An official website of the United States government.
- Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
Research Projects Database Search
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Displaying projects 1 - 25 of 96
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to stimulate the development of a new therapeutic for cryptosporidium -
to establish a national surveillance system for enteric fever in India - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2017
- End date
- 2019
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to estimate the burden and severity of invasive Salmonella infections in Moshi, Tanzania - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
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to support late preclinical and early clinical development of a novel treatment for cryptosporidiosis - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
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to evaluate effectiveness and impact of typhoid conjugate vaccine introduction program in Navi Mumbai, India - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2017
- End date
- 2019
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to identify natural compounds in human milk that protect infants from environmental enteric disease and diarrhea - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2017
- End date
- 2019
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to identify the transmission patterns of Cryptosporidium, a leading cause of diarrhea in young children, in Bangladesh - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2015
- End date
- 2017
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to compare the virulence of wild type S. Typhi with that of a toxin-defective mutant in a human volunteer model of S. Typhi infection - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2015
- End date
- 2017
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to evaluate the performance of typhoid diagnostics in a confined population, during an outbreak of typhoid in Zomba and Malosa, Malawi. - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
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to determine if an approved drug product for another indication will demonstrate efficacy in humans to treat diarrhea caused by Cryptospordidium - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2017
- End date
- 2019
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to understand typhoid transmission dynamics in a highly endemic setting in Kenya, thereby informing effective prevention strategies, including vaccination - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
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to determine the prevalence of cryptosporidium infection among adults with HIV infection using a rapid diagnostic stool test in order to design a therapeutic intervention study - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
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to complete a study and publication on the evidence for the currently used definition of diarrhea, as well as systematic reviews related to dehydration and Shigella indications - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2015
- End date
- 2017
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to develop methods to identify environmental reservoirs of S. Typhi, and use these findings to inform targeted intervention strategies for typhoid fever through spatial modeling - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
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to engineer a live vaccine delivery platform that can be given by oral administration to reduce the global diarrheal burden in young children due to infections by enteric pathogens - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
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to determine if vaccination can reduce Campylobacter infection and environmental enteric dysfunction (EED), thereby improving gut health while increasing infant growth trajectories - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
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to determine critical environmental transmission pathways of typhoid in low-income urban areas and design environmental surveillance strategies to monitor typhoid in the environment - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
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to apply highly sensitive quantitative molecular diagnostics for pathogens to understand the etiology of community diarrhea and the relationship and effects of enteropathogens on healthy growth - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2015
- End date
- 2017
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to develop human experimental challenge models in which adult volunteers will be given the protozoan pathogen Cryptosporidium hominis in order to lay a rational foundation for vaccine development - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2015
- End date
- 2017
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to characterize population genetics of Cryptosporidium in children with acute diarrhea and their accompanying caregivers and use molecular techniques to characterize caregiver to child transmission - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2014
- End date
- 2016
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to understand what drives sustained low-level typhoid transmission in Santiago, Chile, where typhoid was once highly endemic, and to use these lessons to assess the feasibility of typhoid elimination - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2017
- End date
- 2019
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to reduce cholera's disease burden in both epidemic and endemic settings through use of evidence-based practices, increased stakeholder collaboration and implementation of renewed strategies for cholera control - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2017
- End date
- 2019
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to systematically compare and analyze a broad range of genomic and transcriptomic datasets to establish up-to-date reference genome sequences and functional annotation for human-infecting Cryptosporidium species - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2016
- End date
- 2018
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to understand what the reservoirs and transmission routes of Non-typhoidal Salmonellae are in sub-Saharan Africa; and how asymptomatic infection of children by Non-typhoidal Salmonellae affects serodiagnostic tests - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2015
- End date
- 2017
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to describe the proportion of hospitalizations from enteric pathogens among hospitalized patients with diarrhea and febrile illness in each of the seven divisions of Bangladesh in order to design wider country wide program - Funding Source
- Bill and Melinda Gates Fndn.
- Start date
- 2015
- End date
- 2017