ISSN: 1052-5378qb9421

AWIC

Anesthesia and Analgesia for Farm Animals

Provided by the Animal Welfare Information Center

United States Department of Agriculture
National Agricultural Library

January 1987 - January 1994

United States Department of Agriculture
National Agricultural Library
10301 Baltimore Blvd.
Beltsville, Maryland 20705-2351

QB 94-21

Updated by QB 95-13



Quick Bibliography Series Bibliographies in the Quick Bibliography Series of the National Agricultural Library, are intended primarily for current awareness, and as the title of the series implies, are not indepth exhaustive bibliographies on any given subject. However, the citations are a substantial resource for recent investigations on a given topic. They also serve the purpose of bringing the literature of agriculture to the interested user who, in many cases, could not access it by any other means. The bibliographies are derived from computerized on-line searches of the AGRICOLA data base. Timeliness of topic and evidence of extensive interest are the selection criteria.

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Read Bullet 16 on ALF for information on Document Delivery services. Read Bullet 15 for "Electronic Mail Access For Interlibrary Loan (ILL) Requests." If the text of this Quick Bibliography file is copied and/or distributed, please include in all copies, the information provided in these bulletins. Anesthesia and Analgesia for Farm Animals January 1987 - January 1994

Quick Bibliography Series: QB 94-21

336 citations in English from AGRICOLA

Tim Allen
Animal Welfare Information Center

April 1994 National Agricultural Library Cataloging Record:

Allen, Tim
Anesthesia and analgesia for farm animals.
(Quick bibliography series ; 94-21)
1. Animal anesthesia--Bibliography. 2. Domestic animals--Bibliography. I. Title.
aZ5071.N3 no.94-21

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AGRICOLA

Citations in this bibliography were entered in the AGRICOLA database between January 1979 and the present.

SAMPLE CITATIONS
 
 Citations in this bibliography are from the National Agricultural Library's
 AGRICOLA database.  An explanation of sample journal article, book, and
 audiovisual citations appears below.
 
 JOURNAL ARTICLE:
 
   Citation #                                     NAL Call No.
   Article title.
   Author.  Place of publication:  Publisher.  Journal Title.
   Date.  Volume (Issue).  Pages.  (NAL Call Number).
 
 Example:
   1                             NAL Call No.:  DNAL 389.8.SCH6
   Morrison, S.B.  Denver, Colo.:  American School Food Service
   Association.  School foodservice journal.  Sept 1987. v. 41
   (8). p.48-50. ill.
 
 BOOK:
 
   Citation #                                   NAL Call Number
   Title.
   Author.  Place of publication:  Publisher, date. Information
   on pagination, indices, or bibliographies.
 
 Example:
   1                        NAL Call No.:  DNAL RM218.K36 1987
   Exploring careers in dietetics and nutrition.
   Kane, June Kozak.  New York:  Rosen Pub. Group, 1987.
   Includes index.  xii, 133 p.: ill.; 22 cm.  Bibliography:
   p. 126.
 
 AUDIOVISUAL:
 
   Citation #                                  NAL Call Number
   Title.
   Author.  Place of publication:  Publisher, date.
   Supplemental information such as funding.  Media format
   (i.e., videocassette):  Description (sound, color, size).
 
 Example:
   1                    NAL Call No.: DNAL FNCTX364.A425 F&N AV
   All aboard the nutri-train.
   Mayo, Cynthia.  Richmond, Va.:  Richmond Public Schools,
   1981.  NET funded.  Activity packet prepared by Cynthia
   Mayo.  1 videocassette (30 min.): sd., col.; 3/4 in. +
   activity packet.Anesthesia and Analgesia for Farm Animals
                            January 1987 - January 1994
 
 
 
                             SEARCH STRATEGY
 
 Set     Items   Description
 
 1       4263    anesthe? or anasthe? or anaesthe? or analges? or pain? or
                 distress? or tranquil? or anxiolytic
 
 2       197462  cow or cows or cattle or sheep or pigs or swine or boar? or
                 pig? or barrow? or horse? or mare? or stallion? or livestock?
                 or bull? or lamb? or ram? or ewe?
 
 3       55438   pony or ponies or foal or colt? or chicken? or chick or chicks
                 or poult? or hen? or rooster? or turkey? or duck? or geese or
                 goose or llama? or emu? or ostrich?
 
 4       34124   rhea? or goat? or equine? or bovine? or ovine? or buffalo?
 
 5       262907  S2 or S3 or S4
 
 6       1036    S1 and S5/title
 
 7       446     S6 and LA=English and PY=1987:1994
 
 
 
