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&lt;p&gt;For more about this collection, &lt;a href="/exhibits/speccoll/exhibits/show/alvin-l--young-collection-on-a"&gt;view the Agent Orange Exhibit.&lt;/a&gt;&lt;/p&gt;</text>
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Corporate Author
Ronort/ArtlGlB Title Letter: [from Alvin L. Young] to Michele Flicker, [May 14,
P
1985]

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000

°

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^

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Descripton Notes

Wednesday, June 06, 2001

Page 1673 of 1688

�DR. MICHELE FLICKER
VAMC
4801 LINWOOD BLVD
KANSAS CITY,MO 64128
DEAR MICHELE
Thank you for sending the data from
Rappe's paper.
I hope that his present-ation and that of Hardell was worth
while.
I talked with Dr Houk today (Hay 14)
about contributing at Eayreuth on both
Risk Assessment and Status of CDC Studies on Agent Orange/Dioxin. We
had the opportunity to discuss the VAX
EPA ADIPOSE TISSUE STUDY- Without a
doubt he feels that he can contribute
and support the study,, Count on him
to furnish standards and quality control assistance., Thus? I believe that ono
the AOWG approves the protocol? it will be time to ask all three agencies for
the financial resources to conduct the
study.
Please keep me informed of your progress on the protocol and if you can draftup cost estimates to complete the task
it wouId be worth having them»
Best wishes.,
Sincerely

�</text>
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DOSCriptOD NOtOS

Includes "Agent Orange Controversy: Is Agent Orange
Responsible for Health problems Reported Among
Vietnam Veterans?", OSTP Issue 1981-1988; Agenda
for the Domestic policy Council Agent Orange Working
Group at DHHS; "Air Force Health Study: Study
Overview and Update," Air Force Systems Command;
three articles, "Agent Orange: An American Tragedy",
Joe Cole, The Stars and Stripes National Tribune,
November 14,1988, "Legion Testimony Attacks CDC
Study of Agent Orange", The Missouri Veterans News,
"The Declassified War", Anthony L. Kimery, Veteran,
November/December, 1988; correspondence from
Congress to Donald M. Newman, Chairman, Agent
Orange Working Group, November 22,1988;
memorandum from National Vietnam Veterans
Coalition, November 1988, No. 48, "Agent Orange:
Pending New Legislation"

Tuesday, May 15, 2001

Page 1469 of 1514

�OSTP ISSUE
1981-1988

AGENT ORANGE CONTROVERSY

Is Agent Orange Responsible
For Health Problems Reported
Among Vietnam Veterans?

�BACKGROUND
From 1965 to 1970, USAF Applied in
Tactical Operations in South Vietnam,
&amp;

42 Million Liters of Agent Orange.

2.5 Million Military Personnel From the
U.S., Australia, New Zealand and South
Korea Served One-Year Tours During the
Same Period.

BACKGROUND (Cont'd)

�Beginning in 1978 Many Veterans Of
That Era Reported Medical Problems
That They Believed Stemmed From
Exposure To Agent Orange During Their
*»
Military Assignment.

Complaints Have Ranged From Tingling
In the Extremities To Skin Disfigurement
And Rare Forms Of Cancer. Some
Veterans Have Fathered Children With
Birth Defects.

�DPC AGENT ORANGE WORKING
GROUP (AOWG)
o

1981 President Reagan Established the
AOWG.
&lt;5&gt;

-

Chaired By Under Secretary Of HHS

-

Serves As Overall Coordinator,
Clearinghouse, And Evaluator Of The
Federal Research Efforts

o

Policy Group - HHS, DOD, VA, OMB, OPD
and OSTP

o

Science Panel - CDC, NIOSH, NIEHS, NCI,
Air Force, OSHA, EPA, USDA, DOS, &amp; OTA

�STATUS OF AOWG ACTIVITIES
o • In The Past 7 Years, AOVVG Provided
Oversight To 10 Major Health Studies And 5
Major Health Surveillance Programs.
• ' • • ' ' .

o

•

*

Federal Agencies Have Expended $200 M
On Human, ToxicologicJAnd Environmental
Studies.

o

i"

CDC/Air Force Developed State-Of-The-Art
Methods For Detecting And Verifying
•

• . - . - • .

:

• •

i

Exposure.
o

Serum Dioxin Studies Completed On
Ground Troops.

�Serum Dioxin Analyses Underway For
Cohorts In Air Force Health Study (The Men
Who Served in AF Defoliation Program In
SEA And Their Matched Controls).

�FINDINGS
To Date, No Major Health Effects (Mortality,
Cancer Or Birth Defects In Children) Can Be
»

Associated With Agent Orange Exposure in
Vietnam.

�RECOMMENDATIONS

Retain DPC Agent Orange Working Group
Retain HHS As Chair
Within 18 Months, CDC Rare Cancer Study
And Air Force Health Study Will Be

Completed.
Publish Findings, Brief Congress
Close-Out AOWG

�**
»
s
&lt;

DEPARTMENT OF HEALTH &amp; HUMAN SERVICES

office of the Secretary

\
*0

Washington, D.C. 20201

AGENDA FOR THE DOMESTIC POLICY
COUNCIL AGENT ORANGE WORKING GROUP
December 6, 1988

-

2:00-3:00 P.M.

Welcome and Introductions

Report from DOD

Chairman Don Newman

Admiral Edward Blasser ,DAS/Defense

A presentation by Major-General James Sanders, Air Force
Deputy Surgeon-General and the USAF Health Study (Ranch
Hand) team.

Report from Chairman Science Panel

Remarks from the Veterans Administration

Dr. Vernon Houk

Don Ivers

Other business from Members

Chairman Don Newman

Closing remarks

Chairman Don Newman

�DECEMBER 1988
BRIEFER:
COL WILLIAM H. WOLFE

EK-RT-i; -.1

�SERUM DIOXIN STUDIES

ASSAY DEVELOPED AT CDC TO DETECT DIOXIN IN SERUM
AT PARTS PER TRILLON LEVEL
JOINT USAF/CDC EFFORTS:
HALF-LIFE STUDIES (7.1 YEARS)
ASSAY OF AFHS PARTICIPANTS
PRETEST OF 200 DEMONSTRATED ASSAY VALIDITY
RANCH HAND MEAN = 48.0 PPT
COMPARISON MEAN =

4.8 PPT

EXPANDED STUDY OF 2010 PARTICIPANTS
TO BE COMPLETED IN 1989
FUNDED BY HQ AFSC WITH REIMBURSEMENT FROM
EXCESS VA^ FUNDS (S.11)

/

j

DETAILS OF TRANSFER BEING ARRANGED
FUNDS TO COVER COST OF ASSAYS AND ANALYSIS

J
EK-RT-12-11 881122

�STATUS TO DATE

SERUM DIOXIN VALUES IN AFHS PERSONNEL
GROUP

"NUMBER

MEAN

RANCH HAND

283

35.0

COMPARISON

246

4.8

RANGE
1.6 - 313
0 -

84

1 6

~313

RANCH HAND
ENLISTED GROUND

184

46 3

'

'

OTHER OCCUPATIONAL STRATA ARE TOO SPARSE
FOR ANALYSIS AT THIS TIME

J
SAM/LS-10-11 881122

�AIR FORCE HEALTH STUDY
250 -r

SERUM DIOXIN RESULTS

200--

COMPARISONS

150- -

RANCH HANDS

NUMBER OF
PARTICIPANTS
100:,

50--

•llllil

0-9

10-19

20-49

50-99

SERUM TCDD LEVEL (ppt)

100-199

200 or
^ more

�SCHEDULE OF REPORTS

REPORT

PUBLICATION DATE

1989 MORTALITY UPDATE
COMPARISON COHORT EXPANDED
(N=19, 101)

WINTER 1988/1989

BIRTH DEFECT REANALYSIS
BASED ON FULLY VERIFIED DATA

SUMMER/FALL 1989

THIRD MORBIDITY REPORT

FALL/WINTER 1989

SAM/LS-10-4

881122

�FUTURE PLANS

1989

COMPLETE SERUM DIOXIN ASSAYS

1990

ANALYZE SERUM DIOXIN DATA AND PUBLISH REPORT

1991

PREPARE FOR AWARD OF CONTRACT FOR THIRD
FOLLOWUP EXAMINATIONS

1992

CONDUCT PHYSICAL EXAMINATIONS

1993

ANALYZE DATA

1994

PUBLISH REPORT

SAM/LS-10-13 881122

�AFHS ADVISORY COMMITTEE
ISSUES

SCIENCE PANEL OF THE AOWG STRONGLY SUPPORTS KEEPING
THE CURRENT ARRANGEMENT WITHIN DHHS
USAF PRINCIPAL INVESTIGATORS STRONGLY FAVOR CURRENT STRUCTURE
ANY ACTION BY USAF OR DOD TO MANAGE THE COMMITTE OR
SELECT ITS MEMBERS WILL GENERATE CHARGES OF INTERFERENCE OR
CONFLICT OF INTEREST

INTENSE CONGRESSIONAL INTEREST EMPHASIZES NEED TO
MAINTAIN SCIENTIFIC INDEPENDENCE

SAM/LS-10-10

881122

�AFHS ADVISORY COMMITTEE
RECOMMENDATIONS

RENEW CHARTER OF THE ADVISORY COMMITTEE
RETAIN RESPONSIBILITY FOR THE COMMITTEE WITHIN DHHS
SELECT MEMBERS AFTER REQUESTING NOMINEES FROM
VETERANS GROUPS
SELECT CHAIRMAN FROM CIVILIANS CURRENTLY SERVING
DR LEONARD KURLAND
DR RICHARD MONSON

SAM/LS-10-14

881122

�ADIPOSE TISSUE TCDD LEVELS
IN EXPOSED PERSONS
MISSOURI 1986
0 - 100 PPT
EXPANDED
HORSE ARENA
RESIDENTIAL
WASTE HAULING
TCP PRODUCTION

20

50

150

250

350

450

550

PARTS PER TRILLION (PPT)

650

750

60

100

�SENT BY.'Xerox Telecopier 7020 ;12- 5-58 ; 8-52AM

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VIETNAM VETERANS
(646 MEN)

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NON-VIETNAM VETERANS
(97 MEN)

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•
0
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•
0
40
•
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10
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RANCH HAND
GROUND CREW
(147 MEN)
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COMPARISON
GROUND CREW
(49 MEN)

TCDD (PARTS PER TRILLION)

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27821
27032

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20000 '

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(.17) (.59)

137

PERSONS FROM
UNEXPOSED AREA
(ZONE S)

PERSONS FROM
EXPOSED AREA
(ZONE A) WITH
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PERSONS FROM
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(ZONE A) WITH
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�"To C*r» For Him Who Stull
*n 6an&gt;« Th» Sctti* And
. Fo&gt; Ht* Wtahm And Ml. OrphtnAbrthMn Lincoln

.7

THE STARS AND STRIPES-THE NATIONAL TRIBUNE

14 NOVEMBER 1988

Agent Orange: An American Tragedy
In May 1983 officials of the Center for
Disease Control (CDC) recommend
evacuation of the Quail Run Mobile
Home Park near Times Beach, Missouri,
after EPA. officials find dioxin contamination in excess of four times that of the
town of Times Beach (1,100 ppb.). More
than 90 percent of the town of Times
Beach, located approximately 25 miles
southwest of SL Louis, Mo., was found to
be contaminated with more than 100 ppb.
of dioxin, according to a January 1983
report CDC officials warned the more
than 3,000 residents to stay away because
of health hazards.
Police were stopping the residents from
removing personal belongings out of fear
of spreading the contaminants to other
areas. Flooding of the Meramec River
may have further contaminated vast areas
of southern Missouri, Russell Bliss, owner of Russell Bliss

By Joe Cole
Drain Oil Service, has been identified as
the source of much of the contaminated
waste oils which were sprayed on over
100 sites in southern Missouri, including
Times Beach. The town of Times Beach
paid Bliss $4,800 for two applications of
the contaminated waste oils in 1971 and
1972. The federal government has since
paid a reported 34.5 million dollars for the
purchase of Times Beach, as pan of the
EPA Super-fund hazardous waste site
clean-up program.
Last April 1988, Mr. Brian Manza, a
disabled Vietnam veteran, visited the
Times Beach site, only to be turned away
by EPA officials, wearing "moon suits" as
Brian described them. Theentireareawas
fenced and posted as an extremely hazardous waste site. Brian's concerns are
obvious to Vietnam veterans who were
exposed to toxic chemicals in Vietnam.

