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ABATEMENT OF INFLAMMATION AS A MEANS TO COMBAT HEAT STRESS IN FINISHING LIVESTOCK

Investigators
Yates, D.
Institutions
University of Alaska
Start date
2020
End date
2023
Objective
The difficulty and expense of mitigating environmental heat stress makes it unrealistic for most feedlots. Therefore, producers would most benefit from nutritional and/or pharmaceutical strategies to manage the impact of heat stress on their animals. Our goal is to identify the most effective physiological targets for treatments that obtain the best possible outcomes for wellbeing and performance. To this end, the overall objective of the project is to determine the extent to which reducing inflammation associated with heat stress improves skeletal muscle growth and metabolic efficiency. Inflammatory factors are powerful regulators of muscle growth and metabolism, and their activity can be controlled by pharmaceutical and nutritional molecules. Greater inflammation is a mediator of heat stress, and understanding its role may lead to effective strategies for protecting heat-stressed livestock. We developed 2 specific objectives to this end. Objective 1. Mitigating the impact of heat stress on muscle growth & body composition by reducing inflammation. Objective 2. Mitigating the impact of heat stress on metabolic efficiency and wellbeing by reducing inflammation.
Funding Source
Nat'l. Inst. of Food and Agriculture
Project source
View this project
Project number
NEB-26-246
Accession number
1021843