Animal Welfare Information Center

Johne's Disease--Mycobacterium avium subsp. paratuberculosis: A Debilitating Enteric Disease of Ruminants


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2003


Abbott, K.A.; Whittington, R.J.  Monte Carlo simulation of flock-level sensitivity of abattoir surveillance for ovine paratuberculosis.  Preventive Veterinary Medicine.  2003; 61(4): 309-332.  ISSN:  0167-5877.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5145&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=c5bc3d9e1bb66468352ae1f5475d522
NAL Call No.:  SF601.P7
Descriptors:  sheep, disease survey, Mycobacterium avium subsp. paratuberculosis, post slaughter data, disease prevalence, epidemiology, Monte Carlo simulation model for flock level sensitivity to Johne’s disease, comments on the usefulness of the approach.

Adaska, John M.; Anderson, Randall J.  Seroprevalence of Johne's-disease infection in dairy cattle in California, USA.  Preventive Veterinary Medicine.  2003; 60(3): 255-261.  ISSN:  0167-5877.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5145&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=c5bc3d9e1bb66468352ae1f5475d522f
NAL Call No.:  SF601.P7
Descriptors:  dairy cattle, 65 dairy herds, Mycobacterium avium subsp. paratuberculosis, disease distribution, disease prevalence, seroprevalance, 1950 serum samples, antibody testing, ELISA kit, epidemiology, paratuberculosis, regional disease data, California, United States.

Aho, Abraham D.; McNulty, Amanda M.; Coussens, Paul M.  Enhanced expression of interleukin-1alpha and tumor necrosis factor receptor-associated protein 1 in ileal tissues of cattle infected with Mycobacterium avium subsp. paratuberculosis.  Infection and Immunity.  2003; 71(11): 6479-6486.  ISSN:  0019-9567.
URL:  http://www.jarvm.com/
NAL Call No.:  QR1.I57
Descriptors:  Holstein cattle, Mycobacterium avium subsp. paratuberculosis, comparison study, disease positive and negative, gene expression profiles of ileal tissues, gene expression profiles, bovine total leukocyte (BOTL-3) cDNA microarray, infected animals, tumor necrosis factor receptor-associated protein 1 (TRAF1), interleukin-1alpha (IL-1alpha), MCP-2, N-cadherin, and beta1 integrin (CD29), upregulation of IL-1alpha (21.5-fold) and TRAF1 (27.5-fold) gene expression in tissues of Johne's disease positive.

Ahrens, P.; Bolske, G.; Djonne, B.; Klausen, J.; Christensen, B. [Editors]  Paratuberculosis, Proceedings of the 15th Symposium of the Nordic Committee for Veterinary Scientific Cooperation (NKVet), Copenhagen, Denmark, 18-19 May 2001.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 207-295.  ISSN:  0044-605X.
NAL Call No.:  41.8 AC87
Descriptors:  goats, Johne’s disease, present knowledge, eradication, diagnosis, control programs and strategies, Mycobacterium avium subsp. paratuberculosis, possible cause of Crohn’s disease in humans, herd level antibodies, milk contamination, Denmark, Finland, Iceland, Norway, Sweden.

Anonymous.  Animal health following drought. Agnote DAI-224.  Agnote NSW Agriculture. 2003; (DAI-224 (2nd Edition)): 8 p.  ISSN:  1034-6848.
Descriptors:  cattle, bulls, Johne’s disease, animal health, animal welfare, stocking density, vaccination, drought grass tetany, brucellosis, helminthes, leptospirosis, New South Wales, Australia.

Arsenault, J.; Girard, C.  Particularites ovines de la paratuberculose.  [Particularities of ovine paratuberculosis.]  Medecin Veterinaire du Quebec.  2003; 33(1-2): 28-31.  ISSN:  0225-9591.  Note:  In French.  
Descriptors:  sheep, Johne’s disease, clinical aspects, diagnosis, disease transmission, disease prevention and control, risk factors, paratuberculosis.

Arsenault, Julie; Girard, Christiane; Dubreuil, Pascal; Daignault, Danielle; Galarneau, Jean Rene; Boisclair, Julie; Simard, Carole; Belanger, Denise.  Prevalence of and carcass condemnation from maedi-visna, paratuberculosis and caseous lymphadenitis in culled sheep from Quebec, Canada.  Preventive Veterinary Medicine.  2003; 59(1-2): 67-81.  ISSN:  0167-5877.  
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5145&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=c5bc3d9e1bb66468352ae1f5475d522f
NAL Call No.:  SF601.P7
Descriptors:  culled sheep, ewes, rams, Corynebacterium pseudotuberculosis, Mycobacterium avium subsp. paratuberculosis, lung and mammary gland lesions, caseous lymphadenitis, ELISA testing, histologic lesions in terminal ileum, ileocecal lymph node/ ileocecal valve, sex and age differences, carcass condemnation, disease distribution, disease prevalence, epidemiology, lymphadenitis, paratuberculosis, seroprevalence, sex differences, visna maedi virus, Quebec, Canada.

Australia NSW OJD Advisory Committee.  Future Management of OJD is in Your Hands.  2003; 5 p.
Descriptors:  sheep, Johne’s disease, disease control, disease prevalence, disease prevention, Australia.

Balseiro, A.; Prieto, J.M.; Espi, A.; Perez, V.; Garcia-Marin, J.F.  Presence of focal and multifocal paratuberculosis lesions in mesenteric lymph nodes and the ileocaecal valve of cattle positive to the tuberculin skin test.  Veterinary Journal.  2003; 166(2): 210-212.  ISSN:  1090-0233.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=7163&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=f68d9c40dd58509407a11a133122c879
NAL Call No.:  SF601.V484
Descriptors:  cattle, animal with positive (91 animals) and negative (43 animals) tuberculin skin tests, immunohistochemistry testing for Mycobacterium avium subsp. paratuberculosis, small intestine, cecum, mesenteric lymph nodes, ileum, ileocecal valve, clinical aspects, granulomas, mesentery, pathology.

Bannantine, J.P.; Hansen, J.K.; Stabel, J.R.; Kapur, V.  Evaluation of novel Mycobacterium avium subsp. paratuberculosis antigens as potential diagnostic reagents.  Abstracts of the General Meeting of the American Society for Microbiology.  2003; 103: U-051.  ISSN:  1060-2011.  Note:  103rd American Society for Microbiology General Meeting, Washington, DC, USA; May 18-22, 2003.  
Descriptors:  Mycobacterium avium subsp. paratuberculosis, Mycobacterium avium subsp. avium, differentiation between the 2 species, 21 predicted coding sequences unique to MAP, amplified and cloned into an E. coli expression vector, immunoblotting studies, sera from rabbits and mice, 5 gene products detected in all sera, same proteins in infected cattle, method to identify novel antigens.

Bannantine, John P.; Zhang, Qing; Li, Ling Ling; Kapur, Vivek.  Genomic homogeneity between Mycobacterium avium subsp. avium and Mycobacterium avium subsp. paratuberculosis belies their divergent growth rates.  BMC Microbiology.  2003; 3(10): (Cited June 13, 2003).  ISSN:  1471-2180.  
URL:  http://www.biomedcentral.com/1471-2180
Descriptors:  Mycobacterium avium, Mycobacterium avium subsp. avium, Mycobacterium avium subsp. paratuberculosis, nucleotide sequences, genome similarities, genomic comparison study, oligonucleotide primers, conserved gene order in the oriC locus of Mycobacterium avium subsp. paratuberculosis, genetic variation between species, growth rate differences, open reading frames.

Bannantine, John P.; Huntley, Jason F.J.; Miltner, Elizabeth; Stabel, Judith R.; Bermudez, Luiz E.  The Mycobacterium avium subsp. paratuberculosis 35 kDa protein plays a role in invasion of bovine epithelial cells.  Microbiology.  2003; 149(8): 2061-2069.  ISSN:  1350-0872.
URL:  http://mic.sgmjournals.org/contents-by-date.0.shtml
NAL Call No.:  QR1.J64
Descriptors:  cattle, Mycobacterium avium subsp. paratuberculosis, E. coli , Johne’s disease, antibodies, DNA cloning, gene expression, 35kDa major membrane proteins (MMP), bacterial invasion of bovine epithelial cells, intestinal environment of low oxygen and high osmolarity, surface proteins, virulence factors.

Barrington, G.M.; Gay, J.M.; Eriks, I.S.; Davis, W.C.; Evermann, J.F.; Emerson, C.; O' Rourke, J.L.; Hamilton, M.J.; Bradway, D.S.  Temporal patterns of diagnostic results in serial samples from cattle with advanced paratuberculosis infections.  Journal of Veterinary Diagnostic Investigation.  2003; 15(2): 195-200.  ISSN:  1040-6387.
NAL Call No.:  SF774.J68
Descriptors:  cows, Mycobacterium avium subsp. paratuberculosis, diagnosis, diagnostic techniques and strategies, ELISA, paratuberculosis, PCR of blood, milk, liver, feces, temporal variation, fecal cultures, diagnostic sensitivity figures.

Benedictus, G.; Kalis, C.J.H.  Paratuberculosis: eradication, control and diagnostic methods.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 231-241.  ISSN:  0044-605X.
NAL Call No.:  41.8 AC87
Descriptors:  sheep, goats, cattle, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, control programs, culling of sick animals, diagnostic techniques, disease control, vaccination, immunity, immunizations, reviews, ODGE.

Boegli-Stuber, K.; Glanemann, B.; Seitert, G.; Kohler, C.; Wittwer, M.; Wittenbrink, M.M.; Bissig-Choisat, B.  Development and validation of a real-time PCR assay for the detection of Mycobacterium avium subspecies paratuberculosis (MAP) in fecal samples and its correlation to culture.  FEMS Congress of European Microbiologists Abstract Book.  2003; (1): 54.  Note:  1st Federation of European Microbiological Societies (FEMS) Congress of European Microbiologists, Ljubljana, Slovenia; June 29-July 03, 2003.
Descriptors:  Mycobacterium avium subsp. paratuberculosis, fecal sampling, detection methods, real-time PCR.

Bolske, G.; Englund, S.  Ongoing research on paratuberculosis in Sweden.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 275-278.  ISSN:  0044-605X.
NAL Call No.:  41.8 AC87
Descriptors:  cattle, Mycobacterium avium subsp. paratuberculosis, research programs on Johne’s disease, control programs, diagnosis, diagnostic techniques, ELISA, PCR, Sweden.

Buddle, B.M.; McCarthy, A.R.; Ryan, T.J.; Pollock, J.M.; Vordermeier, H.M.; Hewinson, R.G.; Andersen, P.; De Lisle, G.W.  Use of mycobacterial peptides and recombinant proteins for the diagnosis of bovine tuberculosis in skin test-positive cattle.  Veterinary Record.  2003; 153(20): 615-620.  ISSN: 0042-4900.
URL:  http://veterinaryrecord.bvapublications.com/
NAL Call No.:  41.8 V641
Descriptors:  bovine tuberculosis, cattle, synthetic peptides, antigen detection, skin lesions, skin tests, paratuberculosis, diagnostic techniques, cross reaction, tuberculin, recombinant proteins, disease diagnosis, Mycobacterium bovis, interferons, skin folds, vaccination, Mycobacterium avium subsp. paratuberculosis, animal pathogenic bacteria.

Buergelt, C.D.; Williams, E.  In utero infection of pregnant cattle by Mycobacterium avium subspecies paratuberculosis detected by nested polymerase chain reaction.  Journal of Applied Research in Veterinary Medicine.  2003; 1(4): 279-284.  ISSN:  1471-2180.
URL:  http://www.jarvm.com/
NAL Call No.:  SF601.J63
Descriptors:  nested PCR using 2 sets of primers, detection of Mycobacterium avium subsp. paratuberculosis in fetal fluid and fetal tissues, 3 pregnant cows with clinical Johne’s disease, necropsy, various tissues tested, Mycobacterium avium subsp. paratuberculosis found in various tissues, PCR assay useful for in utero infection.

Bull, Richard.  Assessment of the NSW Ovine Johne's Disease Program: [Summary]. NSW Ministry of Agriculture, New South Wales.  [2003]; 51 p.  ISBN: 0734715358.  Note:  "September 2003."  “This report is presented by independent consultant Richard Bull to the NSW Minister for Agriculture, the Hon. Ian Macdonald."
NAL Call No.:  SF969.P34 B86 2003
Descriptors:  sheep, paratuberculosis, Mycobacterium avium subsp. paratuberculosis, assessment of the current Ovine Johne's Disease (OJD) program, recommendation for the future, New South Wales, Australia.

Bull, T.J.; Sidi-Boumedine, K.; McMinn, E.J.; Stevenson, K.; Pickup, R.; Hermon-Taylor, J.  Mycobacterial interspersed repetitive units (MIRU) differentiate Mycobacterium avium subspecies paratuberculosis from other species of the Mycobacterium avium complex. Molecular and Cellular Probes.  2003; 17(4): 157-164.  ISSN:  0890-8508.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=6959&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=a1d954773ca83f03ff7b5c0d870580ef
NAL Call No.:  RB43.7 M63
Descriptors:  Mycobacterium avium subsp. paratuberculosis, Mycobacterium avium subsp. avium, Mycobacerium avium complex, mycobacterial interspersed repetitive units, 18 conserved loci, 6 loci differ, locus specific PCR, Mycobacterium avium subsp. paratuberculosis segregated into 2 major groups, ovine pigmented Mycobacterium avium subsp. paratuberculosis and vaccine strains, Mycobacterium avium subsp. avium differentiated into 5 profiles, Mycobacterium intracellulare, mycobacterial interspersed repetitive units locus 1 and mycobacterial interspersed repetitive units locus 4 distinguished between Mycobacterium avium subsp. paratuberculosis and Mycobacerium avium complex.

