An official website of the United States government.

The .gov means it’s official.
Federal government websites always use a .gov or .mil domain. Before sharing sensitive information online, make sure you’re on a .gov or .mil site by inspecting your browser’s address (or “location”) bar.

This site is also protected by an SSL (Secure Sockets Layer) certificate that’s been signed by the U.S. government. The https:// means all transmitted data is encrypted — in other words, any information or browsing history that you provide is transmitted securely.

Environmental Chemical Residues and Their Impact in The Food Supply

Investigators
Shelver, Weilin; Lupton, Sara; Hakk, Heldur
Institutions
USDA - Agricultural Research Service
Start date
2016
End date
2021
Objective

Objective 1: Develop and/or validate rapid screening assays for the detection of environmental chemicals relevant to U.S. food production. Sub-objective 1.A: Development of immunochemically based rapid screening methods for new and emerging persistent organic pollutants. Sub-objective 1.B: Development of immunochemical purification methods for new and emerging persistent organic pollutants. Objective 2: Determine levels and sources of dioxins and related compounds in the domestic food supply. Provide food safety agencies with data to confirm or refute the wholesomeness and competitiveness of beef, pork, chickens, turkeys and/or catfish. Sub-objective 2.A: Conduct a nationally-based survey of PCDD/PCDF/PCB/PBDE levels in the domestic meat supply (beef, pork, chicken, turkey, and/or catfish) by collection of adipose tissues from U.S. slaughter facilities. Sub-objective 2.B: Identify potential production-based or environmental sources of PCDDs/PCDFs/PCBs/PBDEs in food-producing animals. Objective 3: Determine the uptake, metabolism (in vitro or in vivo), distribution, excretion, and fate of environmental contaminants with the goal of developing pharmacokinetic rate and volume constants pertinent to residue depletion, selection of marker compounds, and calculation of withdrawal intervals. Sub-objective 3.A: Characterize the absorption, disposition, metabolism, and excretion (ADME) of POPs in food animals. Sub-objective 3.B: Identify cellular fractions and enzyme classes responsible for the metabolism and putative dehalogenation of POPs. Sub-objective 3.C: Characterize the bioavailability of POPs in animal systems from major exposure routes. Sub-objective 3.D: Determine the fate and transport of POPs through soil during ambient weather conditions. Sub-objective 3.E: Determine the effect of milk processing on POP concentrations in finished products.

Funding Source
Agricultural Research Service
ARS (NP108)
Project source
View this project
Project number
3060-32420-002-00D
Accession number
430496
Categories
Chemical Contaminants
Food Defense and Integrity
Parasites
Natural Toxins
Viruses and Prions
Bacterial Pathogens
Commodities
Meat, Poultry, Game