Pharmacology and Toxicology

DHHS. National Library of Medicine.

The intent of the bibliography is to assist in identifying methods and procedures helpful in supporting the development, testing, application, and validation of alternatives to the use of vertebrates in biomedical research and toxicology testing. Contents are a subset of MEDLINE records.

Years of coverage: 1980 - present
Content types: journal articles
Access: free online

Federal Institute for Risk Assessment (BfR). Centre for Documentation and Evaluation of Alternatives to Animal Experiments (ZEBET).

ZEBET is scientific institution that aims to bring about the replacement of legally prescribed animal experiments with alternative test methods, to reduce the number of test animals to the absolutely necessary level and to alleviate the pain and suffering of animals used in experiments. ZEBET is responsible for documenting alternatives to animal experiment, for assessing them, for recommending their use both nationally and internationally. They are also involved in research of their own to develop alternative methods.

Years of coverage: 2002 - present
Content types: books; journals; monographs; laws; regulations; directions; guidelines; recommendations; pharmacopoeia; dissertations; congress papers; proceedings of meetings; conferences; symposia
Access: free online

European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM).

The EURL ECVAM is an international center for coordinating the validation of alternative methods, providing advice on theoretical and practical aspects of the validation of new tests, and the current state of validation of alternative methods for use in toxicology and the biosciences in general. DB-ALM (formerly called the Scientific Information Service -SIS) is a database on advanced alternative methods in biomedical sciences, providing factual and evaluated (therefore ready-to-use) informative data sheets on advanced non-animal test development and validation for toxicology assessments.

Access: free online

United States Environmental Protection Agency.

The ECOTOXicology database (ECOTOX) is a source for locating single chemical toxicity data for aquatic life, terrestrial plants and wildlife.

Years of coverage: 1971 - present
Type of content: data
Access: free online

Elsevier.

This is a comprehensive international database on pharmacological and biomedical literature, similar to Medline. It contains drug-related and clinical literature, with a particular focus on comprehensive indexing of adverse drug reactions; emphasis on Evidence Based Medicine (EBM) indexing including systematic reviews, and coverage and indexing of journals and articles relevant to the development and use of medical devices.

Years of coverage: 1947 - present
Content types: journal articles; conference proceedings; symposia; meetings; books
Access: fee based

United States Environmental Protection Agency.

The Science Inventory is a searchable database of research products primarily from EPA's Office of Research and Development. Science Inventory records provide descriptions of the product, contact information, and links to available printed material or websites.

Access: free online

DHHS. NIH. National Toxicology Program.

ICE provides high-quality curated data and appropriate tools to support development and evaluation of new, revised, and alternative methods

Content types: data
Access: free online 

Thompson Reuters.

This database covers international literature in applied pharmacology, including drug use and development. Each record is accompanied by an English-language abstract.

Years of coverage: 1964 - present
Content types: journal articles
Access: fee based

USDA. APHIS. National Wildlife Research Center

The NWRC Chemical Effects Database is a searchable database that contains bioassay records and data for chemicals analyzed and evaluated for repellency, toxicity, reproductive inhibition, and immobilization. Studies were conducted from 1943 to 1987 by the U.S. Department of Agriculture's National Wildlife Research Center (NWRC), its predecessors, and by the U.S. Geological Survey's Patuxent Wildlife Research Center (PWRC) (formerly part of the U.S. Fish and Wildlife Service). Includes full-text references.

Years of coverage: 1943-1987
Content types: data
Access: free online

ProQuest.

Bibliographic information from 22 key U.S. and international pharmaceutical, health care, biotechnology, medical device, and cosmetic industry newsletters.

Years of coverage: 1973 - present
Content types: newsletters
Access: fee based

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