Buza, Joram J.; Mori, Yasuyuki; Bari, Abusaleh M.; Hikono, Hirokazu; Aodon Geril; Hirayama, Sachiyo; Shu, Yujing; Momotani, Eiichi.  Mycobacterium avium subsp. paratuberculosis infection causes suppression of RANTES, monocyte chemoattractant protein 1, and tumor necrosis factor alpha expression in peripheral blood of experimentally infected cattle. Infection and Immunity.  2003; 71(12): 7223-7227.  ISSN:  0019-9567.
URL:  http://www.jarvm.com/
NAL Call No.:  QR1.I57
Descriptors:  Holstein cattle, experimental infection, Mycobacterium avium subsp. paratuberculosis, immune response, chemokines, interleukin-1, tumour necrosis factor alpha, interleukin 8, monocyte chemotactic protein 1, RANTES, weakening of protective immunity.

Caspersen, O.  Spildt ko: afmagrede malkekoer med Darlig velfaerd er et stigende problem.  Wasted cows.  [Emaciated dairy cattle with poor welfare status are a growing problem.]  Dansk Veterinaertidsskrift.  2003; 86(17): 12-14.  ISSN:  0106-6854.  Note:  In Danish.
Descriptors:  dairy cattle, generalized muscular atrophy, failing pre-slaughter inspection, post mortem inspections show chronic intestinal inflammation, probably Mycobacterium avium subsp. paratuberculosis, increasing trend, economic costs, animal welfare concerns, Denmark.

Checkley, S.L.; Waldner, C.L.; Appleyard, G.D.; Campbell, J.R.; Forsythe, L.A.; Janzen, E.D.  The comparison of 5 diagnostic tests for diagnosis of Johne's disease in Western Canada.  Journal of Applied Research in Veterinary Medicine.  2003; 1(3): 196-205.  ISSN:  1542-2666.  
URL:  http://www.jarvm.com/
NAL Call No.:  SF601.J63
Descriptors:  5 diagnostic tests for Mycobacterium avium subsp. paratuberculosis, Johne’s disease compared, 1) ELISA, 2) fecal culture slants of HEYM, 3) AGID, 4-5) 2 PCR, 5 populations of cattle, testing results varied with populations, Canada.

Christopher-Hennings, J.; Dammen, M.A.; Weeks, S.R.; Epperson, W.B.; Singh, S.N.; Steinlicht, G.L.; Fang, Y.; Skaare, J.L.; Larsen, J.L.; Payeur, J.B.; Nelson, E.A.  Comparison of two DNA extractions and nested PCR, real-time PCR, a new commercial PCR assay, and bacterial culture for detection of Mycobacterium avium subsp. paratuberculosis in bovine feces.  Journal of Veterinary Diagnostic Investigation.  2003; 15(2): 87-93.  ISSN:  1040-6387.
NAL Call No.:  SF774.J68
Descriptors:  cattle, bacterial diseases, Johne’s disease, detection of Mycobacterium avium subsp. paratuberculosis, fecal testing, 5 combinations of 2 DNA extractions and 3 polymerase chain reaction (PCR) techniques, compared, diagnostic techniques, southern blotting, all showed similar sensitivities.

Collins, M.T.  Paratuberculosis: review of present knowledge.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 217-221.  ISSN:  0044-605X.  Note:  Review article.
NAL Call No.:  41.8 AC87
Descriptors:  cattle, humans, Mycobacterium avium subsp. paratuberculosis, Crohn’s disease, Johne’s disease, pathogenesis, clinical aspects, disease prevalence, disease prevention and control, economic impacts of disease, potential zoonotic disease, food safety, public health concerns.

Collins, M.T.  Update on paratuberculosis. 1. Epidemiology of Johne's disease and the biology of Mycobacterium paratuberculosis.  Irish Veterinary Journal.  2003; 56(11): 565-574.  ISSN:  0368-0762.
Descriptors:  Mycobacterium avium subsp. paratuberculosis, Johne’s disease, epidemiology, host range of bacterial pathogen, disease distribution, disease prevalence, disease transmission, pathogenicity, virulence, survival mechanisms, cold tolerance, heat tolerance, pasteurization.

Collins, M.T.  Update on paratuberculosis. 2. Pathology and diagnosis.  Irish Veterinary Journal.  2003; 56(12): 619-620, 622-623.  ISSN:  0368-0762.
Descriptors:  goats, cattle, sheep, Johne’s disease, Mycobacterium avium subsp. paratuberculosis clinical aspects, lesions, histopathology, diagnosis, diagnostic techniques.

Corner, L.A.L.; Pfeiffer, D.U.; Abbott, K.A.  Unanswered questions about the transmission of Mycobacterium avium subspecies paratuberculosis.  Veterinary Journal.  2003; 165(3): 182-183.  ISSN:  1090-0233.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=7163&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=f68d9c40dd58509407a11a133122c879
NAL Call No.:  SF601.V484
Descriptors: cattle, Mycobacterium avium subsp. paratuberculosis, disease transmission, disease vectors.

Coussens, Paul M.; Colvin, Christopher J.; Rosa, Guilherme J.M.; Laspiur, Juliana Perez; Elftman, Michael D.  Evidence for a novel gene expression program in peripheral blood mononuclear cells from Mycobacterium avium subsp. paratuberculosis-infected cattle.  Infection and Immunity.  2003; 71(11): 6487-6498.  ISSN:  0019-9567.
URL:  http://www.jarvm.com/
NAL Call No.:  QR1.I57
Descriptors:  Holstein-Fresian cattle, infected and uninfected animals, Johne’s disease, Mycobacterium avium subsp. paratuberculosis, gene expression profiles, peripheral blood mononuclear cells (PBMCs) cell mediated immunity, in vivo and in vitro comparison, gene expression, complementary DNA, immune response, interferon, lymphocytes, molecular genetics.

Cywinska, A.; Bas, M.  Czy paratuberkuloza jest zoonoza?  [Is paratuberculosis a zoonosis?].  Zycie Weterynaryjne.  2003; 78(3): 155-160.  ISSN:  0137-6810.  Note:  In Polish with an English summary.
NAL Call No.:  SF604.Z9
Descriptors:  ruminants, humans, Mycobacterium avium subsp. paratuberculosis, Johne’s disease in animals, Crohn’s disease in humans, disease transmission possibilities, raw milk, food contamination, food safety, zoonoses.

Dagleish, M.; Goddard, P.  Dealing with disease.  Deer Farming.  2003; (74): 23-25.
Descriptors:  deer, Johne’s disease, Mycobacterium avium subsp. paratuberculosis, diagnosis, pathology, epidemiology, pathogenesis, disease control, vaccination, United Kingdom.

Daniels, Mike J.; Hutchings, Michael R.; Beard, Philippa M.; Henderson, Dennis; Greig, Alastair; Stevenson, Karen; Sharp, J. Michael.  Do non-ruminant wildlife pose a risk of paratuberculosis to domestic livestock and vice versa in Scotland?  Journal of Wildlife Diseases.  2003; 39(1): 10-15.  ISSN:  0090-3558.
URL: http://www.jwildlifedis.org/
NAL Call No.:  41.9 W64B
Descriptors:  non-ruminant wildlife, Johne’s disease, Mycobacterium avium subsp. paratuberculosis, disease surveys, disease transmission, disease vectors, epidemiological surveys, epidemiology paratuberculosis, risk assessment, pasture contamination, rabbits, canid, mustelid, corvid, murids, review, Scotland.

Daniels, M.J.; Henderson, D.; Greig, A.; Stevenson, K.; Sharp, J.M.; Hutchings, M.R.  The potential role of wild rabbits Oryctolagus cuniculus in the epidemiology of paratuberculosis in domestic ruminants.  Epidemiology and Infection.  2003; 130(3): 553-559.  ISSN:  0950-2688.
URL:  http://journals.cambridge.org/action/displayJournal?jid=HYG&bVolume=y
NAL Call No.: RA651.A1E74
Descriptors:  cattle, sheep, ruminants, Mycobacterium avium subsp. paratuberculosis found in wild rabbits, Oryctolagus cuniculus, fecal pellets, urine, field contaminations, 4 farms, rabbit control should be considered as part of a disease control strategies, Scotland, United Kingdom.

Daniels, Mike J.; Lees, Jon D.; Hutchings, Michael R.; Greig, Alastair.  The ranging behaviour and habitat use of rabbits on farmland and their potential role in the epidemiology of paratuberculosis.  Veterinary Journal. 2003; 165(3): 248-257.  ISSN:  1090-0233.  
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=7163&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=f68d9c40dd58509407a11a133122c879
NAL Call No.:  SF601 V484
Descriptors:  rabbits, potential disease reservoir, Mycobacterium avium subsp. paratuberculosis, grazing animals, non-avoidance of rabbit pellets, infected farm study, seasonal effects and spatial differences in rabbit feces deposition, management practices to reduce livestock exposure, Scotland.

Daniels, M.J.; Hutchings, M.R.; Greig, A.  The risk of disease transmission to livestock posed by contamination of farm stored feed by wildlife excreta.  Epidemiology and Infection. 2003; 130(3): 561-568.  ISSN:  0950-2688.  
URL:  http://journals.cambridge.org/action/displayJournal?jid=HYG&bVolume=y
NAL Call No.:  RA651.A1E74
Descriptors:  wild mice and rats, Apodemus sylvaticus, Mus domesticus, Musculus, Rattus novegicus, wild birds, Passer domesticus, Columba livia, pigeons, livestock, cattle, sheep, livestock feed, role of feed contamination by wild animal feces, microbial disease transmission, disease reservoirs, cryptosporidiosis, salmonellosis, Salmonella, Mycobacterium avium subsp. paratuberculosis, infectious probabilities, indications feed is a potential source of the 3 diseases, Scotland, United Kingdom.

De A. Pinto, P.S. Atualizacao em controle da tuberculose no contexto da inspecao de carnes.  [Tuberculosis control update at the meat inspection context.]  Bioscience Journal.  2003; 19(1): 115-121.  ISSN:  1516-3725.  Note:  In Portuguese with an English summary.
NAL Call No.:  QH301.R485
Descriptors: cattle, humans, pigs, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, Mycobacterium bovis, tuberculosis, pathogenecity, lesions, diagnosis, disease control, food safety, meat inspections tuberculosis, zoonotic diseases.

De Lisle, G.W.; Yates, G.F.; Montgomery, R.H.  The emergence of Mycobacterium paratuberculosis in farmed deer in New Zealand - a review of 619 cases.  New Zealand Veterinary Journal.  2003; 51(2): 58-62.  ISSN:  0048-0169.
NAL Call No.:  41.8 N483
Descriptors:  619 deer, 299 farmed deer herds, Mycobacterium avium subsp. paratuberculosis, disease prevalence, epidemiology, case histories, statistics of infection presented, diagnostic techniques, New Zealand.

Denmark Danish Cattle Federation.  Annual Report - Danish Cattle Federation, 2003.  Danish Agricultural Advisory Service, National Centre. Aarhus, Denmark.  2003; 16 p.  
Descriptors:  cattle farming status, marketing, EU reforms, cattle feeding, nutrient standards, feed quality, breeding and breeding value across Nordic Countries, dry periods of dairy cows, housing, welfare, disease prevention, control, monitoring programs, Salmonella Dublin and Mycobacterium avium subsp. paratuberculosis, Denmark.

Deutz, A.; Spergser, J.; Rosengarten, R.; Kofer, J.  Erstnachweis der intrauterinen Ubertragung von Paratuberkulose bei Rot- und Gamswild.  [First detection of intrauterine transmission of paratuberculosis in red deer and chamois.]  Zeitschrift fuer Jagdwissenschaft.  2003; 49(4): 314-319.  ISSN:  0044-2887.  Note:  In German.  
URL:  http://springerlink.metapress.com/(opn50t45wrpt3u55vedijdvb)/app/home/journal.asp?referrer=parent&backto=linkingpublicationresults,1:110828,1
NAL Call No.:  SK351.Z45
Descriptors:  red deer, chamois, paratuberculosis, Mycobacterium avium subsp. paratuberculosis, wild ruminants, intrauterine transmission, disease reservoirs, suckler cow farming, contaminated feed in wildlife feeding, potential control measures, Austria.

Deutz, A.; Spergser, J.; Wagner, P.; Steineck, Th.; Kofer, J.; Rosengarten, R.  Increase of patatuberculosis in wild animal species in Styria.  FEMS Congress of European Microbiologists Abstract Book.  2003; (1): 496.  Note:  1st Federation of European Microbiological Societies (FEMS) Congress of European Microbiologists, Ljubljana, Slovenia; June 29-July 03, 2003.
Descriptors:  wild animal species, mouflon, fallow deer, red deer, row deer, yellow necked mouse, disease surveillance, Mycobacterium avium subsp. paratuberculosis, Styria, Austria.  

Deutz, A.; Spergser, J.; Wagner, P.; Steineck, Th; Koefer, J.; Rosengarten, R.  Paratuberkulose bei Wildtieren: Haeufung klinischer Faelle in freier Wildbahn.  [Paratuberculosis in wild animals: An observed increase in the clinical incidence.] Tieraerztliche Umschau.  2003; 58(9): 482-489.  ISSN:  0049-3864.  Note:  In German with an English summary.  
NAL Call No.:  41.8 T445
Descriptors:  Mycobacterium avium subsp. paratuberculosis, disease incidence, wild animals, red deer, roe deer, chamois, mouflon, fallow deer, yellow necked mouse, factors for increase, potential for improved diagnostic methods, prevention measures, meat hygiene issues, Stryia, South Austria.

Djonne, B.; Jensen, M.R.; Grant, I.R.; Holstad, G.  Detection by immunomagnetic PCR of Mycobacterium avium subsp. paratuberculosis in milk from dairy goats in Norway.  Veterinary Microbiology.  2003; 92(1-2): 135-143.  ISSN:  0378-1135.  
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5190&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=7e99acb030d8f79b52d4e03a1c31a5f8
NAL Call No.:  SF601.V44
Descriptors:  goats, goat milk, Mycobacterium avium subsp. paratuberculosis, subclinical infections, epidemiological surveys, paratuberculosis, PCR, vaccination, Norway.