Millions of gallons of Agent Orange,
contaminated with dioxin were sprayed
over vast areas of Vietnam. If two spray
missions using less than 5,000 gallons of
contaminated oil could do this to a town in
Missouri, what could millions of gallons
of oil-based herbicides contaminated
with dioxin at thousands of times the level
found in Times Beach do to a country
called Vietnam?
In 1986, the Centers for Disease Control
conducted blood serum studies of Vietnam veterans, as a possible method of
identifying those veterans who may have
been exposed to toxic chemicals while
serving in the Vietnam War. Their findings indicated that Vietnam veterans'
levels of dioxin in blood were similar to
those samples of persons who had not
served in Vietnam. Since the non-ex-

posed comparison group was selected
from the Times Beach and Southern
Missouri area, one can only speculate as to
the meaning of the studies results. Southern Missouri is no better nor worse than
Vietnam.
Last 7 July 1988, the Department of
Defense declassified documents which
revealed that the Defense Department-had
purchased a chemical plant at NVeldon
Springs, Missouri, which was to produce
8 million gallons of Agent Orange per
year by late 1969, over and above the
entire domestically produced product,
which was currently being used for defoliation in Vietnam.
Declassified USMACV reports indicate herbicide use in Vietnam during 1967
through 1969 was 11.9 million gallons per
year. V/eldon Springs, Missouri is located
approximately 25 miles west of SL
Louis.*

�THE MISSOURI VETERANS NEWS

PAGES

Legion Testimony Attacks
CDC Study of Agent Orange
WASHINGTON (ALNS) • smaller than the size of New
— The government has Jersey during the war. "It is
"fallen short of its responsi- absurd that the CDC says
bility" to compensate vic- that it cannot find enough
tims of Agent Orange expo- people to study," Sommer
sure, an American Legion said. He told the members
spokesman has told a House that the CDC developed a
subcommittee.
study that was "destined to
The statement submitted fail."
by John Sommer, director of
Basic research flaws were
the Legion's Veterans Af- committed by the CDC,
. fairs and Rehabilitation Di- Sommer said. Among the er1 vision, expressed serious rors made were what he
concern for the govern- called "cardinal sins of
ment's lack of responsibility epidemiology." First, the
in recognizing any problems CDC research diluted the efassociated with dioxin expo- fects of Agent Orange exposure. Sommer criticized the sure by including in the
Centers for Disease Control study group every person in
for its mishandling of re- Vietnam. For example,
search data, and for its about Lin every 5 men who
interpretation of the data the served in Vietnam actually
CpC researchers did gather. served in combat. The CDC
Sommer pointed out that "generalized" exposure to
the CDC study of Agent Agent Orange across the enOrange exposure was so tire service population in
limited by the restrictions Vietnam, so that the 20 per
upon just what veterans cent likely to be exposed
would be included that an was diluted by the other 80
accurate picture of these per cent of the non-exposed
veterans was not developed. men.
Veterans eliminated from
To further weaken the
the group which the agency . CDC's study, the veterans
looked at were those who who were not included in the
served more than one tour in . study took away the "statisVietnam, those who served tical power" of the potential
In a particular unit for fewer dioxin victims. "A knowthan 180 days, those who ledgeable epidemiologist
were above the rank of E-S, would try to optimize the
those who transferred from chance of observing an
one unit to another during effect by including, rather
their tour, and any veteran than excluding, the veterans
who served any number of who are most likely to have
days before or after the pro- suffered from exposures in
posed study window (Janu- question," Sommer said. '
ary, 1967-December, 1968).
Sommer also alleged that
The U. S. sprayed more the CDC would minimize any ..
flndlng^wWcnf^niuld^tte^
ffAgefir'Orange'16nvafci;area ^ Vietnam service to health

•" '

'

'

'

'

'

problems. Levels of combat
were not analyzed, nor were
other studies which showed
that levels of combat had a
great deal to do with health
problems of Vietnam veterans looked at. "It seems that
every time the CDC came up
with a positive finding, it
was interpreted to be either
negative or wrong," Sommer told the committee.
The CDC also failed to
avail itself of the compre;
hensive computer analysis
.of Vietnam service and
•where troops were during
different periods. He said
that the data, developed by
the U.S. Army and Joint Services Environmental Support Group, is one of the
most carefully developed
and extensive records of any
environmental exposure to
be found anywhere. He
chastised the CDC for opting
for a simplistic approach,
rather than using this vital
and readily available tool

Despite Congressional
mandates calling on the Veterans Administration to pay
a certain amount for certain
diseases, not one Agent
Orange claim has yet to be
paid. The VA also denied a
presumption for certain
problems to be related to
dioxin exposure, denying
even more veterans the right
to collect disability compensation.
Sommer's testimony also
endorsed a legislative initiative which would exclude
payments made to veterans
and their survivors under
the Agent Orange liability
settlement In 1984 from
being counted as income
when determining eligibility
for or entitlement to a veteran's or survivor's pension or
a veteran's medical care
under means test provisions.
He also called for the bill to
be extended beyond VA programs, to include any.
based government ass
tance program. •

�Declassified

War

Documents Disclose A/O Use
Counterproductive And Ineffective
By Anthony L. Kimery

I

has been nearly 20 yean since the last orangetripcd, 55-gallon drum of Agent Orange was
prayed on the green canopy of Southeast Asia.
Since that time, the debate about its use and lethal side
effects has appeared steadily throughout what are now
yellowing pages of newsprint, scientific journals, congressional hearings, and scholarly attempts to relate
' 'the history of its use. abuse, and deadly, devastating
consequences. Yet, after all that, there is still another
story to be told. It is the story about the internal policies, politics, and decision-making regarding the use
of chemical defoliants in Southeast Asia. The story is
based on reams of newly declassified military
records that -were recently released by the Army for
' storage at'the National Records and Archives Center
near Washington. DC.
This reporter spent weeks examining these records,
most of which were declassified for the first time since
being turned over to the National Archives. The documents show that America's use of defoliants in South
Vietnam—a program that would be expanded to include Laos and Cambodia in direct violation of MACV
directives governing the use of herbicides—was a holly debated and often strongly contested concept among
military and political planners, strategists, and analysts.
Agent Orange and its chemical cousin. Agent
White, were first introduced to South Vietnam in 1962,
albeit in limited quantities. According to the documents turned over by the Army to the National Archives, the defoliants were earmarked for three broad
purposes. First, they offered a means to destroy crops
and therefore deny foodstuffs to the burgeoning Vietcong movement in the coumryside';"second, they
offered a means to dampen infiltration by providing
observation corridors to South Vietmunete aerial spotters; and third, they offered support for allied
operations—by clearing out landing zones and firebases. Between its introduction in 1962 and the end of
the program in the early I970's, the U.S. government
dumped 20 to 40 million gallons of the chemical on
Southeast Asia, according to the documents. Exact
figures are hard to come by, in apparent reflection of
the willy-nilly planning of the U.S. program.
While actual day-to-day chemical operations were
under the titular control of the South Vietnamese government, it's clear the U.S. initialed and monitored the
program's effectiveness.
Contrary to popular belief, the most healed debates
about the use of defoliants were not over the dangers
they posed to human health, but over whether the
principal reasons for their being used were justified.
The Archives' records indicate that the military has long
been aware that the saturation of South Vietnam widi

herbicides was actually causing more problems than it
was solving.
The declassified records show that the horrific aftermath of Ranch Hand should have been avoided on the
grounds that the program was counterproductive with
respect to the objectives it hoped to achieve. Yet it was
allowed to continue. The documents also indicate that
within just a few years of their introduction to Vietnam, and continuing through the early I970's, there
was overwhelming evidence that the use of defoliants
was not hindering the VC by depriving them of foodstuffs.
A study conducted on the use of herbicides between
1%) and June 1967, for instance, found that there had
been nd effects of any significance from the use of the
herbicides. The study concluded that their use was
instead causing damage with respect to winning the
hearts and minds of the Vietnamese.
This report, and many others, clearly pointed to the
negligible benefits of the further use of defoliants. A
major policy review was convened in 1968 which,
while conceding that the risks of using the defoliants
did not outweigh the benefits, concluded that defoliation efforts should be intensified. As a result of this
study, a clause was built into subsequent directives for
using herbicides to permit their use in heavily populated areas, "in those cases of extreme military
necessity." More important stilt, the military documents show that economic considerations brought
about by the government's murd-million-dollar commitment to bringing on-line a government-run Agent
Orange production plant was an important factor in
escalating defoliation efforts.

I

n late 1967, prior to the broad-based policy review
on the use of defoliants in South Vietnam, the
American military command in South Vietnam
prepared a memorandum containing harsh language
about the "disadvantages" of using herbicides. "The
herbicide program carries with it the potential for causing serious adverse impacts on the economic, social,
and psychological .fields." the report concluded.
Nevertheless, the proponents of Agent Orange within
MACV continued to push for expanded use of Agent
Orange and other herbicides. Consequently, the debate
about their use continued to be rigorously fought in
Saigon, despite doubts about the herbicides' actual
effectiveness.
Probably no better illustration of the conflict within
the military over the use of herbicides is a July 1967
MACV memorandum setting forth new criteria for
defoliant use. "Crop destruction should continue to be
the highest priority for the use of herbicides." (he

memorandum states. It adds, "there has never been a
question as to the effectiveness of crop destruction."
This conclusion, however, is in glaring contrast to
what militarily contracted studies and intelligence reports were showing. A RAND Corporation report concluded in October 1967 that the VC required only three
percent of the total food consumed in the country, that
the crop-destruction operations were not in any major
sense denying food to the VC, and that Vietnamese
peasants, the target of long-range pacification objectives, bore (he brunt of the crop-destruction efforts,
and they held the U.S. and the Government of
Sourh Vietnam (GVN) responsible.
As of July 31, 1968. the VCand North Vietnamese
Army (NVA) had a daily food requirement of about
215 short ions, according to the documents. About 58
percent, or 124 short tons, could be internally procured
in South Vietnam. Of that, "only a small portion is
produced by the enemy in areas subject to herbicide
operations," a MACV report concluded. This report
added that "food shortages are reported in captured
documents, but they are temporary in nature and are
often the result of distribution problems. The enemy
usually meets the minimum food requirements of his
military forces."
Numerous internal MACV reports, memorandums,
and intelligence briefs support these conclusions. A
1968 MACV report on the RAND and other studies
states, "reported food shortages have been the result of
Allied sweep operations, not of herbicide operations.''
This had already been spelled out earlier, in a December 1967 field report to MACV, which states, "this
headquarters does not have empirical data on the
effects of herbicide operations on VC/NVA food
stocks, nor is there evidence that enemy combat operations have been cancelled because of food shortages
resulting from crop destruction. Such food shortages as
Continued on next page
Above: Three Air Force C-I.Ws spray Orange in
the A Shau. Right: A USAF airman operates spray
equipment during defoliation mission

NOVEMBnR/OECF.MRF.R |0«»

�are known (o exist among the VC arc the results of a
many-faceted program to deny resources to the
enemy." The report went on to stale that "the effort
and cost of employing crop destruction is insignificant
in comparison to (he troop effort required to control
and secure an equivalent area of rice."
(n a 1968 MACV evaluation of crop-destruction
programs which followed the final 1%8 herbicide policy review, Col. John Moran, chief of the Chemical
Operations Division, slated (hat "herbicide crop destruction is only one aspect of a comprehensive fooddenial program." Moran went on to stale that deprivation of food is due more to "Allied sweep operations"
and only "occasionally to herbicide operations."
The 196)1 MACV evaluation also emphasizes, as did
the contracted private studies, (hat "very few POWs
who have infiltrated ever mention the efforts of U.S.
herbicide operations. Some stale (hat they have seen
areas where vegetation has been killed but do not
mention any infiltration problems caused by (he defoliation. There are indications that U.S. herbicide
operations have had a negligible effect on NVA infiltration and combat operations."
Yet, while this report says, "herbicide operations
. . . appear to cause temporary food shortages in the
area defoliated, but have little lasting effect on
the VONVA food supply." it nevertheless states, "the
CINCPAC Scientific Advisory Group concludes,
without qualification, (hat the crop-destruction program is an essential and effective part of the total effort
in South Vietnam."
If there was ever any doubt about the ineffectiveness
of U.S. defoliation operations, however, they were put
firmly to rest in a MACV briefing paper dated December 1967. "Within the context of what has been studied, it would appear the crop-destruction effort may
well be counterproductive. The VC continue to feed
themselves, while the peasant bears the brunt_of the

deprivation and doesn't like it." In other words, the
U.S. policy of spraying Agent Orange over wide areas
of South Vietnam in order to deny the VC and NVA the
use of cover and food resources was not only not
working and unnecessary, it was actually harming the
American war effort.
ile it was agreed by military planners in
Saigon that the use of herbicides was sucT T cessful in denying the enemy cover, there is
abundant evidence that defoliants did not significantly
deprive the Vietcong access to food stores. One of the
most damning condemnations of the use of herbicides
found in the National Archives came in a November
20. 1968. letter from Robert II. Marian, USAID assistant director for economic planning and policy and
embassy counselor for economic affaire to U.S. ambassador Ellsworth Bunker.
Marian protested the expanding use of defoliants in
Quang Due and Phu Bon Provinces. "I feel compelled
to nonconcur in both proposals," Harlan wrote.
"Although crop destruction operations may have had
some successes, we suspect their effectiveness in hampering enemy military operations may have been exaggerated. The Report of the Herbicide Policy Review
Committee, itself, on Page 17 pointed out, 'herbicide
crop destruction is only one aspect of the efforts to
deny foodstuffs to the VONVA. The enemy relies on
commercial purchases, imports, taxation, requisition,
and confiscation for some 90 percent of his food
requirement.' "
The negligible contribution!! of herbicide operations
were equally evident with respect to the effect that
herbicide operations were having on the Vietnamese
population. In the early !960's. a herbicide evaluation
report noted, "the chief sufferer from crop-destruction
operations is the local worker." Such findings con-

