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Quantitative Evaluation of Selective Factors Impacting the Development, Amplification, Persistence, and Transfer of Resistance in Pig Flora

Investigators
Anderson, Robin
Institutions
USDA - Agricultural Research Service
Start date
2005
End date
2006
Objective
To quantitatively model the effects of therapeutic and sub-therapeutic tylosin administration on the development, amplification, persistence, and transfer of genetic elements conferring macrolide resistance within mixed populations of commensal and pathogenic gut bacteria grown in continuous-flow culture.
More information
Approach: Commensal and foodborne pathogenic gut bacteria will be grown under conditions of sub-therapeutic and therapeutic tylosin use. Samples removed from the populations will be tested using cultural and molecular techniques to determine phenotypic and genotypic antimicrobial resistance characteristics.
Funding Source
Agricultural Research Service
Project number
6202-32000-020-23T
Accession number
410287
Categories
Bacterial Pathogens
Antimicrobial Resistance
Commodities
Meat, Poultry, Game