Djonne, B.; Jensen, M.R.; Grant, I R.; Holstad, G.  Detection of Mycobacterium avium subsp. paratuberculosis in goats milk by immunomagnetic PCR.  FEMS Congress of European Microbiologists Abstract Book.  2003; (1): 453.  Note:  1st Federation of European Microbiological Societies (FEMS) Congress of European Microbiologists, Ljubljana, Slovenia; June 29-July 03, 2003.
Descriptors:  Mycobacterium avium subsp. paratuberculosis, detection method, immunomagnetic PCR, goat’s milk. 

Djonne, B.; Ahrens, P.; Pavlik, I.; Svastova, P.; Holstad, G.  Molecular typing of Mycobacterium avium subsp. paratuberculosis isolated from goats and cattle in Norway.  FEMS Congress of European Microbiologists Abstract Book.  2003; (1): 233.  Note:  1st Federation of European Microbiological Societies (FEMS) Congress of European Microbiologists, Ljubljana, Slovenia; June 29-July 03, 2003.
Descriptors:  cattle, goats, Mycobacterium avium subsp. paratuberculosis, isolate typing, Norway.

Djonne, B.  Paratuberculosis in goats - a special focus on the Nordic countries.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 257-259.  ISSN:  0044-605X.
NAL Call No.:  41.8 AC87
Descriptors:  goats, Johne’s disease, vaccination, animal pathogen, Mycobacterium avium subsp. paratuberculosis, clinical picture, histopathology, diagnosis, disease control and transmission, vaccination, Denmark, Finland, Iceland, Norway, Sweden, Scandanavian.  

Dohmann, K.; Strommenger, B.; Stevenson, K.; Gerlach, G.  Analysis of different Mycobacterium avium ssp. paratuberculosis specific DNA regions in M. avium ssp. paratuberculosis isolates of different host groupings.  Abstracts of the General Meeting of the American Society for Microbiology.  2003; 103: U-061.  ISSN:  1060-2011.  Note:  103rd American Society for Microbiology General Meeting, Washington, DC, USA; May 18-22, 2003.
Descriptors:  Mycobacterium avium subsp. paratuberculosis, DNA analysis of 13 isolates, different host grouping, cattle, sheep, goat, human, PCR, high homology.

Dohmann, K.; Strommenger, B.; Stevenson, K.; de Juan, L.; Stratmann, J.; Kapur, V.; Bull, T.J.; Gerlach, G.F.  Characterization of genetic differences between Mycobacterium avium subsp. paratuberculosis type I and type II isolates.  Journal of Clinical Microbiology.  2003; 41(11): 5215-5223.  ISSN:  0095-1137.
URL:  http://www.pubmedcentral.gov/tocrender.fcgi?action=archive&journal=81
NAL Call No.:  QR46.J6
Descriptors:  cattle, sheep, Mycobacterium avium subsp. paratuberculosis, isolate differences, type I from sheep, type II from cattle, nucleotide sequences, genetic variations, molecular biology, molecular genetics, evolutionary hypothesis.

Englund, Stina.  IS900/ERIC-PCR as a tool to distinguish Mycobacterium avium subsp. paratuberculosis from closely related mycobacteria.  Veterinary Microbiology.  2003; 96(3): 277-287.  ISSN:  0378-1135.  
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5190&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=7e99acb030d8f79b52d4e03a1c31a5f8
NAL Call No.:  SF601.V44
Descriptors:  Mycobacterium avium subsp. paratuberculosis, methods to separate closely related mycobacteria, strain typing, comparison study, rep PCR and conventional RFLP, genetic fingerprints, enterobacterial intergenic consensus (ERIC) sequence, MAP specific insertion sequence IS900, Mycobacterium avium subsp. avium, Mycobacterium intracellulare, other Mycobacterium species.

Ekbom, A.  Paratuberculosis and Crohn's disease - possible linkage?  Acta Veterinaria Scandinavica.  2003; 44(3/4): 267-268.  ISSN:  0044-605X.  
NAL Call No.:  41.8 AC87
Descriptors:  humans, animals, Crohn’s disease, Mycobacterium avium subsp. paratuberculosis, disease prevalence, epidemiology, zoonotic potential, risk factors.

Fischer, O.A.; Matlova, L.; Bartl, J.; Dvorska, L.; Svastova, P.; Du Maine, R.; Melicharek, I.; Bartos, M.; Pavlik, I.  Earthworms (Oligochaeta, Lumbricidae) and mycobacteria.  Veterinary Microbiology.  2003; 91(4): 325-338.  ISSN: 0378-1135.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5190&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=7e99acb030d8f79b52d4e03a1c31a5f8
NAL Call No.:  SF601.V44
Abstract:  The objective of the study was to define the role of earthworms in the survival of mycobacteria in animal populations.  In 13 sampling sites mycobacteria were detected in 53 (5.5%) samples of faeces and parenchymatous tissues from animals, in 25 (7.3%) environmental and in nine (8.2%) earthworm samples.  In cattle and goat farms affected by Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) of IS900 restriction fragment length polymorphism (RFLP) type B-C1 was isolated from 37 (4.6%) faecal samples, three (1.4%) environmental and one (3.1%) earthworm sample.  Investigations of aviaries affected by avian tuberculosis detected M. avium of genotype IS901+ and IS1245+ in six (7.9%) bird's faecal and in four (4.4%) environmental samples. M. avium (genotype IS901- and IS1245+) was detected in four (4.4%) and M. abscessus in one (1.1%) environmental sample.  M. avium of genotype IS901- and IS1245+ and M. gastri were isolated from three (6.4%) earthworm samples.  In pig farm with mycobacteriosis M. avium of genotype IS901- and IS1245+ was detected in five (20.0%) faecal samples from pigs and in four (12.9%) environmental samples.  M. scrofulaceum was isolated in one (4.6%) sample of Lumbricus rubellus.  In laboratory experiments identical RFLP types of M. paratuberculosis were isolated from bodies and faeces of earthworms 1-2 days after the last contact with the faeces contaminated with the same RFLP type of M. paratuberculosis.  The results suggest that earthworms may become vectors of mycobacteria.
Descriptors:  earthworms, disease vectors, Mycobacterium avium subsp. paratuberculosis, mortality, fecal sampling, parenchyma, cattle, goats, pigs, farms, RFLP, Mycobacterium avium, contamination, Mycobacterium abscessus, Mycobacterium gastri, Mycobacterium scrofulaceum.

Fischer, O.A.; Matlova, L.; Dvorska, L.; Svastova, P.; Pavlik, I.   Nymphs of the Oriental cockroach (Blatta orientalis) as passive vectors of causal agents of avian tuberculosis and paratuberculosis.  Medical and Veterinary Entomology.  2003; 17(2): 145-150.  ISSN:  0269-283X.
URL:  http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=mve
NAL Call No.:  RA639.M44
Descriptors:  Mycobacterium avium, Mycobacterium avium subsp paratuberculosis, disease vectors, Blatta orientalis, Oriental cockroach nymphs, experimental oral infection, isolated pathogens via RFLP, nymphs can have and shed viable and virulent mycobacteria, Czech Republic.

Fredriksen, B.; Jarp, J.  Factors affecting the herd level of antibodies against Mycobacterium avium subsp. paratuberculosis - a case-control study.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 283.  ISSN:  0044-605X.  
NAL Call No.:  41.8 AC87
Descriptors:  dairy cattle, dairy herds, antibody survey, Johne’s disease prevalence, disease transmission, epidemiology, wild animals as disease reservoirs, risk factors, Norway.

Fridriksdottir, V.; Gunnarsson, E.; Sigurdarson, S.; Gudmundsdottir, K.B.  Paratuberculosis in Iceland - ongoing research.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 273.  ISSN:  0044-605X.  
NAL Call No.:  41.8 AC87
Descriptors:  cattle, sheep, Mycobacterium avium subsp. paratuberculosis, Johne’s disease research program, disease control, diagnostic techniques.

Fus, M.M.; Szteyn, J.; Wiszniewska, A.; Herman, L.  Comparison of three methods of releasing DNA from Mycobacterium avium subsp. paratuberculosis cells.  Bulletin of the Veterinary Institute in Puawy.  2003; 47(1): 107-112.  ISSN:  0042-4870.
Descriptors:  Mycobacterium avium subsp. paratuberculosis, DNA release methods, cell wall lysis, SDS, NaOH, sodium hydroxide, high and low temperatures, mini-bead beater.

Grant, I.R.; Kirk, R.B.; Hitchings, E.; Rowe, M.T.  Comparative evaluation of the MGITTM and BACTEC culture systems for the recovery of Mycobacterium avium subsp. paratuberculosis from milk.  Journal of Applied Microbiology.  2003; 95(1): 196-201.  ISSN:  1364-5072.
URL:  http://www.blackwellpublishing.com/journal.asp?ref=1364-5072
Descriptors:  Mycobacterium avium subsp. paratuberculosis, spiked milk, testing for bacterial contamination, methods, Mycobacterium Growth Indicator Tubes, MGITTM, BACTEC460TB culture system, detection comparison, culture media.

Grant, I.R.  Mycobacterium paratuberculosis and milk.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 261-266.  ISSN:  0044-605X.
NAL Call No.:  41.8 AC87
Descriptors:  cattle, humans, Mycobacterium avium subsp. paratuberculosis contaminated milk, research on the risk of transfer to humans, milk testing, bacterial can survive pasteurization, raw and commercial milk can be source of Mycobacterium avium subsp. paratuberculosi.

Groenendaal, H.  Controlling Johne's disease: results of computer modelling.  Cattle Practice.  2003; 11(4): 219-225.  ISSN:  0969-1251.
NAL Call No.:  SF961.C37
Descriptors:  dairy cattle, Mycobacterium avium subsp. paratuberculosis, "JohneSSim model" computer simulation model, evaluates economic and epidemiological 3 disease control strategies, 1) test and cull, 2) calf hygiene management, 3) vaccination, The Netherlands, United States.

Groenendaal, Huybert; Galligan, David T.  Economic consequences of control programs for paratuberculosis in midsize dairy farms in the United States.  Journal of the American Veterinary Medical Association.  2003; 223(12): 1757-1763.  ISSN:  0003-1488.
NAL Call No.:  41.8 AM3
Descriptors:  dairy herds, dairy farms, Mycobacterium avium subsp. paratuberculosis, disease prevalence, control programs, epidemiology, vaccination, paratuberculosis simulation models, vaccination.

Groenendaal, Huybert; Nielen, Mirjam; Hesselink, Jan Willem.  Development of the Dutch Johne's disease control program supported by a simulation model.  Preventive Veterinary Medicine.  2003; 60(1): 69-90.  ISSN:  0167-5877.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5145&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=c5bc3d9e1bb66468352ae1f5475d522f
NAL Call No.:  SF601.P7
Descriptors:  dairy cattle herds, beef cattle herds, Mycobacterium avium subsp. paratuberculosis, disease control, simulation model—JohneSSim, test and cull strategies, not economical, improved calf hygiene management, Paratuberculosis Program Netherlands (PPN), The Netherlands.

Gunnarsson, E.; Fridriksdottir, V.; Sigurdarson, S.  Control of paratuberculosis in Iceland.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 255.  ISSN:  0044-605X.  
NAL Call No.:  41.8 AC87        
Descriptors:  cattle, sheep, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, diagnosis, mortality, disease prevalence, prevention, vaccination, disease transmission, Iceland.

Hanson, Timothy E.; Johnson, Wesley O.; Gardner, Ian A.; Georgiadis, Marios P.  Determining the infection status of a herd.  Journal of Agricultural Biological and Environmental Statistics.  2003; 8(4): 469-485.  ISSN:  1085-7117.
NAL Call No.:  S566.55.J68
Descriptors:  dairy herds, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, disease prevalence, hierarchical model, hypergeometric or binomial sample, animal screening data, variables, infection status of herd, diagnostic test accuracy, herd prevalence.

Hendrick, S.; Duffield, T.; Kelton, D.; Leslie, K.; Lissemore, K.; Archambault, M.  A relative comparison of diagnostic tests for Johne's disease.  Journal of Dairy Science.  2003; 86(Suppl. 1): 84-85.  ISSN:  0022-0302.  Note:  Joint Annual Meeting of the American Dairy Science Association, the American Society of Animal Science and the Mexican Association of Animal Production, Phoenix, Arizona, USA; June 22-26, 2003.
URL:  http://jds.fass.org/contents-by-date.0.shtml
NAL Call No.:  44.8 J822
Descriptors:  cattle, Johne’s disease, diagnostic tests, comparison study.  

Hickey, S M.; Morris, C.A.; Dobbie, J.L.; Lake, D.E.  Heritability of Johne's disease and survival data from Romney and Merino sheep.  Proceedings of the New Zealand Society of Animal Production.  2003; 63: 179-182.  ISSN:  0370-2731.
NAL Call No.:  49.9 N483
Descriptors:  Mycobacterium avium subsp. paratuberculosis, Merino sheep breed, Romney sheep breed, heritability of disease resistance, Johne’s disease susceptibility, quantitative genetics, not a very viable approach, AgResearch's Tokanui Station, New Zealand.

Hill, B.B.; West, M.; Brock, K.V.  An estimated prevalence of Johne's disease in a subpopulation of Alabama beef cattle.  Journal of Veterinary Diagnostic Investigation.  2003; 15(1): 21-25.  ISSN:  1040-6387.
NAL Call No.:  SF774.J68
Descriptors:  beef cattle, estimate the overall prevalence of animals infected with Mycobacterium avium subsp. paratuberculosis, antibody testing of sera, 79 beef herds in Alabama Brucellosis Certification program, ELISA test, disease prevalence, disease surveys, 50% of the herds infected with MAP, overall prevalence of 8%, Alabama, United States. 

Hines, Murray E. II.  Preliminary characterization of chemically generated Mycobacterium avium subsp. paratuberculosis cell wall deficient forms (spheroplasts).  Veterinary Microbiology.  2003; 95(4): 247-258.  ISSN:  0378-1135.
URL: http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5190&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=7e99acb030d8f79b52d4e03a1c31a5f8
NAL Call No.:  SF601.V44
Descriptors:  Mycobacterium avium subsp. paratuberculosis, cell wall deficient forms, Crohn's disease, humans, immune response, pathogenesis, ultrastructure, Johne’s disease, cattle.