At right: USAF sprayers in stables in South Vietnam; they
called for thousands of gallons. Below: Loading White on
an Irotjuois prior to defoliation mission. U.S. dispatched
special chemical teams

VETERAN

tinued (o mount through the balance of the 1960's and
up until (he 1968 policy review.
The same inconsistencies found in the debate about
the effectiveness of denying food to the VONVA were
just as replete in the debate over the psychological
effects (he defoliants were supposed to bring. One
MACV report. Advantages and Disadvantages of the
Use of Herhicides in Vietnam, states, "the herbicide
program dues not loom large as a public-opinion issue
at the present lime." At the same lime, a MACCORDS evaluation report was staling that "the herbicide program is one of the most widely known programs" among the population, and it "is a natural
topic of interest with people whose livelihood is in the
land."
"The principal effect on pacification is the animosity the peasant feels initially towards the U.S. for being
responsible for the damage," the MAC-CORDS evaluation says, "and then toward the GVN for its failure
to rectify the situation. There is nothing that can be
done beforehand lo head off the alienation the peasant
develops when his crops are destroyed." The MACCORDS report then summarizes the inadequacy of
South Vietnam government efforts to compensate antiVC peasants for the inadvertent loss of their crops.
"The present system is completely unsatisfactory
from the point of view of rectifying the economic
damage and its psychological impact by demonstrating
lo the peasant the concern of the government for his
welfare," (he report states.
"The slowness and unfairness of this system usually
result in further alienation of the peasant. He is left to
his own devices to find the means with which to replant
his crop, if there is enough time left in the growing
season, or lo find some other means of supporting his
family. Even if his claim were approved, the time lapse
between submission and payment and the fact that it
represents only a fraction of the actual damage, have
the result of leaving the peasant in the hole and bearing
the responsibility for an act he was helpless to prevent.
As long as the present system remains, the pacification
program is going lo suffer unpredictable .setbacks
which h is at present unable to alleviate wnh-^ny—'
effectiveness . . . The net effect is to alienate him
further from his government.
The report's conclusion seems to indicate that the
spraying of Agent Orange was having more than just a
slight impact on VC and NVA resources—it was
actually turning pro-government peasants into antigovernment guerrillas.
Col. Moran's report corroborates the MAC-CORDS
evaluation. "The vast majority of (he enemy's daily
food requirement is procured through taxation of the
people and purchases from the local markets," Moran
wrote. "While the enemy's production capability has
been reduced, his procurement efforts have enabled
him to sustain his forces. The taxes levied on the
people arc in the form of food, money, and services.
Through these measure!!, the enemy has been able (o.
procure enough food from outside his areas to nearly
offset his production losses.
"The obvious reaction of the peasant whose labors
have been destroyed is one of bitterness and haired. He
will frequently direct this hatred toward the U.SXJVN
for accomplishing the destruction. If he has previously
leaned toward the VC, he is likely to side with them
completely after the crop destruction.
"Captured documents and interrogation reports
indicate that the detrimental effects of herbicide operations far outweigh the beneficial effects." Moran
concludes. "Civilians living in VONVA-conlrolled
areas, whose crops are destroyed by herbicide operations, have no recourse but lo face famine and
possible starvation as a result of Allied destruction of
their crops."
The declassified documents clearly present a picture
which shows that the U.S.'s defoliation program nullified pacification efforts by alienating the Vietnamese
from not only the U.S.. but from their own government
as well. By the time the defoliation operations were
stopped, the damage was irreparable. The documents
also show that in other areas, the U.S. defoliation
campaign was counterproductive to the U.S. war
effort. The records show, for instance, that the destruction of valuable resources, such as harvestable limber
and rubber trees, was far greater than was reported or
admitted by the U.S. during (he war.

�s public concerns over the use of herbicides
intensified, the need for a policy was quickly
L recognized and embarked upon by (he U.S. It
is clear from (he minutes of those meetings (hat the
intent was to allay fears by not only continuing defoliation efforts, hut by expanding them.
The first meeting on this subject took place on January 17, 1968. under (he chairmanship of David
Carpenter, political officer at the U.S. embassy. In a
memorandum for the record distributed (he following
day by Col. Morin. he stresses thai Carpenter
"emphasized that if (here should be a leak of this
information to the press, (he embassy would receive
m a n y inquiries which would be d i f f i c u l t to
respond to."
Not only was the embassy keeping the true intent
and purpose of the policy review from the press, it was
also keeping it secret from the GVN. "Mr. Carpenter
cautioned the members of the committee that there
should he no release of the purpose and actions of the
committee (o the Republic of Vietnam," Moran wrote.
' 'There may be a need to call on officials of the Republic of Vietnam for certain data; however, such contacts
should be limited to (he specific subject area involved
without divulging any information of the policy review. He further requested that contacts with the Vietnamese government concerning these matters be conducted with his office."
Such secrecy contrasted with the U.S.'s repeated
assertion (hat herbicide operations were strictly under
the control of (he GVN. with (he U.S. providing only
support and logistic roles. This was again reiterated at a
September 20.l%8. background briefing for the press
in Saigon following the policy review.
The answers provided to questions raised by the
press during the briefing glaringly contradict information about the negligible effects of the defoliation programs. A memorandum to the secretary of stale from
Ambassador Bunker, drafted the week before the press
briefing, establishes that the press, public, and even

l*eft: Dr. James flrwn
inspects results tif
defoliant sprayin/t.
Below: Ranch hands
inspert chemical
Murage tank onboard
U.S. aircraft

In secret briefing papers prepared during late 1967, imum use of Orange."
at a time when the Department of Defense was purling
Another memorandum emphasizes the nerd to use
into motion an Agent Orange expansion program, it is ' 'Orange in lieu of White (o avoid further procurement
evident that orders for Agent Orange had consistently of White.'' Contracts for Agent Orange were having (o
far exceeded both the ability and capability for using be "terminated at msts in excess of 1.5 million dolthis herbicide, which had caused an enormous lars." with "ultimate" contract terminations costing
surplus—a surplus that was only going to get worse ihe government $19.1 million—a reflection of the US
with a new multi-million dollar, government-run government's inability lo draw-down the Agent
Agent Orange production plant soon to come on-line as Orange surplus.
a result of the expansion program.
' 'Considerable dollar savings may he expected from
One of the conclusions of these briefing papers, acceptable and maximum use of Orange." another
which helped to prepare the way for the pending policy memorandum stales. "Forestalling potential future
review, was that "MACV could be embarrassed if criticism of herbicide procurements should result if
[the) plant expansion is carried out, and the pro- Orange can be employed to a greater extent*... regrammed herbicide cannot be used."
quest review of requirements for both Orange and
A report prepared by USAF Col. H.F. Greenhow, White herbicides and recommendations concerning
Material Division, put the economic reasons for un- possible means to increase substitution of Orange for
precedented increase in the use of Agent Orange vivid- While."
ly in focus: "In view of the large inventory on hand,
Memorandum after memorandum reiterates Ihe sur(he huge investment in production capability, and the plus problem. "White is being consumed at higher
future low cost of Orange, it is imperative from an than forecast rates and is in short supply, while Orange
economic point of view (hat Orange be used to the is heavily overstocked." one report notes. "Every
maximum extent possible and that White be used only effort must be made lo schedule herbicide operations in
when there is a compelling operational requirement." such a manner that White will not be used in lieu of
Greenhow stressed that "the MACV staff computing Orange." another report says.
requirements need to be more accurate in (heir com"Considerations argue strongly for use of Orange,
putations and project their requirements into the future which is overstocked." wrote Army deputy assistant
and realize die dollar impact caused by changes in chief of staff. MACV. Brigadier General John G.
requirements."
Wheelock. 111.
By the time Greenhow prepared his report, howevFinally, on April 14. 1969, the U.S. embassy suser, MACVs "overstatement of requirements" had pended its policy requiring the use of Agent Orange on
caused "excess quantities (of Agent Orange) having certain restricted defoliation targets, such as rubber
been purchased." resulting in an 18-month supply on plantations and other valuable natural resources, and
hand in (he system, with an additional eight million allowed the "use of Orange herbicide on all defoliation
gallons per year to begin being produced in December targets." adding, "for economic reasons, the use of
1969 by the government's facility.
Orange is preferred."
The pressure was on. Twenty-eight million gallons
had been committed for the completion of this plant,
located at Weklon Springs. Missouri, as a result of the .
hen concerns about the dangers dioxin
deputy secretary of defense having, on erroneous information, ordered an Agent Orange expansion proposed to human health began to explode
gram on July 31, 1967, an order that came at a time
seven months later, in late 1969. there was
when MACV was well aware that the use of Agent still little attention paid to Ihe ramifications of the allOrange was far less than it was forecasting, or had the out effort to deplete Agent Orange stockpiles. A memcapability to use. It was also at a time when the MACV orandum from the deputy secretary of defense to the
the GVN. were being deliberately deceived about the secret briefing papers were pointing out that chairman of (he Joint Chiefs of Staff sent lo CINCPAC
"MACV could be embarrassed if plant expansion is carried concludes that "large-scale substitution for Orange
consequences of herbicide operations.
will not be permitted."
"We would prefer not to draw attention, even by out. and the programmed herbicide cannot be teed."
By early 1969. the problem with the surplus of
Despite (he fact that the memorandum points out
implication, to the serious shortcomings (he |policy|
review revealed in (he aspects of (he |hertncide| pro- Agent Orange was embarrassingly out of hand. Com- (even at this early lime) that the National Institutes of
grams." Bunker said.
munications traffic during this time period was frenetic Health had presented evidence that 2.4.5-T "can cause
Among the shortcomings (hat were being concealed with requests and discussions about reducing the sur- malformation of offsprings and stillbirths in mice,
was the growing concern over the economics of too plus of Agent Orange. Asa result. Agent Orange began when given in relatively high doses." and that "this
much Agent Orange having been procured. By (his to be used for every defoliation purpose. The use of all material is present in defoliant Orange." Ihe largetime, "the entire commercial production of Orange other herbicides was brought to an abrupt halt, while a scale, and apparently counterproductive, spraying of
(had been | diverted from domestic use to military re- number of policies governing the use of defoliants the chemical went forward.
.quirements in Southeast Asia."
were relaxed in order to deplete (he Agent Orange
Within a few years, though, (he outrage over using
Throughout the late I960'], beginning in 1967. surplus.
chemical defoliants had grown so intense, both back
Since "Agent Orange stocks were in long supply, home and in (he world community, that Ihe U.S. was
military records declassified for the Veteran began to
reflect that (here were pressing economic reasons and costly contract terminations were involved," one forced lo cancel its defoliation operations. But. by that
favoring (he apparent unjustified reason (o increase the memorandum states in communications used in the time, following a decade of having negligently satuse of defoliants, especially Agent Orange, which had decision to halt the use of other defoliants, the termina- urated Southeast Asia with the chemical, the damage
wrongly been ordered in vast quantities because of a tion of the use of other herbicides "should result in had already been done by a program, Ihe objectives of
considerable dollar savings from acceptance and max- which all along were not being achieved."
domestic shortage.

W

NOVF.MBF.R/DF.CEMBKR I

17

�Congreste of tfje ®mteb
JB.C. 20510

November 22, 1988

Honorable Donald M. Newman
Chairman
Agent Orange Working Group
200 Independence Avenue, S.W.
Washington, D.C. 20201
Dear Don,
As Chairmen and Ranking Minority Members of the House and Senate
Veterans' Affairs Committees, we are writing to request that the
Agent Orange Working Group review and provide comments on five
studies recently published in "Environmental Research." (A copy of
the journal is enclosed.) The studies examine the health effects of
herbicide exposure and service in Vietnam based on questionnaires
completed by American Legion members. We would appreciate your
comments with respect to the scientific methods used, the validity
of the statistical analyses, and the strength of the studies'
findings.
As always, we appreciate your continuing cooperation and support.
We look forward to your response.
With warm regards,
Cordially,

^-»-A^ruc&lt;i
G.V. (Sonny) Montgomery
Chairman
' &lt;j y i f 1

ans't'on
Chairman

Solomon
nority Member

Frank H. Murkowski
Ranking Minority Member
Senate Committee on
Veterans' Affairs

,„/,„/„

BZ AOW e&lt;?
Q3A

House/Committee on
Vete/ans1 Affairs

�NATIONAL VIETNAM VETERANS COALITION
1000 Thomas Jefferson St.. Sixlh Floor
Washington. D.C. 20007
(202) 338 NVVC
J. IVmu* Hnrrh. Jr.

