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Neurodevelopmental Effect of Early Life Arsenic Exposure

Investigators
Muzamdar, Maitreyi
Institutions
Children's Hospital - Boston
Start date
2009
End date
2014
Objective
The proposed Career Development Plan incorporates a multi-disciplinary program designed to provide an intense, closely mentored, patient-oriented research experience, associated with a comprehensively structured didactic curriculum in environmental epidemiology, exposure assessment, advanced biostatistics, and risk assessment. Under the mentorship of Dr. David Christiani, Professor of Environmental Health at the Harvard School of Public Health, the candidate will investigate the effect of prenatal and early childhood arsenic exposure on neurodevelopment of children in Bangladesh, a country with high levels of arsenic contamination in groundwater.

This research will examine epidemiological associations of arsenic exposure with measures of neurological development In infants and children, including 1) head circumference, 2) hearing impairment, 3) motor dysfunction, and 4) formal neurocognitive testing.

The studies will be conducted in a cohort of 600 infants who are participating in a current study of reproductive health effects of arsenic. Additional children between the ages of 12 and 24 months will also be recruited neurodevelopmental assessment.

More information
For additional information, including history, sub-projects, results and publications, if available, visit the Project Information web page at the National Institutes of Health Research Portfolio Online Reporting Tool (RePORTER) database.
Funding Source
Nat'l. Inst. of Environmental Health Sciences
Project source
View this project
Project number
1K23ES017437-01
Categories
Sanitation and Quality Standards
Heavy Metals
Prevention and Control
Risk Assessment, Management, and Communication