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Method Performance Verification for the Analysis of Minor Clam Species for Paralytic Shellfish Poisoning Toxins

Institutions
Centre for Environment, Fisheries and Aquaculture Sciences (CEFAS)
Start date
2011
End date
2011
Objective

The AOAC HPLC method 2005.06, which involves the acetic acid extraction of shellfish prior to clean up, derivatisation and HPLC analyses, was subjected to a method performance verification exercise at Cefas for four further clam species of UK commercial significance: (surf, manila, carpet shell and otter clams). Checks followed guidance from the AOAC including an assessment of method selectivity, sensitivity, recovery, precision and uncertainty of measurement. Performance checks were conducted on the major PSP toxins commercially available as standards and more commonly found in UK samples.

More information

Background: The mouse bioassay (MBA) is the official reference method for determination of PSP toxins (PSTs) in bivalve shellfish. However, in recent years the AOAC HPLC method 2005.06 has become an approved alternative Official Method by the European Commission and has already been validated and implemented into the UK official control monitoring programme for mussels, cockles, razors and hard clams.

Funding Source
Food Standards Agency
Project source
View this project
Project number
FS235002b
Categories
Natural Toxins
Commodities
Seafood