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Genetic Profiles of Bovine-Origin Salmonellae

Investigators
LeJeune, Jeffrey
Institutions
Ohio State University
Start date
2005
End date
2006
Objective
To determine patterns of sequence variability (absence of specific genes) among Salmonella frequently isolated from cattle (but infrequently associated with human diseases) and the genetic sequences of highly pathogenic strains of Salmonella.
More information
Findings: Many of the most frequently isolated types of Salmonella found in cattle and ground beef rarely show up as causes of human disease. The reason for this is unknown, but one of the most plausible explanations is that all Salmonella are not equally capable of causing disease. In other words, some organisms, although they are classified as �salmonella� pose little threat to health individually-�sheep in wolves� clothing.� By comparing the DNA of Salmonella isolates from humans, cattle, and beef, it will be possible to develop specific genetic markers for Salmonella and predict which organisms should receive the most attention.
Funding Source
Nat'l. Cattlemen's Beef Assoc.
Project number
BC-2005-15
Categories
Bacterial Pathogens
Sanitation and Quality Standards
Salmonella