November 1988

.

No. 48

AGENT ORANGE
Pending New Legislation
The omnibus veterans benefits legislation
following new provisions on Agent Orange:

contains

the

(T)his agreement (i.e. the bill) would extend, from
September 30, 1989 to December 31, 1990, the authority to provide
basic VA health-care services for veterans' disabilities if it is
found that the veteran, during active duty, may have been exposed
in Vietnam to
any toxic substance
in a herbicide
or
defoliant. . . .
(T)he agreement also includes a provision that states that
amounts received as part of the settlement of the agent orange
product liability litigation will not be considered as income for
purposes of any of the needs-based programs administer by the VA,
including nonservice-connected VA pension.
(T)he proposed amendments would require the VA to conduct an
outreach program to Vietnam veterans oriented to notifying them
of health risks, if any, resulting from exposure to herbicides in

- 13 -

�Vietnam, as information on such health risks becomes known. In
order to facilitate such an outreach effort, the bill would
require the VA to take reasonable actions to organize and update
the information contained in the VA's agent orange registry,
particularly the addresses of veterans listed in the registry.
(Remarks by Rep. G.V. (Sonny) Montgomery, Congressional Record,
Oct. 19, 1988, H10353.)
The committee report accompanying the legislation includes
the following comments:
Section 1203 of the bill treats Agent Orange payments "as
reimbursement
for
prior
unreimbursed
medical
expenses."
(Id., H10338, 10555) (Ed. Note: The bill, however, does not make
a similar exception for Social Security disability pensions or
food stamp eligibility.) . . . .
&gt;
After February 28, 1989, not less than one-third of the
total number of members of the Ranch Hand Advisory Committee
shall be individuals selected by the Secretary of Health and
Human Services from among scientists who are recommended by
veterans' organizations . . . . (Id., H10334, H10339)
The House . . . rejected a Senate bill that, for the first
time, would award disability benefits to veterans exposed to
Agenent Orange during the Vietnam War [i.e., for soft tissue
sarcoma, no-Hodgkins lymphoma]
(Rep. Sonny) Montgomery said
further studies were needed to prove a connection between various
diseases and Agent Organge.
(Philadelphia Inquierer, Oct. 20,
1988)
"Sprayed and Betrayed" - Round II
More newly declassified documents emerge from the National
Archives:
The State Department was involved in policy-making re
spraying operations.
"On 14 April 1969, the U.S. Embassy
suspended its policy requiring the use of WHITE herbicide on
certain restricted defoliation targets and will now allow use of
ORANGE herbicide in all defoliation targets.
For economic
reasons, tfie use of ORANGE is preferred . . . . We respectfully
request that you assure WHITE stocks are kept available for use
should the policy be deinstituted."
(Memorandum for Col. Tran
Dinh Tho from Col. Harold C. Kerne (?) , Jr., "Use of Defoliants
ORANGE and WHITE (V), 17 April 1969).
LTC John A. Sullivan,
CONVSNACV notes in a memo to CINCPAC "Ambassador Sullivan's
approval has been requested for the use of CS in those areas of
Laos approved for spray operations.
("Use of Riot Control Agent
CS," undated)
MIAs.
During the week ending 4 Feb. 67, the following
defoliation missions were flown in Laos with C-123 aircraft:

- 14 -

�31 Jan 3 sorties . . . Acft 611 lost to ground fire. 5 KIA
(Ed. Note: the five men are now on the MIA list) (Memorandum
from Maj. Philip L. Boster, COMUSMACV to NMCC, "Herbicide Report
(V)," undated. Access Number (?) 0380818)
The Empty Drums. The New Jersey Agent Orange Commission
interprets other reports:
•
"It seems that as far as the US Government was concerned,
"empty" Agent Orange drums were the property of the,, ARVN, and
they could dispose of then anyway they chose. The problem was
the drums weren't really empty, and each contained about 2.2
gallons of Agent Orange that was not pumped o,ut. The ARVN, in
their constant quest to turn an extra buck, sold the drums to
anyone who wanted them, generally civilians for about $2 each.
The creative Vietnamese civilians used them for all sorts of
things, spilling the residual Agent Orange all over the place and
seriously damaging plants and shade trees throughout the city of
Danang. The defoliant was even killing the civilians' vegetable
gardens.
Since we were using about 1000 gallns per day of
herbicide out of Danang at the time, about 20 "empty" drums of
Agent Orange were hitting the streets of Danang every day!! to
compound this lunacy even more, it seems that the Vietnamese Navy
compound purchased some of the drums to store gasoline for their
generators.
The result is that they ended up fogging their
entire compound through the generator exhaust with Agent Orange,
effectively killing all vegetation in sight!!
"The report recommended that the practice of allowing the
ARVN to sell the drums be discontinued, but we're not sure that
ever happened. It also should be mentioned that Agent Orange was
also stored at Bien Hoa, Phu Cat, Nha Trang, and in Saigon and
was presumably disposed in the same manner."
(NJAOC, Agent
Orange Update, Oct. 1988)
Miscellaneous
1.
From studying the injuries among the tens of thousands
of Kurdish refugees, the doctors believe the Iraquis are using a
mixture of herbicide and a form of tear gas known as CS to drive
the Kurds from their mountain villages.
(Edmonton Journal, (?)
Sept. 21, 1988)
2.
(Vietnam veteran Ron Heiman) was 38 years
died in January of this year . . . . The doctor put
of death, on his death certificate, the type of
killed him, and added that it was a direct result of
poisoning. This is the first time such a statement
an official record.

old when he
as the cause
cancer that
Agent Orange
appeared in

Well, the Death Certificate on file at the County Medical
examiner's office has been changed!
Any reference to Agent

- 15 -

�Orange has been removed from the official files!
letter from George L. Claxton, Oct. 19, 1988)

(Attachment to

3.
Was the morbidity of women Vietnam-era veterans
affected by assignment in Vietnam? . . .
(N)o remarkable
differences
(between
a control group
of
720 U.S.-based
Vietnam-era veterans and a study group of 28 Vietnam veterans)
are seen in the percentage of those who had an acute illness, GYN
condition or miscarriage.
However, three interesting differences are observed. First,
a higher percentage of those who were assigned in Vietnam have
chronic conditions and disabilities, and they have more of them.
Second, a higher percentage have been told they have cancer.
Third, although a smaller percentage of Vietnam-assigned women
ever had a baby, a higher percentage of those who did have
children born with defects and/or die before their first
birthday.
(Le Donne, Trends in Morbidity and Use of Health
Services by Women Veterans of Vietnam, Navy Medicine. May-June
1988, p. 24)
4.
What's Evidence?, by Joe Cole (Mahess Productions, Inc.
states: "blows the lid off") Send $15.00 to Joe Cole, 6806 36th
Ave., S.E., Olympia, Washington 98503
5.
As part of a budget austerity program in Massachusetts,
the state's funding of its prestigious Agent Orange Commission
has been reportedly "substantially reduced."
6.
The Washington (Me) Sunrise Memorial; Made of two
large, rugged stones, standing like the tattered pages of an open
boo, the memorial carries three messages: one for those who are
still missing in action or prisoners of war; one for all the men
and women who served in Southeast Asia; and one for the veterans
who have died, and the veterans and their families who continue
to suffer, from medical and psychological problems associated
with exposure to the chemical defoliants, such as Agent Orange,
used in the war. (Bangor Daily News, Oct. 24, 1 9 8 8 ) ( E d . N o t e :
This is claimed to be the first memorial in the country to honor
Agent Orange victims .
J

•-14 -

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&lt;p&gt;For more about this collection, &lt;a href="/exhibits/speccoll/exhibits/show/alvin-l--young-collection-on-a"&gt;view the Agent Orange Exhibit.&lt;/a&gt;&lt;/p&gt;</text>
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&lt;p&gt;For more about this collection, &lt;a href="/exhibits/speccoll/exhibits/show/alvin-l--young-collection-on-a"&gt;view the Agent Orange Exhibit.&lt;/a&gt;&lt;/p&gt;</text>
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&lt;p&gt;For more about this collection, &lt;a href="/exhibits/speccoll/exhibits/show/alvin-l--young-collection-on-a"&gt;view the Agent Orange Exhibit.&lt;/a&gt;&lt;/p&gt;</text>
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                    <text>Item ID Number

01336

Author

Smith, Pamela W.

Corporate Author

Science Policy Research Division, Library of Congress,

Report/Article TitlO Agent Orange: Veterans' Complaints Concerning
Exposure to Herbicides in South Vietnam, Issue Brief
Number IB80040

Journal/Book Title
Year

1982

Month/Day

APHI 20

Color

n

Number of Images
DeSOriptOU Notes

21

Date

originated: 09/06/79, Date Updated: 04/20/82.
Includes a table of military projects involving agents
orange, purple, pink, or green, with dates and
descriptions of projects. Also includes a table of the
signs, symptoms, and disorders reported after
occupational exposure to TCP, 2,4,5-T or TCDD. Item
gives an overview of background and policy analysis,
health effects, perseonnel exposure, veterans'
problems, Department of Defense efforts, health
studies, the Interagency Work Group and Agent Orange
Working Group, Congressional action, and legislation
and hearings

Thursday, May 03, 2001

Page 1336 of 1403

�AGENT ORANGE:

VETERANS' COMPLAINTS CONCERNING EXPOSURE
TO HERBICIDES IN SOUTH VIETNAM
ISSUE BRIEF NUMBER IB80040

AUTHOR:
Pamela W. Smith
Science Policy Research Division

THE LIBRARY OF CONGRESS
CONGRESSIONAL RESEARCH SERVICE
MAJOR ISSUES SYSTEM

DATE ORIGINATED 09/06/79
DATE UPDATED 04/20/82

FOR ADDITIONAL INFORMATION CALL 287-5700
0426

�CRS- 1

IB80040

UPDATE-04/20/82

ISSUE DEFINITION
From 1962 to 1971, the United States Air Force
(USAF) sprayed various
herbicide mixtures (chemicals that kill plants) in South Vietnam.
The
purpose of the spraying was to defoliate jungle growth to deprive the
Communist forces of ground cover, and to destroy enemy crops to restrict food
supplies. The most extensively used of these herbicide mixtures was known as
Agent Orange, a 50:50 mix of two common herbicides called 2,4,5-T and 2,4-D
(2,4,5-trichlorophenoxyacetic' acid and 2,4-dichlorophenoxyacetic acid).
A
third chemical present in the mixture in small amounts was TCDD, an
inevitable by-product of the manufacture of 2,4,5-T. This chemical, called
tetrachlorodibenzo-para-dioxin or simply "dioxin," is highly toxic
to
laboratory animals when administered in its pure form.
Acute
(short-term)
toxicity values in humans have not been established, although Gosselin et
al., in the 1976 edition of Clinical Toxicology of Commercial Products, puts
TCDD in a class of chemicals for which the "probable lethal dose" for humans
would be less than 5 mg/kg, or about 7 drops for a 150 Ib (70 kg) person.
CRS has been unable to locate any report of a human death from exposure to
pure TCDD.
The human health effect that has been most consistently
documented following exposure to small amounts of TCDD as a contaminant in
other compounds is a skin condition known as chloracne. There is other, less
consistent, evidence of damage to the liver and the nervous system in humans.
Extensive testing on laboratory animals has been done to determine possible
long-term effects of exposure to TCDD.
It can induce cancer in some strains
of rats and mice (carcinogenicity) , cause fetal death in several
species
(fetotoxicity)
and
birth
defects
in
developing
mouse
fetuses
(teratogenicity), but has been found not to cause genetic changes in
mammalian cells (mutagenicity). The American Medical Association's Council
on Scientific Affairs concluded that "there is no scientific evidence that
2,4-D, 2,4,5-T or TCDD has caused reproductive difficulties or hazards in the
human. "
Congressional interest was triggered by receipt of reports from Vietnam
veterans who believed they had been harmed by exposure to herbicides,
particularly Agent Orange. The 96th Congress held numerous hearings on the
use of herbicides in South Vietnam, and various initiatives to deal with the
problem were introduced. P.L. 96-151 was enacted to direct the Veterans
Administration (VA) to conduct an epidemiological study on Vietnam veterans
to determine whether there may be adverse human health effects
associated
with exposure to phenoxy herbicides and/or dioxin.
This study and other
studies planned will help elicit answers to the scientific questions posed by
the Veterans Administration in determining whether or not the veterans'
medical problems, allegedly due to exposure to Agent Orange and
associated
herbicides used in Vietnam, are compensable. Following recommendations made
by the Interagency Work Group on Phenoxy Herbicides
(now the Agent Orange
Working Group), legislation was introduced in the 97th Congress to expand the
scope of the VA's epidemiological study of the health effects of Agent Orange
to include other factors related to military
service in Vietnam.
The
legislation also allows veterans with medically certifiable conditions that
might possibly have been caused by exposure to Agent Orange to receive
medical care in VA facilities.
The bill (H.R. 3499) was considered by the
House and Senate in June 1981, put into final form in October, and signed by
the President Nov. 3, 1981.
Its title is the Veterans' Health Care,
Training, and -Small Business Loan Act of 1981 (P.L. 97-72).