 
Anesthesia and Analgesia for Farm Animals
1 NAL Call. No.: SF601.A47 Acetaminophen toxicosis: a potential model for acute liver failure in swine. Artwohl, J.E.; Henne-Bruns, D.; Carter, E.; Cera, L.M. Manhattan, Kan. : American Academy of Veterinary and Comparative Toxicology; 1988 Aug. Veterinary and human toxicology v. 30 (4): p. 324-328. ill; 1988 Aug. Includes references. Language: English Descriptors: Pigs; Analgesics; Poisoning; Liver function; Biopsy 2 NAL Call. No.: SF601.A46 Acupuncture for the treatment of chronic back pain in 200 horses. Martin, B.B. Jr; Klide, A.M. Lexington, Ky. : The Association; 1992. Proceedings of the annual convention of the American Association of Equine Practitioners (37): p. 593-601; 1992. Meeting held December 1-4, 1991, San Francisco, California. Includes references. Language: English Descriptors: Horses; Acupuncture; Pain 3 NAL Call. No.: SF910.P34A55 1992 Acute pain from castration and tail docking of lambs. Molony, V.; Wood, G.N. New York : Churchill Livingstone; 1992. Animal pain / edited by Charles E. Short, Alan Van Poznak. p. 385-395, 400-401; 1992. Includes references. Language: English Descriptors: Lambs; Pain; Tail; Cutting; Castration; Anesthesia; Local anesthesia; Xylazine; Morphine; Etorphine; Naloxone; Drug effects 4 NAL Call. No.: 41.8 R3224 Alleviation of postanesthetic hypoxemia in the horse. McMurphy, R.M.; Cribb, P.H. Ottawa : Canadian Veterinary Medical Association; 1989 Jan. The Canadian veterinary journal v. 30 (1): p. 37-41; 1989 Jan. Includes references. Language: English Descriptors: Horses; Anesthesia; Adverse effects; Hypoxia; Therapy; Oxygen; Partial pressure 5 NAL Call. No.: 442.8 J8222 Alterations in pituitary gland sensitivity in ram lambs to physiological doses of gonadotrophin-releasing hormone (GnRH), after divergent selection based on the luteinizing hormone response to a pharmacological GnRH challenge. Evans, N.P.; McNeilly, J.R.; Springbett, A.J.; Webb, R. Colchester : The Journal; 1991 Nov. Journal of reproduction and fertility v. 93 (2): p. 559-567; 1991 Nov. Includes references. Language: English Descriptors: Rams; Lambs; Lines; Gnrh; Lh; Hormone secretion; Anesthesia; Injectable anesthetics; Dosage effects; Line differences; Hypothalamus; Pituitary 6 NAL Call. No.: 41.8 R312 Analgesic activity and respiratory effects of butorphanol in sheep. Waterman, A.E.; Livingston, A.; Amin, A. London : British Veterinary Association; 1991 Jul. Research in veterinary science v. 51 (1): p. 19-23; 1991 Jul. Includes references. Language: English Descriptors: Sheep; Analgesics; Dosage; Pain; Respiratory gases; Mechanical stimulation; Heat tolerance Abstract: The analgesic drug butorphanol tartrate has proved useful clinically in horses and dogs but its analgesic profile had not yet been investigated in sheep. This study was initiated to determine the thermal and mechanical antinociceptive activity of butorphanol (at the dose rates 0.05, 0.1 and 0.2 mg kg-1) in sheep. The drug produced significant analgesia in the thermal lest system, the duration of which was dose related but no significant elevation in mechanical pressure thresholds could be detected. In a further set of experiments the dose rate was increased to 0.4 mg kg-1 and mechanical testing was repeated. There was still no clinically significant elevation in pressure thresholds. At a dose rate of 0.2 mg kg-1 the drug had no detectable effect on respiratory blood gas tensions. Behavioural changes were severe if a dose rate of 0.2 mg kg-1 was exceeded. 7 NAL Call. No.: SF951.E62 The analgesic effect of ketoprofen for use in treating equine colic as compared to flunixin meglumine. Betley, M.; Sutherland, S.F.; Gregoricka, M.J.; Pollet, R.A. Santa Barbara, Calif. : Veterinary Practice Publishing Company; 1991 Jun. Equine practice v. 13 (6): p. 11-16; 1991 Jun. Includes references. Language: English Descriptors: Horses; Colic; Medical treatment; Analgesics; Flunixin; Pain; Drug effects; Antiinflammatory agents 8 NAL Call. No.: 41.8 R312 Analgesic effects of detomidine in thoroughbred horses with chronic tendon injury. Chambers, J.P.; Livingston, A.; Waterman, A.E.; Goodship, A.E. London : British Veterinary Association; 1993 Jan. Research in veterinary science v. 54 (1): p. 53-56; 1993 Jan. Includes references. Language: English Descriptors: Horses; Detomidine; Tendons; Legs; Trauma; Pain Abstract: This study was undertaken to assess the analgesia provided by detomidine (20 micrograms kg-1 intravenously) in thoroughbred horses. Pain thresholds to a mechanical noxious stimulus were measured before and after a period of mild chronic pain in one foreleg. Detomidine was a good analgesic in control animals, their pain thresholds were significantly elevated for about 60 minutes. After injury, the injured leg had a significantly lower pain threshold and the intensity and duration of analgesia provided by detomidine were significantly reduced. The analgesia in the opposite (sound) leg was also reduced, indicating that there were both central and peripheral aspects to this increased sensitivity to painful stimuli. Detomidine deserves to be considered as a potent analgesic in the horse rather than a sedative with analgesic side effects. 9 NAL Call. No.: 41.8 AU72 Analgesic therapy of beak-trimmed chickens. Glatz, P.C.; Murphy, L.B.; Preston, A.P. Brunswick, Victoria : Australian Veterinary Association; 1992 Jan. Australian veterinary journal v. 69 (1): p. 18; 1992 Jan. Includes references. Language: English Descriptors: Fowls; Debeaking; Analgesics; Animal welfare; Feed intake 10 NAL Call. No.: SF914.A53 1990 Anesthesia & analgesia in swine. Swindle, M.M. Columbia, Md. : American College of Laboratory Animal Medicine, 1990? :.; 1990. Anesthesia and analgesia in laboratory animals : proceedings -- 1990 Forum, American College of Laboratory Animal Medicine, Columbia Inn, Columbia, Maryland, May 3-6, 1990. p. 79-87; 1990. Includes references. Language: English Descriptors: Miniature pigs; Anesthesia; Analgesics 11 NAL Call. No.: SF911.V43 Anesthesia and cardiopulmonary bypass technique in calves and sheep. Holmberg, D.L.; Olsen, D.B. Philadelphia, Pa. : J.B. Lippincott Co; 1987 Nov. Veterinary surgery v. 16 (6): p. 463-465; 1987 Nov. Includes references. Language: English Descriptors: Calves; Sheep; Anesthesia; Heart; Lungs; Surgical operations 12 NAL Call. No.: SF601.A46 Anesthesia for the equine orthopedic patient. Muir, W.W. III Lexington, Ky. : The Association; 1992. Proceedings of the annual convention of the American Association of Equine Practitioners (37): p. 721-733; 1992. Meeting held December 1-4, 1991, San Francisco, California. Includes references. Language: English Descriptors: Horses; Anesthetics; Hemodynamics; Postoperative complications 13 NAL Call. No.: SF911.V43 Anesthesia in the llama. Riebold, T.W.; Kaneps, A.J.; Schmotzer, W.B. Hagerstown, Md. : J.B. Lippincott Company; 1989 Sep. Veterinary surgery v. 18 (5): p. 400-404; 1989 Sep. Includes references. Language: English Descriptors: Llamas; Anesthesia; Anesthetics 14 NAL Call. No.: SF601.V535 Anesthesia techniques in sheep and goats. Ewing, K.K. Philadelphia, Pa. : W.B. Saunders Company; 1990 Nov. The Veterinary clinics of North America : food animal practice v. 6 (3): p. 759-778; 1990 Nov. In the series analytic: Advances in sheep and goat medicine / edited by M. C. Smith. Includes references. Language: English Descriptors: Sheep; Goats; Anesthesia; Anesthetics; Analgesics 15 NAL Call. No.: 41.8 M69 The anesthetic and analgesic effects of Telazol and xylazine in pigs: evaluating clinical trials. Thurmon, J.C.; Benson, G.J.; Tranquilli, W.J.; Olson, W.A.; Tracy, C.H. Lenexa, Kan. : Veterinary Medicine Publishing Company; 1988 Aug. Veterinary medicine v. 83 (8): p. 841-845; 1988 Aug. Includes references. Language: English Descriptors: Pigs; Anesthesia; Xylazine; Anesthetics; Analgesics; Drug combinations 16 NAL Call. No.: SF951.V47 Anesthetic complications in the horse. Klein, L. Philadelphia, Pa. : W.B. Saunders; 1990 Dec. The Veterinary clinics of North America : equine practice v. 6 (3): p. 665-692; 1990 Dec. Includes references. Language: English Descriptors: Horses; Anesthesia; Equipment; Failure; Anesthetics; Ventilation; Complications; Cardiovascular system; Hypotension; Hypothermia; Hypoxia; Hyperthermia; Cardiac rhythm; Muscular diseases 17 NAL Call. No.: SF601.A46 Anesthetic considerations for dystocia and caesarean section in mares. Hodgson, D.S. Manhattan, Kan. : The Association; 1989. Proceedings of the annual convention of the American Association of Equine Practitioners (34th): p. 543-547; 1989. Meeting held December 4-7, 1988, San Diego, CA. Includes references. Language: English Descriptors: Mares; Foaling; Anesthesia; Dystocia; Caesarean section; Techniques; Anesthetics 18 NAL Call. No.: SF951.V47 Anesthetic considerations for emergency equine abdominal surgery. Grandy, J.L.; Hodgson, D.S. Philadelphia, Pa. : W.B. Saunders; 1988 Apr. The Veterinary clinics of North America : equine practice v. 4 (1): p. 63-78. ill; 1988 Apr. In the series analytic: Management of colic / edited by S.M. Stover. Literature review. Includes references. Language: English Descriptors: Horses; Abdomen; Anesthesia; Emergencies; Monitoring; Surgery 19 NAL Call. No.: SF951.E62 Anesthetic considerations in equine orthopedics. Short, C.E.; Stauffer, J.L. Santa Barbara, Calif. : Veterinary Practice Pub. Co; 1988 Apr. Equine practice v. 10 (4): p. 43-49; 1988 Apr. Includes references. Language: English Descriptors: Horses; Anesthesia; Orthopedics; Surgery 20 NAL Call. No.: 41.8 AM3 Anesthetic management of an incisional dehiscence in recovery following exploratory laparotomy in a horse. Curtis, M.B.; Eicker, S.W.; Archer, R.M.; Lindsay, W.A. Schaumburg, Ill. : The Association; 1992 Mar01. Journal of the American Veterinary Medical Association v. 200 (5): p. 692-695; 1992 Mar01. Includes references. Language: English Descriptors: Horses; Anesthesia; Laparotomy; Postoperative complications; Case reports 21 NAL Call. No.: 41.8 AM3 Anesthetic management of ostriches. Cornick, J.L.; Jensen, J. Schaumburg, Ill. : The Association; 1992 Jun01. Journal of the American Veterinary Medical Association v. 20 (11): p. 1661-1666; 1992 Jun01. Includes references. Language: English Descriptors: Ostriches; Anesthesia; Anesthetics; Heart rate; Respiration rate; Blood pressure; Blood; Gases; Complications 22 NAL Call. No.: 442.8 B5236 The anesthetic nitrous oxide affects dioxygen utilization by bovine heart and bean seed mitochondrial particles. Sowa, S.; Dong, A.; Roos, E.E.; Caughey, W.S. Duluth, Minn. : Academic Press; 1987 Apr29. Biochemical and biophysical research communications v. 144 (2): p. 643-648; 1987 Apr29. Includes references. Language: English Descriptors: Anesthetics; Nitrous oxide; Cattle; Heart; Beans; Seeds; Mitochondria; Cytochrome c; Substrates; Cytochrome c oxidase; Seed dormancy; Seed germination 23 NAL Call. No.: 41.8 M69 Anesthetics and surgical techniques useful in the potbellied pig. Braun, W. Jr Lenexa, Kan. : Veterinary Medicine Publishing Co; 1993 May05. Veterinary medicine v. 88 (5): p. 441-447; 1993 May05. Includes references. Language: English Descriptors: Miniature pigs; Anesthesia; Anesthetics; Surgical operations 24 NAL Call. No.: QL750.A6 Animal suffering: the appraisal and control of depression and distress in livestock. Fraser, A.F. Amsterdam : Elsevier Science Publishers, B.V.; 1988 Jul. Applied animal behaviour science v. 20 (1/2): p. 127-133; 1988 Jul. Paper presented at the "Symposium on Animal Bio-ethics and Applied Ethology," August 1987, Montreal, Canada. Includes references. Language: English Descriptors: Animal welfare; Pain; Stress; Abnormal behavior; Depression; Bioethics 25 NAL Call. No.: SF910.P34A55 1992 Antinociceptive effects of intrathecal opioids and alpha 2-agonists in sheep. Livingston, A.; Waterman, A.E.; Bouchenafa, O.; Kyles, A. New York : Churchill Livingstone; 1992. Animal pain / edited by Charles E. Short, Alan Van Poznak. p. 281-291, 312; 1992. Includes references. Language: English Descriptors: Sheep; Agonists; Opioids; Drug effects; Analgesics; Testing; Anesthesia; Dosage; Xylazine; Catheterization 26 NAL Call. No.: 41.8 AM3 Arterial blood gas tensions in the horse during recovery from anesthesia. Mason, D.E.; Muir, W.W.; Wade, A. Schaumburg, Ill. : The Association; 1987 Apr15. Journal of the American Veterinary Medical Association v. 190 (8): p. 989-994; 1987 Apr15. Includes references. Language: English Descriptors: Horses; Anesthesia; Oxygen; Internal pressure; Respiratory gases; Ph; Halothane; Position 27 NAL Call. No.: SF955.E6 Arterial blood Po2 and Pco2 in horses during early halothane-oxygen anaesthesia. Grandy, J.L.; Steffey, E.P.; Miller, M. London : British Equine Veterinary Association; 1987 Jul. Equine veterinary journal v. 19 (4): p. 314-318; 1987 Jul. Includes references. Language: English Descriptors: Horses; Anesthesia; Halothane; Oxygen; Arteries; Blood pressure 28 NAL Call. No.: 41.8 AM3A Arterial hypotension and the development of postanesthetic myopathy in halothane-anesthetized horses. Grandy, J.L.; Steffey, E.P.; Hodgson, D.S.; Woliner, M.J. Schaumburg, Ill. : American Veterinary Medical Association; 1987 Feb. American journal of veterinary research v. 48 (2): p. 192-197; 1987 Feb. Includes references. Language: English Descriptors: Horses; Hypotension; Muscular diseases; Halothane; Adverse effects; Anesthesia 29 NAL Call. No.: SF955.E6 Arterial-alveolar carbon dioxide tension difference and alveolar dead space in halothane anaesthetised horses. Moens, Y. Newmarket : R & W Publications; 1989 Jul. Equine veterinary journal v. 21 (4): p. 282-284; 1989 Jul. Includes references. Language: English Descriptors: Horses; Anesthesia; Halothane; Arteries; Carbon dioxide; Tension 30 NAL Call. No.: 41.8 V641 An assessment of carbon dioxide stunning in pigs. Gregory, N.G.; Moss, B.W.; Leeson, R.H. London : British Veterinary Association; 1987 Nov28. The Veterinary record v. 121 (22): p. 517-518; 1987 Nov28. Includes references. Language: English Descriptors: Pigs; Abattoirs; Carbon dioxide; Stunning; Vocalization; Anesthesia; Reflexes; Carcass quality; Animal welfare; Stress 31 NAL Call. No.: 41.8 R312 Assessment of pain associated with degenerative hip disorders in adult male turkeys. Duncan, I.J.H.; Beatty, E.R.; Hocking, P.M.; Duff, S.R.I. London : British Veterinary Association; 1991 Mar. Research in veterinary science v. 50 (2): p. 200-203; 1991 Mar. Includes references. Language: English Descriptors: Turkeys; Hips; Degeneration; Joint diseases; Pain; Betamethasone; Physical activity 32 NAL Call. No.: SF955.E6 Atelectasis causes gas exchange impairment in the anaesthetised horse. Nyman, G.; Funkquist, B.; Kvart, C.; Frostell, C.; Tokics, L.; Strandberg, A.; Lundquist, H.; Lundh, B.; Brismar, B.; Hedenstierna, G. Newmarket : R & W Publications; 1990 Sep. Equine veterinary journal v. 22 (5): p. 317-324; 1990 Sep. Includes references. Language: English Descriptors: Horses; Anesthesia; Computed tomography; Atelectasis; Respiratory disorders; Gas exchange; Lungs 33 NAL Call. No.: SF911.V43 Atracurium as an adjunct to halothane-oxygen anesthesia in a llama undergoing intraocular surgery: a case report. Donaldson, L.L.; Holland, M.; Koch, S.A. Hagerstown, Md. : J.B. Lippincott Company; 1992 Jan. Veterinary surgery v. 21 (1): p. 76-79; 1992 Jan. Includes references. Language: English Descriptors: Llamas; Anesthesia; Surgical operations; Eyes; Halothane; Oxygen; Case reports 34 NAL Call. No.: 41.8 AM3A Auditory brain stem response testing in anesthetized horses. Rolf, S.L.; Reed, S.M.; Melnick, W.; Andrews, F.M. Schaumburg, Ill. : American Veterinary Medical Association; 1987 Jun. American journal of veterinary research v. 48 (6): p. 910-914. ill; 1987 Jun. Includes references. Language: English Descriptors: Horses; Brain stem; Anesthesia; Responses; Testing; Electrical activity 35 NAL Call. No.: SF601.I4 Auriculo palpebral and palpebral nerve blocks in the horse. Bedford, P. London : British Veterinary Association; 1987 Mar. In practice v. 9 (2): p. 63. ill; 1987 Mar. Language: English Descriptors: Horses; Eyes (animal); Peripheral nerves; Blockage; Analgesics; Ophthalmoscopy 36 NAL Call. No.: SF910.P34A55 1992 The balloon model for controlled abdominal pain in the horse. Lowe, J.E. New York : Churchill Livingstone; 1992. Animal pain / edited by Charles E. Short, Alan Van Poznak. p. 408-410, 432; 1992. Includes references. Language: English Descriptors: Horses; Surgical operations; Pain; Abdomen; Models; Balloons; Apparatus; Surgical equipment 37 NAL Call. No.: QL750.A6 Behavioural evidence for persistant pain following partial beak amputation in chickens. Gentle, M.J.; Waddington, D.; Hunter, L.N.; Jones, R.B. Amsterdam : Elsevier Science Publishers, B.V.; 1990 Aug. Applied animal behaviour science v. 27 (1/2): p. 149-157; 1990 Aug. Includes references. Language: English Descriptors: Hens; Debeaking; Pain; Behavior change; Drinking water; Temperature 38 NAL Call. No.: 41.8 AM3 Bilateral arytenoid cartilage paralysis after inhalation anesthesia in a horse. Abrahamsen, E.J.; Bohanon, T.C.; Bednarski, R.M.; Hubbell, J.A.E.; Muir, W.W. III Schaumburg, Ill. : The Association; 1990 Nov15. Journal of the American Veterinary Medical Association v. 197 (10): p. 1363-1365; 1990 Nov15. Includes references. Language: English Descriptors: Horses; Anesthesia; Adverse effects; Paralysis; Larynx; Case studies; Peripheral nerves 39 NAL Call. No.: 41.8 V643 Biopsy of the bovine mammary gland. Knight, C.H.; Hillerton, J.E.; Teverson, R.M.; Winter, A. London : Bailliere Tindall; 1992 Mar. British veterinary journal v. 148 (2): p. 129-132; 1992 Mar. Includes references. Language: English Descriptors: Dairy cows; Mammary glands; Biopsy; Milk yield Abstract: A technique is described for biopsy of the bovine udder, employing sedation and local anaesthesia. Tissue samples of approximately 5 g were obtained by electrocautery from two quarters of the udder of a cow laterally recumbent. Care was taken to ensure complete haemostasis which was achieved by electrocoagulation and ligation. Postoperative recovery was rapid, and loss of yield was no greater in biopsied glands than in control glands of the same cow. Yield from all quarters returned to preoperative levels within 48 h. 40 NAL Call. No.: 41.8 AM3 Blood pressure response to tourniquet use in anesthetized horses. Copland, V.S.; Hildebrand, S.V.; Hill, T. III; Wong, P.; Brock, N. Schaumburg, Ill. : The Association; 1989 Oct15. Journal of the American Veterinary Medical Association v. 195 (8): p. 1097-1103; 1989 Oct15. Includes references. Language: English Descriptors: Horses; Anesthesia; Surgery; Veterinary equipment; Blood pressure 41 NAL Call. No.: 41.8 R312 Bronchoalveolar lavage of the live anaesthetised sheep. Burrells, C.; Williams, J.T. London : British Veterinary Association; 1987 Jan. Research in veterinary science v. 42 (1): p. 109-112. ill; 1987 Jan. Includes references. Language: English Descriptors: Sheep; Bronchi; Washing; Laboratory techniques; Anesthesia; Catheters; Endoscopy; Body fluids; Leukocytes 42 NAL Call. No.: SF951.E62 Butorphanol or xylazine premedication with halothane anesthesia in the horse. Matthews, N.S.; Smith, J.R.; Gallagher, L.V. Santa Barbara, Calif. : Veterinary Practice Pub. Co; 1987 Mar. Equine practice v. 9 (3): p. 7-11; 1987 Mar. Includes references. Language: English Descriptors: Horses; Anesthesia; Halothane; Xylazine; Blood pressure; Blood ph; Gases 43 NAL Call. No.: 41.8 AU72 Caecal overload and rupture in the horse. Hilbert, B.J.; Little, C.B.; Bolton, J.R.; McGill, C.A. Brunswick, Victoria : Australian Veterinary Association; 1987 Mar. Australian veterinary journal v. 64 (3): p. 85-86; 1987 Mar. Includes references. Language: English Descriptors: Horses; Cecum; Rupture; Anesthesia; Intestine motility 44 NAL Call. No.: SF911.V43 Capnographic monitoring during anesthesia with controlled ventilation in the horse. Cribb, P.H. Philadelphia, Pa. : J.B. Lippincott Co; 1988 Jan. Veterinary surgery v. 17 (1): p. 48-52; 1988 Jan. Includes references. Language: English Descriptors: Horses; Anesthesia; Monitoring; Ventilation 45 NAL Call. No.: 41.8 AM3A Cardiopulmonary effects of a tiletamine-zolazepam combination in sheep. Lagutchik, M.S.; Januszkiewicz, A.J.; Dodd, K.T.; Martin, D.G. Schaumburg, Ill. : American Veterinary Medical Association; 1991 Sep. American journal of veterinary research v. 52 (9): p. 1441-1447; 1991 Sep. Includes references. Language: English Descriptors: Sheep; Injectable anesthetics; Anesthesia; Heart; Lungs; Physiological functions Abstract: To assess the effects on heart and lung function, a tiletamine-zolazepam (TZ) anesthetic combination was evaluated in 10 Dorset-type ewes. Ewes were randomly allotted to 2 equal groups. Ewes of groups 1 and 2 were given a single bolus of TZ (12 and 24 mg/kg of body weight, IV, respectively) at time zero. Hemodynamic, pulmonary, and ventilation variables were measured at 15-minute intervals to 120 minutes. Blood gas variables were evaluated at 5-minute intervals for the first 30 minutes, then at 15-minute intervals to 120 minutes. In all sheep, TZ administration induced rapid, smooth induction, with gradual and unremarkable recovery. Anesthesia duration was not significantly different between groups (mean +/- SD, 39 +/- 5 and 40 +/- 14 minutes for groups 1 and 2, respectively). Immediate drug effects included apnea, decreased mean arterial blood pressure, and arterial hypoxemia. Cardiac output was significantly decreased in both groups at all times after drug administration. Significant changes in group-1 ewes included increased pulmonary and systemic vascular resistances and decreased inspired minute ventilation, tidal volume, and respiratory airflow. Significant changes in group-2 ewes included increased systemic vascular resistance and decreased pulmonary arterial pressure, inspired minute ventilation, and respiratory airflow. Both drug dosages induced apneustic breathing patterns and caused significant changes in arterial and venous blood hemoglobin concentrations and PCV. Tiletamine-zolazepam is useful for intermediate-duration anesthesia in sheep. However, because of alterations in cardiopulmonary function, its use at the dosages evaluated by us is not recommended in studies, in which minimal effects on heart and lung function are required, or in sheep with compromised heart or lung function. 46 NAL Call. No.: SF915.J63 Cardiopulmonary effects of ephedrine in halothane-anesthetized horses. Grandy, J.L.; Hodgson, D.S.; Dunlop, C.I.; Chapman, P.L.; Heath, R.B. Oxford : Blackwell Scientific Publications; 1989 Dec. Journal of veterinary pharmacology and therapeutics v. 12 (4): p. 389-396; 1989 Dec. Includes references. Language: English Descriptors: Horses; Ephedrine; Halothane; Anesthesia; Cardiac output; Blood pressure 47 NAL Call. No.: SF955.E6 Cardiopulmonary effects of epidurally administered xylazine in the horse. Leblanc, P.H.; Eberhart, S.W. Newmarket : R & W Publications; 1990 Nov. Equine veterinary journal v. 22 (6): p. 389-391; 1990 Nov. Includes references. Language: English Descriptors: Horses; Cardiovascular system; Xylazine; Analgesics; Conduction anesthesia; Blood pressure 48 NAL Call. No.: 410.9 P94 Cardiopulmonary effects of nalbuphine hydrochloride and butorphanol tartrate in sheep. O'Hair, K.O.; Dodd, K.T.; Phillips, Y.Y.; Beattie, R.J. Cordova, Tenn. : American Association for Laboratory Animal Science; 1988 Feb. Laboratory animal science v. 38 (1): p. 58-61; 1988 Feb. Includes references. Language: English Descriptors: Sheep; Analgesics; Drug effects; Cardiovascular system; Respiration Abstract: The cardiopulmonary, sedative and analgesic effects of butorphanol tartrate and nalbuphine hydrochloride were evaluated in six adult crossbred Dorset sheep (Ovis aries). The animals were divided randomly into two groups of three. The first group received butorphanol tartrate (o.5mg/Kg s.c.) followed in three days by nalbuphine hydrochloride (Img/Kg, s.c.). The second group received nalbuphine followed in three days by butorphanol. Cardiopulmonary parameters were evaluated at baseline (once the animal had accomodated to restraint); immediately following analgesic administration; and at 15, 30, 60, 90 and 120 minutes after analgesic administration. No significant changes (alpha greater than .05) from baseline were seen inany of the measured cardiopulmonary parameters from either the butorphanol or nalbuphine groups. Butorphanol produced the most dramatic analgesic and sedative effects with onset of both within 15 minutes of administration and peak effects occurring 30 minutes post injection. The degree of analgesia was diminished at 120 minutes while the sedative effect returned to near baseline by 90 minutes. The nalbuphine group also showed an onset of analgesia 15 minutes post injection reaching a peak effect after 30 minutes. However, onset of sedation occurred 30 minutes post injection achieving a peak effect at 60 minutes which was markedly less than that of butorphanol. As in the butorphanol group, analgesia was diminished at 120 minutes. 49 NAL Call. No.: SF955.E6 Cardiopulmonary effects of xylazine sedation in the foal. Carter, S.W.; Robertson, S.A.; Steel, C.J.; Jourdenais, D.A. Newmarket : R & W Publications; 1990 Nov. Equine veterinary journal v. 22 (6): p. 384-388; 1990 Nov. Includes references. Language: English Descriptors: Horses; Foals; Cardiovascular system; Xylazine; Analgesics 50 NAL Call. No.: SF915.J63 Cardiopulmonary function during 5 hours of constant-dose isoflurane in laterally recumbent, spontaneously breathing horses. Steffey, E.P.; Hodgson, D.S.; Dunlop, C.I.; Miller, M.F.; Woliner, M.J.; Heath, R.B.; Grandy, J. Oxford : Blackwell Scientific Publications; 1987 Dec. Journal of veterinary pharmacology and therapeutics v. 10 (4): p. 290-297; 1987 Dec. Includes references. Language: English Descriptors: Horses; Anesthesia; Anesthetics; Respiration; Heart output; Drug effects 51 NAL Call. No.: SF910.P34A55 1992 Cardiorespiratory and MAC-reducing effects of alpha-2-adrenoreceptoragonists in horses. Muir, W.W.; Wagner, A.E.; Hinchcliff, K.W. New York : Churchill Livingstone; 1992. Animal pain / edited by Charles E. Short, Alan Van Poznak. p. 102-212; 1992. Includes references. Language: English Descriptors: Horses; Agonists; Analgesics; Drug effects; Anesthetics; Heart rate; Cardiovascular system; Respiratory system; Xylazine; Alpha-adrenergic receptors 52 NAL Call. No.: SF915.J63 Cardiovascular and allied acations of xylazine and atropine in the unanaesthetized goat. Kokkonen, U.M.; Eriksson, L. Oxford : Blackwell Scientific Publications; 1987 Mar. Journal of veterinary pharmacology and therapeutics v. 10 (1): p. 11-16; 1987 Mar. Includes references. Language: English Descriptors: Goats; Xylazine; Atropine; Anesthetics; Adverse effects; Cardiovascular system 53 NAL Call. No.: 41.8 AM3A Cardiovascular and respiratory effects of inspired oxygen fraction in halothane-anesthetized horses. Cuvelliez, S.G.; Eicker, S.W.; McLauchlan, C.; Brunson, D.B. Schaumburg, Ill. : American Veterinary Medical Association; 1990 Aug. American journal of veterinary research v. 51 (8): p. 1226-1231; 1990 Aug. Includes references. Language: English Descriptors: Horses; Halothane; Anesthesia; Oxygen; Respiratory system; Cardiovascular system Abstract: Anesthesia of equids is associated with pulmonary dysfunction. Cardiovascular and respiratory effects of inhalation anesthetic agents and duration of anesthesia have been studied, using oxygen as the carrier gas. To our knowledge, the effects of inspired oxygen have not been determined. We studied the cardiovascular and respiratory effects of 2 inspired oxygen fractions (0.30 and > 0.85) in 5 laterally recumbent, halothane-anesthetized horses. Mean systemic arterial blood pressure, cardiac output, central venous pressure, pulmonary arterial pressure, arterial pH, and arterial base excess were similar in horses of the 2 groups during 4 hours of anesthesia at constant end-tidal halothane concentration. End-tidal partial pressure of CO2, arterial partial pressure of CO2 and O2, and alveolar-to-arterial O2 tension difference were greater in horses exposed to the higher oxygen concentration. On the basis of the data obtained, we suggest that greater hypoventilation and ventilation/perfusion mismatch occur when horses are breathing high-oxygen fraction. Arterial partial pressure of O2 was not different between the 2 groups of horses after they were disconnected from the anesthesia circuit and allowed to breathe room air. Horses recovered from anesthesia without complications. 54 NAL Call. No.: 41.8 AM3A Cardiovascular and respiratory measurementss in awake and isoflurane-anesthetized horses. Steffey, E.P.; Dunlop, C.I.; Farver, T.B.; Woliner, M.J.; Schultz, L.J. Schaumburg, Ill. : American Veterinary Medical Association; 1987 Jan. American journal of veterinary research v. 48 (1): p. 7-12; 1987 Jan. Includes references. Language: English Descriptors: Horses; Anesthetics; Anesthesia; Oxygen; Blood pressure; Heart output; Heart rate; Respiration rate 55 NAL Call. No.: 410.9 P94 Cardiovascular effects of a ketamine-medetomidine combination that produces deep sedation in Yucatan mini swine. Vainio, O.M.; Bloor, B.C.; Kim, C. Cordova, Tenn. : American Association for Laboratory Animal Science; 1992 Dec. Laboratory animal science v. 42 (6): p. 582-588; 1992 Dec. Includes references. Language: English Descriptors: Miniature pigs; Anesthetics; Cardiovascular system Abstract: Seven chronically instrumented Yucatan minipigs were deeply sedated with the combination of ketamine (10 mg/kg), a dissociative anesthetic, and medetomidine (0.2 mg/kg), an alpha 2-adrenoceptor agonist used as an animal sedative in Europe. Both drugs were drawn in the same syringe and administered in the left atrium via a previously inserted permanent catheter. As a result, hypertension (mean arterial pressure from 116 +/- 12 mmHg to 142 +/- 18 mmHg) occurred and was followed by bradycardia (from 107 +/- 22 bpm to 71 +/- 9 bpm). Concomitantly both the rate of increase in ventricular pressure (48%) and ventricular wan thickening fraction (37%) decreased, thus indicating some worsening of left ventricular function. Further, systemic vascular resistance increased (290%) resulting in a reduction in cardiac output from 1.8 +/- 0.7 l/minute to 0.4 +/- 0.3 l/minute. Also, left ventricular end diastolic pressure initially increased (maximum 10.2 +/- 10.8 mmHg) but returned to the control level in 5 minutes. In spite of an increase in respiratory frequency (3x), PaCO2 increased and PaO2 and pH declined. Rectal temperature decreased from 38.4 +/- 0.9 to 36.0 +/- 0.8 degrees C. All of these changes were transient and returned to control levels during the follow-up period (2 hours). However, epinephrine concentration was exceptionally decreased by the drugs and stayed under the detection limit (20 pg/kg) for the entire time, whereas norepinephrine was undetectable for 10 minutes postadministration. Ketamine-medetomidine, administered in a dose that produced deep sedation, induced marked but reversible changes in most of the cardiovascular variables; there were no pedal or palpebral reflexes for 30 minutes. 