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Characterization of Plasmid-Associated Antimicrobial Resistance in Salmonella enterica Serovars Associated with Poultry and Human infections

Foley, Steven
DHHS/FDA - National Center for Toxicological Research
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  1. Identify and understand the genetic mechanisms associated with plasmids that facilitate the spread and persistence of virulence and multidrug in Salmonella from poultry-and-egg- associated serovars.
  2. Sequence the plasmids from multidrug-resistant S. enterica serovar Enteritidis, Heidelberg, and Typhimurium strains to identify genes likely associated with virulence and antimicrobial resistance.
  3. Determine the relative selective potential of antimicrobial agents to trigger the dissemination of antimicrobial resistance and virulence factors to susceptible Salmonella.
  4. Determine the contribution of plasmids transferred via conjugation to virulence in Salmonella strains


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Responsible Division: Microbiology
Funding Source
Nat'l. Center For Toxicological Research
Project source
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Project number
Antimicrobial Resistance
Bacterial Pathogens
Meat, Poultry, Game