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SEQC (MACQ-III) - The Sequencing Quality Control Project

Investigators
Su, Zhenqiang
Institutions
DHHS/FDA - National Center for Toxicological Research
DHHS/FDA - Center for Food Safety & Applied Nutrition
DHHS/FDA- Center for Devices and Radiological Health
DHHS/FDA- Center for Drug Evaluation and Research
Objective

  1. Assess different next-generation sequencing (NGS) technologies and various bioinformatics strategies for handling and analyzing the massive sequence datasets by using the reference RNA samples previously established by the MicroArray Quality Control (MAQC) project.
  2. Profile, using NGS technologies, RNA samples isolated from cells with or without treatment by nanoparticles and known toxicants to further evaluate their performance in assessing the safety and toxicity of FDA-regulated products.
More information
Responsible Division: Bioinformatics and Biostatistics
Funding Source
Nat'l. Center For Toxicological Research
Project source
View this project
Project number
E0731901
Categories
Preventive Food Safety Systems
Chemical Contaminants
Sanitation and Quality Standards
Natural Toxins