The National Institute of Environmental Health Sciences (NIEHS) is offering Small Business Innovation Research (SBIR) grants to develop novel in vitro systems using cells from experimental animal models typically used for toxicology testing. The intent is that these systems will replicate biological responses within the corresponding animal tissues or organs. When developed and validated, these systems will (1) provide information needed to predict toxicity of chemical and drug candidates, (2) enable comparisons with existing in vivo animal toxicity data, (3) serve as newer assays for toxicology testing, and (4) have the potential for reducing the numbers of animals used in toxicology testing.
These grants of up to $150,000 for Phase I awards and up to $1 million for Phase II awards are only available to U.S. small businesses. Letters of intent to apply for these grants are due December 12, with an application due date of January 12, 2018. The funding announcement for this opportunity is available at https://grants.nih.gov/grants/guide/rfa-files/RFA-TR-18-001.html; more information about NIEHS SBIR grants is available at https://www.niehs.nih.gov/funding/grants/mechanisms/sbir/index.cfm.