56 NAL Call. No.: SF911.V43 Cardiovascular effects of intravenous sodium penicillin, sodium cefazolin, and sodium citrate in awake and anesthetized horses. Hubbell, J.A.E.; Muir, W.W.; Robertson, J.T.; Sams, R.A. Philadelphia, Pa. : J.B. Lippincott Co; 1987 May. Veterinary surgery v. 16 (3): p. 245-250; 1987 May. Includes references. Language: English Descriptors: Horses; Anesthesia; Cardiovascular system; Injections; Sodium citrate; Penicillins; Cefazolin; Drug effects 57 NAL Call. No.: 41.8 R312 Cardiovascular effects recorded in horses during anaesthesia after treatment with trichlorfon. Adams, J.G.; Trim, C.M. London : British Veterinary Association; 1989 Sep. Research in veterinary science v. 47 (2): p. 164-169; 1989 Sep. Includes references. Language: English Descriptors: Horses; Anesthesia; Cardiovascular system; Trichlorfon; Anthelmintics; Blood pressure 58 NAL Call. No.: SF911.V43 The cardiovascular response of sheep to tiletamine-zolazepam and butorphanol tartrate anesthesia. Howard, B.W.; Lagutchik, M.S.; Januszkiewicz, A.J.; Martin, D.G. Hagerstown, Md. : J.B. Lippincott Company; 1990 Nov. Veterinary surgery v. 19 (6): p. 461-467; 1990 Nov. Includes references. Language: English Descriptors: Ewes; Diazepam; Anesthetics; Ketamine 59 NAL Call. No.: SF601.I4 Caudal epidural anaesthesia in the ewe. Harris, T. London : British Veterinary Association; 1991 Nov. In practice v. 13 (6): p. 234-235; 1991 Nov. Includes references. Language: English Descriptors: Ewes; Anesthesia 60 NAL Call. No.: SF601.C24 Caudal epidural analgesia in cattle using xylazine. Caron, J.P.; LeBlanc, P.H. Ottawa : Canadian Veterinary Medical Association; 1989 Oct. Canadian journal of veterinary research; Revue canadienne de recherche veterinaire v. 53 (4): p. 486-489; 1989 Oct. Includes references. Language: English Descriptors: Cows; Xylazine; Conduction anesthesia; Dosage; Duration; Perineum 61 NAL Call. No.: 41.8 AM3A Caudal epidural analgesia induced by xylazine administration in cows. St Jean, G.; Skarda, R.T.; Muir, W.W.; Hoffsis, G.F. Schaumburg, Ill. : American Veterinary Medical Association; 1990 Aug. American journal of veterinary research v. 51 (8): p. 1232-1236; 1990 Aug. Includes references. Language: English Descriptors: Cows; Xylazine; Ataxia; Cardiovascular system; Respiratory system; Rumen motility; Drug effects; Adverse effects Abstract: Xylazine (0.05 mg/kg of body weight diluted to a 5-ml volume, using 0.9% NaCl) or 5 ml of 0.9% NaCl was administered epidurally into the first caudal intervertebral space (Co1-Co2) in 8 cows (mean +/- SD body weight, 583 +/- 150 kg). Cows were observed for responses to deep needle pricking of the caudal dermatomes (S3 to Co), sedation, and ataxia. Heart rate, respiratory rate, body temperature, rate of ruminal contractions, coccygeal arterial blood pressure, pHa, blood gas tension (Pa(O2), Pa(CO2)), base excess, total solids concentration, and PCV were determined before and after xylazine administration. Epidurally administered xylazine induced sedation and selective (S3 to Co) analgesia for at least 2 hours. Mild ataxia of hind limbs was observed in 6 cows, but all cows remained standing. Heart rate, respiratory rate, rate of ruminal contractions, arterial blood pressure, Pa(O2), PCV, and total solids concentration were significantly (P < 0.05) decreased, and Pa(CO2), base excess, and bicarbonate concentration were significantly (P < 0.05) increased after xylazine administration. Epidurally administered 0.9% NaCl did not alter sensory perception to needle pricking and did not affect any of the physiologic variables determined. Although epidural administration of xylazine induced analgesia and sedation in healthy cows, it should be avoided for epidural analgesia in cattle with heart disease, lung disease, and/or gastrointestinal disease because of its potent cardiopulmonary and ruminal depressant effects. 62 NAL Call. No.: SF951.E62 Challenge in equine anesthesia: a suspected allergic reaction during acetylpromazine, guaifenesin, thiamylal, and halothane anesthesia. Goldberg, G.P.; Short, C.E. Santa Barbara, Calif. : Veterinary Practice Pub. Co; 1988 Feb. Equine practice v. 10 (2): p. 5-10. ill; 1988 Feb. Includes references. Language: English Descriptors: Horses; Anesthesia; Allergies; Diagnostic techniques; Halothane; Guaifenesin; Anesthetics; Adverse effects 63 NAL Call. No.: 41.8 C81 Changes in equine carpal joint synovial fluid in response to the injection of two local anesthetic agents. White, K.K.; Hodgson, D.R.; Hancock, D.; Parry, B.W.; Cordell, C. Ithaca, N.Y. : Cornell Veterinarian, Inc; 1989 Jan. Cornell veterinarian v. 79 (1): p. 25-38; 1989 Jan. Includes references. Language: English Descriptors: Horses; Lidocaine; Anesthetics; Injections; Carpus; Joints (animal); Synovial fluid 64 NAL Call. No.: SF910.P34A55 1992 Changes in nociceptive thresholds associated with chronic pain in sheep. Waterman, A.E.; Livingston, A.; Ley, S.J.; Brandt, S. New York : Churchill Livingstone; 1992. Animal pain / edited by Charles E. Short, Alan Van Poznak. p. 378-385, 400; 1992. Includes references. Language: English Descriptors: Sheep; Pain; Central nervous system; Testing; Animal experiments; Laboratory tests 65 NAL Call. No.: SF601.J6 Changes of blood values in Przewalski horses (Equus przewalski przewalski) and zebras (Equus zebra hartmannae) during chemical immobilization. Kuttner, C.; Wiesner, H. Lawrence, Kan. : The Journal; 1987. The Journal of zoo animal medicine v. 18 (4): p. 144-147; 1987. Includes references. Language: English Descriptors: Przewalski's horse; Zebras; Blood chemistry; Anesthesia; Immobilization; Neuroleptics 66 NAL Call. No.: 41.8 V641 Chemical immobilisation in ostriches (Struthio camelus) using etorphine hydrochloride. Samour, J.H.; Irwin-Davies, J.; Faraj, E. London : The Association; 1990 Dec08. The Veterinary record : journal of the British Veterinary Association v. 127 (23): p. 575-576. ill; 1990 Dec08. Includes references. Language: English Descriptors: Ostriches; Immobilization; Etorphine; Anesthesia 67 NAL Call. No.: SF951.V47 Chemical restraint and analgesia in the horse. Geiser, D.R. Philadelphia, Pa. : W.B. Saunders; 1990 Dec. The Veterinary clinics of North America : equine practice v. 6 (3): p. 495-512; 1990 Dec. Includes references. Language: English Descriptors: Horses; Draft animals; Anesthetics; Anesthesia; Neuroleptics; Restraint of animals; Chloral hydrate; Opioids; Analgesics; Promazine; Xylazine; Diazepam; Morphine; Pethidine 68 NAL Call. No.: SF601.A46 Chemical restraint and general anesthesia in the draft horse. Geiser, D.R. Manhattan, Kan. : The Association; 1989. Proceedings of the annual convention of the American Association of Equine Practitioners (35th): p. 461-472; 1989. Meeting held December 3-6 1989, Boston, Massachusetts. Includes references. Language: English Descriptors: Horses; Draft animals; Anesthesia; Anesthetics; Restraint of animals 69 NAL Call. No.: QL750.E74 Chicks in a novel environment: effects of conspecific calls. Vallortigara, G. Berlin, W. Ger. : Paul Parey; 1988 Aug. Ethology v. 78 (4): p. 341-345; 1988 Aug. Includes references. Language: English Descriptors: Chicks; Environment; Vocalization; Stress; Animal behavior 70 NAL Call. No.: SF910.P34A55 1992 Clinical assessment of analgesic effects of butorphanol in cattle. Dodman, N.H.; Levine, H.; Court, M.H. New York : Churchill Livingstone; 1992. Animal pain / edited by Charles E. Short, Alan Van Poznak. p. 396-399, 401; 1992. Includes references. Language: English Descriptors: Cattle; Analgesics; Drug effects 71 NAL Call. No.: SF955.E6 Clinical evaluation of an infusion of xylazine, guaifenesin and ketamine for maintenance of anaesthesia in horses. Young, L.E.; Bartram, D.H.; Diamond, M.J.; Gregg, A.S.; Jones, R.S. Newmarket : R & W Publications; 1993 Mar. Equine veterinary journal v. 25 (2): p. 115-119; 1993 Mar. Includes references. Language: English Descriptors: Uk; Horses; Xylazine; Anesthesia; Guaifenesin; Ketamine; Surgery 72 NAL Call. No.: SF601.A46 Clinical evaluation of detomidine hydrochloride for equine reproductive surgery. McKinnon, A.O.; Carnevale, E.M.; Squires, E.L.; Jochle, W. Manhattan, Kan. : The Association; 1989. Proceedings of the annual convention of the American Association of Equine Practitioners (34th): p. 563-568; 1989. Meeting held December 4-7, 1988, San Diego, CA. Includes references. Language: English Descriptors: Horses; Surgical operations; Analgesics; Reproductive organs (animal) 73 NAL Call. No.: 41.8 V641 Clinical evaluation of romifidine/ketamine/halothane anaesthesia in horses. Diamond, M.J.; Young, L.E.; Bartram, D.H.; Gregg, A.S.; Clutton, R.E.; Long, K.J.; Jones, R.S. London : The Association; 1993 Jun05. The Veterinary record : journal of the British Veterinary Association v. 132 (23): p. 572-575; 1993 Jun05. Includes references. Language: English Descriptors: Horses; Preanesthetic medication 74 NAL Call. No.: SF601.A46 Clinical experience with isoflurane anesthesia in foals and adult horses. Rose, J.A.; Rose, E.M.; Peterson, P.R. Manhattan, Kan. : The Association; 1989. Proceedings of the annual convention of the American Association of Equine Practitioners (34th): p. 555-561; 1989. Meeting held December 4-7, 1988, San Diego, CA. Includes references. Language: English Descriptors: Horses; Foals; Anesthesia; Halothane; Anesthetics 75 NAL Call. No.: SF915.J63 Clinical investigations of halothane and isoflurane for induction and maintenance of foal anesthesia. Steffey, E.P.; Willits, N.; Wong, P.; Hildebrand, S.V.; Wheat, J.D.; Meagher, D.M.; Hodgson, D.; Pascoe, J.R.; Heath, R.B.; Dunlop, C. Oxford : Blackwell Scientific Publications; 1991 Sep. Journal of veterinary pharmacology and therapeutics v. 14 (3): p. 300-309; 1991 Sep. Includes references. Language: English Descriptors: Foals; Halothane; Inhaled anesthetics; Anesthesia; Safety; Heart rate; Drug effects 76 NAL Call. No.: SF380.I52 Clinical observations in Shami goat kids sedated with medetomidine. Mohammad, F.K.; Zangana, I.K.; Al-Kassim, N.A. New York : Elsevier; 1991 Jul. Small ruminant research v. 5 (1/2): p. 149-153; 1991 Jul. Includes references. Language: English Descriptors: Kids; Anesthetics; Analgesics; Physiological functions; Heart rate; Respiration rate; Body temperature; Rumen motility 77 NAL Call. No.: SF955.E6 Clinical use of epidural xylazine in the horse. LeBlanc, P.H.; Caron, J.P. Newmarket : R & W Publications; 1990 May. Equine veterinary journal v. 22 (3): p. 180-181; 1990 May. Includes references. Language: English Descriptors: Horses; Anesthetics; Conduction anesthesia; Xylazine 78 NAL Call. No.: SF951.V47 Clinical use of positive-pressure ventilation in the horse. Shawley, R.V.; Mandsager, R.E. Philadelphia, Pa. : W.B. Saunders; 1990 Dec. The Veterinary clinics of North America : equine practice v. 6 (3): p. 575-585; 1990 Dec. Includes references. Language: English Descriptors: Horses; Anesthesia; Ventilation; Equipment; Ventilators 79 NAL Call. No.: 41.8 AM3 Clinical use of the neuromuscular blocking agents atracurium and pancuronium for equine anesthesia. Hildebrand, S.V.; Holland, M.; Copland, V.S.; Daunt, D.; Brock, N. Schaumburg, Ill. : The Association; 1989 Jul15. Journal of the American Veterinary Medical Association v. 195 (2): p. 212-219; 1989 Jul15. Includes references. Language: English Descriptors: Horses; Anesthesia; Muscle relaxants; Drug effects; Surgical operations 80 NAL Call. No.: SF911.V43 Closed-circuit liquid injection isoflurane anesthesia in the horse. Olson, K.N.; Klein, L.V.; Nann, L.E.; Soma, L.R. Hagerstown, Md. : J.B. Lippincott Company; 1993 Jan. Veterinary surgery v. 22 (1): p. 73-78; 1993 Jan. Includes references. Language: English Descriptors: Pennsylvania; Horses; Anesthesia; Closed systems; Injection; Liquids; Surgery 81 NAL Call. No.: SF915.J63 Colonic alpha 2-adrenoceptor-mediated responses in the pony. Roger, T.; Ruckebusch, Y. Oxford : Blackwell Scientific Publications; 1987 Dec. Journal of veterinary pharmacology and therapeutics v. 10 (4): p. 310-318. ill; 1987 Dec. Includes references. Language: English Descriptors: Horses; Colon; Intestine motility; Prostaglandins; Xylazine; Analgesics 82 NAL Call. No.: 41.8 V641 A combination of methotrimeprazine, midazolam and guaiphenesin, with and without ketamine, in an anaesthetic procedure for horses. Luna, S.P.L.; Massone, F.; Castro, G.B.; Fantoni, D.T.; Hussni, C.A.; Aguiar, A.J.A. London : The Association; 1992 Jul11. The Veterinary record : journal of the British Veterinary Association v. 131 (2): p. 33-35; 1992 Jul11. Includes references. Language: English Descriptors: Horses; Phenothiazines; Benzodiazepines; Guaifenesin; Ketamine; Anesthesia; Drug combinations; Preanesthetic medication; Halothane; Drug effects; Adverse effects; Cardiovascular system; Respiration 83 NAL Call. No.: SF601.A46 Common complications associated with equine chemical restraint and anesthesia. Muir, W.W. III Manhattan, Kan. : The Association; 1990. Proceedings of the annual convention of the American Association of Equine Practitioners. p. 259-266; 1990. Meeting held December 2-5, 1990, Lexington, KY. Includes references. Language: English Descriptors: Horses; Restraint of animals; Anesthesia; Postoperative complications 84 NAL Call. No.: SF601.I4 Common conditions of domestic pigeons. Wallis, A.S. London : British Veterinary Association; 1991 May. In practice v. 13 (3): p. 95-100; 1991 May. Literature review. Includes references. Language: English Descriptors: Racing pigeons; Animal health; Laboratory diagnosis; Parasites; Treatment; Drugs; Anesthetics; Symptoms 85 NAL Call. No.: 41.8 AM3A Comparative analgesia of xylazine, xylazine/morphine, xylazine/butorphanol, and xylazine/nalbuphine in the horse, using dental dolorimetry. Brunson, D.B.; Majors, L.J. Schaumburg, Ill. : American Veterinary Medical Association; 1987 Jul. American journal of veterinary research v. 48 (7): p. 1087-1091; 1987 Jul. Includes references. Language: English Descriptors: Horses; Analgesics; Pain; Measurement; Teeth; Drug combinations; Xylazine 86 NAL Call. No.: QP251.A1T5 Comparative efficacy of FSH-P and PMSG on superovulation in Pashmina goats. Mahmood, S.; Koul, G.L.; Biswas, J.C. Stoneham, Mass. : Butterworth-Heinemann; 1991 Jun. Theriogenology v. 35 (6): p. 1191-1196; 1991 Jun. Includes references. Language: English Descriptors: Goats; Goat breeds; Superovulation; Fsh; Pmsg; Embryos; Isolation; Survival; Corpus luteum; Age; Conception; Embryo transfer; Anesthesia; Triflupromazine; Barbiturates Abstract: Twenty-eight Pashmina goats were utilized to study the comparative effect of FSH-P and PMSG on superovulatory response. The effect of FSH-P marketed by two commercial firms was compared with respect to the number of corpora lutea and embryos recovered. The difference was found to be nonsignificant. Superovulatory responses with FSH-P (pooled) and PMSG were 16.55 +/- 6.13 and 11.70 +/- 8.07, respectively, and the difference was significant (P<0.02). Recovery of embryos was significantly higher (P<0.001) with FSH-P (4.72 +/- 4.33) than with PMSG (2.50 +/- 5.02) treatment. The superovulatory response (number of corpora lutea) and the embryo recovery rate was better in higher age groups (4 to 6 yr) than younger goats (1.5 to 3 yr). The embryo survival rate was higher (54.54%) for recipients operated on under a basal anaesthetics (Triflupromazine hydrochloride USP) than for those operated on under barbiturate anaesthesia (13.64%). The overall conception rate was 34.09%. 87 NAL Call. No.: SF601.C24 Comparative pharmacokinetics of Yohimbine in steers, horses and dogs. Jernigan, A.D.; Wilson, R.C.; Booth, N.H.; Hatch, R.C.; Akbari, A. Ottawa : Canadian Veterinary Medical Association; 1988 Apr. Canadian journal of veterinary research; Revue canadienne de recherche veterinaire v. 52 (2): p. 172-176; 1988 Apr. Includes references. Language: English Descriptors: Dogs; Horses; Steers; Anesthetics; Indoles; Pharmacokinetics 88 NAL Call. No.: 41.8 AM3A Comparative study of continuous lumbar segmental epidural and subarachnoid analgesia in Holstein cows. Skarda, R.T.; Muir, W.W.; Hubbell, J.A.E. Schaumburg, Ill. : American Veterinary Medical Association; 1989 Jan. American journal of veterinary research v. 50 (1): p. 39-44. ill; 1989 Jan. Includes references. Language: English Descriptors: Dairy cows; Analgesics; Procaine; Administration; Injections; Catheters; Holstein-friesian; Cardiovascular system; Respiratory system Abstract: Eight adult Holstein cows were used to compare the effects of lumbar segmental epidural analgesia (SEA) and lumbar segmental subarachnoid analgesia (SSA). A modified 17-gauge Huber point (Tuohy) needle was used to place a catheter with stylet into either the epidural space at the thoracolumbar (T13-L1) intervertebral space or the tubarachnoid space at the lumbosacral intervertebral junction. The catheters were advanced so that their tips lay at the anterior lumbar (L1-L2) epidural space or at the thoracolumbar (T-13-L1) subarachnoid space. The position of the catheter was confirmed radiographically. A 5% solution of procaine HCl was used at mean doses of 300 mg (6 ml) to induce SEA and 84.4 +/- 12.9 mg (1.7 +/-0.3 ml) to induce SSA. Onset of analgesia to superficial and deep muscular pinprick stimulation was significantly (P less than 0.05) faster in cows with SSA than in those with SEA (10.4 +/- 2.3 minutes vs 15.9 +/- 3.8 minutes). Maximal thoracolumbar analgesia extended from spinal cord segments T12 to L4 on one or both sides of the vertebral column during SEA and from T10 to L3 on one or both sides during SSA. Duration of analgesia lasted significantly (P less than 0.05) longer in cows with SEA than in those with SSA (76.2 +/- 16.2 minutes vs 53.7 +/- 14.3 minutes). The advantages and disadvantages of the SEA catheter technique are discussed. 