Diagnostic Microbiology and Infectious Disease

The Research Publications track research that is published across national and international peer-reviewed journals. The most recent articles are available ahead of print and searchable by Journal Title, Subject, USDA Grant Funding Agencies or FDA Grant Funding Agencies. The research publications are tracked across five subject areas: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, and Viruses.

Fri, 02/14/2020 - 03:22
Author(s): Michael A. Pfaller, Cecilia G. Carvalhaes, Caitlin J. Smith, Daniel J. Diekema, Mariana CastanheiraAbstractThe SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSI) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal...
Thu, 01/30/2020 - 03:22
Author(s): Maria Bruna Pasticci, Silvia Bozza, Giuseppe Vittorio De Socio, Abel Frias-Mazuecos, Antonella MencacciAbstractDetection of etiological agents is pivotal for adequate therapy of osteoarticular bacterial infections. Culture often lacks sensitivity, especially in patients under antibiotic therapy. The present study investigates the potential clinical utility of the commercial multiplex...
Fri, 12/20/2019 - 03:22
Author(s): Randal S. Stahl, Bledar Bisha, Sebabrata Mahapatra, Jeffrey C. ChandlerAbstractAntimicrobial resistance is a threat to agricultural production and public health. In this proof-of-concept study, we investigated predicting antimicrobial sensitive/resistant (S/R) phenotypes and host sources of Escherichia coli (n = 128) based on differential fatty acid abundance. Myristic (14:0...
Sat, 12/07/2019 - 03:23
Author(s): Matthew Bankowski, Jason Blanton, Paul Fiorella, Jessy Motes, Nancy Pickens, Jeremy Racicot, Aaron Odegard, Patricia DuBose, Man-Kuang Chang, Charles AbaabaAbstractStaphylococcus epidermidis and a Gram negative bacillus (GNB) were isolated in blood cultures from a 68 year old male with cancer. The GNB was suspicious for Brucella spp., but was identified using 16S rDNA sequencing...
Thu, 11/28/2019 - 03:37
Author(s): Cailin Liu, Chunguang Chen, Yafei Ye, Xiaogai Li, Jingjing Sun, Lijuan Xu, Liang MingAbstractTwo linezolid-resistant and teicoplanin-intermediate Staphylococcus epidermidis strains were isolated from blood cultures in China. The two S.epidermidis strains were methicillin-resistant and showed multidrug-resistance patterns, in addition, population analysis profiling/area under the curve...
Wed, 11/13/2019 - 03:21
Author(s): Patrick M. Redli, Adrian Wanzenried, Jon B. Huder, Christoph Berger, Livia Berlinger, Riccarda Capaul, Jürg Böni, Andrea ZbindenAbstractSapovirus (SaV) and astrovirus (AstV) increasingly are recognized as cause of acute viral gastroenteritis (AGE). We evaluated the real-time RT-PCR assays RIDA®GENE SaV and viral stool panel II (RGN RT-PCR) for detection of SaV, AstV, adenovirus (AdV)...
Sat, 10/26/2019 - 03:29
Author(s): Mustafa Sadek, Laurent Poirel, Patrice NordmannAbstractThis study compared the impact of different approaches, namely non-enrichment, non-selective enrichment, and selective (antibiotic-containing) enrichment steps, for detecting extended-spectrum ß-lactamase producing Enterobacterales (ESBL-E), carbapenemase-producing Enterobacterales (CPE), polymyxin-resistant Enterobacterales (PMR-E...
Sat, 10/26/2019 - 03:29
Author(s): Vaigundan Dhayabaran, Divya Chidambaram, Patnam R. KrishnaswamyAbstractLeptospirosis is a recurring global disease of severe illness involving pulmonary and renal involvement in cattle and humans; that needs attention to cure. The major challenge in treating leptospirosis disease is the diagnosis of the disease. The culturing of an organism is a gold standard for confirmation of the...
Fri, 10/25/2019 - 03:29
Author(s): Tanise Vendruscolo Dalmolin, Alana Mazzetti, Helena Ávila, Julia Kranich, Gabriel Ibrahim Borba Carneiro, Lavinia Nery Villa Stangçer Arend, Guilherme Nardi Becker, Karin Obladen Ferreira, Daiana de Lima-Morales, Afonso Luís Barth, Marcelo PillonettoAbstractRecently it was developed the Colistin Broth Disk Elution test, uses colistin disks as a source of these antibiotics. The aim of...
