculosis in buffalo bulls - case report.] Arquivos da Escola de Medicina Veterinaria da Universidade Federal da Bahia. 1997. 19 (1) 74-79. Note:  In Portuguese with an English summary.
Descriptors:  case reports, buffalos, bulls, male genitalia, tuberculosis, pathology, histopathology, clinical aspects, symptoms, diagnosis, treatment, castration, Mycobacterium, Brazil.

Schijns, V.E.C.J. (ed.); Horzinek, M.C. Cytokines in veterinary medicine. Wallingford, UK, CAB International. 1997 xxiv+324 pp.
NAL Call Number:  SF757.25 C997 1997
Descriptors:  diagnosis of tuberculosis, Mycobacterium, sheep, pigs, horses, avian, cats, cytokines in disease, responses and regulation, interferon-gamma assay.

Schmitt, S.M.; Fitzgerald, S.D.; Cooley, T.M.; Bruning-Fann, C.S.; Sullivan, L.; Berry, D.; Carlson, T.; Minnis, R.B.; Payeur, J.B.; Sikarskie, J. Bovine tuberculosis in free-ranging white-tailed deer from Michigan. Journal Wildlife Disease.  Oct 1997.  33 (4) 749-758. ISSN: 0090-3558
NAL Call Number:  41.9 W64B
Descriptors:  white-tailed deer, Odocoileus virginianus, Mycobacterium bovis,  wild animals, bovine tuberculosis.

Sun, L.; Kang, D.; Ge, X.; Sun, J.H.; Li, R.Z. Application of PPA-ELISA for the detection of avian tuberculosis antibody in chicken serum. Chinese Journal of Animal Quarantine. 1997. 14 (3) 11-13. Note:  In Chinese.
Descriptors:
  Mycobacterium avium, antibodies, rabbit anti-chicken IgG immune serum, diagnostic test, PPA-ELISA, chickens, experimental infections, test sensitivity, test specificity and cost, SPF flocks.

Torres, P.; Antognoli, M.C.; Moreira, A.R.; de Kantor, I.N. de. La vacuna antiaftosa con adyuvante oleoso y su posible influencia en el diagnostico de la tuberculosis en bovinos. [Foot and mouth disease oil-adjuvant vaccine and its possible role in the diagnosis of tuberculosis in cattle.] Boletin del Centro Panamericano de Fiebre Aftosa. 1997. No. 62-63, 39-42. Note:  In Spanish with a English and Portuguese summary.
NAL Call Number:   SF793 P3
Descriptors:  cattle, Mycobacterium bovis, tuberculosis, diagnosis, foot and mouth disease, humoral immunity, adjuvants, vaccines, effects of vaccination, ELISA.

United States Animal Health Association.  Proceedings One Hundred and First Annual Meeting of the United States Animal Health Association, Louisville, Kentucky, USA, 18-24 October, 1997. Richmond, Va,  The Association. 1997. 619 pp.
NAL Call Number:  49.9 UN3R
Descriptors:  issues of disease control, animal diseases and animal production, disease surveillance and animal health systems, bluetongue and bovine retrovirus; brucellosis, captive wildlife and alternative livestock, environmental residues, biosafety, foreign animal diseases, infectious diseases, sheep, goats, pigs, wildlife, poultry, cattle, bison, llama, horses, Mycobacterium, Johne's disease, leptospirosis, parasitic diseases, pseudorabies, rabies, Salmonella, tuberculosis.

United States. Food Safety and Inspection Service.  Tuberculosis: what you need to know. Washington, D.C., FSIS, [1997]
URL:
http://www.fsis.usda.gov/OPHS/tbbroch.htm
NAL Call Number:  aRA644.T7T83 1997
Descriptors:  tuberculosis in animals, food safety, United States.

HISTORICAL DOCUMENT

Smith, T. Some practical suggestions for the suppression and prevention of bovine tuberculosis. Yearbook. United States Dept. Agriculture, Washington, G.P.O., 1895-1920. 1894 (pub. 1895). p. 317-330. Bulletin. United States Dept. of Agriculture,  Division of Publications.
NAL Call Number:  1Ag84Y
Descriptors:  dairy cows, tuberculosisMycobacterium bovis, disease control, disease prevention,  zoonoses, USA.  

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