89 NAL Call. No.: 41.8 AM3A Comparative study of the pharmacokinetics of alfentanil in rabbits, sheep, and dogs. Ilkiw, J.E.; Benthuysen, J.A.; McNeal, D. Schaumburg, Ill. : American Veterinary Medical Association; 1991 Apr. American journal of veterinary research v. 52 (4): p. 581-584; 1991 Apr. Includes references. Language: English Descriptors: Dogs; Sheep; Rabbits; Analgesics; Pharmacokinetics; Species differences; Anesthesia Abstract: The central arterial pharmacokinetics of alfentanil, a short-acting opioid agonist, were studied in rabbits, sheep, and dogs after short-duration infusion of the drug. Alfentanil was infused until a set end point (high-amplitude, slow-wave activity on the EEG) was reached. This required a larger alfentanil dose and a higher alfentanil arterial concentration in sheep, compared with rabbits and dogs. The plasma concentration-time data for each animal were fitted, using nonlinear regression, and in all animals, were best described by use of a triexponential function. In this study, differences in the disposition kinetics of alfentanil among the 3 species were found for only distribution clearance and initial distribution half-life. In dogs, compared with rabbits and sheep, the first distribution half-life was longer, probably because of pronounced drug-induced bradycardia (mean +/- SD, 48 +/-21 beats/min). Distribution clearance was faster in sheep, compared with dogs, also probably because of better blood flow in sheep. Elimination half-life was similar in all species (rabbits, 62.4 +/- 11.3 minutes; sheep, 65.1 +/- 27.1 minutes; dogs, 58.3 +/- 10.3 minutes). This rapid half-life resulted from a small steady-state volume of distribution (rabbits, 908.3 +/- 269.0 ml/kg; sheep, 720.0 +/- 306.7 ml/kg; dogs, 597.7 +/- 290.2 ml/kg) and rapid systemic clearance (rabbits, 19.4 +/- 5.3 ml/min/kg; sheep, 13.3 +/- 3.0 ml/min/kg; dogs, 18.7 +/- 7.5 ml/min/kg). On the basis of these pharmacokinetic variables, alfentanil should have short duration of action in rabbits, sheep, and dogs. This may be beneficial in veterinary practice where rapid recovery would be expected after bolus administration for short procedures or after infusion for longer procedures. 90 NAL Call. No.: 41.8 AM3A Comparative study of ultrasonography and arteriography of the carotid artery of xylazine-sedated and halothane-anesthetized goats. Lee, S.W.; Hankes, G.H.; Purohit, R.C.; Bartels, J.E.; Cartee, R.E.; Pablo, L.; Conti, J.C. Schaumburg, Ill. : American Veterinary Medical Association; 1990 Jan. American journal of veterinary research v. 51 (1): p. 109-113. ill; 1990 Jan. Includes references. Language: English Descriptors: Goats; Ultrasound; Diagnostic techniques; Blood vessel disorders; Arteries; Neck; Diameter; Blood flow; Xylazine; Halothane Abstract: The carotid artery of clinically normal goats was examined, using duplex ultrasonography and arteriography. The diameter of the carotid artery was measured by use of two-dimensional ultrasonography and Doppler ultrasonography, respectively, before and after xylazine administration. The diameter of the artery was also measured by use of an arteriography technique in halothane-anesthetized goats. There was no significant difference between the mean diameter of the carotid artery measured by ultrasonography in conscious nonsedated goats and that determined by arteriography in goats under halothane anesthesia. On the other hand, ultrasonography of xylazine-sedated goats revealed an increase of carotid artery diameter of 20 to 30%. There was no change in the velocity of blood flow after xylazine administration. 91 NAL Call. No.: 41.8 C81 A comparison of end-tidal halothane concentrations measured at proximal and distal ends of the endotracheal tube in the horse. Matthews, N.S.; Hartsfield, S.M.; Cornick, J.L.; Jacobson, J.D.; Williams, J.D. Ithaca, N.Y. : Cornell Veterinarian, Inc; 1992 Jan. Cornell veterinarian v. 82 (1): p. 21-27; 1992 Jan. Includes references. Language: English Descriptors: Horses; Halothane; Anesthesia; Concentration; Measurement; Sampling 92 NAL Call. No.: SF911.V43 A comparison of injectable anesthetic combinations in horses. Matthews, N.S.; Hartsfield, S.M.; Cornick, J.L.; Williams, J.D.; Beasley, A. Hagerstown, Md. : J.B. Lippincott Company; 1991 Jul. Veterinary surgery v. 20 (4): p. 268-273; 1991 Jul. Includes references. Language: English Descriptors: Horses; Anesthetics; Injectable anesthetics; Xylazine; Drug combinations; Ketamine 93 NAL Call. No.: SF911.V43 A comparison of methods for proximal palmar metacarpal analgesia in horses. Ford, T.S.; Ross, M.W.; Orsini, P.G. Philadelphia, Pa. : J.B. Lippincott Company; 1989 Mar. Veterinary surgery v. 18 (2): p. 146-150. ill; 1989 Mar. Includes references. Language: English Descriptors: Horses; Metacarpus; Carpus; Joints (animal); Anesthesia; Injections; Analgesics; Infiltration 94 NAL Call. No.: SF955.E6 A comparison of responses to analgesia of the navicular bursa and intra-articular analgesia of the distal interphalagneal joint in 59 horses. Dyson, S.J.; Kidd, L. Newmarket : R & W Publications; 1993 Mar. Equine veterinary journal v. 25 (2): p. 93-98; 1993 Mar. Includes references. Language: English Descriptors: Uk; Horses; Lameness; Analgesics; Serous bursa; Joints (animal); Synovial fluid 95 NAL Call. No.: 41.8 V643 Comparison of the effects of two sets of anaesthetic agents and posture on respiratory rate, heart rate, pH, blood gas and acid-base status in the horse. Karimi, A. London : Bailliere Tindall; 1987 Nov. British veterinary journal v. 143 (6): p. 506-512; 1987 Nov. Includes references. Language: English Descriptors: Horses; Anesthetics; Xylazine; Thiopental; Posture; Respiration rate; Heart rate; Ph; Blood; Gases; Acid base equilibrium; Anesthesia 96 NAL Call. No.: SF915.J63 A comparison of the sedative effects of three alpha 2-adrenoceptor agonists (romifidine, detomidine and xylazine) in the horse. England, G.C.W.; Clarke, K.W.; Goossens, L. Oxford : Blackwell Scientific Publications; 1992 Jun. Journal of veterinary pharmacology and therapeutics v. 15 (2): p. 194-201; 1992 Jun. Includes references. Language: English Descriptors: Horses; Xylazine; Agonists; Anesthesia; Dosage; Intravenous injection; Adverse effects 97 NAL Call. No.: SF910.P34A55 1992 Comparison of the thermal and mechanical antiociceptive actions of opioids and alpha 2-adrenoreceptor agonists in sheep. Livingston, A.; Waterman, A.E.; Nolan, A.; Amin, A. New York : Churchill Livingstone; 1992. Animal pain / edited by Charles E. Short, Alan Van Poznak. p. 372-377, 400; 1992. Includes references. Language: English Descriptors: Sheep; Agonists; Opioids; Pain; Testing; Animal experiments; Alpha-adrenergic receptors; Analgesics; Xylazine; Fentanyl; Pethidine; Laboratory tests 98 NAL Call. No.: SF911.V43 A comparison of xylazine-diazepam-ketamine and xylazine-guaifenesin-ketamine in equine anesthesia. Brock, N.; Hildebrand, S.V. Hagerstown, Md. : J.B. Lippincott Company; 1990 Nov. Veterinary surgery v. 19 (6): p. 468-474; 1990 Nov. Includes references. Language: English Descriptors: Horses; Anesthetics; Diazepam; Ketamine; Xylazine; Guaifenesin 99 NAL Call. No.: SF895.P76 Complications associated with alcohol tail-blocks in three horses. Stewart, R.H.; Reed, S.M.; Weisbrode, S.E. Washington, D.C. : Fidia Research Foundation; 1990. Progress in veterinary neurology v. 1 (4): p. 476-480; 1990. Includes references. Language: English Descriptors: Horses; Case reports; Complications; Ethanol; Injection; Tail; Conduction anesthesia 100 NAL Call. No.: SF601.A46 Compressed spectral analysis of the EEG as an indicator of anesthetic quality during anesthesia for orthopedic surgery in the horses. Short, C.E.; Ekstrom, P.M. Lexington, Ky. : The Association; 1993. Proceedings of the annual convention of the American Association of Equine Practitioners. p. 69-80; 1993. Meeting helding on November 29-December 2, 1992, Orlando, Florida. Includes references. Language: English Descriptors: Horses; Anesthesia 101 NAL Call. No.: SF955.E6 A computer-derived protocol to aid in selecting medical versus surgical treatment of horses with abdominal pain. Ducharme, N.G.; Pascoe, P.J.; Lumsden, J.H.; Ducharme, G.R. Newmarket : R & W Publications; 1989 Nov. Equine veterinary journal v. 21 (6): p. 447-450; 1989 Nov. Includes references. Language: English Descriptors: Horses; Abdomen; Pain; Colic; Medical treatment; Surgery; Decision analysis; Computer analysis 102 NAL Call. No.: SF601.C24 A computer-derived protocol using recursive partitioning to aid in estimating prognosis of horses with abdominal pain in referral hospitals. Pascoe, P.J.; Ducharme, N.G.; Ducharme, G.R.; Lumsden, J.H. Ottawa : Canadian Veterinary Medical Association; 1990 Jul. Canadian journal of veterinary research; Revue canadienne de recherche veterinaire v. 54 (3): p. 373-378; 1990 Jul. Includes references. Language: English Descriptors: Horses; Colic; Abdomen; Survival; Estimation; Computer analysis 103 NAL Call. No.: 41.8 R312 Contribution of amino acid transmitters to epileptiform activity and reflex suppression in electrically head stunned sheep. Cook, C.J.; Devine, C.E.; Tavener, A.; Gilbert, K.V. London : British Veterinary Association; 1992 Jan. Research in veterinary science v. 52 (1): p. 48-56; 1992 Jan. Includes references. Language: English Descriptors: Sheep; Stunning; Electrical treatment; Gamma-aminobutyric acid; Amino acids; Receptors; Anesthetics; Reflexes; Convulsions Abstract: In sheep, administration of a combination of zolazepam and tiletamine hydrochloride resulted in a dose dependent reduction in the duration of epileptic activity induced by an electric stun applied to the head. The compound also lengthened the normal period of reflex suppression that occurs after a stun. Excitatory amino acid receptor antagonists (2-amino-7-phosphonoheptanoic and 2-amino-5-phosphonovaleric acids) also reduced the duration of epileptic activity following an electric stun. These drugs did not alter the time of pedal and ear pinch reflex suppression. Administration of bicuculline (a gamma amino-4-butyric acid [GABA] receptor antagonist) reduced the period of stun induced reflex suppression and increased seizure duration. Administration of a GABA receptor agonist, baclofen, increased the duration of reflex suppression. The results suggest that the development of epileptiform-like activity following application of an electric current to the head is dependent upon excitatory amino acid receptors. The reflex suppression that also arises following an electric stun is contributed to by the activation of GABA receptor mechanisms. 104 NAL Call. No.: 41.8 AM3A Correlation between drug and metabolite concentrations in plasma and anesthetic action of ketamine in swine. Loscher, W.; Ganter, M.; Fassbender, C.P. Schaumburg, Ill. : American Veterinary Medical Association; 1990 Mar. American journal of veterinary research v. 51 (3): p. 391-398; 1990 Mar. Includes references. Language: English Descriptors: Pigs; Ketamine; Anesthesia; Blood plasma; Metabolites; Administration; Pharmacokinetics; Pharmacodynamics Abstract: Pharmacokinetic variables and metabolism of IM and IV administered ketamine (15 mg/kg of body weight) were determined in 8 swine (2 adult sows and 6 young pigs). After IM administration, maximal plasma concentration was rapidly reached, but peak concentration varied considerably, although comparison with IV data for the same swine indicated that the drug was almost completely absorbed from the musculature. After IV administration, ketamine kinetics followed a 3-term exponential decrease, indicating rapid initial distribution of the drug to highly vascular tissues including the brain, followed by redistribution into less vascular tissues, and elimination. Redistribution and elimination phases, with similar kinetics as those observed in the IV experiment, also were determined in the IM experiment. After both routes of administration, onset of anesthesia was rapid, and most swine recovered consciousness during the phase of redistribution, indicating that anesthesia is terminated by redistribution of drug from the brain into other tissues, whereas metabolism and excretion are less important for duration of anesthesia induced by ketamine. The time during which the swine resumed a lateral position (sleep time) was positively correlated with plasma ketamine concentration at onset of lateral recumbency, as well as with the area under the plasma concentration-time curve. The minimal plasma ketamine concentration for induction of immobilization was about 2 microgram/ml. In adult sows, ketamine induced profound analgesia, which was not obtained in young pigs; this difference in potency could not be related to pharmacokinetic differences between young and adult swine. With respect to metabolism of ketamine in swine, the major metabolite in plasma was norketamine (metabolite I), whereas a second metabolite (metabolite II) was detected only in low concentrations. Elimination half-life of ketamine was about 2 hours after either IM or IV administration. 105 NAL Call. No.: SF391.P55 Creatine kinase activity in blood plasma and muscles of pigs susceptible and resistant to halothane anaesthesia. Poltarsky, J.; Kolataj, A.; Bulla, J. Wallingford : Commonwealth Agricultural Bureaux; 1989 Dec. Pig news and information v. 10 (4): p. 469-472; 1989 Dec. Includes references. Language: English Descriptors: Pigs; Creatine kinase; Enzyme activity; Blood plasma; Longissimus dorsi; Halothane; Drug resistance; Sex differences 106 NAL Call. No.: 41.8 AM3A Dental dolorimetry for the evaluation of an analgesic agent in the horse. Brunson, D.B.; Collier, M.A.; Scott, E.A.; Majors, L.J. Schaumburg, Ill. : American Veterinary Medical Association; 1987 Jul. American journal of veterinary research v. 48 (7): p. 1082-1086. ill; 1987 Jul. Includes references. Language: English Descriptors: Horses; Analgesics; Teeth; Electrodes; Pain; Measurement 107 NAL Call. No.: 475 J824 Determination of residues of carazolol and a number of tranquillizers in swine kidney by high-performance liquid chromatography with ultraviolet and fluorescence detection. Keukens, H.J.; Aerts, M.M.L. Amsterdam : Elsevier Science Publishers; 1989 Feb17. Journal of chromatography v. 464 (1): p. 149-161; 1989 Feb17. Includes references. Language: English Descriptors: Netherlands; Pigs; Kidneys; Drug residues; Neuroleptics; Determination; Liquid chromatography; Fluorescence; Ultraviolet spectroscopy 108 NAL Call. No.: 41.8 AM3A Determination of sensitivity to metocurine in exercised horses. White, D.A.; Hildebrand, S.V.; Jones, J.H.; Fung, D.L.; Gronert, G.A. Schaumburg, Ill. : American Veterinary Medical Association; 1992 May. American journal of veterinary research v. 53 (5): p. 757-761; 1992 May. Includes references. Language: English Descriptors: Horses; Muscle relaxants; Exercise; Pharmacokinetics; Pharmacodynamics Abstract: On the basis of results in dogs, conditioning exercise may increase sensitivity to nondepolarizing muscle relaxants. Five Thoroughbreds were exercised/conditioned 3 times weekly on a treadmill for 8 months. Increasing maximal rate of O2 consumption verified that the horses were responding to exercise conditioning. Six nonexercised Thoroughbreds served as the control group. Studies were done with horses under general anesthesia by use of halothane during partial paralysis by a brief constant-rate infusion with the muscle relaxant, metocurine iodide. Quantification of degree of paralysis of the hoof twitch (eg, digital extensor) occurred with simultaneous quantification of blood values of metocurine. Pharmacokinetic and pharmacodynamic analyses of the data were done by a nonlinear regression program, using the Hill equation. There were no differences in findings between exercised and nonexercised horses. The mean blood concentration for the 50% paralyzing dose of metocurine was 0.44 +/- 0.11 (SD) micrograms/ml in exercised horses, and 0.58 +/- 0.22 micrograms/ml in nonexercised horses. Despite evidence for a response to conditioning, a significant change in the sensitivity of the neuromuscular junction to metocurine was not found. 