Holliman, A.  Restocking problems post-FMD.  Cattle Practice.  2003; 11(4): 311-312.  ISSN:  0969-1251.
NAL Call No.:  SF961.C37
Descriptors:  cattle, restocking after depopulations due to FMD, importation of heifers, disease transmission from outside, lack of biosecurity to prevent diseases transferred, tuberculosis, BVD, IBR, Johne’s disease, United Kingdom.

Holmstrom, A.; Kyhlstedt, U.; Robertsson, J.A.; Stengarde, L.  Control of paratuberculosis in Sweden.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 285-286.  ISSN:  0044-605X.  
NAL Call No.:  41.8 AC87
Descriptors:  beef cattle, Johne’s control programs, disease prevalence, Sweden.

Holstad, G.; Sigurdardottir, O.; Valheim, M.; Storset, A.; Olsen, L.; Halldorsdottir, S.; Djonne, B.; Fredriksen, B.  Mycobacterium avium subspecies paratuberculosis - a review of present research in Norway.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 269-272.  ISSN:  0044-605X.  
NAL Call No.:  41.8 AC87
Descriptors:  cattle, goats, sheep, Johne’s disease, Mycobacterium avium subsp. paratuberculosis, animal disease research, epidemiology, disease transmission, diagnostics, Johne’s disease research in Norway.

Horwood, P.; McGowan, M.; Orpin, P.; Thompson, I.; Brownlie, J.  Evaluation of two ELISA's for the detection of Mycobacterium avium paratuberculosis antibodies in milk samples from dairy cattle.  Cattle Practice.  2003; 11(3): 147-149.  ISSN:  0969-1251.
NAL Call No.:  SF961.C37
Descriptors:  dairy cattle, Johne’s disease, Mycobacterium avium subsp. paratuberculosis, identify an accurate and cost effective test, comparing testing sera and milk, available ELISA assays, United Kingdom.

Hostetter, J.; Steadham, E.; Haynes, J.; Bailey, T.; Cheville, N.  Phagosomal maturation and intracellular survival of Mycobacterium avium subspecies paratuberculosis in J774 cells.  Comparative Immunology Microbiology and Infectious Diseases.  2003; 26(4): 269-283.  ISSN:  1085-7117.
URL:    http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5003&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=d84c7d4df471489f36fcab6d30fb7920
NAL Call No.:  QR180.C62
Descriptors:  Mycobacterium avium subsp. paratuberculosis, Mycobacterium smegmatis, inhibition of phagosomal maturation, bacteria reside in phagosomal component of non-mature phagolysome, macrophages, surface proteins, bacterial survival, transferring, zymosan.

Huda, A.; Lind P.; Christoffersen, A.B.; Jungersen, G.  Analysis of repeated tests for interferon-gamma (IFN-gamma) response and faecal excretion for diagnosis of subclinical paratuberculosis in Danish cattle.  Veterinary Immunology and Immunopathology.  2003; 94(3-4): 95-103.  ISSN:  0165-2427.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5189&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=f5f60e05fe0e447c7311059c14754776
NAL Call No.:  SF757.2.V38
Descriptors:  425 dairy cattle, 10 infected and 5 non-infected dairy herds, Mycobacterium avium subsp. paratuberculosis, 3 consecutive samplings, whole blood, fecal culture, diagnosis, diagnostic techniques, INF-gamma, IDEXX-criteria, recommendations for test use and sensitivity, interferon, paratuberculosis, Denmark.

Huda, A.; Jensen, H.E.  Comparison of histopathology, cultivation of tissues and rectal contents, and interferon-gamma and serum antibody responses for the diagnosis of bovine paratuberculosis.  Journal of Comparative Pathology.  2003; 129(4): 259-267.  ISSN:  0021-9975.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=6861&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=6091bef4d15aae1adbceffba708c6eb8
NAL Call No.:  41.8 J82
Descriptors:  cattle, infected and non-infected dairy herds, Mycobacterium avium subsp. paratuberculosis, immune response, interferon, antibodies, diagnosis, diagnostic techniques, histopathology of tissues, culture of serial rectal contents, testing blood for IFN gamma and antibody responses, large intestine, small intestine tissue samples, mesemteric lymph nodes, pharyngeal tonsil, retropharyngeal, mediastinal, hepatic and supramammary lymphoid sampling, lymphnodes draining jejunum, tissue culture.

Huda, A.; Jungersen, G.; Christoffersen, A.B.; Lind, P.  Diagnosis of bovine paratuberculosis by interferon-gamma (IFN- gamma ) test.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 281.  ISSN:  0044-605X.  
NAL Call No.:  41.8 AC87
Descriptors:  cattle, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, diagnosis with interferon-gamma, immunodiagnosis.

Inglis, Neil F.; Stevenson, Karen; Heaslip, Darragh G.; Sharp, J. Michael.  Characterisation of IS901 integration sites in the Mycobacterium avium genome.  FEMS Microbiology Letters.  2003; 221(1): 39-47.  ISSN:  0378-1097.
URL:  http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=fml
NAL Call No.:  QR1.F44
Descriptors:  Mycobacterium avium, strains, cervine strain JD88/118 and IS901, identification and characterization, 17 chromosomal integration loci of element IS901, IS900, IS901 inserts preferentially between a putative ribosome-binding sequence (RBS) and translational start codon of an open reading frame (ORF).

Jessep, T.  Keeping bovine Johne's off your property.  Agnote NSW Agriculture.  2003; (DAI-50 (2nd Edition)): 1-4.  ISSN:  1034-6848.
Descriptors:  cattle, Mycobacterium avium subsp. paratuberculosis, disease prevention and control, New South Wales, Australia.

Jungersen, G.  Infektionsforlob og immunologisk diagnostik ved paratuberkulose.  [The course of infection and the immunological diagnosis of paratuberculosis.]  Dansk Veterinaertidsskrift.  2003; 86(4): 6-10.  ISSN:  0106-6854.  Note:  In Danish.  
Descriptors:  cattle, Mycobacterium avium subsp. paratuberculosis, symptoms, 5 stages of course of infection outlined, immune response, immunological techniques, diagnosis, diagnostic tests for different for each stage of the disease, bacteria in feces, antibodies in blood serum, measurement cell mediated immune response, interferon-gamma test for screening, ELISA rapid indication of defective immune response.

Jungersen, G.  Ongoing research on paratuberculosis in Denmark 2001.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 279-280.  ISSN:  0044-605X.  
NAL Call No.:  41.8 AC87
Descriptors:  cattle, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, pathogenesis, epidemiology, diagnostic related research, disease prevalence, disease transmission, research programs, Denmark.

Kalis, C.H.J.; Collins, M.T.; Hesselink, J.W.; Barkema, H.W.  Specificity of two tests for the early diagnosis of bovine paratuberculosis based on cell-mediated immunity: the Johnin skin test and the gamma interferon assay.  Veterinary Microbiology.  2003; 97(1/2): 73-86.  ISSN:  0378-1135.  
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5190&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=7e99acb030d8f79b52d4e03a1c31a5f8
NAL Call No.:  SF601.V44
Descriptors:  dairy cows, Mycobacterium avium subsp. paratuberculosis, assays for cell mediated immunity, looking for early diagnosis, Johnin skin test, IFN gamma test, diagnostic tests.

Kennedy, James A.  Methodology and Computer Modeling of Pooled Fecal Cultures to Determine Herd Status of Johne's Disease in Beef Cattle.  2003; viii, 60 p., ill.  Note:  Thesis (M.S.).  University of Nebraska, Lincoln, Nebraska.
Descriptors:  Mycobacterium avium subsp. paratuberculosis, beef cattle, disease status of herd, pooled fecal cultures, computer model, methods, Nebraska.

Khare, S.; Zhang, S.; Nunes, J.E.S.; Figueiredo, J.F.; Ficht, T.A.; Rice-Ficht, A.C.; Adams, L.G.  Bovine ligated ileal loop infected with Mycobacteium avium subspecies paratuberculosis: Ultrastructural analysis of Peyer's patches and early changes in gene expression profiles of C-C cytokines and C-X-C cytokine.  Abstracts of the General Meeting of the American Society for Microbiology.  2003; 103: Z-007.  ISSN:  1060-2011.  Note:  103rd American Society for Microbiology General Meeting, Washington, DC, USA; May 18-22, 2003.
Descriptors:  cattle, Mycobacterium avium subsp. paratuberculosis, interaction between intestinal mucus and pathogen, bovine ligated ileal, injected with live pathogen, pathogen uptake, times sampling post infection, real time PCR, invasion of Peyer’s patches.

Klausen, Joan; Huda, Anna; Ekeroth, Lars; Ahrens, Peter.  Evaluation of serum and milk ELISAs for paratuberculosis in Danish dairy cattle.  Preventive Veterinary Medicine.  2003; 58(3-4): 171-178.  ISSN:  0167-5877.  
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5145&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=c5bc3d9e1bb66468352ae1f5475d522f
NAL Call No.:  SF601.P7
Descriptors:  580 dairy cows, 6 dairy herds with MAP, 2 dairy herds negative for Johne’s disease, Mycobacterium avium subsp. paratuberculosis, blood serum sampling, milk comparison study, diagnostic methods, analytical methods, antibody testing, ELISA and complement fixation tests, fecal sample culture, disease prevalence, immunological techniques, paratuberculosis.

Kruip, T.A.M.; Muskens, J.; van Roermund, H.J.W.; Bakker, D.; Stockhofe-Zurwieden, N.  Lack of association of Mycobacterium avium subsp. paratuberculosis with oocytes and embryos from moderate shedders of the pathogen.  Theriogenology.  2003; 59 (7): 1651-1660.  ISSN: 0093-691X.
NAL Call No.:  QP251.A1T5
Abstract:  Paratuberculosis is a chronic and progressive disease of the intestine in ruminants caused by Mycobacterium avium subsp. paratuberculosis (Map).  The bacterium is transmitted to young animals, becomes manifest in adulthood and leads to economic losses.  The aim of this study is to investigate if cows shedding Map possess oocytes and embryos that are carriers of the bacterium.  New genetical material can enter the dairy farm using embryo transfer but the question as to whether this technique is safe with respect to transmission of paratuberculosis has yet to be addressed.  We selected and bought 16 cows, all proven to be moderate shedders of the bacterium in the faeces immediately prior to the experiment but none were clinically sick.  One sample of uterine content was collected from each animal by flushing the uterus on the day of heat and five samples of homogenised uterine tissue were collected on the eighth day of the same cycle by biopsy.  In addition, 217 cumulus-oocyte complexes (COCs), ranging from 3 to 35 COCs per animal, were collected using ultrasound guided transvaginal puncture of the ovarian follicles (OPU).  On the seventh day of the subsequent cycle 31 embryos were obtained using the classic technique of super ovulation induction, artificial insemination (AI), followed by flushing of the uterus.  These embryos have been washed and trypsinised.  Fourteen of the 16 cows were treated again for super ovulation in the subsequent cycle and 19 foetuses were collected by opening of the uterus after euthanasia on Days 35-49 of the cycle.  All samples were cultured for presence of Map and checked every 2 months during 1 year for bacterial growth.  None of the samples showed growth of Map after 12 months of culture.  Pathological examination of the cows revealed different degrees of severity of pathological alterations of the intestinal tract and mesenteric lymph nodes. However, the results suggest that neither in vivo embryo's nor oocytes are carriers of the bacteria and do not form an extra risk at transfer.  However, due to the limited size of the experiment (sample size of 16 cows), a certain margin for error remains.
Descriptors:  dairy cows, paratuberculosis, Mycobacterium avium subsp. paratuberculosis, chronic diseases, disease transmission  transplacental transmission, embryo transfer, superovulation, embryo animal, cell culture, lymphadenitis, enteritis, histopathology, disease course, cattle diseases, vertical transmission, embryo donors, The =Netherlands.

Kudahl, A.; Nielsen, S.S.; Sorensen, J.T.  Effects of paratuberculosis on productivity in Danish dairy cows.  Acta Veterinaria Scandinavica Supplementum. 2003; (suppl. 98): 274.  ISSN: 0065-1699.  Note.  J.F. Agger and N. Toft edited the special issue. 
Descriptors:  dairy cows, effects of Johne’s disease, Mycobacterium avium subsp. paratuberculosis, age at first calving, lactation, milk yields, protein content, culling, slaughter weights, Denmark.

Lage, Susanne Zur; Goethe, Ralph; Darji, Ayub; Valentin Weigand, Peter; Weiss, Siegfried.  Activation of macrophages and interference with CD4+ T-cell stimulation by Mycobacterium avium subspecies paratuberculosis and Mycobacterium avium subspecies avium.  Immunology.  2003; 108(1): 62-69.  ISSN:  0019-2805.
URL:  http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=imm
NAL Call No.:  448.3 IM6:
Descriptors:  mice, animal disease model, Mycobacterium avium subsp. paratuberculosis, Mycobacterium avium subsp. avium, macrophages, CD4+ T lymphocytes, cytokines, disease models, immune response, major histocompatibility complex.

Lillini, E.; Macri, G.; Fagiolo, A.; Cersini, A.  Efficiency of laboratory methods in a bovine herd affected by Johne's disease.  In:  Thanawongnuwech, R.; Ingkaninun, P. [Editors]  Proceedings 11th International Symposium of the World Association of Veterinary Laboratory Diagnosticians and OIE Seminar on Biotechnology, Bangkok, Thailand, 9-13 November, 2003.  Published by the Thai Veterinary Medical Association.  Bangkok.  2003; O36-O37.  ISBN:  9741325894.
Descriptors:  Mycobacterium avium subsp. paratuberculosis, diagnosis, efficiency of diagnostic techniques, disease prevalence, epidemiology, immunological techniques, PCR, Italy.  

