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Determination of Amoxicillin and Lincomycin Incurred Residues in Salmon and Tilapia for Selection of FDA Method Trial Study Materials

Investigators
Ang, Catharina
Institutions
DHHS/FDA - National Center for Toxicological Research
Objective
Amoxicillin and lincomycin have been identified as having toxicological significanceby the CVM, NCTR, and the U.S. Department of Agriculture (USDA) and have been scheduled for incurred-residue FDA method trials. Methods of analysis have been developed and validated for amoxicillin in catfish and salmon and lincomycin in salmon.
  1. Validation of the above methods for incurred residues of amoxicillin in salmon and tilapia and lincomycin in salmon are needed.
  2. Documentation of incurred-residue confirmation methods by Liquid Chromatography/Mass Spectrometry (LC/MS) are also needed for these regulatory methods.
More information
FY 2000 Accomplishments: One manuscript related to this work has been published under E0693611.
FY 2001 Plans:The final phases of E0693601 and E0693611 (methods development) represent theinter-laboratory collaboration to evaluate the ruggedness of these analytic techniques.
Funding Source
Nat'l. Center For Toxicological Research
Project number
P00423
Categories
Natural Toxins
Chemical Contaminants
Commodities
Seafood