1 15 1 https://www.nal.usda.gov/exhibits/speccoll/files/original/540344e8f9e76df4b7bf8d3dc10b45f5.pdf 9cfadd8db61d5708776c5e405f89dad0 PDF Text Text Item D Number °5189 Author Dominick, David D. D (jot Scanned Corporate Author Report/Article Title Environmental Protection Agency, Trichlorophenoxyacetic Acid, Intent to Hold Hearing and Statement of Issues JOUmal/BOOk Title Federal Register Year 1979 Month/Day Julv24 Color Number of Images D ° Descrlpton Notes Friday, March 01, 2002 Page 5189 of 5263 �flDIRAl RtCIStfR, VOl. 3d, NO. 141—TULSDAY, JUtY 54, 1973 19R50 11)800 38 ENVIRONMENTAL PROTECTION AGKNCY ' 2,4,5-TniCHLOPOPhtNOXYACETIC ACID Intent To Hold Hearing Please take notice tint pursuant to the authority vested in me by section 6U>) <2) of the Federal Insecticide, Funr.iclde and Rodcnticldc Act, as amended, I hereby issue a notice of my intention to hold a hearing on all registered uses of 2,4,5TrichlorophenoxyiieeUc Arid • (2,1,5-T) other than on the iisc for rice which was was cancelled on May 1, 1070 (USDAPRD 70-13), as reainrmed by Order of August 6, 1071 (36 FH 1477, AUK, 11, 1971). It is my intention that the public hearing concerning the use on rice, (I. P. & n. Consolidated Docket Nos. 42, 44, 45 & 48) be consolidated with the hearing I have called today for all other uses and that all hearings commence in April, 1974. The start of the hearing is being delayed until then to permit the Agency to complete :m environmental and human monitoring project on the presence of the tetnichlorodioxin impurity found in 2,4,5-T and the extent to which the dioxin may adversely a f f e c t human and animal health. Please take further notice that any person wislunfl to become a p a r t y to this hearing called by me today on all oilier uses of 2,4,5-T shall file a response to the. accompanying statement ol issues, published herewith, with t h e Hearmc Clerk, Environmental Protection Agency, Waterside Mall, Washington, D.C. 204GO, on or before August 23,1973. Done this 19th day of July 1973. DAVID D. DOMINICK, .Assistant Administrator for Hazardous Materials Control. (PU Doc.73-16189 Tiled 7-23-73;8:45 am] 2,4,5'TRIClll.OROPHCNOXYACt:TIC ACID Stalcmcnt of Itsuc-s Pursuant to the accompanying; notice of intent to hold a hearing, it Is hereby ordered that the followinn issues be addressed by such hearing together with any other issues which the Administrative! Law Judpc deems relevant, namely: I. Whether 2,4.5-Trlchloropheno.xyacetlc Acid (2,4,5-T) products presently registered, or other material submitted in support of these registrations, complies with the provisions of the Federal Insecticide, Fungicide and Rocicntlclde Act, as amended; and II. Whether 2,4,5-T will perform its Intended function without unreasonable adverse effects on the environment. in. Whether, when used In accordance with widespread and commonly recoriilzod practice, 2,4,b~T generally causes trnrea-sonnble adverse effects on the environment, as defined by the Fedcial Insecticide. Funeicldc and Kodenticide Act, as amended. IV. Whether the registrations of 2.4,5-T should be cancelled or its clas.sifl"'Hlon changed. V. The answers to these issues should relate to thr following subsidiary qurstion.s, as wi-11 as to the ten Issues d e l i n e ated In the 2,4,5-T Orders of the A d m i n istrator ol November 4, 1971 and April 13, 1372; (I. F. & R. Docket No. 42 and No. 44) and to such additional questions as the A d m i n i s t r a t i v e Low Judge finds relevant, namely: A. The health hazards to man and to other animals which may be caused by 2,4,5-T and/or Its rxl.remely toxic contaminant, 2,3,7.U-tctrachlorocliben70-i>dioxin (TCIJU), with emphasis on the following: 1. Is 2,4.5-T or TCDD ft tenvtoi'en? 2. Doca 2,4.n-T or TCDI) Induce other adverse reproductive! piiects? 3. Is 2.4,.r>-T or TCDD n m u t a n e n ? 4. Its 2.4,5-T or Tt:])D a cari-lni-rcn'' 6. Cnu<.'>:po.',ure to 2.4,5'Tor 'iron I n c l i n e oub-lotlml chronic health eCeots? 6. Can chronic, low-lovH r s f n v . u r o ti> 2.4.5T imcl/or M C D D cause delayed l e l l n i l l t y ? IJ T)ie extent of the health risk'for m n n and other animals tx>R«l by H.4.5-T and TCDD, with emphasis on the following conditions: 1. Can additional TCDD be gencralod In thu Environment, by tho thermal strcsa of 2,4,5-T or Its metarjoirt'o? 2. Ccm 2.4,.r>--T or TCDD persist und blonccumulate In tlio environment? 8. What arc the tivenue-s of hurmiu and animal exposure to 2,4 5-T and TCDD? For example, «ui ucrlal drift or water tmiu,por. of 2,4,5-T or TCDD cause mo\«n\cvkt of lUcss compounds away from t!