Lesser, A.  Paratuberkulose: Ein weit verbreitetes Problem in Rinderbestnden.  [Paratuberculosis. A very widespread problem in dairy herds.]  Milchpraxis.  2003; 41(4): 172-175.  ISSN:  0343-0200.  Note:  In German.  
NAL Call No.:  SF221 M5
Descriptors:  dairy calves, neonates, dairy cows, colostral immunity, Mycobacterium avium subsp. paratuberculosis, disease prevention, disease prevalence, Germany.

Lipiec, Marek.  Paratuberkuloza jako zoonoza.  [Paratuberculosis as a zoonosis.] Medycyna Weterynaryjna.  2003; 59(3): 191-194.  ISSN:  0025-8628.  Note:  In Polish.
NAL Call No.:  41.8 M463
Descriptors:  Mycobacterium avium subsp. paratuberculosis, potential as a zoonotic disease via contaminated milk and milk products, Crohn's disease, humans, review. 

Lucas, J.N.; Cousins, D.V.; Mills, A.J.; Van Wijk, J.G.A.  Identification of Mycobacterium avium subsp avium in an alpaca with lesions resembling paratuberculosis.  Australian Veterinary Journal.  2003; 81(9): 567-569.  ISSN:  0005-0423.
URL:  http://www.ava.com.au/avjpast.php?journalid=9&plink=avj03.htm
NAL Call No.:  41.8 AU72
Descriptors:  alpacas, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, case reports, clinical aspects, diagnosis, identification, histopathology, paratuberculosis.

Mackintosh, C.G.; Wilson, P.R.  Impact of diseases on the NZ deer industry.  Proceedings of the New Zealand Society of Animal Production.  2003; 63: 262-268.  ISSN:  0370-2731.
NAL Call No.:  49.9 N483
Descriptors:  deer farming, farmed deer industry, economic impacts of diseases, animal health care costs, clinical and subclinical disease states, disease control and prevention, better disease screening technologies, nutritional deficiencies and toxicities, bacterial diseases, leptospirosis, malignant catarrhal fever, nematode parasites, bovine tuberculosis, Johne’s disease, New Zealand.

Manning, Elizabeth J.B.; Augenstein, Monica; Collins, Michael T.; Nelson, Kathryn M.  Case report: Johne's disease: The recipient risk.  Bovine Practitioner.  2003; 37(1): 20-22.  ISSN:  0524-1685.  Note:  In English with a French summary.
NAL Call No.:  SF779.5.A1B6
Descriptors:  calves, cows, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, embryo transfer, intrauterine transmission, became test positive during pregnancy, calf diagnosed 2 years later, no postnatal exposure, vertical transmission concerns, case reports, Wisconsin, United States.

Manning, E.J.B.; Steinberg, H.; Krebs, V.; Collins, M.T.  Diagnostic testing patterns of natural Mycobacterium paratuberculosis infection in pygmy goats.  Canadian Journal of Veterinary Research.  2003; 67(3): 213-218.  ISSN:  0830-9000.  Notes:  In English with a French summary.  
URL:  http://www.pubmedcentral.gov/tocrender.fcgi?action=archive&journal=133
NAL Call No.:  SF601.C24
Descriptors:  13 pigmy goats, Capra hircus, naturally infected herd, Mycobacterium avium subsp. paratuberculosis, 4 diagnostic assays, gamma interferon (IFN gamma), serum antibody ELISA and agar gel diffusion (AGID), radiometric fecal culture, tissues collected at necropsy, isolates confirmed with IS900 PCR, false positives and false negatives, need to use multiple tests.

Manning, Elizabeth J.B.; Kucera, Thomas E.; Gates, Natalie B.; Woods, Leslie M.; Fallon McKnight, Maura.  Testing for Mycobacterium avium subsp. paratuberculosis infection in asymptomatic free-ranging tule elk from an infected herd.  Journal of Wildlife Diseases.  2003; 39(2): 323-328.  ISSN:  0090-3558.
URL:  http://www.jwildlifedis.org/
NAL Call No.:  41.9 W64B
Descriptors:  45 tule elk, free ranging asymptomic animals, Cervus elaphus nannodes, Mycobacterium avium subsp. paratuberculosis, ELISA, agar gel immunodiffusion assay (AGID), fecal culture, 22 elk showed MAP, 10 of 22 euthanazed animals had histopathologic lesions, immunodiffusion, Point Reyes National Seashore, Marin County, California, United States.

Mercier, P.  Sante: la paratuberculose caprine.  [Paratuberculosis in goats.]  Chevre.  2003; (254): 30-31.  ISSN:  0045-6608.  Note:  In French.
Descriptors:  goats, Johne’s disease, Mycobacterium avium subsp. paratuberculosis, symptoms, lesions, bacteriology, epidemiology, economic costs, methods of reducing incidence, culling of sick animals, separation of kids, disinfection of buildings and pastures.

Mork, Tormod; Heier, Berit Tafjord; Alvseike, Kristin Ruud; Lund, Arve.  Overvakings- og kontrollprogrammer for landdyr, fisk og skjell i Norge med vekt pa BSE, salmonella, og paratuberkuloseprogrammene.  [Surveillance and control programs for terrestrial and aquatic animals in Norway for BSE, salmonella, and paratuberculosis.]  Norsk Veterinaertidsskrift.  2003; 115(11): 707-717.  ISSN:  0332-5741.  Note:  In Norwegian
Descriptors:  terrestrial and aquatic animals, bovine spongiform encephalopathy, BSE, Mycobacterium avium subsp. paratuberculosis, Salmonella, disease control, epidemiological surveys, Norway.

Morris, C.A.; Hickey, S.M.; Dobbie, J.L.; Lake, D.E.  A breed difference between Romneys and Merinos in the incidence of Johne's disease on a New Zealand farm.  50 Years of DNA: Proceedings of the Fifteenth Conference, Association for the Advancement of Animal Breeding and Genetics, Melbourne, Australia, 7-11 July 2003.  2003: 399.  ISBN:  0958629927.
Descriptors:  sheep breeds, Romneys, Merinos, breed differences, crossbreds, disease prevalence of Johne’s disease, epidemiology, New Zealand.

Motiwala, A.S.; Strother, M.; Amonsin, A.; Byrum, B.; Naser, S.A.; Stabel, J.R.; Shulaw, W.P.; Bannantine, J.P.; Kapur, V.; Sreevatsan, S.  Molecular epidemiology of Mycobacterium avium subsp. paratuberculosis: evidence for limited strain diversity, strain sharing, and identification of unique targets for diagnosis.  Journal of Clinical Microbiology.  2003; 41(5): 2015-2026.  ISSN:  0095-1137.  
URL:  http://www.pubmedcentral.gov/tocrender.fcgi?iid=4818
NAL Call No.:  QR46.J6
Descriptors:  Mycobacterium avium subsp. paratuberculosis, molecular diversity of animal and human strains, US isolates, sheep, cows, Johne’s disease (203 isolates), human Crohn’s disease (7 isolates), searching for specific diagnostic molecular markers, multiplex PCR of IS900 integration loci (MPIL) and amplified fragment length polymorphism (AFLP) analyses, DNA fingerprinting, identified a high degree of genetic similarity between cow strains, relatively higher degree of genetic heterogeneity among human and ovine strains.

Motiwala, A.S.; Strother, M.; Manning, E.; Sreevatsan, S.  Restricted diversity within Mycobacterium avium subsp. paratuberculosis isolated from exotic animal species from diverse geographic locations.  Abstracts of the General Meeting of the American Society for Microbiology.  2003; 103: U 039.  ISSN:  1060-2011.  Note:  103rd American Society for Microbiology General Meeting, Washington, DC, USA; May 18-22, 2003.
Descriptors:  cattle, captive and free ranging wildlife, bison, duiker, elk, gnu, nyala, impala, and oryx, survey, Mycobacterium avium subsp. paratuberculosis, Mycobacterium avium subsp. avium, radiometric culture of fecal and tissue samples, 16 isolates, ATCC19698, broth cultures, DNA molecular markers, IS900, Mycobacterium avium subsp. paratuberculosis locus 251, HSP 65, IS1311, restriction endomuclease analyses, single monomorphic clone of Mycobacterium avium subsp. paratuberculosis widespread dissemination for cross species, United States.

Muehlherr, J.E.; Zweifel, C.; Corti, S.; Blanco, J.E.; Stephan, R.  Microbiological quality of raw goat's and ewe's bulk-tank milk in Switzerland.  Journal of Dairy Science.  2003; 86(12): 3849-3856.  ISSN:  0022-0302.  
URL:  http://jds.fass.org/contents-by-date.0.shtml
NAL Call No.:  44.8 J822
Descriptors:  dairy goats, dairy sheep, testing raw bulk milk, plate counts, Enterobacteriaceae counts, Staphylococcus aureus, Campylobacter spp., Shiga toxin producing Escherichia coli, Salmonella spp., and Mycobacterium avium subsp. paratuberculosis, risk assessment program for milk from small ruminants, Switzerland.

Mullerad, J.; Hovav, A.H.; Nahary, R.; Fishman, Y.; Bercovier, H.  Immunogenicity of a 16.7 kDa Mycobacterium paratuberculosis antigen.  Microbial Pathogenesis.  2003; 34(2): 81-90.  ISSN:  0882-4010.  
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=6954&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=0ce0cc81f81ede9640040947d652abf1
NAL Call No.:  QR175.M53
Descriptors:  mice as laboratory animal models, Mycobacterium avium subsp. paratuberculosis, adjuvants, immune response, interferon, antigens biochemistry, delayed type hypersensitivity, vaccination, immunization interleukin 10, interleukin 6, nitric oxide, oxidoreductases, peroxidases, splenocytes.

Muskens, J.; Elbers, A.R.W.; van Weering, H.J.; Noordhuizen, J.P.T.M.  Herd management practices associated with paratuberculosis seroprevalence in Dutch dairy herds.  Journal of Veterinary Medicine Series B.  2003; 50(8): 372-377.  ISSN:  0931-1793
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0931-1793&site=1
NAL Call No.:  41.8 Z52
Descriptors:  dairy cows, 370 dairy herds, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, epidemiology, disease prevention and control, management practices, questionnaire study, risk factors, serological surveys, seroprevalence, comparison between seropostive and seronegative herds, The Netherlands.

Muskens, J.; Mars, M.H.; Elbers, A.R.W.; van Maanen, K.; Bakker, D.  The results of using faecal culture as confirmation test of paratuberculosis-seropositive dairy cattle.  Journal of Veterinary Medicine Series B.  2003; 50(5): 231-234.  ISSN:  0931-1793.
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0931-1793&site=1
NAL Call No.:  41.8 Z52
Descriptors:  15,822 dairy cattle, 378 herds, ELISA, Mycobacterium avium subsp. paratuberculosis, ages 3-6 year, age differences, confirmatory tests, fecal culture, disease control and prevention, serology, vaccination.

National Research Council (U.S.) Committee on Diagnosis and Control of Johne's Disease. Diagnosis and Control of Johne's Disease.  National Academies Press, Washington, DC. c2003; xiv, 229 p., ill.  ISBN: 0309086116; 030950628X (PDF)
URL:  http://www.nap.edu/books/0309086116/html/
NAL Call No.:  SF809.P375 D52 2003
Descriptors:  diagnosis, paratuberculosis, treatment, Mycobacterium avium subsp. paratuberculosis, various methodologies.

Nielsen, S.S.; Toft, N.; Houe, H.; Enevoldsen, C.  Paratuberkulose som sandsynlighedsdiagnose - Brug af diagnoser - simple go komplekse.  [Probability diagnosis of paratuberculosis: use in diagnosis - simple or complex.]  Dansk Veterinaertidsskrift.  2003; 86(8): 6-10.  ISSN:  0106-6854.  Note:  In Danish with an English summary.  
Descriptors:  cattle, Mycobacterium avium subsp. paratuberculosis, diagnostic techniques, Johne’s disease, decision support system for diagnosis of complex disease, computer model, animal characteristics.

Nielsen, S.S.  Possibilities for intervention against paratuberculosis in Danish dairy herds.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 289-290.  ISSN:  0044-605X.
NAL Call No.:  41.8 AC87
Descriptors:  dairy cattle, dairy herds, ELISA diagnostic techniques, Mycobacterium avium subsp. paratuberculosis, disease control programs, disease prevention, Denmark.

Nielsen, S.S.; Agger, J.F.  Comparison of milk and serum enzyme-linked immunosorbent assays adjusted for time-related factors for the detection of paratuberculosis in dairy cattle.  Acta Veterinaria Scandinavica, Supplementum.  2003; (Suppl. 98): 239.  ISSN:  0065-1699.  Note:  J.F. Agger and N. Toft edited the special issue.
NAL Call No.:  41.8 AC87 Suppl.
Descriptors:  dairy cattle, Johne’s disease, antibodies, milk, diagnosis, Mycobacterium avium subsp. paratuberculosis, diagnostic techniques, ELISA, immune serum.

Olsen, I.; Johansen, T.B.; Bilman-Jacobe, H.; Nilsen, S.F.; Djonne, B.  A novel IS element, ISMpa1, in Mycobacterium avium subsp. paratuberculosis.  FEMS Congress of European Microbiologists Abstract Book.  2003; (1): 60.  Note:  1st Federation of European Microbiological Societies (FEMS) Congress of European Microbiologists, Ljubljana, Slovenia; June 29-July 03, 2003.  
Descriptors:  Mycobacterium avium subsp. paratuberculosis, IS element, ISMpal.

Ostrowski, M.; Mundo, S.L.; Harris, N.B.; Barletta, R,G.; Lopez, O.J.  B-cell epitopes in the immunodominant p34 antigen of Mycobacterium avium ssp. paratuberculosis recognized by antibodies from infected cattle.  Scandinavian Journal of Immunology.  2003; 58(5): 511-521.  ISSN:  0300-9475.   
URL:  http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=sji
NAL Call No.:  QR180.S3
Descriptors:  cattle, infected animals, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, immune response, antigens, bacteriophages, amino acid sequences, antibodies, B lymphocytes epitopes, immune response, peptides, surface protein p34, T helper 1 (Th1) to a Th2 profile.

