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Item ID Number

D

Erickson, L.C.

Corporate Author
RepOrt/ArtldO Tltte Herbicides (How Poisonous Are They?)

Journal/Book Title
Year

1967

Month/Day

September

Color

D

Number of Images

4

Doscrlpton Notes

Thursday, November 01, 2001

Page 2546 of 3007

�NUMBER 58

CUEEBNT INFORMATION SEEIES

SEPTEMBER 1967

1

33 --.

HERBICIDES

u

&gt;

(How poisonous are they?)

L C. Erickson

R. E. Higgins

C. I. Seely

Agronomist"

Extension Agronomist

Agronomist

The answer is always a relative one — "Compared to what?"
Most herbicides are relatively non-toxic to
man. A few, however, are quite poisonous. All
must be handled with utmost care. Note that
"caution with" — and "fear of" are not equivalent statements. Almost every imaginable substance can be poisonous and American agriculture uses millions of pounds of herbicides annually. America also produces the purest, highest
quality food on earth.
To obtain information on toxicity, the herbicides are tested on various animals: mice, rats,
etc. Few have been tested on humans.
Therefore, the toxicity ratings given hereafter
are the known effects on animals and it is probable that the herbicide will produce similar effects on man. Certain individuals may be allergic
to a bland chemical or its carrier whereas other
individuals may be resistant to some of the more
toxic substances.
It should be mentioned that the LD-50 values
(lethal to 50% of the animals tested) are for

a single dosage. Repeated treatments over long
periods may give different results.
Any herbicide ingested in sufficient quantities
can cause ill effects. Some are readily absorbed
through the skin, others affect the eyes, and some
produce disagreeable results when inhaled.
When using any herbicide always:
1. Read the entire label carefully. Be sure to
study and follow the precautions on the label.
2. Avoid spilling the material on your skin
or clothing. It is best to wear rubber footwear,
long sleeves, rubber gloves and other designated
protective clothing. In case of spillage, wash the
contacted areas immediately with soap and water.
3. Do not smoke while using chemicals.
4. After using chemicals, change clothes and
wash thoroughly. This is especially important if
the chemical has been spilled on clothing or skin.
The following table gives the common name
and one or more trade names of about 100 herbicides that have extensive to minor usage in this
state.
Numerical toxicity rating is based on a modification of the classification of pesticides in the

Agricultural Extension Service

Agricultural Experiment Station

College of Agriculture

University of Idaho

Introduction

�Toxicity Response of Small Animals of Indicated Herbicide Dosages

Common Name or
Designation

LD-50
Mg./KB.

Some Common Trade
Names

Amitrole-T
Aromatic solvents
Aspirin
Atrazine

Aqualin
Ametryn
Ammate
Amiben, Vegiben
Amino Triazole
Weedazol
Amitrol-T, Cytrol
Various brands
(For Comparison)
Atrazine

Bandane
Barban
Benefin
Bensulide
Bo rate
Bromacil
Bromoxynil

Bandane
Carbyne
Balan
Betasan, Pre-San
Borax, Borascue
Hyvar X
Buctril, Brominil

Cacodylic acid
Calcium arsenate
Calcium cyanamide
CDAA
CDEC
Chloroxuron
CIPC
CMA
Copper sulfate
Cypromid

Ansar560,120
Various brands
Aero-Cyanamide
Randox
Vegadex
Tenoran
Chloro-IPC
Super-Dal-E-Rad
Various brands
Clobber

Dalapon
—
DCPA
Diallate
Dicamba
Dichlobenil
Dichlone

Dowpon
Daxtron
Dacthal
Avadex
Banvel D
Casoron
Phygon

Diphenamid
Diquat

Dymid, Enide
Diquat

2,200

Diuron
DMPA
DMTT
DNBP
DNBP (amine)
DSMA

Karmex
Zytron
Mylone
Sinox, Dow General
Premerge, Sinox PE
Sodar, Ansar, AAethar

3,400
1,000

Acrolein
Ametryn
AMS
Amiben
Amitrole

Ingested Dermal
Toxicity Response
Rating* Rating**

4
6

2
5
5
—
5

4-5
3
4
4

—
—
—
5

4
4
4
4
4
5
3

4

46

2

1,110

4

1,600
3,500
15,000

4

5,000
—
750

3,080
540

1,350
10,000
770

2,500
5,200
260

1,000
35

1,400
700
850

2,700
5,000
440
300
900

9,300
80-100
3,000
395

1,040
2,460
1,380
400

500
30
40
600

4
2
4
4
4
4
5
3
3
4

5
4
—
2
3

4
3
4
3
4
4
4

4
5
5
3
4
5
3

4
3

4
3

4
4
4
2
2
4

4
4
4
1
1
3

* The toxlcity ratings in the table have the following relative meanings when taken internally:
Class
Toxicity
LD 50
activity
rating
(Mg./Ke.)
Extremely toxic
less than 5
1
Very toxic
5 to 49
2
Moderately toxie
50 to 499
3
Slightly toxic
500 to 4,999
4
5
6

Almost Nontoxic
Nontoxic

5,000 to 14,999
15,000 and above

** Dermal response ratings have the following relative meanings:
1 Absorbed and poisonous
2 Causes burns and blisters
3. Moderately Irritating
4. Mildly Irritating
5. Nonirritating
•«» May not be sole or primarily manufacturer(s).

