- Institutions
- Centre for Environment, Fisheries and Aquaculture Sciences (CEFAS)
- Start date
- 2004
- End date
- 2004
- Objective
- This research project aims to examine the potential cytotoxicity of cockle extract that gives rise to the atypical response in the diarrhetic shellfish poisoning (DSP) mouse bioassay (MBA).
This research project aims to examine, using conventional cell-based assays, any potential cytotoxicity of cockle extracts that gives rise to the atypical response in the DSP assay.
The study will determine cytotoxicity by investigating whether the cockle extracts adversely affect the capacity of cells to function normally, degrade cell membranes and/or initiate programmed cell death.
- More information
- Since June 2001, atypical responses have been observed during the diarrhetic shellfish poisoning (DSP) mouse bioassay (MBA) used within the UK statutory biotoxin monitoring programme.
These have occurred primarily from cockles from England, Wales and Northern Ireland, but also from small numbers of mussels from England and Wales.
This project will examine the potential cytotoxicity of cockle extract that give rise to the atypical response in the DSP MBA.
Find more about this project and other FSA food safety-related projects at the Food Standards Agency Research webpage.
- Funding Source
- Food Standards Agency
- Project number
- B16006
- Categories
- Natural Toxins
- Commodities
- Seafood
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