Ozbek, Ahmet; Michel, Frederick C. Jr. ; Strother, Megan; Motiwala, Alifiya S.; Byrum, Beverly R.; Shulaw, William P.; Thornton, Charles G.; Sreevatsan, Srinand.  Evaluation of two recovery methods for detection of Mycobacterium avium subsp. paratuberculosis by PCR: Direct-dilution-centrifugation and C18-carboxypropylbetaine processing.  FEMS Microbiology Letters.  2003; 229(2): 145-151.  ISSN:  0378-1097.  
URL:  http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=fml
NAL Call No.:  QR1.F44
Descriptors: :  cattle, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, assays, diagnostic assays, asymptomatic infections, PCR, IS900 integration sites, feces sampling, 2 recovery methods, direct dilution centrifugation method, C18 carboxypropylbetaine (CB-18) based method, sensitive for subclinical animals, diagnosis, diagnostic techniques.

Pak, S.I.; Kim, D.; Salman, M.  Estimation of paratuberculosis prevalence in dairy cattle in a province of Korea using an enzyme-linked immunosorbent assay: application of Bayesian approach.  Journal of Veterinary Science.  2003; 4(1): 51-56.  ISSN: 1229-845X.
URL:  http://www.ksvs.or.kr
NAL Call No.:  SF604.J68
Descriptors:  dairy cows, cattle diseases, paratuberculosis, Mycobacterium avium subsp. paratuberculosis, bacterial infections, disease prevalence, screening, antibody detection, disease detection, ELISA, epitopes, recombinant proteins, accuracy, statistical analysis, Bayesian theory, Korea Republic.

Paolicchi, F.A.; Zumarraga, M.J.; Gioffre, A.; Zamorano, P.; Morsella, C.; Verna, A.; Cataldi, A.; Alito, A.; Romano, M.  Application of different methods for the diagnosis of paratuberculosis in a dairy cattle herd in Argentina.  Journal of Veterinary Medicine Series B.  2003; 50(1): 20-26.  ISSN:  0931-1793.
URL:  http://www.blackwellpublishing.com/journal.asp?ref=0931-1793&site=1
NAL Call No.:  41.8 Z52
Descriptors:  cows, dairy cattle, dairy cows, dairy herds, Mycobacterium avium subsp. paratuberculosis, various strains, interferon, diagnosis, diagnostic techniques, ELISA, immunodiffusion, PCR, methodology, paratuberculosis, Argentina.

Patel, D.; Goddik, L.; Bermudez, L.  Invasion of Mycobacterium avium subsp paratuberculosis in bovine epithelial cells and bovine mammary epithelial cells.  Journal of Dairy Science.  2003; 86(Suppl. 1): 8.  ISSN:  0022-0302.  Note:  Joint Annual Meeting of the American Dairy Science Association, the American Society of Animal Science and the Mexican Association of Animal Production, Phoenix, Arizona, USA; June 22-26, 2003. 
URL:  http://jds.fass.org/contents-by-date.0.shtml
NAL Call No.:  44.8 J822
Descriptors:  Mycobacterium avium subsp. paratuberculosis, bovine epithelial cells, bovine mammary epithelial cells, cell invasion by bacterial pathogen. 

Payne, T.E.; Guillou, L. III; Awong Taylor, J.  A comparison of methods for detection of Mycobacterium paratuberculosis in bovine milk by IS900 PCR.  Abstracts of the General Meeting of the American Society for Microbiology.  2003; 103: U-026.  ISSN:  1060-2011.  Note:  103rd American Society for Microbiology General Meeting, Washington, DC, USA; May 18-22, 2003.
Descriptors:  bovine milk, method for detection, IS900PCR, Mycobacterium avium subsp. paratuberculosis, an isolation and concentration method utilizing Cetyltrimethylammonium Bromide (CTAB), pasteurized and unpasteurized milk.  

Pence, M.; Baldwin, C.; Black, C.C., III.  The seroprevalence of Johne's disease in Georgia beef and dairy cull cattle.  Journal of Veterinary Diagnostic Investigation.  2003; 15(5): 475-477.  ISSN:  1040-6387.
NAL Call No.:  SF774.J68
Descriptors:  beef cattle, dairy cattle, culled animals, sale barns sales, Johne’s disease, Mycobacterium avium subsp. paratuberculosis, epidemiology, 5307 sera of 200,000 were tested, ELISA test kit, levels of Johne’s disease culled animals was economically significant, Georgia, United States.

Pilipcinec, E.; Svicky, E.; Pistl, J.; Dorko, E.; Bugarsky, A.  Ochorenia lymfatickeho systemu vyvolane primarne bakteriami a plesnami. [Diseases of the lymph system caused primarily by the bacteria and moulds.]  Slovensky Veterinarsky Casopis.  2003; 28(3): 34-39.  ISSN:  1335-0099.  Note:  In Czech with an English summary.
Descriptors:  pigs, cats, horses, sheep, goats, other domestic animals, pathogens of the lymph system, zoonotic diseases, Corynebacterium pseudotuberculosis, Streptococcus equi subsp. equi, Rhodococcus equi, Streptococcus porcinus, Streptococcus canis, Histoplasma capsulatum subsp. farciminosum, Sporothrix schenckii, Streptococcus equi subsp. zooepidemicus, Yersinia pseudotuberculosis, Y. enterocolitica, Burkholderia mallei, B. pseudomallei, Mycobacterium avium subsp. paratuberculosis, Mycobacterium spp., Actinomyces spp., Nocardia spp., Aspergillus spp., Staphylococcus aureus, Actinobacillus equuli, Actinobacillus suis, Arcanobacterium pyogenes.   

Pislak, M.; Ocepek, M.; Piano, J.Z.; Pogacnik, M.  Comparison of four methods for isolation of Mycobacterium avium subsp. paratuberculosis DNA from tissue samples.  Slovenian Veterinary Research.  2003; 40(2): 91-97.  ISSN:  1581-6915.  Note:  In English with a summary in Slovenian.
Descriptors:  11 positive small ruminants, sheep, Mycobacterium avium subsp. paratuberculosis, 30 intestinal and lymph node samples, 4 methods of DNA extraction: (1) High Pure PCR Template Preparation Kit, Roche, Mannheim commercial kit; (2) treatment of samples with HPC (hexadecylpyridinium chloride) and isolation and kit; (3) Gwozdz’s method of digestion with proteinase K adding NaCl and cetyltrimethylammonium bromide (CTAB); (4) treatment with HPC and isolation with the method described by Gwozdz, method 2 was most efficient.

Pons, L. Sequencing the bad guys.  Agricultural Research.  2003; 51(4): 19.  ISSN: 0002-161X.
URL:  http://www.ars.usda.gov/is/AR/archive/apr03/bact0403.htm
NAL Call No.:  1.98 AG84
Descriptors:  cattle diseases, sequence analysis, nucleotide sequences, Mycobacterium avium subsp. paratuberculosis, Brucella melitensis biovar abortus, Leptospira interrogans serovar hardjo.

Radunz, B.  Johne's disease. Agdex no: 420/653.  Agnote Northern Territory of Australia.  2003; (K30): 2.  ISSN:  0157-8243.  
Descriptors:  buffalo, camelids, cattle, deer, goats, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, symptoms, spread, detection, incidence, disease transmission, mortality, epidemiology, Northern Territory, Australia.

Rajkhowa, S.; Rajkhowa, C.; Bujarbaruah, K.M.  Diseases of mithun (Bos frontalis) - a review.  Veterinary Bulletin.  2003; 73(4): 1R-6R.  ISSN:  0042-4854.
Descriptors:  mithun, Bos frontalis, animal diseases, foot and mouth disease, catarrhal fever, rinderpest, bacterial diseases, Mycobacterium avium subsp. paratuberculosis, bronchopneumonia by Pseudomonas spp., black quarter, Clostridium chauvoei, anthrax and brucellosis, nutritional edema, parasitoses, theileriasis, reviews.  

Reddacliff, L.A.; Whittington, R.J.  Culture of pooled tissues for the detection of Mycobacterium avium subsp. paratuberculosis infection in individual sheep.  Australian Veterinary Journal.  2003; 81(12): 766-767.  ISSN:  0005-0423
URL:  http://www.ava.com.au/avjpast.php?journalid=9&plink=avj03.htm
NAL Call No.:  41.8 AU72
Descriptors:  sheep, tissue homogenates, the terminal ileum (TI), ileocaecal valve (ICV), mesenteric lymph nodes (MLN), Mycobacterium avium subsp. paratuberculosis, samples pooled for each sheep, freezing and thawing, experimental infection, tissue culture, pooled as alternative to individual tissue analysis.

Reddacliff, L.A.; Vadali, A.; Whittington, R.J.  The effect of decontamination protocols on the numbers of sheep strain Mycobacterium avium subsp. paratuberculosis isolated from tissues and faeces.  Veterinary Microbiology.  2003; 95(4): 271-282.  ISSN:  0378-1135.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5190&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=7e99acb030d8f79b52d4e03a1c31a5f8
NAL Call No.:  SF601.V44
Descriptors:  Mycobacterium avium subsp. paratuberculosis, sheep strain, animal tissues, clinical samples, spiking tissues and feces, decontamination, culture techniques.

Reddacliff, L.A.; Whittington, R.J.  Experimental infection of weaner sheep with S strain Mycobacterium avium subsp. paratuberculosis.  Veterinary Microbiology.  2003; 96(3): 247-258.  ISSN:  0378-1135. 
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5190&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=7e99acb030d8f79b52d4e03a1c31a5f8
NAL Call No.:  SF601.V44
Descriptors:  recently weaned Merino lambs, sheep, experimental infection, Mycobacterium avium subsp. paratuberculosis, Australian S strain, oral doses similar to natural exposure, detection time, humoral immunity, interferon, pathogenesis, tissue culture, skin testing, skin testing, intradermal Johnin, whole blood IFN-gamma.

Reddacliff, Leslie A.; Nicholls, Paul J.; Vadali, Aparna; Whittington, Richard J.  Use of growth indices from radiometric culture for quantification of sheep strains of Mycobacterium avium subsp. paratuberculosis.  Applied and Environmental Microbiology.  2003; 69(6): 3510-3516.  ISSN:  0099-2240.
URL:  http://www.pubmedcentral.gov/tocrender.fcgi?action=archive&journal=83
NAL Call No.:  448.3 AP5
Abstract:  A simple method for using growth indices from radiometric BACTEC cultures was evaluated for the enumeration of Australian sheep strains of Mycobacterium avium subsp. paratuberculosis.  The numbers of viable organisms in inocula were determined by end-point titration in BACTEC cultures.  Growth indices were measured by using a BACTEC 460 machine.  There was a linear relationship between the number of days taken for the cumulative growth index to reach 1,000 (dCGI1000) and log10 inoculum size.  The use of dCGI1000 was shown to be as effective as the use of growth index data from the entire growth cycle for the estimation of inoculum size.  For particular isolates characterized by end-point titration, the dCGI1000 of a single BACTEC vial provided estimates of viable numbers within narrow prediction limits.  Predictive relationships were also established for the enumeration of M. avium subsp. paratuberculosis from field samples by using the dCGI1000 of a single BACTEC vial, with prediction limits of ˝1 to 2 log units.  Organisms from feces or contaminated soil grew more slowly than those from cultures or tissues, and separate equations were developed for enumeration from these sources.
Descriptors:  sheep, Mycobacterium avium subsp. paratuberculosis, bacterial strains, growth indices, cell culture, culture media, animal pathogenic bacteria, microbial growth, laboratory techniques, enumeration strains, paratuberculosis, sheep diseases, radiometric BACTEC culture, diagnosis, diagnostic techniques.  

Reid, S.W.J.; Menzies, F.D.  Global context, generic tools: epidemiology for disease control on an international stage.  Preventive Veterinary Medicine.  2003; 60(1): 132.  ISSN:  0167-5877.  Note:  An issue of 8 papers by a variety of authors on a variety of topics.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5145&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=c5bc3d9e1bb66468352ae1f5475d522f
NAL Call No.:  SF601.P7
Descriptors: infectious disease epidemiology, animal health, a variety of bacterial and viral diseases, risk analysis, disease control and prevention, the Dutch Johne’s disease control program.

Rodriguez Lazaro, D.; Lloyd, J.; Pla, M.; Ikonomopoulos, I.; Cook, N.  Nucleic acid sequence-based amplification (NASBA) detects DNA in Mycobacterium avium subsp. paratuberculosis.  FEMS Congress of European Microbiologists Abstract Book.  2003; (1): 289.  Note:  1st Federation of European Microbiological Societies (FEMS) Congress of European Microbiologists, Ljubljana, Slovenia; June 29-July 03, 2003.
Descriptors:  Mycobacterium avium subsp. paratuberculosis, DNA analysis, sequence based amplification of nucleic acids, enzyme uses.

Rosa, G.J.M.; Tempelman, R.J.; Suchyta, S.; Madsen, S.A.; Burton, J.L.; Coussens, P.M.  Normalization, replication, and significance tests in cDNA microarray experiments.  Journal of Dairy Science.  2003; 86(Suppl. 1): 159.  ISSN:  0022-0302.  Note:  Joint Annual Meeting of the American Dairy Science Association, the American Society of Animal Science and the Mexican Association of Animal Production, Phoenix, Arizona, USA; June 22-26, 2003.
URL:  http://jds.fass.org/contents-by-date.0.shtml
NAL Call No.:  44.8 J822
Descriptors: cattle disease, Johne’s disease, Mycobacterium avium subsp. paratuberculosis, cDNA, molecular genetics.

