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EFFORT - Ecology from Farm to Fork of Microbial Drug Resistance and Transmission

Investigators
Wagenaar, Jaap
Institutions
Utrecht University
Start date
2013
End date
2018
Objective
EFFORT studies the complex epidemiology and ecology of antimicrobial resistance and the interactions between bacterial communities, commensals and pathogens in animals, the food chain and the environment. This will be conducted by a combination of epidemiological and ecological studies using newly developed molecular and bio-informatics technologies. EFFORT will include an exposure assessment of humans from animal/environmental sources. The ecological studies on isolates will be verified by in vitro and in vivo studies. Moreover, real-life intervention studies will be conducted aiming at reducing the use of antimicrobials in veterinary practice. Focus will be on understanding the eco-epidemiology of antimicrobial resistance from animal origin and based on this, predicting and limiting the future evolution and exposure to humans of the most clinically important resistance by synthesising different sources of information in our prediction models.

Through its results, the EFFORT research will provide scientific evidence and high quality data that will inform decision makers, the scientific community and other stakeholders about the consequences of AMR in the food chain, in relation to animal health and welfare, food safety and economic aspects. These results can be used to support political decisions and to prioritize risk management options along the food chain.

More information
View more project details
Funding Source
European Commission
Project source
View this project
Project number
613754
Categories
Antimicrobial Resistance
Risk Assessment, Management, and Communication