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Modification of the Ribosomal Target to Enhance Resistance to Trichothecene Mycotoxins

Investigators
Walker-Simmons, M. Kay
Institutions
Rutgers University
USDA - Agricultural Research Service
Start date
2006
End date
2009
Objective
Identify mutations in L3 that confer resistance to DON and determine if FHB resistance can be engineered in transgenic wheat plants by expressing DON resistant L3 genes.
More information
Approach: Characterize expression of the DON resistant L3 genes in transgenic wheat plants and determine if they will confer resistance to FHB. Analyze expression of PAP and L3delta in co-transformed wheat lines and determine if combination of these genes confers better resistance to FHB. Isolate DON resistant alleles of the wheat L3 genes for transformation into wheat.
Funding Source
Agricultural Research Service
Project number
0500-00053-002-58G
Accession number
410637
Categories
Mycotoxins
Natural Toxins