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Ca: National Animal Health Laboratory Network

Investigators
Crossley, Beate
Institutions
University of California - Davis
Start date
2009
End date
2013
Objective
CAHFS is an active member of the NAHLN, fully committed to providing enhanced diagnostic capability and capacity in order to strengthen the nation's animal health and agricultural economy. As a participating NAHLN laboratory, CAHFS will provide educational outreach and training for disease diagnostics and quality assurance, expand national laboratory testing capacity, improve and validate diagnostic technologies and laboratory information management systems, and provide related laboratory expertise for animal disease response activities within the United States. CAHFS will support national surveillance and diagnostics by providing technical expertise and critical laboratory infrastructure for USDA programs including AI, END, BSE, and CSF, as well as for emerging diseases and/or new programs as they are identified by USDA program staff. Critical to these activities will be the ongoing enhancement of laboratory quality assurance, assay development and validation, equipment platform review, Select Agent program participation, and preparedness for emergency disease response involvement. CAHFS is dedicated to enhancing the NAHLN in early detection and rapid laboratory response following introduction of an animal disease agent, whether a naturally occurring or an intentional disease event, in order to facilitate rapid and appropriate recovery from a potential animal agriculture catastrophe in the U.S.
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NON-TECHNICAL SUMMARY:
The individual member diagnostic laboratories in the NAHLN provide critical and enhanced diagnostic capabilities and capacity in order to help protect and strengthen the nation?s animal health and agricultural economies, food safety and public health.

APPROACH:
The CAHFS laboratory will support the NAHLN in educational outreach, technical development, and diagnostic laboratory support. CAHFS will provide outreach to industry, veterinary professionals, partner diagnostic laboratories, students, and animal health stakeholders through use of newsletters, web sites and other written materials, courses, and technical presentations. NAHLN activities and the associated role in animal health emergency response activities will be presented to relevant partners and agencies throughout the granting period. CAHFS will provide facilities and technical expertise for tabletop exercises that involve NAHLN partners, first-responders, and allied animal health partners. CAHFS will coordinate with AAVLD to provide NAHLN laboratory audit training and will participate in Quality Symposia and NAHLN-related quality management activities. CAHFS will participate in on-site review and pilot data population of quality management software for the continuous evaluation of assay performance and assay validation documentation. CAHFS will work in collaboration with international standards organizations and allied animal health partners to meet the shared data system and networking needs of the NAHLN, and will provide technical and training support to NAHLN IT partners. CAHFS will continue to provide technical capacity and capability for the NAHLN to include active participation in ongoing disease detection, surveillance, assay development and validation programs, as well as timely involvement in new and emerging issues, such as Swine Influenza Virus and vvIBD virus. CAHFS will maintain communication and diagnostic support within the three national laboratory networks: NAHLN, FERN, and LRN. CAHFS will support national preparedness and response planning by maintaining Select Agent registration, staff training, BSL3 facility-use training, and emergency response exercises. Included in that effort, CAHFS will formally review local Situation Reports and Response activities generated from recently emergent threat issues in order to effectively share ""laboratory lessons learned"" and generate additional response flexibility for future NAHLN-related emergency disease responses.