3
4
4
5
—

5
5
—

Mfg.
Company***

Shell
Geigy
DuPont
Amchem
American
Cyanamid
Amchem

Geigy
Velsicol
Gulf
Lilly
Stauffer
U.S. Borax
DuPont
Amchem
Chipman
Ansul
Chipman, etc.
Am. Cyanamid
Monsanto
Monsanto
C.I.B.A.
PPG
Ansul
Gulf
Dow
Dow
Dia. Alkali
Monsanto
Velsicol
T. Hayward
Naugatuck-div.
U.S. Rubber
Elanco
Chevron
Ortho Div.
DuPont
Dow
U. Carbide
Dow-Niagra
Dow-Niagra
Ansul-Niagra

Probable lethal dose
for 150-lb. man
A taste (less than 1
drops)
7 drops to 1 teaspoonful
1 teaspoon to 1 ounce
1 ounce to 1 pint (1
pound)
1 pint to 1 quart
more than 1 quart

�Toxicity Response of Small Animals to Indicated Herbicide Dosages

Common Name or
Designation

Some Common Trade
Namei

LD-50
Mfl./K9.

Ingetled Dermal
Toxicity Response
Rating* Rating**

Endothal
EPIC
Erbon

Endothal, Aquathol
Eptam
Baron, Novon

35
1,630
1,000

2

3

4
4

4
3

Fenac
Fenuron
Fenuron + TCA
Fluometuron

Fenac
Dybar
Urab
Cotoran

3,000
6,400
4,000
8,900

4
5
4
5

_

_

4
—
5

Mfg.

Company**

Pennsalt
Stauffer
Dow
Amchem
DuPont
CIBA

Gasoline
GPS 1393

Various brands
Ramrod

1,200

3
4

_

1

Monsanto

HCA (hexachloroacetone)

HCA Weed Killer

1,290

4

—

Allied
Gen. Div.

loxynil
IPC
Isocil

Bentrol
Propham
Hyvar

305
3,000
3,250

3
4
4

__
—
—

Amchem
PPG
DuPont

Kerosene
KOCN

Various brands
Various brands

—
85

2-3
3

—
5

Am. Cyanamid

Linuron

Lorox

1,500

5

—

DuPont

MAMA
MCPB
MCPA
MCPP
Methyl bromide
Metobromuron
MH (a mine)

Ansar, Methar
Various brands
Various brands
Mecoprop, Mecopex
Various brands
Patoran
MH-30

4
720
—
—
700
4
4
650
1 7 ppm (air) 2
2,700
4
2,340
4

—
—
4
—
2
5
5

Ansul, etc.
Chipman

Monuron
Monuron -f- TCA
MSMA

Telvar
Urox-Various
Weed-E-Rad, Ansar

3,500
2,300
700

4
4
4

4
—
—

Norea
NPA

Herban
Alanap (Na. salt)

2,500
1,770

4
4

5
5

Hercules
Naugatuck-div.
U.S. Rubber

Paraquat
PBA
PCP (Na. salt)
Pebulate
Petroleum solvents
Picloram
PMA
Prometone
Prometryne
Propanil
Propazine
Pyrazon (PCA)

Paraquat
Benzac, Zobar
Weedbeads
Tillam
Various brands
Tordon
PMAS, TAT-C-Lect
Prometone
Caparol
Stam F-34, Rogue
Propazine
Pyramin

157
700
210
1,120
—
8,200
40
2,980
3,750
1,384
5,000
3,600

3
4
3
4
4
5
2
4
4
4
4
4

3
—
1
4
1
4
2
5
5
5
5
—

Chevron
Amchem
Monsanto, etc.
Stauffer

Dow
Cleary Corp.
Geigy
Geigy
Rohm-Haas
Geigy
Amchem

Sesone
Siduron
Silvex
Simazine
SMDC
Sodium arsenite
Sodium Chlorate

Sesone
Tupersan
Kuron, Weedone-TP
Simazine
Vapam
Atlas A
Atlacide

1,000
2,500
500
5,000
285
10
850

4
5
4
4
3
2
4

4
5
4
5
3
1,2
4

Un. Carbide
DuPont
Dow, etc.
Geigy
Stauffer
Allied
Chipman-etc.

