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Adaptation and Divergence among Aflatoxin-Producing Fungi and Optimized Use of Atoxigenic Strains

Investigators
Mellon, Jay; Cotty, Peter
Institutions
USDA - Agricultural Research Service
Start date
2001
End date
2006
Objective
  • Construct and develop criteria for selection and delivery of optimal Aspergillus flavus strains for competitive exclusion strategies that modify A. flavus populations in the field.
  • Determine behavior of A. flavus in soil and identify factors that dictate strain success.
  • Delineate adaptation and divergence among aflatoxin producing fungi with the goal of improved criteria for selection and monitoring of elite atoxigenic strains.
More information
  • Assess competitive differences amont atoxigenic strains under field conditions and the effects of long term applications of atoxigenic strains on the A. flavus community structure.
  • Identify factors that exert selective forces on A> flavus population structure and strain character.
  • Define distribution of atoxigenic vegetative compatibility groups and assess their adaptation to different cotton producing areas.
  • Define the evolutionary relationship of atoxigenic strains to both toxigenic strains and to strains of Aspergillus oryzae in order to help determine how aflatoxin producing ability may be selected against.
  • Establiish mechanisms of atoxigenicity and variability among phenotypes in rsponse to environmental modulators of aflatoxin production.
  • Apply genetic methods to quantify phylogenetic relationships among strains of A. flavus and to gain insights on ancestral versus adaptive traits.
  • Combine genetic and physiologic approaches to identify adaptive traits and delineate the extent to which geographical and ecological divergence has arisen within aflatoxin producing taxa.
Funding Source
Agricultural Research Service
Project number
6435-42000-018-00D
Accession number
404445
Categories
Mycotoxins