Rossiter-Burhans, C.A.; Barlow, J.W.; Johnson, T.E.  Vermont Cattle Health Improvement Project.  Journal of Dairy Science.  2003; 86(Suppl. 1): 134.  ISSN:  0022-0302.  Note:  Joint Annual Meeting of the American Dairy Science Association, the American Society of Animal Science and the Mexican Association of Animal Production, Phoenix, Arizona, USA; June 22-26, 2003. 
URL:  http://jds.fass.org/contents-by-date.0.shtml
NAL Call No.:  44.8 J822
Descriptors:  Johne’s disease, disease control program, disease prevention, Vermont, United States.  

Saunders, V.F.; Eamens, G.J.; Turner, M.J.; Jessep, T.M.  Identification of a new RFLP type of Mycobacterium avium subsp. paratuberculosis in epidemiological tracing of bovine Johne's disease.  Australian Veterinary Journal.  2003; 81(9): 564-566.  ISSN:  0005-0423.
URL:  http://www.ava.com.au/avjpast.php?journalid=9&plink=avj03.htm
NAL Call No.:  41.8 AU72
Descriptors:  cattle, disease prevalence, disease transmission, epidemiology, genes, RFLP, Johne’s disease, Australia.

Seuna, E.; Seppanen, J.  National control strategies and ongoing research in Finland.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 251-253.  ISSN:  0044-605X.
NAL Call No.:  41.8 AC87
Descriptors:  cattle, Mycobacterium avium subsp. paratuberculosis, diagnosis, disease surveys, paratuberculosis, national Johne’s disease control program, Finland.

Sergeant, E.S.G.  Estimated flock-prevalence and distribution of ovine Johne's disease in Australia at December 2001.  Australian Veterinary Journal.  2003; 81(12): 768-769.  ISSN:  0005-0423.
URL:  http://www.ava.com.au/avjpast.php?journalid=9&plink=avj03.htm
NAL Call No.:  41.8 AU72
Descriptors:  sheep, Mycobacterium avium subsp. paratuberculosis, disease prevalence, distribution, New South Wales, Australia.

Sergeant, E.S.G.; Marshall, D.J.; Eamens, G.J.; Kearns, C.; Whittington, R.J.  Evaluation of an absorbed ELISA and an agar-gel immuno-diffusion test for ovine paratuberculosis in sheep in Australia.  Preventive Veterinary Medicine.  2003; 61(4): 235-248.  ISSN:  0167-5877.  
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5145&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=c5bc3d9e1bb66468352ae1f5475d522f
NAL Call No.:  SF601.P7
Descriptors:  sheep, Mycobacterium avium subsp. paratuberculosis, body condition, Johne’s disease detection, known infected and non-infected flocks, diagnosis, diagnostic techniques, sensitivities and specificities, absorbed ELISA, agar gel immunodiffusion tests, histological lesion score, paratuberculosis, logistic-regression analysis on lesion and condition scores, New South Wales, Australia.

Sheridan, Joe M.; Bull, Tim J.; Hermon-Taylor, John.  Use of bioinformatics to predict a function for the GS element in Mycobacterium avium subspecies paratuberculosis.  Journal of Molecular Microbiology and Biotechnology.  2003; 5(1): 57-66.  ISSN:  1464-1801.  
URL:   http://www.jmmb.net/
NAL Call No.:  QR74.J68
Descriptors:  Mycobacterium avium subsp. paratuberculosis, homology of GS genes, ser2 region, Mycobacterium avium subsp. avium, bioinformatics, Johne’s disease, cell wall GPL, possible drug target, Crohn's disease, paratuberculosis.

Shin, S.J.; Chang, Y.F.; Yoo, H.S.  Immunological comparison of major proteins in Mycobacterium avium spp. paratuberculosis.  FEMS Congress of European Microbiologists Abstract Book.  2003; (1): 55-56.  Note:  1st Federation of European Microbiological Societies (FEMS) Congress of European Microbiologists, Ljubljana, Slovenia; June 29-July 03, 2003.
Descriptors:  Mycobacterium avium subsp. paratuberculosis, proteins, immunology, comparative immune response.

Shulaw, W.P.; Larew-Naugle, A.  Paratuberculosis: a food safety concern?  In:  Torrence, M.E.; Isaacson, R.E.  Microbial Food Safety in Animal Agriculture: Current Topics.  Iowa State Press,  Ames, Iowa.  2003; 351-358.  ISBN:  0813814952.
NAL Call No.:  QR115.M4564  2003
Descriptors:  Mycobacterium avium subsp. paratuberculosis, etiology, zoonotic concerns, food borne disease, Crohn’s disease, food contamination, food safety.

Singh, D.K.  Prevention and control of infectious diseases of buffaloes.  Intas Polivet.  2003; 4(2): 292-298.  ISSN:  0972-1738.  
Descriptors:  buffalo, infectious diseases, animal pathogens, bacteria, viruses, parasites, disease prevention and control, anthrax, Brucella, foot and mouth disease; hemorrhagic septicemias, rabies, rhinotracheitis, rinderpest, trypanosoma, tuberculosis, paratuberculosis, bovine diarrhea virus, bovine ephemeral fever virus, buffalo poxvirus, Campylobacter fetus, Clostridium chauvoei, Mycobacterium avium subsp. paratuberculosis, Mycobacterium tuberculosis, Pasteurella multocida, rabies virus, rinderpest virus.

Singh, S.V.; Vihan, V.S.  Incidence of Mycobacterium avium sub sp. paratuberculosis in clinicaly suspected small ruminants.  Indian Journal of Small Ruminants.  2003; 9(1): 56-59.  ISSN:  0971-9857.
Descriptors:  goats, sheep, incidence of disease, Mycobacterium avium subsp. paratuberculosis, microscopic examination, 1038 clinically suspected animals, India.

Sivakumar, P., Tripathi, B.N., Nem Singh.  Comparison of different methods of DNA extraction from Mycobacterium avium subsp. paratuberculosis infected tissues of buffaloes.  Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases.  2003; 24(1): 43-47.  ISSN:  0970-9320.  
Descriptors:  buffalo, infected with Mycobacterium avium subsp. paratuberculosis, different methods of DNA extraction of bacterial pellets, mucosal homogenate of infected intestines, extraction methods, freezing thawing and freezing boiling, centrifugation, diagnosis, diagnostic techniques, PCR DNA amplification.

Smith, W.L.; McGarvey, K.L.; Cullor, J.S.  The use of spiral plating and microscopic colony counting for the rapid quantitation of Mycobacterium paratuberculosis.  Letters in Applied Microbiology.  2003; 36(5): 293-296.  ISSN:  0266-8254.  
URL:  http://www.blackwell-synergy.com/links/doi/10.1046/j.1472-765X.2003.01311.x/abs/
NAL Call No.:  QR1.L47
Descriptors:  Mycobacterium avium subsp. paratuberculosis, quantitation by spiral plating and microscopic colony counting, broth and milk cultures, varying incubation periods, Middlebrook agar plates counted 8-14 days and 27-28 days.

Sorensen, O.; Rawluk, S.; Wu, J.; Manninen, K.; Ollis, G.  Mycobacterium paratuberculosis in dairy herds in Alberta.  Canadian Veterinary Journal.  2003; 44(3): 221-226.  ISSN:  0008-5286.  Note:  In English with a French summary.  
URL:    http://www.pubmedcentral.nih.gov/tocrender.fcgi?action=archive&journal=202
NAL Call No.:  41.8 R3224
Descriptors:  50 dairy herds, herd level prevalence, Mycobacterium avium subsp. paratuberculosis, pooled fecal culture, ELISA of serum, Alberta, Canada.

Sreedevi, B.; Krishnappa, G.  Detection of Mycobacterium tuberculosis complex organisms in clinical samples of cattle by PCR and DNA probe methods.  Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases.  2003; 24(2): 167-171.  ISSN:  0970-9320.
Descriptors:  cattle, diagnosis, diagnostic techniques, DNA probes, polymerase chain reaction, tuberculin, tuberculosis, IS6110 element, Mycobacterium tubuculosis complex, differential subspecies separation, Mycobacterium avium, Mycobacterium avium subsp. paratuberculosis, Mycobacterium bovis, Mycobacterium bovis BCG strain, Mycobacterium phlei, Mycobacterium tuberculosis, Karnataka, India.  

Srivastava, Bejai Inder Sahai; Srivastava, Maya Devi.  A novel, more rapid method for the detection and discrimination of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. paratuberculosis. FASEB Journal.  2003; 17(4-5): Abstract no. 408.5.  ISSN:  0892-6638.  Note:  FASEB Meeting on Experimental Biology: Translating the Genome, San Diego, CA, USA; April 11-15, 2003.
URL:  http://www.fasebj.org/
NAL Call No.:  QH301.F3
Descriptors:  detection and discrimination between Mycobacterium avium subsp. avium and Mycobacterium avium subsp. paratuberculosis, methods, CaCo2 cell line, SRIK-NKL cell line, bacterial growth differences.

Stabel, J.R.; Goff, J.P.; Kimura, K.  Effects of supplemental energy on metabolic and immune measurements in periparturient dairy cows with Johne's diseases.  Journal of Dairy Science. 2003; 86(11): 3527-3535.  ISSN: 0022-0302.
URL:  http://jds.fass.org/contents-by-date.0.shtml
NAL Call No.:  44.8 J822
Abstract:  The present study was designed to evaluate whether feeding supplemental energy would improve the metabolic profile and alleviate some of the immunosuppression typically noted during the periparturient period in dairy cows with Johne's disease.  Twelve dairy cows naturally infected with Mycobacterium paratuberculosis were fitted with rumen cannulas in late gestation and assigned to treatment groups: control, n = 6; or stuffed, n = 6.  Cows in the control group were allowed to consume feed ad libitum.  Cows assigned to the stuffed treatment group were also fed ad libitum but received additional total mixed rations by manually stuffing their rumens with refused feed to maintain dry matter intake of 2% body weight per day before calving and 2.5% body weight per day after calving.  Serum nonesterified fatty acid levels were significantly decreased in stuffed cows compared with control cows, indicating that stuffing to maintain dry matter intake improved the energy balance in the cows.  In addition, periparturient serum calcium and magnesium concentrations were significantly higher in stuffed cows.  Stuffing modulated cell-mediated immunity by reducing lymphocyte proliferative responses to T-cell mitogens during early lactation.  Stuffing resulted in an increase in the secretion of in vitro immunoglobulin by peripheral blood mononuclear cells after parturition when compared to control cows.  These data demonstrate that energy balance is improved by providing additional energy in this manner and suggest energy supplementation can improve some aspects of immune function during the periparturient period.
Descriptors:  dairy cows, perinatal period, cow feeding, rumen cannulas, voluntary intake, overfeeding, energy balance, paratuberculosis, cattle bacterial diseases, Mycobacterium avium subsp. paratuberculosis, blood serum, calcium, magnesium, phosphorus, lymphocyte proliferation, blood lipids, free fatty acids, blood glucose, calcitriol, cell mediated immunity, humoral immunity.

Stabel, J.R.; Palmer, M.V.; Whitlock, R.H.  Immune responses after oral inoculation of weanling bison or beef calves with a bison or cattle isolate of Mycobacterium avium subsp. paratuberculosis.  Journal of Wildlife Diseases.  2003; 39(3): 545-555.  ISSN:  0090-3558.
URL:  http://www.jwildlifedis.org/
NAL Call No.:  41.9 W64B
Descriptors:  young animals, domestic and wild ruminants, cattle, bison calves, beef calves, host immune responses, pathologic changes, pathogenesis, physiopathology, experimental infection with Mycobacterium avium subsp. paratuberculosis that are both cattle or bison strains, oral dosing, cattle isolate, bison strain, blood sampling, fecal sampling, tissues samples at necropsy, disease resistance, demonstrated species differences to pathogen challenge, lesions, jejunum, distal ileum, IFN gamma, species response differences.

Sternberg, S.; Viske, D.  Control strategies for paratuberculosis in Sweden.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 247-249.  ISSN:  0044-605X.
NAL Call No.:  41.8 AC87
Descriptors:  cattle, control program for Johne’s, Mycobacterium avium subsp. paratuberculosis, diagnosis, diagnostic techniques, Sweden.

Storset, A.K.  Immunology of Mycobacterium avium subsp. paratuberculosis infection - immunodiagnostic methods.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 223-229.  ISSN:  0044-605X.  
NAL Call No.:  41.8 AC87
Descriptors:  Johne’s disease, Mycobacterium avium subsp. paratuberculosis, immune response, immunity, interferon, immunodiagnosis, immunodiffusion tests, immunology, diagnostic techniques, ELISA, skin tests.

Stott, A.W.; Jones, G.J.; Humphry, R.W.; Gunn, G.J.  An economic evaluation of Johne's disease (paratuberculosis) in the dairy herd using dynamic programming.  Acta Veterinaria Scandinavica Supplementum.  2003; (supp. 98): 262.  ISSN:  0065-1699.  Note:  J.F. Agger and N. Toft edited the special issue.
NAL Call No.:  41.8 AC87 suppl
Descriptors:  dairy cattle, dairy herds, economic impact of Johne’s disease, Mycobacterium avium subsp. paratuberculosis, culling sick animals, milk prices, dynamic programming, Great Britain.  

Sung, N.; Collins, M.T.  Variation in resistance of Mycobacterium paratuberculosis to acid environments as a function of culture medium.  Applied and Environmental Microbiology.  2003; 69(11): 6833-6840.  ISSN:  0099-2240.
URL:  http://www.pubmedcentral.gov/tocrender.fcgi?action=archive&journal=83
NAL Call No.:  448.3 AP5
Descriptors:  Mycobacterium avium subsp. paratuberculosis, in vitro culture conditions, acid resistance, fatty acid medium, glycerol containing medium, both at pH 6.0, 6.8., reistant to acetate buffer at pH 3,4,5 6 at 20 degrees C, BACTE used to identify viable cells, measured soluable proteins, death, growth rate, morphology, comparison study, culture conditions are very important.