Table salt (NaCI)
TCA

(For comparison)
Various brands

3,320
3,370

4
4

5
2

Chipman
Dow, etc.
CIBA
Naugatuck-div.
U.S. Rubber
DuPont
Ansul

Dow, etc.

�Toxieity Response of Small Animals to Indicated Herbicide Dosages
Some Common Trade
Names

Common Name or
Designation

Terbacil
Triallate
Trifluralin
2, 3, 6-TBA
2,4-D
2, 4-DB

Sinbar
Avadex BW
Treflan
Trysben, Benzac
Various brands
Butyrac, Butoxone

2, 4-DEP
2, 4, 5-T

Falone
Various brands

Vernolate

Vernam

Federal Insecticide, Fungicide, and Rodenticide
Act; from "Clinical Toxicology of Commercial
Products" by Gleason, M.N., Gosselin, R. E., and
Hodge, H. D. Williams and Wilkins Co., Baltimore, Md., 1963; from 1966 Pesticide Manual,
North Carolina State University; and from data
supplied by numerous basic product manufacturers.

Discussion

Before any herbicide can be marketed, it's toxicity to animals must be registered with the Department of Health, Education and Welfare, and
its usefulness as an herbicide must be established
with the U. S. Department of Agriculture. These
dual regulations place very strict requirements on
the development, federal registration, and labeling
of all herbicides. These rigid regulations are undoubtedly responsible, in part, for the extremely
low number of known cases of herbicide poisoning.
However, accidents do happen and severe errors have been made. The major difficulties have
been:
1. failure to read the label.
2. availability to small children.
3. carelessness in handling, leaving containers
open, not destroying old containers.
Federal regulations also extend to limiting the
quantity of any herbicide that can remain as a
residue in any treated crop.

ID-50

Mg./Kg.

Ingested
Dermal
Toxieity
Response
Rating* Rating**

500
500

5
4
4
4
4
4

4
5
4
—

850
300

4
3

4
4

1,780

4

Mfg.

Company***

4

7,500

1,340
3,700

1,644

5
3

DuPont
Monsanto
Elanco
DuPont, etc.
Chipman
Amchem
Naugatuck
Stauffer

Poison Control Centers

Pocatello—Poison Control Center, College of
Pharmacy, Idaho State College 233-2160 Ext.
254 — Night — 233-5587, 233-2638, 233-7204,
John V. Bergen, Ph.D.
Spokane, Poison Information Center Deaconess Hosp., W. 800 5th Ave., Riverside 7-4811, A.
Greer, M.D., E. Erickson, R.N.

Food inspection for pesticide residues is constantly in progress and several shipments with
residues in excess of tolerance have been seized
and destroyed. To assure the highest quality of
food, inspection and detection services are provided by both Federal personnel and by our Idaho
State Department of Agriculture.
The ultimate question is, what influence have
herbicides and other pesticides had on public
health? Recently Drs. R. C. Teal, M. D., and C. H.
Hine, M. D., Ph.D., representing the California
Medical Association testified as follows:
1. "There has been no increase in morbidity
(proportion of diseased persons) due to the ingestion of agricultural chemicals."
2. "Surveys show—the total public health has
improved by the use of pesticides."
3. "Pesticides constitute only a moderate
health hazard."
4. "Accidental ingestion by children and adults
is due to careless handling. Therefore, more educational efforts are desirable."

PUBLISHED AND DISTRIBUTED IN FURTHERANCE OP THE ACTS OF MAY 8 AND JUNE 30, 1914,
BY THE UNIVERSITY OF IDAHO AGRICULTURAL EXTENSION SERVICE, JAMES E. KRAUS,

DIRECTOR; AND THE U.S. DEPARTMENT or AGRICULTURE, COOPERATING.

P.O. 1892—3M-9-67

JAMES E. KRAUS, Director

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                  <text>&lt;p style="margin-top: -1em; line-height: 1.2em;"&gt;The Alvin L. Young Collection on Agent Orange comprises 120 linear feet and spans the late 1800s to 2005; however, the bulk of the coverage is from the 1960s to the 1980s and there are many undated items. The collection was donated to Special Collections of the National Agricultural Library in 1985 by Dr. Alvin L. Young (1942- ). Dr. Young developed the collection as he conducted extensive research on the military defoliant Agent Orange. The collection is in good condition and includes letters, memoranda, books, reports, press releases, journal and newspaper clippings, field logs and notebooks, newsletters, maps, booklets and pamphlets, photographs, memorabilia, and audiotapes of an interview with Dr. Young.&lt;/p&gt;&#13;
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