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Mechanism of Secretion Activation in the Shigella TTSS

Institutions
University of Oxford
Start date
2005
End date
2008
Objective
Gram-negative bacteria commonly interact with eukaryotic host cells by using type III secretion systems (TTSSs or secretons). TTSSs serve to inject bacterial proteins directly into the host cell membrane and cytoplasm during infection.
Project number
G0401595
Categories
Bacterial Pathogens
Shigella