109 NAL Call. No.: SF955.E6 Detomidine (Domosedan) in foals: sedative and analgesic effects. Oijala, M.; Katila, T. London : British Equine Veterinary Association; 1988 Sep. Equine veterinary journal v. 20 (5): p. 327-330; 1988 Sep. Includes references. Language: English Descriptors: Foals; Neuroleptics; Analgesics; Drug effects; Heart rate; Body weight 110 NAL Call. No.: SF951.J65 Detomidine hydrochloride versus xylazine plus morphine as sedative and analgesic agents for flank laparotomies and ovary and oviduct removal in standing mares. Jochle, W.; Woods, G.L.; Little, T.V.; Hillman, R.B.; Ball, B.A. Lake Elsinore, Calif. : William E. Jones, DVM; 1991 Jul. Journal of equine veterinary science v. 11 (4): p. 225-228; 1991 Jul. Includes references. Language: English Descriptors: Horses; Mares; Reproductive disorders; Ovariectomy; Oviducts; Surgical operations; Analgesics; Xylazine; Morphine; Laparotomy 111 NAL Call. No.: 41.8 V641 Detomidine-butorphanol sedation in equine clinical practice. Taylor, P.M.; Browning, A.P.; Harris, C.P. London : The Association; 1988 Oct08. The Veterinary record : journal of the British Veterinary Association v. 123 (15): p. 388-390; 1988 Oct08. Includes references. Language: English Descriptors: Horses; Anesthetics; Anesthesia; Drug combinations; Adverse effects 112 NAL Call. No.: 41.8 R312 Development of an enzyme-linked immunosorbent assay for the detection of phenothiazine tranquillisers in horses. Smith, M.L.; Chapman, C.B. London : British Veterinary Association; 1987 May. Research in veterinary science v. 42 (3): p. 415-417; 1987 May. Includes references. Language: English Descriptors: Horses; Phenothiazines; Neuroleptics; Enzyme linked immunosorbent assay; Detection 113 NAL Call. No.: SF955.E6 Dose related effects of the kappa agonist U-50, 488H on behaviour, nociception and autonomic response in the horse. Kamerling, S.; Weckman, T.; Donahoe, J.; Tobin, T. London : British Equine Veterinary Association; 1988 Mar. Equine veterinary journal v. 20 (2): p. 114-118; 1988 Mar. Includes references. Language: English Descriptors: Horses; Analgesics; Dosage effect; Animal behavior; Autonomic nervous system; Neurotropic drugs 114 NAL Call. No.: SF951.J65 Dose selection for detomidine as a sedative and analgesic in horses with colic from controlled and open clinical studies. Jochle, W. Lake Elsinore, Calif. : William E. Jones, DVM; 1990 Jan. Journal of equine veterinary science v. 10 (1): p. 6-11; 1990 Jan. Includes references. Language: English Descriptors: Horses; Colic; Analgesics; Drug effects; Dosage effects; Duration 115 NAL Call. No.: 41.8 AM3A Dynamic baroreflex sensitivity in anesthetized horses, maintained at 1.25 to 1.3 minimal alveolar concentration of halothane. Hellyer, P.W.; Dodam, J.R.; Light, G.S. Schaumburg, Ill. : American Veterinary Medical Association; 1991 Oct. American journal of veterinary research v. 52 (10): p. 1672-1675; 1991 Oct. Includes references. Language: English Descriptors: Horses; Anesthesia; Heart rate; Blood pressure; Reflexes; Xylazine; Ketamine; Halothane; Vasoconstrictor agents Abstract: Dynamic baroreflex sensitivity for increasing arterial pressure (DBSI) was used to quantitatively assess the effects of anesthesia on the heart rate/arterial pressure relationship during rapid (less than or equal to 2 minutes) pressure changes in the horse. Anesthesia was induced with IV administration of xylazine and ketamine and maintained with halothane at a constant end-tidal concentration of 1.1 to 1.2% (1.25 to 1.3 minimal alveolar concentration). Systolic arterial pressure (SAP) was increased a minimum of 30 mm of Hg in response to an IV bolus injection of phenylephrine HCl. Linear regression was used to determine the slope of the R-R interval/SAP relationship. During dynamic increases in SAP, a significant correlation between R-R interval and SAP was observed in 8 of 8 halothane-anesthetized horses. Correlation coefficients between R-R interval and sap were > 0.80 in 5 of 8 horses. Mean (+/- SD) DBSI was 4.8 +/- 3.4 ms/mm of Hg in anesthetized horses. A significant correlation between R-R interval and SAP was observed in only 3 of 6 awake horses during dynamic increases in SAP. Lack of correlation between R-R interval and SAP in 3 of 6 awake horses indicated that rapidly increasing SAP with an IV phenylephrine bolus is a poor method to evaluate baroreceptor-mediated heart rate changes in awake horses. Reflex slowing of heart rate in response to a rising arterial pressure appeared to have been overridden by the effects of excitement. Mean (+/- SD) DBSI (3 horses) was 7.3 +/- 3.3 ms/mm of Hg in awake horses. 116 NAL Call. No.: 41.8 AM3A Effect of body posture on cardiopulmonary function in horses during five hours of constant-dose halothane anesthesia. Steffey, E.P.; Kelley, A.B.; Hodgson, D.S.; Grandy, J.L.; Woliner, M.J.; Willits, N. Schaumburg, Ill. : American Veterinary Medical Association; 1990 Jan. American journal of veterinary research v. 51 (1): p. 11-16; 1990 Jan. Includes references. Language: English Descriptors: Horses; Posture; Halothane; Anesthesia; Cardiovascular system; Respiratory system Abstract: Cardiovascular and respiratory functions were serially characterized in 7 healthy, spontaneously breathing, adult horses (from which food had been withheld) during 5 hours of constant 1.06% alveolar halothane (end-expired halothane concentration of 1.06%; equivalent to 1.2 times the minimal alveolar anesthetic concentration for horses). To enable comparison of temporal results in relation to 2 body postures, horses were studied in lateral recumbency (LR) and dorsal recumbency (DR) on separate occasions. Temporal changes in results of measures of circulation previously reported from this laboratory for horses in LR were confirmed (ie, a time-related increase in systemic arterial blood pressure, cardiac output, stroke volume, and PCV). During DR, systemic arterial blood pressure was initially significantly (P < 0.05) greater and pulmonary artery pressure less than results at comparable periods during LR. Differences ceased to exist with duration of anesthesia. Except for a greater heart rate at hour 5 of DR, no other significant differences in circulation were found between LR and DR. In general, except for PaO2, measures of ventilation did not change with time in either LR or DR. The PaO2 was significantly greater during LR, compared with DR, but the average did not change significantly with time in either body posture. 117 NAL Call. No.: SF910.P34A55 1992 Effect of buffered lidocaine on epidural anesthesia in cattle. Riebold, T.W.; Hawkins, J.K.; Crisman, R.O. New York : Churchill Livingstone; 1992. Animal pain / edited by Charles E. Short, Alan Van Poznak. p. 303-306, 313-315; 1992. Includes references. Language: English Descriptors: Cattle; Anesthesia; Lidocaine; Local anesthetics 118 NAL Call. No.: 41.8 R312 Effect of carbon dioxide stunning on somatosensory evoked potentials in hens. Mohan Raj, A.B.; Gregory, N.G.; Wotton, S.B. London : British Veterinary Association; 1990 Nov. Research in veterinary science v. 49 (3): p. 355-359. ill; 1990 Nov. Includes references. Language: English Descriptors: Fowls; Hens; Stunning; Carbon dioxide; Electroencephalograms; Convulsions; Animal welfare; Anesthesia; Consciousness 119 NAL Call. No.: 41.8 R312 Effect of clenbuterol an arterial oxygen tension in the anaesthetised horse. Gleed, R.D.; Dobson, A. London : British Veterinary Association; 1990 May. Research in veterinary science v. 48 (3): p. 331-337; 1990 May. Includes references. Language: English Descriptors: Horses; Anesthesia; Oxygen; Arteries; Partial pressure; Position; Drugs 120 NAL Call. No.: 41.8 AM3A Effect of halothane, isoflurane, and pentobarbital anesthesia on myocardial irritability in chickens. Greenlees, K.J.; Clutton, R.E.; Larsen, C.T.; Eyre, P. Schaumburg, Ill. : American Veterinary Medical Association; 1990 May. American journal of veterinary research v. 51 (5): p. 757-758; 1990 May. Includes references. Language: English Descriptors: Chickens; Anesthesia; Halothane; Anesthetics; Pentobarbital; Myocardium; Adverse effects Abstract: The relative myocardial irritant properties of halothane, isoflurane, and pentobarbital were evaluated in chickens. Sixteen adult male broiler chickens were randomly assigned to 1 of 3 groups: group-1 chickens were anesthetized with pentobarbital (30 mg/kg, IV), group-2 chickens were anesthetized with halothane (end tidal halothane 1.2%), and group-3 chickens were anesthetized with isoflurane (end tidal isoflurane 2.1%). Birds in any 2 of the 3 treatment groups were tested on any 1 day. Local anesthesia was induced, and blood pressure, heart rate, ECG, and blood gas variables were measured before general anesthesia was induced. Positive-pressure ventilation with an inspired O2 fraction > 0.95 was adjusted to result in an end tidal CO2 concentration that reflected a PaCO2 similar to that obtained prior to anesthesia and ventilation. All measurements were repeated. The threshold for ventricular fibrillation in response to electrical stimulation of the heart was then determined for all birds. Effects of anesthesia on hemodynamic and blood gas variables were similar in all 3 groups. Compared with halothane or pentobarbital, isoflurane anesthesia resulted in a significantly (P < 0.05) lower threshold for electrical fibrillation of the heart. 121 NAL Call. No.: 41.8 V641 Effect of halothane on bronchial calibre of anaesthetised cattle. Watney, G.C.G. London : British Veterinary Association; 1987 Jan03. The Veterinary record v. 120 (1): p. 9-12; 1987 Jan03. Includes references. Language: English Descriptors: Cattle; Halothane; Anesthesia; Bronchi; Volume; Respiration pathways; Xylazine; Diameter 122 NAL Call. No.: 41.8 AM3A Effect of high PaCO2 and time on cerebrospinal fluid and intraocular pressure in halothane-anesthetized horses. Cullen, L.K.; Steffey, E.P.; Bailey, C.S.; Kortz, G.; Da Silva Curiel, J.; Bellhorn, R.W.; Woliner, M.J.; Elliott, A.R.; Jarvis, K.A. Schaumburg, Ill. : American Veterinary Medical Association; 1990 Feb. American journal of veterinary research v. 51 (2): p. 300-304; 1990 Feb. Includes references. Language: English Descriptors: Horses; Anesthesia; Halothane; Hypercapnia; Carbon dioxide; Partial pressure; Timing; Cerebrospinal fluid; Eyes (animal); Internal pressure Abstract: The effects of different arterial carbon dioxide tensions (PaCO2) on cerebrospinal fluid pressure (CSFP) and intraocular pressure (IOP) were studied in 6 male halothaneanesthetized horses positioned in left lateral recumbency. Steady-state anesthetic conditions (1.06% end-tidal halothane concentration) commenced 60 minutes following anesthetic induction with only halothane in oxygen. During atracurium neuromuscular blockade, horses were ventilated, and respiratory rate and peak inspiratory airway pressure were maintained within narrow limits. The CSFP and IOP were measured at 3 different levels of PaCO2 (approx 40, 60, and 80 mm of Hg). The PaCO2 sequence in each horse was determined from a type of switchback design with the initial PaCO2 (period 1), established 30 minutes after the commencement of steady-state anesthesia, being repeated in the middle (period 3) and again at the end (period 5) of the experiment. Measurements taken from the middle 3 periods (2, 3, and 4) would form a Latin square design replicated twice. The interval between each period was approximately 45 minutes. Data from periods 2, 3, and 4 indicated that CSFP (P < 0.05) and mean systemic arterial pressure increased significantly (P < 0.05) with high PaCO2. Mean central venous pressure, heart rate, and IOP did not change significantly during these same conditions. Measurements taken during periods 1, 3, and 5 were compared to assess the time- related responses to anesthesia and showed a significant increase in CSFP, a significant decrease in mean central venous pressure, and a small (but not statistically significant) increase in mean systemic arterial pressure. 123 NAL Call. No.: 41.8 AM3A Effect of hypercapnia on the arrhythmogenic dose of epinephrine in horses anesthetized with guaifenesin, thiamylal sodium, and halothane. Gaynor, J.S.; Bednarski, R.M.; Muir, W.W. III Schaumburg, Ill. : American Veterinary Medical Association; 1993 Feb. American journal of veterinary research v. 54 (2): p. 315-321; 1993 Feb. Includes references. Language: English Descriptors: Horses; Hypercapnia; Epinephrine; Dosage; Anesthesia; Guaifenesin; Halothane; Inhaled anesthetics; Arrhythmia Abstract: The effect of hypercapnia on the arrhythmogenic dose of epinephrine (ADE) was investigated in 14 horses. Anesthesia was induced with guaifenesin and thiamylal sodium and was maintained at an end-tidal halothane concentration between 0.86 and 0.92%. Base-apex ECG, cardiac output, and facial artery blood pressure were measured and recorded. The ADE was determined at normocapnia (arterial partial pressure of carbon dioxide [Pa(CO2)] = 35 to 45 mm of Hg), at hypercapnia (Pa(CO2) = 70 to 80 mm of Hg), and after return to normocapnia. Epinephrine was infused at arithmetically spaced increasing rates (initial rate = 0.25 micrograms/kg of body weight/min) for a maximum of 10 minutes. The ADE was defined as the lowest epinephrine infusion rate, to the nearest 0.25 micrograms/kg/min, at which 4 premature ventricular complexes occurred in a 15-second period. The ADE (mean +/- SD) during hypercapnia (1.04 +/- 0.23 micrograms/kg/min) was significantly (P < 0.05) less than the ADE at normocapnia (1.35 +/- 0.38 micrograms/kg/min), whereas the ADE after return to normocapnia (1.17 +/- 0.22 micrograms/kg/min) was not significantly different from those during normocapnia or hypercapnia. Baseline systolic and diastolic arterial pressures and cardiac output decreased after return to normocapnia. Significant differences were not found in arterial partial pressure of O2 (Pa(O2)) or in base excess during the experiment. Two horses developed ventricular fibrillation and died during normocapnic determinations of ADE. Hypercapnia was associated with an increased risk of developing ventricular arrhythmias in horses anesthetized with guaifenesin, thiamylal sodium, and halothane. 124 NAL Call. No.: SF911.V43 Effect of hypercapnia or xylazine on lateral ventricle and lumbosacral cerebrospinal fluid pressures in pentobarbital-anesthetized horses. Moore, R.M.; Trim, C.M. Hagerstown, Md. : J.B. Lippincott Company; 1993 Mar. Veterinary surgery v. 22 (2): p. 151-158; 1993 Mar. Includes references. Language: English Descriptors: Horses; Cerebrospinal fluid; Anesthesia 125 NAL Call. No.: 41.8 SO8 The effect of lateral and dorsal recumbency on cardiopulmonary function in the anaesthetised horse. Stegmann, G.F.; Littlejohn, A. Pretoria : The Association; 1987 Mar. Journal of the South African Veterinary Association; Tydskrif van die Suid-Afrikaanse Veterinere Vereniging v. 58 (1): p. 21-27; 1987 Mar. Includes references. Language: English Descriptors: Horses; Anesthesia; Position; Body weight; Heart output; Ventilation; Physiological functions; Heart; Lungs 126 NAL Call. No.: 41.8 V643 The effect of pentobarbitone sodium anaesthesia on plasma LH, cortisol and testosterone in goats. Mohamed, F.H.A.; Cox, J.E. London : Bailliere Tindall; 1987 Nov. British veterinary journal v. 143 (6): p. 513-519; 1987 Nov. Includes references. Language: English Descriptors: Goats; Pentobarbital; Anesthesia; Blood plasma; Lh; Cortisol; Testosterone 127 NAL Call. No.: QL876.B5 The effect of stage of estrous cycle and follicular maturation on ovarian inhibin production in sheep. Campbell, B.K.; McNeilly, A.S.; Mann, G.E.; Baird, D.T. Champaign, Ill. : Society for the Study of Reproduction; 1991 Mar. Biology of reproduction v. 44 (3): p. 483-490; 1991 Mar. Includes references. Language: English Descriptors: Ewes; Ovulation; Graafian follicles; Estrus; Granulosa cells; Cell culture; Cloprostenol; Fsh; Lh; Inhibin; Estradiol; Androstenedione; Testosterone; Hormone secretion Abstract: Twenty-four Scottish Blackface ewes (mean weight 50.0 +/- 0.1 kg with ovulation rate 1.3 +/- 0.1) were randomly divided into 4 groups of 6 animals. Under general anesthesia, following the collection of a timed sample of ovarian venous blood, the ovaries of these animals were collected either on Day 10 of the luteal phase or 12, 24, and 48 h after a luteolytic dose of a prostaglandin (PG) F2 alpha analogue (cloprostenol 100 microgram i.m.) administered on Day 10. All follicles greater than 3 mm were dissected from the ovaries and incubated in Medium 199 (M199) at 37 degrees C for 2 h, following which the granulosa cells were harvested and incubated in triplicate for 24 h in M199 with or without ovine FSH or ovine LH. Plasma and culture media samples were assayed for inhibin, estradiol (E2), androstenedione (A4), and testosterone (T) by specific RIA. After correcting for hematocrit, ovarian secretion rates were calculated from the product of the plasma concentration and flow rate. The rate of ovarian inhibin secretion during the luteal phase was similar from ovaries categorized on the basis of presence of luteal tissue (1.0 +/- 0.3 and 0.9 +/- 0.5 ng/min for CL present and absent, respectively), confirming that the ovine CL does not secrete appreciable amounts of inhibin. Inhibin secretion was higher (p < 0.05) at 12 h after PG-induced luteolysis but not at 24 or 48 h compared to values for luteal phase control ewes. Although ovaries containing large estrogenic follicles (greater than or equal to 4 mm in diameter and classified as estrogenic from in vitro criteria) secreted the most inhibin (55%; p < 0.05), both ovaries containing large nonestrogenic follicles (33%) and small (11%; <4 mm in diameter) follicles secreted appreciable amounts of inhibin. This contrasted strongly with E2 where >80% of the steroid was secreted by large estrogenic follicles. The rate of ovarian inhibin secretion was positively correlated (p < 0.05) with the rate of E2, A4, and T secretion. 