-,c site of application 1 4. Are 2,4.5-T or TCDD residues bclni; stored and Becumula'ed In the human footf supply and In h u m a n and animal tissue. Inclvullng humnns and wildlife directly exposed to 2,4.5-T? 6. Arc other clloxlns and elm'lar cont.vmlnanU, besides TCDD, present In 2.4 5-T and. If to, what rU'k.5 to h e a l t h do they constitute' 1 C. Whtvt are other envlromncnUl sources of dloxlnr, particularly TCDD. and do thtse scmrcfcs enhunco tho total dioxin body burden and exacerbate the h e u l t h risks rnl.icr) by 2.4.5--T mid related TCDD? 7. What are the current levels of dloxlnr, in registered 2,4.5-T products and In technical matctlul vi.U'd to formulate tlicst) products 1 0. Do the current methods of m a n u f a c t u r e of 2.1,5-T provide for con.MPtcntly low level* of dU-xln;; in the final u-chnl.'al product and what arc the q u a l i t y control measures us«d to mlnlmli'O dioxin levels? C The necessity for the continuation of cho registered uses of 2,4,5-T, with emphasis on the following: 1. What arc the pests which each rcclstercd xi&o Is intondi'j to control and the de-. grec of control achieved by cuch use? 2. What Li tho ccmt. timing, and ruto of uppUcfttlon of 2,4,5-T for each use? 3. -What alternative? controls exist for *ach registered u.no and what la the cost and offc'ctlvcnc-sH of each altcrnatlvo. 4. Do a l t e r n a t i v e pc.-,llclde prodvicta caviseadverse e i i v l r i . n m r n t a l vlliv.ta? 5. What are the economic Implications of tlicsu alternatives, Including that of no control? Done tliis 19th day of July 1073. DAVID D. DOMINICK, Assistant Administrator /or Hazardous Materials Control. [TO Doc 7;1-151<JO Hied 7 - 2 3 - f 3 ; B ; 4 8 am) |I. F. ft U. Docket No. 2D5) �*"••• * 39 1. A contaminant of 2,4,5~T ,— tetrachlorodibcnzoparadioxin (TCDD, or dioxin) — is one of the most tet-atbgdnte chemicals known. The registrants have not established that 1 part per million of this contaminant — or even 0.1 ppni — in 2,4,5~T does not pose a danger to the public health arid safety, 2. There is a substantial possibility that even "pure" 2,4,5-T is itself a hazard to man and the environment. 3. The dose-response curves for 2,4,5-T and dioxin have not been determined, and the possibility of "no effect" levels for these chemicals is only a matter of conjecture at this time. 4. As with another well-known teratogen, thalidomi.de, the possibility exists that dioxin may be many times more potent in humans than in test animals (thalidomide was 60 times more dangerous to humans than to mice, and 700 times more dangerous than to hamsters; the usual margin of safety for humans is set at one-tenth the teratogenic level in test animals). 5. The registrants have not established not accumulate in body tissues. that the dioxin and 2,4,5-T do If one or both does accumulate, even small d«.->es could build up to dangerous levels within man and animals, and possibly in the toot! chain as well. 6. The question of whether there are other sources of dioxin in the environment has not been fully explored. Such other sources, when added to the amount of dioxin from 2,4,5-T, could result in a substantial total body burden for certain segments of the population. 7. The registrants have; not established that there is no danger from dioxins other than TCDD, such a:; th.C'hexa- and heplndioxln Isomera, which also can be present in 2,4,5-T, and which arc known to be teratogenic. �40 8. There in evidence that the polychlorophenolo in 2,4,5-T may decompose into dioxin when exposed to high temperatures, such as might occur with incineration or even in the cooking of food. 9. Studies of medical records in Vietnam hospitals and clinics below the district capital level suggest a correlation between the spraying of 2,4,5-T defoliant and the incidence of birth defects. 10. The registrants have not established the need for 2,4,5~T in light of the above-mentioned risks. Benefits from 2,4,5-T should be determined at a public hearing, but tentative studies by this agency have shown little \ necessity for those uses of 2,4,5-T which are now at issue. � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Alvin L. Young Collection on Agent Orange Description An account of the resource <p style="margin-top: -1em; line-height: 1.2em;">The Alvin L. Young Collection on Agent Orange comprises 120 linear feet and spans the late 1800s to 2005; however, the bulk of the coverage is from the 1960s to the 1980s and there are many undated items. The collection was donated to Special Collections of the National Agricultural Library in 1985 by Dr. Alvin L. Young (1942- ). Dr. Young developed the collection as he conducted extensive research on the military defoliant Agent Orange. The collection is in good condition and includes letters, memoranda, books, reports, press releases, journal and newspaper clippings, field logs and notebooks, newsletters, maps, booklets and pamphlets, photographs, memorabilia, and audiotapes of an interview with Dr. Young.</p> <p>For more about this collection, <a href="/exhibits/speccoll/exhibits/show/alvin-l--young-collection-on-a">view the Agent Orange Exhibit.</a></p> Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Box The box containing the original item. 176 Folder The folder containing the original item. 5189 Series The series number of the original item. Series VIII Subseries I Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Dominick, David D. Source A related resource from which the described resource is derived Federal Register Date A point or period of time associated with an event in the lifecycle of the resource July 24 1979 Title A name given to the resource Environmental Protection Agency, Trichlorophenoxyacetic Acid, Intent to Hold Hearing and Statement of Issues ao_seriesVIII