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Development of Cost-Effective Biomarkers for Herbicides and Fungicides

Institutions
Health and Safety Laboratory, Derbyshire UK
Start date
2006
End date
2007
Objective
This project aims to develop cost-effective biomarkers of mixed pesticide exposure.

The pesticides have been selected on the basis of their occurrence as residues in food.

The focus of the proposal is to develop methods that are compatible in approach with those being developed under the existing FSA project (T10003).

This will potentially allow a full suite of pesticide biomarkers to be analysed in a single sample using common approaches.

More information
In its report on Risk Assessment of Mixtures of Pesticides and Similar Substances, the Committee on Toxicity of Chemicals in Food Consumer Products and the Environment recommended a need for the development of methods to provide cost-effective biomarkers or other robust indicators of population exposure and body burdens of mixtures of pesticides and relevant veterinary residues.

There are already projects (including two from the Health and Safety Laboratory) focusing on organophosphate and carbamate anticholinesterases.

This proposal addresses biomarker method development for the other pesticides of interest including paraquat/diquat, triazole fungicides, conazoles and pyrethroids.

Find more about this project and other FSA food safety-related projects at the Food Standards Agency Research webpage.

Funding Source
Food Standards Agency
Project number
T10013
Categories
Risk Assessment, Management, and Communication
Natural Toxins
Sanitation and Quality Standards