�CRS- 2

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UPDATE-04/20/82

BACKGROUND AND POLICY ANALYSIS
History
During the summer of 1969,
the first reports of human birth defects
allegedly attributed to Agent Orange appeared in Vietnamese newspapers.
Based on these allegations and the results of a study sponsored by the
National Cancer Institute that showed that
2,4,5-T contaminated
with TCDD
caused birth defects in laboratory animals, the USAF stopped spraying 2,4,5-T
in South Vietnam by early 1971.
Although the Department of Defense maintains that only a limited number of
U.S. military personnel can be positively identified as having been exposed
to 2,4,5-T in South Vietnam (i.e., crews of aircraft that were used to spray
herbicides), it is theoretically possible that large numbers of both military
personnel (from the United States, South Vietnam, North Vietnam, Australia,
and New Zealand) and civilians (especially South Vietnamese peasants)
were
exposed to 2,4,5-T through the USAF spraying program. A growing number of
U.S. veterans who served in South Vietnam have begun to attribute the cause
of various chronic ailments which they are now experiencing
(especially
nervous disorders, cancers, and birth defects in their offspring) to exposure
to 2,4,5-T in South Vietnam, and many have filed claims with the VA for
compensation. The VA has not yet awarded compensation to veterans for any
claims related to 2,4,5-T exposure because of the lack of valid human data to
prove a cause and effect relationship between exposure to 2,4,5-T and/or TCDD
and specific health effects (except for chloracne).
TCDD Contamination
The industrial production "of 2,4,5-T always
results in some
TCDD
contamination although TCDD levels can be reduced to about 0.01
parts per
million (ppm) with current technology. Because it was not widely
recognized
until the late 1960s that 2,4,5-T could contain hazardous
amounts of TCDD,
manufacturers did not start reducing the level of TCDD in 2,4,5-T until the
USAF was already winding down its herbicide spraying program.
The average
TCDD levels in the 2,4,5-T - containing
herbicide mixtures used in South
Vietnam were approximately
2 ppm in Agent Orange
(which accounted for
approximately 96% of the 2,4,5-T used in South Vietnam), approximately
32.8
ppm in Agent Purple, and 65.6 ppm in Agents Pink and Green
(Agents Purple,
Pink, and Green contained the remaining 2,4,5-T used in South Vietnam).
The
herbicides procured by the USAF were code named after the colored band that
was placed around each 55 gallon drum in order to identify the contents.
/

Health Effects —

Animal Data

Although TCDD is well established as one of the most toxic chemicals known
for acute (short-term) effects, there is no consensus in the
scientific
community over the -Chronic (long-term) effects on humans of exposure to low
levels of TCDD (such as those levels found in the herbicides used in South
Vietnam) .
Statistically

significant

animal

experiments

have

demonstrated

that

�CRS- 3

IB80040

UPDATE-04/20/82

2,4,5-T containing low levels of TCDD and/or TCDD alone have caused various
tumors in mice and rats. A recently-released National Toxicology Program
bioassay of TCDD confirms these earlier reports that TCDD is carcinogenic in
some laboratory animals. Thymic atrophy (without a corresponding loss in
immune function) and severe weight loss have been observed in many species
after TCDD exposure. In some species, acute exposure to TCDD can cause liver
damage. Birth defects such as cleft palate and kidney abnormalities have
been reported in baby mice when the mothers were exposed during pregnancy. A
National Toxicology Program animal study of male reproductive effects of
exposure to TCDD, however, has failed to reveal a statistically
significant
increase in reproductive abnormalities
in TCDD-exposed animals or birth
defects in the TCDD-exposed male animals' offspring. Although there is some
experimental evidence that TCDD may cause mutations (changes in the cell's
genetic material that may produce birth defects in as-yet-unconceived
offspring), these experiments have been few, they have been done mainly on
non-mammalian species or in vitro (in test tubes), and they have basically
been inconclusive.
Some investigators feel that humans are less sensitive than animals to the
toxic effects of TCDD. There is wide variation of" responses to TCDD among
different species, and the mechanisms of its toxicity and metabolism are not
understood. More work needs to be done to clarify whether human exposure to
TCDD can produce the same health effects with the same potency as those
observed in animal studies.
Health Effects. -- Human.TData.
If a cause and effect relationship is to be scientifically
established
between human exposure to a chemical and chronic health effects, a study
which meets the following minimum criteria must be conducted to prove that
such a relationship exists: a group of people (the "study group") must be
identified that has already been exposed to the chemical under study (it
would help to know the level of exposure); this study group must be large
enough to detect chronic effects with statistical significance
(to find an
effect that occurred in 1 out of 100 people, one would need to examine at
least 100 people); a control group must be found that ideally would differ
from the study group only by never having been exposed to the chemical under
study (thus, any differences in chronic health effects between the study and
control groups could be attributed only to exposure to the chemical under
study); and, due to the long latency period for many chronic effects, the
study and control groups must be followed for as many years after exposure as
it takes for the chronic effects to show up
(i.e., in
carcinogenicity
studies, subjects must be followed for a minimum of 10 to 20 years after
exposure to the suspect carcinogen). These exacting criteria are not met by
most of the studies that have explored the relationship
between human
exposure to TCDD and/or 2,4,5,-T and subsequent health effects.
Only for
chloracne has such a cause and effect relationship been well established.
Workers who have been exposed to TCDD and/or
2,4,5-T in industrial
explosions or who have had other occupational exposure are frequently found
to have a skin condition known as chloracne — which resembles normal acne
except that it is caused by chemical exposure.
Chloracne can appear from
weeks to months after initial exposure and while mild cases (blackheads)
may
clear in a matter of months, severe cases (inflammatory lesions and
scars)
may last up to 30 years after exposure has ceased.
While the severity of
chloracne is not thought to correlate precisely with the intensity or
duration of exposure to TCDD and/or
2,4,5-T, chloracne is associated
so

�CRS- 4

IB80040

UPDATE-04/2'0/82

closely with exposure that some scientists argue that patients who have not
exhibited chloracne are unlikely to have suffered other toxic effects of TCDD
and/or 2,4,5-T exposure.
Studies of these exposed workers have also indicated a variety of other
health problems. For example, the United States Air Force Technical Report
on the Toxicology, Environmental Fate, and Human Risk of Herbicide Orange and
its associated Dioxin (1978) listed a number of symptoms, signs, or disorders
that had been reported after occupational exposure to TCP
(trichlorophenol,
2,4,5-T's precursor), 2,4,5-T, or TCDD
(see Appendix).
As noted, these
studies, which reported symptoms associated with human exposure to dioxin,
were not conducted in such a way as to prove a cause-and-effect relationship
between exposure to TCDD and/or 2,4,5-T and any of these effects, but they
may be indicative of such a relationship.
Several of the above studies have focused on investigating
cancer
rates
among exposed workers. These studies do not show a clear
cause/effect
relationship between carcinogenicity associated with exposure to TCDD
and/or
2,4,5-T because very few exposed workers (with the exception
of those in
Nitro, West Virginia) have been followed for more than ten years (the latency
period for most cancers being 15 to 40 years after exposure) and the results
have been equivocal.
However, they support a continuing suspicion and
indicate a need for further study.
When the scientific
panel of the
Interagency Work Group on Phenoxy Herbicides reviewed five research papers by
European scientists, it concluded that despite the studies' limitations, they
do "show a correlation between exposure to phenoxy acid herbicides and an
increased risk of some forms of cancer." A soft-tissue "sarcoma study has
been proposed that will be conducted jointly by the Armed Forces Institute of
Pathology and the National Cancer Institute.
Studies that have been conducted in non-industrial settings have not been
able to prove a cause and effect relationship between exposure to TCDD and/or
2,4,5-T and specific health effects. The National Academy of Sciences
(NAS)
was directed by Congress P.L. 91-441, sec. 506 (c) to conduct a study on the
effects of herbicides in South Vietnam, including health effects.
This NAS
study, as well as at least three other similar studies that were conducted in
South Vietnam during the early 1970s, were unable to find adequate data upon
which to reach any conclusions concerning a causal effect between exposure to
herbicides and any health effects, including birth defects.
An explosion in a Hoffman-LaRoche chemical plant in Seveso, Italy in July
1976 caused thousands of people to be exposed to varying doses of TCDD as a
toxic cloud drifted across the Italian countryside in a cone-shaped pattern
about a mile long and half a mile wide. Some 5400 people lived in the two
zones most directly affected, with an additional
40,000 people
potentially
exposed. Animals began to die 2 to 3 days after the incident with over 1,100
animals killed by direct exposure to TCDD. Over 700 people were
evacuated
from their homes. Chloracne was reported in 187 people, mostly children, and
it tended to heal rapidly. Long-term human health effects of exposure to
TCDD at Seveso are still being studied.
Preliminary
findings reported in
1979 by Hoffman-LaRoche revealed that Seveso residents had suffered liver
damage but that there was no permanent breakdown
in liver function.
They
also reported that rates of spontaneous abortions, fetal malformations,
congenital defects, chromosome aberrations, reactions to infectious
disease,
and morbidity and mortality were not affected by TCDD exposure. As reported
by the American Medical Association's Council on Scientific
Affairs,
"The
most recent progress report on the long-term epidemiologic survey of the
residents of the Seveso area emphasizes the preliminary
nature of their

�. .

CRS- 5

IB80040

UPDATE-04/20/82

findings and reiterates the conclusions of prior investigators.
Except for
the skin, no organs or body functions were impaired.
No derangement of
gestation, no fetal lethality and loss, no gross malformations-, no growth
retardation at term and no cytogenetic abnormalities have yet occurred."
Health effects of domestic use of 2,4,5-T have been
kept
under
surveillance by various Government agencies for some years.
In April
1970,
the Departments of Agriculture, Interior, and Health, Education and Welfare
jointly announced the suspension of certain uses of 2,4,5-T following studies
indicating that it was a teratogen.
On Apr. 21, 1978,
the Environmental
Protection Agency (EPA) issued a Rebuttable Presumption Against
Registration
(RPAR) on 2,4,5-T, finding that the herbicide had exceeded certain
risk
criteria and inviting comments from interested parties. The RPAR was based
on toxicological data from animal
studies showing a correlation between
2,4,5-T exposure and cancer and birth defects. One of the comments received
was from Alsea, Oregon, claiming
that there was a high incidence of
miscarriage among area women following spraying of the local forests with
2,4,5-T. EPA investigated this claim and reported its conclusion that the
incidence of spontaneous abortion over a 6-year period in Alsea was higher
than the rates in two other regions of Oregon that had lower rates of 2,4,5-T
usage. Based on the combination of evidence from the animal studies and the
Alsea study, EPA announced the emergency suspension of the domestic use of
2,4,5-T on forests, pastures, and rights-of-way on Feb. 28, 1979.
The Alsea
study has been criticized on methodological grounds by various groups, and
its results are rejected by a number of writers.
EPA hearings
on
cancellation of 2,4,5-T began in June 1979.
On Mar. 24, 1981,
EPA and Dow
Chemical requested a recess in the hearing to discuss the possiblity of
negotiating a settlement.
The recess has been
extended
while
the
negotiations continue.
Herbicide Spraying in Vietnam
Approximately 107 million pounds of herbicides were aerially disseminated
on 6 million acres of South Vietnam (an area about the size of Connecticut)
from January 1962 to February 1971.
Approximately 276,000 gallons of Agents
Green, Pink, and Purple were sprayed in South Vietnam prior to 1965 when they
were replaced by Agent Orange. Approximately 11 million
gallo.ns of Agent
Orange were then sprayed in South Vietnam — making it the most widely used
herbicide of the war. Ninety percent of Agent Orange was sprayed on 2.9
million acres of inland forests and mangrove forests for defoliation, 8% was
sprayed on enemy crops for crop destruction, and the remaining 2% was sprayed
around base perimeters, cache sites, waterways, and communications lines.
The Air Force continued to operate its herbicide spraying program in South
Vietnam until the late 1960s when the National Cancer
Institute
released
results of an animal bioassay that showed 2,4,5-T to be teratogenic
and/or
fetotoxic in rodents, and newspapers in South Vietnam started reporting
health problems among the rural populations who had been exposed to such
herbicides. The Air Force first restricted the use of Agent Orange to areas
remote from populations
in October of 1969,
then stopped all airplane
spraying of Agent Orange in early 1970 and all helicopter spraying of Agent
Orange by 1971.
All remaining herbicide stocks were gathered and stored at
either Gulfport, Mississippi or Johnston Island in the Pacific until they
were incinerated at sea in 1977.
The following
table outlines
major military projects involving
handling of Agents Orange, Purple, Pink, or Green in South Vietnam.

the

�CRS-6

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UPDATE-04/2'0/82

MILITARY PROJECTS INVOLVING AGENTS ORANGE, PURPLE, PINK, OR GREEN
PROJECT

DATES

DESCRIPTION

AGILE

1960-68

Selection of herbicides., and development
and evaluation of defoliation techniques.