Tharaldsen, J.; Djonne, B.; Fredriksen, B.; Nyberg, O.; Sigurdardottir, O.  The national paratuberculosis program in Norway.  Acta Veterinaria Scandinavica.  2003; 44(3/4): 243-246.  ISSN:  0044-605X.  
NAL Call No.:  41.8 AC87
Descriptors:  cattle, goats, llamas, Johne’s disease, Mycobacterium avium subsp. paratuberculosis, disease seroprevalence, disease surveys, epidemiology, immunodiagnosis, national control program, Norway.

Tiwari, A.; VanLeeuwen, J.A.; Dohoo, I.R.; Stryhn, H.; Keefe, G.P.  Effect of seropositivity for bovine leukaemia virus, Mycobacterium avium subspecies paratuberculosis, and Neospora caninum on the calving to conception interval in maritime Canadian dairy cattle.  Proceedings of a Meeting - Society for Veterinary Epidemiology and Preventive Medicine. [Great Britain]2003; 243-252.  ISSN: 0956-7496.  Note:  Meeting held March 31-April 2, 2003, Warwick, England.
NAL Call No.:  SF780.9.S63
Descriptors:  dairy cattle, bovine leukemia virus, Mycobacterium avium subsp. paratuberculosis, Neospora caninum, seroprevalence, reproductive efficiency, Canada.

Toman, M.; Faldyna, M.; Pavlik, I.  Immunological characteristics of cattle with Mycobacterium avium subsp. paratuberculosis infection.  Veterinarni Medicina.  2003; 48(6): 147-154.  ISSN:  0375-8427.
URL:  http://vetmed.vri.cz/
NAL Call No.:  41.9 C333
Descriptors:  cattle infected with Johne’s disease, disease progression, clinical aspects, Mycobacterium avium subsp. paratuberculosis, antibodies, leukocytes, lymphocytes, monocytes, neutrophils, CD4+ lymphocytes, CD8+ lymphocytes, cell mediated immunity, interferon.

Tortoli, Enrico.  Impact of genotypic studies on mycobacterial taxonomy: The new mycobacteria of the 1990s.  Clinical Microbiology Reviews.  2003; 16(2): 319-354.  ISSN:  0893-8512.  
URL:  http://www.pubmedcentral.gov/articlerender.fcgi?artid=153142
NAL Call No.:  QR67.C54
Descriptors:  Mycobacterium avium subsp. paratuberculosis, Mycobacterium avium subsp. avium, Mycobacterium avium subsp. caprae, Mycobacterium avium subsp. hominissuis, Mycobacterium avium subsp. silvaticum, non-pigmented, pigmented, rapid growers, slow growers, taxonomy.

Uhart, Marcela M.; Vila, Alejandro R.; Beade, Mario S.; Balcarce, Alfredo; Karesh, William B.  Health evaluation of pampas deer (Ozotoceros bezoarticus celer) at Campos del Tuyu Wildlife Reserve, Argentina.  Journal of Wildlife Diseases.  2003; 39(4): 887-893.  ISSN:  0090-3558.
URL:  http://www.jwildlifedis.org/
NAL Call No.:  41.9 W64B
Descriptors:  pampas deer, free ranging, hematology, serum chemistries, minerals, metals, fecal parasites, seasonal evaluation of fecal ova and parasites, animal diseases, bluetongue, brucellosis, bovine respiratory syncytial virus infection, bovine viral diarrhea/mucosal disease, infectious bovine rhinotracheitis, Johne's disease (paratuberculosis), foot and mouth disease (FMD), leptospirosis (eight serovars), epizootic hemorrhagic disease, and parainfluenza-3 (PI-3), negative for paratuberculosis, Campos del Tuyu Wildlife Reserve, Buenos Aires, Argentina.

Underwood, S.C.; Decaminada, E.C.; Grimoldi, F.; Moras, E.V.; Carfagnini, J.C.  Estudio de la prevalencia de brucelosis, tuberculosis y paratuberculosis en cabras lecheras y carniceras pertenecientes a minifundistas de Santiago del Estero.  [Prevalence of brucellosis, tuberculosis and Johne's disease in smallholders' dairy and meat goats from Santiago del Estero].  Revista Argentina de Produccion Animal.  2003; 23(1): 53-61.  ISSN:  0326-0550.  Note:  In Spanish with an English summary.
Descriptors:  dairy and meat goats, 31 farms with10 animals/farm, prevalence of brucellosis, Brucella melitensis, BPA test, tuberculosis, Mycobacterium bovis, Johne’s disease, cervical comparative test for Mycobacterium avium subsp. paratuberculosis, percentages of disease incidence, Argentina.

Uzonna, J.E.; Chilton, P.; Whitlock, R.H.; Habecker, P.L.; Scott, P.; Sweeney, R.W.  Efficacy of commercial and field-strain Mycobacterium paratuberculosis vaccinations with recombinant IL-12 in a bovine experimental infection model.  Vaccine.  2003; 21(23): 3101-3109.  ISSN:  0264-410X.  
NAL Call No.:  QR189.V32
Descriptors:  calves, vaccine testing model, Mycobacterium avium subsp. paratuberculosis, commercial Strain 18 and field isolate, vaccine response, strong local systemic and enteric IFN-gamma responses, field isolate showed reduced bacterial colony formation, field isolate vaccine recommended over Strain 18.

Van Schaik, G.; Rossiter, C.R.; Stehman, S.M.; Shin, S.J.; Schukken, Y.H.  Longitudinal study to investigate variation in results of repeated ELISA and culture of fecal samples for Mycobacterium avium subsp paratuberculosis in commercial dairy herds.  American Journal of Veterinary Research.  2003; 64(4): 479-484.  ISSN: 0002-9645.
URL:  http://avmajournals.avma.org/toc/ajvr/64/4
NAL Call No.:  41.8 AM3A
Descriptors:  Mycobacterium avium subsp. paratuberculosis, dairy herd, Johne’s disease, fecal samples, fecal cultures, ELISA, consistency of results, diagnostic method comparison, repeated tests of 112 cows on 6 commercial dairy farms, New York, United States.

Van Schaik, G.; Stehman, S.M.; Schukken, Y.H.; Rossiter, C.R.; Shin, S.J.  Pooled fecal culture sampling for Mycobacterium avium subsp. paratuberculosis at different herd sizes and prevalence.  Journal of Veterinary Diagnostic Investigation.  2003; 15(3): 233-241.  ISSN:  1040-6387.
NAL Call No.:  SF774.J68
Descriptors:  dairy cows, dairy herds, whole herd testing, Johne’s disease, stochastic spreadsheet model, disease prevalence of Mycobacterium avium subsp. paratuberculosis, detection, diagnosis, disease distribution, epidemiology, pooled fecal sampling, fecal testing of individuals from farms with pooled positives, paratuberculosis, allocation of disease status as 1) not shedding, 2) low shedder, 3) moderate shedder, 4) heavy shedder, efficiency depends on ratio of positives to herd size of pooled samples, New York State, United States.  

Van Schaik, G.; Schukken, Y.H.; Crainiceanu, C.; Muskens, J.; Van Leeuwen, J.A.  Prevalence estimates for paratuberculosis adjusted for test variability using Bayesian analysis.  Preventive Veterinary Medicine.  2003; 60(4): 281-295.  ISSN:  0167-5877.
URL:  http://www.sciencedirect.com/science?_ob=JournalURL&_cdi=5145&_auth=y&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=c5bc3d9e1bb66468352ae1f5475d522f
NAL Call No.:  SF601.P7
Descriptors:  cattle herd testing, Mycobacterium avium subsp. paratuberculosis, ELISA testing, diagnostic techniques, disease prevalence, mathematical models, Bayesian theory, testing sensitivity and specificity, estimating true disease prevalence of Johne’s disease, epidemiology.

Veerabramhaiah, K.; Kumar, K.S.; Rao, S.T.V.; Naidu, P.T.  Clinico-pathological aspects of an unusual paratuberculosis in a crossbred cow.  Intas Polivet.  2003; 4(1): 32-33.  ISSN:  0972-1738. 
Descriptors:  crossbred cow, Mycobacterium avium subsp. paratuberculosis, Johne’s disease, unusual case, clinical aspects, mortality, post mortem examination, animal pathology, case reports, Andhra Pradesh, India.

Wapenaar, W.; Van Schaik, G.; Leids, P.; Denney, L.; Schukken, Y.H.; Stehman, S.M.; Huntley, J.  NYSCHAP Johne's disease module, a program to change management of dairy farms to reduce Johne's disease prevalence.  Bovine Practitioner.  2003; 37(1): 23-29.  ISSN:  0524-1685.  Note:  In English with a French summary.
NAL Call No.:  SF779.5.A1B6
Descriptors:  dairy cows, dairy farms, New York State Cattle Health Assurance Program, Johne’s disease control, epidemiology, Johne’s Disease Module, success of training, adoption of management practices, milk production, disease prevalence, epidemiology, reviews, New York State, United States.

Wapenaar, W.; Leids, P.; Denney, L.; Van Schaik, G.; Stehman, S.; Schukken, Y.H.; Huntley, J.  A program to change management of dairy farms to reduce Johne's disease prevalence.  Acta Veterinaria Scandinavica, Supplementum.  2003; (Suppl. 98): 240.  ISSN:  0065-1699.  Note:  J.F. Agger and N. Toft edited the special issue.
NAL Call No.:  41.8 AC87 Suppl.
Descriptors:  dairy cattle, dairy farms, Mycobacterium avium subsp. paratuberculosis, disease control programs, disease prevalence, epidemiology farm management, biosecurity, New York, United States.

Waters, W.R.; Miller, J.M.; Palmer, M.V.; Stabel, J.R.; Jones, D.E.; Koistinen, K.A.; Steadham, E.M.; Hamilton, M.J.; Davis, W.C.; Bannantine, J.P.  Early induction of humoral and cellular immune responses during experimental Mycobacterium avium subsp. paratuberculosis infection of calves.  Infection and Immunity.  2003; 71(9): 5130-5138.  ISSN:  0019-9567.
URL:  http://www.jarvm.com/
NAL Call No.:  QR1.I57
Descriptors:  cattle, young animals, calves, experimental infections, Mycobacterium avium subsp. paratuberculosis, early immune response, antibodies CD4+ lymphocytes, interferon, nitric oxide, paratuberculosis, Johne’s disease.

Wells, S.J.; Godden, S.M.; Lindeman, C.J.; Collins, J.E.  Evaluation of bacteriologic culture of individual and pooled fecal samples for detection of Mycobacterium paratuberculosis in dairy cattle herds.  Journal of the American Veterinary Medical Association.  2003; 223(7): 1022-1025.  ISSN:  0003-1488.
URL:  http://avmajournals.avma.org/toc/javma/223/7
NAL Call No.:  41.8 AM3
Descriptors:  24 dairy cattle herds, detecting Mycobacterium avium subsp. paratuberculosis, individual and pooled fecal samples, in vitro culture methods, using pooled sampling and testing is cost effective, disease prevalence, Minnesota, United States.

Whittington, R.  The Future of OJD Control in Australia. 2003; 7 p.
Descriptors:  sheep, ovine Johne's disease (OJD), National OJD Control and Evaluation Programme (NOJDP), aims, delivery, policies to control spread, surveys, program structure, Australia.

Whittington, R.J.; Marsh, I.B.; Taylor, P.J.; Marshall, D.J.; Taragel, C.; Reddacliff, L.A.  Isolation of Mycobacterium avium subsp. paratuberculosis from environmental samples collected from farms before and after destocking sheep with paratuberculosis.  Australian Veterinary Journal.  2003; 81(9): 559-563.  ISSN:  0005-0423.  
URL:  http://www.ava.com.au/avjpast.php?journalid=9&plink=avj03.htm
NAL Call No.:  41.8 AU72
Descriptors:  sheep, goats, disease prevalence, Mycobacterium avium subsp. paratuberculosis, isolation from the environment, soil, feces, water, sediment, microbial contamination of the environment, effect of removing pathogen carrying animals, paratuberculosis, radiometric culture in environmental samples, reduction of pathogens after animal removal.

Whittington, R.J.; Eamens, G.J.; Cousins, D.V.  Specificity of absorbed ELISA and agar gel immunodiffusion tests for paratuberculosis in goats with observations about use of these tests in infected goats.  Australian Veterinary Journal.  2003; 81(1-2): 71-75.  ISSN:  0005-0423.
URL:  http://www.ava.com.au/avjpast.php?journalid=9&plink=avj03.htm
NAL Call No.:  41.8 AU72
Descriptors:  goats, Mycobacterium avium subsp. paratuberculosis, various isolates of bovine, or caprine origin, specificity of serological tests, laboratory experiments, 4 diagnostic test studied, AGID, ELISA< CSL PARACHEK, Johne’s absorbed ELISA, comparison study, antigen testing, diagnostic value, immunodiagnosis, immunodiffusion tests, paratuberculosis, quality controls.

Yousof-Beygi, G.; Ramin, A.G.; Faraji-Vand, A.R.  Study on the prevalence of subclinical cattle Johne's disease in the Urmia abattoir.  Archives of Razi Institute.  2003; (55): 63-69.  ISSN:  0365-3439.
Descriptors:  cattle, Mycobacterium avium subsp. paratuberculosis, prevalence of subclinical Johne’s, post slaughter tissue collection, 97 male and 196 female cattle, fecal sampling, epithelial tissue from between ileum and caecum, seasonal differences, no differences between different ages and sexes, Iran.

Zhu, Wenming; Plikaytis, Bonnie B.; Shinnick, Thomas M.  Resuscitation factors from mycobacteria: Homologs of Micrococcus luteus proteins.  Tuberculosis.  2003; 83(4): 261-269.  ISSN:  1472-9792.  
URL:  http://www.sciencedirect.com/science?_ob=IssueURL&_tockey=%23TOC%237161%232003%23999169995%23442814%23FLA%23&_auth=y&view=c&_acct=C000052423&_version=1&_urlVersion=0&_userid=4250348&md5=a50f3e526fd7006af102643d661aaa81
Descriptors:  cloning and characterizing resuscitation promoting factors, Mycobacterium avium subsp. paratuberculosis, Mycobacterium tuberculosis, recovery from late stationary culture.


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