1 15 1 https://www.nal.usda.gov/exhibits/speccoll/files/original/9dcaded8d2bbcd39c95c18efd31ca478.pdf 9f28a744696fc3e19a2e7c3e0c04a12a PDF Text Text item D Number 0576 Author Young Alvin L ° Not Scanned Corporate Author Report/Article Title Tn 'P ReP°rt - s - °- TA-1578 (21 sep 79) Journal/Book Title Year ™™ Month/Day October 17 Gotor D Number of Images ° DeSCriptOU NOtOS Attachments 2 (VACO Agenda) and 5 (proposed questions for position papers) are missing. Attachments 1, 3, and 4 were not scanned with this item, but were scanned for item 5756. Thursday, March 28, 2002 Page 5760 of 5780 �DEPARTMENT OF THE AIR FORCE USAF SCHOOL OF AEROSPACE MEDICINE (AFSC) BROOKS AIR FORCE BASE, TEXAS 78235 REPLY TO ATTNOF: , H . EKS ' 1 « SUBJECT: Trip Report - S.O. TA-1578 (21 Sep 79). EK CEA CE CD CC TS IN TURN '!, Places visited a. Veterans Administration Central Office (VACO), Washington DC, 24 Sep 79 b. HQ USAF/SGES and HQ USAF/CVAH (Air Force History), Boiling AFB DC, 25 Sep 79 c. The Environmental Sciences Laboratory, Mount Sinai School of Medicine, New York, NY d. VA Conference on the Health-Related Effects of Exposure to Agent Orange, 27-28 Sep 79, Hospitality House, Arlington, VA 2. Personnel contacted a. VACO Participants in VA Advisory Committee on Health-Related Effects of Herbicides (Attachment 1) b. HQ USAF Maj Phillip Brown, HQ USAF/SGES Capt D. Rightmyer, HQ USAF/CVAH c. Mount Sinai School of Medicine Irving J. Selikoff, M.D., Director, The Environmental Sciences Laboratory Henry A. Anderson, M.D., Assistant Professor of Community Medicine Marion Moses, M.D., Resident in the Department of Community Medicine �d. VA Conference Speakers listed on Program Agenda (Attachment 2) Lyndon Lee, M.D., VACO, Washington DC Lawrence B. Hobson, VACO, Washington DC Paul DeGovin, M.D., VACO, Washington DC 3. Topics Discussed a. VACO The purpose for visiting the VACO was to attend and participate in the second meeting of the VA Advisory Committee on Health-Related Effects of Herbicides. The objectives and scope of the Committee is described in the Committee's Charter (Atch 3). The agenda for the Committee meeting is provided in Attachment 4. Items of .special interest included: (1) Reports of the VA Steering Committee (a) As of 31 Aug 79, 3,100 Vietnam Veterans alleging exposure to Herbicide Orange have been examined in VA Hospitals. Approximately 2,900 of these have been found to be clinically asymptomatic. (b) As of 31 Aug 79, 625 claims for compensation have been filed by Vietnam Veterans alleging exposure to Herbicide Orange. Approximately 435 have claimed specific disabilities, while 190 have claimed only herbicide exposure. All cases claiming only herbicide exposure were denied, while 416 of the 435 claiming a specific disability were denied. The remaining 19 claims were allowed: one (1) allowed for chloracne and 18 allowed for disabilities originating during or 1 year after service, but unrelated to VA criteria for herbicide exposure. (c) Fat biopsy has been performed on 34 volunteers. Twenty-one (21) of these individuals were Vietnam Veterans alleging exposure to Herbicide Orange; 3 were active duty Air Force personnel associated with the Herbicide Orange disposal project (PROJECT PACER HO); and 10 were controls (veterans not assigned in Vietnam). Twenty-two of the fat samples have been analyzed for TCDD at the parts per trillion level by the Department of Chemistry, University of Nebraska, Lincoln NE. The remaining samples are to be analyzed by 12 Oct 79. The VA is planning to have an "in-house" committee review the analytical results on 21 Oct 79 in Chicago. �(d) The VA has established a tissue registry with the Armed Forces Institute of Pathology (AFIP), Washington DC. Any pathological tissues removed from Vietnam Veterans alleging exposure to Herbicide Orange are sent to AFIP for examination, diagnosis and retention. A report from AFIP is then filed with the VA. AFIP will monitor for any unusual or unique tumors, or tumors occurring at an unusually young age in the Veterans