RANCH HAND

1962-71

Aerial spraying of herbicides in South
Vietnam.

Various USAF
Projects

1962-70

'Development and testing of aerial spray
equipment.

PACER IVY

1971

Air Force
Logistics
Command Project

1972-77

PACER HO

1977

Redrumming and movement of surplus
herbicide from South Vietnam to
Johnston Island.
Maintenance of herbicide inventory
and research on options for disposal.
Dedrumming of herbicide inventory and
at-sea incineration of Agent Orange.

Each of these projects involved some human exposure to the herbicide
2,4,5-T and its contaminant, TCDD. The difficulty lies in
determining who may have been exposed and at what level.

�CRS-7

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UPDATE-04/20/82

Personnel Exposed
The early trials that were conducted in South Vietnam to improve aircraft
spray systems (1960 to early 1962) were conducted by USAF personnel assigned
to the Special Aerial Spray Flight Division, Langley AFB, Va. (USAF personnel
engaged in the herbicide program did not receive permanent change of station
assignments to South Vietnam until 1964 -- thus making it more difficult to
track personnel who may have been exposed to herbicides). During late
1962
and early 1963, the Crops Division at Fort Detrick and the USAF Armament
Laboratory at Eglin Air Force Base, Florida were involved in efforts to
provide improvements in spray system components in support of Operation RANCH
HAND.
Most of the personnel involved in the actual handling of herbicide drums
were Vietnamese.
However, a USAF flight mechanic or crew chief was
responsible for ensuring that the aircraft were properly loaded and that the
spray systems were functional. Each herbicide aircrew consisted of a pilot
and a copilot (both usually
officers) and a flight mechanic/spray unit
operator (usually enlisted). The aircrews were frequently joined by South
Vietnamese and U.S. observers. As noted in a USAF report, "within the
aircraft, it was not uncommon to have herbicide leakage from around the
numerous hose connections joining the spray tank and pumps with the wing and
aft spray booms. In hot weather, the odor of herbicide within the aircraft
was decidedly noticeable."
The USAF has data on 6,542 herbicide spraying missions that took place
between August 1965 and February 1971 on its "HERBS" computer tape.
These
data were compiled on a mission-by-mission basis from reports and files in
various commands and offices in South Vietnam and the United States.
The
HERBS tape contains the following data for each mission:
date; mission
number; location; province and UTM coordinates; type of herbicide (basically,
Agents Orange, White, or Blue); quantity of herbicide; area covered; purpose
of mission (defoliation, crop destruction, etc.); and type of aircraft (plane
or helicopter). The NAS used the HERBS tape in its evaluation of the effects
of herbicides on South Vietnam. After evaluating the HERBS data, the NAS
concluded that the HERBS tape accounted for approximately 86% of all
herbicide operations in South Vietnam and that "despite certain
recognized
deficiencies," the HERBS tape is "a reliable source for an assessment of the
major part of the herbicide operation in South Vietnam" and "is the best and
in fact the only available comprehensive computation of the major part of the
herbicide operations conducted in the Vietnam war."
When the DOD suspended all use of 2,4,5-T in South Vietnam, the USAF was
left with an inventory of 2.22 million gallons of unused Agent Orange
(1.37
million gallons which had been shipped to South Vietnam and 0.85
million
gallons which were waiting to be shipped at the Naval Construction Battalion
Center at Gulfport, Mississippi). In April 1972, the 1.37 million gallons of
Agent Orange were moved from South Vietnam to Johnston Island in the Pacific
Ocean for storage. The total amount of TCDD in the remaining Agent Orange
stock was approximately 44.1
pounds.
Problems began to arise in both
locations as drums reportedly began to leak and the USAF expressed concern
over further leakage problems that could occur if a tornado hit the
Mississippi site or if a typhoon hit the Pacific site.
After exploring a
number of options, the USAF decided to dispose of the Agent Orange by burning
it at high temperatures at sea on the Dutch incinerator
ship named the
"Vulcanus." The Agent Orange was drained from the drums at each site and

�CRS- 8

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UPDATE-04/20/82

transferred to the Vulcanus. The empty drums were then rinsed with diesel
fuel and crushed. The rinse fluid was combined with the Agent Orange for
incineration at sea. A total of 15,480 drums of Agent Orange were processed
at the Mississippi site between May 24, 1977, and June 10, 1977, by
approximately 110 USAF officers/technicians from the five Air Logistics
Centers of the Air Force Logistics Command (located at Kelly AFB Texas;
Hill
AFB, Utah; Warner Robbins AFB, Georgia; Tinker AFB, Oklahoma; and McCellan
AFB, California). A total of 24,795 drums of Agent Orange were processed at
the Johnston Island site between July 27, 1977,
and Aug. 23,
1977.
Approximately 100 civilian employees hired by a contractor
performed the
dedrumming process. At both the Johnston Island and Mississippi
sites,
workers were provided with daily changes of work clothes and some with
protective clothing. The Agent Orange was incinerated at sea in the period
from July to September 1977.
Results of industrial hygiene studies conducted
at the time of the disposal operation by the U.S. Air Force
(Gulfport)
and
the Battelle Memorial Institute
(Johnston
Island) revealed no immediate
adverse health effects among the personnel involved in the operation.
Department of Defense, Efforts
The USAF has stated that it can now identify 1,264
servicemen who were
directly exposed to Agent Orange as they handled herbicide., containers and
flew spraying missions in South Vietnam.
The Air Force has initiated a
health effects study of Air Force personnel involved in operation
"Ranch
Hand," who sprayed Agent Orange in Vietnam. The Department of Defense
(DOD)
believes that these individuals had at least 1000
ti-mes more exposure .to
Agent Orange than the average ground troops. The epidemiological study will
try to determine whether a causal relationship
can be established
between
exposure to the 2,4-D/2,4,5-T mixture and long-term health effects. Although
the study was originally scheduled to begin in October 1979, peer review of
its protocols forced delays.
The University of Texas School
of Public
Health, the U.S. Air Force Scientific Advisory Board and the Armed Forces
Epidemiological Board reviewed the
study
protocols
and
recommended
modifications. Then the Air Force asked the National
Academy of Sciences
(NAS) to review the protocols.
On May 6, 1980,
the NAS
announced
recommendations that the scope and duration of the study be expanded to
increase the likelihood of obtaining definitive data.
NAS also expressed
concern about the public perception of credibility
and impartiality
of a
study conducted internally by the Air Force. The Interagency Work Group's
Scientific Panel, however, has recommended that the study, as designed by the
Air Force, be conducted because, despite its limitations,
it provides "a
focus as to the type of health effects that may possibly
occur in other
(ground troop) personnel."
The Ranch Hand study is proceeding in several phases and will continue for
20 years.
The first phase consists
of a detailed
medical
history
questionnaire, which has been administered to the Ranch Handers in their
homes by trained interviewers from Louis Harris and Associates.
A carefully
matched control group, selected from military records held by the Air Force,
has also been interviewed.
The first data from the questionnaire
should be
available by mid-summer 1982.
Also underway is the second phase of the
study, a 3-day series of physical examinations, including a battery of
psychological tests, which will be given to both the study group and the
controls. The contractor for this phase is Kelsey-Seabold of Houston.
The
exams are scheduled to be completed by September 1982,
with
preliminary
findings available 2 to 3 months later. Follow-up exams will be conducted at
1, 3, 5, 10, and 20 years. A mortality analysis on the Ranch Hand group is

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in progress at the Air Force School of Aerospace Medicine, with data
anticipated around August 1982, and a mortality tracking program will be
continued throughout the study. Information on the health status of the
veterans, as shown by the questionnaires and the physical examinations, will
provide data for a morbidity analysis.
Many of the veterans who have filed claims with the VA for compensation
for health effects caused by exposure to TCDD in South Vietnam did not hold
jobs that caused direct exposure to 2,4,5-T. They claim that their exposure
occurred indirectly either by being sprayed with overhead planes
(although
substances other than herbicides were also sprayed from planes) or by being
exposed to 2,4,5-T in the environment.
According to the DOD, military
personnel did not usually enter areas sprayed with Agent Orange until 4 to 6
weeks after treatment.
However, a recent General
Accounting
Office
investigation concluded that a large number of Marines in the I Corps section
of Vietnam from 1966-1969 were in, or close to, areas sprayed with Agent
Orange on both the day of spraying and within 4 weeks afterward.
Some Army
units were also close to Agent Orange spraying.
The Department of Defense has recently made progress in identifying ground
troops that may have been exposed to Agent Orange. Two Army and one Marine
battalion - 31st Engineer Battalion, 2050 troops; 1st Squadron, 9th Calvary
(Air Mobil), 2300 troops and 3rd Battalion, 1st Marines, have been identified
as being in areas of Agent Orange operations.
Exact numbers, locations, and
identities of individuals who may have been sprayed are impossible to
determine.
Veterans' Problems and Veterans^ .Administration E_f_fO'rts
The first reports of veterans' concerns over health effects of exposure to
2,4,5-T began to appear in late 1977 and early 1978, following media coverage
of several veterans' claims.
Veterans have associated a number of illnesses
with exposure to 2,4,5-T, including skin conditions, fatague, nervousness,
numbness in extremities, vision and/or hearing impairments, birth d'efects in
offspring, reduced libido, miscarriages, impotency, respiratory problems,
gastro-intestinal tract disturbances, and various cancers, as well as a
variety of other illnesses.
As of Apr. 1, 1982, the VA had received 13064 claims for damage reportedly
related to in-service exposure to herbicides? 2986 claims have been made due
only to exposure to the herbicides and not for any specific condition; 10078
claims have been filed for specific conditions related to herbicide exposure,
but 3469 of these have not had the diagnosis con-firmed by medical
authority.
Of the 6609 claims with a confirmed diagnosis, 923 (13.7%) have been allowed
for reasons other than Agent Orange exposures and 5686
(86.3%) have been
denied. Approximately 93% or 858 of the total 923 claims allowed were for
service-connected skin conditions, and the remaining 7% or 65 claims were
allowed for cancer, psychiatric and neurological
conditions, and various
other miscellaneous disabilities. The 5686 claims denied fall into the
following categories (many claims have more than one claimed diagnosis): 3055
for various skin conditions; 2335 for nervousness, headache, or fatigue; 886
for paralysis
or numbness; 751 for gastro-intestinal
or genito-urinary
conditions; 399 for various malignancies; 356 for impaired sexual activity;
394 for eye, ear, nose, and throat conditions; 274 for lung conditions; 227
for cardiovascular conditions; and 137 for miscellaneous conditions. The VA
has not awarded compensation for the claims of chronic illnesses
related to
Agent Orange exposure because of the lack of valid human data to prove a

