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Control of Toxic Endophytic Fungi with Bacterial Endophytes and Regulation of Bacterial Metabolites for Novel Uses in Food Safety

Investigators
Glenn, Anthony (Tony)
Institutions
USDA - Agricultural Research Service
Start date
2011
End date
2016
Objective
1. Determine the potential and genetic mechanisms involved in horizontal gene transfer from Gram-negative pathogenic bacteria to a plant friendly Gram-positive bacterial endophyte Bacillus mojavensis affecting its use as a desirable biocontrol potential. 2. Determine the diversity, evolution, and function of bacterial endophytes in cornfield environments and their impact on the metabolic activity of Fusarium verticillioides, including the production of mycotoxins as well as the detoxification/inactivation of xenobiotic compounds. 3. Determine how the biocontrol organisms can be effectively utilized to prevent the accumulation of the fumonisins; specifically the enhancement of plant defense strategies and production of the antifungal agent surfactin by Bacillus mojavensis.
Funding Source
Agricultural Research Service
Project source
View this project
Project number
6040-42000-042-00D
Accession number
421722
Categories
Parasites
Natural Toxins
Viruses and Prions
Bacterial Pathogens
Chemical Contaminants
Mycotoxins