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Quantification Proteomic, Transcriptomic, and Phenotypic Microarray Analysis of C. Jejuni for the Identification of Colonization Factors in Poultry

Investigators
Sung, Kidon
Institutions
DHHS/FDA - National Center for Toxicological Research
Objective

  1. Evaluate genomic and phenotypic microarrays, and whole proteomic analyses to compare genes, phenotypes, and proteins from both good and poor C. Jejuni chicken colonizers.
  2. Investigate functional role of identified colonizing factors by mutant construction, in vitro assays, and in vivo assays.
  3. Identify potential targets for vaccine that will enable us to eliminate the threat of Campylobacter infection in chickens.
More information
Responsible Division: Microbiology
Funding Source
Nat'l. Center For Toxicological Research
Project source
View this project
Project number
E0735601
Categories
Bacterial Pathogens
Campylobacter
Commodities
Meat, Poultry, Game