An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Controlling Egg Contamination with Salmonella Enterica by Understanding its Evolution and Pathobiology

Investigators
Gast, Richard; Bouldin, Jean Guard; Guard, Jean
Institutions
USDA - Agricultural Research Service
Start date
2006
End date
2011
Objective
The objectives of this proposed research will be to identify naturally occurring genetic variation in Salmonella enterica that correlates with the evolution of egg contamination and enhanced growth of the bacterium in the hen, the egg and in the on- farm environment and to then determine how different genetically defined strains vary in their pathobiology within the hen and how these differences affect the risk of egg contamination and the control of disease.
More information
Approach: Our approach will be to identify single nucleotide polymorphisms (SNPs) that occur naturally in the genome of Salmonella enterica, link them to the phenotypic attributes of the pathogen that are relevant to causation of egg contamination and growth to high cell density, and develop a phylogenetic database that aids cost effective screening of the Salmonellae for these traits. We will then characterize the processes by which bacteria are deposited inside eggs laid by infected laying hens and assess the significance of these processes for proposed cost effective and feasible disease control measures such as egg refrigeration, diagnostic egg culturing, and assay of shell quality.
Funding Source
Agricultural Research Service
Project number
6612-32000-004-00
Accession number
410732
Categories
Salmonella
Bacterial Pathogens
Commodities
Meat, Poultry, Game
Eggs