An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Development and validation of oil based antimicrobial delivery systems for dry cleaning and sanitation of food processing equipment

Investigators
McLandsborough, Lynne
Institutions
University of Massachusetts
Start date
2020
End date
2024
Objective
The overall goal of this study is to develop and validate oil-based antimicrobial delivery systems for dry cleaning and sanitation of food processing equipment. This proposal hypothesizes that oil-based delivery system will be an effective means to deliver antimicrobial organic acids and essential oils to non-growing bacteria for clean-in-place applications. The objectives are as follows:· Objective 1. Develop and test oil-based antimicrobials to destroy bacteria non-water based (dry) cleaning and sanitation of food processing equipment. A rapid screening method will be developed to screen desiccated cells against the formulated oil-based antimicrobial solutions. Oil-based antimicrobial solutions will be formulated with organic acids delivery or water-in-oil emulsions containing traditional sanitizing agents.· Objective 2. Validate the effectiveness of oil-based antimicrobials in a bench-top clean-in-place system. A bench-top clean-in-place system will be developed to evaluate the efficacy of the developed oil-based antimicrobials against Salmonella in the presence of peanut butter.· Objective 3. Investigate the mechanisms of oil-based antimicrobials. Microscopy will be used with a combination of fluorescent stains to assess the influence of oil-based antimicrobials on membrane disruption, cellular respiration, protein translation, and membrane viscosity.
Funding Source
Nat'l. Inst. of Food and Agriculture
Project source
View this project
Project number
MASW-2019-06929
Accession number
1021736
Categories
Salmonella
Parasites
Natural Toxins
Viruses and Prions
Bacterial Pathogens
Chemical Contaminants
Commodities
Nuts, Seeds