128 NAL Call. No.: 421 J828 Effect of the anesthetizing agent triethylamine on western equine encephalomyelitis and St. Louis encephalitis viral titers in mosquitoes (Diptera: Culicidae). Kramer, L.D.; Presser, S.B.; Houk, E.J.; Hardy, J.L. Lanham, Md. : The Entomological Society of America; 1990 Nov. Journal of medical entomology v. 27 (6): p. 1008-1110; 1990 Nov. Includes references. Language: English Descriptors: Aedes dorsalis; Culex tarsalis; Anesthesia; Arboviruses; Disease vectors; Public health; St. louis encephalitis virus; Triethylamine; Western equine encephalitis virus 129 NAL Call. No.: SF915.J63 The effect of the organophosphate trichlorfon on the neuromuscular blocking activity of atracurium in halothane-anesthetized horses. Hildebrand, S.V.; Hill, T.; Holland, M. Oxford : Blackwell Scientific Publications; 1989 Sep. Journal of veterinary pharmacology and therapeutics v. 12 (3): p. 277-282; 1989 Sep. Includes references. Language: English Descriptors: Horses; Trichlorfon; Halothane; Anesthesia; Muscle relaxants 130 NAL Call. No.: 41.8 AM3A Effect of withholding feed on ventilation and the incidence of regurgitation during halothane anesthesia of adult cattle. Blaze, C.A.; LeBlanc, P.H.; Robinson, N.E. Schaumburg, Ill. : American Veterinary Medical Association; 1988 Dec. American journal of veterinary research v. 49 (12): p. 2126-2129; 1988 Dec. Includes references. Language: English Descriptors: Cattle; Halothane; Anesthesia; Restricted feeding; Ventilation; Vomiting; Gases; Lungs Abstract: Six cows were anesthetized for 90 minutes with 1.5 minimal alveolar concentrations of halothane in oxygen, after 48 hours without food and 12 hours without water. On a separate occasion, the cows were allowed access to feed and water up to the time of induction of anesthesia, with the sequence of feeding vs fasting randomized. Every 15 minutes, measurements were made of end-tidal halothane concentration, arterial blood gas tensions, mean arterial blood pressure, heart and respiratory rates, tidal volume, minute volume, airflow rate, and transpulmonary pressure, and calculations were made of dynamic compliance and pulmonary resistance. Any regurgitation was recorded. Hypoventilation was noticed in all cows, but to a greater degree in fed cows. Fed cows became hypoxemic, whereas arterial oxygen tension did not change in nonfed cows. Alveolar-arterial oxygen tension gradient, tidal volume, and minute volume did not change. Arterial pH decreased progressively in all cows. Dynamic compliance also decreased progressively in all cows, and was consistently lower in fed cows. Pulmonary resistance tended to increase in all cows, but the increase was significant only in fed cows at 90 minutes. All fed cows became tympanitic, and 2 cows regurgitated a small volume of fluid at 55 minutes. Three nonfed cows regurgitated larger volumes at times ranging from 8 minutes to 85 minutes. 131 NAL Call. No.: 41.8 AM3A Effect of xylazine on the arrhythmogenic dose of epinephrine in thiamylal/halothane-anesthetized horses. Gaynor, J.S.; Bednarski, R.M.; Muir, W.W. III Schaumburg, Ill. : American Veterinary Medical Association; 1992 Dec. American journal of veterinary research v. 53 (12): p. 2350-2354; 1992 Dec. Includes references. Language: English Descriptors: Horses; Anesthetics; Drug combinations; Drug effects Abstract: The effect of xylazine on the arrhythmogenic dose of epinephrine (ADE) was studied in 9 horses. Anesthesia was induced by administration of guaifenesin (50 mg/kg of body weight, IV) followed by thiamylal (4 to 6 mg/kg, IV) and was maintained at 1 minimal alveolar concentration MAC) of halothane (0.89%). Base apex ECG and facial artery pressure were recorded. Epinephrine was infused in a sequence of arithmetically spaced increasing rates (initial rate 0.25 (Lg/kg/min) for a maximum of 10 minutes. The ADE was defined as the lowest epinephrine infusion rate to the nearest 0.25 microgram/kg/min at which at least 4 premature ventricular depolarizations occurred in a 15-second period. Xylazine (1.1 mg/kg, IV) was administered after the control ADE was determined. Xylazine did not significantly alter the ADE (control, 1.12 +/-0.38 microgram/kg/min; xylazine, 1.21 +/- 0.46 microgram/kg/min). Blood pressure increased transiently for 8 minutes after xylazine administration. Baseline systolic and diastolic arterial pressures and heart rate were not significantly different from control baseline pressures and heart rate 15 minutes after xylazine administration. Blood pressure and heart rate increased significantly during control and xylazine ADE determinations. Significant differences in pH, PaO2, PaCO2, or base excess were not observed between baseline and ADE in the control or xylazine groups. One horse developed atrial fibrillation, and 2 horses developed ventricular fibrillation during ADE determinations. 132 NAL Call. No.: 41.8 AM3A Effects of a highly concentrated hypertonic saline-dextran volume expander on cardiopulmonary function in anesthetized normovolemic horses. Moon, P.F.; Snyder, J.R.; Haskins, S.C.; Perron, P.R.; Kramer, G.C. Schaumburg, Ill. : American Veterinary Medical Association; 1991 Oct. American journal of veterinary research v. 52 (10): p. 1611-1618; 1991 Oct. Includes references. Language: English Descriptors: Horses; Fluid therapy; Saline water; Dextran; Solutions; Anesthesia; Cardiovascular system; Respiratory system; Adverse effects Abstract: Conventional fluid resuscitation is unsatisfactory in a small percentage of equine emergency surgical cases because the large volumes of fluids required cannot be given rapidly enough to adequately stabilize the horse. In anesthetized horses, the volume expansion and cardiopulmonary effects of a small volume of highly concentrated hypertonic saline-dextran solution were evaluated as an alternative initial fluid choice. Seven halothane-anesthetized, laterally recumbent, spontaneously ventilating, normovolemic horses were treated with a 25% NaCl-24% dextran 70 solution (HSD) at a dosage of 1.0 ml/kg of body weight, IV, infused over 10 minutes, and the effects were measured for 120 minutes after infusion. Plasma volume expansion was rapid and significant (from 36.6 +/- 4.6 ml/kg to 44.9 +/- 4.8 ml/kg) and remained significantly expanded for the duration of the experiment. Packed cell volume, total blood hemoglobin, and plasma protein concentrations significantly decreased, confirming rapid and sustained volume expansion with hemodilution. Cardiac index and stroke index immediately increased and remained high for the entire study (from 69.6 +/- 15.3 ml/min/kg to 106.6 +/- 28.4 ml/min/kg, and from 1.88 t 0.49 ml/beat/kg to 2.50 +/- 0.72 ml/beat/kg, respectively). Systemic vascular resistance significantly decreased immediately after HSD infusion and remained decreased for the duration of the study (from 1.41 +/- 0.45 mm of Hg/ml/min/kg to 0.88 t 0.22 mm of Hg/ml/min/kg). Arterial and venous blood oxygen content decreased significantly because of hemodilution, but actual oxygen transport transiently increased at the 10-minute measurement before returning toward baseline. Plasma osmolality and sodium significantly increased and remained high for the entire 120 minutes (from 293 +/- 2 osm/L to 326 +/- 9 mosm/L, and from 142.8 +/- 3.3 mM/L to 159.0 +/- 6.2 mM/L, respectively). Urine output increased in 5 of 7 horses within minutes of HSD infusion, but the mean increase was 133 NAL Call. No.: SF910.P34A55 1992 The effects of alpha 2-adrenoreceptor agonist analgesia on the central nervous system in an equine model. Short, C.E.; Kallfelz, F.A.; Otto, K.; Otto, B.; Wallace, R. New York : Churchill Livingstone; 1992. Animal pain / edited by Charles E. Short, Alan Van Poznak. p. 421-430, 433-434; 1992. Includes references. Language: English Descriptors: Horses; Pain; Models; Alpha-adrenergic receptors; Agonists; Analgesics; Drug effects 134 NAL Call. No.: 41.8 R312 Effects of an infusion of dopamine on the cardiopulmonary effects of Escherichia coli endotoxin in anaesthetised horses. Trim, C.M.; Moore, J.N.; Hardee, M.M.; Hardee, G.E.; Slade, E.A. London : British Veterinary Association; 1991 Jan. Research in veterinary science v. 50 (1): p. 54-63; 1991 Jan. Includes references. Language: English Descriptors: Horses; Endotoxins; Escherichia coli; Dopamine; Halothane; Anesthesia; Cardiovascular system; Toxemia 135 NAL Call. No.: 421 J828 Effects of anesthetization and storage temperature on bluetongue virus recovery from Culicoides variipennis (Diptera: Ceratopogonidae) and sheep blood. Work, T.M.; Sawyer, M.M.; Jessup, D.A.; Washino, R.K.; Osburn, B.I. Lanham, Md. : The Entomological Society of America; 1990 May. Journal of medical entomology v. 27 (3): p. 331-333; 1990 May. Includes references. Language: English Descriptors: Sheep; Cervidae; Infection; Bluetongue virus; Blood; Anesthesia; Field experimentation; Storage; Temperature; Culicoides variipennis; Disease vectors; Light traps 136 NAL Call. No.: SF915.J63 Effects of anti-inflammatory analgesic drugs and muscarinic receptor blocking agents on appetite in the pig. Bowden, H.C.; Sharman, D.F.; Stephens, D.B. Oxford : Blackwell Scientific Publications; 1987 Sep. Journal of veterinary pharmacology and therapeutics v. 10 (3): p. 269-272; 1987 Sep. Includes references. Language: English Descriptors: Pigs; Appetite; Analgesics; Antiinflammatory agents; Pharmacodynamics; Statistical analysis 137 NAL Call. No.: 41.8 AM3A Effects of atracurium administered by continuous intravenous infusion in halothane-anesthetized horses. Hildebrand, S.V.; Hill, T. III Schaumburg, Ill. : American Veterinary Medical Association; 1989 Dec. American journal of veterinary research v. 50 (12): p. 2124-2126; 1989 Dec. Includes references. Language: English Descriptors: Horses; Muscle relaxants; Injections; Halothane; Anesthesia; Adverse effects Abstract: Atracurium (0.4 mg/ml in isotonic NaCl solution) was administered by IV infusion to 7 healthy adult horses for 2 hours. Over the 2-hour period, a 95 to 99% reduction of train-of-four hoof-twitch response was maintained by 0.17 +/- 0.01 mg of atracurium/kg of body weight/h, for a total of 161 +/- 6 mg of atracurium (mean +/- SEM) for horses 1 to 4, 6, and 7. Horse 5, a mare in estrus, required 0.49 mg of atracurium/kg/h to maintain comparable relaxation. Hoof-twitch recovery time from 10 to 75% of baseline strength was 19.8 +/- 2.5 minutes for all horses. The 10 to 75% recovery time for horse 5 was 18 minutes. Recovery time from discontinuation of halothane until standing was 86 +/- 14 minutes (range, 55 to 165 minutes). Horse 5 had a 165-minute recovery. Regarding recovery from anesthesia, 3 recoveries were rated as excellent, 1 recovery good, and 2 recoveries as fair. Horse 5 laid quietly until she stood with 1 strong, smooth effort. 138 NAL Call. No.: 41.8 Am3A Effects of clenbuterol hydrochloride on pulmonary gas exchange and hemodynamics in anesthetized horses. Dodam, J.R.; Moon, R.E.; Olson, N.C.; Exposito, A.J.; Fawcett, T.A.; Huang, Y.C.; Theil, D.R.; Camporesi, E.; Swanson, C.R. Schaumburg, Ill. : American Veterinary Medical Association; 1993 May. American journal of veterinary research v. 54 (5): p. 776-782; 1993 May. Includes references. Language: English Descriptors: Horses; Clenbuterol; Gas exchange; Oxygen; Carbon dioxide; Hemodynamics; Anesthesia Abstract: We evaluated the effects of clenbuterol HCl (0.8 micrograms/kg, of body weight, IV), a beta 2, agonist, on ventilation-perfusion matching and hemodynamic variables in anesthetized (by IV route), laterally recumbent horses. The multiple inert gas elimination technique was used to assess pulmonary gas exchange. Clenbuterol HCl induced a decrease in arterial oxygen tension (from 57.0 +/- 1.8 to 49.3 +/- 1.2 mm of Hg; mean +/- SEM) as a result of increased shunt fraction (from 6.6 +/- 2.1 to 14.4 +/- 3.1%) and ventilation to regions with high ventilation-perfusion ratios. In contrast, no changes in these variables were found in horses given sterile water. In horses given clenbuterol HCl, O2 consumption increased from 2.23 +/- 0.18 to 2.70 +/- 0.14 ml . min-1 . kg-1, and respiratory exchange ratio decreased from 0.80 +/- 0.02 to 0.72 +/- 0.01. Respiratory exchange ratio and O2 consumption were not significantly modified in sterile water-treated (control) horses. Clenbuterol HCl administration was associated with increased cardiac index (from 57.4 +/- 4.0 to 84.2 +/- 6.3 ml . min-1 . kg- 1), decreased total peripheral vascular resistance (from 108.3 +/- 9.3 to 47.6 +/- 2.8 mm of Hg . s . kg . ml-1), and decreased pulmonary vascular resistance (from 31.3 +/- 3.8 to 13.6 +/- 0.7 mm of Hg . s . kg . ml-1). Our findings indicated that clenbuterol HCl may potentiate hypoxemia as a result of increased shunt fraction in horses anesthetized by the IV route, and caused changes in hemodynamic variables that were consistent with its ability to stimulate beta 2-adrenergic receptors. 