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Reducing Production Losses Due to Oxidative Stress and Bacterial Pathogens in Swine

Investigators
Hatfield, Jerry; Kerr, Brian; Bearson, Shawn
Institutions
USDA - Agricultural Research Service
Start date
2017
End date
2022
Objective
The objectives of the project are to develop an understanding of the interrelationships between non-antibiotic feed additives and pathogen translocation and shedding in growing pigs, obtain critical measures of oxidative stress in growing pigs and reproducing swine, and develop interventions to reduce or prevent pathogen colonization and disease in swine in an effort to maximize production efficiency but minimize environmental impact. Objective 1: Evaluate alternatives to antibiotics (butyric acid, resistant starch, inulin, etc.) for maintaining growth performance and reducing intestinal bacterial translocation and shedding in growing pigs. Objective 2: Determine the inherent variation in oxidative stress measures in breeding and lactating gilts, and correlate to measures of sow lifetime productivity. Objective 3: Identify markers associated with oxidative stress and correlate to changes in pig growth and feed intake, using peroxidized soybean oil as the inducer of oxidative stress. Objective 4: Determine whether vaccination of swine with a Salmonella DIVA vaccine can prevent/reduce colonization and improve growth following transmission of Salmonella from actively shedding pigs.
Funding Source
Agricultural Research Service
Project source
View this project
Project number
5030-31000-006-00D
Accession number
433200
Categories
Pesticide Residues
Commodities
Nuts, Seeds