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cause and effect relationship between exposure to a 2,4,5-T/2,4-D mixture
and/or TCDD and specific chronic health effects. Previously, the difficulty
of determining which veterans' were or were not exposed to Agent Orange was
also a factor in denying compensation, but more recently the VA has conceded
exposure for all veterans who were in Vietnam.
The VA is maintaining a registry of all Vietnam veterans who have come to
VA hospitals and health care facilities expressing concern about possible
herbicide-related health problems. Each such veteran, whether experiencing
any health problems or not, is given a physical examination; currently, some
2700-2800 exams are being conducted each month. Data from all the exams is
being computerized into a central Agent Orange Registry in addition to the
individual records being maintained at the local VA facilities.
As of Mar.
25, 1982, 81,670 veterans had received the initial exam, and about 61,000 of
the records had been coded into the computer. Information from the registry
is being analyzed to determine if the veterans have an increased rate of any
particular diseases.
Thus far, nothing unusual or unexpected has turned up.
Treatment of any health problems uncovered by the exams is handled under
normal VA procedures regarding service-connection, ability to pay for medical
care, etc., with the exception that special guidelines have been issued for
the handling of conditions possibly related to Agent orange.
In the Federal
Register of Dec. 2, 1981,
pursuant to Public Law 97-72, the VA issued
guidelines for use by its physicians to "assist them in making determinations
in individual cases as to whether a disability
may have been caused" by
exposure to Agent Orange. Even though treatment may be given for some
conditions, the VA specified that "In accordance with congressional intent, a
determination to furnish care under this authority does not establish that
the condition for which medical care is provided is service-connected" for
purposes of compensation or vocational rehabilitation eligibility.
Three additional VA activities on Agent Orange include participation
in
the tissue registry, the Chloracne Task Force, and investigations into TCDD
residues in body fat tissue of veterans. When VA facilities perform surgery
or autopsies on Vietnam veterans, tissue samples are taken and sent to the
Armed Forces Institute of Pathology where a special tissue registry is being
maintained. Examination of approximately 800 specimens has so far shown no
significant clustering of tumors or other particular
disease features. The
Chloracne Task Force was established in response to a congressional request
to sift out those cases of skin conditions that either resemble or are truly
Chloracne. Those veterans whose medical records show a definite possibility
of Chloracne will be invited to come to non-VA clinics for re-examination
by
dermatologists who have an expert knowledge of the disease.
The VA has
conducted a study to determine if TCDD can be detected in the body fat
tissues of Vietnam veterans at any higher levels than in veterans who were
not in Vietnam. Dioxin in body fat is measured in parts per trillion, levels
which are at the technological limits of available
detection methods.
The
test requires surgical removal of tissue from the abdomen and chemical
analysis of the sample on
gas
chromatography/high
resolution
mass
spectrometry instruments. The results of the study were inconclusive, and
the VA has decided that the reliability of the procedure is not sufficient to
warran-t its use in attempting to verify dioxin exposure.
An additional
problem is that dioxin contamination
is so ubiquitous (from domestic
herbicide use and from its formation in municipal incinerators) that it may
likely be found in everyone's fat tissue.
As mandated in P.L. 96-151, the Veterans' Affairs Amendments, the VA is
currently preparing to perform an epidemiological study of Vietnam veterans
exposed to Agent Orange. Although the study's protocol has been developed

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UPDATE-04/20/82

and validated by an independent group, the VA will perform the testing and
collect the data, with oversight by a non-VA
scientific
committee.
Procurement of an independent contractor for the study's protocol was delayed
for 14 months by a protest filed by the National Veterans Law Center
(NVLC) .
The NVLC alleged that not only was the .VA violating procurement law, but also
the study as currently contemplated did not comply with the requirements of
P.L. 96-151. On Feb. 2, 1981, the General Accounting Office concluded its
investigation and denied the NVLC protest. On May 5, 1981, the VA announced
the awarding of a contract to the University of California at Los Angeles
(UCLA) School of Public Health for the design of the epidemiological study.
UCLA submitted its first draft of the protocol to the VA in August 1981;
it
was peer-reviewed by the VA Advisory Committee on Health-Related
Effects of
Herbicides, by the Office of Technology Assessment, and by the Science
Panel
of the Agent Orange Working Group. All the review groups judged the draft
protocol to be inadequate and not in compliance with the contract. UCLA has
since modified the protocol, expanding on problem areas and incorporating the
suggestions of the review groups; its final submission to the VA is due April
29, 1982.
As with the Ranch Hand study, this epidemiological study will have
two main parts:
a questionnaire on health status and
medical
and
occupational history, and a physical exam with laboratory workup. The study
group will be 18,000 veterans, divided into 3 cohorts of 6000 each.
Two of
the cohorts will have had Vietnam service, and will be distinguished as
having a high or a low likelihood of herbicide exposure.
The third cohort
will be veterans with non-Vietnam military service.
Inclusion of the third
group will generate data about the health effects of Vietnam service in
addition to the information expected about herbicide-related health
effects.
The study will commence with a pilot project to field test its procedures.and
the questionnaire.
P.L. 96-151 also mandated the VA to conduct a comprehensive review and
scientific analysis of the worldwide literature on Agent Orange and other
phenoxy herbicides. JRB Associates prepared the review under contract, and
the VA published the 2-volume study in October 1981.
The VA is now preparing
to contract for an update to the literature review, to reflect new reports
and data -that have appeared.
The Interagency Work Group on Phenoxy Herbicides and Contaminants,
established in December 1979,
recommended that the Centers for Disease
Control (CDC) perform a case-control study to see if there is an increased
incidence of specific malformations in children of Vietnam veterans.
The
population to be studied is a group of 7500 children who have birth defects
and who are registered in CDC's Birth Defects Program (in operation since the
late 1960s). Information on the families of these children, gained by
extensive interviews and questionnaires, will be compared with that for 300
normal controls. The data will be analyzed to see what risk factors in the
parents' lives, including military service in Vietnam, may be related to
increased incidence of malformations in their children.
CDC has completed a
pilot study on a representative sample of the two groups to test the
questionnaire and the procedures for finding the families.
The main study
will be started in late April 1982, and a preliminary report on the issue of
Vietnam service is expected in the fall of 1983.
Detailed analysis of the
data on all risk factors will take several years to complete.
On Sept. 22, 1980, the Work Group held its first public meeting to discuss
problems and proposals related to exposure to herbicides. On Jan. 19,
1981,
the Secretary of Health and Human Services established the "Advisory
Committee on Special Studies Relating to the Possible Long-Term Health
Effects of Phenoxy Herbicides and Contaminants" to advise the Secretary and

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UPDATE-0'4/20/82

the Chair of the Interagency Work Group on Herbicides concerning the Advisory
Committee's oversight of the conduct of the Ranch Hand Study being conducted
by the Air Force. In its seventh report to the White House, the Work Group's
Scientific Panel concluded that:
While it is difficult to accept logically that a
single causative factor -- Herbicide Orange -- could be
responsible for such a diverse set of health effects as
alleged by Vietnam veteran claims to the VA , there is no
definitive evidence that permits selective exclusion of
some of these illnesses. Further, it is possible that
some of these health effects are occurring as a consequence
of Vietnam^ service but not due to exposure to Herbicide
Orange. The Science Panel is not aware of any data that
suggest a modification of its previous recommendation that
the •focus of a study of Vietnam veterans should be
broadened to consider Vietnam service as the exposure
factor rather than focus solely on Herbicide Orange
exposure.... The Science Panel is in receipt of data
which indicate that there is at best a remote chance of
accurate identification of specific ground troops who were
exposed to Herbicide Orange.... The Panel is therefore of
the opinion that design of a scientifically valid Herbicide
Orange study of ground troops may not be possible. If
the focus of a study of Vietnam veterans is broadened to
consider Vietnam service as the exposure factor, a study
of ground troops is necessary and a scientifically valid
study can be designed.
On July 17, 1981,
the Interagency Work Group was renamed and its
membership expanded. Now called the Agent Orange Working Group, it is part
of the Cabinet Council on Human Resources.
The Department of Health and
Human Services is the lead agency.
Because the VA currently recognizes only chloracne as a human health
effect that can be proven to be caused by exposure to 2,4,5-T, veterans may
have difficulty being compensated for even those effects for which there is
strong animal evidence (i.e., cancer and birth defects caused in utero which
are those birth defects that cannot be caused by the father and require the
mother and fetus to be exposed during the actual pregnancy).
Veterans who
claim compensation for health effects which are not supported by strong
animal data (i.e., mutations -- which could cause genetic defects in the
father's sperm that would affect children conceived after exposure) may have
an even tougher case to argue.
The veteran's question then becomes: How much evidence is required to
prove the right to compensation?
On whom does the burden of proof lie
(the
veteran or the VA)? .If more evidence is needed, who will generate it? And
finally, what constitutes fair treatment of veterans while the necessary data
are being gathered?
Congressional Action of the 96th Congress
The 96th Congress responded to the problems of establishing
a cause and
effect relationship between veterans' exposure to herbicides in South Vietnam
and the various health problems they are now experiencing by holding hearings
and enacting legislation.

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The Subcommittee on Oversight and Investigations, of the House Committee on
Interstate and Foreign Commerce held hearings on June 24 and 25, 1979,
to
hear testimony from veterans who allegedly have been affected by herbicide
exposure and from the Veterans Administration regarding its efforts to
unequivocally determine the relationship between herbicide exposure and
health effects. The Subcommittee on Medical Benefits and Facilities of the
House Committee on Veterans' Affairs held two sets of hearings on the hazards
associated with TCDD, veterans' complaints of health effects associated
with
Agent Orange exposure, and Veterans Administration's efforts to resolve the
Agent Orange problem.
The Senate Veterans' Affairs Committee also held hearings to
Agent Orange problem.

examine

the

As a step to gain access to records to locate veterans who may have been
exposed to herbicides in-service,
Title V of H.R.
2282, the Veterans'
Disability Compensation and Survivors' Benefits Amendments of 1979,
requires
the Director of the National Institute for Occupational
Safety and Health,
upon request by the VA (or other appropriate agency) to request the current
mailing address from the Internal Revenue Service of persons whom the VA
certifies may have been exposed to occupational
hazards.
H.R.
2282 was
passed in lieu of its companion bill, S. 689, and became Public Law 96-128 on
Nov. 28, 1979.
Title III of H.R. 3892, the Veterans' Affairs amendments, directs the
Veterans Administration to conduct an epidemiological study of the long-term
health effects on individuals from exposure to dioxins in Vietnam, upon the
Office of Technology Assessment's
(OTA) approval of its protocol.
Its
companion bill, S. 1039, was incorporated in H.R. 3892 as an amendment, and
the measure was enacted by Congress and signed by the President on Dec. 20,
1979 (P.L. 96-151) .
If enacted, S. 2096 would have directed the Secretary
of Health,
Education, and Welfare (now, Health and Human Services)
to undertake an
epidemiological study to determine the long-term adverse human health effects
associated with exposure to dioxins produced during the manufacture of
phenoxy herbicides. This bill proposed to investigate the long-term health
effects of exposure to dioxins, in general, not just to Agent Orange.
As
similarly incorporated in H.R. 3892, S. 2096 would have required that the
study's protocol be approved by the Congressional Office of Technology
Assessment. This bill was presented to the President on Dec. 21, 1979,
and
vetoed by him on Jan. 2, 1980.
President Carter vetoed the bill because the
White House counsel believed that such a procedure violated the separation of
power between the legislative branch and the executive branch.
He did not
feel that the Department of Health and Human Services' study protocol
should
be subject to approval by a congressional agency.
Title X of H.R. 5288, the Veterans' Rehabilitation Program and Veterans'
Educational Assistance Program would have directed the Secretary
of Health
and Human Services to conduct a study of veterans and other groups exposed to
the herbicide known as "Agent Orange" to determine if there may be adverse
health effects associated with such exposure. Like H.R. 3892 (P.L.
96-151)
and S. 2096, the bill called for OTA approval of the study's protocol.
The
bill also would have required the Secretary of Health and Human Services to
coordinate its efforts with other studies in the Federal Government.
During
the debate on S. 1188,
its companion bill, the
Disabled
Veterans'
Rehabilitation Act, the Senate adopted an amendment offered by Senator

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UPDATE-04/20/82

Cranston to expand the study on health effects of exposure to Agent Orange to
include other factors related to service in Vietnam. The Senate also adopted
an amendment offered by Senator
Heinz requiring the VA to promulgate
regulations regarding guidelines to resolve veterans' disability claims based
on exposure to Agent Orange.
The ' amendments were striken by the House
because they were considered to be "non-germane" to the primary focus of the
bill.
S. 1872 (the Vietnam Veterans' Act); H.R.
6050 (the Vietnam Veterans'
Act); H.R. 6377 (the Vietnam Era Veterans Agent Orange Act); each would have
established a presumption of service-connected disability for health
effects
in Vietnam veterans (and birth defects in their children) exposed to Agent
Orange. H.R. 8238 (Independent Agent Orange Study) would have directed the
Veterans Administrator to request the National Academy of Sciences to conduct
a study on veterans exposed to Agent Orange.
H.R. 8300 would have expanded
the scope of the Agent Orange study currently being coordinated by the VA and
would have established deadlines for promulgating regulations related to
Agent Orange exposure claims. These bills received no action.
LEGISLATION
P.L. 97-72, H.R. 3499
Veterans' Health Care, Training and Small Business Loan Act of
1981.
Amends title 38, U.S. Code, to extend the Vietnam-era veterans'
readjustment
counseling program, to provide medical care for Vietnam veterans exposed to
herbicide defoliants (including Agent Orange), to recover the cost of certain
health care provided by the VA, and authorizes the VA to expand the scope of
its epidemiological study on the health effects of Agent Orange, and other
purposes. Introduced May 7, 1981;
referred to Committee on Veterans'
Affairs. Committee consideration and mark-up session held May 12.
Reported
to House (amended) by Committee on Veterans' Affairs (H.Rept. 97-79) May 19.
Passed House (amended) June 2, 1981.
Received in the Senate June 3.
Senate
struck all after the Enacting Clause and substituted the language of S. 921,
June 16. Passed Senate in lieu of S. 921 with amendments, June 16,
1981.
House concurred in Senate amendments with amendments Oct.
2, 1981.
Senate
agreed to House amendments Oct. 16, 1981.
Signed into law Nov. 3, 1981.
H.R.