139 NAL Call. No.: 41.8 V641 Effects of detomidine on equine oesophageal function as studied by contrast radiography. Watson, T.D.G.; Sullivan, M. London : The Association; 1991 Jul27. The Veterinary record : journal of the British Veterinary Association v. 129 (4): p. 67-69; 1991 Jul27. Includes references. Language: English Descriptors: Horses; Analgesics; Esophagus; Deglutition; Transit time; Peristalsis; Grass sickness 140 NAL Call. No.: QD415.A1X4 The effects of general anaesthesia on tocainide clearance in the sheep. Runciman, W.B.; Mather, L.E.; Carapetis, R.J.; Ilsley, A.H.; McLean, C.F. London : Taylor & Francis; 1987 Jul. Xenobiotica v. 17 (7): p. 807-813; 1987 Jul. Includes references. Language: English Descriptors: Sheep; Anesthesia; Anesthetics 141 NAL Call. No.: 41.8 AM3A Effects of general anesthesia on myoelectric activity of the intestine in horses. Lester, G.D.; Bolton, J.R.; Cullen, L.K.; Thurgate, S.M. Schaumburg, Ill. : American Veterinary Medical Association; 1992 Sep. American journal of veterinary research v. 53 (9): p. 1553-1557; 1992 Sep. Includes references. Language: English Descriptors: Horses; Anesthesia; Xylazine; Ketamine; Thiopental; Ileum; Cecum; Colon; Electrical activity; Muscles; Drug effects; Intestinal motility; Halothane; Guaifenesin 142 NAL Call. No.: 41.8 AM3A Effects of halothane and isoflurane on baroreflex sensitivity in horses. Hellyer, P.W.; Bednarski, R.M.; Hubbell, J.A.E.; Muir, W.W. III Schaumburg, Ill. : American Veterinary Medical Association; 1989 Dec. American journal of veterinary research v. 50 (12): p. 2127-2134; 1989 Dec. Includes references. Language: English Descriptors: Horses; Halothane; Anesthetics; Reflexes; Blood pressure Abstract: Baroreflex sensitivity (BS) was used to quantitatively assess the effects of halothane and isoflurane on the heart rate/arterial pressure relationship during steady-state (10 minutes) and dynamic pressure changes in adult horses. Arterial pressure was decreased in response to nitroglycerin or sodium nitroprusside and increased in response to phenylephrine HCl. Mean (+/- SEM) BS in awake horses was 28.9 +/- 2.6 and 13.2 +/- 2.0 ms/mm of Hg during steady-state decreases and increases in systolic arterial pressure (SAP), respectively. Halothane and isoflurane either significantly (P < 0.05) decreased or eliminated BS during steady-state decreases in SAP, with no significant differences detected between anesthetic agents. During steady-state decreases in SAP, significant (P < 0.05) correlation between R-R interval and arterial pressure was not observed for 6 of 10 and 4 of 11 halothane and isoflurane anesthesia periods, respectively. Halothane significantly (P < 0.05) decreased BS during steady-state increases in SAP to 7.9 +/- 0.6 and 6.5 +/- 1.1 ms/mm of Hg during low and high minimal alveolar concentration (MAC) multiples, respectively. Isoflurane decreased BS during steady-state increases in SAP to 9.6 +/- 1.5 and 6.6 +/- 1.1 ms/mm of Hg during low and high MAC anesthesia, respectively, with high MAC of isoflurane decreasing BS significantly (P < 0.05), compared with awake and low MAC values. Plasma catecholamine (epinephrine and norepinephrine) concentrations increased significantly (P < 0.05), compared with baseline values during steady-state vasodilator infusions in halothane- and isoflurane-anesthetized horses. Steady-state infusions of phenylephrine in anesthetized horses resulted in arrhythmia development, with premature atrial and ventricular complexes seen in halothane-anesthetized horses and increased heart rate and atrial premature complexes seen less frequently in isoflurane-anesthetized horses. Dynamic BS was 25.0 +/- 4.5 and 20.1 +/- 2.8 ms/mm of Hg f 143 NAL Call. No.: 41.8 AM3A Effects of halothane anesthesia on the clearance of gentamicin sulfate in horses. Smith, C.M.; Steffey, E.P.; Baggot, J.D.; Dunlop, C.I.; Farver, T.B. Schaumburg, Ill. : American Veterinary Medical Association; 1988 Jan. American journal of veterinary research v. 49 (1): p. 19-22; 1988 Jan. Includes references. Language: English Descriptors: Horses; Halothane; Gentamicin; Renal clearance; Pharmacokinetics; Urine analysis; Models 144 NAL Call. No.: 41.9 AM37 The effects of intra-articular anesthesia on soft tissue- and bone-phase scintigraphy in the horse. Trout, D.R.; Hornof, W.J.; Fisher, P.E. Raleigh, N.C. : American College of Veterinary Radiology; 1991 Sep. Veterinary radiology v. 32 (5): p. 251-255; 1991 Sep. Includes references. Language: English Descriptors: Horses; Scintigraphy; Local anesthesia 145 NAL Call. No.: 41.8 AM3A Effects of ketamine infusion on halothane minimal alveolar concentration in horses. Muir, W.W. III; Sams, R. Schaumburg, Ill. : American Veterinary Medical Association; 1992 Oct. American journal of veterinary research v. 53 (10): p. 1802-1806; 1992 Oct. Includes references. Language: English Descriptors: Horses; Ketamine; Halothane; Requirements; Dosage effects; Hemodynamics; Anesthesia Abstract: Eight adult horses were used in a study to determine ketamine's ability to reduce halothane requirement. To obtain steady-state plasma concentrations of 0.5, 1.0, 2.0, 4.0, and 8.0 microg/ml, loading doses and constant infusions for ketamine were calculated for each horse on the basis of data from other studies in which the pharmacokinetic properties of ketamine were investigated. Blood samples for determination of plasma ketamine concentrations were collected periodically during each experiment. Plasma ketamine concentrations were determined by capillary gas chromatography/mass spectrometry under electron-impact ionization conditions, using lidocaine as the internal standard. Halothane minimal alveolar concentration (MAC; concentration at which half the horses moved in response to an electrical stimulus) and plasma ketamine concentration were determined after steady-state concentrations of each ketamine infusion had been reached. Plasma ketamine concentrations > 1.0 microg/ml decreased halothane MAC. The degree of MAC reduction was correlated directly with the square root of the plasma ketamine concentration, reaching a maximum of 37% reduction at a plasma ketamine concentration of 10.8 +/- 2.7 microg/ml. Heart rate, mean arterial blood pressure, and the rate of increase of right ventricular pressure did not change with increasing plasma ketamine concentration and halothane MAC reduction. Cardiac output increased significantly during ketamine infusions and halothane MAC reduction. Our findings suggest that plasma ketamine concentrations > 1.0 microm/ml reduce halothane MAC and produce beneficial hemodynamic effects. 146 NAL Call. No.: 41.8 AM3A Effects of ketamine, xylazine, and a combination of ketamine and xylazine in Pekin ducks. Ludders, J.W.; Rode, J.; Mitchell, G.S.; Nordheim, E.V. Schaumburg, Ill. : American Veterinary Medical Association; 1989 Feb. American journal of veterinary research v. 50 (2): p. 245-249; 1989 Feb. Includes references. Language: English Descriptors: Ducks; Ketamine; Xylazine; Drug combinations; Anesthesia; Adverse effects; Cardiovascular system; Respiratory system Abstract: Effects of ketamine, xylazine, and a combination of ketamine and xylazine were studied in 12 male Pekin ducks (7 to 12 weeks old; mean [+/- SD] body weight, 3.1 +/- 0.3 kg). After venous and arterial catheterization and fixation of a temperature probe in the cloaca, each awake duck was confined, but not restrained, in an open box in a dimly lit room. Blood pressure and lead-II ECG were recorded. Three arterial blood samples were collected every 15 minutes over a 45-minute period (control period) and were analyzed for pHa, Paco2 and Pao2. After the control period, each duck was assigned at random to 1 of 3 drug groups: (1) ketamine (KET; 20 mg/kg of body weight, IV), (2) xylazine (XYL; 1 mg/kg, IV), and (3) KET + XYL (KET 20 mg/kg and XYL, 1 mg/kg; IV). Measurements were made at 1, 5, 10, 15, 30, 45, 60, and 90 minutes after drug administration. All ducks survived the drug study. Cloacal temperature was significantly (P less than or equal to 0.05) increased above control cloacal temperature at 90 minutes after the administration of ketamine, and from 10 through 90 minutes after administration of ketamine plus xylazine. In ducks of the KET group, pHa, Paco2, and Pao2, remained unchanged after administration of the drug. In ducks of the XYL group, pHa and Pao2 decreased significantly (P less than or equal to 0.05) from control values for all time points up to and including 15 minutes after drug administration. In ducks of the KET + XYL group, pHa and Pa02 were significantly (P less than or equal to 0.05) decreased at all time points up to and including 45 and 15 minutes, respectively, after administration of the drugs. In ducks of the XYL group, Paco2 increased significantly (P less than 0.05) during the first 15 minutes after drug administration, and for 45 minutes after administration of KET + XYL. Results indicated that ketamine when given alone to ducks, was not associated with pulmonary depression. There was drug-associated respiratory depression after IV admini 147 NAL Call. No.: 41.8 R312 Effects of local anaesthesia and intravenous naloxone on the changes in behaviour and plasma concentrations of cortisol produced by castration and tail docking with tight rubber rings in young lambs. Wood, G.N.; Molony, V.; Fleetwood-Walker, S.M.; Hodgson, J.C.; Mellor, D.J. London : British Veterinary Association; 1991 Sep. Research in veterinary science v. 51 (2): p. 193-199; 1991 Sep. Includes references. Language: English Descriptors: Lambs; Castration; Docking; Hydrocortisone; Lidocaine; Naloxone; Behavior change; Blood plasma; Pain; Local anesthesia Abstract: The reliability of some behavioural and physiological indices used for the recognition and assessment of acute pain in lambs after castration and tail docking has been examined. Changes in the indices were measured after blocking neural activity with local anaesthetic (lignocaine) and after an opioid antagonist (naloxone) was administered. Six lambs, aged less than one week, were allocated randomly to each of six treatments. (i) control handling and blood sampling; (ii) castration plus tail docking with tight rubber rings; (iii) local anaesthesia; (iv) local anaesthesia followed by castration and tail docking; (v) intravenous naloxone only (0.2 mg kg-1); and (vi) intravenous naloxone followed by castration and tail docking. Local anaesthesia eliminated the behavioural and plasma cortisol changes which usually follow castration and tail docking. Naloxone had a limited effect on the increase in cortisol but altered the behaviour. The results support the view that such indices are useful for assessment of the response to acute pain and that, although endogenous opioids do reduce pain in young lambs after castration and tail docking, the effect is small. 148 NAL Call. No.: SF951.E62 Effects of perioperative administration of nonsteroidal antiinflammatory drugs on anesthetic recovery in the horse. Brouwer, G.J. Santa Barbara, Calif. : Veterinary Practice Pub. Co; 1987 Sep. Equine practice v. 9 (8): p. 22, 24-25; 1987 Sep. Includes references. Language: English Descriptors: Horses; Anesthesia; Surgery; Antiinflammatory agents 149 NAL Call. No.: 41.9 AM37 The effects of regional perineural anesthesia on soft tissue and bone phase scintigraphy in the horse. Trout, D.R.; Hornof, W.J.; Liskey, C.C.; Fisher, P.E. Raleigh, N.C. : American College of Veterinary Radiology; 1991 May. Veterinary radiology v. 32 (3): p. 140-144; 1991 May. Includes references. Language: English Descriptors: Horses; Scintigraphy; Local anesthesia; Feet 150 NAL Call. No.: QP251.A1T5 Effects of short-term stress, xylazine tranquilization and anesthetization with xylazine plus ketamine on plasma concentrations of cortisol, luteinizing hormone, follicle stimulating hormone and prolactin in ovariectomized pony mares. Thompson, D.L.; Garza, F. Jr; Mitchell, P.S.; St George, R.L. Stoneham, Mass. : Butterworth Publishers; 1988 Nov. Theriogenology v. 30 (5): p. 937-946; 1988 Nov. Includes references. Language: English Descriptors: Mares; Ovariectomized females; Prolactin; Lh; Fsh; Cortisol; Hormone secretion; Anesthesia; Xylazine; Neuroleptics; Stress; Ketamine 151 NAL Call. No.: 410.9 P94 Effects of surgical pentobarbital anesthesia on blood pressure, heart rate, and arterial blood pH and gas tension in turkeys. Lee, J.C.; McGrath, C.J.; Leighton, A.T. Jr; Wilson, M.H. Cordova, Tenn. : American Association for Laboratory Animal Science; 1988 Apr. Laboratory animal science v. 38 (2): p. 208-210; 1988 Apr. Includes references. Language: English Descriptors: Turkeys; Anesthesia; Pentobarbital; Blood pressure; Heart rate; Blood ph; Gases; Tension 152 NAL Call. No.: 41.8 AM3A Effects of xylazine butorphanol on cecal arterial blood flow, cecal mechanical activity, and systemic hemodynamics in horses. Rutkowski, J.A.; Eades, S.C.; Moore, J.N. Schaumburg, Ill. : American Veterinary Medical Association; 1991 Jul. American journal of veterinary research v. 52 (7): p. 1153-1158; 1991 Jul. Includes references. Language: English Descriptors: Horses; Xylazine; Cecum; Blood flow; Blood pressure; Cardiac output; Heart rate; Motility; Hemodynamics; Analgesics Abstract: A chronic model with an ultrasonic transit time blood flow probe and strain gauge force transducers implanted on the cecum was used to evaluate cecal mechanical activity and cecal arterial blood flow in 4 conscious adult horses. Intravenous administration of xylazine (1.1 mg/kg of body weight) significantly decreased heart rate and cardiac output, but significantly increased diastolic pulmonary arterial pressure, mean pulmonary arterial pressure, carotid arterial pressure, and central venous pressure. Lateral cecal arterial blood flow after xylazine administration was decreased substantially more than was cardiac output, suggesting that xylazine caused constriction of the cecal vasculature. This effect of xylazine may have resulted from either a direct effect of xylazine on the cecal vasculature or from reflex vasoconstriction attributable to reduced cardiac output. Intravenous administration of butorphanol tartrate (0.1 mg/kg) did not significantly alter the hemodynamic responses to xylazine. Cecal mechanical activity, as measured by the motility index, was decreased for 120 minutes after administration of xylazine and for 150 minutes after administration of xylazine/butorphanol. 153 NAL Call. No.: 41.8 AM3A Effects of xylazine on equine intestinal vascular resistance, motility, compliance, and oxygen consumption. Stick, J.A.; Chou, C.C.; Derksen, F.J.; Arden, W.A. Schaumburg, Ill. : American Veterinary Medical Association; 1987 Feb. American journal of veterinary research v. 48 (2): p. 198-203. ill; 1987 Feb. Includes references. Language: English Descriptors: Horses; Xylazine; Intestine motility; Resistance; Oxygen consumption; Anesthesia 154 NAL Call. No.: 41.8 AM3 Effects to tolazoline and yohimbine on xylazine-induced central nervous system depression, bradycardia, and tachypnea in sheep. Hsu, W.H.; Schaffer, D.D.; Hanson, C.E. Schaumburg, Ill. : The Association; 1987 Feb15. Journal of the American Veterinary Medical Association v. 190 (4): p. 423-426; 1987 Feb15. Includes references. Language: English Descriptors: Sheep; Anesthesia; Xylazine; Anesthetics; Central nervous system; Respiration; Heart rate 155 NAL Call. No.: SF911.V43 Electroencephalographic power spectrum analysis as a monitor of anesthetic depth in horses. Otto, K.; Short, C.E. Hagerstown, Md. : J.B. Lippincott Company; 1991 Sep. Veterinary surgery v. 20 (5): p. 362-371; 1991 Sep. Includes references. Language: English Descriptors: Horses; Anesthesia; Electroencephalograms; Spectral analysis; Brain 156 NAL Call. No.: SF911.V43 Electroencephalography of detomidine-ketamine-halothane and detomidine-ketamine-isoflurane anesthetized horses during orthopedic surgery--a comparison. Ekstrom, P.M.; Short, C.E.; Geimer, T.R. Hagerstown, Md. : J.B. Lippincott Company; 1993 Sep. Veterinary surgery v. 22 (5): p. 414-418; 1993 Sep. Includes references. Language: English Descriptors: Horses; Electroencephalograms; Anesthesia 157 NAL Call. No.: 41.8 V641 Electro-immobilisation of sheep may not reduce the aversiveness of a painful treatment. Rushen, J.; Congdon, P. London : British Veterinary Association; 1987 Jan10. The Veterinary record v. 120 (2): p. 37-38; 1987 Jan10. Includes references. Language: English Descriptors: Sheep; Immobilization; Electrical treatment; Pain 158 NAL Call. No.: 41.8 R312 Electromyography of some respiratory muscles in the horse. Hall, L.W.; Aziz, H.A.; Groenendyk, J.; Keates, H.; Rex, M.A.E. London : British Veterinary Association; 1991 May. Research in veterinary science v. 50 (3): p. 328-333; 1991 May. Includes references. Language: English Descriptors: Horses; Muscles; Diaphragm; Abdomen; Electromyography; Anesthesia Abstract: To investigate activity in respiratory muscles, insulated wire electrodes were used to record electromyographic activity in the costal diaphragm and in the intercostal, serratus ventralis, internal abdominal oblique, transversalis and rectus abdominis muscles in conscious horses and in the same animals when anaesthetised. Electromyographic activity was related to respiratory phases as recorded by a stethograph around the chest wall. The costal diaphragm showed tonic and inspiratory activity in both conscious and anaesthetised animals. The principal muscle actively involved in expiration was the transversalis muscle. Intercostal muscle activity, and any increased activity in the second part of either inspiration or expiration recorded in the conscious animal, was absent under anaesthesia. The very marked tonic activity found in the serratus ventralis muscle in standing horses disappeared during anaesthesia. It was concluded that any stabilisation of the chest wall contributed by activity in the serratus ventralis and intercostal muscles in conscious, standing horses is greatly reduced during anaesthesia. 159 NAL Call. No.: SF915.J63 Eltenac, a new anti-inflammatory and analgesic drug for horses: clinical aspects. Prugner, W.; Huber, R.; Luhmann, R. Oxford : Blackwell Sci