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An In Vivo Poultry Model to Study the Effect of Growth Promoters in Resistance to Human Antibiotics in Mixed Bacterial Populations

Institutions
University of Bristol
Start date
2000
End date
2003
Objective
Using chickens as an in vivo model, to determine whether (i) mixed intestinal bacterial populations, including two main anaerobic groups (bacteroides and clostridia), and three facultative anaerobic groups (lactobacilli, enterococci and E. coli) present in the gut flora, will develop resistance to human antibiotics, and (ii) how any resistance to antibiotics is influenced by either, inter-reaction between the bacterial groups, or by shifts in number or types within the bacterial groups or population in the chicken intestinal tract, following exposure to presently used growth promoters.
Funding Source
Dept. for Environment, Food and Rural Affairs
Project number
OD2001
Categories
Escherichia coli
Bacterial Pathogens
Natural Toxins
Commodities
Meat, Poultry, Game