An official website of the United States government.

The .gov means it’s official.
Federal government websites always use a .gov or .mil domain. Before sharing sensitive information online, make sure you’re on a .gov or .mil site by inspecting your browser’s address (or “location”) bar.

This site is also protected by an SSL (Secure Sockets Layer) certificate that’s been signed by the U.S. government. The https:// means all transmitted data is encrypted — in other words, any information or browsing history that you provide is transmitted securely.

Evaluation of Fecal Salmonella Carriage in Symptomatic and Asymptomatic Dogs in T

Investigators
Baszler, Timothy
Institutions
Washington State University
Start date
2011
End date
2013
Objective

Project Summary: The purpose of this project is to determine whether or not there are qualitative and quantitative differences in fecal Salmonella colonization between symptomatic and asymptomatic dogs in the Pacific Northwest region of the USA. Salmonellosis is one of the most important food-borne diseases and causes substantial medical and economic burden worldwide. Although food is the main source of Salmonella infection in humans, non-food Salmonella sources can include pets (particularly dogs and cats), as well as their foods, snacks, and supplements. The most common symptoms of salmonellosis in humans or animals is gastrointestinal disease and Salmonella bacteria are shed via infected feces. Dogs in particular often do not show signs of salmonellosis when infected. Recent studies show that 14% to 25% of asymptomatic household dogs can shed Salmonella into their environment. Also a recent outbreak of human salmonellosis, primarily in toddlers, was linked to commercial dry dog food. There remains a significant gap in knowledge regarding factors associated with differences in Salmonella carriage between dogs with or without gastrointestinal disease. This proposal will test the hypothesis that dogs with Salmonella-associated gastrointestinal disease have both a higher prevalence of fecal Salmonella colonization than asymptomatic dogs, and higher fecal counts of Salmonella bacteria than asymptomatic dogs with fecal Salmonella. Feces and pet-related management data from a minimum of 150 symptomatic and 150asymptomatic dogs will be collected from dogs presented to the veterinary teaching hospital at Washington State University, College of Veterinary Medicine and private veterinarians from Alaska, Idaho, Montana, Oregon, and Washington. Feces will be cultured for Salmonella using standardized methods from ISO standard 6579:2002 identified to specific serotype, and quantified using conventional most-probable-number (MPN) culture techniques. Results of the study should provide new information regarding prevalence and risk factors for Salmonella colonization in asymptomatic and symptomatic dogs brought to veterinary clinics, and the relationship of bacterial load to gastrointestinal disease.

Funding Source
Food and Drug Administration
Project source
View this project
Project number
1U18FD004317-01
Categories
Salmonella
Bacterial Pathogens
Antimicrobial Resistance