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Detection of BSE Prions from Cattle and Sheep using Transgenic Mice and Conformation-Dependent Immunoassay

Institutions
University of California - San Francisco
Start date
2003
End date
2006
Objective
This research project aims to improve methods for the detection of BSE infection in cattle and sheep including differentiation between BSE and scrapie infection in sheep.
More information
The aim of this joint FSA/ Defra study is to further characterise two complementary methods for detection of and discrimination between BSE and scrapie prions.

These two methods are bioassay using transgenic mice expressing bovine prion protein (Tg(BoPrP) and the in vitro Confirmation-Dependent Immunoassay (CDI).

Find more about this project and other FSA food safety-related projects at the Food Standards Agency Research webpage.

Funding Source
Food Standards Agency
Project number
M03034
Categories
Viruses and Prions