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The following videos are selected presentations focusing on 3Rs (replacement, reduction, and refinement of animal use) methods to improve laboratory animal welfare while maintaining or improving scientific results. Topics include microphysiological systems, animal/organ sharing, optimizing breeding, research design and statistical strategies among other topics. The 2024 Symposium playlist on Practical Approaches to Each of the 3Rs can be viewed on YouTube or as individual videos below.
The 2024 Symposium was held virtually and co-hosted by:
- USDA, NAL, Animal Welfare Information Center (AWIC)
- NIH Office of Laboratory Animal Welfare (OLAW)
- Johns Hopkins Department of Molecular and Comparative Pathobiology
- Johns Hopkins Center for Alternatives to Animal Testing (CAAT)
Optimizing Breeding and Management of Genetically Modified Animal Models
Speaker: Zachary Freeman, University of Michigan
An Effective Approach to Animal Tissue Sharing in Research
Speaker: Magdalena Czubala, Cardiff University
Think Big, Not Small, to Reduce N Overall
Speaker: Reid D. Landes, University of Arkansas
The Three Pillars of Organs-On-A-Chip Technologies: Where to Innovate?
Speaker: Vadim Jucaud, Terasaki Institute for Biomedical Innovation
3D Fluid-Dynamic Ovarian Cancer Model Resembling Systemic Drug Administration for Efficacy Assay
Speaker: Silvia Scaglione, National Research Council, React4life
Cecal Slurry as an Alternative Model to Cecal Ligation and Puncture for the Study of Sepsis-Induced Cardiovascular Dysfunction
Speaker: Gabrielle Delfrate, Universidade Federal de Santa Catarina
Integrating Immune-Based Microphysiological Assays with Omic and Clinical Data into an In Silico Model to Identify and Screen Novel Therapeutics for Treating Inflammatory Disease
Speaker: Mohammad Kiani, Temple University
Home Cage-Based Phenotyping in Rodents: Innovation, Standardization, Reproducibility, and Translational Improvement
Speaker: Stefano Gaburro, Digilab, Techniplast
Addressing the Animal Research Controversy
Speaker: Lisa Levin, Coridea LLC
The OBSERVE Guidelines for the Refinement of Rodent Cancer Models
Speaker: Stéphanie De Vleeschauwer, Laboratory Animal Center KU Leuven
3D Bioprinted Primary Human Breast Cancer Tissues
Speaker: Ibrahim Ozbolat, Penn State University
Light Cycles and Research Animal Welfare
Speaker: Robert Dauchy, Tulane University School of Medicine
A Good Death: Refining Methods of Euthanasia
Speaker: Jasmine Clarkson, Newcastle University
RE-Place: A Unique Project Collecting Expertise on New Approach Methodologies
Speaker: Maude Everaert, RE-Place
Pilot Studies: An Under-Used 3Rs Tool
Speaker: Penny Reynolds, University of Florida
Using Mice to Model Human Disease
Speaker: Elizabeth Repasky, Roswell Park Comprehensive Cancer Center
These presentations are being hosted by the Animal Welfare Information Center, a service of The National Agricultural Library. Staff did not edit or otherwise modify the original materials. The views expressed in the presentations do not necessarily reflect the policies of the National Agricultural Library or the United States Department of Agriculture.