Annals of the New York Academy of Sciences

Tue, 10/08/2019 - 03:22
In this review, we focus on how full‐length chromogranin A and its peptides, including PST, vasostatin‐1, CST, and serpinin, as important modulators of cardiovascular functions, immunometabolism, and cancer. Abstract Chromogranin A (CgA)—the index member of the chromogranin/secretogranin secretory protein family—is ubiquitously distributed in endocrine, neuroendocrine, and immune cells. Elevated...
Wed, 09/25/2019 - 03:21
Whole‐genome sequence analysis was performed on a multidrug‐resistant Providencia rettgeri PR002 clinical strain isolated from the urine of a hospitalized patient in Pretoria, South Africa, in 2013. The array, multiplicity, and diversity of resistance and virulence genes in this strain are concerning, necessitating stringent infection control, antibiotic stewardship and periodic resistance...
Sun, 09/22/2019 - 03:18
We performed a literature search for English research papers, published between 2013 and 2018, reporting on plasmid‐mediated carbapenem resistance. A rise in both carbapenemase types and associated plasmid replicon groups was seen, with China, Canada, and the United States recording a higher increase than other countries. Most reported plasmids were conjugative but not present in multiple...