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Assess the Role of Actin Pedestal Formation in Intestinal Colonization by EHEC and the Induction of Tissue Damage during Infection

Investigators
Tzipori, Saul
Institutions
Tufts University
Start date
2005
End date
2006
Objective
The NIAID research agenda in Food and Waterborne Diseases will be implemented at the direction of the Project Officer. This inter-disciplinary consortium will address food and waterborne pathogens (bacteria, viruses, and protozoa) included in the NIAID Category A, B, C priority organisms list.
More information
Non-Technical Summary: The ability to quickly diagnose and treat food- and water-borne pathogens is of paramount importance. This research will play a critical role in protecting the country from bioterrorist threats. We will establish a Microbiology Research Unit (MRU) in the Food & Waterborne Diseases (FWD) Integrated Research Network (IRN).

Approach: The FWD IRN will 1) evaluate vaccines, therapeutics, and rapid detection methods; 2) integrate human mucosal immunity with clinical research; 3) increase research and product development activities; and, 4) include the ecology and microbiology of food- and water-borne diseases as well as drug resistant pathogens.

Funding Source
Nat'l. Inst. of Food and Agriculture
Project source
View this project
Project number
MASV-SUB371
Accession number
205706
Categories
Bacterial Pathogens
Parasites
Natural Toxins
Viruses and Prions
Chemical Contaminants
Antimicrobial Resistance