PROGRESS:
2012/08 TO 2013/08
Target Audience: The target audiences are government animal and public health agencies, regulatory agencies, and private industry affiliates in diagnostic medicine. The general public is served by NAHLN activties. Changes/Problems: Nothing Reported What opportunities for training and professional development has the project provided? CAHFS actively supported the NAHLN by providing outreach to veterinary students, veterinarians, animal industries, regulatory partners, academic partners and allied public interests served by the CAHFS. The outreach materials included written and verbal presentations, training, and exercises on the roles, responsibilities and benefits that the NAHLN serves in animal and veterinary public health. Attendance at the foreign animal disease class at Plum Island. How have the results been disseminated to communities of interest? Results have been disseminated through peer-reviewed publications, presentations, tours and client reports. What do you plan to do during the next reporting period to accomplish the goals? This is the final report.
PROGRESS:
2011/08/15 TO 2012/08/14
OUTPUTS: The CAHFS maintains BSL2 and BSL3 testing capabilities and facilities, as well as trained and competent staff in support of the National Animal Health Laboratory Network. Throughout the review period, CAHFS played a key role in the national surveillance and outbreak response through diagnostic testing and test validation activities with NAHLN partners. In addition to ongoing surveillance and national cohort studies with USDA targeted high-threat pathogens classical swine fever virus, foot-and-mouth disease, rinderpest, African swine fever, avian paramyxovirus-1, including subtyping for exotic Newcastle disease and influenza virus including subtyping of the most important of all of the high impact subtypes. The CAHFS has been actively involved in detection and response to emerging disease threats within the livestock and poultry industries (e.g., vvIBDV). During the review period, CAHFS was a collaborator in multiple NAHLN partner activities such as participation in a lateral flow ELISA detection for foot and mouth disease virus in tissue samples and participation in the inter-laboratory comparison for foot and mouth disease virus detection in milk samples. CAHFS is also a valuable member in the CDC Laboratory Response Network, the Food Emergency Response Network, the Integrated Consortium of Laboratory Networks, the Veterinary Laboratory Response Network and the National Select Agent Program. CAHFS actively supports the NAHLN by providing outreach to veterinary students, veterinarians, animal industries, regulatory partners, academic partners and allied public interest. The outreach materials include written and verbal communications, training, and exercises on the roles, responsibilities and benefits that the NAHLN serves in animal and veterinary public health. The CAHFS continued participation with the NAHLN in the development and deployment of national diagnostic data reporting and networking activities through training and technical support, as well as through active use and validation of laboratory information management and communication standards; e.g., FoodShield. PARTICIPANTS: Partners include USDA APHIS, USDA NIFA, the California Department of Food and Agriculture, USDA Wildlife Services, California Department of Fish and Game, the livestock and poultry industries that utilize the CAHFS laboratory system, commercial industry and academic partners. TARGET AUDIENCES: The target audiences are government animal and public health agencies, regulatory agencies, and private industry affiliates in diagnostic medicine. The general public is served by NAHLN activities. PROJECT MODIFICATIONS: Nothing significant to report during this reporting period.
PROGRESS:
2010/08/15 TO 2011/08/14
OUTPUTS: The CAHFS maintains BSL2 and BSL3 testing capabilities and facilities, as well as trained and competent staff in support of the National Animal Health Laboratory Network. Throughout the review period, CAHFS played a key role in the national surveillance and outbreak response through diagnostic testing, and test validation activities with NAHLN partners. In addition to ongoing surveillance and national cohort studies for USDA targeted high-threat pathogens classical swine fever virus, foot-and-mouth disease, rinderpest, African swine fever, influenza virus, and exotic Newcastle disease, the CAHFS was actively involved in detection and response to emerging disease threats within the livestock and poultry industries (e.g., vvIBDV). During the review period CAHFS was a collaborator in multiple NAHLN partner activities, including the CDC Laboratory Response Network, the Food Emergency Response Network, the Integrated Consortium of Laboratory Networks, and the National Select Agent Program. CAHFS actively supported the NAHLN by providing outreach to veterinary students, veterinarians, animal industries, regulatory partners, academic partners and allied public interests served by the CAHFS. The outreach materials included written and verbal presentations, training, and exercises on the roles, responsibilities and benefits that the NAHLN serves in animal and veterinary public health. The CAHFS additionally participated with the NAHLN in development and deployment of national diagnostic data reporting and networking activities through training and technical support, as well as through active use and validation of laboratory information management and communication standards; e.g., FoodShield. PARTICIPANTS: Partners include USDA APHIS, USDA NIFA, the California Department of Food and Agriculture, USDA Wildlife Services, California Department of Fish and Game, the livestock and poultry industries that utilize the CAHFS laboratory system, commercial industry and academic partners. TARGET AUDIENCES: The target audiences are government animal and public health agencies, regulatory agencies, and private industry affiliates in diagnostic medicine. The general public is served by NAHLN activities. PROJECT MODIFICATIONS: Nothing significant to report during this reporting period.
PROGRESS:
2009/08/15 TO 2010/08/14
OUTPUTS: The CAHFS maintains BSL2+ and BSL3 testing capabilities and facilities, as well as trained and competent staff in support of the National Animal Health Laboratory Network. Throughout the review period, CAHFS played a key role in national surveillance and outbreak response through diagnostic testing, assay development, and test validation activities with NAHLN partners. In addition to ongoing surveillance for USDA targeted high-threat pathogens, including H5 avian influenza virus, the CAHFS was actively involved detection and response to emerging disease threats within the livestock and poultry industries (e.g. vvIBDV). CAHFS was an early participant in the national response following detection of the novel H1N1 swine influenza virus in 2009, including the first reported detection of that virus in an exotic cat. During the review period CAHFS was a collaborator in multiple NAHLN partner activities, including the CDC Laboratory Response Network, the Food Emergency Response Network, and the National Select Agent Program. CAHFS actively supported the NAHLN by providing outreach to veterinarians, animal industries, regulatory partners, academic partners, and allied public interests served by the CAHFS. The outreach materials included written and verbal presentations, training, and exercises on the roles, responsibilities, and benefits that the NAHLN serves in animal and veterinary public health. The CAHFS additionally participated with the NAHLN in development and deployment of national diagnostic data reporting and networking activities through training and technical support, as well as through active use and validation of laboratory information management and communication standards. PARTICIPANTS: Partners include USDA APHIS, USDA NIFA, the California Department of Food and Agriculture, USDA Wildlife Services, California Department of Fish and Game, the livestock and poultry industries that utilize the CAHFS laboratory, commercial industry, and academic partners. TARGET AUDIENCES: The target audiences are government animal and public health agencies, regulatory agencies, and private industry affiliates in diagnostic medicine. The general public is served by NAHLN activities. PROJECT MODIFICATIONS: Nothing significant to report during this reporting period.

Funding Source
Nat'l. Inst. of Food and Agriculture
Project source
View this project
Project number
CALV-CAHFS-NAHLM
Accession number
218959
Categories
Bacterial Pathogens
Commodities
Produce