- Stolle, Andreas
- University of Munich
- Start date
- End date
- To quantify, assess and control PrPsc exposition risk, suitable and reliable methods for detection of high risk material in foodstuff are crucial. A lack of specivity in recently published test systems for CNS material (Locker et al., 1999) is apparent: they are not species specific. All "classical" morphological methods (histological examination with staining, immunohistochemistry) are failing in this field, too. This is due to destruction, alteration and/or masking of the central nervous tissue structures during the production processes of meat products.
The aim of this project is to enable a high level of consumer protection by developing a species specific test system based on markers found specifically in risk material (e.g. central nervous tissue).
To reach this goal, two ways are promising:
- Development of an antibody based test system for detection of species specific differences in amino acid sequence of proteins.
- A system based on detection of mRNA encoding such proteins.
- More information
For more information, please visit the FORPRION Research Program.
- Project number
- LMU 20
- Food Preparation and Handling
- Risk Assessment, Management, and Communication
- Bacterial Pathogens
- Viruses and Prions