Tue, 09/24/2019 - 03:25
Author(s): Byron Michael Berenger, Christina Ferrato, Linda ChuiAbstractTransport media are recommended to improve the sensitivity of fecal culture, but there are limited published data comparing bacterial viability in feces stored with or without transport media. In this study, recovery of bacteria from culture-positive feces after 7 days of storage was assessed under the following conditions:...
Tue, 09/24/2019 - 03:25
Author(s): Rafael Antonio Casarin Penha Filho, Joseane Cristina Ferreira, Ana Maria Iba Kanashiro, Angelo Berchieri Junior, Ana Lúcia da Costa DariniAbstractThe number of foodborne gastroenteritis caused by nontyphoidal Salmonella (NTS) worldwide is estimated to be 80.3 million each year. Currently, antimicrobial-resistant NTS disseminated in the animal environment increases the risk of...
Tue, 09/24/2019 - 03:25
Author(s): Matthew M. Hitchcock, Catherine A. Hogan, Indre Budvytiene, Niaz BanaeiAbstractThough the FilmArray GI Panel has a reported aggregate specificity and reproducibility of >97% and > 99%, respectively, the reproducibility is less understood in clinical practice. We measured the reproducibility of positive results for low-prevalence pathogens. Samples with positive results for...
Tue, 09/24/2019 - 03:25
Author(s): I. Sciandra, L. Piccioni, L. Coltella, S. Ranno, G. Giannelli, F. Falasca, G. Antonelli, C. Concato, O. TurrizianiAbstractObjectiveOur purpose was to compare the performance of two recently introduced molecular tests for the identification of gastrointestinal viral infections.Methods100 fecal samples from pediatric patients were analyzed using two workflows, each including nucleic...
Tue, 09/24/2019 - 03:25
Author(s): Mercedeh Tajdar, Marijke Reynders, Mario BerthAbstractHepatitis E virus (HEV) causes worldwide more than 20 million new hepatitis cases yearly. These infections can take on fulminant forms or cause severe extrahepatic manifestations, and integration into hepatitis differential diagnosis is recommended. In developed countries, genotypes 3 and 4 are most common, mainly through zoonotic...
Tue, 09/24/2019 - 03:25
Author(s): Atsushi Hinenoya, Hidetoshi Ichimura, Noritomo Yasuda, Seiya Harada, Kazuhiro Yamada, Masahiro Suzuki, Yoshio Iijima, Akira Nagita, M. John Albert, Noritoshi Hatanaka, Sharda Prasad Awasthi, Shinji YamasakiAbstractMany Escherichia albertii isolates, an emerging pathogen of human and birds, might have been misidentified due to the difficulty of differentiating this bacterium from...
Tue, 09/24/2019 - 03:25
Author(s): Karoline Wagner, Benjamin Preiswerk, Peter M. Keller, Bettina SchulthessAbstractLine probe assays enable rapid detection of drug-resistant Mycobacterium tuberculosis directly from clinical specimens. This study shows that defining threshold values in microscopic examination or PCR detection of M. tuberculosis optimizes line probe assay efficiency, thereby avoiding costs and loss of...
Tue, 09/24/2019 - 03:25
Author(s): Danniele L. Vale, Daniel S. Dias, Amanda S. Machado, Patrícia A.F. Ribeiro, Daniela P. Lage, Lourena E. Costa, Bethina T. Steiner, Grasiele S.V. Tavares, Fernanda F. Ramos, Abel Martínez-Rodrigo, Miguel A. Chávez-Fumagalli, Rachel B. Caligiorne, Danielle F. de Magalhães-Soares, Julia A.G. Silveira, Ricardo A. Machado-de-Ávila, Antônio L. Teixeira, Eduardo A.F. CoelhoAbstractThe...
Tue, 09/24/2019 - 03:25
Author(s): Lindsay M. Avery, Christina A. Sutherland, David P. NicolauAbstractIntravenous fosfomycin is undergoing clinical development in the United States for treatment of complicated urinary tract infections (cUTIs) and may be prescribed as a component of dual antibiotic regimens against carbapenemase-producing Enterobacteriaceae (CPE). Fosfomycin, aztreonam, cefepime, ceftazidime, ceftazidime...
Tue, 09/24/2019 - 03:25
Author(s): Sirlei G. Marques, Maria Rosa Q. Bomfim, Conceição de Maria P.S. Azevedo, Cleide Viviane B. Martins, Ana Claudia G. Marques, Azizedite G. Gonçalves, Vania A. Vicente, Alcione M. dos Santos, Marliete C. Costa, Gustavo J.C. Freitas, Daniel A. Santos, Maria A. de Resende-StoianoffAbstractChromoblastomycosis (CBM) is a chronic subcutaneous infection caused by melanotic fungi, affecting...