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MOLECULAR ANALYSIS OF SALMONELLA VIRULENCE, ANTIBIOTIC RESISTANCE, AND HOST RESPONSE

Investigators
Bearson, Shawn
Institutions
USDA - Agricultural Research Service
Start date
2005
End date
2010
Objective
(1) Investigate the molecular mechanisms that coordinate virulence and antibiotic resistance in Salmonella obtained from cattle (DT104 and S. dublin) and swine (DT104 and S. choleraesuis). (2) Characterize the molecular mechanisms involved in Salmonella survival, colonization and pathogenicity in relation to various host (swine and cattle) factors such as stress, gastric pH, and protozoa. (3) Investigate the molecular basis for swine resistance to Salmonella colonization by characterizing the immunological aspects of infection.
Funding Source
Agricultural Research Service
Project source
View this project
Project number
3625-32000-078-00D
Accession number
409771
Categories
Salmonella
Antimicrobial Resistance
Viruses and Prions
Bacterial Pathogens