Pharmacology and Toxicology

USDA. APHIS. National Wildlife Research Center

The NWRC Chemical Effects Database is a searchable database that contains bioassay records and data for chemicals analyzed and evaluated for repellency, toxicity, reproductive inhibition, and immobilization. Studies were conducted from 1943 to 1987 by the U.S. Department of Agriculture's National Wildlife Research Center (NWRC), its predecessors, and by the U.S. Geological Survey's Patuxent Wildlife Research Center (PWRC) (formerly part of the U.S. Fish and Wildlife Service). Includes full-text references.

Years of coverage: 1943-1987
Content types: data
Access: free online

Thompson Reuters.

This database covers international literature in applied pharmacology, including drug use and development. Each record is accompanied by an English-language abstract.

Years of coverage: 1964 - present
Content types: journal articles
Access: fee based


Scopus is a large abstract and citation database of research literature and quality web sources. Coverage includes scientific, technical, medical and social sciences literature with complete coverage of Medline, along with more life sciences and health related citations and web sites.

Years of coverage: 1823 - present
Content types: journal articles; trade publications; books
Access: fee based

European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM).

The EURL ECVAM is an international center for coordinating the validation of alternative methods, providing advice on theoretical and practical aspects of the validation of new tests, and the current state of validation of alternative methods for use in toxicology and the biosciences in general. DB-ALM (formerly called the Scientific Information Service -SIS) is a database on advanced alternative methods in biomedical sciences, providing factual and evaluated (therefore ready-to-use) informative data sheets on advanced non-animal test development and validation for toxicology assessments.

Access: free online

DHHS. National Library of Medicine.

The intent of the bibliography is to assist in identifying methods and procedures helpful in supporting the development, testing, application, and validation of alternatives to the use of vertebrates in biomedical research and toxicology testing. Contents are a subset of MEDLINE records.

Years of coverage: 1980 - present
Content types: journal articles
Access: free online

A comprehensive database of toxicity information for over 150,000 chemical substances including: prescription and non-prescription drugs, food additives, pesticides, fungicides, herbicides, solvents, diluents, chemical wastes, reaction products of chemical waste, and substances used in both industrial and household situations. Reports of the toxic effects of each compound are cited. In addition to toxic effects and general toxicology reviews, data on skin and/or eye irritation, mutation, reproductive consequences and tumorigenicity are provided. Federal standards and regulations and NIOSH recommended exposure limits are included. It is also part of another database called Biovia Toxicity

Years of coverage: 1971 - present
Content types: reports, data, journal articles
Access: fee based