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Allergen Specific Antibody Binding Characteristics and Longitudinal Serological Changes to Purified Allergens

Institutions
St. Mary's Hospital, Manchester
Start date
2000
End date
2001
Objective
This project aims to examine the role that affinity/avidity (strength/quality) of antibody binding to major peanut allergens has in the persistence of peanut allergy.
More information
Unlike many food allergies, which are common in infancy, peanut allergy persists into adulthood, and multiple factors may be responsible for this, such as the strength or quality of antibody binding to peanut allergen(s).

A group of 70 peanut allergic individuals will be followed for a period of two to five years. Levels and the affinities of total and peanut-specific antibodies in blood will be examined over this period.

Find more about this project and other FSA food safety-related projects at the Food Standards Agency Research webpage.

Funding Source
Food Standards Agency
Project number
T07018
Commodities
Nuts, Seeds