or for an increase in tumors in a specific military unit that served in Vietnam. As of Jul 79, 13 cases have been examined, including 7 tissues removed during surgical procedures, 5 during autopsy and 1 seminal fluid. (e) VACO is computer coding all medical data from the examination of all Vietnam Veterans alleging exposure to Herbicide Orange. When the coding is completed (^ 1 month), a printout of symptom frequencies, diagnoses, clinical results, etc. will be available. (2) Discussion of Position Papers The Advisory Committee was asked on 11 Jun 79 to answer 13 questions prepared by the VA Steering Committee, Accordingly, at that, time, Dr. Haber asked selected Advisory Committee members to prepare a draft position paper on each of the questions. Attachment 5 is a list of the proposed questions and the individual responsible for preparing a draft. On 24 Sep 79, draft position papers were discussed on 10 of the 13 questions. No drafts were available on questions 3, 10, and 13. (3) Presentations by L.t Col Wolfe and Major Young At the request of HQ USAF/SG, two presentations were given to the Advisory Committee to assist them to better understand the way in which herbicides were used in Vietnam, what data are available in developing exposure criteria, and what diagnostic approaches might be used to evaluate herbicide toxicity. Vu-graph outlines for both presentations are provided as Attachments 6 (Major Young) and 7 (Lt Col Wolfe). b. HQ USAF/SGES, HQ USAF/CVAH On 25 Sep 79, a visit was made to HQ USAF, Boiling AFB. Discussions on the RANCH HAND II protocol were held with Major Brown, The visit to the Air Force History Office was made in order to examine RANCH HAND historical records maintained by Capt Rightmyer. Eleven names, dates of tours and number of herticide missions were obtained �on RANCH HAND personnel. Only two of twelve boxes of RANCH HAND historical data were examined. t c. Environmental Sciences Laboratory, Mount Sinai On 26 Sep, the Environmental Sciences Laboratory was visited. Brief discussions were held with Drs Selikoff, Anderson, and Moses concerning the RANCH HAND protocol. Dr. Selikoff emphasized (a) that criteria for the mortality study should be established prior to initiation of study; (b) matched group analysis could be employed to prevent loss of data; (c) when a subject is contacted, the name of a referral should be obtained so that if the subject were to move during course of study, the referral would have the change of address; (d) more detailed information should be obtained on reproduction, fertility and miscarriages; and (e) matching of controls with the RANCH HAND personnel should also be done on a geographic basis. Dr. Moses briefly discussed the status of her study on the Monsanto Workers at Nitro West Virginia. No definitive conclusions are available at this time. d. VA Conference, Arlington VA This Conference was held to inform physicians from each of the 160 VA Hospitals of the VA Central Office program for studying health-related effects of herbicide exposure in Vietnam Veterans. Mr. Max Cleland, VA Administrator, set the tone of the conference by emphasizing VA's concern for Veterans alleging exposure to Herbicide Orange. He stated that "at the very least, the Agent Orange Syndrome is characterized by FEAR, and it should be every VA physician's responsibility to show concern and understanding to ey_ery_ Vietnam Veteran that contacts or visits a VA hospital claiming exposure to Agent Orange". The agenda for the conference is provided in Attachment ?.. Dr. Wolfe and I presented the same presentations as were presented 24 Sep at the VA Advisory Committee meeting. We received enthusiastic responses from not only the conference attendees but also from the VA Central office staff. 