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(AH) Identification of immunodominant mimotopes of Campylobacter hepaticus from a phage display peptide library

Investigators
Kariyawasam, Subhashinie
Institutions
University of Florida
Start date
2020
End date
2025
Objective
The overarching goal of the proposed study is to minimize the losses to the table egg industry due to C. hepaticus-associated Spotty Liver Disease (SLD) through vaccination. To achieve this goal, we have formulated the following three objectives:1. Identify immunodominant mimitopes by screening the phage display library with hyperimmune sera raised against C. hepaticus2. Creation of recombinant mimotope-expressing E. coli3. Assess the efficacy of the selected mimotope/s against a challenge of C. hepaticus
Funding Source
Nat'l. Inst. of Food and Agriculture
Project source
View this project
Project number
FLA-VME-005986
Accession number
1023600
Categories
Campylobacter