Research Projects Database Search | National Agricultural Library

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National Agricultural Library

U.S. Department of Agriculture

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Displaying projects 1 - 25 of 40

Origin and Mechanism of Promiscuous Prion Strains

Investigators

Supattapone, Surachai

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2003

End date

2016
REPLICATION MECHANISM OF HUMAN PRIONS

Investigators

Safar, Jiri; Surewicz, Witold K

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2011

End date

2017
REPLICATION MECHANISM OF HUMAN PRIONS

Investigators

Safar, Jiri; Surewicz, Witold K

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2018

End date

2023
MECHANISMS OF PRION SPREAD AND ESTABLISHMENT OF INFECTION

Investigators

Mathiason, Candace K.; Kincaid, Anthony; Bartz, Jason

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2018

End date

2023
DISSECTING THE MECHANISM OF PRION FORMATION WITH A PERMISSIVE HOST

Investigators

Supattapone, Surachai

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2018

End date

2022
MOLECULAR BASIS OF SPONGIFORM ENCEPHALOPATHY IN PRION DISEASE

Investigators

Sigurdson, Christina

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2018

End date

2020
MECHANISMS OF PRION STRAIN DYNAMICS

Investigators

Bartz, Jason

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2018

End date

2023
CHARACTERIZING THE STRAIN AND HOST RANGE PROPERTIES OF PRIONS CAUSING EMERGENT FORMS OF CHRONIC WASTING DISEASE

Investigators

Telling, Glenn C

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2018

End date

2023
GASTROINTESTINAL MICROBIOME AND STROKE OUTCOMES NETWORK (GEMSTONE)

Investigators

Worrall, Bradford B; Sale, Michele M

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2018

End date

2020
GENOMIC AND PROTEOMIC ANALYSIS OF PRION SYNAPTOTOXICITY

Investigators

Harris, David

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2018

End date

2020
PROBING PRION CLEARANCE THROUGH INTERSTITIAL FLUID AND PERIVASCULAR PATHWAYS

Investigators

Sigurdson, Christina

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2018

End date

2020
Regulatory T cell responses in T. gondii infection of the brain

Investigators

Harris, Tajie Heartsong

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2019

End date

2020
Key Molecular Mechanisms of Extraneural Pathogenesis and Transmission of TSES

Investigators

Zabel, Mark

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2008

End date

2013
Impact of Microparticles on Oral TSE Infections

Investigators

Aiken, Judd

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2008

End date

2013
Host Cell Influences on the Development of Toxoplasmic Encephalitis

Investigators

Koshy, Anita

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2009

End date

2014
Characteristics of Prion Entry and Neuroinvasion Following Nasal Cavity Infection

Investigators

Kincaid, Anthony

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2009

End date

2014
Sensitive ImmunoPCR of Blood-Borne Prions

Investigators

Stevens, Elliot

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2009

End date

2010
High Throughput Screen to Identify Inhibitors of Salmonella Invasion

Investigators

Sacks, David

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2009

End date

2011
Ion Channel Modulation by the Prion Protein: A Novel Toxic Mechanism

Investigators

Harris, David

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2010

End date

2015
Biochemistry of Infectious Prions

Investigators

Supattapone, Surachai

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2007

End date

2012
Development of a Small Molecule Screen for PHOP Regulon Inhibitors in Salmonella

Investigators

Harris, Jason

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2007

End date

2010
Molecular Basis of Cell-Specific Prion Strain Propagation

Investigators

Weissmann, Charles

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2007

End date

2011
An Improved Expression Vector to Create Transgenic Mice for Prion Research

Investigators

Tamguney, Gultekin

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2007

End date

2008
Neuroimaging of Genetically-Defined Incipient CID

Investigators

Prohovnik, Isak

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2005

End date

2007
Inhibitors of Yersinia YOP Type III Secretion (RMI)

Investigators

Mecsas, Joan

Funding Source

Nat'l. Inst. of Neurological Disorders and Stroke

Start date

2005

End date

2007