4. Items of interest to procurement and USAFSAM programming: None 5. Information of interest to other USAFSAM divisions or branches: BR9 NG. 6. This TOY was performed in support of EPI ranch project. �7. This report contains information worthy of filing in TSK, ALVIN -LVYCfUNG, Hlaj, USAI Consultant, Environmental Sciences 7 Atch 1. Advisory Committee Membership 2. VACO Agenda 3. Charter of VA Advisory Committee 4. Committee Meeting Agenda 5. Proposed Questions for Position Papers 6. Vu-Graph Outlines (Major Young) 7. Vu-Graph Outlines (Dr. Wolfe) ��FACTORS TO BE CONSIDERED TIME BETWEEN THE EXPOSURE AND TH! DURATION OF THE EXPOSURE LAG TIME/INCUBATION PERIOD CONFOUNDING EXPOSURES �PROBLEMS UNIQUE TO PHENOXY MIXTURE OF TWO ACTfVE COMPOUNDS AND ONE CONTAMINANT LACK OF CLEARLY DEFINED AND OBJECTIVE END POINTS WIDE RANGE OF PRESUMED EFFECTS CONFUSION- BETWEEN ACUTE, SUBACUTE AND CHRONIC EFFECTS DIFFICULTIES IN VERIFICATION OF EXPOSURE �SUMMARY CHARACTERISTICS OF AS OF 30 1979 8F 381 SEX: 1-08% MALE [84% MEAN AGE; 34 MEAN OF PER 2.3 OF US US • US AR US NAVY . 66,4% 17,4% 11.2% 5.0% �PERCENT OF CLAIMS BY . CATEGORY 23 15 . ' 13 1 6 EAR/NOSE.THROAT ' 5 N - 417CLAI 190 ALLEGED "EXPOSURE" ' �OF IN 2,4-D TC00 PMPHYRIA • • • • NEUR HYPEtPiSfiENTATION ASTHENIA • • • • LIVER • LIVER • • G! * G? • &i * • • HYPOTHYROIDISM • @ CSF • CONVULSIONS ABNORMALITIES DISTURBANCES i -ifi �COMPONENTS OF SELECTED HUMAN SYMPTOM/SIGNS F31 LOWING f EXPOSURE TO PHENOXY HERBICIDES AND/OR TCDD NEURO-PSYCHiATmC ABNORMALITIES PERIPHERAL ASTHENIA ANXIETY DEPRESSION FATIGUE HYPOREFLEXIA WEAKNESS PARESTHESIAS LOSS OF LIBIDO IMPQTENCY SLEEPLESSNESS MYALGIA GAIT DISTURBANCE "MILD" PARESIS ANOREXIA DIZZINESS ^LEARNING ABILITY DERMATOLOGiC DISEASE CHLORACNE CUTANEA TARDA HYPERPIGMENTATION HIRSUT1SM [BODY] ALOPECIA OF THE SCALP �OF TO TCDJ LDH . NAUSEA - •we ATRfAL FIBRILLATION SASTRITiS ABD PAIN FLATULENCE �ACTIVE < NANT iLAOC OF CLEARLY DEFINED END POINTS DE RANGE OF PRESUMED EFFECTS CONFUSOST BETWEEN ACUTE, SUBACUTE AND CHRONIC EFFECTS DIFFICULTIES IN VERIFICATION OF EXPOSURE J �UMFTED EXAMINATION OF THE PATIENT COMPREHENSIVE STUDY OF THE PATIENT AND FAMILY �•*!«:**-H*!1 EXAMINATION �PHYSICAL DERMATOLOGIC EXAMINATION NEURO-PSYCHIATRIC EVALUATION LIVER FUNCTION EVALUATION �' • r j 'riJj'.*. S .;-"H£3$? GENERAL PHYSICAL EXAMINATION DtRMATOLOGiC EXAMINATION NEURO-PSYCHiATRIC EVALUATION LIVER FUNCTION EVALUATION REPRODUCTFVE EVALUATION IMMUNOLOGiC EVALUATION ENDOCRINE EVALUATION �PHENOXY HERBICIDES RESULT IN VERSE HEALTH EFFECTS? �OF OF Or 1f024 |ALL TO TCDD IN JULY 1978. SEVESO, ITALY CLINICAL BOTH WEST LONG TERM OF 2.4.5-T DOW Oi F & FA! F 238 D TO TCDO I OF 204 MALE OF fllCAL OF IN 2,4,5-T CZECHOSLOVAKIA TEN YEAR OF 80 TO TCDD IN 1965-68. CASE IN OF 4,500 � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Alvin L. Young Collection on Agent Orange Description An account of the resource <p style="margin-top: -1em; line-height: 1.2em;">The Alvin L. Young Collection on Agent Orange comprises 120 linear feet and spans the late 1800s to 2005; however, the bulk of the coverage is from the 1960s to the 1980s and there are many undated items. The collection was donated to Special Collections of the National Agricultural Library in 1985 by Dr. Alvin L. Young (1942- ). Dr. Young developed the collection as he conducted extensive research on the military defoliant Agent Orange. The collection is in good condition and includes letters, memoranda, books, reports, press releases, journal and newspaper clippings, field logs and notebooks, newsletters, maps, booklets and pamphlets, photographs, memorabilia, and audiotapes of an interview with Dr. Young.</p> <p>For more about this collection, <a href="/exhibits/speccoll/exhibits/show/alvin-l--young-collection-on-a">view the Agent Orange Exhibit.</a></p> Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Box The box containing the original item. 204 Folder The folder containing the original item. 5760 Series The series number of the original item. Series VIII Subseries III Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Young Alvin L. Date A point or period of time associated with an event in the lifecycle of the resource October 17 1979 Title A name given to the resource Trip Report - S. O. TA-1578 (21 Sep 79) ao_seriesVIII