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Co-Display of Hemagglutinin and CD154 on the Surface of Yeast Cells as a Vaccine Against Avian Influenza

Investigators
Hart, Mark
Institutions
DHHS/FDA - National Center for Toxicological Research
Objective

  1. Generate HA surface-presented yeast recombinant avian influenza vaccines.
  2. Characterize humoral and cellular-mediated immune responses of yeast vaccines in mice.
  3. Demonstrate protection of mice from lethal avian-influenza virus through yeast-based immunization.
More information
Responsible Division: Microbiology
Funding Source
Nat'l. Center For Toxicological Research
Project source
View this project
Project number
E0733301
Categories
Viruses and Prions
Parasites
Natural Toxins
Bacterial Pathogens
Chemical Contaminants