523

(Roe)

Amends Title 38, U.S. Code, to waive the 1-year limitation on claims for
compensation from the Veterans Administration for disabilities
and diseases
incurred in or aggravated by military service in the case of claims by
veterans who served in Southeast Asia during the Vietnam era for compensation
for disabilities resulting from exposure to the phenoxy herbicides known as
Agent Orange or other phenoxy herbicides.
Introduced Jan. 5, 1981;
referred
to Committee on Veterans' Affairs.
H.R. 1173

(Montgomery, by request)

Amends section 307 of P.L. 96-151, by assigning
the responsibility
of
designating a protocol for, and conducting an epidemiological
study of,
veterans who were exposed to Agent Orange, to an independent
scientific
agency. Introduced Jan. 22, 1981;
referred to Committee on Veterans'
Affairs.
H.R. 1962

(Oilman)

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Amends the Veterans Health Programs Extension and Improvement Act of
1979
to require the Veterans Administration and the National Academy of Sciences
to enter into an agreement under which the Academy will
conduct an
epidemiological study of veterans exposed to Agent Orange.
Introduced Feb.
19, 1981; referred to Committee on Veterans' Affairs.
H.R. 2157

(Mottl)

Expands the scope of a study required to be conducted by the Administrator
of Veterans' Affairs concerning the effect on humans of exposure to the
chemical known as Agent Orange.
Introduced Feb. 25, 1981:
referred to
Committee on Veterans' Affairs.
VA requested Executive comment Mar. 2, 1981.
Referred to Subcommittee on Hospitals and Health Care Apr. 28. Hearings held
Apr. 30. Subcommittee consideration and mark-up session held.
Clean
bill
forwarded to full committee.
H.R. 2297

(Downey)

Amends Title 38, United States Code, to waive the 1-year limitation
on
claims for compensation from the Veterans Administration for disabilities and
disease incurred in or aggravated by military service in the case of claims
by veterans who served in Southeast Asia
during the Vietnam era for
compensation for disabilities
resulting from exposure to the
phenoxy
herbicides known as "Agent Orange" or other phenoxy herbicides.
Introduced
Mar. 4, 1981; referred to Committee on Veterans' Affairs.
H.R. 2493

(Daschle)

Amends Title 38, United States Code, to provide a presumption of service
connection for the occurrence of certain
diseases in veterans who were
exposed to herbicides in Southeast Asia during the Vietnam era.
Introduced
Mar. 12, 1981; referred to Committee on Veterans' Affairs.
H.R. 2953 (Daschle)
Entitles veterans exposed to Agent Orange
during the Vietnam era to
specified medical benefits.
Extends the period during which veterans of such
era may initially request psychological
readjustment counseling.
Extends
specified educational assistance without delimiting periods for vocational
training for specified veterans determined to be in need of such
assistance.
Introduced Apr. 1, 1981;
referred to Committee on Veterans' Affairs.
Referred to Subcommittee on Hospitals and Health Care Apr. 28. Hearings held
Apr. 28. Subcommittee consideration and mark-up session held Apr. 30, 1981.
H.R. 3163

(Railsback)

Requires the Secretary of Health and Human Services to arrange for an
independent epidemiological
study of persons
exposed to Agent Orange.
Introduced Apr. 8, 1981;
referred to Committee on Energy and Commerce.
Referred to Subcommittee on Health and the Environment Apr. 9, 1981.
S. 636 (Cranston et al.)
Entitles the United States to recover the costs of certain
medical
care
and services furnished to a veteran for a non-service-connected
disability
when disability is covered by another form of insurance
or compensation.
Permits the expansion of the scope of the epidemiological
and literature

�CRS- 16

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UPDATE-04/20/82

study of the long term adverse health effects of exposure to Agent Orange
during the Vietnamese conflict to include the effects of other factors.
Introduced Mar. 5, 1981; referred to Committee on Veterans' Affairs.
S. 689 (Heinz)

Amends section 307 of the Veterans Health Programs Extension
and
Improvement Act of 1979 to require the promulgation of regulations containing
guidelines for resolving claims for veterans benefits based on exposure, to
Agent Orange, and for other purposes. Introduced Mar. 12, 1981; referred to
Committee on Veterans' Affairs.
Hearings held Apr. 30, 1981.
S. 921

(Simpson)

Extends the authority of the Administrator
of Veterans' Affairs to
contract for hospital care or medical services in Puerto Rico and the Virgin
Islands without reference to patient loads or incidence of provision of
medical services for veterans treated by the Veterans' Administration in the
contiguous 48 States. Introduced "Apr. 8, 1981;
referred to Committee on
Veterans' Affairs.
Reported with amendment May 15, 1981
(S.Rept.
97-89);
H.R. 3499 passed in lieu (see P.L. 97-72 above) June 16, 1981.
S. 1345 &lt;Heinz)
Authorizes the Administrator of the Veterans' Administration to provide
hospital or nursing home care to a veteran for treatment of a condition
associated with exposure to Agent Orange during service in Vietnam.
Extends
the Vietnam-era veterans' readjustment counseling program.
Directs the
Administrator to expand the scope of the epidemiological study of long term
adverse health effects of other factors involved in such service. Introduced
June 8, 1981; referred to Committee on Veterans' Affairs.
S. 1953

(Specter)

Amends title 38, United States Code to provide a presumption of service
connection for the occurrence of certain diseases
in veterans who were
exposed to phenoxy herbicides while serving in Southeast Asia during the
Vietnam era.
Introduced Dec. 15, 1981; referred to Committee on Veterans
Affairs.
HEARINGS
U.S.

Congress.
House. Committee on Interstate and Foreign
Commerce. Subcommittee on Oversight and Investigations.
Agent Orange: exposure of Vietnam veterans.
Hearing, 96th Congress,
2d session. Sept. 25, 1980.
249 p.
Involuntary exposure to Agent Orange and other toxic
spraying. Hearings, 96th Congress,
1st session. June 26 and 27, 1979.
256 p.

U.S.

Congress. House. Committee on Veterans' Affairs. Ad Hoc
Subcommittee.
Status of Vietnam veterans in the Bay area.
Hearing, 96th Congress, 2d session. Apr. 10, 1980.
64 p.

U.S.

Congress.
House. Committee on Veterans' Affairs.
Subcommittee on Hospitals and Health Care.

�%

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Legislation to improve medical programs administered by
the Veterans Administration (H.R. 2157, H.R. 2953, and H.R. 2999).
Hearings, 97th Congress, 1st session. Apr. 28, 1981.
54 p.
U.S.

Congress. House. Committee on Veterans' Affairs.
.Subcommittee on Medical Facilities and Benefits. Herbicide
"Agent Orange". Hearing, 95th Congress, 2d session. Oct. 11,
1978.
62 p.
Oversight hearing to receive testimony on Agent Orange.
Hearing, 96th Congress, 2d session. Feb. 25, 1980.
121 p.

----- Oversight hearing to receive testimony on Agent Orange.
Hearing, 96th Congress, 2d session. July 22, 1980.
459 p.
--—•- Scientific community report on Agent Orange. Hearing, 96th
Congress, 2d session. Sept. 16, 1980.
145 p.
U.S.

Congress. House. Committee on Veterans' Affairs.
Subcommittee on Oversight and Investigations. Current
status of Agent Orange studies. Hearing, 97th
Congress, 1st session. May 6, 1981.
385 p.

U.S.

Congress.
Senate.
Committee on Veterans' Affairs. Agent
Orange update and appendix: Agent Orange activities (part II).
Hearing, 96th Congress, 2d session. Sept. 10, 1980.
1368 p.
Oversight on issues related to Agent Orange and other
herbicides. Hearing, 97th Congress, 1st session. Nov. 18,
1981.
(not yet printed)
• VA health resources and program extensions and appendix:
Agent Orange activities.
Hearing, 96th Congress, 1st session,
on S. 741 and S. 196.
Apr. 10,. 1979.
462 p.
• Veterans' Programs Extension and Improvement Act of 1981.
Hearing, 97th Congress, 1st session, on S. 26 (titles
II and III, only), S. 380, S. 458, S. 636, S. 689, S. 872, S. 914,
S. 921, and related bills. Apr. 30, 1981.
685 p.
• Vietnam veterans' readjustment. Hearings, 96th Congress, 2d
session.
Feb. 21, Mar. 4, and May 21, 1980.
Part 2.
595-2082 p.

ADDITIONAL REFERENCE SOURCES
American Medical Association.
Council on Scientific
Affairs.
Health effects of "Agent Orange" and
dioxin contaminants (Executive Summary).
1981.
6 p.
Behrens, Richard, et al. Comments from CAST (Council on
Agricultural Science and Technology): Dioxin.
1978,
9 p.
Bucfc, Craig. The Death of a nation.
Aug. 28, 1978:
49-50, 52-55.

New west, v. 3,

�CRS-18

IB80040

UPDATE-04/20/82

Cookson, Clive. "Emergency" ban on 2,4,5-T herbicide
in U.S. Nature, v. 278, Mar. 8, 1979:
10'8-110.
Davis, Donald E. et al. Comments from CAST (Council
on Agricultural Science and Technology): Agent
orange. 1978.
5 p.
Galston, Arthur W. Herbicides: a mixed blessing.
v. 29, February 1979:
85-90.

Bioscience,

International Agency for Research on Cancer.
IARC monographs on
the evaluation of the carcinogenic risk of chemicals to
man: 2,5,5-T, vol. 15, August 1977.
JRB Associates.
Review of literature on herbicides,
including phenoxy herbicides and associated
dioxins. Washington, Veterans Administration,
1981.
2v.
Laporte, Joan-Ramon. Multinationals and health: reflections on
the Seveso catastrophe.
International journal of health
services, v. 8, no. 4, 1978:
619-632.
National Research Council. The effects of herbicides in South
Vietnam: Part A. Summary and conclusions. Washington,
National Academy of Sciences, 1974.
AD-774-749.
398 p.
Peterson, Jeannie. Seveso:
1978:
232-239.

the event.

Ambio, v. 7, no. 5-6,

Reggiani, G. Localized contamination with TCDD - Seveso, Missouri, and
other areas. In: Halogenated biphenyls, terphenyls,
naphthalenes, dibenzodioxins and related products, ed. Renate
D. Kimbrough. Amsterdam, New York, Oxford, Elsevier/North-Holland
Biomedical Press, 1980.
Severe, Richard. Seveso: lessons from an escape.
June 17, 1978:
101-102, 104-106, 108.
U.S.

Economist, v. 2.67,

General Accounting Office. Health effects of exposure to
herbicide orange in South Vietnam should be resolved,
Apr. 6, 1979.
CED-79-22.
U.S. ground troops in South Vietnam were in areas sprayed
with herbicide orange. Nov. 16, 1979.
FPCD-80-23.

Young, Alvin et al. The toxicology, environmental fate and human
risk of herbicide orange and its associated dioxin. The
Surgeon General, U.S. Air Force, Washington, D.C.
October 1978.
Walsh, John. Seveso: the questions persist where dioxin created a
wasteland. Science, v. 197, Sept. 9, 1977:
1064-1067.
Whiteside, Thomas.

Defoliation.

New York, Ballantine,

•- The pendulum and the toxic cloud.

New Haven, Yale

1970.

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CRS-19

IB80040

University Press, 1979.
Zimmerman, David R. Agent Orange: Vietnam's lingering
poison. American health, v. 1, no. 1, Mar./Apr.
1982: 68-72.

UPDATE-04/20/82

�Signs, Symptoms, and Disorders Reported After Occupational Exposure to TCP, 2,4,5-T or TCDD
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Zelikov and Danilov (88)
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Number entries in table reflect the number of cases in which sign, symptom or disorder was
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c
Numbers do not include cases represented by "+" and totals may represent some double counting
due to the overlap to studies by Jirasek et al. and Pazderova et al.
SOURCE:

Young, Alvin et al. The Toxicology, Environmental Fate, and Human Risk of Herbicide
Orange and Its Associated Dioxin, p. VI-14. (Numbers in parentheses identify sources
in Young's bibliography.)

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